Mohammed Al-Zharani, M. Mubarak, H. A. Rudayni, M. M. Abdelwahab, M. Al-Eissa
{"title":"Intoxication Induced by Urea Containing Diets in Broiler Chickens: Effect on Weight Gain, Feed Conversion Ratio, Hematological and Biochemical Profiles","authors":"Mohammed Al-Zharani, M. Mubarak, H. A. Rudayni, M. M. Abdelwahab, M. Al-Eissa","doi":"10.4236/abb.2023.143007","DOIUrl":"https://doi.org/10.4236/abb.2023.143007","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70469783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is Escalated Radiation Dose in Definitive Chemoradiotherapy Better for Inoperable Esophageal Carcinoma? A Meta-Analysis and Systematic Review","authors":"Xiaochuan Gan, Qitao Gou, Jing Zhu, Tao Zhang","doi":"10.4236/abb.2023.144012","DOIUrl":"https://doi.org/10.4236/abb.2023.144012","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70470013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Confocal Laser Endomicroscopy in the Field of Esophageal Diseases","authors":"Peiting Xue, Xiu-li Zuo","doi":"10.4236/abb.2023.146017","DOIUrl":"https://doi.org/10.4236/abb.2023.146017","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70470357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Isolation, Examination and Characterization of Actinomycetes as a Source of Antimicrobial Agents from Libyan Soil","authors":"Galal S. Salem, Saleh. H. Baiu, A. A. Ali","doi":"10.4236/abb.2023.146020","DOIUrl":"https://doi.org/10.4236/abb.2023.146020","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70470459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The research investigation was carried out in the experimental area of Sher-e-Bangla Agricultural university, Sher-e-Bangla Nagar, Dhaka-1207, during the late Rabi season Mid December to May 2018 to study the genetic diversity with cluster analysis for the 35 maize genotypes as experimental materials that were laid out in Randomized Complete Block Design (RCBD) with three replica-tions. The research work was oriented to calculate and estimate the yield fac-tor through analyzing genetic diversity involving the yield contributing characters. The maximum yield per plant (117.51 g) was estimated in the genotype G12 (Pacific) and the minimum yield per plant (51.89 g) was recorded in the genotype G17 (Dekalb Super). Due to the crossing among the 35 maize genotypes, a wide range of divergence was observed in this experiment. The highest genotypes were included in cluster number V with 12 genotypes: BHM-5, PAC-60, Pacific-98, HP-222, Khai Bhutta, AS-999, Pioneer, Duranta, Kaveri 218, Chamak-07 and Golden-984. Here, the intra cluster distance was observed in cluster I (1.23), II (0.00), III (0.76), IV (2.08) and V (1.89) respectively. The highest intra cluster was recorded in cluster IV (2.08) and the lowest in
{"title":"Genetic Diversity with Cluster Analysis of Maize Genotypes (<i>Zea mays</i> L.)","authors":"Sumayea Khan, F. Mahmud, Tahmina Ahmmed","doi":"10.4236/abb.2022.137017","DOIUrl":"https://doi.org/10.4236/abb.2022.137017","url":null,"abstract":"The research investigation was carried out in the experimental area of Sher-e-Bangla Agricultural university, Sher-e-Bangla Nagar, Dhaka-1207, during the late Rabi season Mid December to May 2018 to study the genetic diversity with cluster analysis for the 35 maize genotypes as experimental materials that were laid out in Randomized Complete Block Design (RCBD) with three replica-tions. The research work was oriented to calculate and estimate the yield fac-tor through analyzing genetic diversity involving the yield contributing characters. The maximum yield per plant (117.51 g) was estimated in the genotype G12 (Pacific) and the minimum yield per plant (51.89 g) was recorded in the genotype G17 (Dekalb Super). Due to the crossing among the 35 maize genotypes, a wide range of divergence was observed in this experiment. The highest genotypes were included in cluster number V with 12 genotypes: BHM-5, PAC-60, Pacific-98, HP-222, Khai Bhutta, AS-999, Pioneer, Duranta, Kaveri 218, Chamak-07 and Golden-984. Here, the intra cluster distance was observed in cluster I (1.23), II (0.00), III (0.76), IV (2.08) and V (1.89) respectively. The highest intra cluster was recorded in cluster IV (2.08) and the lowest in","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70468705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. R. Kitimu, P. Kirira, Ahmed A. Abdille, Judith Sokei, D. Ochwang’i, P. Mwitari, A. Makanya, N. Maina
