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Simulation method of urban evacuation based on mesoscopic cellular automata 基于介观元胞自动机的城市疏散模拟方法
IF 1 4区 物理与天体物理 Q3 PHYSICS, MULTIDISCIPLINARY Pub Date : 2023-11-17 DOI: 10.7498/APS.70.20210018
Lu Wei, Wang Jing-Hui, Fang Zhi-ming, Mao Dun
This study integrates pedestrian flow characteristics to formulate a mesoscopic cellular automata model tailored for simulating evacuations in large-scale scenarios. Departing from the conventional planar grid cell division, the model employs road cell segmentation, thereby physically enlarging the dimensions of individual cells. This augmentation accommodates an increased occupancy of individuals per cell, representing pedestrian flow parameters within each cell through state variables. The source loading cell facilitates the simulation of pedestrian behavior transitioning from buildings to roads during an actual evacuation event, while the unloading cell situated at the exit removes evacuees from the system. The continuity equation for state transitions comprehensively encapsulates the dynamics of pedestrians throughout the evacuation process. Potential challenges in actual evacuation processes are identified through the simulation, offering valuable insights for improvement. This research aims to contribute to a more effective and informed approach to evacuation planning and management.
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引用次数: 2
Medium Correction to Gravitational Form Factors 重力形状因子的介质校正
IF 1 4区 物理与天体物理 Q3 PHYSICS, MULTIDISCIPLINARY Pub Date : 2023-02-24 DOI: 10.7498/aps.72.20222473
Shu Lin, Jiayuan Tian
We generalize the gravitational form factor for chiral fermion in vacuum, which reproduces the well-known spin-vorticity coupling. We also calculate radiative correction to the gravitational form factors in quantum electrodynamics plasma. We find two structures in the form factors contributing to the scattering amplitude of fermion in vorticity field, one is from the fermon self-energy correction, pointing to suppression of spin-vorticity coupling in medium; the other strucutre comes from graviton-fermion vertex correction, which does not adopt potential interpretation, but corresponds to transition matrix element between initial and final states. Both structures contribute to chiral vortical effect. The net effect is that radiative correction enhances the chiral vortical effect. Our results claify the relation and difference between spin-vorticity coupling and chiral vortical effect from the perspective of form factors. We also discuss the application of the results in QCD plasma, indicating radiative correction might have an appreciable effect in spin polarization effect in heavy ion collisions.
我们推广了真空中手性费米子的引力形式因子,它再现了众所周知的自旋涡耦合。我们还计算了量子电动力学等离子体中引力形状因子的辐射修正。我们发现在涡旋场中影响费米子散射振幅的形式因素中有两种结构,一种是来自费米子的自能修正,表明介质中自旋涡度耦合受到抑制;另一种结构来自引力子-费米子顶点校正,它不采用势解释,而是对应于初态和终态之间的跃迁矩阵元。这两种结构都有助于产生手性旋涡效应。净效应是辐射校正增强了手性旋涡效应。我们的研究结果从形状因素的角度阐明了自旋涡耦合与手性涡效应的关系和区别。我们还讨论了结果在QCD等离子体中的应用,表明辐射校正可能对重离子碰撞中的自旋极化效应有明显的影响。
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引用次数: 1
Research progress on the laser system of the cold atomic clock in China Space Station 中国空间站冷原子钟激光系统研究进展
IF 1 4区 物理与天体物理 Q3 PHYSICS, MULTIDISCIPLINARY Pub Date : 2023-01-01 DOI: 10.7498/aps.72.20230412
Liu Yun, Wang Wen-Hai, He De-Jing, Zhou Yong-Zhuang, Shen Yong, Zou Hong-Xin
The first space optical clock (SOC) in the world developed in China, which is composed by five subsystems, including an optical unit, a physics unit, an electronic control unit, a space optical frequency comb, and an ultrastable laser, has been successfully launched with the Mengtian space laboratory into the China Space Station (CSS). Compact and stable lasers are key elements for the operation of the SOC. The optical unit consists of 5 lasers at 461 nm, 679 nm, 689 nm, 707nm, and 813 nm. With a synchronous-tuning-like scheme, high quality external cavity diode lasers (ECDL) have been developed as the seeds. The linewidth of the lasers is suppressed to the order of 100 kHz, and the mode-hop-free tuning range