Ester Lopes de Melo, Bruno Augusto Machado Tavares, Nayara Nílcia Dias Colares, Aline Lopes do Nascimento, H. Carvalho, Andrés Navarrete Castro, Arlindo César Matias Pereira, Carlos Eduardo Winter, I. D. S. Sena, Luiz Fernando Moreira, J. C. T. Carvalho
Aging is a complex process associated with tissue degeneration and an increased risk of age-related diseases. This study aimed to evaluate the impact of Terasen®, a nutraceutical containing standardized extracts of Euterpe oleracea, Myrciaria dubia, and purified oil of Bixa orellana and Astrocaryum aculeatum on the lifespan of Caenorhabditis elegans. The findings demonstrated that Terasen® exhibited significant radical scavenging in vitro, decreased the feeding behavior of C. elegans without affecting the animals’ final size, increased the eggs laid in a concentration-dependent fashion, although the total progeny was reduced compared to the control, and increased the median and maximum lifespan. These findings suggest that Terasen® may improve the lifespan in C. elegans, warranting further investigation.
{"title":"Association of Euterpe oleracea, Bixa orellana, Myciaria dubia, and Astrocaryum aculeatum (the Terasen® Nutraceutical) Increases the Lifespan of Caenorhabditis elegans","authors":"Ester Lopes de Melo, Bruno Augusto Machado Tavares, Nayara Nílcia Dias Colares, Aline Lopes do Nascimento, H. Carvalho, Andrés Navarrete Castro, Arlindo César Matias Pereira, Carlos Eduardo Winter, I. D. S. Sena, Luiz Fernando Moreira, J. C. T. Carvalho","doi":"10.3390/jal3040022","DOIUrl":"https://doi.org/10.3390/jal3040022","url":null,"abstract":"Aging is a complex process associated with tissue degeneration and an increased risk of age-related diseases. This study aimed to evaluate the impact of Terasen®, a nutraceutical containing standardized extracts of Euterpe oleracea, Myrciaria dubia, and purified oil of Bixa orellana and Astrocaryum aculeatum on the lifespan of Caenorhabditis elegans. The findings demonstrated that Terasen® exhibited significant radical scavenging in vitro, decreased the feeding behavior of C. elegans without affecting the animals’ final size, increased the eggs laid in a concentration-dependent fashion, although the total progeny was reduced compared to the control, and increased the median and maximum lifespan. These findings suggest that Terasen® may improve the lifespan in C. elegans, warranting further investigation.","PeriodicalId":73588,"journal":{"name":"Journal of ageing and longevity","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139267798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The current study will explore the post-pandemic bereavement window of widowed caregivers who experienced higher degrees of social isolation and the ways in which leisure was used to cope. A phenomenological multi-case study technique was used to explore the “multiple realities” among female caregivers whose social convoys suffered pre-pandemic because of spousal caregiving and were further impacted by COVID-19 mitigation strategies during the pandemic. Initial analyses utilized the two-cycle approach, as defined by Saldana. In the initial cycle, the researchers independently immersed themselves in the raw data gathered during participant interviews and engaged in open coding to discern concepts, patterns, themes, and categories associated with the multiple realities among the widows whose leisure participation was affected due to the strain of spousal caregiving and exacerbated by COVID-19 mitigation strategies. After completing the first cycle, the researchers then moved to the second phase, thematic analysis, which sought to develop a more structured framework by which to understand the data by identifying, analyzing, and reporting patterns (e.g., themes) within it. A qualitative comparison technique was then employed to deepen our understanding of individuals’ lived experiences. Thematic findings revealed three areas of similarities: Social isolation from caregiving, using leisure to self-focus and explore future possibilities, and core groups.
