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Editorial: Dismantling disparities: advancing mental healthcare access for diverse youth. 社论:消除差距:促进不同青年获得精神卫生保健。
Pub Date : 2026-01-23 eCollection Date: 2025-01-01 DOI: 10.3389/frcha.2025.1758566
Miya L Barnett, Jason F Jent, Dainelys Garcia
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引用次数: 0
Adolescents' perceived school climate, self-reported mental health, and frequency of physical activity: associations and gender differences. 青少年感知的学校气氛、自我报告的心理健康和身体活动频率:关联和性别差异
Pub Date : 2026-01-16 eCollection Date: 2025-01-01 DOI: 10.3389/frcha.2025.1674304
Baiba Martinsone, Eva Ģērmane, Jesslynn R Neves-McCain

This study aimed to test whether a more positively perceived school climate and more frequent physical activity are related to better mental health among adolescents. Additionally, the research examined the gender differences in adolescents' self-reported mental health, perceptions of school climate, and the frequency of their physical activity. A total of 2,526 students (52.6% girls; 43.8% boys) from grades 5 through 12 from various schools in Latvia participated in the study. The research used the Georgia School Climate Survey (GSCS) and three questions from the Physical Activity Questionnaire for Older Children (PAQ-C). The results of multiple linear regression analysis confirmed that a more positively perceived overall school climate (B = -1.05, p < .001) and greater engagement in physical activity (B = -1.05, p < .001) were both significantly associated with better mental health in adolescents. The findings also revealed gender differences in self-reported mental health: girls reported significantly higher levels of mental health difficulties (M = 2.22 compared to boys' M = 1.87). In contrast, girls rated such factors of the school climate as adult and peer support, social/civic learning and physical environment more positively, while boys reported significantly higher levels of physical activity (28.98 compared to girls' 26,43). Despite such limitations of the research as self-report bias and cross-sectional design, these findings underscore the critical role of the school environment in predicting mental health outcomes, highlighting the need for targeted improvements that both mitigate risk factors and promote inclusive access to physical activity among all students.

