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Clinical and Laboratory-based Diagnosis in Cases Suspected with COVID-19; An Updated and Comprehensive Systematic Review Study 疑似COVID-19病例的临床和实验室诊断一项最新的全面系统综述研究
Pub Date : 2022-01-01 DOI: 10.26502/fjhs.050
Nazila Bahmaie, M. Ajorloo, Maryam Mohammadbeigi, Parisa Abedi Elkhichi, Sheida Alizadeh, S. Soroush, F. Rajabi, E. Nouri, Pourandokht Farhangian, N. Mohammadi, A. Mohammadyari, Maryam Mohammadi, Mohammad Javad Hajkazemi, M. Shamohammadi, Mahnoush Bahrampour, Samin Rahimi, Mahsa Jalilinezhad, Sahar Serajian, Zahra Dorosti, Samira Lorestani, Seyed Mohammad Mohyeddin Kazemeini, Sina Ekhlasi, Sheida Janati, N. Rezaei
Journal of Health Sciences 5 (2022): 126-158. Abstract Objectives A novel coronavirus disease 2019 (COVID-19) was identified in Wuhan , China , which quickly involved majority of the countries all around the world. Due to the high rate of mortality and morbidity, needless to say the importance of accurate and early diagnosis, especially in suspected and asymptomatic cases. Hence, in this article, authors tried to provide practical and standardized diagnostic approaches for cases suspected with COVID-19 infection. Data of this review study were collected from 7 search engine/databases, commencing from December 2019 to June 2021 by using 6 keywords according to Medical Subject Headings (MeSH) terms and our inclusion/exclusion criteria. Result Due to various clinical manifestations of COVID-19, and high potential for mutagenicity, identification of suspected patients is of great importance for effective control of infection, and improvement of clinical decisions. Therefore, medical history of the patients, clinical signs and symptoms, chest computational tomography, serological and molecular diagnosis can be effective in faster identification of mentioned patients. In spite of the fact that molecular tests have been considered as the gold standard for diagnosis of COVID-19, but there is still high rate of false-negativity. Then, combinative usage of the complementary tests can reduce any misinterpretations for suspected cases. Screening for suspected cases in the shortest possible turnaround time is dependent on the appropriate diagnostic approaches. Subsequently, this allows physicians immediately provide proper medical interventions for suspected patients who are at greater risk for developing more serious complications than COVID-19 like severe nosocomial infections.
卫生科学杂志5(2022):126-158。摘要目的新型冠状病毒病2019 (COVID-19)在中国武汉被发现,并迅速波及全球大多数国家。由于死亡率和发病率高,准确和早期诊断的重要性不言而喻,特别是在疑似和无症状病例中。因此,在本文中,作者试图为疑似COVID-19感染病例提供实用和标准化的诊断方法。本综述性研究的数据从2019年12月至2021年6月从7个搜索引擎/数据库中收集,根据医学主题词(MeSH)术语和我们的纳入/排除标准使用6个关键词。结果新型冠状病毒肺炎临床表现多样,具有较高的致突变性,识别疑似患者对有效控制感染、提高临床决策水平具有重要意义。因此,通过患者的病史、临床体征和症状、胸部计算机断层扫描、血清学和分子诊断可以有效地更快地识别上述患者。尽管分子检测被认为是新冠肺炎诊断的金标准,但假阴性率仍然很高。然后,结合使用补充测试可以减少对疑似病例的任何误解。在尽可能短的周转时间内筛查疑似病例取决于适当的诊断方法。随后,这使得医生能够立即为疑似患者提供适当的医疗干预措施,这些患者比COVID-19更有可能出现更严重的并发症,如严重的医院感染。
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引用次数: 0
Knowledge, Attitude and Practice towards Prevention of COVID-19 in Jigjiga Town, Ethiopia: A Cross-Sectional Study 埃塞俄比亚吉吉加镇预防COVID-19的知识、态度和做法:一项横断面研究
Pub Date : 2022-01-01 DOI: 10.26502/fjhs.052
Abdifatah Elmi Farah, O. Oladeji, Abdulahi Haji Abas, A. Tahir
a disease by the most recently discovered novel coronavirus. The first confirmed case in Ethiopia was recorded on 13 th of March 2020 and on 26 th of April in Somali region of Ethiopia. The objective of this study is to assess the level of knowledge, attitude, and preventive practices and their associated factors in Jigjiga town of Ethiopia. education, number rooms, Knowledge score and attitude score have shown significant association with the preventive practices assessed. Conclusion The knowledge, attitude and practice level towards COVID-19 is not optimum at household level in Jigjiga town. More community engagement targeting households is necessary to achieve an optimal behavioral change.
