Abstract Orbital pseudotumor represents a benign inflammatory disorder of the orbit, with unspecified etiology, whose clinical presentation can mimic the ocular pathology of Basedow disease, namely Graves’ ophthalmopathy, the two of them representing two of the most common orbital conditions. Imagistic methods and laboratory analyses can establish the diagnosis through orbital MRI images specific for the orbital pseudotumor, especially by dosage of the TSH receptor antibodies (TRAb) which will have increased values in Basedow disease with ocular damage. In both situations, the treatment is represented as a first therapeutic line by administration of corticotherapy in high dosage orally or intravenously, with favorably evolution, which is also observable in the case of our patient who was diagnosed with orbital pseudotumor based on MRI images, with associated thyroid dysfunction with negative TRAb, in which the pulse therapy with Solumedrol has determined the improvement of ocular symptoms and signs.
{"title":"The Efficiency of Pulse Therapy with Glucocorticoids in Inflammatory Orbital Disorders: Case Report","authors":"Ioana-Codruța Lebădă, M. Stanciu","doi":"10.2478/amtsb-2020-0063","DOIUrl":"https://doi.org/10.2478/amtsb-2020-0063","url":null,"abstract":"Abstract Orbital pseudotumor represents a benign inflammatory disorder of the orbit, with unspecified etiology, whose clinical presentation can mimic the ocular pathology of Basedow disease, namely Graves’ ophthalmopathy, the two of them representing two of the most common orbital conditions. Imagistic methods and laboratory analyses can establish the diagnosis through orbital MRI images specific for the orbital pseudotumor, especially by dosage of the TSH receptor antibodies (TRAb) which will have increased values in Basedow disease with ocular damage. In both situations, the treatment is represented as a first therapeutic line by administration of corticotherapy in high dosage orally or intravenously, with favorably evolution, which is also observable in the case of our patient who was diagnosed with orbital pseudotumor based on MRI images, with associated thyroid dysfunction with negative TRAb, in which the pulse therapy with Solumedrol has determined the improvement of ocular symptoms and signs.","PeriodicalId":7091,"journal":{"name":"Acta Medica Transilvanica","volume":"25 1","pages":"22 - 24"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41868937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erika Bimbo-Szuhai, A. Maghiar, M. Botea, A. Huniadi, M. Șandor, Corina Beiușan, I. Macovei, Claudia Teodora Judea Pusta
Abstract Multiple biological parameters were proposed to evaluate the surgical stress response in the early postoperative period. Granulocyte/lymphocyte (G/L) ratio may be a useful marker and widely available. Measuring some of known surgical stress related markers together with G/L ratio we tried to confirm the superiority of laparoscopic approach and efficiency of the G/L ratio monitoring in this period. Materials and methods: 52 colorectal cancer patients who underwent elective surgery in a private clinical hospital were evaluated preoperatively and postoperatively (day 1 and day 5) for the: TNF-α, cortisol, C reactive protein (CRP) and G/L ratio. Results: Only CRP levels were significantly lower in the laparoscopy group in day 1 (74.07 vs 50.32, p=0.0461) and day 5 (18.37 vs 7.32, p=0.0001). The G/L ratio showed strong correlation with CRP levels in all measurements. Conclusions: Measurement of postoperative CRP levels confirmed the reduced surgical stress of laparoscopic colectomy for colorectal cancer in our clinic.