reaches 20 GHz, which meet the requirements of the SOC. With careful mechanical and thermal design, the stability of the lasers against vibration and temperature fluctuation has been sufficiently promoted to confront the challenge of rocket launching. While the power from the ECDL is sufficient for 679 nm and 707 nm repump lasers, additional injection lock is utilized for the 461 nm and 689 nm lasers to amplify the power of the seeds to more than 600 mW, so that efficient first and second stage Doppler cooling can be achieved. To generate an optical lattice with deep enough potential well, over 800 mW 813 nm lasers is required. Therefore, a semiconductor tapered amplifier is adopted to amplify the seed to more than 2 W, so as to cope with various losses of the coupling optics. The wavelength and output power of the 5 lasers are monitored and feedback-controlled by the electronic control unit. All the modules are designed and manufactured as orbital replaceable units, which can be easily replaced by astronauts in case failure occurs. Now the lasers are all turned on and operates normally in CSS. More data of the SOC will be obtained in the near future. At present stage, according to our evaluation, the continuous operation time of the SOC is limited by the injection locked lasers, which are relatively vulnerable to mode hopping. Hopefully this problem can be solved by improving the laser diode manufacturing technology, or developing fiber lasers with compact frequency conversion modules.
由光学单元、物理单元、电子控制单元、空间光频梳和超稳激光器等5个子系统组成的世界首个空间光时钟(SOC)已随蒙田空间实验室成功发射进入中国空间站。紧凑和稳定的激光器是SOC运行的关键要素。光单元由461 nm、679 nm、689 nm、707nm和813 nm波长的5个激光器组成。利用类似同步调谐的方案,高质量的外腔二极管激光器(ECDL)作为种子被开发出来。该激光器的线宽被抑制到100 kHz数量级,无跳模调谐范围达到20 GHz,满足SOC的要求。通过精心的机械和热设计,充分提高了激光器对振动和温度波动的稳定性,以应对火箭发射的挑战。虽然ECDL的功率足以用于679 nm和707 nm的再泵激光器,但额外的注入锁用于461 nm和689 nm激光器,将种子的功率放大到600 mW以上,因此可以实现高效的第一和第二阶段多普勒冷却。为了产生具有足够深的势阱的光学晶格,需要超过800 mW的813 nm激光器。因此,采用半导体锥形放大器将种子放大到2w以上,以应对耦合光学器件的各种损耗。电子控制单元对5种激光器的波长和输出功率进行监测和反馈控制。所有的模块都被设计和制造为轨道可更换单元,如果发生故障,宇航员可以很容易地更换。现在激光器全部打开并在CSS中正常运行。更多的SOC数据将在不久的将来获得。现阶段,根据我们的评估,SOC的连续工作时间受到注入锁定激光器的限制,这些激光器相对容易受到模式跳变的影响。希望通过改进激光二极管制造技术,或开发具有紧凑变频模块的光纤激光器来解决这一问题。
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引用次数: 0
Compact broadband bandpass filter with wide stopband based on halberd-shaped spoof surface plasmon polariton 基于戟形欺骗表面等离子激元极化子的紧凑型宽阻带带通滤波器
IF 1 4区 物理与天体物理 Q3 PHYSICS, MULTIDISCIPLINARY Pub Date : 2023-01-01 DOI: 10.7498/aps.72.20222291
Shu-Peng Sun, Yongzhi Cheng, Hui Luo, Fu Chen, Xiangcheng Li
In this paper, a compact broadband bandpass filter with wide out-of-band rejection characteristics based on halberd-shaped spoof surface plasmon polariton (SSPP) is proposed. The filtering structure is achieved by etching a periodic halberd-shaped groove at the bottom of the substrate and a microstrip-to-slot line transition with a crescent-shaped patch at the top. Compared with the traditional dumbbell-shaped SSPP, the halberd-shaped SSPP has good slow-wave property, and the designed bandpass filter based on halberd-shaped SSPP can achieve a more compact size. The upper cutoff frequency and lower cutoff frequency of the passband can be adjusted by regulating the SSPP structure and the transition structure from microstrip-to-slot line, respectively. The simulation results show that the center frequency of broadband bandpass filter is 2.85 GHz, with the relative bandwidth of 130%, and the return loss in the passband is better than –10 dB, and the extreme strong out-of-band rejection of –40 dB from 5.6 GHz to 20 GHz. The size of the broadband bandpass filter is compact, only 1.08λg×0.39λg, where λg is the wavelength at the center frequency. In order to verify the effectiveness of the wideband bandpass filter, the traditional printed circuit board technology is used to fabricate the wideband bandpass filter. The measurement results are in good agreement with the simulation results, verifying the feasibility of the design. The proposed broadband bandpass filter shows promising prospects for developing SSPP functional devices and circuits at microwave frequencies.
