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International journal of dermatology and venereology最新文献

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Eruptive Cutaneous Collagenoma: Report of Two Cases 爆发性皮肤胶原瘤:两个病例的报告
Pub Date : 2020-05-14 DOI: 10.1097/JD9.0000000000000103
Jian Wu, Meihong Cai, Lingling Chen, Lei Wu, Xiaojian Chen, Hong-Yan Zhu, Feng Shi
Abstract Introduction: Eruptive cutaneous collagenoma is non familial connective tissue nevi of unknown etiology presented with an abrupt onset. To date, the literatures on eruptive cutaneous collagenoma are extremely rare in china. Here, we report two women with eruptive cutaneous collagenoma. Case present: Two women presented with multiple asymptomatic, skin-colored papules and nodules on the trunk and extremities with no systemic involvement. Histopathology revealed dense, coarse collagen fibers by hematoxylin-esoin stain and decreased, fragmented elastic fibers by Elastic stain compared with the normal skin. Basing on these findings, the diagnosis of eruptive cutaneous collagenoma was made. No specific treatment was given. Discussion: Eruptive cutaneous collagenoma is a very rare dermatosis that is often misdiagnosed as other connective tissue nevi. The pathogenesis is unclear, and also no efficient treatment is available. It is usually diagnosed based on clinical and histopathological findings. Conclusion: The present cases are relatively rare type of eruptive cutaneous collagenoma that provide more experience for clinician, and may be helpful for them to make correct diagnosis for suspicious cases.
摘要 简介:爆发性皮肤胶原瘤是一种病因不明的非家族性结缔组织痣,发病突然。迄今为止,有关爆发性皮肤胶原瘤的文献在中国极为罕见。在此,我们报告了两名患有爆发性皮肤胶原瘤的女性患者。病例介绍两名女性患者在躯干和四肢出现多个无症状的皮肤色丘疹和结节,无全身受累。组织病理学检查发现,与正常皮肤相比,苏木精-伊红染色显示胶原纤维致密、粗糙,弹性染色显示弹性纤维减少、碎裂。根据这些结果,诊断为爆发性皮肤胶原瘤。未给予特殊治疗。讨论爆发性皮肤胶原瘤是一种非常罕见的皮肤病,常被误诊为其他结缔组织痣。其发病机制尚不清楚,也没有有效的治疗方法。通常根据临床和组织病理学结果进行诊断。结论本病例是相对罕见的爆发性皮肤胶原瘤,为临床医生提供了更多经验,有助于他们对可疑病例做出正确诊断。
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引用次数: 0
Complete Draft Genome Sequence of Cutibacterium (Propionibacterium) acnes Type Strain ATCC6919 痤疮丙酸杆菌(Cutibacterium (Propionibacterium) acnes)型菌株 ATCC6919 的完整基因组序列草案
Pub Date : 2020-05-12 DOI: 10.1097/JD9.0000000000000096
H. Tang, Kaiwei Si, Xiao Zhang, Heling Zhu, Wenliang Zheng, Xibao Zhang, Jingyao Liang, J. Ruan
Objectives: The wide use of antibiotics for acne is the main cause of drug-resistantCutibacterium acnes. However, the complete genetic sequence reference of C. acnes has not yet been reported. Herein, we report the complete genetic sequence of Cutibacterium acnes type strain ATCC6919. Methods: Whole-genome sequencing of Cutibacterium acnes ATCC6919 was performed using both the Illumina Hiseq4000 and PacBio RSII single-molecule real-time sequencing platforms. The generated sequence reads were de novo assembled using the HGAP3 protocol of single-molecule real-time analysis v.2.3.0 software. The draft genome was annotated and further analyzed by various bioinformatics tools. Results: The total genome length of Cutibacterium acnes ATCC6919 was 2,495,001bp (60.02% G + C content), with 2,450 coding sequences including 2,358 proteins, 45 tRNAs, 9 rRNAs, and 1 sRNA. The Comprehensive Antibiotic Resistance Database showed that the gene (thy A) found in ATCC6919 was associated with resistance to aminosalicylic acid. Antimicrobial susceptibility testing showed that this isolate was not sensitive to metronidazole and sulfamethoxazole, but was sensitive to all other tested antimicrobials (erythromycin, azithromycin, clarithromycin, tetracycline, minocycline, trimethoprim, levofloxacin, ceftriaxone, and doxycycline). Conclusion: This study reports the complete genome sequence of Cutibacterium acnes ATCC6919, which provides a valuable reference for comparative analysis based on the genomic characteristics and resistance gene diversity of Cutibacterium acnes.
目的:广泛使用抗生素治疗痤疮是产生耐药性痤疮丙酸杆菌的主要原因。然而,痤疮丙酸杆菌的完整基因序列参考文献尚未见报道。在此,我们报告了痤疮棒状杆菌(Cutibacterium acnes)型菌株 ATCC6919 的完整基因序列。方法使用 Illumina Hiseq4000 和 PacBio RSII 单分子实时测序平台对痤疮杆菌 ATCC6919 进行了全基因组测序。使用单分子实时分析 v.2.3.0 软件的 HGAP3 协议对生成的序列读数进行了从头组装。利用各种生物信息学工具对基因组草案进行注释和进一步分析。结果痤疮杆菌ATCC6919的基因组总长度为2,495,001bp(G+C含量为60.02%),共有2,450个编码序列,包括2,358个蛋白质、45个tRNA、9个rRNA和1个sRNA。抗生素耐药性综合数据库显示,在 ATCC6919 中发现的基因(thy A)与氨基水杨酸耐药性有关。抗菌药敏感性测试显示,该分离株对甲硝唑和磺胺甲噁唑不敏感,但对所有其他测试过的抗菌药(红霉素、阿奇霉素、克拉霉素、四环素、米诺环素、三甲氧苄啶、左氧氟沙星、头孢曲松和强力霉素)都敏感。结论本研究报告了痤疮棒状杆菌 ATCC6919 的完整基因组序列,为根据痤疮棒状杆菌的基因组特征和耐药基因多样性进行比较分析提供了有价值的参考。
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引用次数: 0
Prevention and Treatment of Skin Damage Caused by Personal Protective Equipment: Experience of the First-Line Clinicians Treating 2019-nCoV Infection. 预防和治疗个人防护装备造成的皮肤损伤:治疗 2019-nCoV 感染的一线临床医生的经验。
Pub Date : 2020-03-13 DOI: 10.1097/JD9.0000000000000085
Nuo-Ya Zhou, Liu Yang, Li-Yun Dong, Yan Li, Xiang-Jie An, Jing Yang, Liu Yang, Chang-Zheng Huang, Juan Tao
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引用次数: 0
Consensus on Pre-examination and Triage in Clinic of Dermatology During Outbreak of COVID-19 From Chinese Experts. 中国专家就 COVID-19 爆发期间皮肤科门诊的预检和分诊达成共识。
Pub Date : 2020-03-13 DOI: 10.1097/JD9.0000000000000084
Hui Zhang, Hai Long, Lin Ma, Gang Wang, Qi-Ri Mu, Yu-Ping Ran, Quan-Zhong Liu, Sheng-Xiang Xiao, Xue-Jun Zhang, Jian-Zhong Zhang, Fu-Ren Zhang, Li He, Ai-Jun Chen, Xiang Chen, Jie Zheng, Rong-Ya Yang, Zhi-Rong Yao, Ping Tu, Yu-Zhen Li, Xing-Hua Gao, Jin-Hua Xu, Heng Gu, Bo Cheng, Wei Lai, Qian-Jin Lu

