首页 > 最新文献

iRadiology最新文献

英文 中文
Physician Attitudes About Ultrasound-Guided Procedures 医生对超声引导手术的态度
Pub Date : 2025-01-09 DOI: 10.1002/ird3.114
Emma Barry, Sanyukta Deshmukh, Vivian Zhang, Antoan Koshar, Haider Butt, Kenneth Rowe, Siamak Moayedi

Background

We aimed to study physician attitudes toward ultrasound-guided procedures and possible improvements. We hypothesized that the usage of ultrasound in procedures may be limited by a high barrier of entry and that most physicians would choose to adopt software that provides real-time image guidance if accessible.

Methods

A voluntary, cross-sectional survey of physicians at a single site was conducted using a five-point Likert scale. Data analysis included both descriptive and inferential statistical analyses and stratified by categorical descriptors, including variables of formal training, years of experience, and specialty of practice.

Results

One hundred sixteen physicians responded to the survey. The majority disagreed that there was a steep learning curve (57.5%) and that they need more time to identify structures under ultrasound (85.0%). Overall attitudes were mixed about the use of additional software to improve ease of use, but most (55.4%) had positive opinions toward the addition of real-time 3D reconstruction. Respondents without formal training were significantly more likely to agree that additional software would improve ease of ultrasound-guided procedures (p = 0.0389). Radiologists were significantly more likely to perceive a steeper learning curve and less likely to advocate for supplemental software compared to emergency medicine physicians, surgeons, or anesthesiologists.

Conclusions

Surveyed physicians demonstrated comfort with ultrasound-guided procedures and a mixed stance toward the use of additional software to assist with procedures. Those without formal training had significantly more positive attitudes toward the use of additional technology to augment ultrasound-guided procedures, suggesting a knowledge gap that may benefit from such technology.

本研究的目的是研究医生对超声引导手术的态度和可能的改进。我们假设超声在手术中的使用可能会受到高进入门槛的限制,并且大多数医生会选择采用能够提供实时图像引导的软件。方法采用李克特五分制对单个地点的医生进行自愿的横断面调查。数据分析包括描述性和推断性统计分析,并通过分类描述符分层,包括正规培训、经验年数和实践专业等变量。结果116名医生参与了调查。大多数不同意有一个陡峭的学习曲线(57.5%),他们需要更多的时间来识别超声下的结构(85.0%)。对于使用额外的软件来提高易用性,总体态度不一,但大多数(55.4%)对添加实时3D重建持积极态度。没有接受过正式培训的受访者更有可能同意额外的软件会提高超声引导手术的便利性(p = 0.0389)。与急诊内科医生、外科医生或麻醉师相比,放射科医生明显更有可能感知到更陡峭的学习曲线,而且不太可能主张使用补充软件。结论:接受调查的医生对超声引导的手术表示满意,对使用额外的软件来辅助手术的态度不一。那些没有接受过正式培训的人对使用额外的技术来增强超声引导的程序有更积极的态度,这表明知识差距可能受益于这种技术。
{"title":"Physician Attitudes About Ultrasound-Guided Procedures","authors":"Emma Barry,&nbsp;Sanyukta Deshmukh,&nbsp;Vivian Zhang,&nbsp;Antoan Koshar,&nbsp;Haider Butt,&nbsp;Kenneth Rowe,&nbsp;Siamak Moayedi","doi":"10.1002/ird3.114","DOIUrl":"https://doi.org/10.1002/ird3.114","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>We aimed to study physician attitudes toward ultrasound-guided procedures and possible improvements. We hypothesized that the usage of ultrasound in procedures may be limited by a high barrier of entry and that most physicians would choose to adopt software that provides real-time image guidance if accessible.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A voluntary, cross-sectional survey of physicians at a single site was conducted using a five-point Likert scale. Data analysis included both descriptive and inferential statistical analyses and stratified by categorical descriptors, including variables of formal training, years of experience, and specialty of practice.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>One hundred sixteen physicians responded to the survey. The majority disagreed that there was a steep learning curve (57.5%) and that they need more time to identify structures under ultrasound (85.0%). Overall attitudes were mixed about the use of additional software to improve ease of use, but most (55.4%) had positive opinions toward the addition of real-time 3D reconstruction. Respondents without formal training were significantly more likely to agree that additional software would improve ease of ultrasound-guided procedures (<i>p</i> = 0.0389). Radiologists were significantly more likely to perceive a steeper learning curve and less likely to advocate for supplemental software compared to emergency medicine physicians, surgeons, or anesthesiologists.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Surveyed physicians demonstrated comfort with ultrasound-guided procedures and a mixed stance toward the use of additional software to assist with procedures. Those without formal training had significantly more positive attitudes toward the use of additional technology to augment ultrasound-guided procedures, suggesting a knowledge gap that may benefit from such technology.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73508,"journal":{"name":"iRadiology","volume":"3 1","pages":"72-78"},"PeriodicalIF":0.0,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ird3.114","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Natural Language Processing for Chest X-Ray Reports in the Transformer Era: BERT-Like Encoders for Comprehension and GPT-Like Decoders for Generation 变压器时代胸部x光报告的自然语言处理:用于理解的BERT-Like编码器和用于生成的GPT-Like解码器
Pub Date : 2025-01-06 DOI: 10.1002/ird3.115
Han Yuan

We conducted a comprehensive literature search in PubMed to illustrate the current landscape of transformer-based tools from the perspective of transformer's two integral components: encoder exemplified by BERT and decoder characterized by GPT. Also, we discussed adoption barriers and potential solutions in terms of computational burdens, interpretability concerns, ethical issues, hallucination problems, malpractice, and legal liabilities. We hope that this commentary will serve as a foundational introduction for radiologists seeking to explore the evolving technical landscape of chest X-ray report analysis in the transformer era.

