Pub Date : 2015-01-01DOI: 10.3724/SP.J.1008.2015.00542
Y. Lou, Xuguo Wang, Jinhong Hu
{"title":"Biologic and small molecular agents for simultaneous treatment of psoriasis and psoriatic arthritis: research progress","authors":"Y. Lou, Xuguo Wang, Jinhong Hu","doi":"10.3724/SP.J.1008.2015.00542","DOIUrl":"https://doi.org/10.3724/SP.J.1008.2015.00542","url":null,"abstract":"","PeriodicalId":6893,"journal":{"name":"Academic Journal of Second Military Medical University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69848459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01DOI: 10.3724/SP.J.1008.2015.00581
Cheng-zhong Li
{"title":"Thinking after fighting against 2014 Ebola epidemic in Liberia","authors":"Cheng-zhong Li","doi":"10.3724/SP.J.1008.2015.00581","DOIUrl":"https://doi.org/10.3724/SP.J.1008.2015.00581","url":null,"abstract":"","PeriodicalId":6893,"journal":{"name":"Academic Journal of Second Military Medical University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69849804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01DOI: 10.3724/SP.J.1008.2015.00761
杨可可, 赵海潞, 沈建, 牟学晶
{"title":"Renin-angiotensin system blockade in correction of glucose metabolic disturbance in uninephrectomized rats","authors":"杨可可, 赵海潞, 沈建, 牟学晶","doi":"10.3724/SP.J.1008.2015.00761","DOIUrl":"https://doi.org/10.3724/SP.J.1008.2015.00761","url":null,"abstract":"","PeriodicalId":6893,"journal":{"name":"Academic Journal of Second Military Medical University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69852354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01DOI: 10.3724/SP.J.1008.2015.00794
Mingxian Zhu, W. Lu, Jinglong Li, Qiuping Cheng, G. Hu, Siyao Liu, Sui-de Deng, N. Yu
Objective To investigate the effects of naloxone injected into cisterna magna on S100βprotein and neuronspecific enolase(NSE)levels in serum and the histopathology of brain tissue of rats following cardiopulmonary resuscitation(CPR).Methods Thirty adult male SD rats were randomly divided into 3groups:Sham group,Conventional CPR group(intravenous injection of epinephrine,0.2mg/kg)and Naloxone CPR group(cisterna magna injection of naloxone,2mg/kg).Asphyxiation was used to set up rat cardiac arrest model,and corresponding drugs were given when the resuscitation was carried out.The blood samples were taken from orbital venous plexus at 0.5h,3h,6hand 24 hafter restoration of spontaneous circulation(ROSC).Enzyme-linked immunosorbent assay(ELISA)was used to detect serum levels of S100βprotein and NSE.Brain tissue was taken after the last blood sampling and the pathology of brain was observed by hematoxylineosin(H-E)staining.Results Serum S100βprotein levels of the Conventional CPR group and Naloxone CPR group were significantly higher than those of the Sham group at all time points(P0.01);compared with the Conventional CPR group,S100βprotein levels in Naloxone CPR group were significantly decreased at 3h,6h,and 24 hafter ROSC(P0.05 or P0.01).Serum NSE protein level of the Conventional CPR group at all time points and Naloxone CPR group at 6hand 24 hafter ROSC were significantly higher than those of the Sham group(P0.05 or P0.01).Serum NSE protein levels were significantly decreased at 6hand 24 hafter ROSC in Naloxone CPR group compared with the Conventional CPR group(P0.05 or P0.01).Moreover,hippocampus glial cells of Conventional CPR group were scattered and decreased,with condensed eosinophilic cytoplasm,narrowed nuclues,unclear nucleolus,and swollen and deformed capillaries.However,most nerve cells of Naloxone CPR group had rich cytoplasm and the nucleolus was clear;only a few nerve cells and capillaries showed edema-like changes of different degrees.Conclusion Naloxone injected into cisterna magna has a prominent protective effect on the brain of rats following cardiopulmonary resuscitation.
