Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1974.TB02288.X
S. Rosendal
A total of 118 mycoplasma strains isolated from the conjunctivae and the respiratory- and genital tracts of 78 dogs were studied biochemically and serologically. Three biochemical tests (glucose fermentation, catabolism of arginine and phosphatase activity) were found to be very useful for a preliminary biochemical grouping prior to serological identification. Using these tests, the strains could be divided into six groups that did not show any antigenic overlapping. By serological examination using the indirect immunofluorescence technique and growth inhibition 35 isolates were identified as M. canis; 21 were identified as M. edwardii; 10 as M. cynos; 10 as the feline species M. gateae; 30 as M. spumans; 2 as M. maculosum; 2 as the bovine species M. bovigenitalium; and 5 as M. feliminutum, a species previously represented by a single strain isolated from a cat. The three remaining strains which were glucose positive and arginine and phosphatase negative were placed in a separate serogroup, group A, as they were serologically different from the established canine species.
对78只犬结膜、呼吸道和生殖道分离的118株支原体进行了生化和血清学研究。三个生化测试(葡萄糖发酵,精氨酸分解代谢和磷酸酶活性)被发现对血清学鉴定之前的初步生化分组非常有用。通过这些测试,这些菌株可以分为六组,没有显示任何抗原重叠。采用间接免疫荧光技术和生长抑制技术进行血清学检测,鉴定35株分离株为犬支原体;鉴定为爱德华氏分枝杆菌21株;10 . M. cynos;10种为猫科动物门门门门;30例为M. spumans;2 . M. maculosum;2为牛种M. bovigenitalium;5个为猫分枝杆菌,该物种以前由从猫身上分离出来的单一菌株代表。其余三株葡萄糖阳性,精氨酸和磷酸酶阴性的菌株被放置在一个单独的血清组,a组,因为它们在血清学上与已建立的犬种不同。
{"title":"Canine mycoplasmas II: biochemical characterization and serological identification.","authors":"S. Rosendal","doi":"10.1111/J.1699-0463.1974.TB02288.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02288.X","url":null,"abstract":"A total of 118 mycoplasma strains isolated from the conjunctivae and the respiratory- and genital tracts of 78 dogs were studied biochemically and serologically. Three biochemical tests (glucose fermentation, catabolism of arginine and phosphatase activity) were found to be very useful for a preliminary biochemical grouping prior to serological identification. Using these tests, the strains could be divided into six groups that did not show any antigenic overlapping. By serological examination using the indirect immunofluorescence technique and growth inhibition 35 isolates were identified as M. canis; 21 were identified as M. edwardii; 10 as M. cynos; 10 as the feline species M. gateae; 30 as M. spumans; 2 as M. maculosum; 2 as the bovine species M. bovigenitalium; and 5 as M. feliminutum, a species previously represented by a single strain isolated from a cat. The three remaining strains which were glucose positive and arginine and phosphatase negative were placed in a separate serogroup, group A, as they were serologically different from the established canine species.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"10 1","pages":"25-32"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77446119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1974.TB02366.X
N. Høiby, L. Mathiesen
The influence of chronic Ps. aeruginosa infection on the occurrence of bone marrow-derived lymphocytes (B cells) and thymus-derived lymphocytes (T cells) in peripheral blood have been studied in 2 groups of patients with cystic fibrosis. One group (9 patients) suffered from chronic Ps. aeruginosa infection in the respiratory tract and produced multiple Ps. aeruginosa precipitins which were demonstrated by means of crossed immunoelectrophoresis. The other group (9 patients) had never harboured Ps. aeruginosa in the respiratory tract and presented no demonstrable precipitins against this bacteria. The lymphocytes were examined for the presence of 2 surface markers for B cells: receptor for C3 complement component (EAC rosette-formation) and surface immunoglobulins (immunofluorescent staining), and for the presence of 1 surface marker for T cells: spontaneous binding of sheep red blood cells (E rosette-formation). The B:T cell ratio was nearly identical in the 2 groups of patients whereas the total numbers of B and T cells were significant higher in patients with chronic Ps. aeruginosa infection. The number of Ps. aeruginosa precipitins per serum was significant positively correlated to the total number of T cells, wheras the correlation with the total number of B cells was insignificant.
