Splenic microenvironments are suitable for the definition of immunologic processes, which may different than other non lymphoid organs. Splenic changes have been identified after Leishmania and viral infections, but after bacterial need more study. In kidney, as a non lymphoid organ, the bacterial infection associated with acute kidney injury. Acute kidney injury can lead to chronic kidney disease which can lead to kidney failure. The present work amid to study the differences between bacterial infection stages in lymphoid organ, spleen, and nonlymphoid organ, kidney; and the effect of bacterial infection stage on the renal function. 20 males Balb/c mice were used in this study, aged about 2 months and weight about 24g. 15 mice were injected intraperitoneal with 200μl E.coli, isolated from children have urinary infection, in final concentration (10cell /ml), and 5 mice were injected with only normal saline as control group. The mice were killed in different time after E.coli injection: 24, 48, and 72h. Blood was collected and used in serum creatinine and blood urea determinations. Spleen and kidney were collected, fixed in 10% formalin solution, and processed by standard procedures. The body weights were recorded before sacrifice. The results showed that: significantly higher body weight in infected groups within 24, 48, and 72h compared to zero time and control group, significantly negative correlations between body weight and infection duration, white pulp widening, back off red pulp 10 Saad A. AL-Jashaami et al. size, and activation of germinal center with the time after bacterial injection, infiltration of inflammatory cells and appearing of the focal necrosis of renal epithelial tubules within 48h after bacterial infection and increased after 72h, significantly higher serum creatinine (S.Cr) and blood urea (B.Urea) in the infected groups within 48 and 72h after bacterial injection compared to control group, and significantly positive correlations between S.Cr and B.Urea levels in infected groups and all groups together but not in the control group.
脾微环境适合于免疫过程的定义,这可能不同于其他非淋巴器官。利什曼原虫和病毒感染后已发现脾脏改变,但细菌感染后需要更多的研究。肾脏作为非淋巴器官,细菌感染可引起急性肾损伤。急性肾损伤可导致慢性肾病,慢性肾病可导致肾衰竭。本研究旨在探讨细菌感染在淋巴器官、脾脏和非淋巴器官、肾脏的分期差异;以及细菌感染阶段对肾功能的影响。本研究选用雄性Balb/c小鼠20只,年龄约2月龄,体重约24g。15只小鼠腹腔注射终浓度为200μl(10细胞/ml)的尿路感染患儿分离大肠杆菌,5只小鼠腹腔注射生理盐水作为对照组。注射大肠杆菌后,小鼠分别在24、48、72h的不同时间死亡。采集血液用于测定血清肌酐和血尿素。取脾、肾,用10%福尔马林溶液固定,按标准程序处理。献祭前记录体重。结果表明:感染组在24、48和72h内的体重明显高于零时间组和对照组,体重与感染持续时间、白牙髓扩大、退红牙髓10 Saad A. AL-Jashaami等人的大小、生发中心的激活与注射细菌后的时间呈显著负相关。感染组在细菌注射后48h和72h内血清肌酐(S.Cr)和血尿素(B.Urea)均显著高于对照组,感染组和各组间S.Cr和B.Urea水平呈显著正相关,对照组间无显著正相关。
{"title":"The differences in inflammation changes between lymphoid and non lymphoid tissues of mice after i.p. E.coli injection and its effect on renal function","authors":"Saad A. AL-Jashaami, Noori M. Lauibi, J. Jouda","doi":"10.12988/ASB.2017.61039","DOIUrl":"https://doi.org/10.12988/ASB.2017.61039","url":null,"abstract":"Splenic microenvironments are suitable for the definition of immunologic processes, which may different than other non lymphoid organs. Splenic changes have been identified after Leishmania and viral infections, but after bacterial need more study. In kidney, as a non lymphoid organ, the bacterial infection associated with acute kidney injury. Acute kidney injury can lead to chronic kidney disease which can lead to kidney failure. The present work amid to study the differences between bacterial infection stages in lymphoid organ, spleen, and nonlymphoid organ, kidney; and the effect of bacterial infection stage on the renal function. 20 males Balb/c mice were used in this study, aged about 2 months and weight about 24g. 15 mice were injected intraperitoneal with 200μl E.coli, isolated from children have urinary infection, in final concentration (10cell /ml), and 5 mice were injected with only normal saline as control group. The mice were killed in different time after E.coli injection: 24, 48, and 72h. Blood was collected and used in serum creatinine and blood urea determinations. Spleen and kidney were collected, fixed in 10% formalin solution, and processed by standard procedures. The body weights were recorded before sacrifice. The results showed that: significantly higher body weight in infected groups within 24, 48, and 72h compared to zero time and control group, significantly negative correlations between body weight and infection duration, white pulp widening, back off red pulp 10 Saad A. AL-Jashaami et al. size, and activation of germinal center with the time after bacterial injection, infiltration of inflammatory cells and appearing of the focal necrosis of renal epithelial tubules within 48h after bacterial infection and increased after 72h, significantly higher serum creatinine (S.Cr) and blood urea (B.Urea) in the infected groups within 48 and 72h