{"title":"Examining the Role of Leisure in Navigating Spousal Death: A Phenomenological Multi-Case Study of Widowhood","authors":"Thomas P. Sweeney, Jennifer Zorotovich","doi":"10.3390/jal3040021","DOIUrl":"https://doi.org/10.3390/jal3040021","url":null,"abstract":"The current study will explore the post-pandemic bereavement window of widowed caregivers who experienced higher degrees of social isolation and the ways in which leisure was used to cope. A phenomenological multi-case study technique was used to explore the “multiple realities” among female caregivers whose social convoys suffered pre-pandemic because of spousal caregiving and were further impacted by COVID-19 mitigation strategies during the pandemic. Initial analyses utilized the two-cycle approach, as defined by Saldana. In the initial cycle, the researchers independently immersed themselves in the raw data gathered during participant interviews and engaged in open coding to discern concepts, patterns, themes, and categories associated with the multiple realities among the widows whose leisure participation was affected due to the strain of spousal caregiving and exacerbated by COVID-19 mitigation strategies. After completing the first cycle, the researchers then moved to the second phase, thematic analysis, which sought to develop a more structured framework by which to understand the data by identifying, analyzing, and reporting patterns (e.g., themes) within it. A qualitative comparison technique was then employed to deepen our understanding of individuals’ lived experiences. Thematic findings revealed three areas of similarities: Social isolation from caregiving, using leisure to self-focus and explore future possibilities, and core groups.","PeriodicalId":73588,"journal":{"name":"Journal of ageing and longevity","volume":"121 25","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136351747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-05DOI: 10.47855/jal9020-2023-3-3
Olena Tomarevska, Oleksandr Poliakov
For a general health assessment of the workers in organized industries, and unorganized groups of the unemployed and retirees, systematic online health monitoring has been used. Health monitoring includes a scale assessment of functional tests. The actual state of population health is still not included in the registers of National Statistics of Ukraine for example workers, pensioners and unemployment. The purpose of the study was systemic online health monitoring, to assess the impact of professional, demographic, and socio-economic factors in the Covid-19 pandemic condition and the limited capacity of the health care system in Ukraine. Methods: The study used the intrinsic capacity assessment scales, the five-question scale to detect muscle dysfunction in older persons, as well as some questions regarding residual performance, psychophysiological methods, and characteristics of the functional age. The questionnaire Human Health Passport 1.1 includes 70 questions; 21 of them were assessed by 1 point for positive answer and zero for negative case. The screening was carried out online on social media to Internet users aged 31 to 90. In the study 377 respondents of which 83.83% were employees. The Human Health Passport screening showed reliability (Cronbach alfa = 0.737), and correlation relationships of the main estimated indicators are significant. So, 54% of respondents do need health care under a physician’s supervision. The 39% of respondents need should convey the proper individual schedule of workout and labour hours, as well as physical activity and breathing exercises because only 7% of respondents are healthy. Correlation analysis of the scale results showed a significant relationship between age, with static balancing, falls during the last 6 months, and the ability to 5 times sit to stand test within 14 seconds. The optimal management of Human Health Passport screening helps to reduce the harmful influence on the environment, and transport expenses for doctor visits and saves the doctor's time for patient examination and prevention of the exposure and the spread of COVID-19. The screening showed the existing reserves of training for health promotion and, the overstrain of the functional systems of the body in the working population - 76%—by the purpose. _________________________________________________________________________________________ Keywords: remote health screening; retirees; biological age; ageing; elderly workers
{"title":"The Health and Functional Age Trend Self-assessment of the Older Workers and Retirees in Ukraine from Online Data Human Health Passport in COVID-19 Pandemic","authors":"Olena Tomarevska, Oleksandr Poliakov","doi":"10.47855/jal9020-2023-3-3","DOIUrl":"https://doi.org/10.47855/jal9020-2023-3-3","url":null,"abstract":"For a general health assessment of the workers in organized industries, and unorganized groups of the unemployed and retirees, systematic online health monitoring has been used. Health monitoring includes a scale assessment of functional tests. The actual state of population health is still not included in the registers of National Statistics of Ukraine for example workers, pensioners and unemployment. The purpose of the study was systemic online health monitoring, to assess the impact of professional, demographic, and socio-economic factors in the Covid-19 pandemic condition and the limited capacity of the health care system in Ukraine. Methods: The study used the intrinsic capacity assessment scales, the five-question scale to detect muscle dysfunction in older persons, as well as some questions regarding residual performance, psychophysiological methods, and characteristics of the functional age. The questionnaire Human Health Passport 1.1 includes 70 questions; 21 of them were assessed by 1 point for positive answer and zero for negative case. The screening was carried out online on social media to Internet users aged 31 to 90. In the study 377 respondents of which 83.83% were employees. The Human Health Passport screening showed reliability (Cronbach alfa = 0.737), and correlation relationships of the main estimated indicators are significant. So, 54% of respondents do need health care under a physician’s supervision. The 39% of respondents need should convey the proper individual schedule of workout and labour hours, as well as physical activity and breathing exercises because only 7% of respondents are healthy. Correlation analysis of the scale results showed a significant relationship between age, with static balancing, falls during the last 6 months, and the ability to 5 times sit to stand test within 14 seconds. The optimal management of Human Health Passport screening helps to reduce the harmful influence on the environment, and transport expenses for doctor visits and saves the doctor's time for patient examination and prevention of the exposure and the spread of COVID-19. The screening showed the existing reserves of training for health promotion and, the overstrain of the functional systems of the body in the working population - 76%—by the purpose. _________________________________________________________________________________________ Keywords: remote health screening; retirees; biological age; ageing; elderly workers","PeriodicalId":73588,"journal":{"name":"Journal of ageing and longevity","volume":"94 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135724413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01DOI: 10.47855/jal9020-2023-3-2