Background: Nanotechnology symbolizes a broad discipline with enormous potential in cancer treatment bridging one of the bottlenecks of traditional approaches in cancer therapy which is an inability to deliver adequate quanti-ties of anti-cancer drugs to the tumor area. Studies on nanoparticles indicate their importance in cancer angiogenesis and metastasis. Aim: The present study assessed anti-angiogenesis and anti-metastatic effects of biogenic silver nanoparticles (AgNPs) synthesized from neem plant (Azadirachta indica). Methods: Chicken chorioallantoic membrane (CAM) and two-dimensional (2D) wound healing assays were used to study anti-angiogenic and an-ti-metastatic effects of the AgNPs respectively. Twenty-four fertilized eggs were divided into four groups: two biogenic AgNPs treatments at 100 µg/ml and 200 µg/ml; negative control (1% DMSO) and positive control (cyclo-phosphamide). 2D wound healing assay, DU145 human prostate cells were grown in Dulbecco’s Modified Eagle’s Medium supplemented with 10% Fetal Bovine Serum. Results: Biogenic AgNPs demonstrated anti-angiogenic effects in a dose-dependent manner in the parameters generated from the CAM images. Also, qRT-PCR revealed down-regulation of iNOS and VEGF genes. The 2-dimensional wound healing assay showed inhibition of migration and motility of the DU145 cells for the 72-hours of assessment. Conclusion: The present study postulates that the biogenic AgNPs can prevent angiogenesis by inactivation of VEGF-NO and VEGF/VEGF-R pathways while inhibiting cell migration and metastasis.
{"title":"Anti-Angiogenic and Anti-Metastatic Effects of Biogenic Silver Nanoparticles Synthesized Using <i>Azadirachta indica</i>","authors":"S. R. Kitimu, P. Kirira, Ahmed A. Abdille, Judith Sokei, D. Ochwang’i, P. Mwitari, A. Makanya, N. Maina","doi":"10.4236/abb.2022.134010","DOIUrl":"https://doi.org/10.4236/abb.2022.134010","url":null,"abstract":"Background: Nanotechnology symbolizes a broad discipline with enormous potential in cancer treatment bridging one of the bottlenecks of traditional approaches in cancer therapy which is an inability to deliver adequate quanti-ties of anti-cancer drugs to the tumor area. Studies on nanoparticles indicate their importance in cancer angiogenesis and metastasis. Aim: The present study assessed anti-angiogenesis and anti-metastatic effects of biogenic silver nanoparticles (AgNPs) synthesized from neem plant (Azadirachta indica). Methods: Chicken chorioallantoic membrane (CAM) and two-dimensional (2D) wound healing assays were used to study anti-angiogenic and an-ti-metastatic effects of the AgNPs respectively. Twenty-four fertilized eggs were divided into four groups: two biogenic AgNPs treatments at 100 µg/ml and 200 µg/ml; negative control (1% DMSO) and positive control (cyclo-phosphamide). 2D wound healing assay, DU145 human prostate cells were grown in Dulbecco’s Modified Eagle’s Medium supplemented with 10% Fetal Bovine Serum. Results: Biogenic AgNPs demonstrated anti-angiogenic effects in a dose-dependent manner in the parameters generated from the CAM images. Also, qRT-PCR revealed down-regulation of iNOS and VEGF genes. The 2-dimensional wound healing assay showed inhibition of migration and motility of the DU145 cells for the 72-hours of assessment. Conclusion: The present study postulates that the biogenic AgNPs can prevent angiogenesis by inactivation of VEGF-NO and VEGF/VEGF-R pathways while inhibiting cell migration and metastasis.","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70468949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Premarathna, Thilini Rathnathilaka, G. Seneviratne, S. Madawala
{"title":"Engineering Microbial Biofilms for Improved Productivity of Biochemicals Important in Restoration of Degraded Ecosystems","authors":"M. Premarathna, Thilini Rathnathilaka, G. Seneviratne, S. Madawala","doi":"10.4236/abb.2022.133007","DOIUrl":"https://doi.org/10.4236/abb.2022.133007","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70468806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ontogenes and Chromosome Nondisjunction in the <i>D. melanogaster</i> Meiosis","authors":"B. F. Chadov, N. B. Fedorova","doi":"10.4236/abb.2022.138020","DOIUrl":"https://doi.org/10.4236/abb.2022.138020","url":null,"abstract":"","PeriodicalId":65405,"journal":{"name":"生命科学与技术进展(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70469379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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