after bacterial injection compared to control group, and significantly positive correlations between S.Cr and B.Urea levels in infected groups and all groups together but not in the control group.","PeriodicalId":7194,"journal":{"name":"Advanced Studies in Biology","volume":"6 1","pages":"9-19"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79646805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purification of polluted air from volatile organic compounds by means of biologic methods has been considered due to great advantages. Biofiltration is one of the best biologic methods for doing such processes. In this research, a mathematical model has been presented in order for Biofiltration process of polluted air in which limiter effects of oxygen and humidity have been considered. Since, microbe’s inclination to substrate and microbial growth and production output of biomass are effective on bio filter’s performance, evaluating the effect of these quantities is necessary. Dynamic modeling of Biofiltration process of polluted air in stable and unstable conditions was conducted by emphasizing on humidity in the equations of mass transfer and sensitivity analysis in order for determining change effect of this parameter on the performance of model. The results show that the maximum amount of special growth results in the increase of absorption capacity, and also the model rightly confirms that constant increase of saturation 114 Morteza Kashefi Asl et al. reduces the absorption capacity; whilst by means of this model, we can show that special surface switch and thickness change of biofilm are effective on absorption capacity.
{"title":"Dynamic modeling process from the hexane removal of contaminated air bio filtration method","authors":"M. K. Asl, M. Sohrabi, S. Yaghoubi","doi":"10.12988/asb.2017.724","DOIUrl":"https://doi.org/10.12988/asb.2017.724","url":null,"abstract":"Purification of polluted air from volatile organic compounds by means of biologic methods has been considered due to great advantages. Biofiltration is one of the best biologic methods for doing such processes. In this research, a mathematical model has been presented in order for Biofiltration process of polluted air in which limiter effects of oxygen and humidity have been considered. Since, microbe’s inclination to substrate and microbial growth and production output of biomass are effective on bio filter’s performance, evaluating the effect of these quantities is necessary. Dynamic modeling of Biofiltration process of polluted air in stable and unstable conditions was conducted by emphasizing on humidity in the equations of mass transfer and sensitivity analysis in order for determining change effect of this parameter on the performance of model. The results show that the maximum amount of special growth results in the increase of absorption capacity, and also the model rightly confirms that constant increase of saturation 114 Morteza Kashefi Asl et al. reduces the absorption capacity; whilst by means of this model, we can show that special surface switch and thickness change of biofilm are effective on absorption capacity.","PeriodicalId":7194,"journal":{"name":"Advanced Studies in Biology","volume":"88 1","pages":"113-135"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80289157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Goodarzi, A. Saedisomeolia, E. F. Moghadam, Ali Sadoogh-Abbasi, A. Sianaki, Zahra Seaf
Introduction: New findings suggest that gallbladder not only plays a role in control of concentration and storage of the bile acids, but also, may be effective on nutrients metabolism, in particular on fat metabolism. Objective: This study aimed to determine the effects of cholecystectomy on serum lipid parameters. Materials and methods: This cross-sectional study was conducted on seventy patients who were undergoing cholecystectomy. The serum concentration of lipoproteins, weight, BMI, and dietary intake of subjects were assessed before and one month after the cholecystectomy operation. Results: No significant difference was found regarding serum concentration of triglycerides, total cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) to LDL proportion, while, HDL concentration represented a significant reduction after the cholecystectomy. No significant difference was observed in terms of the dietary intake of energy, fat, protein, carbohydrate, fiber, saturated and unsaturated fat before and after the surgery. Conclusion: We showed that cholecystectomy decreases the HDL-C by the day of 30 after surgery, however, other biomarkers such as lipoproteins, weight, and BMI, did not differ significantly.Besides, the stability of the serum levels of lipoproteins preand post-cholecystectomy may be due to the insignificant changes in factors related to diet.
