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Contrast shunting through a patent foramen ovale in a patient with pulmonary stenosis. 肺狭窄患者经卵圆孔未闭造影剂分流术。
Pub Date : 1981-01-01
P Lunde, A M Abrahamsen
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引用次数: 0
D.C. conversion in patients on amiodarone. 胺碘酮患者的dc转换。
Pub Date : 1981-01-01
M P Varma, J S Geddes, J F Pantridge

3 patients with atrial fibrillation, of varying origin, have been successfully converted to sinus rhythm by D.C. shock while on the antiarrhythmic drug amiodarone. D.C. shock did not cause rhythm disturbance. D.C. conversion may not be contraindicated in patients taking amiodarone.

3例不同来源的心房颤动患者在服用抗心律失常药物胺碘酮时,经直流电击成功转化为窦性心律。直流电休克没有造成心律紊乱。在服用胺碘酮的患者中,dc转换可能不是禁忌。
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引用次数: 0
Echocardiographic identification and analysis of function of the St. Jude medical heart valve prosthesis. 圣犹达医用心脏瓣膜假体的超声心动图鉴定及功能分析。
Pub Date : 1981-01-01
H C Hidajat, M G Gottwik, J Thormann, M Schlepper

The St. Jude medical (SJM) heart valve prosthesis presents a new bi-leaflet design which in preclinical evaluation exhibited favourable haemodynamic characteristics. Therefore clinical trials started in February 1978. The entire valve is made of pyrolytic carbon which has a poor X-ray visibility and therefore an alternative for the noninvasive routine control of valvular function and postoperative follow-up had to be found. Experimental studies in a left heart simulator provided adequate echovisualisation of both leaflets, however, depending on the direction of their motion in relation to the echobeam. Identification of both leaflets and an analysis of their motion was possible with a transducer at right angles to the leaflet axis. The experimental data were confirmed by clinical observations after implantation of the SJM prosthesis in patients. Based on the information obtained, we are providing recommendations for the implantation of the SJM prosthesis in order to achieve optimal echocardiographic visualisation of the valve and its moving parts in the postoperative follow-up.

圣犹达医疗(SJM)心脏瓣膜假体提出了一种新的双叶设计,在临床前评估中表现出良好的血流动力学特性。因此,临床试验于1978年2月开始。整个瓣膜是由热解碳制成的,x射线能见度很差,因此必须找到一种非侵入性常规控制瓣膜功能和术后随访的替代方法。然而,在左心模拟器中的实验研究提供了足够的两个小叶的回声可视化,这取决于它们相对于回波束的运动方向。在与小叶轴成直角的换能器上,可以识别两个小叶并分析它们的运动。实验数据通过患者植入SJM假体后的临床观察得到证实。根据所获得的信息,我们建议植入SJM假体,以便在术后随访中获得最佳的瓣膜及其运动部件的超声心动图显示。
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引用次数: 0
Changes in 86-rubidium uptake in erythrocytes of digoxin-treated patients, in heart failure with sinus rhythm. Relationship to clinical effects. 心力衰竭伴窦性心律患者地高辛治疗后红细胞86-铷摄取的变化。与临床效果的关系。
Pub Date : 1981-01-01
F Zannad, R J Royer, J Robert

Previous studies have shown a significant relationship between the clinical effect of digoxin and a tissue response, namely the inhibition of 86Rb uptake by the patients' erythrocytes. In the present study, this relationship is confirmed in patients, in heart failure with sinus rhythm. The slowing of the heart rate but not the QS2 index changes correlates significantly with the 86Rb uptake inhibition.

既往研究表明地高辛的临床效果与组织反应(即患者红细胞对86Rb摄取的抑制)之间存在显著关系。在本研究中,这种关系在伴有窦性心律的心力衰竭患者中得到证实。心率减慢而非QS2指数改变与86Rb摄取抑制显著相关。
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引用次数: 0
Free ball thrombus of the left atrium. 左心房游离球型血栓。
Pub Date : 1981-01-01
P E Sögaard

A case with a ball thrombus in the left atrium with a normal mitral orifice is presented. This is an extremely rare combination. The patient, aged 76, suffered from attacks of cyanosis, dyspnoea and shock because of lodging of the thrombus in the mitral orifice. In addition she had abdominal pain. The autopsy showed the thrombus in a dilated left atrium, and there were recent infarctions in the liver and a thrombus in the left renal artery. The clinical diagnosis is difficult because of the rarity of this phenomenon, but one should think of emboli from the left atrium, when an atrial fibrillation is diagnosed. One should also consider the possibility of a myxoma with these symptoms.