由最新发现的新型冠状病毒引起的疾病。埃塞俄比亚第一例确诊病例分别于2020年3月13日和4月26日在埃塞俄比亚索马里地区记录在案。本研究的目的是评估埃塞俄比亚吉吉加镇的知识水平、态度和预防措施及其相关因素。教育程度、房间数量、知识得分和态度得分与评估的预防措施有显著相关性。结论集集加镇家庭对新冠肺炎的知识、态度和行为水平均不理想。为了实现最佳的行为改变,需要更多针对家庭的社区参与。
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引用次数: 0
To Determine the Frequency of Endometrial Polyps in Patients Presenting with Irregular per Vaginal Bleeding 目的探讨不规则阴道出血患者发生子宫内膜息肉的频率
Pub Date : 2022-01-01 DOI: 10.26502/fjhs.053
A. Malik, Laila Zeb
with Irregular
与不规则
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引用次数: 1
Cervical Cancer - Its Prevalence, Risk factors, Imaging, and Treatment 子宫颈癌的流行、危险因素、影像学和治疗
Pub Date : 2022-01-01 DOI: 10.26502/fjhs.069
Mahrukh Ikram, Muhammad Arslan, Iqra Fasih
Cervix uteri is a leading type of cancer exclusive to women. It is gradually spread-ing over different regions of the world without any prominent cause or reason behind it. This disease affects the lower part of the uterus (start of the cervix area). Most reports advocate the role of Human Papilloma Virus (HPV) infection in developing this cancer. Environmental and age-related factors also play an important role, and these areas are open for research to discover exact relationships. However, in this article, we have summarized and revealed some important statistics about cervix uteri cancer that describe its epidemiology, risk factors, relation to age, treatments, staging and similar aspects.
子宫子宫颈癌是女性独有的主要癌症类型。它在没有任何明显原因的情况下逐渐蔓延到世界不同地区。这种疾病影响子宫的下部(子宫颈区域的开始)。大多数报告主张人类乳头瘤病毒(HPV)感染在发展这种癌症中的作用。环境和年龄相关的因素也起着重要作用,这些领域的研究是开放的,以发现确切的关系。然而,在本文中,我们总结和揭示了一些关于子宫颈癌的重要统计数据,描述了其流行病学,危险因素,与年龄,治疗,分期和类似方面的关系。
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引用次数: 0
Efficacy of Methotrexate versus Azathioprine and Their Steroid Sparing Role in the Treatment of Chronic Actinic Dermatitis: A Randomized Control Trial 甲氨蝶呤与硫唑嘌呤的疗效及其类固醇保留作用治疗慢性光化性皮炎:一项随机对照试验
Pub Date : 2022-01-01 DOI: 10.26502/fjhs.047
Mohammad Majid Paracha, Abdul Qayum khan, F. Sagheer, Hina Zahoor
Background Azathioprine is first line immunosuppressive agent in treatment of chronic actinic dermatitis. Steroid sparing role of methotrexate has been effective in different dermatosis and it seems reasonable to use it in the treatment of chronic actinic dermatitis. Methods Patients with chronic actinic dermatitis were randomized to receive methotrexate and systemic steroids in group A and azathioprine and systemic steroids in group B. Tapering of systemic steroids was started at 4 weeks. The response to treatment, exacerbation of disease and side effects of medications were assessed at 4, 8 and 16 weeks follow-up by calculating percentage PASI reduction. Result Among 168 patients, 35(38.09%) patients in group A and 37(44%) patients in group B showed efficacy to the treatment at 4 weeks. On follow-up at 16 weeks, exacerbation of skin lesions was observed in total of 14 (19.44%) patients on tapering of systemic steroids among 72 (42.9%) patients previously showing efficacy to the combination therapy, with 9(24.71%) patients in group A and 5(13.51%) patients in group B.