{"title":"Evaluation of the serum lipid profile and dietary intake in patients undergoing cholecystectomy","authors":"R. Goodarzi, A. Saedisomeolia, E. F. Moghadam, Ali Sadoogh-Abbasi, A. Sianaki, Zahra Seaf","doi":"10.12988/ASB.2017.61140","DOIUrl":"https://doi.org/10.12988/ASB.2017.61140","url":null,"abstract":"Introduction: New findings suggest that gallbladder not only plays a role in control of concentration and storage of the bile acids, but also, may be effective on nutrients metabolism, in particular on fat metabolism. Objective: This study aimed to determine the effects of cholecystectomy on serum lipid parameters. Materials and methods: This cross-sectional study was conducted on seventy patients who were undergoing cholecystectomy. The serum concentration of lipoproteins, weight, BMI, and dietary intake of subjects were assessed before and one month after the cholecystectomy operation. Results: No significant difference was found regarding serum concentration of triglycerides, total cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) to LDL proportion, while, HDL concentration represented a significant reduction after the cholecystectomy. No significant difference was observed in terms of the dietary intake of energy, fat, protein, carbohydrate, fiber, saturated and unsaturated fat before and after the surgery. Conclusion: We showed that cholecystectomy decreases the HDL-C by the day of 30 after surgery, however, other biomarkers such as lipoproteins, weight, and BMI, did not differ significantly.Besides, the stability of the serum levels of lipoproteins preand post-cholecystectomy may be due to the insignificant changes in factors related to diet.","PeriodicalId":7194,"journal":{"name":"Advanced Studies in Biology","volume":"5 1","pages":"171-179"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83387571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Among smokers, often the desire to quit smoking arise. A large number of smokers attempt to quit, but only a fraction of them are successful. While the health and monetary benefits are inarguable. The huge amount of stress associated with smoking, a combination of powerful cravings, sleep and mood disturbances and cognitive changes often stymie even the most motivated of individuals. In this paper, a mathematical model is proposed and analyzed in which the temporary quitters turn back to smoking by powerful cravings for smoking. We have discussed the qualitative behavior of the model and numerical simulations are carried out to support the analytical results.