本研究旨在测试更积极的学校氛围和更频繁的体育活动是否与青少年更好的心理健康有关。此外,该研究还调查了青少年自我报告的心理健康、对学校气氛的看法和体育活动频率方面的性别差异。拉脱维亚各学校五年级至十二年级共有2,526名学生(52.6%为女生,43.8%为男生)参加了这项研究。这项研究使用了乔治亚州学校气候调查(GSCS)和《大龄儿童体育活动问卷》(PAQ-C)中的三个问题。多元线性回归分析的结果证实,学生对整体学校氛围的感知越积极(B = -1.05, p p
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引用次数: 0
Mothers' eating disorder history and mother and infant attention to food during infant meal times: a candidate for intergenerational transmission of eating disorder behaviours. 母亲的饮食失调史和婴儿进餐时母亲和婴儿对食物的关注:饮食失调行为代际传递的候选因素。
Pub Date : 2026-01-16 eCollection Date: 2025-01-01 DOI: 10.3389/frcha.2025.1699643
Fay Huntley, Rebecca M Pearson, Ilaria Constantini, Marc H Bornstein, Amy Campbell, Miguel Cordero, Nicky Wright
<p><strong>Introduction: </strong>There is evidence to suggest that individuals with eating disorders (EDs) show differences in attention to food compared to those without eating disorders. Children of mothers with eating disorders are at an elevated risk of developing an eating disorder themselves. One potential intergenerational pathway may be that parents, and then infants, pay more attention to food in interactions, which in turn mediates transmission of disordered eating behaviours, particularly those during feeding and mealtimes. No study has investigated whether mothers' ED behaviour history is associated with maternal and infant attention to food during infant feeding interactions.</p><p><strong>Methods: </strong>Mothers and 7-month-old infants from the Avon Longitudinal Study of Parents and Children Generation-2 provided video footage of mother-infant feeding interactions filmed at home using head cameras. Feeding interactions were coded for mothers' and infants' visual attention using a micro-behavioural observational coding system. Outcomes were the mothers' and infants' proportion duration (of the entire feeding interaction) spent looking at food. Mothers' ED behaviour history was assessed at age 25 years using the Youth Risk Behaviour Surveillance System questionnaire, from which a binary Diagnostic and Statistical Manual of Mental Disorders, fifth edition, disordered eating variable was generated. Linear regression testing associations between mothers' ED behaviour history and mother and infant attention to food were adjusted for infants' sex, age, and birth order, and mothers' age, education, and employment.</p><p><strong>Results: </strong>In 98 mother-infant dyads, mothers' ED behaviour history was associated with longer proportion duration of infants' looking at food during mealtimes [estimate = 0.59 (0.19, 0.99), <i>p</i> = 0.004], corresponding to a 20% difference in time spent looking at food for infants of mothers with an ED behaviour history compared to those without. There was no association between ED behaviour history and mothers' attention to food.</p><p><strong>Conclusions: </strong>Increased infant looking time to food during feeding may indicate a preoccupation with food. This preoccupation could be a reflection of ED behaviours being modelled to offspring by mothers or early behavioural markers of shared genetic risk for EDs. Support for mother-infant dyads with an ED history could target guiding mothers' and infants' attention (via video feedback, for example) to non-food-related activities to minimise any impact on the mothers' relationship with the infant or the infants' relationship with food.</p><p><strong>Lay summary: </strong>Children of mothers with EDs are at an elevated risk of developing an eating disorder themselves. One potential pathway of transmission of eating disordered behaviour from mother to offspring may be through behaviours shown during feeding and mealtimes. Existing evidence suggests that ind
有证据表明,与没有饮食失调的人相比,饮食失调症患者对食物的注意力存在差异。患有饮食失调症的母亲所生的孩子自身患上饮食失调症的风险也较高。一个潜在的代际途径可能是父母,然后是婴儿,在互动中更关注食物,这反过来又介导了饮食失调行为的传播,特别是在喂食和用餐时间。没有研究调查母亲的ED行为史是否与母亲和婴儿在婴儿喂养互动中对食物的关注有关。方法:雅芳父母与儿童纵向研究第2代的母亲和7个月大的婴儿提供了在家中使用头部摄像机拍摄的母婴喂养互动视频片段。使用微行为观察编码系统对母亲和婴儿的视觉注意进行喂养互动编码。结果是母亲和婴儿(在整个喂养互动中)花在看食物上的时间比例。使用青少年风险行为监测系统问卷对母亲25岁时的ED行为史进行评估,从中产生了《精神障碍诊断与统计手册》第五版,饮食失调变量。根据婴儿的性别、年龄、出生顺序、母亲的年龄、教育程度和就业情况,对母亲ED行为史与母婴食物注意力之间的线性回归检验进行了调整。结果:在98对母婴中,母亲的ED行为史与婴儿在用餐时间看食物的时间比例较长有关[估计值= 0.59 (0.19,0.99),p = 0.004],对应于有ED行为史的母亲的婴儿看食物的时间与没有ED行为史的母亲的婴儿相比有20%的差异。ED行为史与母亲对食物的关注之间没有关联。结论:喂养期间婴儿看食物的时间增加可能表明对食物的关注。这种关注可能是ED行为被母亲模仿给后代的反映,或者是共享ED遗传风险的早期行为标记。对有ED病史的母婴的支持可以针对引导母亲和婴儿的注意力(例如通过视频反馈)到与食物无关的活动,以尽量减少对母亲与婴儿关系或婴儿与食物关系的影响。总结:患有急症的母亲的孩子患饮食失调的风险更高。饮食失调行为从母亲传给后代的一个潜在途径可能是在喂食和用餐时表现出的行为。现有证据表明,与没有饮食失调的人相比,饮食失调的人对食物的注意力有所不同,但没有研究调查过母婴互动中对食物的注意力。通过对在家喂养的自然观察,我们发现有饮食失调史的母亲的婴儿在吃饭时对食物的注意力增加了。这提供了初步的证据,喂食互动过程中的注意模式可能是干预的合理目标。
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引用次数: 0
What school-based interventions work to improve attendance in secondary school students with persistent absence? A systematic review. 哪些以学校为本的干预措施可以改善持续缺勤的中学生的出勤率?系统回顾。
Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frcha.2025.1603680
Alice Middleton, Martha Watson, Joanna K Anderson

Background: Absence from school is an increasing concern internationally, with significant consequences for children's mental health, academic achievement, and future opportunities. The multifaceted causes of absenteeism, including factors like emotionally based school avoidance (EBSA), have prompted a variety of interventions aimed at addressing this complexity. These efforts include recent plans from the UK government. This systematic review evaluates the effectiveness of school-based interventions targeting persistently absent secondary school students, to inform evidence-based strategies.

Methods: A systematic search was conducted across six electronic databases in health and education for studies published up to April 2024. Eligible studies assessed school-based interventions aimed at improving attendance among persistently absent secondary school students. The Effective Public Health Practice Project (EPHPP) and Critical Appraisal Skills Programme (CASP) tools were used to assess study quality. A bioecological framework was applied to map interventions to influence levels and evaluate their impact on attendance.

