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Development and validation of the RQC: a daily contact log for ACT and ICM teams RQC的开发和验证:ACT和ICM团队的每日联系日志
Pub Date : 2010-03-01 DOI: 10.1017/S1121189X00001597
A. Lesage, D. Gelinas, J. Bisson, Eric Dion, N. Ricard
Aim – Instruments to measure the process - the daily activities of home care workers - have received little attention and may impede research in refining the active ingredients, the clientele best served and continuous quality improvement. We developed a decade ago in Quebec, Canada, a new daily contact log (relevé quotidien des contacts or RQC) that has now reached in practice 1 million entries. Methods – Three features distinguish the RQC development, namely, practical ergonomics, a clear logic, and response categories easy to understand and retain. The instrument is filled following any 10-minute or more contact with or about the client, and covers the location, time and actors of the episode of care, and the nature of the intervention (crisis, representing, accompanying, discussing) in 10 areas (i.e. medication, daily living activities, housing, relationships, substance abuse, legal, etc.). Inter-rater agreement for each RQC response category and rater agreement with a criterion measure (coded vignettes) were evaluated. Results – Kappa coefficients and intra-class correlation coefficients yielded results ranging from at least moderate to generally substantial agreement for all 77 response categories. Conclusions – The new RQC may support international studies of the implementation and application of various forms of intensive home care, refining its indications, and serves as a clinical and managerial tool to ensure quality of the interventions. Declaration of Interest: The study was financed by funds from the Fonds de la recherche en santé du Québec (FRSQ) and the Canadian Institutes of Health Research (CIHR). The authors have not been involved with any other forms of financing that might be considered a conflict of interest in connection with the submitted article. Declaration of Interest: The study was financed by funds from the Fonds de la recherche en santé du Québec (FRSQ) and the Canadian Institutes of Health Research (CIHR). The authors have not been involved with any other forms of financing that might be considered a conflict of interest in connection with the submitted article.
目的-测量过程的仪器-家庭护理人员的日常活动-很少受到关注,可能妨碍研究提炼有效成分,为客户提供最佳服务和持续质量改进。十年前,我们在加拿大魁北克省开发了一个新的每日联系人日志(relevant quotidien des contacts或RQC),目前已达到100万条记录。方法——区分RQC发展的三个特点,即实用的人机工程学、清晰的逻辑和易于理解和保留的响应类别。在与来访者接触10分钟或更长时间后填写该表格,内容包括发生护理事件的地点、时间和参与者,以及干预的性质(危机、代表、陪伴、讨论),涉及10个领域(即药物治疗、日常生活活动、住房、关系、药物滥用、法律等)。评估每个RQC反应类别的评分者之间的一致性以及评分者与标准测量(编码小片段)的一致性。结果- Kappa系数和类内相关系数对所有77个反应类别产生的结果从至少中等到基本一致。结论-新的RQC可以支持各种形式的家庭重症监护的实施和应用的国际研究,完善其适应症,并作为临床和管理工具,以确保干预的质量。利益声明:这项研究的资金来自于加拿大健康研究所(CIHR)和加拿大健康研究基金会(FRSQ)。作者没有参与任何可能被认为与所提交文章有利益冲突的其他形式的融资。利益声明:这项研究的资金来自于加拿大健康研究所(CIHR)和加拿大健康研究基金会(FRSQ)。作者没有参与任何可能被认为与所提交文章有利益冲突的其他形式的融资。
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引用次数: 3
What is a run-in phase? 什么是磨合阶段?
Pub Date : 2010-03-01 DOI: 10.1017/S1121189X0000155X
A. Cipriani, J. Geddes
Abstract Run-in periods are frequently used when designing a clinical trial. In this paper we analysed the implications of runin periods for interpreting the results of clinical trials and applying these results in clinical practice. Study reports should indicate in details how run-in periods were carried out.
在设计临床试验时,磨合期经常被用到。在本文中,我们分析了运行周期对解释临床试验结果和在临床实践中应用这些结果的影响。研究报告应详细说明磨合期是如何进行的。
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引用次数: 5
EPS volume 19 issue 1 Front matter EPS第19卷第1期
Pub Date : 2010-03-01 DOI: 10.1017/s1121189x00001494
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引用次数: 0
Development of a set of schizophrenia quality indicators for integrated care. 制定一套精神分裂症综合护理质量指标。
Pub Date : 2010-01-01 DOI: 10.1017/s1121189x00001603
Stefan Weinmann, Christiane Roick, Luise Martin, Stefan Willich, Thomas Becker

Aim: We aimed at developing a prioritized set of quality indicators for schizophrenia care to be used for continuous quality monitoring. They should be evidence-based and rely on routine data.