我们在PubMed中进行了全面的文献检索,从变压器的两个组成部分:以BERT为例的编码器和以GPT为特征的解码器的角度来说明基于变压器的工具的现状。此外,我们还从计算负担、可解释性问题、伦理问题、幻觉问题、医疗事故和法律责任等方面讨论了采用障碍和潜在解决方案。我们希望这篇评论将作为一个基础介绍,为放射科医生寻求探索在变压器时代不断发展的胸部x光报告分析技术景观。
{"title":"Natural Language Processing for Chest X-Ray Reports in the Transformer Era: BERT-Like Encoders for Comprehension and GPT-Like Decoders for Generation","authors":"Han Yuan","doi":"10.1002/ird3.115","DOIUrl":"https://doi.org/10.1002/ird3.115","url":null,"abstract":"<p>We conducted a comprehensive literature search in PubMed to illustrate the current landscape of transformer-based tools from the perspective of transformer's two integral components: encoder exemplified by BERT and decoder characterized by GPT. Also, we discussed adoption barriers and potential solutions in terms of computational burdens, interpretability concerns, ethical issues, hallucination problems, malpractice, and legal liabilities. We hope that this commentary will serve as a foundational introduction for radiologists seeking to explore the evolving technical landscape of chest X-ray report analysis in the transformer era.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":73508,"journal":{"name":"iRadiology","volume":"3 4","pages":"295-301"},"PeriodicalIF":0.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ird3.115","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144909910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic Review of Phase Aberration Correction Algorithms for Transcranial Focused Ultrasound 经颅聚焦超声相位像差校正算法的系统综述
Pub Date : 2024-12-19 DOI: 10.1002/ird3.112
Mingyu Wang, Zhouyang Xu, Bingbing Cheng

Transcranial focused ultrasound (tFUS) is an emerging modality with strong potential for non-invasively treating brain disorders. However, the inhomogeneity and complex structure of the skull induce substantial phase aberrations and pressure attenuation; these can distort and shift the acoustic focus, thus hindering the efficiency of tFUS therapy. To achieve effective treatments, phased array transducers combined with aberration correction algorithms are commonly implemented. The present report aims to provide a comprehensive review of the current methods used for tFUS phase aberration correction. We first searched the PubMed and Web of Science databases for studies on phase aberration correction algorithms, identifying 54 articles for review. Relevant information, including the principles of algorithms and refocusing performances, were then extracted from the selected articles. The phase correction algorithms involved two main steps: acoustic field estimation and transmitted pulse adjustment. Our review identified key benchmarks for evaluating the effectiveness of these algorithms, each of which was used in at least three studies. These benchmarks included pressure and intensity, positioning error, focal region size, peak sidelobe ratio, and computational efficiency. Algorithm performances varied under different benchmarks, thus highlighting the importance of application-specific algorithm selection for achieving optimal tFUS therapy outcomes. The present review provides a thorough overview and comparison of various phase correction algorithms, and may offer valuable guidance to tFUS researchers when selecting appropriate phase correction algorithms for specific applications.

经颅聚焦超声(tFUS)是一种新兴的无创治疗脑部疾病的方法。然而,颅骨的非均匀性和复杂结构导致了大量的相位像差和压力衰减;这些会扭曲和转移声学焦点,从而阻碍了tFUS治疗的效率。为了实现有效的治疗,相控阵换能器与像差校正算法相结合。本报告的目的是提供一个全面的审查目前的方法用于tFUS相位像差校正。我们首先检索了PubMed和Web of Science数据库中有关相位像差校正算法的研究,确定了54篇文章进行综述。然后从选定的文章中提取相关信息,包括算法原理和重新聚焦性能。相位校正算法包括两个主要步骤:声场估计和发射脉冲调整。我们的综述确定了评估这些算法有效性的关键基准,其中每一个至少在三个研究中使用。这些基准包括压力和强度、定位误差、焦点区域大小、峰值旁瓣比和计算效率。算法性能在不同的基准下有所不同,因此突出了针对特定应用的算法选择对于实现最佳tFUS治疗结果的重要性。本文对各种相位校正算法进行了全面的综述和比较,可以为tFUS研究人员在具体应用中选择合适的相位校正算法提供有价值的指导。
{"title":"Systematic Review of Phase Aberration Correction Algorithms for Transcranial Focused Ultrasound","authors":"Mingyu Wang,&nbsp;Zhouyang Xu,&nbsp;Bingbing Cheng","doi":"10.1002/ird3.112","DOIUrl":"https://doi.org/10.1002/ird3.112","url":null,"abstract":"<p>Transcranial focused ultrasound (tFUS) is an emerging modality with strong potential for non-invasively treating brain disorders. However, the inhomogeneity and complex structure of the skull induce substantial phase aberrations and pressure attenuation; these can distort and shift the acoustic focus, thus hindering the efficiency of tFUS therapy. To achieve effective treatments, phased array transducers combined with aberration correction algorithms are commonly implemented. The present report aims to provide a comprehensive review of the current methods used for tFUS phase aberration correction. We first searched the PubMed and Web of Science databases for studies on phase aberration correction algorithms, identifying 54 articles for review. Relevant information, including the principles of algorithms and refocusing performances, were then extracted from the selected articles. The phase correction algorithms involved two main steps: acoustic field estimation and transmitted pulse adjustment. Our review identified key benchmarks for evaluating the effectiveness of these algorithms, each of which was used in at least three studies. These benchmarks included pressure and intensity, positioning error, focal region size, peak sidelobe ratio, and computational efficiency. Algorithm performances varied under different benchmarks, thus highlighting the importance of application-specific algorithm selection for achieving optimal tFUS therapy outcomes. The present review provides a thorough overview and comparison of various phase correction algorithms, and may offer valuable guidance to tFUS researchers when selecting appropriate phase correction algorithms for specific applications.</p>","PeriodicalId":73508,"journal":{"name":"iRadiology","volume":"3 1","pages":"26-46"},"PeriodicalIF":0.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ird3.112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anatomic Boundary-Aware Explanation for Convolutional Neural Networks in Diagnostic Radiology 卷积神经网络在诊断放射学中的解剖边界感知解释
Pub Date : 2024-12-18 DOI: 10.1002/ird3.113
Han Yuan

Background

Convolutional neural networks (CNN) have achieved remarkable success in medical image analysis. However, unlike some general-domain tasks where model accuracy is paramount, medical applications demand both accuracy and explainability due to the high stakes affecting patients' lives. Based on model explanations, clinicians can evaluate the diagnostic decisions suggested by CNN. Nevertheless, prior explainable artificial intelligence methods treat medical image tasks akin to general vision tasks, following end-to-end paradigms to generate explanations and frequently overlooking crucial clinical domain knowledge.