Results: Sixteen studies, mostly from the United States with one from Australia, were included. Study designs varied, including randomised controlled trials, quasi-experimental designs, and cohort studies, with quality ratings from weak to moderate. Interventions demonstrated variable effectiveness, reflecting the challenges of addressing persistent absenteeism. Favourable outcomes were reported for mentoring schemes, family involvement initiatives, school counselling, incentive programmes, school-based healthcare, and a police partnership strategy. However, inconsistencies in significance and impact were observed across studies.

Conclusion: The evidence base for interventions to improve attendance among persistently absent secondary school students remains limited. High-quality research is needed to build robust evidence, incorporating comprehensive attendance metrics alongside academic and health outcomes. Future studies should document and analyse demographic subgroups and include qualitative approaches to address the needs of diverse at-risk groups and guide intervention design.

Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024490992, PROSPERO [CRD42024490992].

背景:缺课是一个日益受到国际关注的问题,对儿童的心理健康、学业成绩和未来机会都有重大影响。旷课的原因是多方面的,包括情绪性逃避学校(EBSA)等因素,这促使了各种旨在解决这一复杂性的干预措施。这些努力包括英国政府最近的计划。本系统综述评估了针对持续缺课中学生的学校干预措施的有效性,为循证策略提供信息。方法:对截至2024年4月发表的6个健康与教育电子数据库进行系统检索。合格的研究评估了以学校为基础的干预措施,旨在提高持续缺课的中学生的出勤率。使用有效公共卫生实践项目(EPHPP)和关键评估技能计划(CASP)工具评估研究质量。应用生物生态框架绘制影响水平的干预措施图,并评估其对出席率的影响。结果:纳入了16项研究,其中大部分来自美国,1项来自澳大利亚。研究设计多种多样,包括随机对照试验、准实验设计和队列研究,质量评级从弱到中等。干预措施显示出不同的效果,反映了解决持续缺勤问题的挑战。据报告,指导计划、家庭参与倡议、学校咨询、奖励方案、学校医疗保健和警察伙伴关系战略取得了良好的成果。然而,在不同的研究中观察到重要性和影响的不一致性。结论:干预措施改善持续缺课中学生出勤率的证据基础仍然有限。需要进行高质量的研究,以建立强有力的证据,将全面的出勤指标与学术和健康结果结合起来。未来的研究应记录和分析人口亚组,并包括定性方法,以解决不同风险群体的需求,并指导干预设计。系统评价注册:https://www.crd.york.ac.uk/PROSPERO/view/CRD42024490992, PROSPERO [CRD42024490992]。
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引用次数: 0
Investigating the ADOS-2 calibrated severity score: insights from the ELENA cohort. 调查ADOS-2校准的严重程度评分:来自ELENA队列的见解。
Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frcha.2025.1674226
Hugo Peyre, Amaria Baghdadli

Introduction: The Autism Diagnostic Observation Schedule (ADOS-2) is widely used to assess Autism Spectrum Disorder (ASD) symptom severity. To allow comparisons across modules and developmental levels, the Calibrated Severity Score (ADOS-CSS) was developed. However, concerns have been raised about potential changes in the measurement signal introduced by the calibration process, which may alter the signal captured by the ADOS-2 raw scores (ADOS-RS).

Methods: Using longitudinal data from the ELENA cohort (N = 145 children with ASD assessed at baseline and after 3 years), we examined the psychometric properties of the ADOS-CSS and ADOS-RS. The Social Responsiveness Scale (SRS-2) was used as an external reference. Bootstrap resampling was used to estimate means and 95% confidence intervals (CIs).

Results: Variance explained by module, age, and IQ was higher for the ADOS-RS (R2 = 0.45, 95% CI: 0.38-0.52) than for the ADOS-CSS (R2 = 0.16, 95% CI: 0.10-0.24). Stability of ASD severity scores over time was lower for the ADOS-CSS (ρ = 0.34, 95% CI: 0.23-0.45) than for the ADOS-RS (ρ = 0.60, 95% CI: 0.51-0.68). Correlations with SRS-2 scores were consistently lower for ADOS-CSS (ρ = 0.14, 95% CI: 0.06-0.22) than for ADOS-RS (ρ = 0.24, 95% CI: 0.17-0.32). Similar patterns were observed for change scores (Δ indicating score differences between baseline and follow-up): ΔSRS-2 correlated more strongly with ΔADOS-RS (ρ = 0.19, 95% CI: 0.09-0.28) than with ΔADOS-CSS (ρ = 0.13, 95% CI: 0.06-0.21). Differences between ADOS modules were reflected in SRS-2 and ADOS-RS, but markedly attenuated in ADOS-CSS, suggesting that calibration reduces module-related variance but also induces changes in the measurement signal that may affect sensitivity to individual differences.