{"title":"Smoking model with cravings to smoke","authors":"A. Awan, Attia Sharif, T. Hussain, M. Ozair","doi":"10.12988/ASB.2017.61245","DOIUrl":"https://doi.org/10.12988/ASB.2017.61245","url":null,"abstract":"Among smokers, often the desire to quit smoking arise. A large number of smokers attempt to quit, but only a fraction of them are successful. While the health and monetary benefits are inarguable. The huge amount of stress associated with smoking, a combination of powerful cravings, sleep and mood disturbances and cognitive changes often stymie even the most motivated of individuals. In this paper, a mathematical model is proposed and analyzed in which the temporary quitters turn back to smoking by powerful cravings for smoking. We have discussed the qualitative behavior of the model and numerical simulations are carried out to support the analytical results.","PeriodicalId":7194,"journal":{"name":"Advanced Studies in Biology","volume":"128 1","pages":"31-41"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88107474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shima Bayat, M. Ataei, S. Nabavi, Mojgan Ghahari, M. Sanati
{"title":"Expression alternations of CCR5 in new case and treated patients with multiple sclerosis","authors":"Shima Bayat, M. Ataei, S. Nabavi, Mojgan Ghahari, M. Sanati","doi":"10.12988/ASB.2017.7411","DOIUrl":"https://doi.org/10.12988/ASB.2017.7411","url":null,"abstract":"","PeriodicalId":7194,"journal":{"name":"Advanced Studies in Biology","volume":"65 1","pages":"193-204"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80013433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Forest is a natural element that can absorb CO2 in large quantities. This is due to the existing vegetation in the forests bind CO2 while the process of photosynthesis and store it in the form of biomass. So that, the existence of forests affect the prevention and handling of global warming on earth. This research aims to measure the biomass density and carbon stock of tropical community forests area at Sumberdodol and Tapak Villages of FMU (Forest Managemen Unit) Lawu Manunggal – Panekan – Magetan District. The research method for inventory of individual trees in forest stands uses finger circle plot of 0.05 Ha. Its intensity is 5%. Destructive Biomass Measurements while analyzing carbon stock uses titration method of Wallky and Black. Result of research Biomass density of forests are Melia 61,288,649 kg/Ha, Mahogany 97,472,875 kg/Ha, Teak 88,925,376 kg/Ha, and Albicia 25,566,573 kg/ Ha. FMU Lawu Manunggal forest 206 Ahadiati Rohmatiah et al. area at Sumberdodol and Tapak is 276,33 Ha. Total Biomass density of Melia 1,225.77 tons, Mahogany 2,216.47 tons, Teak 1,778.51 tons, and albicia 511.33 tons. Total forest stands are 5,732.08 tons. The carbon stock average of Melia 28,806 ton/Ha, Mahogany 45,812 ton/Ha, Teak type 41,795 ton/Ha, and Albicia 12,016 ton/Ha. The total Carbon stock of Sumberdodol and Tapak Villages are 2,694.08 tons.
{"title":"Biomass density and carbon stock of tropical community forest area at FMU Lawu Manunggal-Panekan-Magetan district","authors":"Ahadiati Rohmatiah, Lyya Supriono, M. Lukito","doi":"10.12988/asb.2017.7924","DOIUrl":"https://doi.org/10.12988/asb.2017.7924","url":null,"abstract":"Forest is a natural element that can absorb CO2 in large quantities. This is due to the existing vegetation in the forests bind CO2 while the process of photosynthesis and store it in the form of biomass. So that, the existence of forests affect the prevention and handling of global warming on earth. This research aims to measure the biomass density and carbon stock of tropical community forests area at Sumberdodol and Tapak Villages of FMU (Forest Managemen Unit) Lawu Manunggal – Panekan – Magetan District. The research method for inventory of individual trees in forest stands uses finger circle plot of 0.05 Ha. Its intensity is 5%. Destructive Biomass Measurements while analyzing carbon stock uses titration method of Wallky and Black. Result of research Biomass density of forests are Melia 61,288,649 kg/Ha, Mahogany 97,472,875 kg/Ha, Teak 88,925,376 kg/Ha, and Albicia 25,566,573 kg/ Ha. FMU Lawu Manunggal forest 206 Ahadiati Rohmatiah et al. area at Sumberdodol and Tapak is 276,33 Ha. Total Biomass density of Melia 1,225.77 tons, Mahogany 2,216.47 tons, Teak 1,778.51 tons, and albicia 511.33 tons. Total forest stands are 5,732.08 tons. The carbon stock average of Melia 28,806 ton/Ha, Mahogany 45,812 ton/Ha, Teak type 41,795 ton/Ha, and Albicia 12,016 ton/Ha. The total Carbon stock of Sumberdodol and Tapak Villages are 2,694.08 tons.","PeriodicalId":7194,"journal":{"name":"Advanced Studies in Biology","volume":"4 1","pages":"205-216"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83645525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