Methods

We propose a plug-and-play module that explicitly integrates anatomic boundary information into the explanation process for CNN-based thoracopathy classifiers. To generate the anatomic boundary of the lung parenchyma, we utilize a lung segmentation model developed on external public datasets and deploy it on the unseen target dataset to constrain model explanations within the lung parenchyma for the clinical task of thoracopathy classification.

Results

Assessed by the intersection over union and dice similarity coefficient between model-extracted explanations and expert-annotated lesion areas, our method consistently outperformed the baseline devoid of clinical domain knowledge in 71 out of 72 scenarios, encompassing 3 CNN architectures (VGG-11, ResNet-18, and AlexNet), 2 classification settings (binary and multi-label), 3 explanation methods (Saliency Map, Grad-CAM, and Integrated Gradients), and 4 co-occurred thoracic diseases (Atelectasis, Fracture, Mass, and Pneumothorax).

Conclusions

We underscore the effectiveness of leveraging radiology knowledge in improving model explanations for CNN and envisage that it could inspire future efforts to integrate clinical domain knowledge into medical image analysis.

背景卷积神经网络(CNN)在医学图像分析领域取得了巨大成功。然而,与一些模型准确性至关重要的一般领域任务不同,医疗应用对准确性和可解释性都有很高的要求,因为这关系到病人的生命。根据模型的解释,临床医生可以评估 CNN 提出的诊断建议。然而,先前的可解释人工智能方法在处理医学图像任务时与处理一般视觉任务类似,都是按照端到端范式生成解释,往往忽略了关键的临床领域知识。 方法 我们提出了一种即插即用模块,可将解剖学边界信息明确整合到基于 CNN 的胸廓病分类器的解释过程中。为了生成肺实质的解剖学边界,我们利用在外部公共数据集上开发的肺分割模型,并将其部署在未见的目标数据集上,以限制模型在肺实质内的解释,从而完成胸廓病分类的临床任务。 结果 通过模型提取的解释与专家标注的病变区域之间的交集大于联合和骰子相似系数进行评估,我们的方法在 72 个场景中的 71 个场景中始终优于没有临床领域知识的基线方法、其中包括 3 种 CNN 架构(VGG-11、ResNet-18 和 AlexNet)、2 种分类设置(二元和多标签)、3 种解释方法(Saliency Map、Grad-CAM 和 Integrated Gradients)以及 4 种同时出现的胸部疾病(胸腔积液、骨折、肿块和气胸)。 结论 我们强调了利用放射学知识改进 CNN 模型解释的有效性,并设想这将激励未来将临床领域知识整合到医学图像分析中的努力。
{"title":"Anatomic Boundary-Aware Explanation for Convolutional Neural Networks in Diagnostic Radiology","authors":"Han Yuan","doi":"10.1002/ird3.113","DOIUrl":"https://doi.org/10.1002/ird3.113","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Convolutional neural networks (CNN) have achieved remarkable success in medical image analysis. However, unlike some general-domain tasks where model accuracy is paramount, medical applications demand both accuracy and explainability due to the high stakes affecting patients' lives. Based on model explanations, clinicians can evaluate the diagnostic decisions suggested by CNN. Nevertheless, prior explainable artificial intelligence methods treat medical image tasks akin to general vision tasks, following end-to-end paradigms to generate explanations and frequently overlooking crucial clinical domain knowledge.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We propose a plug-and-play module that explicitly integrates anatomic boundary information into the explanation process for CNN-based thoracopathy classifiers. To generate the anatomic boundary of the lung parenchyma, we utilize a lung segmentation model developed on external public datasets and deploy it on the unseen target dataset to constrain model explanations within the lung parenchyma for the clinical task of thoracopathy classification.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Assessed by the intersection over union and dice similarity coefficient between model-extracted explanations and expert-annotated lesion areas, our method consistently outperformed the baseline devoid of clinical domain knowledge in 71 out of 72 scenarios, encompassing 3 CNN architectures (VGG-11, ResNet-18, and AlexNet), 2 classification settings (binary and multi-label), 3 explanation methods (Saliency Map, Grad-CAM, and Integrated Gradients), and 4 co-occurred thoracic diseases (Atelectasis, Fracture, Mass, and Pneumothorax).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>We underscore the effectiveness of leveraging radiology knowledge in improving model explanations for CNN and envisage that it could inspire future efforts to integrate clinical domain knowledge into medical image analysis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73508,"journal":{"name":"iRadiology","volume":"3 1","pages":"47-60"},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ird3.113","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence in medical imaging 医学成像中的人工智能
Pub Date : 2024-12-15 DOI: 10.1002/ird3.111
Bin Huang, Bo Gao

With the rapid development of science and technology, the application of artificial intelligence (AI) in various fields is constantly expanding, especially in the field of medical imaging [1]. AI technology is suitable to be applied to standardized digital medical image big data based on digital imaging and communications in medicine protocol and picture archiving and communication system. With the integration of AI technology, this field is undergoing profound transformation, not only improving the accuracy and efficiency of diagnosis, but also significantly reducing the workload of doctors [2]. At present, AI is widely used in medical imaging, including risk modeling and stratification, personalized screening, diagnosis (including classification of molecular pathologic subtypes), treatment response prediction, prognosis prediction, image segmentation, and image quality control. AI can help doctors identify and analyze lesions in various medical images, especially in diseases such as lung, breast, and prostate cancer. The research mainly focuses on the identification of benign and malignant, the measurement of risk factors, prognosis judgment and treatment guidance, and it is increasingly being used in the field of psychoradiology [3]. In addition, AI is also focused on reducing image acquisition time and improving data quality. Through deep learning algorithms, AI can optimize imaging parameters, improve imaging quality, and reduce noise and artifacts.