Discussion: While the ADOS-CSS facilitates standardized comparisons across modules, clinicians and researchers should be aware of potential distortions in the measurement signal associated with the calibration process.

Clinical trial registration: NCT02625116.

自闭症诊断观察量表(ADOS-2)被广泛用于评估自闭症谱系障碍(ASD)症状的严重程度。为了在模块和发展水平之间进行比较,开发了校准严重性评分(ADOS-CSS)。然而,人们担心校准过程中测量信号的潜在变化,这可能会改变由ADOS-2原始分数(ADOS-RS)捕获的信号。方法:使用来自ELENA队列(N = 145名ASD儿童,基线和3年后评估)的纵向数据,我们检查了ADOS-CSS和ADOS-RS的心理测量特性。采用社会反应性量表(SRS-2)作为外部参考。用Bootstrap重抽样来估计平均值和95%置信区间(ci)。结果:由模块、年龄和智商解释的方差在ADOS-RS组(R2 = 0.45, 95% CI: 0.38-0.52)高于ADOS-CSS组(R2 = 0.16, 95% CI: 0.10-0.24)。ADOS-CSS的ASD严重程度评分随时间的稳定性(ρ = 0.34, 95% CI: 0.23-0.45)低于ADOS-RS (ρ = 0.60, 95% CI: 0.51-0.68)。ADOS-CSS与SRS-2评分的相关性始终低于ADOS-RS (ρ = 0.14, 95% CI: 0.06-0.22) (ρ = 0.24, 95% CI: 0.17-0.32)。在变化评分中也观察到类似的模式(Δ表示基线和随访之间的评分差异):ΔSRS-2与ΔADOS-RS (ρ = 0.19, 95% CI: 0.09-0.28)的相关性强于与ΔADOS-CSS (ρ = 0.13, 95% CI: 0.06-0.21)的相关性。ADOS模块之间的差异在SRS-2和ADOS- rs中有所体现,但在ADOS- css中明显减弱,这表明校准降低了模块相关方差,但也引起了测量信号的变化,这可能会影响对个体差异的敏感性。讨论:虽然ADOS-CSS促进了模块间的标准化比较,但临床医生和研究人员应该意识到与校准过程相关的测量信号中的潜在失真。临床试验注册:NCT02625116。
{"title":"Investigating the ADOS-2 calibrated severity score: insights from the ELENA cohort.","authors":"Hugo Peyre, Amaria Baghdadli","doi":"10.3389/frcha.2025.1674226","DOIUrl":"10.3389/frcha.2025.1674226","url":null,"abstract":"<p><strong>Introduction: </strong>The Autism Diagnostic Observation Schedule (ADOS-2) is widely used to assess Autism Spectrum Disorder (ASD) symptom severity. To allow comparisons across modules and developmental levels, the Calibrated Severity Score (ADOS-CSS) was developed. However, concerns have been raised about potential changes in the measurement signal introduced by the calibration process, which may alter the signal captured by the ADOS-2 raw scores (ADOS-RS).</p><p><strong>Methods: </strong>Using longitudinal data from the ELENA cohort (<i>N</i> = 145 children with ASD assessed at baseline and after 3 years), we examined the psychometric properties of the ADOS-CSS and ADOS-RS. The Social Responsiveness Scale (SRS-2) was used as an external reference. Bootstrap resampling was used to estimate means and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>Variance explained by module, age, and IQ was higher for the ADOS-RS (R<sup>2</sup> = 0.45, 95% CI: 0.38-0.52) than for the ADOS-CSS (R<sup>2</sup> = 0.16, 95% CI: 0.10-0.24). Stability of ASD severity scores over time was lower for the ADOS-CSS (<i>ρ</i> = 0.34, 95% CI: 0.23-0.45) than for the ADOS-RS (<i>ρ</i> = 0.60, 95% CI: 0.51-0.68). Correlations with SRS-2 scores were consistently lower for ADOS-CSS (<i>ρ</i> = 0.14, 95% CI: 0.06-0.22) than for ADOS-RS (<i>ρ</i> = 0.24, 95% CI: 0.17-0.32). Similar patterns were observed for change scores (Δ indicating score differences between baseline and follow-up): ΔSRS-2 correlated more strongly with ΔADOS-RS (<i>ρ</i> = 0.19, 95% CI: 0.09-0.28) than with ΔADOS-CSS (<i>ρ</i> = 0.13, 95% CI: 0.06-0.21). Differences between ADOS modules were reflected in SRS-2 and ADOS-RS, but markedly attenuated in ADOS-CSS, suggesting that calibration reduces module-related variance but also induces changes in the measurement signal that may affect sensitivity to individual differences.</p><p><strong>Discussion: </strong>While the ADOS-CSS facilitates standardized comparisons across modules, clinicians and researchers should be aware of potential distortions in the measurement signal associated with the calibration process.</p><p><strong>Clinical trial registration: </strong>NCT02625116.</p>","PeriodicalId":73074,"journal":{"name":"Frontiers in child and adolescent psychiatry","volume":"4 ","pages":"1674226"},"PeriodicalIF":0.0,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12833228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146069178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of post-traumatic stress disorder and its association with adverse childhood experiences among refugee and host-community children and adolescents in Jordan. 约旦难民和收容社区儿童和青少年中创伤后应激障碍的患病率及其与不良童年经历的关系
Pub Date : 2026-01-12 eCollection Date: 2025-01-01 DOI: 10.3389/frcha.2025.1648195
Sara Abu Khudair, Yousef Khader, Osama Al Kouri, Mohannad Al Nsour, Eizaburo Tanaka