背景硫唑嘌呤是治疗慢性光化性皮炎的一线免疫抑制剂。甲氨蝶呤的类固醇保留作用在不同的皮肤病中都是有效的,在慢性光化性皮炎的治疗中似乎是合理的。方法慢性光化性皮炎患者随机分为甲氨蝶呤和全身类固醇治疗组,硫唑嘌呤和全身类固醇治疗组,4周开始逐渐减少全身类固醇治疗。通过计算PASI减少百分比,在随访4、8和16周时评估治疗反应、疾病恶化和药物副作用。结果168例患者中,A组35例(38.09%),B组37例(44%),治疗4周有效。在16周的随访中,在72例(42.9%)先前对联合治疗有效的患者中,共有14例(19.44%)患者在全体性类固醇减量治疗后皮肤病变加重,其中A组9例(24.71%),B组5例(13.51%)。
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引用次数: 0
Role of Laparoscopy in Female Infertility 腹腔镜在女性不孕症中的作用
Pub Date : 2022-01-01 DOI: 10.26502/fjhs.054
Laila Zeb, A. Malik
Background: Infertility is the failure of couple to achieve a clinical pregnancy after 12 months or more of unprotected sexual intercourse. Laparoscopy is an important diagnostic procedure to identify the causes for infertility. Aim and Objective: Emphasis on role of laparoscopy in diagnosing causes for female infertility. Material and method: This Cross-sectional study was conducted in Obstetrics and Gynecology A Unit of Medical Teaching Institute, Lady Reading Hospital, Peshawar from 1st January 2019 till 31st December 2019. Sample size was 221 calculated by using Open-Epi calculator. The patients who refused procedure or with male factor infertility or having medical disorders like hypertension, cardiac disease, un- controlled diabetes were excluded. Non-probable convenient sampling technique used and a structured questionnaire filled. P-value > 0.005 and 95% Confidence interval considered as significant. Data analyzed using SPSS version 20. For statistical analysis, frequencies, percentages and Mean ± SD were used for continuous variables. Results: Total 221 patients were selected. (71.4%) patients had primary, 63 (28.5%) secondary infertility. Mean age at presentation 27.6 years and 28.8 years in primary and secondary infertility. The mean duration of marriage was 4.51 years in primary and 5.05 years in secondary infertility. 180 (81.4%) (30%), Endometriosis 27 (12.2%) and fibroid uterus 10(4.5%). Conclusion: Laparoscopy is minimally invasive, convenient, safe and economic procedure for diagnosis of infertility in females.
背景:不孕症是夫妇在无保护性交12个月或更长时间后未能实现临床妊娠。腹腔镜检查是确定不孕原因的重要诊断方法。目的与目的:探讨腹腔镜在女性不孕症病因诊断中的作用。材料和方法:本横断面研究于2019年1月1日至2019年12月31日在白沙瓦雷丁夫人医院医学教学研究所妇产科A单元进行。采用Open-Epi计算器计算样本量221例。拒绝手术、男性因素不孕、高血压、心脏病、糖尿病等内科疾病的患者排除在外。采用非可能方便抽样技术,并填写结构化问卷。p值> 0.005和95%置信区间认为显著。数据分析使用SPSS版本20。连续变量采用频率、百分比和Mean±SD进行统计分析。结果:共纳入221例患者。原发性不孕症患者占71.4%,继发性不孕症患者占63例(28.5%)。原发性和继发性不孕症的平均发病年龄分别为27.6岁和28.8岁。原发不孕的平均婚姻时间为4.51年,继发不孕的平均婚姻时间为5.05年。子宫内膜异位症27例(12.2%),子宫肌瘤10例(4.5%)。结论:腹腔镜检查是一种微创、方便、安全、经济的女性不孕症诊断方法。
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引用次数: 1
Application of the Clinical Reasoning Process for the Rehabilitation of a Case with Cervicogenic Pain 临床推理过程在1例宫颈源性疼痛康复中的应用
Pub Date : 2022-01-01 DOI: 10.26502/fjhs.081
Md Waliul Islam, Md. Kutub Uddin, Faruq Ahmed, Md Shujayt Gani, Mohammad Nazmul Hasan, Md Jubair Hassan
Background: The method through which a therapist engages with a patient is known as clinical reasoning. During this process, the therapist gathers data, develops, and tests hypotheses, and then uses this data to determine the best course of action for diagnosis and therapy. It is described as an inferential procedure used by practitioners to gather and assess information and make decisions on the diagnosis and treatment of patient problems. Aim: The aim of this study is to describe the rehabilitation of a solo case with cervical radiculopathy by using clinical reasoning process Method: A case study of typical cervical radiculopathy managed by using clinical reasoning process and advance evidence-based physiotherapy treatment to reduce pain, increase ROM and improve functional ability. Result: After six weeks of treatment, there was a reduction in pain, an increase in range of motion, and a change in disability status as measured by the neck disability index. Conclusion: Finally, this case study states that application of the clinical reasoning process is beneficial for rehabilitation programs.