One of the characteristics of human is the ability to change behavior based on previous experience and learning is the gaining the information that makes it possible. Memory is somewhere the preserve and storing this information. The hippocampus is one of centers in the brain responsible for learning and this center is a part of limbic system where new neurons are generated through neurogenesis. The aim of this study was to assess the changes in neuronal density in CA1 and CA2 regions in hippocampus of rats born from mothers fed by Cantharellus cibarius extract. In this experimental study, 24 female Wistar rats weighing 200 250 g were randomly divided to randomize controlled and 1, 2 and 3 treated groups with Cantharellus cibarius hydroalcoholic extract with doses of 100, 250 and 500. Treatment was performed through gavage method 7 days before mating. After delivery, one newborn rat of each mother was accidentally selected and anesthetized with ether, and after removing the skull, tissue processing was per182 Zahra Esmaili and Maryam Tehranipour formed in order to study the neuronal density in CA1 and CA2 areas by stereology and dissector methods, and all findings were compared by using ANOVA and t-test at significance level, (p<0.05).In control and 1, 2 and 3 experimental groups, the mean of neuronal density of CA1 was 2423 ±1.59, 3425±183, 4003 ± 101 and 4822 ±19.5, respectively, in CA2 area it was 2066±390, 3568±150, 3993 ±65.05 and 4629 ±64.7. Statistical analysis showed significant increase in neuronal density in (CA1, CA2) areas in experimental group (doses of 100, 250 and 500 mg / kg hydroalcoholic extract) compared to the control group, (p<0.05). It is possible that the Cantharellus cibarius extract increases the neurogenesis by excess neuronal density due to minerals such as magnesium, calcium, zinc, vitamin D and vitamin E.
{"title":"The assessment of neuronal density of CA1 and CA2 regions in hippocampus of newborn rats born from mothers fed by Cantharellus cibarius hidroalcoholic extract","authors":"Z. Esmaili, M. Tehranipour","doi":"10.12988/ASB.2017.7521","DOIUrl":"https://doi.org/10.12988/ASB.2017.7521","url":null,"abstract":"One of the characteristics of human is the ability to change behavior based on previous experience and learning is the gaining the information that makes it possible. Memory is somewhere the preserve and storing this information. The hippocampus is one of centers in the brain responsible for learning and this center is a part of limbic system where new neurons are generated through neurogenesis. The aim of this study was to assess the changes in neuronal density in CA1 and CA2 regions in hippocampus of rats born from mothers fed by Cantharellus cibarius extract. In this experimental study, 24 female Wistar rats weighing 200 250 g were randomly divided to randomize controlled and 1, 2 and 3 treated groups with Cantharellus cibarius hydroalcoholic extract with doses of 100, 250 and 500. Treatment was performed through gavage method 7 days before mating. After delivery, one newborn rat of each mother was accidentally selected and anesthetized with ether, and after removing the skull, tissue processing was per182 Zahra Esmaili and Maryam Tehranipour formed in order to study the neuronal density in CA1 and CA2 areas by stereology and dissector methods, and all findings were compared by using ANOVA and t-test at significance level, (p<0.05).In control and 1, 2 and 3 experimental groups, the mean of neuronal density of CA1 was 2423 ±1.59, 3425±183, 4003 ± 101 and 4822 ±19.5, respectively, in CA2 area it was 2066±390, 3568±150, 3993 ±65.05 and 4629 ±64.7. Statistical analysis showed significant increase in neuronal density in (CA1, CA2) areas in experimental group (doses of 100, 250 and 500 mg / kg hydroalcoholic extract) compared to the control group, (p<0.05). It is possible that the Cantharellus cibarius extract increases the neurogenesis by excess neuronal density due to minerals such as magnesium, calcium, zinc, vitamin D and vitamin E.","PeriodicalId":7194,"journal":{"name":"Advanced Studies in Biology","volume":"24 1","pages":"181-191"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79418872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Timing of events in many cellular processes, such as cell-cycle control, cell differentiation, and so on, depend on regulatory proteins reaching critical threshold levels. The time at which special protein cross up the threshold levels is called as the first-passage time(FPT). Here, we theoretically show that geometric conditional burst has unneglectable effects on gene expression and FPT. More precisely, if the mean of protein is fixed and the same burst size, conditional geometric burst increase the mean and noise of FPT compared with the geometric distribution. If the mean of FPT is fixed and the same burst size, conditional geometric burst increase noise of FPT compared with the geometric distribution.