{"title":"Protective effect of naloxone injected into cisterna magna on brain tissues of rats following cardiopulmonary resuscitation","authors":"Mingxian Zhu, W. Lu, Jinglong Li, Qiuping Cheng, G. Hu, Siyao Liu, Sui-de Deng, N. Yu","doi":"10.3724/SP.J.1008.2015.00794","DOIUrl":"https://doi.org/10.3724/SP.J.1008.2015.00794","url":null,"abstract":"Objective To investigate the effects of naloxone injected into cisterna magna on S100βprotein and neuronspecific enolase(NSE)levels in serum and the histopathology of brain tissue of rats following cardiopulmonary resuscitation(CPR).Methods Thirty adult male SD rats were randomly divided into 3groups:Sham group,Conventional CPR group(intravenous injection of epinephrine,0.2mg/kg)and Naloxone CPR group(cisterna magna injection of naloxone,2mg/kg).Asphyxiation was used to set up rat cardiac arrest model,and corresponding drugs were given when the resuscitation was carried out.The blood samples were taken from orbital venous plexus at 0.5h,3h,6hand 24 hafter restoration of spontaneous circulation(ROSC).Enzyme-linked immunosorbent assay(ELISA)was used to detect serum levels of S100βprotein and NSE.Brain tissue was taken after the last blood sampling and the pathology of brain was observed by hematoxylineosin(H-E)staining.Results Serum S100βprotein levels of the Conventional CPR group and Naloxone CPR group were significantly higher than those of the Sham group at all time points(P0.01);compared with the Conventional CPR group,S100βprotein levels in Naloxone CPR group were significantly decreased at 3h,6h,and 24 hafter ROSC(P0.05 or P0.01).Serum NSE protein level of the Conventional CPR group at all time points and Naloxone CPR group at 6hand 24 hafter ROSC were significantly higher than those of the Sham group(P0.05 or P0.01).Serum NSE protein levels were significantly decreased at 6hand 24 hafter ROSC in Naloxone CPR group compared with the Conventional CPR group(P0.05 or P0.01).Moreover,hippocampus glial cells of Conventional CPR group were scattered and decreased,with condensed eosinophilic cytoplasm,narrowed nuclues,unclear nucleolus,and swollen and deformed capillaries.However,most nerve cells of Naloxone CPR group had rich cytoplasm and the nucleolus was clear;only a few nerve cells and capillaries showed edema-like changes of different degrees.Conclusion Naloxone injected into cisterna magna has a prominent protective effect on the brain of rats following cardiopulmonary resuscitation.","PeriodicalId":6893,"journal":{"name":"Academic Journal of Second Military Medical University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69852860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01DOI: 10.3724/SP.J.1008.2015.00805
Hu Yang, J. You, Mao-hua Huang, X. Duan, Jun Yang, H. Bian
{"title":"Laparoscopic diagnosis and treatment of enteric intussusception in children","authors":"Hu Yang, J. You, Mao-hua Huang, X. Duan, Jun Yang, H. Bian","doi":"10.3724/SP.J.1008.2015.00805","DOIUrl":"https://doi.org/10.3724/SP.J.1008.2015.00805","url":null,"abstract":"","PeriodicalId":6893,"journal":{"name":"Academic Journal of Second Military Medical University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69853366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01DOI: 10.3724/SP.J.1008.2015.00378
Yu‐zhao Wang, Yin Liu, Ying-jun Guo, Shu-han Sun
{"title":"Annexin A7 inhibits proliferation of hepatoma cellsviabinding with IGFBP2","authors":"Yu‐zhao Wang, Yin Liu, Ying-jun Guo, Shu-han Sun","doi":"10.3724/SP.J.1008.2015.00378","DOIUrl":"https://doi.org/10.3724/SP.J.1008.2015.00378","url":null,"abstract":"","PeriodicalId":6893,"journal":{"name":"Academic Journal of Second Military Medical University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69846357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To study the effect of nano-silver active carbon fiber dressings on wound healing in bedsore wound animal models.Methods Adult SD rats were used and bedsore wound models were made on their back;the animals were then randomly divided into 5groups(n=10)according to different materials of the wound dressing and treatment.Groups were treated with nano-silver active carbon dressings,nano-silver dressings,active carbon dressings,Vaseline chlorhexidine dressings,or blank control.The wound healing situation,contents of angiogenic factors and inflammatory factors in wound tissues were compared among the 5groups.Results Wound healing time and the healing rates were different among the 5groups,with the healing time of rats in nano-silver active carbon dressing group being significantly shorter than those in the other 4groups(P0.05).On the 3rd,7th,14 th and 21 st days after bedsore wound modeling,the healing rates of nano-silver active carbon dressing group were significantly higher than those of the other 4groups(P0.05).The levels of angiogenesis factors and inflammatory factors were different in wound tissues of five groups,with the contents of VEGFA,VEGFB and VEGFC mRNA in nano-silver active carbon dressing group being significantly higher and the contents of TNF-α,IL-2and IL-8mRNA being significantly lower than those of the other 4groups(P0.05).Conclusion The prepared nano-silver active carbon fiber dressing can help to improve pressure ulcer wound healing,relieve wound inflammation,and promote angiogenesis in the wound;it may serve as an ideal material for treating bedsore wound.