Background: Exposure to adverse childhood experiences (ACEs) is linked to the development of various psychological disorders, particularly post-traumatic stress disorder (PTSD). This study aimed to determine the prevalence rates of ACEs and high PTSD symptoms and to investigate their association among children and adolescents in Jordan.

Methods: A large-scale school-based national survey was conducted among children and adolescents in the host and refugee populations aged 8-18 years in Jordan, utilizing a multi-stage stratified cluster sampling technique. The study questionnaires contained standardized and psychometrically validated instruments to assess ACEs and PTSD.

Results: A total of 8,000 children and adolescents were included. The most prevalent ACEs among children were COVID-19 infection (43.2%), food insecurity or inadequate clothing (22.1%), and exam failure (21.7%), while for adolescents, COVID-19 infection (60.3%), exam failure (43.2%), and the death of a family member (31.7%). High PTSD symptoms were observed in 31.4%, more prevalent in females than males (33.0% vs. 29.3%, p = 0.003) and adolescents than children (35.5% vs. 24.6%, p < 0.001). For both children and adolescents, feeling unloved by family was significantly associated with high PTSD symptoms (OR = 2.1, p < 0.001). Other significant ACEs included death of a family member (children: OR = 1.9; adolescents: OR = 1.8) and food insecurity/inadequate clothing (OR = 1.7 for both). In children, exam failure was significant (OR = 1.5), while in adolescents, it included physical assault (OR = 1.4), COVID-19 infection (OR = 1.3), serious accidents (OR = 1.3), and emotional abuse (OR = 1.6). Experiencing ≥4 ACEs greatly increased PTSD odds (children: OR = 5.0, adolescents: OR = 4.3; p < 0.001).

Conclusion: Findings highlight a high prevalence of PTSD among children and adolescents exposed to ACEs, with multiple ACEs linked to higher PTSD symptoms and a cumulative pattern further increasing this risk. Results underscore the need for targeted interventions addressing key ACEs by age group and the development of comprehensive prevention programs involving parents, families, schools, communities, and broader society. Interventions should also aim to mitigate the cumulative impact of multiple ACEs and address them collectively rather than individually.

背景:童年不良经历(ace)暴露与各种心理障碍,特别是创伤后应激障碍(PTSD)的发展有关。本研究旨在确定ace和高PTSD症状的患病率,并调查其在约旦儿童和青少年中的相关性。方法:采用多阶段分层整群抽样技术,对约旦8-18岁的收容和难民人口中的儿童和青少年进行了大规模的全国性学校调查。研究问卷包含标准化和心理计量学验证的工具来评估ace和PTSD。结果:共纳入8000名儿童和青少年。儿童中最常见的ace是COVID-19感染(43.2%)、食物不安全或衣服不足(22.1%)和考试不及格(21.7%),而青少年中最常见的ace是COVID-19感染(60.3%)、考试不及格(43.2%)和家庭成员死亡(31.7%)。高PTSD症状发生率为31.4%,女性高于男性(33.0%比29.3%,p = 0.003),青少年高于儿童(35.5%比24.6%,p = 0.003)。结论:研究结果强调暴露于ace的儿童和青少年中PTSD的患病率较高,多次ace与高PTSD症状相关,且累积模式进一步增加了这种风险。研究结果强调,需要针对不同年龄组的主要不良反应采取有针对性的干预措施,并制定涉及家长、家庭、学校、社区和更广泛社会的综合预防方案。干预措施还应旨在减轻多重不良行为的累积影响,并共同解决这些问题,而不是单独解决。
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引用次数: 0
Parental concerns correspond to earliest age of autism diagnosis in increased likelihood infant cohort. 在增加的婴儿队列中,父母的关注与自闭症诊断的最早年龄相对应。
Pub Date : 2026-01-07 eCollection Date: 2025-01-01 DOI: 10.3389/frcha.2025.1722543
Kal Clintberg, Lori-Ann R Sacrey, Lonnie Zwaigenbaum, Jessica A Brian, Peter Szatmari, Tracy Vaillancourt