{"title":"Effects of different burst form on gene expression dynamic and first-passage time","authors":"Xuejie Liu, Qiuying Li","doi":"10.12988/asb.2017.726","DOIUrl":"https://doi.org/10.12988/asb.2017.726","url":null,"abstract":"Timing of events in many cellular processes, such as cell-cycle control, cell differentiation, and so on, depend on regulatory proteins reaching critical threshold levels. The time at which special protein cross up the threshold levels is called as the first-passage time(FPT). Here, we theoretically show that geometric conditional burst has unneglectable effects on gene expression and FPT. More precisely, if the mean of protein is fixed and the same burst size, conditional geometric burst increase the mean and noise of FPT compared with the geometric distribution. If the mean of FPT is fixed and the same burst size, conditional geometric burst increase noise of FPT compared with the geometric distribution.","PeriodicalId":7194,"journal":{"name":"Advanced Studies in Biology","volume":"50 1","pages":"91-100"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73688075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Having a healthy child is the dream of every couple, and the child's gender for many couples is very important. The effect of nutrition on gender in several studies evaluated and is one of the most popular methods which today, as the common form is recommended for embryo selection. The aim of this study was to investigate Cantharellus Cibarius hydroalcoholic extracts on fertility and sexing in rats. Twenty four wistar rats(female)with weighing approximately 200-250 grams were randomly divided into four groups, including control and treatment groups with the above mentioned mushroom hydroalcoholic extract (with doses of 100, 250 and 500 mg/ kg). The Cantharellus Cibarius extract were fed to rats in by gavage method seven consecutive days and then each rat in a separate cage in adjacent to the male of the same breed were mated, after 19-21 days of pregnancy, newborns being counting and sexing. Quantitative data analysis using the software minitab and by ANOVA and t-test was performed. According to the findings, the number of births in the treatment groups compared to the control group 54 Asiye Karimi et al. there is no significant difference, but in the sexing, the female set in treatment groups compared to the control group showed a significant difference (p<0.05) that increase in the treated groups with doses of 500 was higher. As a result, increase of gynogenesis in treated groups with the extract of the mushroom Cantharellus Cibarius is probably due to calcium and magnesium ions.
{"title":"The effect of Cantharellus Cibarius hidroalcoholic extract on fertility and sex determination in rats","authors":"A. Karimi, M. Tehranipour, Mahmud Zokaei","doi":"10.12988/ASB.2017.61244","DOIUrl":"https://doi.org/10.12988/ASB.2017.61244","url":null,"abstract":"Having a healthy child is the dream of every couple, and the child's gender for many couples is very important. The effect of nutrition on gender in several studies evaluated and is one of the most popular methods which today, as the common form is recommended for embryo selection. The aim of this study was to investigate Cantharellus Cibarius hydroalcoholic extracts on fertility and sexing in rats. Twenty four wistar rats(female)with weighing approximately 200-250 grams were randomly divided into four groups, including control and treatment groups with the above mentioned mushroom hydroalcoholic extract (with doses of 100, 250 and 500 mg/ kg). The Cantharellus Cibarius extract were fed to rats in by gavage method seven consecutive days and then each rat in a separate cage in adjacent to the male of the same breed were mated, after 19-21 days of pregnancy, newborns being counting and sexing. Quantitative data analysis using the software minitab and by ANOVA and t-test was performed. According to the findings, the number of births in the treatment groups compared