This special issue of AI includes seven latest studies, which covers artificial intelligence of disease diagnosis and prediction, imaging technology model construction, image segmentation and quality control. Wang et al. [4] used systematic review to summarize the technical methods, clinical applications and existing problems of artificial intelligence in cerebrovascular diseases, they found that the availability of algorithms, reliability of validation, and consistency of evaluation metrics may facilitate better clinical applicability and acceptance. Zhu et al. [5] proposed a diffusion magnetic diffusion magnetic (dMRI) index reconstruction model based on deep learning methods-qIRR-Net and a training framework based on data enhancement and consistency loss, The reconstruction of dMRI index is realized without the influence of signal inhomogeneity, and the model validity is verified on simulated inhomogeneity data and real ultra-high field data, thus promoting the application of ultra-high field dMRI technology in medicine and clinic. Artificial intelligence-assisted compressed sensing is a deep learning technology based on convolutional neural networks which can reconstruct images with ultra-high resolution and reduce noise. On the premise of ensuring the quality of the image, the collection time of the sequence is greatly shortened. In this special issue, The application of assisted compressed sensing technology in 5T MRI

随着科学技术的飞速发展,人工智能(AI)在各个领域的应用不断扩大,尤其是在医学影像领域。AI技术适合应用于医学协议和图像存档通信系统中基于数字成像和通信的标准化数字医学图像大数据。随着人工智能技术的融合,这一领域正在发生深刻的变革,不仅提高了诊断的准确性和效率,而且大大减少了医生的工作量。目前,AI广泛应用于医学影像学,包括风险建模与分层、个性化筛查、诊断(包括分子病理亚型分类)、治疗反应预测、预后预测、图像分割、图像质量控制等。人工智能可以帮助医生识别和分析各种医学图像中的病变,特别是在肺癌、乳腺癌和前列腺癌等疾病中。研究主要集中在良恶性的鉴别、危险因素的测量、预后判断和治疗指导等方面,在精神放射学领域的应用越来越广泛。此外,人工智能还专注于减少图像采集时间和提高数据质量。通过深度学习算法,人工智能可以优化成像参数,提高成像质量,减少噪声和伪影。本期《人工智能》特刊收录了七项最新研究成果,涵盖了疾病诊断与预测、成像技术模型构建、图像分割与质量控制等方面的人工智能。Wang等人[4]采用系统综述的方法对人工智能在脑血管疾病中的技术方法、临床应用及存在的问题进行了总结,发现算法的可用性、验证的可靠性、评价指标的一致性可能有利于更好的临床适用性和可接受性。Zhu等人[5]提出了一种基于深度学习方法- qir - net的弥散磁(diffusion magnetic diffusion magnetic, dMRI)指标重建模型和一种基于数据增强和一致性损失的训练框架,在不受信号非均匀性影响的情况下实现了dMRI指标的重建,并在模拟非均匀性数据和真实超高场数据上验证了模型的有效性,从而促进了超高场dMRI技术在医学和临床中的应用。人工智能辅助压缩感知是一种基于卷积神经网络的深度学习技术,可以实现超高分辨率图像重构和降噪。在保证图像质量的前提下,大大缩短了序列的采集时间。在本期特刊中,Zhou等人[6]将辅助压缩感知技术应用于5T MRI,显著缩短了MRI扫描时间,保证了图像质量和诊断准确性。本创新研究可有效提高临床工作效率。AI技术可以在放射组学中发挥重要作用,通过深度学习模型,自动提取大量定量图像特征,并结合患者临床数据、基因表达信息,构建高精度的诊断和预测模型[7]。Pawan等[bbb]从放射组学、机器学习和深度学习等方面综述了前列腺癌骨转移的研究。他们提出了多种策略,包括分类/预测、检测、分割和评估前列腺骨转移的放射学方法;为相关研究提供了系统的学习机会。人工智能在医学影像领域的应用显示出巨大的潜力和优势。从智能成像系统的优化到复杂图像的处理和分析,人工智能技术正在将医学成像推向新的高度。未来,人工智能技术将进一步推动个性化医疗、远程诊断、跨学科融合的发展。黄斌:撰稿-原稿(等)高波:写作——审稿和编辑(主笔)。高波教授是《放射学》编委会成员。为了尽量减少偏倚,他被排除在所有与接受这篇文章发表相关的编辑决策之外。其余的作者声明没有利益冲突。 国家自然科学基金项目,资助/奖励号:81871333,82260340;​贵州省教委2020年创新群体项目,资助/奖励号:KY[2021]017;贵州省科学与工程学院;科技项目批准/奖励号:ZK[2024]通则194;贵州省科学与工程学院;科技项目,批准/奖励号:[2020]4Y159,[2021]430。不适用。不适用。
{"title":"Artificial intelligence in medical imaging","authors":"Bin Huang,&nbsp;Bo Gao","doi":"10.1002/ird3.111","DOIUrl":"https://doi.org/10.1002/ird3.111","url":null,"abstract":"<p>With the rapid development of science and technology, the application of artificial intelligence (AI) in various fields is constantly expanding, especially in the field of medical imaging [<span>1</span>]. AI technology is suitable to be applied to standardized digital medical image big data based on digital imaging and communications in medicine protocol and picture archiving and communication system. With the integration of AI technology, this field is undergoing profound transformation, not only improving the accuracy and efficiency of diagnosis, but also significantly reducing the workload of doctors [<span>2</span>]. At present, AI is widely used in medical imaging, including risk modeling and stratification, personalized screening, diagnosis (including classification of molecular pathologic subtypes), treatment response prediction, prognosis prediction, image segmentation, and image quality control. AI can help doctors identify and analyze lesions in various medical images, especially in diseases such as lung, breast, and prostate cancer. The research mainly focuses on the identification of benign and malignant, the measurement of risk factors, prognosis judgment and treatment guidance, and it is increasingly being used in the field of psychoradiology [<span>3</span>]. In addition, AI is also focused on reducing image acquisition time and improving data quality. Through deep learning algorithms, AI can optimize imaging parameters, improve imaging quality, and reduce noise and artifacts.</p><p>This special issue of AI includes seven latest studies, which covers artificial intelligence of disease diagnosis and prediction, imaging technology model construction, image segmentation and quality control. Wang et al. [<span>4</span>] used systematic review to summarize the technical methods, clinical applications and existing problems of artificial intelligence in cerebrovascular diseases, they found that the availability of algorithms, reliability of validation, and consistency of evaluation metrics may facilitate better clinical applicability and acceptance. Zhu et al. [<span>5</span>] proposed a diffusion magnetic diffusion magnetic (dMRI) index reconstruction model based on deep learning methods-qIRR-Net and a training framework based on data enhancement and consistency loss, The reconstruction of dMRI index is realized without the influence of signal inhomogeneity, and the model validity is verified on simulated inhomogeneity data and real ultra-high field data, thus promoting the application of ultra-high field dMRI technology in medicine and clinic. Artificial intelligence-assisted compressed sensing is a deep learning technology based on convolutional neural networks which can reconstruct images with ultra-high resolution and reduce noise. On the premise of ensuring the quality of the image, the collection time of the sequence is greatly shortened. In this special issue, The application of assisted compressed sensing technology in 5T MRI","PeriodicalId":73508,"journal":{"name":"iRadiology","volume":"2 6","pages":"525-526"},"PeriodicalIF":0.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ird3.111","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143252565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exposing the Rad to Radionuclide: Why Early Education in Theranostics Is Important to Radiologists 放射性核素:为什么早期治疗学教育对放射科医生很重要
Pub Date : 2024-12-12 DOI: 10.1002/ird3.106
Andy Ho, Nicola Luppino, Lincoln J. Lim