{"title":"Pseudomonas aeruginosa infection in cystic fibrosis. Distribution of B and T lymphocytes in relation to the humoral immune response.","authors":"N. Høiby, L. Mathiesen","doi":"10.1111/J.1699-0463.1974.TB02366.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02366.X","url":null,"abstract":"The influence of chronic Ps. aeruginosa infection on the occurrence of bone marrow-derived lymphocytes (B cells) and thymus-derived lymphocytes (T cells) in peripheral blood have been studied in 2 groups of patients with cystic fibrosis. One group (9 patients) suffered from chronic Ps. aeruginosa infection in the respiratory tract and produced multiple Ps. aeruginosa precipitins which were demonstrated by means of crossed immunoelectrophoresis. The other group (9 patients) had never harboured Ps. aeruginosa in the respiratory tract and presented no demonstrable precipitins against this bacteria. The lymphocytes were examined for the presence of 2 surface markers for B cells: receptor for C3 complement component (EAC rosette-formation) and surface immunoglobulins (immunofluorescent staining), and for the presence of 1 surface marker for T cells: spontaneous binding of sheep red blood cells (E rosette-formation). The B:T cell ratio was nearly identical in the 2 groups of patients whereas the total numbers of B and T cells were significant higher in patients with chronic Ps. aeruginosa infection. The number of Ps. aeruginosa precipitins per serum was significant positively correlated to the total number of T cells, wheras the correlation with the total number of B cells was insignificant.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"33 1","pages":"559-566"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78371872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1974.TB02323.X
K. Mygind, S. Stenbjerg
The response of peripheral human leucocytes to PPD and tubercle bacilli was studied in the leucocyte migration test in agarose medium. At PPD 50 μg/ml migration of leucocytes from tuberculin positive persons was inhibited in all cases tested, while no migration inhibition of cells from tuberculin negative persons was found. There was no overlapping between the MI of the two groups. Blocking of protein synthesis by means of puromycin prevented the migration inhibition of cells from tuberculin positive persons at PPD 50 μg/ml and 100 μg/ml. In some cases the migration of cells from tuberculin negative persons was inhibited in the presence of PPD 100 μg/ml. This inhibition could not be prevented by puromycin and was probably due to a toxic effect of PPD. It is suggested that puromycin may be useful in dislocating false, probably toxic, inhibition.
{"title":"Leucocyte migration test in agarose. The use of puromycin in disclosure of non-immunological inhibition.","authors":"K. Mygind, S. Stenbjerg","doi":"10.1111/J.1699-0463.1974.TB02323.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02323.X","url":null,"abstract":"The response of peripheral human leucocytes to PPD and tubercle bacilli was studied in the leucocyte migration test in agarose medium. At PPD 50 μg/ml migration of leucocytes from tuberculin positive persons was inhibited in all cases tested, while no migration inhibition of cells from tuberculin negative persons was found. There was no overlapping between the MI of the two groups. Blocking of protein synthesis by means of puromycin prevented the migration inhibition of cells from tuberculin positive persons at PPD 50 μg/ml and 100 μg/ml. In some cases the migration of cells from tuberculin negative persons was inhibited in the presence of PPD 100 μg/ml. This inhibition could not be prevented by puromycin and was probably due to a toxic effect of PPD. It is suggested that puromycin may be useful in dislocating false, probably toxic, inhibition.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"25 1","pages":"277-82"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83303597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1970.TB04365.X
K. Fossum
{"title":"Proteolytic enzymes and biological inhibitors. 3. Naturally occurring inhibitors in some animal and plant materials and their effect upon proteolytic enzymes of various origin.","authors":"K. Fossum","doi":"10.1111/J.1699-0463.1970.TB04365.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1970.TB04365.X","url":null,"abstract":"","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"61 1","pages":"741-54"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79132837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1974.TB00242.X
L. Trier, B. Rubin
Lethally irradiated mice reconstituted with allogeneic bone marrow cells usually survive the irradiation damage, but their immune-status is not completely restored. Thus, such mice show depressed humoral antibody responses to thymus dependent antigens, prolonged allogeneic skin graft survival, and their spleen cells display reduced graft-versus-host (GVH) activity when inoculated into newborn F1 hybrid mice. The present study was carried out in order to explore the reason(s) for the depressed immunological activity of allogeneic irradiation chimaeric mice. It was found that these mice had an elevated level of θ positive cells compared to mice transplanted with syngeneic bone marrow cells, but their spleen cells did not show any detectable specific or third-party GVH response. Spleen cells from allogeneic irradiation chimaeras were not able to participate in a collaborative GVH response with lymph node cells either. Possible reasons for the immunological inertness of θ positive cells in allogeneic irradiation chimaeras are discussed.