提出了一种基于戟形欺骗表面等离子激元(SSPP)的窄带带通滤波器,具有宽带外抑制特性。该滤波结构是通过在衬底底部蚀刻周期性戟形凹槽和在顶部蚀刻具有月牙形贴片的微带到槽线过渡来实现的。与传统的哑铃形SSPP相比,戟形SSPP具有良好的慢波性能,基于戟形SSPP设计的带通滤波器可以实现更紧凑的尺寸。通带的上截止频率和下截止频率可以分别通过调节SSPP结构和微带到槽线的过渡结构来调节。仿真结果表明,该宽带带通滤波器的中心频率为2.85 GHz,相对带宽为130%,在5.6 GHz ~ 20 GHz范围内回波损耗优于-10 dB,带外抑制极强,为-40 dB。宽带带通滤波器尺寸紧凑,只有1.08λg×0.39λg,其中λg为中心频率处的波长。为了验证宽带带通滤波器的有效性,采用传统的印刷电路板技术制作宽带带通滤波器。测量结果与仿真结果吻合较好,验证了设计的可行性。所提出的宽带带通滤波器在开发微波频率的SSPP功能器件和电路方面具有良好的前景。
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引用次数: 1
Transport of closed ring containing chiral active particles under transversal temperature difference 含手性活性粒子闭环在横向温差下的输运
IF 1 4区 物理与天体物理 Q3 PHYSICS, MULTIDISCIPLINARY Pub Date : 2023-01-01 DOI: 10.7498/aps.72.20221772
Jing-Jing Liao, Qi Kang, Fei Luo, Fu-Jun Lin
Active matter is a new and challenging field of physics. Chiral active particle experiences a constant torque and performs circular motion due to the self-propulsion force not aligning with the propulsion direction. Recently, most of studies of the active particle systems focused on constant temperature, but did not take into consideration the constraints by the barriers. In our work, the rectification of a ring containing chiral active particles with transversal temperature difference is numerically investigated in a two-dimensional periodic channel. It is found that the ring powered by chiral active particles can be rectified by the transversal temperature difference and the direction of the transport is determined by the chirality of active particles. The average velocity is a peaked function of angular velocity, the temperature of the lower wall or temperature difference. The transport behaviors of the ring containing one chiral active particle is qualitatively different from those of the ring containing several particles. Especially, the ring radius can strongly affect the transport behaviors. For the ring containing one chiral active particle, the interaction between the particle and the ring facilitates the rectification of the ring when the circular trajectory radius of the chiral particle is large. The average velocity decreases with the increase of the ring radius because the propelling force to the ring by the particle is small. When the circular trajectory radius is small, the interaction between the particle and the ring suppresses the transport. The speed increases as the ring radius increases because the directional transport comes from the difference in temperature between the upper wall and the lower wall. For the ring containing several particles, the interaction between particles reduces the rectification of the ring. The average velocity increases with the increase of the ring radius due to the interaction between particles decreasing. Remarkably, the velocity of the ring decreases as the particle number increases when the ring radius is small, but is a peaked function when the ring radius is not small. Our results offer new possibilities for manipulating an active particle flow on a microscale, and can be applied practically to propelling carriers and motors by a bath of bacteria or artificial microswimmers, such as hybrid micro-device engineering, drug delivery, micro-fluidics, and lab-on-chip technology.