{"title":"Exposing the Rad to Radionuclide: Why Early Education in Theranostics Is Important to Radiologists","authors":"Andy Ho,&nbsp;Nicola Luppino,&nbsp;Lincoln J. Lim","doi":"10.1002/ird3.106","DOIUrl":"https://doi.org/10.1002/ird3.106","url":null,"abstract":"<p>\u0000 \u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":73508,"journal":{"name":"iRadiology","volume":"3 1","pages":"79-85"},"PeriodicalIF":0.0,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ird3.106","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An investigation into the applicability of rapid artificial intelligence-assisted compressed sensing in brain magnetic resonance imaging performed at 5 Tesla field strength 5特斯拉场强下快速人工智能辅助压缩感知在脑磁共振成像中的适用性研究
Pub Date : 2024-12-08 DOI: 10.1002/ird3.108
Liqiang Zhou, Jiaqi Wang

Background

Brain magnetic resonance imaging (MRI) at 5 T offers unprecedented spatial resolution but is often limited by long scan times. Acceleration techniques, such as compressed sensing (CS) and artificial intelligence-assisted compressed sensing (ACS), have the potential to speed up the acquisition process while maintaining image quality. This study aims to evaluate and compare the performance of CS and ACS (with various acceleration factors) in brain MRI imaging at 5 T.

Methods

In this study, we enrolled 12 healthy volunteers and compared ACS-accelerated 5 T brain MRI with conventional methods of CS. The ACS acceleration factors for the brain protocol, consisting of 3D T1-weighted sequences and 2D T2-weighted sequences, were optimized in a pilot study on healthy volunteers (acceleration factor, 2.06–3.41× in T2-weighted imaging and 3.52–8.49× in T1-weighted imaging). We evaluated the images acquired from patients using various acceleration methods on the basis of acquisition times, the signal-to-noise ratio (SNR), the contrast-to-noise ratio, subjective image quality, and diagnostic agreement.

Results

Our findings revealed that ACS acceleration significantly reduced the acquisition times for T1- and T2-weighted sequences by up to 43% and 53%, respectively, compared with traditional CS at 5 T. Importantly, this acceleration was achieved while maintaining excellent image quality, demonstrated by higher or comparable SNR and contrast-to-noise ratio values.

Conclusions

The optimal ACS acceleration factors for 5 T brain MRI were determined to be 2.73× for 2D T2-weighted sequences and 6.5× for 3D T1-weighted sequences. ACS not only facilitates rapid imaging but also ensures comparable image quality and diagnostic performance, highlighting its potential to revolutionize high-field MRI scanning.