Vitalii Kyryk, Alina Ustymenko, Oleg Tsupykov
The review analyses modern scientific research on the impact of adipose tissue dysfunction associated with ageing on the morphofunctional characteristics of adipose-derived stem cells. Ageing in the body is accompanied by dysfunction in all tissues and organs, including adipose tissue, where changes in stem cells and their niche are associated with chronic systemic inflammation and metabolic disorders. Changes in stem cells induced by ageing-associated pathologies can affect both the effectiveness of endogenous tissue repair and the functional characteristics of the cell product. Increased production of pro-inflammatory cytokines and a decrease in the production of anti-inflammatory mediators and growth factors, accompanied by enhanced cellular infiltration, characterised as a senescence-associated secretory phenotype (SASP). SASP impact the potential of adipose-derived stem cells for proliferation, differentiation, signalling and even inducing apoptosis in recipient tissue after transplantation. The establishing characteristics of senescent cell cultures will provide new insights into the mechanisms of ageing and identify promising directions for its correction, including the clinical application of cell technologies. Special attention should be given to developing new approaches to assessing not only the quality and safety of cell products but also the functional state of niches in the recipient's body, which will represent a new strategy in personalized regenerative medicine. _________________________________________________________________________________________ Keywords: adipose-derived stem cells; multipotent mesenchymal stromal cells; cell differentiation; cell therapy; ageing
{"title":"The effect of ageing on the properties of adipose-derived stem cells. Literature review","authors":"Vitalii Kyryk, Alina Ustymenko, Oleg Tsupykov","doi":"10.47855/jal9020-2023-3-2","DOIUrl":"https://doi.org/10.47855/jal9020-2023-3-2","url":null,"abstract":"The review analyses modern scientific research on the impact of adipose tissue dysfunction associated with ageing on the morphofunctional characteristics of adipose-derived stem cells. Ageing in the body is accompanied by dysfunction in all tissues and organs, including adipose tissue, where changes in stem cells and their niche are associated with chronic systemic inflammation and metabolic disorders. Changes in stem cells induced by ageing-associated pathologies can affect both the effectiveness of endogenous tissue repair and the functional characteristics of the cell product. Increased production of pro-inflammatory cytokines and a decrease in the production of anti-inflammatory mediators and growth factors, accompanied by enhanced cellular infiltration, characterised as a senescence-associated secretory phenotype (SASP). SASP impact the potential of adipose-derived stem cells for proliferation, differentiation, signalling and even inducing apoptosis in recipient tissue after transplantation. The establishing characteristics of senescent cell cultures will provide new insights into the mechanisms of ageing and identify promising directions for its correction, including the clinical application of cell technologies. Special attention should be given to developing new approaches to assessing not only the quality and safety of cell products but also the functional state of niches in the recipient's body, which will represent a new strategy in personalized regenerative medicine. _________________________________________________________________________________________ Keywords: adipose-derived stem cells; multipotent mesenchymal stromal cells; cell differentiation; cell therapy; ageing","PeriodicalId":73588,"journal":{"name":"Journal of ageing and longevity","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135220992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amy Beardmore, Penny Beynon, Christine Crabbe, Jan Fullforth, Jeremy Groome, Matthew Jones
Background: Whilst qualitative research has previously been conducted on older people’s personal resilience and wellbeing during COVID-19, there are fewer empirical studies on the impact it had on social connectedness for this age group. In this paper we seek to examine older people’s social connectedness to others during the pandemic, their personal experiences of seeking out those connections, and whether there are any identifiable pre-existing factors that enabled them to minimise the impact of enforced isolation. Methods: Using a phenomenological methodology, we conducted in-depth interviews with 13 older people between March and May 2021. These interviews explored the participant’s lived experiences of staying socially connected to others during the enforced lockdowns and various restrictions. Results: Our findings reveal strong themes of personal resilience, sense of coherence and other protective factors, but also highlight the benefits of establishing connections to friends, family, organised groups and community prior to the pandemic. Conclusion: Older people’s ability to stay socially connected is influenced by personal resilience and a positive mindset; pre-existing social ties to others and maintaining a personal sense of coherence and a sense of belonging to people or places. Our findings shed light on the importance of informal social interactions, what it means to feel lonely in older age and indicate that for some the pandemic restrictions may even have offered a welcome space in which to process significant life events.