摘要提出了多种生物学参数来评估术后早期的手术应激反应。粒细胞/淋巴细胞（G/L）比率可能是一个有用的标记，并且广泛可用。通过测量一些已知的手术应力相关标志物以及G/L比率，我们试图证实腹腔镜入路的优越性和该时期G/L比率监测的有效性。材料和方法：对52例在私立临床医院接受择期手术的癌症患者术前和术后（第1天和第5天）的TNF-α、皮质醇、C反应蛋白（CRP）和G/L比值进行评估。结果：腹腔镜组在第1天（74.07 vs 50.32，p=0.0461）和第5天（18.37 vs 7.32，p=0.0001）只有CRP水平显著降低。在所有测量中，G/L比与CRP水平呈强相关性。结论：术后CRP水平的测定证实了腹腔镜癌症结肠切除术减轻了手术压力。
{"title":"The Perioperative Comparative Evolution of Surgical Stress Markers in Colorectal Cancer Patients Between Classical and Laparoscopic Surgery","authors":"Erika Bimbo-Szuhai, A. Maghiar, M. Botea, A. Huniadi, M. Șandor, Corina Beiușan, I. Macovei, Claudia Teodora Judea Pusta","doi":"10.2478/amtsb-2020-0072","DOIUrl":"https://doi.org/10.2478/amtsb-2020-0072","url":null,"abstract":"Abstract Multiple biological parameters were proposed to evaluate the surgical stress response in the early postoperative period. Granulocyte/lymphocyte (G/L) ratio may be a useful marker and widely available. Measuring some of known surgical stress related markers together with G/L ratio we tried to confirm the superiority of laparoscopic approach and efficiency of the G/L ratio monitoring in this period. Materials and methods: 52 colorectal cancer patients who underwent elective surgery in a private clinical hospital were evaluated preoperatively and postoperatively (day 1 and day 5) for the: TNF-α, cortisol, C reactive protein (CRP) and G/L ratio. Results: Only CRP levels were significantly lower in the laparoscopy group in day 1 (74.07 vs 50.32, p=0.0461) and day 5 (18.37 vs 7.32, p=0.0001). The G/L ratio showed strong correlation with CRP levels in all measurements. Conclusions: Measurement of postoperative CRP levels confirmed the reduced surgical stress of laparoscopic colectomy for colorectal cancer in our clinic.","PeriodicalId":7091,"journal":{"name":"Acta Medica Transilvanica","volume":"25 1","pages":"50 - 53"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45516608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Considering actual SARS-COV 2 pandemic, the comfort and time of the female patient’ trend is to minimize the time spent in the doctor’s office, so that auto-testing is a solving problem in this context. This paper aims at the importance of self-collected urine and vaginal samples, since actual studies are showing that is a complementary method in HPV-testing and a screening method for prevention of cervical cancer. Genital HPV infection is responsible for approximately 99% of cervical cancers, and is considered a sexually transmitted disease. Given that eight out of ten patients have at least one episode of HPV infection in their lifetime, there is a need for a method of early detection of genital HPV infection. Cervical cancer is the second type of diagnosed cancer in the rank of genital cancers and the third leading cause of cancer death among the female population. In Romania, the frequency of cervical cancer and mortality caused by this type of cancer remains high. In 2018 Globocan, it was mentioned that the occurrence of cervical cancer in Romania was 8.6%, and the mortality was 19.5/10,000 women. Worldwide, the following have been implemented: primary prevention programmes (via immunization) and secondary prevention programmes – traditional cytological testing, to which co-tests have been added. In the co-testing sector, there has been found with an updated visa – the self-harvesting test, being considered a complementary and innovative method in genital HPV testing, which aims to: identify the presence of highly oncogenic HPV strains with a marked sensitivity. Self-harvesting testing aims to: signal the presence of highly oncogenic strains, extrapolation can lead to early identification of the number of cases of precancerous lesions of the cervix and implicitly of cervical cancer.
{"title":"Complementary and Innovative Method in Genital HPV Testing for Cervical Cancer Prevention","authors":"Georgeta Gînfălean","doi":"10.2478/amtsb-2020-0073","DOIUrl":"https://doi.org/10.2478/amtsb-2020-0073","url":null,"abstract":"Abstract Considering actual SARS-COV 2 pandemic, the comfort and time of the female patient’ trend is to minimize the time spent in the doctor’s office, so that auto-testing is a solving problem in this context. This paper aims at the importance of self-collected urine and vaginal samples, since actual studies are showing that is a complementary method in HPV-testing and a screening method for prevention of cervical cancer. Genital HPV infection is responsible for approximately 99% of cervical cancers, and is considered a sexually transmitted disease. Given that eight out of ten patients have at least one episode of HPV infection in their lifetime, there is a need for a method of early detection of genital HPV infection. Cervical cancer is the second type of diagnosed cancer in the rank of genital cancers and the third leading cause of cancer death among the female population. In Romania, the frequency of cervical cancer and mortality caused by this type of cancer remains high. In 2018 Globocan, it was mentioned that the occurrence of cervical cancer in