5 T的脑磁共振成像(MRI)提供了前所未有的空间分辨率,但往往受到长扫描时间的限制。加速技术,如压缩感知(CS)和人工智能辅助压缩感知(ACS),有可能在保持图像质量的同时加快采集过程。本研究旨在评价和比较CS和ACS(不同加速因子)在5 T脑MRI成像中的表现。方法在本研究中,我们招募了12名健康志愿者,将ACS加速5 T脑MRI与常规CS方法进行比较。在健康志愿者的前期研究中,优化了由3D t1加权序列和2D t2加权序列组成的脑协议ACS加速因子(加速因子为t2加权成像2.06 ~ 3.41×, t1加权成像3.52 ~ 8.49×)。我们根据采集次数、信噪比(SNR)、对比噪声比、主观图像质量和诊断一致性对使用各种加速方法从患者身上获取的图像进行评估。我们的研究结果表明,与传统的5 t CS相比,ACS加速显著减少了T1和t2加权序列的采集时间,分别减少了43%和53%。重要的是,这种加速是在保持优异图像质量的同时实现的,这可以通过更高或相当的信噪比和噪比值来证明。结论5t脑MRI最佳ACS加速因子2D t2加权序列为2.73×, 3D t1加权序列为6.5×。ACS不仅促进了快速成像,而且确保了相当的图像质量和诊断性能,突出了其革命性的高场MRI扫描的潜力。
{"title":"An investigation into the applicability of rapid artificial intelligence-assisted compressed sensing in brain magnetic resonance imaging performed at 5 Tesla field strength","authors":"Liqiang Zhou,&nbsp;Jiaqi Wang","doi":"10.1002/ird3.108","DOIUrl":"https://doi.org/10.1002/ird3.108","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Brain magnetic resonance imaging (MRI) at 5 T offers unprecedented spatial resolution but is often limited by long scan times. Acceleration techniques, such as compressed sensing (CS) and artificial intelligence-assisted compressed sensing (ACS), have the potential to speed up the acquisition process while maintaining image quality. This study aims to evaluate and compare the performance of CS and ACS (with various acceleration factors) in brain MRI imaging at 5 T.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this study, we enrolled 12 healthy volunteers and compared ACS-accelerated 5 T brain MRI with conventional methods of CS. The ACS acceleration factors for the brain protocol, consisting of 3D T1-weighted sequences and 2D T2-weighted sequences, were optimized in a pilot study on healthy volunteers (acceleration factor, 2.06–3.41× in T2-weighted imaging and 3.52–8.49× in T1-weighted imaging). We evaluated the images acquired from patients using various acceleration methods on the basis of acquisition times, the signal-to-noise ratio (SNR), the contrast-to-noise ratio, subjective image quality, and diagnostic agreement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Our findings revealed that ACS acceleration significantly reduced the acquisition times for T1- and T2-weighted sequences by up to 43% and 53%, respectively, compared with traditional CS at 5 T. Importantly, this acceleration was achieved while maintaining excellent image quality, demonstrated by higher or comparable SNR and contrast-to-noise ratio values.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The optimal ACS acceleration factors for 5 T brain MRI were determined to be 2.73× for 2D T2-weighted sequences and 6.5× for 3D T1-weighted sequences. ACS not only facilitates rapid imaging but also ensures comparable image quality and diagnostic performance, highlighting its potential to revolutionize high-field MRI scanning.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73508,"journal":{"name":"iRadiology","volume":"2 6","pages":"584-593"},"PeriodicalIF":0.0,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ird3.108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143248945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rete Middle Cerebral Artery 大脑中动脉
Pub Date : 2024-12-05 DOI: 10.1002/ird3.109
Yongming Wang, Xi Chen, Junsheng Liu

A 53 year-old woman presented with a 4 year history of recurrent dizziness episodes. Each episode lasted approximately 1 week and was not accompanied by nausea, or vomiting. Comprehensive vestibular assessments, including vestibular function tests, Dix–Hallpike maneuver, and the roll test, were all negative. The patient reported no atherosclerotic risk factors, such as hypertension, hyperlipidemia or diabetes mellitus, and her family history was unremarkable. General physical and neurological examinations were unremarkable. Central causes of dizziness were considered. A computed tomography angiography of the head revealed a plexiform configuration in the M1 segment of the right middle cerebral artery (MCA), with no other significant abnormalities (Figure 1a). Moyamoya disease was considered a possible diagnosis. Subsequent digital subtraction angiography demonstrated the absence of a normal right M1 segment, with a twig-like vascular network connecting to the distal MCA (Figure 1b,c). Additionally, the right carotid canal was found to be smaller than the left, suggesting potential congenital variants consistent with rete MCA (Figure 1d). The patient was treated with betahistine 6 mg three times daily, resulting in alleviation of her dizziness.

Rete MCA, also known as twig-like MCA, is a rare vascular anomaly characterized by the presence of a twig-like arterial network in the M1 segment of the MCA. This variant may present with either hemorrhagic or ischemic strokes, or, as in this case, with no clinical symptoms. The primary differential diagnoses for rete MCA include moyamoya disease/syndrome and atherosclerotic occlusion. In contrast to these conditions, rete MCA is typically unilateral, occurs exclusively in the M1 segment with a distinctive twig-like appearance, and does not involve atherosclerotic risk factors. Notably, it preserves the caliber and flow of the distal MCA. In surgical settings, rete MCA often presents as a white cord-like structure. Accurate diagnosis is essential, particularly for asymptomatic patients, to avoid unnecessary concerns about occlusion. For symptomatic individuals, surgical intervention may be considered.

Yongming Wang: writing–original draft (lead). Xi Chen: writing–original draft (equal). Junsheng Liu: writing–review and editing (equal).

This study was approved by the Ethics Committee of The People's Hospital of Pingchang in 2024 (Approval Number: 20240731-121).

The patient provided informed consent for the publication of the case.

The authors declare no conflicts of interest.