背景:治疗师与病人接触的方法被称为临床推理。在这个过程中,治疗师收集数据,发展和测试假设,然后使用这些数据来确定诊断和治疗的最佳行动方案。它被描述为从业人员用来收集和评估信息并对患者问题的诊断和治疗做出决定的推理程序。目的:本研究的目的是通过临床推理过程描述一个单独的颈椎神经根病病例的康复。方法:以典型的颈椎神经根病为例,采用临床推理过程治疗,并推进循证物理治疗,以减轻疼痛,增加ROM和改善功能能力。结果:治疗六周后,疼痛减轻,活动范围增加,颈部残疾指数测量的残疾状态改变。结论:最后,本案例研究表明临床推理过程的应用对康复计划是有益的。
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引用次数: 0
Medications and Supplements Prescription Patterns during COVID 19 Pandemic in Yemen: A Questionnaire-Based Study. 也门 COVID 19 大流行期间的药物和补充剂处方模式:基于问卷的研究。
Pub Date : 2022-01-01 Epub Date: 2022-09-05 DOI: 10.26502/fjhs.079
Abdullah Chahin, Ghulam Dhabaan, Abdulrahman Buhaish, Mahmoud Shorman

Introduction: the study aims to better understand the COVID-19 prescription treatments and over the counter regimens in Yemen in view of limited published data and limited availability of COVID-19 testing.

Methods: A 34 question web-based survey was distributed on social media outlets targeting people in Yemen. Data aggregation, analysis, and visualization were performed using Tableau and Microsoft Excel.

Results: 2341 individuals reported symptoms concerning for COVID-19 infection, with 25.4% reporting a chronic medical condition. Female patients were less likely to receive medications for treatment in all age groups examined. Azithromycin was the most prescription medication prescribed (32.8%) and vitamin C being the most supplement used (62%). Around 5.5% were on Hydroxychloroquine prophylaxis prior to their diagnosis and only 12.9% of them continued using after diagnosis.

Conclusions: This study provides some important information about the commonly observed treatments and prescription patterns during the COVID-19 pandemic in Yemen during May- July of 2020. The study reflects the influence of global trends in medication prescription even in resource-limited countries.