活性物质是物理学中一个具有挑战性的新领域。由于自推进力与推进方向不一致,手性主动粒子受到恒定的力矩并进行圆周运动。目前对活性粒子体系的研究大多集中在恒温上,而没有考虑势垒的约束。本文研究了二维周期通道中具有横向温差的手性活性粒子环的整流问题。研究发现,手性活性粒子驱动的环可以通过横向温差进行整流,其输运方向由活性粒子的手性决定。平均速度是角速度、下壁温度或温差的峰值函数。含有一个手性活性粒子的环的输运行为与含有多个手性活性粒子的环的输运行为有质的区别。特别是环半径对输运行为有很大的影响。对于含有一个手性活性粒子的环,当手性粒子的圆轨迹半径较大时,粒子与环之间的相互作用有利于环的纠正。由于粒子对环的推进力较小,平均速度随环半径的增大而减小。当圆轨道半径较小时,粒子与环的相互作用抑制了输运。速度随环半径的增大而增大,这是由于定向输运来自上下壁面的温差。对于含有多个粒子的环,粒子间的相互作用降低了环的整流。由于粒子间相互作用的减小,平均速度随环半径的增大而增大。值得注意的是,当环半径较小时,环的速度随粒子数的增加而减小,但当环半径较大时,环的速度为峰值函数。我们的研究结果为在微尺度上操纵主动粒子流提供了新的可能性,并且可以实际应用于通过细菌浴或人工微游泳者来推动载体和马达,例如混合微设备工程,药物输送,微流体和芯片实验室技术。
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引用次数: 0
A compact silicon-based mode converter using bricked subwavelength grating 一种采用砖砌亚波长光栅的紧凑硅基模式转换器
IF 1 4区 物理与天体物理 Q3 PHYSICS, MULTIDISCIPLINARY Pub Date : 2023-01-01 DOI: 10.7498/aps.72.20230673
Lu Meng-jia, Yun Bin-Feng
Facing with the increasing capacity requirements of on-chip optical interconnects, mode division multiplexing technology (MDM), which leverages the different spatial eigenmodes at the same wavelength as independent channels to transmit optical signals, has attracted tremendous interest. Mode-order converters that can convert the fundamental mode to high-order modes are key components in MDM systems. However, it is still very challenging to achieve compact mode-order converters with high performances. Subwavelength grating (SWG) can be equivalent to homogenous material, which has the prominent advantages such as control over birefringence, dispersion and anisotropy, enabling photonic devices with high performance. Wheras the conventional SWG only needs single-etch step, but the implementation of SWG structure usually requires a fabrication resolution of the order of 100 nm and below, which is difficult for current wafer-scale fabrication technology. The anisotropic response of SWG can be further engineered by introducing bricked topology structure, providing an additional degree of freedom in the design. Meanwhile, the requirement of fabrication resolution can also be reduced (>100 nm). In this work, we experimentally demonstrate compact TE0-TE1 and TE0-TE2 mode-order converters using bricked subwavelength grating (BSWG) based on silicon-on-insulator (SOI) with the minimum feature size of the BSWG is 145 nm. In the proposed mode-order converter, a quasi-TE0 mode is generated in the BSWG region, which can be regarded as an effective bridge between the two TE modes to be converted. Flexible mode conversion can be realized by only choosing appropriate structural parameters for specific mode transitions between input/output modes and the quasi-TE0 mode. By combing 3D finite difference time domain (FDTD) and particle swarm optimization (PSO) method, TE0-TE1 and TE0-TE2 mode-order converters are optimal designed. It can convert TE0 mode into TE1 and TE2 mode with conversion length of 9.39 μm and 11.27 μm. The simulation results show that the insertion loss of <1 dB and crosstalk of < ‒ 15 dB are achieved for both TE0-TE1 and TE0-TE2 mode-order converters, the corresponding working bandwidth are 128 nm (1511~1639 nm) and 126 nm (1527~1653 nm), respectively. The measurement results indicate that insertion loss and crosstalk are less than 2.5 dB and -10 dB in a bandwidth of 68 nm (1512~1580 nm, limited by the laser tuning range and grating coupler).