Romania was 8.6%, and the mortality was 19.5/10,000 women. Worldwide, the following have been implemented: primary prevention programmes (via immunization) and secondary prevention programmes – traditional cytological testing, to which co-tests have been added. In the co-testing sector, there has been found with an updated visa – the self-harvesting test, being considered a complementary and innovative method in genital HPV testing, which aims to: identify the presence of highly oncogenic HPV strains with a marked sensitivity. Self-harvesting testing aims to: signal the presence of highly oncogenic strains, extrapolation can lead to early identification of the number of cases of precancerous lesions of the cervix and implicitly of cervical cancer.","PeriodicalId":7091,"journal":{"name":"Acta Medica Transilvanica","volume":"25 1","pages":"54 - 56"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45605495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Atopic dermatitis (AD) is a chronic inflammatory disease characterized by skin dryness, pruritus and eczematous lesions with various periods of relapse. Symptomatology can appear in childhood and can persist in adulthood. Chronic treatment is required with corticosteroids being the standard options. The side effects of this type of long-term treatment represent a major concern for the pediatric patients. This review aims to give an update of the options used for treatment, apart from the systemic corticosteroids. Mild-to-moderate AD had a good response to creams containing fig and oatmeal extracts and inhibitors of phosphodiesterase-4 (crisaborole). In cases of severe AD, future treatment options could include monoclonal antibodies such as omalizumab and dupilumab
{"title":"Pediatric Atopic Dermatitis: Update on the Treatment Options","authors":"C. Zah, Andreea Emiliana Toporău, Paul Grama","doi":"10.2478/amtsb-2020-0075","DOIUrl":"https://doi.org/10.2478/amtsb-2020-0075","url":null,"abstract":"Abstract Atopic dermatitis (AD) is a chronic inflammatory disease characterized by skin dryness, pruritus and eczematous lesions with various periods of relapse. Symptomatology can appear in childhood and can persist in adulthood. Chronic treatment is required with corticosteroids being the standard options. The side effects of this type of long-term treatment represent a major concern for the pediatric patients. This review aims to give an update of the options used for treatment, apart from the systemic corticosteroids. Mild-to-moderate AD had a good response to creams containing fig and oatmeal extracts and inhibitors of phosphodiesterase-4 (crisaborole). In cases of severe AD, future treatment options could include monoclonal antibodies such as omalizumab and dupilumab","PeriodicalId":7091,"journal":{"name":"Acta Medica Transilvanica","volume":"25 1","pages":"60 - 62"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41569851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Syphilis is a systemic infection caused by Treponema Pallidum spirochete, which is considered to be the main sexually transmitted disease. The genital ulcerations and local inflammation found in syphilis are favouring factors involved in transmitting the HIV infection. Recent data suggests that individuals suffering from other sexually transmitted diseases are 3 to 5 times more exposed to developing HIV infection. On the other hand, simultaneous HIV infection may worsen the syphilis evolution. In the light of this data we present the case of a patient with syphilis-HIV coinfection recently diagnosed and we will summarize the clinical and evolutive features of the syphilis-HIV coinfection.
{"title":"Clinical and Evolutive Features in Syphilis - HIV Coinfection","authors":"G. Iancu, Liliana Elena Todan, M. Rotaru","doi":"10.2478/amtsb-2020-0060","DOIUrl":"https://doi.org/10.2478/amtsb-2020-0060","url":null,"abstract":"Abstract Syphilis is a systemic infection caused by Treponema Pallidum spirochete, which is considered to be the main sexually transmitted disease. The genital ulcerations and local inflammation found in syphilis are favouring factors involved in transmitting the HIV infection. Recent data suggests that individuals suffering from other sexually transmitted diseases are 3 to 5 times more exposed to developing HIV infection. On the other hand, simultaneous HIV infection may worsen the syphilis evolution. In the light of this data we present the case of a patient with syphilis-HIV coinfection recently diagnosed and we will summarize the clinical and evolutive features of the syphilis-HIV coinfection.","PeriodicalId":7091,"journal":{"name":"Acta Medica Transilvanica","volume":"25 1","pages":"12 - 15"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42007760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract The paper is a retrospective clinical-statistical study on patients diagnosed with pathologies that associate transmission hearing loss in order to obtain data on the etiological considerations of transmission hearing loss, its frequency and predisposition.