Autism spectrum disorder (ASD) encompasses a set of behavioural features with a diverse range of presentations, challenges, and trajectories. Previous research has demonstrated how behavioural and developmental markers can differentiate autistic from non-autistic children as early as the first year of life, however there is a dearth of literature demonstrating heterogeneity amongst the clinical presentations of autistic infants. An understanding of the breadth of experiences is necessary to refine and expand early identification methods to identify those currently being overlooked. The current study examined the heterogeneity of early behaviour in a longitudinal cohort of infant siblings of autistic children (n = 72) who later received an ASD diagnosis. Parent reports of early behaviour, generated at six time points between six and 24 months of age, describing the presence or absence of concerns across 10 developmental domains, were assessed to compare subgroups of infants based on the earliest age they were diagnosed as autistic (18, 24, or 36 months). The average number of concerns across domains, in addition to the proportion of each subgroup reporting a concern in each of the 10 domains, was compared at each time point. The infants diagnosed at 18 months had a higher average number of concerns across all time points compared to those diagnosed at 24 or 36 months, who demonstrated similar profiles. Play, language, and language regression concerns resulted in the largest effect sizes between groups. These findings indicate that (i) there is heterogeneity in early autism presentations, (ii) within the context of early identification, lack of diagnosis at one age does not eliminate the possibility of future diagnosis, and (iii) that parent reports of early concerns can provide valuable information that can alert clinicians to the features of autism, further attention to which may help reduce disparities in age of diagnosis.

自闭症谱系障碍(ASD)包括一系列具有不同表现、挑战和轨迹的行为特征。先前的研究已经证明了行为和发育标记如何能够早在一岁的时候就将自闭症儿童与非自闭症儿童区分开来,然而,缺乏证明自闭症婴儿临床表现异质性的文献。了解经验的广度对于改进和扩展早期识别方法以识别目前被忽视的方法是必要的。目前的研究调查了自闭症儿童的兄弟姐妹(n = 72)的纵向队列中早期行为的异质性,这些儿童后来接受了ASD诊断。在6至24个月大的6个时间点产生的早期行为的父母报告,描述了10个发展领域中存在或不存在的问题,根据他们被诊断为自闭症的最早年龄(18、24或36个月),对这些报告进行了评估,以比较婴儿亚组。在每个时间点比较跨领域的关注的平均数量,以及在10个领域中报告关注的每个子组的比例。与24或36个月确诊的婴儿相比,18个月确诊的婴儿在所有时间点上都有更高的平均担忧次数,这两个时间点表现出相似的特征。游戏、语言和语言回归是组间最大的影响因素。这些发现表明:(1)自闭症早期表现存在异质性;(2)在早期识别的背景下,在一个年龄缺乏诊断并不排除未来诊断的可能性;(3)父母早期关注的报告可以提供有价值的信息,可以提醒临床医生注意自闭症的特征,进一步关注这些特征可能有助于减少诊断年龄的差异。
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引用次数: 0
Efficacy and safety of atomoxetine in the treatment of ADHD in children and adolescents: a systematic review. 托莫西汀治疗儿童和青少年多动症的有效性和安全性:一项系统综述。
Pub Date : 2026-01-06 eCollection Date: 2025-01-01 DOI: 10.3389/frcha.2025.1731330
Edmundo Alberto Barbosa Bastos De Souza Neto, Halley Ferraro Oliveira, Williams Santos Ramos, Estelio Henrique Martin Dantas, Barbara Hellen Alves Pereira, Rebeca de Souza Mariano Bastos

Objective: To evaluate the efficacy and safety of atomoxetine in the treatment of adolescents with ADHD, comparing its effects with other available treatments. The primary outcome was the reduction of ADHD symptoms, and the secondary outcome was the occurrence of adverse effects.

Methods: A search was conducted in the Medline/PubMed, EMBASE, and Web of Science databases. The research question and strategy were based on the PICO model. Inclusion criteria were restricted to studies involving children and adolescents aged 6-16 years, focusing on comparisons between atomoxetine and other treatments. Eligible studies were published in English, Spanish, or Portuguese, with no restrictions on publication year. A total of 575 articles were initially retrieved. After removing duplicates, 527 references were screened by title and abstract, and 69 were selected for full-text review. Following this stage, 63 references were excluded, and 6 studies were ultimately deemed eligible.