面对片上光互连日益增长的容量需求,利用同一波长的不同空间特征模作为独立通道传输光信号的模分复用技术(MDM)引起了人们的极大兴趣。可以将基本模式转换为高阶模式的模式顺序转换器是MDM系统中的关键组件。然而,实现高性能的紧凑型模阶变换器仍然是非常具有挑战性的。亚波长光栅(SWG)可以等效于均质材料,具有控制双折射、色散和各向异性等突出优点,使光子器件具有高性能。而传统的SWG只需要单步蚀刻,但SWG结构的实现通常需要100 nm及以下的制造分辨率,这对于目前的晶圆级制造技术来说是困难的。通过引入砖状拓扑结构,可以进一步设计SWG的各向异性响应,为设计提供额外的自由度。同时,对制造分辨率的要求也可以降低(>100 nm)。在这项工作中,我们实验展示了紧凑的TE0-TE1和TE0-TE2模式阶转换器,使用基于绝缘体上硅(SOI)的砖状亚波长光栅(BSWG), BSWG的最小特征尺寸为145 nm。在模阶转换器中,在BSWG区域产生一个准te0模式,该模式可以看作是两个待转换TE模式之间的有效桥梁。针对输入/输出模式与准te0模式之间的特定模式转换,只需选择合适的结构参数即可实现柔性模式转换。结合三维时域有限差分(FDTD)和粒子群优化(PSO)方法,对TE0-TE1和TE0-TE2模阶变换器进行了优化设计。可将TE0模式转换为TE1和TE2模式,转换长度分别为9.39 μm和11.27 μm。仿真结果表明,TE0-TE1和TE0-TE2模阶转换器的插入损耗<1 dB,串扰< - 15 dB,相应的工作带宽分别为128 nm (1511~1639 nm)和126 nm (1527~1653 nm)。测量结果表明,在68 nm (1512~1580 nm,受激光调谐范围和光栅耦合器的限制)带宽范围内,插入损耗和串扰分别小于2.5 dB和-10 dB。
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引用次数: 0
Defect Evolution in Y0.5Gd0.5Ba2Cu3O7-δ Layer by H Ion Irradiation H离子辐照Y0.5Gd0.5Ba2Cu3O7-δ层缺陷演化
IF 1 4区 物理与天体物理 Q3 PHYSICS, MULTIDISCIPLINARY Pub Date : 2023-01-01 DOI: 10.7498/aps.72.20221612
Dan Min, 金凡亚, Chen Lun-Jiang, He Yan-Bin, Wan Jun-Hao, Zhang Hong, Zhang Ke-Jia, Yang Yin, Jin Fan-Ya
In order to further improve the superconducting current carrying capacity of REBCO coated conductor under strong magnetic field, ion irradiation is used to generate the pinning center of introduced magnetic flux in the REBCO coated conductor. In this paper, the H-ion irradiation of REBCO second generation high temperature superconductor strip was carried out by using the 320kV high charge state ion synthesis research platform. DB-SPBA combined with Raman spectroscopy was used to measure the change of microstructure in YBCO samples irradiated by H+ions within the range of 5.0×1014~1.0×1016. The positron annihilation parameters in YBCO before and after irradiation were analyzed. It is found that after 100 keV H+ion irradiation, a large number of defects including vacancy, vacancy group or dislocation group are produced in the superconducting layer. The larger the irradiation dose, the more vacancy type defects are produced, the more complex the defect types are, and the annihilation mechanism of positrons in the defects changes. Raman spectroscopy results show that with the increase of H+ion irradiation dose, the oxygen atoms in the coating rearrange, the plane spacing increases, the orthogonal phase structure of the coating is destroyed, and the degree of order decreases. The defects produced by such ion irradiation lay a foundation for the introduction of flux pinning centers. Further research can be carried out in combination with X-ray diffractometer, transmission electron microscope, superconductivity and other testing methods to provide theoretical and practical reference for the optimization of material properties.