Methods: A systematic literature search was performed to identify papers on validated quality indicators published between 1990 to April 2008 in MEDLINE, the Cochrane databases, EMBASE and PsycINFO. Databases of relevant national and international organizations were searched. Indicators were described with respect to meaningfulness, feasibility and actionability. A workshop with relevant stakeholders evaluated the measures through a structured consensus process.

Results: We identified 78 indicators through literature search and selected 22 quality indicators. Furthermore, 12 structural and case-mix indicators were choosen. Only five quality indicators were rated "essential indicators" (priority 1), 14 were rated "additional first choice" (priority 2), and three were rated as "additional second choice" (priority 3). Only four indicators assessed outcome quality. In the majority of indicators the evidence base supporting the indicator recommendation was weak. None of the selected indicators was validated in experimental studies.

Conclusions: Evidence and validation base played only a subordinate role for indicator prioritisation by stakeholders indicating that there are discrepancies between clinical questions and requirements in schizophrenia care and scientific research.

目的:我们旨在制定一套优先的精神分裂症护理质量指标,用于持续质量监测。它们应该以证据为基础,并依赖于常规数据。方法:系统检索MEDLINE、Cochrane数据库、EMBASE和PsycINFO数据库1990年至2008年4月间发表的关于质量指标的论文。检索了有关国家和国际组织的数据库。介绍了有关意义、可行性和可操作性的指标。与相关利益攸关方举行的研讨会通过结构化的协商一致进程评估了这些措施。结果:通过文献检索,确定了78个质量指标,筛选出22个质量指标。此外,还选择了12个结构性和病例组合指标。只有5个质量指标被评为“基本指标”(优先级1),14个被评为“额外的第一选择”(优先级2),3个被评为“额外的第二选择”(优先级3)。只有4个指标评估结果质量。在大多数指标中,支持指标建议的证据基础薄弱。所选指标均未在实验研究中得到验证。结论:证据和验证基础对利益相关者的指标优先排序仅起从属作用,表明精神分裂症护理和科学研究的临床问题与要求存在差异。
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引用次数: 17
Diagnosing psychotic disorders: validity, reliability and applications of the Diagnostic Interview for Psychosis (DIP). Italian version. 精神障碍诊断:精神病诊断访谈(DIP)的效度、信度及应用。意大利版本。
Pub Date : 2010-01-01
Alberto Rossi, Vera Morgan, Francesco Amaddeo, Marco Sandri, Laura Grigoletti, Francesca Maggioni, Adele Ferro, Elena Rigon, Valeria Donisi, Valeria Vailati Venturi, Fabrizio Goria, Ingunn Skre, Michele Tansella, Assen Jablensky

Aims: The Diagnostic Interview for Psychoses (DIP) is a comprehensive interview schedule for psychotic disorders, linked to the OPCRIT diagnostic algorithm, bridging the gap between fully structured, lay-administered schedules and semistructured, psychiatrist-administered interviews. Here we describe the validity, reliability and applications of the Italian version of the DIP.

Methods: The interview was translated into Italian and its content validity tested by back translation. Sixty patients, drawn from among those who contacted the South-Verona Community Mental Health Service, were included in the study. Each patient was first assessed independently by two raters, one of whom conducted the interview, while the other assumed the role of observer. Subsequently (median: 89 days), 44 of these patients were re-interviewed by a third rater, who made an independent assessment. Diagnostic validity was assessed in 18 cases, interviewed with the DIP and using the SCAN as 'gold standard'.

Results: The mean duration of the interview was 37 minutes for the inter-rater interviews and 39 minutes for the retest interviews. Good to excellent inter-rater reliability was demonstrated for both ICD-10 and DSM-IV diagnoses, while in the test-retest reliability pairwise agreement was high for half of the items. Diagnostic validity was good, with twelve out of the 18 DIP-OPCRIT diagnoses (67%) matching the SCAN diagnosis.

Conclusions: Overall, the results support the reliability and validity of the Italian translation of the DIP. The Italian version will be useful both in routine practice to establish standard reference diagnoses of psychosis and in the research field, where it can be used by academic researchers in clinical trials and epidemiological studies.