{"title":"Nano-silver active carbon fiber dressings improving bedsore wound healing in rats","authors":"Ying Wang, Jian-xing Song, Jiang-ping Chen, Xiaojin Lou","doi":"10.3724/SP.J.1008.2015.01051","DOIUrl":"https://doi.org/10.3724/SP.J.1008.2015.01051","url":null,"abstract":"Objective To study the effect of nano-silver active carbon fiber dressings on wound healing in bedsore wound animal models.Methods Adult SD rats were used and bedsore wound models were made on their back;the animals were then randomly divided into 5groups(n=10)according to different materials of the wound dressing and treatment.Groups were treated with nano-silver active carbon dressings,nano-silver dressings,active carbon dressings,Vaseline chlorhexidine dressings,or blank control.The wound healing situation,contents of angiogenic factors and inflammatory factors in wound tissues were compared among the 5groups.Results Wound healing time and the healing rates were different among the 5groups,with the healing time of rats in nano-silver active carbon dressing group being significantly shorter than those in the other 4groups(P0.05).On the 3rd,7th,14 th and 21 st days after bedsore wound modeling,the healing rates of nano-silver active carbon dressing group were significantly higher than those of the other 4groups(P0.05).The levels of angiogenesis factors and inflammatory factors were different in wound tissues of five groups,with the contents of VEGFA,VEGFB and VEGFC mRNA in nano-silver active carbon dressing group being significantly higher and the contents of TNF-α,IL-2and IL-8mRNA being significantly lower than those of the other 4groups(P0.05).Conclusion The prepared nano-silver active carbon fiber dressing can help to improve pressure ulcer wound healing,relieve wound inflammation,and promote angiogenesis in the wound;it may serve as an ideal material for treating bedsore wound.","PeriodicalId":6893,"journal":{"name":"Academic Journal of Second Military Medical University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69857982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01DOI: 10.3724/SP.J.1008.2015.01034
Yong Liao, Qing-long Tang, Jian-jun Li, Yi Luo, Rongya Yang
{"title":"A PubMed-based bibliometric analysis on research of pruritus","authors":"Yong Liao, Qing-long Tang, Jian-jun Li, Yi Luo, Rongya Yang","doi":"10.3724/SP.J.1008.2015.01034","DOIUrl":"https://doi.org/10.3724/SP.J.1008.2015.01034","url":null,"abstract":"","PeriodicalId":6893,"journal":{"name":"Academic Journal of Second Military Medical University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69858303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01DOI: 10.3724/SP.J.1008.2015.01117
Chong Ni, Shi-chang Guo, Yan Du, G. Cao
{"title":"Role of diet and nutrition in the risk of inflammation-to-cancer","authors":"Chong Ni, Shi-chang Guo, Yan Du, G. Cao","doi":"10.3724/SP.J.1008.2015.01117","DOIUrl":"https://doi.org/10.3724/SP.J.1008.2015.01117","url":null,"abstract":"","PeriodicalId":6893,"journal":{"name":"Academic Journal of Second Military Medical University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69858532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preparation and in vitro evaluation of pancreatic cancer-targeted nano-scale ultrasound contrast agent","authors":"Chuling Hu, Zhongjian Chen, Zongguang Tai, Yuan Gao, Shen Gao, Min-min Zhang","doi":"10.3724/SP.J.1008.2015.01277","DOIUrl":"https://doi.org/10.3724/SP.J.1008.2015.01277","url":null,"abstract":"","PeriodicalId":6893,"journal":{"name":"Academic Journal of Second Military Medical University","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69858596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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