{"title":"Bone marrow transplantation in inbred strains of mice. I. The failure of development of normal T cell function following allogeneic transplantation.","authors":"L. Trier, B. Rubin","doi":"10.1111/J.1699-0463.1974.TB00242.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB00242.X","url":null,"abstract":"Lethally irradiated mice reconstituted with allogeneic bone marrow cells usually survive the irradiation damage, but their immune-status is not completely restored. Thus, such mice show depressed humoral antibody responses to thymus dependent antigens, prolonged allogeneic skin graft survival, and their spleen cells display reduced graft-versus-host (GVH) activity when inoculated into newborn F1 hybrid mice. The present study was carried out in order to explore the reason(s) for the depressed immunological activity of allogeneic irradiation chimaeric mice. It was found that these mice had an elevated level of θ positive cells compared to mice transplanted with syngeneic bone marrow cells, but their spleen cells did not show any detectable specific or third-party GVH response. Spleen cells from allogeneic irradiation chimaeras were not able to participate in a collaborative GVH response with lymph node cells either. Possible reasons for the immunological inertness of θ positive cells in allogeneic irradiation chimaeras are discussed.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"113 1","pages":"724-32"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79191268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1970.TB04347.X
Kåre Fossum
{"title":"Proteolytic enzymes and biological inhibitors. II. Naturally occurring inhibitors in sera from different species and their effect upon proteolytic enzymes of various origin.","authors":"Kåre Fossum","doi":"10.1111/J.1699-0463.1970.TB04347.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1970.TB04347.X","url":null,"abstract":"","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"39 1","pages":"605-18"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78958971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1970.TB04279.X
K. Work, L. Eriksen, K. L. Fennestad, T. Moller, J. Siim
Six sows in the 3rd month of gestation were infected with Toxoplasma gondii, four intravenously with the RH strain, two perorally with a porcine strain. Severe disease, characterized by fever, anorexia and dyspnoea, was seen in the animals infected with the RH strain and one sow died on day 4. Mild febrile disease was seen in the porcine strain infections. Parasitaemia and Toxoplasma antibodies became demonstrable in all sows, and at term the sows delivered dead and/or live piglets, the mortality being 50–100 per cent in three RH strain infected litters and 30 per cent in one porcine strain infected litter. At sacrifice, Toxoplasma was found in the sows infected with the porcine strain but in none of those infected with the RH strain. Non-viable Toxoplasma was demonstrated histologically in 17 of 35 dead piglets and viable Toxoplasma was isolated from the cord blood of three liveborn piglets. At sacrifice 3–4 weeks after birth, Toxoplasma was demonstrable in several piglets from both sows infected with the porcine strain but in none of the piglets from sows infected with the RH strain. It is concluded that toxoplasmosis during the 3rd month of pregnancy in swine may cause fetal infection, resulting in death and congenital toxoplasmosis of liveborn piglets. Infection of the fetuses occurs probably during the maternal parasitaemia but horizontal infection i. e. from one litter mate to another, may also take place. There is little chance of isolating viable Toxoplasma from mummified or macerated fetuses, but non-viable Toxoplasma may be demonstrated by histological examination.