一名53岁女性,有4年复发性头晕发作史。每次发作持续约1周,未伴有恶心或呕吐。包括前庭功能测试、Dix-Hallpike机动和滚动试验在内的综合前庭评估均为阴性。患者报告无动脉粥样硬化危险因素,如高血压、高脂血症或糖尿病,家族史无显著差异。一般的身体和神经检查无明显异常。考虑头晕的主要原因。头部ct血管造影显示右侧大脑中动脉(MCA) M1段呈丛状结构,未见其他明显异常(图1a)。烟雾病被认为是可能的诊断。随后的数字减影血管造影显示没有正常的右侧M1段,有一个细枝状的血管网络连接到MCA远端(图1b,c)。此外,右颈动脉管小于左颈动脉管,提示潜在的先天性变异与网状MCA一致(图1d)。患者给予倍他司汀6 mg,每日3次,头晕症状减轻。Rete MCA,也被称为小枝样MCA,是一种罕见的血管异常,其特征是在MCA的M1段存在小枝样动脉网络。这种变异可能表现为出血性或缺血性中风,或者像本病例一样,没有临床症状。视网膜MCA的主要鉴别诊断包括烟雾病/综合征和动脉粥样硬化闭塞。与这些情况相反,网状MCA通常是单侧的,仅发生在M1段,具有独特的细枝样外观,不涉及动脉粥样硬化的危险因素。值得注意的是,它保留了中动脉远端的口径和流量。在外科手术中,中动脉网常表现为白色索状结构。准确的诊断是至关重要的,特别是对无症状的患者,以避免不必要的担心闭塞。对于有症状的个体,可以考虑手术干预。王永明:写作——原稿(主笔)。陈曦:写作-原稿(相等)。刘俊生:写作-审编(平等)。本研究于2024年获得平昌市人民医院伦理委员会批准(批准号:20240731-121)。患者对病例的发表表示知情同意。作者声明无利益冲突。
{"title":"Rete Middle Cerebral Artery","authors":"Yongming Wang,&nbsp;Xi Chen,&nbsp;Junsheng Liu","doi":"10.1002/ird3.109","DOIUrl":"https://doi.org/10.1002/ird3.109","url":null,"abstract":"<p>A 53 year-old woman presented with a 4 year history of recurrent dizziness episodes. Each episode lasted approximately 1 week and was not accompanied by nausea, or vomiting. Comprehensive vestibular assessments, including vestibular function tests, Dix–Hallpike maneuver, and the roll test, were all negative. The patient reported no atherosclerotic risk factors, such as hypertension, hyperlipidemia or diabetes mellitus, and her family history was unremarkable. General physical and neurological examinations were unremarkable. Central causes of dizziness were considered. A computed tomography angiography of the head revealed a plexiform configuration in the M1 segment of the right middle cerebral artery (MCA), with no other significant abnormalities (Figure 1a). Moyamoya disease was considered a possible diagnosis. Subsequent digital subtraction angiography demonstrated the absence of a normal right M1 segment, with a twig-like vascular network connecting to the distal MCA (Figure 1b,c). Additionally, the right carotid canal was found to be smaller than the left, suggesting potential congenital variants consistent with rete MCA (Figure 1d). The patient was treated with betahistine 6 mg three times daily, resulting in alleviation of her dizziness.</p><p>Rete MCA, also known as twig-like MCA, is a rare vascular anomaly characterized by the presence of a twig-like arterial network in the M1 segment of the MCA. This variant may present with either hemorrhagic or ischemic strokes, or, as in this case, with no clinical symptoms. The primary differential diagnoses for rete MCA include moyamoya disease/syndrome and atherosclerotic occlusion. In contrast to these conditions, rete MCA is typically unilateral, occurs exclusively in the M1 segment with a distinctive twig-like appearance, and does not involve atherosclerotic risk factors. Notably, it preserves the caliber and flow of the distal MCA. In surgical settings, rete MCA often presents as a white cord-like structure. Accurate diagnosis is essential, particularly for asymptomatic patients, to avoid unnecessary concerns about occlusion. For symptomatic individuals, surgical intervention may be considered.</p><p><b>Yongming Wang:</b> writing–original draft (lead). <b>Xi Chen:</b> writing–original draft (equal). <b>Junsheng Liu:</b> writing–review and editing (equal).</p><p>This study was approved by the Ethics Committee of The People's Hospital of Pingchang in 2024 (Approval Number: 20240731-121).</p><p>The patient provided informed consent for the publication of the case.</p><p>The authors declare no conflicts of interest.</p>","PeriodicalId":73508,"journal":{"name":"iRadiology","volume":"3 1","pages":"86-87"},"PeriodicalIF":0.0,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ird3.109","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Propofol-Induced Moderate–Deep Sedation Modulates Pediatric Neural Activity: A Functional Connectivity Study 丙泊酚诱导的中度深度镇静可调节小儿神经活动:功能连接性研究
Pub Date : 2024-12-05 DOI: 10.1002/ird3.110
Qiang Zheng, Yiyu Zhang, Lin Zhang, Jian Wang, Jungang Liu

Background

Previous studies have demonstrated the underlying neurophysiologic mechanism during general anesthesia in adults. However, the mechanism of propofol-induced moderate–deep sedation (PMDS) in modulating pediatric neural activity remains unknown, which therefore was investigated in the present study based on functional magnetic resonance imaging (fMRI).

Methods

A total of 41 children (5.10 ± 1.14 years, male/female 21/20) with fMRI were employed to construct the functional connectivity network (FCN). The network communication, graph-theoretic properties, and network hub identification were statistically analyzed (t test and Bonferroni correction) between sedation (21 children) and awake (20 children) groups. All involved analyses were established on the whole-brain FCN and seven sub-networks, which included the default mode network (DMN), dorsal attentional network (DAN), salience network (SAN), auditory network (AUD), visual network (VIS), subcortical network (SUB), and other networks (Other).

Results

Under PMDS, significant decreases in network communication were observed between SUB-VIS, SUB-DAN, and VIS-DAN, and between brain regions from the temporal lobe, limbic system, and subcortical tissues. However, no significant decrease in thalamus-related communication was observed. Most graph-theoretic properties were significantly decreased in the sedation group, and all graphical features of the DMN showed significant group differences. The superior parietal cortex with different neurological functions was identified as a network hub that was not greatly affected.

