Background: Acute pancreatitis (AP) is an acute inflammatory condition of the pancreas which may extend to local and distant extra pancreatic tissues. It is a life-threatening disease that has many causes, few effective treatments and numerous serious complications. Early diagnosis of acute pancreatitis and effective treatment can significantly reduce the mortality and morbidity of such cases.
{"title":"Prediction of Severity of Acute Pancreatitis by Biochemical Markers: A Tertiary Care Hospital Study","authors":"Shanjidah Hoque, Rifat Hassan, Naheen Rezuan Shehran Asif","doi":"10.26502/fjhs.132","DOIUrl":"https://doi.org/10.26502/fjhs.132","url":null,"abstract":"Background: Acute pancreatitis (AP) is an acute inflammatory condition of the pancreas which may extend to local and distant extra pancreatic tissues. It is a life-threatening disease that has many causes, few effective treatments and numerous serious complications. Early diagnosis of acute pancreatitis and effective treatment can significantly reduce the mortality and morbidity of such cases.","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135651088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hénoch Kabala Tshasuma, Chamy Lubamba Cham, Joseph Bulanda Nsambi, Charles Wembonyama Mpoy
Objective: To determine the prevalence and identify risk factors for gestational diabetes mellitus (GDM) in Likasi City in the Democratic Republic of the Congo.
目的:了解刚果民主共和国利卡西市妊娠期糖尿病(GDM)患病率及危险因素。
{"title":"Prevalence and Risk Factors of Gestational Diabetes Mellitus in Likasi, in The Democratic Republic of The Congo: A Preliminary Study","authors":"Hénoch Kabala Tshasuma, Chamy Lubamba Cham, Joseph Bulanda Nsambi, Charles Wembonyama Mpoy","doi":"10.26502/fjhs.137","DOIUrl":"https://doi.org/10.26502/fjhs.137","url":null,"abstract":"Objective: To determine the prevalence and identify risk factors for gestational diabetes mellitus (GDM) in Likasi City in the Democratic Republic of the Congo.","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"386 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136209868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Validation of CTP, MELD & MELD Na Scoring Systems for Predicting Treatment Outcome of Cirrhotic patients in Bangladesh- An observational study","authors":"Syeda Nur-E-Jannat, Dewan Saifuddin Ahmed","doi":"10.26502/fjhs.115","DOIUrl":"https://doi.org/10.26502/fjhs.115","url":null,"abstract":"","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69347461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Klotho is a well-known tumor suppressor hormone that exhibits anti-cancer and anti-aging properties. Klotho levels are low or non-existent in cancer patients. Klotho protein levels decrease with aging; maintaining consistent levels may prevent disease and promote healthier aging. Metadichol is a nanoemulsion of long-chain alcohols C26, C28, and C30, of which C-28 constitutes over 85%. Any small molecule that can elevate Klotho can, in principle, help reverse many diseases in which Klotho levels are low. Previously, we showed that treatment of the pancreatic cancer cell lines PANC1, MIA-PACA, and COLO-205, combined with Metadichol, a lipid emulsion consisting of long-chain alcohols at 1-100 pg/mL concentrations, resulted in a 4- to 10-fold increase in Klotho expression as determined by qRT-PCR, This study aimed to demonstrate that Metadichol promotes Klotho expression in a wide variety of cell lines, such as primary cancer, stem, and somatic cell lines. Cells were treated with various concentrations of Metadichol ranging from 1 pg (picogram) to 1µg 9microgram). Three-to-fifteen-fold increase in Klotho expression was observed compared with baseline, as measured by qRT-PCR and qualified by western blot analysis. Metadichol is a natural agonist of Klotho expression and is non-toxic at levels up to 5000 mg/kg in rats. and has a potential therapeutic role in cancer and reversing aging.