{"title":"Experimental toxoplasmosis in pregnant sows. I. Clinical, parasitological and serological observations.","authors":"K. Work, L. Eriksen, K. L. Fennestad, T. Moller, J. Siim","doi":"10.1111/J.1699-0463.1970.TB04279.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1970.TB04279.X","url":null,"abstract":"Six sows in the 3rd month of gestation were infected with Toxoplasma gondii, four intravenously with the RH strain, two perorally with a porcine strain. Severe disease, characterized by fever, anorexia and dyspnoea, was seen in the animals infected with the RH strain and one sow died on day 4. Mild febrile disease was seen in the porcine strain infections. Parasitaemia and Toxoplasma antibodies became demonstrable in all sows, and at term the sows delivered dead and/or live piglets, the mortality being 50–100 per cent in three RH strain infected litters and 30 per cent in one porcine strain infected litter. At sacrifice, Toxoplasma was found in the sows infected with the porcine strain but in none of those infected with the RH strain. Non-viable Toxoplasma was demonstrated histologically in 17 of 35 dead piglets and viable Toxoplasma was isolated from the cord blood of three liveborn piglets. At sacrifice 3–4 weeks after birth, Toxoplasma was demonstrable in several piglets from both sows infected with the porcine strain but in none of the piglets from sows infected with the RH strain. It is concluded that toxoplasmosis during the 3rd month of pregnancy in swine may cause fetal infection, resulting in death and congenital toxoplasmosis of liveborn piglets. Infection of the fetuses occurs probably during the maternal parasitaemia but horizontal infection i. e. from one litter mate to another, may also take place. There is little chance of isolating viable Toxoplasma from mummified or macerated fetuses, but non-viable Toxoplasma may be demonstrated by histological examination.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"21 1","pages":"129-39"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90401021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1974.TB02339.X
G. Asbjørnsen
{"title":"The effect of different serum concentrations of antimicrobial agents on the Lactobacillus casei folate assay.","authors":"G. Asbjørnsen","doi":"10.1111/J.1699-0463.1974.TB02339.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02339.X","url":null,"abstract":"","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"16 1","pages":"371-4"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79279172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1970.TB04366.X
K. Fossum
{"title":"Proteolytic enzymes and biological inhibitors. IV. Bacterial proteinase inhibitors and their effect upon enzymes of various origin.","authors":"K. Fossum","doi":"10.1111/J.1699-0463.1970.TB04366.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1970.TB04366.X","url":null,"abstract":"","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"2 1","pages":"755-9"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72837526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-08-15DOI: 10.1111/J.1699-0463.1974.TB02387.X
S. Jyssum
Whole cells of Neisseria meningitidis are found to utilize exogenous radioactive adenosine with labelling of the adenine, adenosine 5′-monophosphate, adenosine 5′-diphosphate and adenosine 5′-triphosphate pools. Extracts from N. meningitidis were found to have activities corresponding to adenosine nucleosidase (EC 3.2.2.7). No activities corresponding to purinenucleoside phosphorylase (EC 2.4.2.1), adenosine kinase (EC 2.7.1.20) or adenosine deaminase (EC 3.5.4.4) could be demonstrated. Radioactive guanosine or inosine were not found to be utilized by whole cells. A hydrolytic breakdown of guanosine or inosine to guanine and ribose, respectively hypoxanthine and ribose could not be demonstrated in crude extracts. Likewise, the search for activities corresponding to a guanosine kinase or to inosine kinase (EC 2.7.1.73) was altogether negative.
{"title":"Purine metabolism in Neisseria meningitidis. 2. Utilization of exogenous adenosine, guanosine and inosine.","authors":"S. Jyssum","doi":"10.1111/J.1699-0463.1974.TB02387.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB02387.X","url":null,"abstract":"Whole cells of Neisseria meningitidis are found to utilize exogenous radioactive adenosine with labelling of the adenine, adenosine 5′-monophosphate, adenosine 5′-diphosphate and adenosine 5′-triphosphate pools. Extracts from N. meningitidis were found to have activities corresponding to adenosine nucleosidase (EC 3.2.2.7). No activities corresponding to purinenucleoside phosphorylase (EC 2.4.2.1), adenosine kinase (EC 2.7.1.20) or adenosine deaminase (EC 3.5.4.4) could be demonstrated. Radioactive guanosine or inosine were not found to be utilized by whole cells. A hydrolytic breakdown of guanosine or inosine to guanine and ribose, respectively hypoxanthine and ribose could not be demonstrated in crude extracts. Likewise, the search for activities corresponding to a guanosine kinase or to inosine kinase (EC 2.7.1.73) was altogether negative.","PeriodicalId":7323,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology","volume":"52 1","pages":"885-94"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91020763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}