{"title":"Etiological Considerations Regarding Transmission Hearing Loss","authors":"Mihaela Chialda","doi":"10.2478/amtsb-2020-0062","DOIUrl":"https://doi.org/10.2478/amtsb-2020-0062","url":null,"abstract":"Abstract The paper is a retrospective clinical-statistical study on patients diagnosed with pathologies that associate transmission hearing loss in order to obtain data on the etiological considerations of transmission hearing loss, its frequency and predisposition.","PeriodicalId":7091,"journal":{"name":"Acta Medica Transilvanica","volume":"25 1","pages":"19 - 21"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42598459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Burlibașa, M. Perieanu, Claudia-Camelia Burcea, R. Costea, V. Perieanu, C. Ionescu, Iuliana Babiuc, ioana-Cristina neagoe, Raluca Costea, A. Mihai, M. Dina, M. Malița, G. Tanase, E. Marcov, M. Chirilă
Abstract The Specialization Institute in Dentistry (Dental Clinic), both the one that operated in Colțea Hospital and especially the one that operated in Colentina Hospital, both in Bucharest, the capital of Romania, were the first such higher education units in dentistry from Romania, they are in fact the vanguard of the future faculties of dentistry established in our country according to the Soviet model, in 1948. Thus, in this material we tried to highlight some of the most important moments in the existence of those reference units of dental education, period 1928-1948.
{"title":"The Specialization Institute in Dentistry from Bucharest: 1928-1948","authors":"M. Burlibașa, M. Perieanu, Claudia-Camelia Burcea, R. Costea, V. Perieanu, C. Ionescu, Iuliana Babiuc, ioana-Cristina neagoe, Raluca Costea, A. Mihai, M. Dina, M. Malița, G. Tanase, E. Marcov, M. Chirilă","doi":"10.2478/amtsb-2020-0079","DOIUrl":"https://doi.org/10.2478/amtsb-2020-0079","url":null,"abstract":"Abstract The Specialization Institute in Dentistry (Dental Clinic), both the one that operated in Colțea Hospital and especially the one that operated in Colentina Hospital, both in Bucharest, the capital of Romania, were the first such higher education units in dentistry from Romania, they are in fact the vanguard of the future faculties of dentistry established in our country according to the Soviet model, in 1948. Thus, in this material we tried to highlight some of the most important moments in the existence of those reference units of dental education, period 1928-1948.","PeriodicalId":7091,"journal":{"name":"Acta Medica Transilvanica","volume":"25 1","pages":"73 - 76"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48989865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Particular onset of Sars-Cov-2 infection, by acute mastoiditis without symptoms specific to the case definition. Mastoiditis is part of inflammatory diseases of the middle ear and is important because of its frequency and life-threatening complications due to the close relationship between the middle ear and the cranial cavity. An acute middle ear inflammation may follow a serious course even if the tympanic membrane does not perforate. In the pathogenesis of acute suppurations of the middle ear, the Eustachian tube plays a major role in the appearance of inflammation and the development of the disease. The most common germ can be - a virus whose initial effect is congestion of mucosa and reduce resistance to biological defence by promoting rapid superinfection with Hemophilus Pneumococcus, Staphylococcus, and others. Sars-Cov-2 infection begins with respiratory phenomena and clinical and biological inflammatory syndrome. This article presents a case of Sars-Cov-2 infection with atypical onset of acute mastoiditis. The clinical importance lies in the fact that the virus can migrate from the nose and nasopharynx through its Eustachian tube into the middle ear and from here to the mastoid. The presence of the virus in the middle ear is almost constant even if the patient is asymptomatic. This requires precautions in all surgical maneuvers at this level in patients with Sars-Cov-2 infection.
{"title":"Acute Mastoiditis - Beginning of COVID-19 Infection - Case Report","authors":"Mihaela Chialda","doi":"10.2478/amtsb-2020-0064","DOIUrl":"https://doi.org/10.2478/amtsb-2020-0064","url":null,"abstract":"Abstract Particular onset of Sars-Cov-2 infection, by acute mastoiditis without symptoms specific to the case definition. Mastoiditis is part of inflammatory diseases of the middle ear and is important because of its frequency and life-threatening complications due to the close relationship between the middle ear and the cranial cavity. An acute middle ear inflammation may follow a serious course even if the tympanic membrane does not perforate. In the pathogenesis of acute suppurations of the middle ear, the Eustachian tube plays a major role in the appearance of inflammation and the development of the disease. The most common germ can be - a virus whose initial effect is congestion of mucosa and reduce resistance to biological defence by promoting rapid superinfection with Hemophilus Pneumococcus, Staphylococcus, and others. Sars-Cov-2 infection begins with respiratory phenomena and clinical and biological inflammatory syndrome. This article presents a case of Sars-Cov-2 infection with atypical onset of acute mastoiditis. The clinical importance lies in