为了进一步提高REBCO涂层导体在强磁场作用下的超导载流能力,采用离子辐照的方法在REBCO涂层导体中产生引入磁通量的钉住中心。本文利用320kV高电荷态离子合成研究平台,对REBCO第二代高温超导体带材进行了h离子辐照。采用DB-SPBA结合拉曼光谱法测量了H+离子辐照YBCO样品在5.0×1014~1.0×1016范围内的微观结构变化。分析了YBCO辐照前后的正电子湮灭参数。发现在100 keV H+离子辐照后,超导层中产生了大量的缺陷,包括空位、空位族或位错族。辐照剂量越大,产生的空位型缺陷越多,缺陷类型越复杂,正电子在缺陷中的湮灭机制发生变化。拉曼光谱结果表明,随着H+离子辐照剂量的增加,涂层中的氧原子重新排列,平面间距增大,涂层的正交相结构被破坏,有序度降低。离子辐照产生的缺陷为引入钉钉中心奠定了基础。可以结合x射线衍射仪、透射电镜、超导等测试方法进行进一步的研究,为材料性能的优化提供理论和实践参考。
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引用次数: 0
Research on inversion models of internal solitary wave propagation speed in ocean based on least square method and support vector machine 基于最小二乘法和支持向量机的海洋内孤立波传播速度反演模型研究
IF 1 4区 物理与天体物理 Q3 PHYSICS, MULTIDISCIPLINARY Pub Date : 2023-01-01 DOI: 10.7498/aps.72.20221633
Keda Liang, Tengfei Liu, Zhe Chang, Meng Zhang, ZhiXin Li, Songsong Huang, Jing Wang
The propagation speed is one of the important parameters of the internal solitary waves(ISWs). How to obtain the ISWs speed through optical remote sensing images accurately and quickly is an important problem to be solved. In this paper, we simulate ISWs optical remote sensing imaging and obtain an experimental database and build the ISWs speed inversion models based on a single-scene optical remote sensing image by using the least squares method and the support vector machine. The accuracy of the ISW speed inversion models were tested by using MODIS Image and GF-4 image data of the South China Sea. The study results show that: The least squares ISW speed inversion model can give the regression equation, which is more intuitive and has less accuracy in the water depth range from 300 meters to 399 meters, while the support vector machine ISW speed inversion model has high accuracy in the water depth range from 400 meters to 1200 meters and from 83 meters to 299 meters. Therefore, the two kinds of ISW speed inversion models have different advantages, and can be applied to the inversion of the ISW speed in the real ocean.
传播速度是内孤立波的重要参数之一。如何通过光学遥感影像准确、快速地获取isw速度是一个需要解决的重要问题。本文采用最小二乘法和支持向量机对ISWs光学遥感成像进行仿真,获得实验数据库,建立基于单场景光学遥感图像的ISWs航速反演模型。利用南海MODIS影像和GF-4影像资料,对ISW速度反演模型的精度进行了验证。研究结果表明:最小二乘ISW航速反演模型能给出回归方程,在300米~ 399米水深范围内更为直观,精度较低,而支持向量机ISW航速反演模型在400米~ 1200米和83米~ 299米水深范围内精度较高。因此,两种ISW速度反演模式具有不同的优势,可以应用于实际海洋ISW速度的反演。
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引用次数: 0
A simple DGTD method with the impedance boundary condition 具有阻抗边界条件的简单DGTD方法
IF 1 4区 物理与天体物理 Q3 PHYSICS, MULTIDISCIPLINARY Pub Date : 2023-01-01 DOI: 10.7498/aps.72.20222104
Yang Qian, Wei Bing, Li Linqian, Deng Haochuan
Large-size conductive targets or coated targets are difficult issues in computational electromagnetics. In general, such targets can be classified as multi-scale problems. Multi-scale problems usually consume a large number of computational resources. Researchers are devoted to seeking fast methods for these problems. When the skin depth is less than the size of a conductive target, the tangential components of the electric and magnetic fields over the surface of the target can be correlated by the surface impedance Ẑ. Ẑ is usually a complex function of the frequency, and it can be used to formulate an impedance boundary condition (IBC) to describe iterative equations