The 2019 novel coronavirus infection has brought a great challenge in prevention and control of the national epidemic of coronavirus disease 2019 (COVID-19) in China. During the fight against the epidemic of COVID-19, properly carrying out pre-examination and triage for patients with skin lesions and fever has been a practical problem encountered in hospitals for skin diseases as well as clinics of dermatology in general hospitals. Considering that certain skin diseases may have symptom of fever, and some of the carriers of 2019 novel coronavirus and patients with COVID-19 at their early stage may do not present any symptoms of COVID-19, to properly deal with the visitors to clinics of dermatology, the Chinese Society of Dermatology organized experts to formulate the principles and procedures for pre-examination and triage of visitors to clinics of dermatology during the epidemic of COVID-19.

2019年新型冠状病毒感染给我国2019年全国冠状病毒病疫情(COVID-19)防控工作带来了巨大挑战。在抗击COVID-19疫情的过程中,如何做好皮损发热患者的预检分诊一直是皮肤病医院和综合医院皮肤科门诊遇到的实际问题。考虑到某些皮肤病可能有发热症状,而部分2019年新型冠状病毒携带者和COVID-19患者早期可能没有任何COVID-19症状,为妥善处理皮肤科门诊就诊人员,中华医学会皮肤性病学分会组织专家制定了COVID-19流行期间皮肤科门诊就诊人员预检分诊原则和流程。
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引用次数: 0
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International journal of dermatology and venereology
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