Conclusions

Although the children had a depressed level of neural activity under PMDS, the crucial thalamus-related communication was maintained, and the network hub superior parietal cortex stayed active, which highlighted clinical practices that the human body under PMDS is still perceptible to external stimuli and can be awakened by sound or touch.

背景以往的研究已经证实了成人全身麻醉时潜在的神经生理机制。然而,异丙酚诱导的中深度镇静(PMDS)调节儿童神经活动的机制尚不清楚,因此本研究基于功能磁共振成像(fMRI)进行了研究。方法41例儿童(5.10±1.14岁,男/女21/20)采用功能磁共振成像(fMRI)构建功能连接网络(FCN)。对镇静组(21例)和清醒组(20例)的网络通信、图论性质和网络枢纽识别进行统计学分析(t检验和Bonferroni校正)。所有相关分析均建立在全脑FCN和7个子网络上,包括默认模式网络(DMN)、背侧注意网络(DAN)、显著性网络(SAN)、听觉网络(AUD)、视觉网络(VIS)、皮质下网络(SUB)和其他网络(other)。结果在PMDS治疗下,视觉区、视觉区和视觉区之间以及颞叶、边缘系统和皮层下组织区域之间的网络通信明显减少。然而,没有观察到丘脑相关通讯的显著减少。镇静组大多数图论性质显著降低,DMN的所有图形特征均有显著组间差异。顶叶上皮层具有不同的神经功能,是受影响不大的网络中枢。结论虽然PMDS下儿童的神经活动水平下降,但与丘脑相关的关键通信得以维持,网络中枢顶叶上皮层保持活跃,这突出了临床实践表明PMDS下的人体仍然可以感知外部刺激,并且可以被声音或触摸唤醒。
{"title":"Propofol-Induced Moderate–Deep Sedation Modulates Pediatric Neural Activity: A Functional Connectivity Study","authors":"Qiang Zheng,&nbsp;Yiyu Zhang,&nbsp;Lin Zhang,&nbsp;Jian Wang,&nbsp;Jungang Liu","doi":"10.1002/ird3.110","DOIUrl":"https://doi.org/10.1002/ird3.110","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Previous studies have demonstrated the underlying neurophysiologic mechanism during general anesthesia in adults. However, the mechanism of propofol-induced moderate–deep sedation (PMDS) in modulating pediatric neural activity remains unknown, which therefore was investigated in the present study based on functional magnetic resonance imaging (fMRI).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 41 children (5.10 ± 1.14 years, male/female 21/20) with fMRI were employed to construct the functional connectivity network (FCN). The network communication, graph-theoretic properties, and network hub identification were statistically analyzed (<i>t</i> test and Bonferroni correction) between sedation (21 children) and awake (20 children) groups. All involved analyses were established on the whole-brain FCN and seven sub-networks, which included the default mode network (DMN), dorsal attentional network (DAN), salience network (SAN), auditory network (AUD), visual network (VIS), subcortical network (SUB), and other networks (Other).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Under PMDS, significant decreases in network communication were observed between SUB-VIS, SUB-DAN, and VIS-DAN, and between brain regions from the temporal lobe, limbic system, and subcortical tissues. However, no significant decrease in thalamus-related communication was observed. Most graph-theoretic properties were significantly decreased in the sedation group, and all graphical features of the DMN showed significant group differences. The superior parietal cortex with different neurological functions was identified as a network hub that was not greatly affected.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Although the children had a depressed level of neural activity under PMDS, the crucial thalamus-related communication was maintained, and the network hub superior parietal cortex stayed active, which highlighted clinical practices that the human body under PMDS is still perceptible to external stimuli and can be awakened by sound or touch.</p>\u0000 </section>\u0000 </div>","PeriodicalId":73508,"journal":{"name":"iRadiology","volume":"3 1","pages":"61-71"},"PeriodicalIF":0.0,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ird3.110","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143521970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Foot pain as first presenting symptom of renal cell carcinoma, due to metastatic lesion in medial cuneiform 足部疼痛是肾细胞癌的首要症状,由于内侧楔状体的转移
Pub Date : 2024-12-02 DOI: 10.1002/ird3.107
Christopher Kleimeyer, Stephanie Stoddart, Simon Platt, Craig A. Buchan

Metastatic renal cell carcinoma (RCC) lesions in the foot are a rare entity and uncommon finding in a series of foot radiographs ordered to investigate foot pain. We report the case of a 72 year old male who experienced left foot pain for a year, before developing intermittent haematuria and right flank pain, and subsequently being found to have right RCC with an osseous metastatic lesion in the left medial cuneiform.

转移性肾细胞癌(RCC)病变在足部是一个罕见的实体和罕见的发现,在一系列足部x线片责令调查足部疼痛。我们报告一个72岁男性的病例,在出现间歇性血尿和右侧疼痛之前,他经历了一年的左脚疼痛,随后被发现患有右侧肾细胞癌,并在左侧内侧楔状体发生骨转移。
{"title":"Foot pain as first presenting symptom of renal cell carcinoma, due to metastatic lesion in medial cuneiform","authors":"Christopher Kleimeyer,&nbsp;Stephanie Stoddart,&nbsp;Simon Platt,&nbsp;Craig A. Buchan","doi":"10.1002/ird3.107","DOIUrl":"https://doi.org/10.1002/ird3.107","url":null,"abstract":"<p>Metastatic renal cell carcinoma (RCC) lesions in the foot are a rare entity and uncommon finding in a series of foot radiographs ordered to investigate foot pain. We report the case of a 72 year old male who experienced left foot pain for a year, before developing intermittent haematuria and right flank pain, and subsequently being found to have right RCC with an osseous metastatic lesion in the left medial cuneiform.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":73508,"journal":{"name":"iRadiology","volume":"2 6","pages":"603-608"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ird3.107","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143248145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
iRadiology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1