in time domain methods to avoid the volumetric discretization of the target to improve computational efficiency. This condition is commonly known as the surface impedance boundary condition (SIBC). Similarly, for a conductor with thickness on the order or less than the skin depth, it also has high resource requirements if the target is straightforward volumetric discretization. The transmission impedance boundary condition (TIBC) can be applied to replace a coated object to reduce resource requirements. Thus, volumetric discretization is not required. There are few studies on the IBC scheme in the DGTD method. P. Li discussed the IBC scheme in DGTD, which involves complex matrix operations in the processing of IBC. In the DGTD method, numerical flux is used to transmit data between neighboring elements, and the key to the IBC scheme in DGTD is how to handle numerical flux. We hope to propose a DGTD method with a simple form and matrix-free IBC scheme. The key in dealing with IBC in DGTD is numerical flux. Unlike the literature, the impedance ẐR is not approximated by rational functions in our study. A specfic function ẐR obtained after the derivation in this paper is approximated by rational functions in the Laplace domain using the vector-fitting (VF) method, and its time-domain iteration scheme is given. This approach avoids matrix operations. The TIBC and SIBC processing schemes are given in section 4. The proposed method's advantage is that the upwind flux's standard coefficients are retained, and the complex frequency-time conversion problem is implemented by the vector-fitting method. The one-dimensional and three-dimensional examples also show the accuracy and effectiveness of our work in this paper.
大尺寸导电目标或涂覆目标是计算电磁学中的难题。一般来说,这类目标可以归类为多尺度问题。多尺度问题通常会消耗大量的计算资源。研究人员致力于寻找解决这些问题的快速方法。当蒙皮深度小于导电目标的尺寸时,可以通过表面阻抗Ẑ来关联目标表面上电场和磁场的切向分量。Ẑ通常是频率的复函数,在时域方法中可以用它来建立阻抗边界条件(IBC)来描述迭代方程,避免了目标的体积离散化,提高了计算效率。这种条件通常被称为表面阻抗边界条件(SIBC)。同样,对于厚度为或小于蒙皮深度的导体,如果目标是直接的体积离散化,它也有很高的资源要求。传输阻抗边界条件(TIBC)可用于代替被涂覆物体,以减少资源需求。因此,不需要体积离散化。对于DGTD方法中IBC方案的研究很少。李鹏讨论了DGTD中的IBC方案,其中IBC的处理涉及复杂的矩阵运算。在DGTD方法中,采用数值通量在相邻单元之间进行数据传输,而DGTD中IBC方案的关键是如何处理数值通量。我们希望提出一种具有简单形式和无矩阵IBC方案的DGTD方法。在DGTD中处理IBC的关键是数值通量。与文献不同的是,在我们的研究中,阻抗ẐR不是用有理函数近似的。用向量拟合(vector-fitting, VF)方法在拉普拉斯域中用有理函数逼近了本文推导得到的一个特定函数ẐR,并给出了它的时域迭代格式。这种方法避免了矩阵运算。第4节给出了TIBC和SIBC处理方案。该方法的优点是保留了迎风通量的标准系数,并采用矢量拟合方法实现了复频率-时间转换问题。一维和三维的算例也证明了本文工作的准确性和有效性。
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引用次数: 0
Dual-channel structured illumination super-resolution quantitative FRET imaging 双通道结构照明超分辨率定量FRET成像
IF 1 4区 物理与天体物理 Q3 PHYSICS, MULTIDISCIPLINARY Pub Date : 2023-01-01 DOI: 10.7498/aps.72.20230853
ZEWEI LUO, GE WU, ZHI CHEN, CHINAN DANG, RONG WAN, Tao Yang, ZHENGFEI ZHUANG, AND TONGSHENG CHEN