the fact that the virus can migrate from the nose and nasopharynx through its Eustachian tube into the middle ear and from here to the mastoid. The presence of the virus in the middle ear is almost constant even if the patient is asymptomatic. This requires precautions in all surgical maneuvers at this level in patients with Sars-Cov-2 infection.","PeriodicalId":7091,"journal":{"name":"Acta Medica Transilvanica","volume":"25 1","pages":"25 - 27"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47474385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract The portal vein thrombosis (PVT) is one of the most frequent vascular diseases of the liver, with a high rate of morbidity and mortality. The most common causes of the PVT are hepatic cirrhosis, hepatobiliary neoplasms, inflammatory and infectious abdominal diseases, and myeloproliferative syndromes.(1,2) The natural progress of the PVT has as a result portal hypertension which leads to splenomegaly and the formation of portosystemic collateral vessels, as well as gastroesophageal, duodenal and jejunal varices. Ultrasonography, especially Doppler ultrasound, is the most widely used imaging method to asses, supervise and diagnose PVT in patients with hepatopathies. The purpose of acute PVT treatment is to re-permeabilize the obstructed vessels; the endoscopic ligature of the varices in the eventuality of their rupture is safe and extremely efficient in chronic PVT. To conclude, PVT is the most common hepatic vascular disorder, and its prevalence has increased particularly among the patients with chronic hepatopathies.(3)
{"title":"Risk Factors Regarding Portal Vein Thrombosis in Chronic Liver Disease","authors":"Liliana Vecerzan, R. Mihăilă","doi":"10.2478/amtsb-2020-0068","DOIUrl":"https://doi.org/10.2478/amtsb-2020-0068","url":null,"abstract":"Abstract The portal vein thrombosis (PVT) is one of the most frequent vascular diseases of the liver, with a high rate of morbidity and mortality. The most common causes of the PVT are hepatic cirrhosis, hepatobiliary neoplasms, inflammatory and infectious abdominal diseases, and myeloproliferative syndromes.(1,2) The natural progress of the PVT has as a result portal hypertension which leads to splenomegaly and the formation of portosystemic collateral vessels, as well as gastroesophageal, duodenal and jejunal varices. Ultrasonography, especially Doppler ultrasound, is the most widely used imaging method to asses, supervise and diagnose PVT in patients with hepatopathies. The purpose of acute PVT treatment is to re-permeabilize the obstructed vessels; the endoscopic ligature of the varices in the eventuality of their rupture is safe and extremely efficient in chronic PVT. To conclude, PVT is the most common hepatic vascular disorder, and its prevalence has increased particularly among the patients with chronic hepatopathies.(3)","PeriodicalId":7091,"journal":{"name":"Acta Medica Transilvanica","volume":"25 1","pages":"38 - 41"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44175074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Kawasaki disease is a rare condition that mainly affects children younger than 6 years old. However, it represents the most common cause of acquired heart disease and the second most frequent vasculitis in children. Its importance consists in cardiac (coronary) complications identified in adults younger than 40 years old. Early diagnosis is pivotal for preventing (or reducing) coronary aneurysms and avoiding, at least, later unnecessary surgical interventions. Full (classic, complete) Kawasaki disease is easily diagnosed, even if the symptoms are not always present at the same time and most of them are unspecific. Incomplete Kawasaki disease implies challenge, delay or misdiagnosis. “Picking it up early is a winner” – the specialists say, so that early treatment administered at the right moment can stop the inflammatory process leading to much better outcomes, consequently.
{"title":"Incomplete Kawasaki Disease: What Can We Do About It?","authors":"L. Dobrotă, C. Cazan, D. Bratu, B. Neamțu","doi":"10.2478/amtsb-2020-0074","DOIUrl":"https://doi.org/10.2478/amtsb-2020-0074","url":null,"abstract":"Abstract Kawasaki disease is a rare condition that mainly affects children younger than 6 years old. However, it represents the most common cause of acquired heart disease and the second most frequent vasculitis in children. Its importance consists in cardiac (coronary) complications identified in adults younger than 40 years old. Early diagnosis is pivotal for preventing (or reducing) coronary aneurysms and avoiding, at least, later unnecessary surgical interventions. Full (classic, complete) Kawasaki disease is easily diagnosed, even if the symptoms are not always present at the same time and most of them are unspecific. Incomplete Kawasaki disease implies challenge, delay or misdiagnosis. “Picking it up early is a winner” – the specialists say, so that early treatment administered at the right moment can stop the inflammatory process leading to much better outcomes, consequently.","PeriodicalId":7091,"journal":{"name":"Acta Medica Transilvanica","volume":"25 1","pages":"57 - 59"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42807784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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