Jianhong Qin, Chaojuan Liang, Xiaoyu Jiang, Zhizong Pan, Lida Mo
{"title":"Application of Cystatin C Combined with Homocysteine Detection in AIDS and Tuberculosis Complicated with Hypertension","authors":"Jianhong Qin, Chaojuan Liang, Xiaoyu Jiang, Zhizong Pan, Lida Mo","doi":"10.4236/abb.2023.144011","DOIUrl":"https://doi.org/10.4236/abb.2023.144011","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70469960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"“Too Soon on Earth”: A Biophilosophical Model of Schizophrenia. Some Implications for Humanoid Robots","authors":"B. Mitterauer","doi":"10.4236/abb.2023.141003","DOIUrl":"https://doi.org/10.4236/abb.2023.141003","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70470081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tianzhi Zhang, Chao‐Zhao Liang, Guangchang Shan, Danting Su
{"title":"Clinicopathologic Characteristics of Differentiated Thyroid Carcinoma in Children and Adolescents","authors":"Tianzhi Zhang, Chao‐Zhao Liang, Guangchang Shan, Danting Su","doi":"10.4236/abb.2023.144009","DOIUrl":"https://doi.org/10.4236/abb.2023.144009","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70469851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tovar-Hernández Karla, Ruíz-Cruz Matilde, M. Meraz-Ríos
{"title":"Epigenetic and Posttranscriptional Regulation in Retinoblastoma","authors":"Tovar-Hernández Karla, Ruíz-Cruz Matilde, M. Meraz-Ríos","doi":"10.4236/abb.2023.144013","DOIUrl":"https://doi.org/10.4236/abb.2023.144013","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70470057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adaptation to Fluctuating Neuronal Signal Traffic for Brain Connectivity","authors":"G. Werner, B. Mitterauer","doi":"10.4236/abb.2023.145015","DOIUrl":"https://doi.org/10.4236/abb.2023.145015","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70470135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Baicalein Reduces Metastasis and Heightens Caspase-Induced Apoptosis in Human Colorectal Cancer Cells","authors":"Dylan Fei, Wei Zhu","doi":"10.4236/abb.2023.146019","DOIUrl":"https://doi.org/10.4236/abb.2023.146019","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70470441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mitonucleon-initiated dome formation involves structural changes occurring over a 20 to 24 hour period in monolayer cells induced by a serum factor. The earliest observable change is the fusion of monolayer cells into a syncytium in which nuclei aggregate and become surrounded by a membrane that stains for endogenous biotin. Each of these structures is further surrounded by a fraction of the mitochondria that arise in the syncytium following initiation of dome formation. The mitochondria fuse around the chromatin aggregate in a structure we have called a mitonucleon. Within mitonucleons, a gaseous vacuole is generated that can be seen in protrusions of the apical membrane pressuring chromatin into a pyknotic state. Eventually that pressure, together with whatever enzymatic changes have occurred in the bolus of chromatin, results in DNA fragmentation. The fragments drawn out through the syncytium by a unipolar spindle are arrayed in a configuration that appears open both to epigenetic changes and to DNA repair and replication by polyteny. The fragmented DNA stretched across the syncytial space, hardly detectable by light microscopy, becomes visible approximately half way through the differentiation as the filaments thicken in what looks like replication by polyteny. This “recycling” of attached monolayer cells into detached dome cells must include DNA replication since the number of cells in the resulting domes is greater than the number of monolayer cells by 30% or more. The resulting DNA associates into a mass of chromatin which will “segment” into polyploid structures and then into what appear to be diploid nuclei over a
{"title":"Megamitochondria Initiate Differentiation of Monolayer Cells into Detached Dome Cells That Proliferate by a Schizogony-Like Amitotic Process","authors":"H. Fleming","doi":"10.4236/abb.2023.145016","DOIUrl":"https://doi.org/10.4236/abb.2023.145016","url":null,"abstract":"Mitonucleon-initiated dome formation involves structural changes occurring over a 20 to 24 hour period in monolayer cells induced by a serum factor. The earliest observable change is the fusion of monolayer cells into a syncytium in which nuclei aggregate and become surrounded by a membrane that stains for endogenous biotin. Each of these structures is further surrounded by a fraction of the mitochondria that arise in the syncytium following initiation of dome formation. The mitochondria fuse around the chromatin aggregate in a structure we have called a mitonucleon. Within mitonucleons, a gaseous vacuole is generated that can be seen in protrusions of the apical membrane pressuring chromatin into a pyknotic state. Eventually that pressure, together with whatever enzymatic changes have occurred in the bolus of chromatin, results in DNA fragmentation. The fragments drawn out through the syncytium by a unipolar spindle are arrayed in a configuration that appears open both to epigenetic changes and to DNA repair and replication by polyteny. The fragmented DNA stretched across the syncytial space, hardly detectable by light microscopy, becomes visible approximately half way through the differentiation as the filaments thicken in what looks like replication by polyteny. This “recycling” of attached monolayer cells into detached dome cells must include DNA replication since the number of cells in the resulting domes is greater than the number of monolayer cells by 30% or more. The resulting DNA associates into a mass of chromatin which will “segment” into polyploid structures and then into what appear to be diploid nuclei over a","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70469677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Sikka, S. Paul, A. Jerome, D. Mishra, K. K. Chaturvedi, I. Singh, Anil Rai
{"title":"Functional Genes in Relation to Residual Feed Intake in Murrah Buffalo Heifers","authors":"P. Sikka, S. Paul, A. Jerome, D. Mishra, K. K. Chaturvedi, I. Singh, Anil Rai","doi":"10.4236/abb.2023.144014","DOIUrl":"https://doi.org/10.4236/abb.2023.144014","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70470114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigating a Vitamin D Delivery Toothpaste Using a Penetration Enhancer Compound","authors":"Naree Lee, Jongbin Lee","doi":"10.4236/abb.2023.141001","DOIUrl":"https://doi.org/10.4236/abb.2023.141001","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70469559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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