The Structured Illumination (SI)-based Super Resolution Fluorescence Resonance Energy Transfer (SR-FRET) imaging technique, known as SISR-FRET, enables the investigation of molecular structures and functions in cellular organelles by resolving sub-diffraction FRET signals within living cells. FRET microscopy offers unique advantages for quantitatively detecting dynamic interactions and spatial distribution of biomolecules within living cells. The spatial resolution of conventional FRET microscopy is limited by the diffraction limit, and it can only capture the average behavior of these events within the resolution limits of conventional fluorescence microscopy. SISR-FRET performs sequential linear reconstruction of the three-channel SIM images followed by FRET quantitative analysis using a common localization mask-based filtering approach. This two-step process ensures the fidelity of the reconstructed SR-FRET signals while effectively removing false-positive FRET signals caused by SIM artifacts. However, the slow imaging speed resulting from the switching of excitation-emission channels in SISR-FRET imaging limits its application in fast imaging scenarios. To address this issue, this study proposes a dual-channel structured illumination super-resolution quantitative FRET imaging system and method. By incorporating a FRET dual-channel imaging and registration module into the imaging pathway, spatial switching and channel multiplexing of the SISR-FRET excitation-emission channels are achieved. Combining the image reconstruction algorithm with channel sub-pixel registration correction, the dual-channel SISR-FRET technique enhances the temporal resolution by 3.5 times while preserving the quantitative super-resolution FRET analysis. Experimental results were obtained using a multi-color SIM system to perform super-resolution imaging of living cells expressing mitochondria outer membrane FRET standard plasmids. These experiments validate the improved spatial and temporal resolution of dual-channel SISR-FRET and the fidelity of FRET quantification analysis. In summary, this research presents a novel dual-channel structured illumination super-resolution FRET imaging system and methodology. It overcomes the limitations of slow imaging speed in SISR-FRET by enabling spatial switching and channel multiplexing of excitation-emission channels. The proposed technique enhances the temporal resolution while maintaining quantitative analysis of super-resolution FRET. Experimental validation demonstrates the increased spatial and temporal resolution of dual-channel SISR-FRET and the accuracy of FRET quantification analysis. This advancement contributes to the study of molecular structures and functions in cellular organelles, providing valuable insights into the intricate mechanisms of living cells.
基于结构照明(SI)的超分辨率荧光共振能量转移(SR-FRET)成像技术,被称为SISR-FRET,通过解析活细胞内的亚衍射FRET信号,可以研究细胞器中的分子结构和功能。FRET显微镜为定量检测活细胞内生物分子的动态相互作用和空间分布提供了独特的优势。传统FRET显微镜的空间分辨率受到衍射极限的限制,它只能捕获这些事件的平均行为在传统荧光显微镜的分辨率限制内。SISR-FRET执行三通道SIM图像的顺序线性重建,然后使用基于通用定位掩模的滤波方法进行FRET定量分析。这两步过程确保了重建的SR-FRET信号的保真度,同时有效地去除由SIM伪影引起的假阳性FRET信号。然而,在SISR-FRET成像中,由于激发发射通道的切换导致成像速度较慢,限制了其在快速成像场景中的应用。为了解决这一问题,本研究提出了一种双通道结构照明超分辨率定量FRET成像系统和方法。通过在成像通道中加入FRET双通道成像配准模块,实现了SISR-FRET激发发射通道的空间切换和通道复用。将图像重建算法与通道亚像素配准校正相结合,双通道SISR-FRET技术在保留定量超分辨率FRET分析的同时,将时间分辨率提高了3.5倍。实验结果采用多色SIM系统对表达线粒体外膜FRET标准质粒的活细胞进行超分辨率成像。这些实验验证了双通道SISR-FRET提高的时空分辨率和FRET量化分析的保真度。总之,本研究提出了一种新的双通道结构照明超分辨率FRET成像系统和方法。它通过实现激发发射通道的空间切换和通道复用,克服了SISR-FRET成像速度慢的限制。该技术提高了时间分辨率,同时保持了超分辨率FRET的定量分析。实验验证表明,双通道SISR-FRET提高了空间和时间分辨率,并提高了FRET定量分析的准确性。这一进展有助于细胞器分子结构和功能的研究,为了解活细胞的复杂机制提供有价值的见解。
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