一例球血栓在左心房与正常二尖瓣口提出。这是一个极其罕见的组合。患者76岁,因二尖瓣口血栓淤塞,出现发绀、呼吸困难和休克等症状。此外,她还有腹痛。尸检显示血栓位于扩张的左心房,肝脏近期有梗死,左肾动脉有血栓。由于这种现象的罕见,临床诊断很困难,但当诊断为心房颤动时,应考虑左心房栓塞。伴有这些症状的患者也应考虑黏液瘤的可能性。
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引用次数: 0
Clinicopathologic assessment of arrhythmias in a case of scleroderma heart disease with sudden death. 硬皮病心脏病并发猝死1例心律失常的临床病理分析。
Pub Date : 1981-01-01
P G Marinato, G Thiene, L Menghetti, G F Buja, A Nava, A Cecchetto, L Rossi

Electrophysiologic and histopathologic correlation has been carried out in a patient with scleroderma heart disease, affected by syncopal seizures, who died of recorded ventricular fibrillation. The electrophysiological investigation disclosed dysfunction of sinoatrial conduction, revealed by sinoatrial blocks and by an abnormal return cycle pattern after premature atrial beats. Atrial effective and functional refractory periods were increased and an unusual 'pseudo-Wenckebach' phenomenon between artificial stimulus and atrium was observed during atrial pacing. Intra-AV nodal conduction time was at normal upper limits and Wenckebach-type AV block was obtained on pacing the atrium at 100 beats/min. HV conduction was moderately prolonged in the presence of left anterior hemiblock. The histopathologic substrates of these electrophysiologic disturbances were fibrosis of the sinus node, disrupted internodal pathways and atrio-AV nodal connections, and left bundle branch atrophy. As far as fatal tachyarrhythmia is concerned, myofibrillar degeneration may have contributed to its pathogenesis. It is suggested that both lesions of the ordinary myocardium and specialized conduction system account for the electrical instability of sclerodermic patients.

电生理和组织病理学的相关性已经进行了硬皮病心脏病患者,影响晕厥发作,谁死于记录心室颤动。电生理检查揭示了窦房传导功能障碍,表现为窦房传导阻滞和心房早搏后异常的返回周期模式。心房起搏时心房有效不应期和功能不应期增加,人工刺激与心房之间出现不寻常的“伪温克巴赫”现象。心房起搏100次/分时房室结传导时间正常上限,出现wenkebach型房室传导阻滞。左前半部分存在时,HV传导中度延长。这些电生理障碍的组织病理学基础是窦房结纤维化,结间通路和房室-房房结连接中断,左束支萎缩。就致死性心动过速而言,肌原纤维变性可能与其发病机制有关。提示普通心肌和特化传导系统的病变是硬皮病患者电不稳定的原因。
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引用次数: 0
The exponential rate of fiber shortening. A new angiographic measure of left ventricular contractility in man. 纤维缩短的指数速率。一种新的血管造影测量人左室收缩力的方法。
Pub Date : 1981-01-01
J Suarez de Lezo, J L Carrasco, J Pasalodos, M Sancho, J M Arizon
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引用次数: 0
Left ventricular aneurysm: pre- and postoperative haemodynamic studies at rest and during exercise. 左心室动脉瘤:休息和运动时的术前和术后血流动力学研究。
Pub Date : 1981-01-01
P A Majid, R Wardeh, P J De Feyter, J P Roos