导言:本研究旨在更好地了解也门的 COVID-19 处方治疗和非处方治疗情况,因为已公布的数据有限,而且 COVID-19 检测的可用性也有限:方法:在社交媒体上针对也门民众发布了一项 34 个问题的网络调查。结果:2341 人报告了与 COVID-19 感染有关的症状,其中 25.4% 的人报告了慢性疾病。在调查的所有年龄组中,女性患者接受药物治疗的可能性较低。阿奇霉素是处方最多的药物(32.8%),维生素 C 是使用最多的补充剂(62%)。约5.5%的人在确诊前服用羟氯喹预防,只有12.9%的人在确诊后继续服用:这项研究提供了一些重要信息,说明了 2020 年 5 月至 7 月 COVID-19 在也门流行期间常见的治疗方法和处方模式。这项研究反映了全球药物处方趋势的影响,即使在资源有限的国家也是如此。
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引用次数: 0
Psychological Impact of COVID-19 on Community Pharmacists: A Cross-Sectional Study in Lusaka District, Zambia COVID-19对社区药剂师的心理影响:赞比亚卢萨卡地区的横断面研究
Pub Date : 2022-01-01 DOI: 10.26502/fjhs.087
Steward Mudenda, Patrick Mainza, R. Mfune, W. Mufwambi, Jimmy M. Hangoma, R. Mutati, Kampamba, T. L. Muungo, C. Hikaambo, M. Kampamba, V. Daka
Introduction The coronavirus disease 2019 (COVID-19) pandemic has caused serious health problems globally. This has included increased psychological challenges among frontline healthcare workers (HCWs). Community pharmacists are critical in the fight against COVID-19 and in sensitising the public about vaccinations and other public health interventions. However, little is known about the psychological impact of COVID-19 and the acceptance of vaccinations among community pharmacists in Zambia. Therefore, this study assessed the psychological impact of COVID-19 among community pharmacists in Lusaka, Zambia. Materials and Methods: This cross-sectional study was conducted among 188 community pharmacists from August to October 2021 using a structured questionnaire. Statistical Package for Social Sciences (SPSS) version 22.0 was used to analyse the data. The statistical significance was conducted at a 95% confidence level. Results: Of the 188 participants, 108 (57.4%) were male, while 80 (42.6%) were female. Most of the participants were in the age group of 20−30 years (n=109, 58.0%). The study found that 36.7% of the participants experienced anxiety, while 50.5% experienced depression. Anxiety was associated with fear of dying from COVID-19 if one contracted it (p=0.001), fear of infecting loved ones if infected (p=0.003) and experiencing a traumatic event (p=0.036). Depression was associated with a fear of dying if one contracted COVID-19 (p=0.001). Overall, about 70.2% of the participants expressed willingness to receive the COVID-19 vaccine. Conclusion: Community pharmacists experienced anxiety and depression due to the COVID-19 pandemic. Most of the community pharmacists were willing to receive the COVID-19 vaccine. There is a need for urgent interventions to address the mental health challenges of community pharmacists during pandemics.
2019冠状病毒病(COVID-19)大流行在全球范围内造成了严重的健康问题。这包括一线医护人员(HCWs)面临的心理挑战增加。社区药剂师在抗击COVID-19和提高公众对疫苗接种和其他公共卫生干预措施的认识方面至关重要。然而,人们对COVID-19的心理影响以及赞比亚社区药剂师对疫苗接种的接受程度知之甚少。因此,本研究评估了COVID-19对赞比亚卢萨卡社区药剂师的心理影响。材料与方法:本横断面研究于2021年8月至10月对188名社区药师进行了结构化问卷调查。使用SPSS 22.0版本对数据进行分析。统计学意义在95%的置信水平上进行。结果:188名参与者中,男性108人(57.4%),女性80人(42.6%)。大多数参与者年龄在20 ~ 30岁之间(n=109, 58.0%)。研究发现,36.7%的参与者经历过焦虑,50.5%的人经历过抑郁。焦虑与害怕感染COVID-19后死亡(p=0.001)、害怕感染亲人(p=0.003)和经历创伤性事件(p=0.036)相关。如果感染COVID-19,抑郁与死亡恐惧相关(p=0.001)。总体而言,约70.2%的参与者表示愿意接种COVID-19疫苗。结论:社区药师因新冠肺炎大流行而出现焦虑和抑郁。大部分社区药师愿意接种新冠肺炎疫苗。有必要采取紧急干预措施,以应对大流行病期间社区药剂师面临的心理健康挑战。
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引用次数: 0
Role of National Public Health Institutes for a Stronger Health System in Africa 国家公共卫生机构在加强非洲卫生系统中的作用
Pub Date : 2022-01-01 DOI: 10.26502/fjhs.090
Haftom Taame Desta, N. Mayet, Alex Riolexus Ario, R. Tajudeen
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引用次数: 1
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Fortune journal of health sciences
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