to the control group 54 Asiye Karimi et al. there is no significant difference, but in the sexing, the female set in treatment groups compared to the control group showed a significant difference (p<0.05) that increase in the treated groups with doses of 500 was higher. As a result, increase of gynogenesis in treated groups with the extract of the mushroom Cantharellus Cibarius is probably due to calcium and magnesium ions.","PeriodicalId":7194,"journal":{"name":"Advanced Studies in Biology","volume":"38 1","pages":"53-61"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77524867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Touraj Miandoabi, K. H. Tappeh, H. Nahrevanian, Seyed Masoud Kazemi, H. Mohammadzadeh, Haleh Hanifian
The aim of this study was to evaluate antimalarial effects of Iranian flora Artemisia oliveriana on Plasmodium berghei in vivo and photochemistry of its natural effective components. This is the first application of Iranian flora A. oliveriana on murine malaria in Iran. The aerial parts of A. oliveriana were collected at the flowering stage from Qum and Isfahan provinces, in central part of Iran in 2010. The aerial parts were air-dried at room temperature and then powdered and macerated in methanol and filtered and it was extracted and dried by Rotary Evaporator. The toxicity of herbal extract was assessed on four groups of naive NMRI mice and it‘s antimalarial efficacy was investigated on infected P. berghei animals. The significance of differences was determined by student‘s ttest using Graph Pad prism software. The results indicated no toxicity was observed even by high concentration of herbal extract by measuring body weight, survival rate and hepato/ splenomegaly. It is demonstrated that total extract A. oliveriana possesses therapeutic inactivity against P. berghei which indicates its antimalarial effects in vivo on NMRI mice. 44 Touraj Miandoabi et al.
本研究旨在评价伊朗植物橄榄蒿(Artemisia oliveriana)体内抗伯氏疟原虫(Plasmodium berghei)的作用及其天然有效成分的光化学性质。这是伊朗植物A. oliveriana在伊朗首次应用于小鼠疟疾。本研究于2010年在伊朗中部库姆省和伊斯法罕省采集花期空中部分。空气部件在室温下风干,然后在甲醇中粉碎浸渍,过滤后用旋转蒸发器提取干燥。研究了中药提取物对四组NMRI小鼠的毒性作用,并对感染伯氏疟原虫的动物进行了抗疟作用的研究。采用Graph Pad prism软件进行学生检验,确定差异的显著性。结果表明,即使是高浓度的草药提取物也没有毒性,通过测量体重、存活率和肝/脾肿大。结果表明,榄香总提取物对柏氏疟原虫无治疗作用,表明其在NMRI小鼠体内具有抗疟作用。[4]图拉杰。
{"title":"Pharmacochemistry of Iranian flora Artemisia oliveriana and its antimalarial effects on Plasmodium berghei in vivo","authors":"Touraj Miandoabi, K. H. Tappeh, H. Nahrevanian, Seyed Masoud Kazemi, H. Mohammadzadeh, Haleh Hanifian","doi":"10.12988/ASB.2017.61141","DOIUrl":"https://doi.org/10.12988/ASB.2017.61141","url":null,"abstract":"The aim of this study was to evaluate antimalarial effects of Iranian flora Artemisia oliveriana on Plasmodium berghei in vivo and photochemistry of its natural effective components. This is the first application of Iranian flora A. oliveriana on murine malaria in Iran. The aerial parts of A. oliveriana were collected at the flowering stage from Qum and Isfahan provinces, in central part of Iran in 2010. The aerial parts were air-dried at room temperature and then powdered and macerated in methanol and filtered and it was extracted and dried by Rotary Evaporator. The toxicity of herbal extract was assessed on four groups of naive NMRI mice and it‘s antimalarial efficacy was investigated on infected P. berghei animals. The significance of differences was determined by student‘s ttest using Graph Pad prism software. The results indicated no toxicity was observed even by high concentration of herbal extract by measuring body weight, survival rate and hepato/ splenomegaly. It is demonstrated that total extract A. oliveriana possesses therapeutic inactivity against P. berghei which indicates its antimalarial effects in vivo on NMRI mice. 44 Touraj Miandoabi et al.","PeriodicalId":7194,"journal":{"name":"Advanced Studies in Biology","volume":"57 72 1","pages":"43-51"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77689343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}