We studied 9 men with antero-apical left ventricular aneurysms. All suffered from incapacitating angina pectoris without heart failure. Aneurysmectomy was done in 4 patients as the sole procedure while it was combined with revascularisation of the residual myocardium in the other 5. Haemodynamic measurements were made at rest and during submaximal supine-leg exercise before and approximately 6 mth after operation in each patient. Compared to the preoperative levels, we observed a significant increase in respiratory rate at rest (P less than 0.001) and during exercise (P less than 0.01), in ventilation during exercise (P less than 0.05), in mean pulmonary arterial pressure at rest (P less than 0.001) and during exercise (P less than 0.01) and in mean pulmonary wedge pressure during exercise (P less than 0.01). These changes were accompanied by a significant reduction in cardiac output during exercise (P less than 0.01) and in stroke volume at rest (P less than 0.05) and during exercise (P less than 0.01). Heart rate and blood pressure remained essentially unchanged. . The curve representing the relationship between the left ventricular stroke work and the filling pressure shifted downwards and to the right after operation compared to that before operation. Patients who show only minimal haemodynamic disturbances associated with an aneurysm, maintain an effective forward stroke volume by an augmented fibre-shortening of the residual myocardium as well as an increase in the diastolic volume of the heart. Results of our study demonstrated that the compensatory ventricular dilatation may be critical in this group of patients. Despite an increase in average ejection fraction after operation, the removal of the aneurysm led to considerable haemodynamic deterioration in all the patients studied.

我们研究了9例左心室前根尖动脉瘤患者。所有患者均患有失能性心绞痛,但无心力衰竭。4例患者单独行动脉瘤切除术,5例合并残余心肌血运重建。在每位患者手术前和手术后约6个月的休息和次最大仰卧-腿部运动期间进行血流动力学测量。与术前相比,我们观察到休息时呼吸频率(P < 0.001)和运动时呼吸频率(P < 0.01),运动时通气(P < 0.05),休息时平均肺动脉压(P < 0.001)和运动时平均肺动脉压(P < 0.01)和运动时平均肺楔压(P < 0.01)显著增加。这些变化伴随着运动时心输出量的显著减少(P < 0.01),静息时和运动时的每搏量(P < 0.05)的显著减少(P < 0.01)。心率和血压基本保持不变。与术前相比,术后左心搏功与充盈压力关系曲线下移、右移。仅表现出与动脉瘤相关的最小血流动力学障碍的患者,通过增强残余心肌的纤维缩短和心脏舒张容积的增加来维持有效的前搏容积。我们的研究结果表明,代偿性心室扩张可能是这组患者的关键。尽管术后平均射血分数增加,但动脉瘤的切除导致所有患者血流动力学明显恶化。
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引用次数: 0
Effects of intrinsic sympathetic activity of beta-blockers on SA and AV nodes in man. 受体阻滞剂内在交感神经活性对人SA和AV淋巴结的影响。
Pub Date : 1981-01-01
J F Leclercq, M D Rosengarten, S Kural, P Attuel, P Coumel

The authors compare the effects of beta-blockers without intrinsic sympathetic activity (ISA) (propranolol, 160 mg/day), moderate ISA (acebutolol, 800 mg/day) and high ISA (pindolol, 20 mg/day). The sinus rate decreases more with propranolol than with acebutolol, during the day (P less than 0.01) and during the night (P less than 0.001), whereas pindolol does not change the daylight rate and increases the nighttime rate (P less than 0.001). The ventricular rate during atrial fibrillation (AV nodal transmission) is modified as is sinus rate. There is no significant difference between propranolol and acebutolol, and a highly significant difference between pindolol and propranolol (P less than 0.001) or acebutolol (P less than 0.01). Moreover, the eurythmic effect of beta-blockers, making RR intervals more regular, is maximal with propranolol and minimal with pindolol, as judged on RR interval histograms. The ISA of the beta-blockers is of major importance for the clinical use of these drugs, and in the case of SA or AV node dysfunction ISA can be useful, but it can obscure the beneficial effects of beta-blocking therapy.