目的:精神病诊断访谈(DIP)是一份针对精神障碍的综合访谈时间表,与OPCRIT诊断算法相关联,弥合了完全结构化、非专业人员管理的时间表与半结构化、精神科医生管理的访谈之间的差距。本文介绍了意大利版DIP的有效性、可靠性及其应用。方法:将访谈内容翻译成意大利语,采用反译法对访谈内容进行效度检验。从与南维罗纳社区精神卫生服务机构联系的人中选出60名患者参与了这项研究。每位患者首先由两名评分员独立评估,其中一人进行访谈,而另一人担任观察员的角色。随后(中位数:89天),其中44名患者再次接受第三方的访谈,并进行独立评估。在18个病例中评估诊断有效性,与DIP面谈并使用SCAN作为“金标准”。结果:复试问卷的平均访谈时间为39分钟,复试问卷的平均访谈时间为37分钟。在ICD-10和DSM-IV的诊断中,显示了良好到优异的量表间信度,而在测试-重测中,一半的项目的双信度一致性很高。诊断效度良好,18个DIP-OPCRIT诊断中有12个(67%)与SCAN诊断相匹配。结论:总体而言,结果支持DIP意大利语翻译的信度和效度。意大利语版将有助于在日常实践中建立精神病的标准参考诊断,并在研究领域,它可以被学术研究人员用于临床试验和流行病学研究。
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引用次数: 0
The methodological and conceptual aspects of mortality studies in psychiatry. 精神病学死亡率研究的方法和概念方面。
Pub Date : 2010-01-01
Annibale Biggeri, Dolores Catelan

An extensive literature documented a mortality differential for natural causes between psychiatric patients and the general population. Less clear is the pattern for cancer diseases. Methodological problems arise when trying to explain such mortality gap: selection bias and reverse causation; time-dependent confounders that are also intermediate variables; complex relationships within a life course have to be considered. We try to explain such problems in terms of causal graphs. Excess risk for causes of death which are not attributable to higher prevalence of risk factors or treatment side-effects and higher mortality rates for avoidable causes have been also documented. These findings underline the need for research on health promotion and preventive programs targeted to psychiatric patients.

大量文献记录了精神病患者和普通人群之间自然原因的死亡率差异。癌症疾病的模式就不太清楚了。当试图解释这种死亡率差距时,方法学问题就出现了:选择偏差和反向因果关系;时间相关的混杂因素也是中间变量;必须考虑生命历程中的复杂关系。我们试图用因果图来解释这类问题。此外,还记录了不能归因于较高的风险因素流行率或治疗副作用的死亡原因的过度风险,以及可避免原因造成的较高死亡率。这些发现强调有必要研究针对精神病患者的健康促进和预防方案。
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引用次数: 0
Longitudinal imaging studies in schizophrenia: the relationship between brain morphology and outcome measures. 精神分裂症的纵向成像研究:脑形态与结果测量之间的关系。
Pub Date : 2010-01-01 DOI: 10.1705/524.6263
M. Bellani, N. Dusi, P. Brambilla
Imaging studies have tried to identify morphological outcome measures of schizophrenia in the last two decades. In particular, longitudinal studies have reported a correlation between larger ventricles, decreased prefrontal volumes and worse outcome. This would potentially allow to isolate subtypes of schizophrenia patients with a worse prognosis and more evident biological impairments, ultimately helping in designing specific rehabilitation interventions.
在过去的二十年里,影像学研究试图确定精神分裂症的形态学结果。特别是,纵向研究报告了脑室较大、前额叶体积减小和预后较差之间的相关性。这将有可能分离出预后较差和更明显的生物学损伤的精神分裂症患者亚型,最终有助于设计特定的康复干预措施。
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引用次数: 14
Messages to use in population-level campaigns to reduce mental health-related stigma: consensus development study. 在人口层面运动中使用的信息,以减少与精神健康有关的耻辱:共识发展研究。
Pub Date : 2010-01-01 DOI: 10.1017/s1121189x00001627
Sarah Clement, Manuela Jarrett, Claire Henderson, Graham Thornicroft

Aim: To develop and measure consensus about which type of message should be included in population-level campaigns to reduce mental health-related stigma.

Methods: A panel of 32 experts attending an international conference on mental health stigma participated in a consensus development exercise. A modified nominal group technique was used incorporating two voting rounds, an overview of research evidence and group discussion.

Results: There was high consensus (> or = 80%) regarding the inclusion of two of the message types presented--(i) recovery-oriented and (ii) see the person messages, and reasonable consensus (> or = 70%) regarding (iii) social inclusion/human rights and (iv) high prevalence of mental disorders messages. Ratings differed according to whether the participant was a psychiatrist or had personal experience of mental ill health. Analysis of the qualitative data revealed four themes: (i) benefits of messages countering the 'otherness' of people with mental ill health; (ii) problematic nature of messages referring to aetiology; (iii) message impact being dependent on the particular audience; (iv) need for specific packages of messages.