Results: The six included studies involved a total of 905 participants. Atomoxetine demonstrated comparable efficacy to methylphenidate in reducing ADHD symptoms. The most common adverse effects were nausea, fatigue, and appetite changes. No severe adverse events were consistently reported. Atomoxetine's efficacy was particularly evident in patients who did not tolerate or respond to stimulant medications.

Conclusion: Available evidence suggests that atomoxetine is an effective and safe option for treating ADHD in adolescents, representing a valid alternative particularly for patients who do not tolerate stimulant medications. Continued research, especially long-term studies, is necessary to confirm its efficacy across different patient subgroups.

Systematic review registration: Identifier CRD420251152121.

目的:评价托莫西汀治疗青少年多动症的疗效和安全性,并与其他现有治疗方法进行比较。主要结局是ADHD症状的减轻,次要结局是不良反应的发生。方法:在Medline/PubMed、EMBASE和Web of Science数据库中进行检索。研究的问题和策略是基于PICO模型的。纳入标准仅限于涉及6-16岁儿童和青少年的研究,重点是托莫西汀与其他治疗的比较。符合条件的研究以英语、西班牙语或葡萄牙语发表,对发表年份没有限制。最初共检索了575篇文章。剔除重复文献后,按标题和摘要筛选527篇文献,选择69篇文献进行全文评审。在此阶段之后,63篇文献被排除,6项研究最终被认为符合条件。结果:六项纳入的研究共涉及905名参与者。托莫西汀在减轻ADHD症状方面显示出与哌醋甲酯相当的疗效。最常见的不良反应是恶心、疲劳和食欲改变。没有严重不良事件的持续报道。托莫西汀的疗效在对兴奋剂药物无耐受或无反应的患者中尤为明显。结论:现有证据表明,托莫西汀是治疗青少年多动症的一种有效且安全的选择,特别是对于不能耐受兴奋剂药物的患者来说,是一种有效的选择。需要继续研究,特别是长期研究,以确认其对不同患者亚组的疗效。系统评价注册:标识符CRD420251152121。
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引用次数: 0
The role of social support in moderating the impact of cumulative trauma on suicidal thoughts and behaviors. 社会支持在缓解累积性创伤对自杀念头和行为的影响中的作用。
Pub Date : 2025-12-09 eCollection Date: 2025-01-01 DOI: 10.3389/frcha.2025.1677475
Martine Hébert, Amélie Tremblay-Perreault, Laetitia Mélissande Amédée

Introduction: Suicidality in adolescence is a significant public health concern. One potential correlate of suicidality is exposure to childhood trauma. Research shows that cumulative trauma is associated with a higher risk of suicidality during adolescence, with a dose-response pattern between the number of adversities and suicidal outcomes. However, not all adolescents exposed to adversity report suicidal thoughts or behaviors, suggesting that protective factors, such as social support, may buffer this association. This cross-sectional study examined gender differences in the prevalence of suicidal thoughts and behaviors, cumulative trauma, and social support among high school students. The study also sought to determine whether cumulative trauma was related to an increased likelihood of suicidal thoughts and behaviors, and whether social support moderated the association.

Methods: Data were collected from a representative sample of 8,194 adolescents in Grades 9-11 in Quebec, Canada.

Results: Girls were more likely than boys to report both suicidal ideation and attempts. The number of traumas experienced was positively associated with the prevalence of suicidal ideation and attempts, with each additional trauma linked to an estimated 65%-80% increase in odds, indicating a large dose-response association. After controlling for sociodemographic characteristics, social support was associated with an attenuation of the relationship between cumulative trauma and suicidal ideation. For suicide attempts, social support showed a direct protective effect among adolescent girls, but this association was not observed among boys.

Discussion: These findings highlight the relevance of early identification and support services for youth reporting multiple adversities and lower social support.

青少年自杀是一个重要的公共卫生问题。自杀的一个潜在关联是暴露在童年创伤中。研究表明,在青少年时期,累积性创伤与较高的自杀风险有关,在逆境数量和自杀结果之间存在剂量-反应模式。然而,并非所有遭遇逆境的青少年都有自杀的想法或行为,这表明保护因素,如社会支持,可能会缓冲这种联系。这项横断面研究调查了高中学生自杀想法和行为的流行程度、累积创伤和社会支持的性别差异。该研究还试图确定累积性创伤是否与自杀想法和行为的可能性增加有关,以及社会支持是否缓和了这种联系。方法:数据收集自加拿大魁北克省9-11年级8,194名青少年的代表性样本。结果:女孩比男孩更有可能报告自杀意念和企图。经历过创伤的数量与自杀意念和企图的流行率呈正相关,每增加一次创伤,自杀几率估计增加65%-80%,表明存在很大的剂量反应关系。在控制了社会人口学特征后,社会支持与累积创伤和自杀意念之间关系的衰减有关。对于自杀企图,社会支持在青春期女孩中显示出直接的保护作用,但在男孩中没有观察到这种联系。讨论:这些发现强调了早期识别和支持服务对报告多重逆境和较低社会支持的青年的相关性。
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引用次数: 0
Bridging the gap: a cross-cultural examination of PCIT training experiences across Black, White, Asian, and Multiracial clinicians. 弥合差距:黑人、白人、亚洲人和多种族临床医生的PCIT培训经验的跨文化检查。
Pub Date : 2025-12-08 eCollection Date: 2025-01-01 DOI: 10.3389/frcha.2025.1549333
Felipa T Chavez, Kaela Farrise Beauvoir, Eyram Agbeli, Sierra Coffey, Emily Aron, Erica E Coates