{"title":"Metadichol; An Agonist that Expresses the Anti-aging gene Klotho in Various Cell Lines","authors":"Palayakotai R. Raghavan","doi":"10.26502/fjhs.135","DOIUrl":"https://doi.org/10.26502/fjhs.135","url":null,"abstract":"Klotho is a well-known tumor suppressor hormone that exhibits anti-cancer and anti-aging properties. Klotho levels are low or non-existent in cancer patients. Klotho protein levels decrease with aging; maintaining consistent levels may prevent disease and promote healthier aging. Metadichol is a nanoemulsion of long-chain alcohols C26, C28, and C30, of which C-28 constitutes over 85%. Any small molecule that can elevate Klotho can, in principle, help reverse many diseases in which Klotho levels are low. Previously, we showed that treatment of the pancreatic cancer cell lines PANC1, MIA-PACA, and COLO-205, combined with Metadichol, a lipid emulsion consisting of long-chain alcohols at 1-100 pg/mL concentrations, resulted in a 4- to 10-fold increase in Klotho expression as determined by qRT-PCR, This study aimed to demonstrate that Metadichol promotes Klotho expression in a wide variety of cell lines, such as primary cancer, stem, and somatic cell lines. Cells were treated with various concentrations of Metadichol ranging from 1 pg (picogram) to 1µg 9microgram). Three-to-fifteen-fold increase in Klotho expression was observed compared with baseline, as measured by qRT-PCR and qualified by western blot analysis. Metadichol is a natural agonist of Klotho expression and is non-toxic at levels up to 5000 mg/kg in rats. and has a potential therapeutic role in cancer and reversing aging.","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135953450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Phani Kumar, Mashingbonio Dirinamai, B. Manishkumar, Susheel kumar saini, Ajay kumar saini, S. Kumari
{"title":"Methylmalonic acidemia caused by Homozygous Missense variant c.1837C>T in Exon 11 of the MMUT gene which is Variant of Uncertain Significance: A Case Report","authors":"G. Phani Kumar, Mashingbonio Dirinamai, B. Manishkumar, Susheel kumar saini, Ajay kumar saini, S. Kumari","doi":"10.26502/fjhs.106","DOIUrl":"https://doi.org/10.26502/fjhs.106","url":null,"abstract":"","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69347398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of Methicillin-Resistant Staphylococcus Aureus with Their Susceptibility Pattern and Their Association of Panton-Valentine Leukocidin Gene in a Tertiary Care Hospital in Bangladesh","authors":"R. Khatun, Sk. Shehab Hasan, S. Akter, N. Khatun","doi":"10.26502/fjhs.111","DOIUrl":"https://doi.org/10.26502/fjhs.111","url":null,"abstract":"","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69347441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dadé Ben Sidi Haidara, B. K, C. A, Traoré Ak, Traore Sa, T. L, Coulibaly Mb, K. M, Diallo Ab, T. B, T. T, Poma H, T. M
{"title":"Evolution of The Main Hospital Activity Indicators in Sikasso Hospital, Mali, 2015-2021","authors":"Dadé Ben Sidi Haidara, B. K, C. A, Traoré Ak, Traore Sa, T. L, Coulibaly Mb, K. M, Diallo Ab, T. B, T. T, Poma H, T. M","doi":"10.26502/fjhs.118","DOIUrl":"https://doi.org/10.26502/fjhs.118","url":null,"abstract":"","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69347508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Somatic Cell-Fusion and/or Co-Culturing: A Mechanism for Cell Re-Programming Prior to Cell Therapy of Neurodegenerative Diseases","authors":"A. Chakraborty, Anil Diwan","doi":"10.26502/fjhs.094","DOIUrl":"https://doi.org/10.26502/fjhs.094","url":null,"abstract":"","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69347749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rahman Smr, Rahman As, Pramanik Ak, B. R, Rahim Ka, Yesmin Ms, Bhuiyan Mma, Islam Mt, R. M, Islam Ms, Sultana T
{"title":"Low Serum Magnesium Level is Associated with Hypertension in Bangladeshi Adults","authors":"Rahman Smr, Rahman As, Pramanik Ak, B. R, Rahim Ka, Yesmin Ms, Bhuiyan Mma, Islam Mt, R. M, Islam Ms, Sultana T","doi":"10.26502/fjhs.095","DOIUrl":"https://doi.org/10.26502/fjhs.095","url":null,"abstract":"","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69347776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Received: January 18, 2023 Accepted: January 27, 2023 Published: February 10, 2023 Abstract Pneumoperitoneum is the presence of air in the abdomen. This can be due to a wide variety of etiologies, many of which are surgical emergencies, yet it can also present as a chronic symptom of underlying pathology. Pneumoperitoneum can be due to primary (idiopathic) or secondary causes, of which the causes are numerous. This can even be due to other pathology unrelated to the GI tract, such as pathology of the thoracic cavity. We present a case of chronic pneumatosis intestinalis that was due to peritoneal blebs likely secondary to an alveolar-peritoneal fistula through the right hemidiaphragm. Chronic, Massive Pneumoperitoneum in a Patient without Signs of Peritonitis
{"title":"Chronic, Massive Pneumoperitoneum in a Patient without Signs of Peritonitis","authors":"M. Kubina, M. Mouchli","doi":"10.26502/fjhs.096","DOIUrl":"https://doi.org/10.26502/fjhs.096","url":null,"abstract":"Received: January 18, 2023 Accepted: January 27, 2023 Published: February 10, 2023 Abstract Pneumoperitoneum is the presence of air in the abdomen. This can be due to a wide variety of etiologies, many of which are surgical emergencies, yet it can also present as a chronic symptom of underlying pathology. Pneumoperitoneum can be due to primary (idiopathic) or secondary causes, of which the causes are numerous. This can even be due to other pathology unrelated to the GI tract, such as pathology of the thoracic cavity. We present a case of chronic pneumatosis intestinalis that was due to peritoneal blebs likely secondary to an alveolar-peritoneal fistula through the right hemidiaphragm. Chronic, Massive Pneumoperitoneum in a Patient without Signs of Peritonitis","PeriodicalId":73052,"journal":{"name":"Fortune journal of health sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69347779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}