Conclusions: This study supports the use of recovery-oriented messages and see the person messages. Social inclusion/human rights messages and high prevalence of mental disorders messages also merit consideration.

目的:就应将哪种类型的信息纳入人口层面的运动中,以减少与精神健康有关的耻辱,形成并衡量共识。方法:参加心理健康污名国际会议的32名专家小组参与了共识发展练习。采用了一种改良的名义小组技术,包括两轮投票、研究证据概述和小组讨论。结果:对于所呈现的两种信息类型(i)以康复为导向和(ii)见人信息,存在高度共识(>或= 80%);对于(iii)社会包容/人权和(iv)精神障碍信息的高患病率,存在合理共识(>或= 70%)。根据参与者是精神科医生还是有精神疾病的个人经历,评分有所不同。对定性数据的分析揭示了四个主题:(i)消除精神疾病患者的"他者性"的信息的好处;(ii)有关病原学的信息存在问题;(iii)信息的影响取决于特定受众;(iv)需要特定的电文包。结论:本研究支持康复导向短信和视人短信的使用。社会包容/人权信息和精神疾病高发的信息也值得考虑。
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引用次数: 119
What can we do to reduce the burden of avoidable deaths in those with serious mental illness? 我们可以做些什么来减轻严重精神疾病患者可避免死亡的负担?
Pub Date : 2010-01-01
David Crompton, Aaron Groves, John McGrath

Individuals with schizophrenia have higher mortality rates compared to the general community. Apart from an increased risk of suicide, people with schizophrenia have an increased risk of death related to a wide range of comorbid physical conditions. There is evidence to suggest that much of this mortality is avoidable. The provision of assertive management of comorbid physical disorders has the potential to help close the differential mortality gap. While the primary data are robust, there is less empirical evidence to guide policy makers and service providers when dealing with these problems. Focused clinical programs aimed at reducing risk factors (e.g. smoking, obesity) and shared care between mental health teams and primary care providers can help reduce the burden of avoidable deaths. In light of recent evidence suggesting that the mortality gap has widened in recent decades, there is an urgent need to address the burden of avoidable deaths in those with serious mental illnesses.

与一般人群相比,精神分裂症患者的死亡率更高。除了自杀风险增加外,精神分裂症患者的死亡风险也会增加,这与多种共病的身体状况有关。有证据表明,这些死亡大多是可以避免的。提供对共病身体疾病的果断管理有可能帮助缩小死亡率差距。虽然原始数据是可靠的,但在处理这些问题时,指导政策制定者和服务提供者的经验证据较少。旨在减少风险因素(如吸烟、肥胖)和精神卫生团队与初级保健提供者之间共享护理的重点临床规划,有助于减轻可避免死亡的负担。鉴于最近有证据表明,近几十年来死亡率差距有所扩大,迫切需要解决严重精神疾病患者本可避免的死亡负担。
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引用次数: 0
Suicides in psychiatric in-patients: what are we doing wrong? 精神科住院病人的自杀:我们做错了什么?
Pub Date : 2010-01-01
Diego de Leo, Jerneja Sveticic

Given the uncontested role of psychiatric illnesses in both fatal and non-fatal suicidal behaviours, efforts are continuously made in improving mental health care provision. In cases of severe mental disorder, when intensified treatment protocols and continuous supervision are required due to individual's impaired emotional, cognitive and social functioning (including danger to self and others), psychiatric hospitalisation is warranted. However, to date there is no convincing evidence that in-patient care prevents suicide. In fact, quite paradoxically, both admissions to a psychiatric ward and recent discharge from it have been found to increase risk for suicidal behaviours. What elements in the chain of well-intentioned approaches to treating psychiatric illness and suicidality fail to protect this vulnerable population is still unclear. The same holds true for the identifications of factors that may increase the risk for suicide. This editorial discusses current knowledge on this subject, proposing strategies that might improve prevention.

鉴于精神疾病在致命和非致命自杀行为中无可争议的作用,人们不断努力改善精神卫生保健服务。在严重精神障碍的情况下,由于个人的情感、认知和社会功能受损(包括对自己和他人的危险),需要加强治疗方案和持续监督,需要精神病住院治疗。然而,到目前为止,没有令人信服的证据表明住院治疗可以预防自杀。事实上,相当矛盾的是,精神病病房的入院和最近出院都被发现增加了自杀行为的风险。在治疗精神疾病和自杀的一系列善意方法中,哪些因素未能保护这一弱势群体,目前尚不清楚。这同样适用于识别可能增加自杀风险的因素。这篇社论讨论了关于这一主题的现有知识,提出了可能改善预防的战略。
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引用次数: 0
期刊
Epidemiologia e psichiatria sociale
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