作者比较了无内源性交感神经活动(ISA)的β受体阻滞剂(心得安,160毫克/天)、中等ISA(乙酰丁胺醇,800毫克/天)和高ISA(品多洛尔,20毫克/天)的效果。在白天(P < 0.01)和夜间(P < 0.001),心得安组窦率下降幅度大于乙酰丁胺醇组,而品多洛尔组窦率升高(P < 0.001),但对白天窦率无明显影响。房颤(房室结传递)期间的心室率和窦率一样被改变。心得安与乙酰布洛尔无显著差异,品多洛尔与心得安(P < 0.001)、乙酰布洛尔(P < 0.01)差异极显著。此外,从RR间期直方图判断,受体阻滞剂的心律调节作用,使RR间期更有规律,在心得安组最大,在品多洛尔组最小。受体阻滞剂的ISA对这些药物的临床应用具有重要意义,在SA或房室结功能障碍的情况下,ISA可能是有用的,但它可能会掩盖β阻断治疗的有益效果。
{"title":"Effects of intrinsic sympathetic activity of beta-blockers on SA and AV nodes in man.","authors":"J F Leclercq,&nbsp;M D Rosengarten,&nbsp;S Kural,&nbsp;P Attuel,&nbsp;P Coumel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors compare the effects of beta-blockers without intrinsic sympathetic activity (ISA) (propranolol, 160 mg/day), moderate ISA (acebutolol, 800 mg/day) and high ISA (pindolol, 20 mg/day). The sinus rate decreases more with propranolol than with acebutolol, during the day (P less than 0.01) and during the night (P less than 0.001), whereas pindolol does not change the daylight rate and increases the nighttime rate (P less than 0.001). The ventricular rate during atrial fibrillation (AV nodal transmission) is modified as is sinus rate. There is no significant difference between propranolol and acebutolol, and a highly significant difference between pindolol and propranolol (P less than 0.001) or acebutolol (P less than 0.01). Moreover, the eurythmic effect of beta-blockers, making RR intervals more regular, is maximal with propranolol and minimal with pindolol, as judged on RR interval histograms. The ISA of the beta-blockers is of major importance for the clinical use of these drugs, and in the case of SA or AV node dysfunction ISA can be useful, but it can obscure the beneficial effects of beta-blocking therapy.</p>","PeriodicalId":72971,"journal":{"name":"European journal of cardiology","volume":"12 6","pages":"367-75"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17180229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Character of mitral valve flow in left atrial tumor. 左心房肿瘤二尖瓣血流特征。
Pub Date : 1981-01-01
P Niederle, Z Stĕpánek, A Grospic, J Ressl, P Firt, I Beránek, M Dubovska

The pulsed Doppler echocardiography (PDE) was used to evaluate the character of mitral valve flow in a large atrial tumor. The tumor obstructed the mitral orifice during diastole. PDE findings, however, showed normal triphasic diastolic flow within the actual mitral orifice and no changes typical for mitral stenosis. The same turbulence pattern as in mitral stenosis was detected in the left ventricle. In addition, PDE revealed the presence of mild mitral regurgitation in agreement with angiography.

应用脉冲多普勒超声心动图(PDE)评价大心房肿瘤二尖瓣血流特征。肿瘤在舒张期阻塞二尖瓣口。然而,PDE结果显示,在实际的二尖瓣口内正常的三相舒张期血流,没有二尖瓣狭窄的典型变化。在左心室检测到与二尖瓣狭窄相同的湍流模式。此外,PDE显示轻度二尖瓣反流与血管造影一致。
{"title":"Character of mitral valve flow in left atrial tumor.","authors":"P Niederle,&nbsp;Z Stĕpánek,&nbsp;A Grospic,&nbsp;J Ressl,&nbsp;P Firt,&nbsp;I Beránek,&nbsp;M Dubovska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The pulsed Doppler echocardiography (PDE) was used to evaluate the character of mitral valve flow in a large atrial tumor. The tumor obstructed the mitral orifice during diastole. PDE findings, however, showed normal triphasic diastolic flow within the actual mitral orifice and no changes typical for mitral stenosis. The same turbulence pattern as in mitral stenosis was detected in the left ventricle. In addition, PDE revealed the presence of mild mitral regurgitation in agreement with angiography.</p>","PeriodicalId":72971,"journal":{"name":"European journal of cardiology","volume":"12 6","pages":"357-65"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18252072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
European journal of cardiology
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