Introduction: Parent-Child Interaction Therapy (PCIT) is a strongly evidence-based treatment (EBT) for disruptive behaviors in young children. However, PCIT research with Black families has identified notable disparities particularly with regard to more frequent and earlier attrition from treatment and disparate outcomes. Prominent etiological explanations lie in PCIT's perception as a Eurocentric treatment embedded within discriminatory systems and, therefore, unable to meet Black families' unique cultural needs. The present study sought to better understand the training experiences of PCIT clinicians broadly, and with a specific eye towards illuminating the cultural congruence and incongruence of PCIT training towards the goal of serving Black families.

Methods: A racially diverse (Black n = 10; White n = 8; Asian n = 2; Multiracial n = 2) sample of PCIT clinicians (n = 22) was interviewed using a structured interview protocol. Transcripts from the virtual interviews were analyzed by a 4-person coding team using thematic analysis with both inductive and deductive code development. Clinicians were also administered a modified measure of self-perceived provider cultural competence. Independent samples t-tests were performed to compare perceptions of cultural competence among various racial groupings.

Results: Several themes were identified including a corroboration by clinicians across racial groups regarding perceptions of high-quality but very White-normed training experiences, the need for more Black PCIT clinicians, and inadequate preparation for tailoring PCIT towards Black families. Additionally, while other research suggests that Black clinicians feel adept at culturally interpreting certain PCIT language and larger concepts they deemed inappropriate for servicing Black families, current findings suggest that both White and Asian American clinicians reported less confidence in knowing how to address the unique needs of Black families with PCIT. Quantitatively, significant differences were found in the level of perceived cultural competence between White and non-White clinicians.

Discussion: Overall, this study highlights areas for growth in PCIT training and the development of a diverse body of PCIT clinicians able to meet the needs of Black families. Implications for clinical training development and implementation, as well as clinician recruitment and retention, are discussed.

亲子互动疗法(PCIT)是一种针对幼儿破坏性行为的强有力的循证治疗(EBT)。然而,针对黑人家庭的PCIT研究发现了显著的差异,特别是在更频繁和更早的治疗磨损和不同的结果方面。突出的病因解释在于PCIT被认为是一种嵌入歧视性制度中的以欧洲为中心的治疗,因此无法满足黑人家庭独特的文化需求。本研究旨在更广泛地了解PCIT临床医生的培训经验,并特别着眼于阐明PCIT培训与服务黑人家庭目标的文化一致性和不一致性。方法:采用结构化访谈方案对不同种族(黑人n = 10;白人n = 8;亚洲n = 2;多种族n = 2)的PCIT临床医生(n = 22)进行访谈。虚拟访谈记录由一个4人编码团队使用归纳和演绎代码开发的主题分析进行分析。临床医生也进行了自我感知提供者文化能力的改进措施。采用独立样本t检验比较不同种族群体对文化能力的认知。结果:确定了几个主题,包括不同种族的临床医生对高质量但非常白人规范的培训经验的看法的佐证,需要更多的黑人PCIT临床医生,以及为黑人家庭量身定制PCIT的准备不足。此外,虽然其他研究表明,黑人临床医生在文化上善于解释某些他们认为不适合为黑人家庭服务的PCIT语言和更大的概念,但目前的研究结果表明,白人和亚裔美国临床医生在了解如何解决患有PCIT的黑人家庭的独特需求方面缺乏信心。在数量上,在白人和非白人临床医生之间的感知文化能力水平上发现了显著差异。讨论:总的来说,本研究突出了PCIT培训的增长领域,以及能够满足黑人家庭需求的PCIT临床医生的多样化发展。对临床培训发展和实施的影响,以及临床医生的招聘和保留,进行了讨论。
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引用次数: 0
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Frontiers in child and adolescent psychiatry
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