{"title":"Social Connectedness in a Locked-Down World: A Phenomenological Study of Older Adults during the COVID-19 Pandemic","authors":"Amy Beardmore, Penny Beynon, Christine Crabbe, Jan Fullforth, Jeremy Groome, Matthew Jones","doi":"10.3390/jal3040020","DOIUrl":"https://doi.org/10.3390/jal3040020","url":null,"abstract":"Background: Whilst qualitative research has previously been conducted on older people’s personal resilience and wellbeing during COVID-19, there are fewer empirical studies on the impact it had on social connectedness for this age group. In this paper we seek to examine older people’s social connectedness to others during the pandemic, their personal experiences of seeking out those connections, and whether there are any identifiable pre-existing factors that enabled them to minimise the impact of enforced isolation. Methods: Using a phenomenological methodology, we conducted in-depth interviews with 13 older people between March and May 2021. These interviews explored the participant’s lived experiences of staying socially connected to others during the enforced lockdowns and various restrictions. Results: Our findings reveal strong themes of personal resilience, sense of coherence and other protective factors, but also highlight the benefits of establishing connections to friends, family, organised groups and community prior to the pandemic. Conclusion: Older people’s ability to stay socially connected is influenced by personal resilience and a positive mindset; pre-existing social ties to others and maintaining a personal sense of coherence and a sense of belonging to people or places. Our findings shed light on the importance of informal social interactions, what it means to feel lonely in older age and indicate that for some the pandemic restrictions may even have offered a welcome space in which to process significant life events.","PeriodicalId":73588,"journal":{"name":"Journal of ageing and longevity","volume":"21 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135265754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Although evidence-based programs have been effective for fall prevention in many communities, older adults living in underserved areas cannot access these services due to the shortage of providers and trainers. In this cross-sectional study, a multi-agency approach was adopted for integrating an evidence-based program, A Matter of Balance (AMOB), into the public health curriculum at a rurally placed university. We assessed student learning as well as the community benefits of fall prevention among those who participated in the AMOB program. Eighty-four percent of the students reported intentions of using AMOB training in their future careers. The average of the items for the effectiveness of “Classroom Training” and “Community Training” provided by the students (n = 25) ranged from 3.52 to 4.32 and 3.48 to 4.36, on a Likert scale (1 = Strongly Disagree to 5 = Strongly Agree), respectively. Older adults who participated in the fall prevention community workshops showed increased confidence in reducing falls, protecting themselves from falling, and becoming steadier on their feet after the training (p < 0.05). Our study demonstrates the value of integrating evidence-based programs such as AMOB in a university curriculum to address rural health disparities related to falls.
尽管基于证据的项目在许多社区预防跌倒方面很有效，但由于缺乏提供者和培训人员，生活在服务不足地区的老年人无法获得这些服务。在这项横断面研究中，采用多机构方法将基于证据的项目“平衡问题”(a Matter of Balance, AMOB)纳入一所农村大学的公共卫生课程。我们评估了参加AMOB项目的学生的学习情况以及预防跌倒的社区效益。84%的学生表示，他们打算在未来的职业生涯中使用AMOB培训。学生(n = 25)提供的“课堂培训”和“社区培训”有效性项目的平均值在李克特量表(1 =非常不同意到5 =非常同意)上分别为3.52至4.32和3.48至4.36。参加预防跌倒社区研讨会的老年人在减少跌倒、保护自己不跌倒和训练后变得更稳定方面表现出更大的信心(p <0.05)。我们的研究证明了在大学课程中整合AMOB等循证项目的价值，以解决与跌倒相关的农村健康差异。
{"title":"Empowering Older Adults in Underserved Communities—An Innovative Approach to Increase Public Health Capacity for Fall Prevention","authors":"Subi Gandhi, Laurie Long, Viraj Gandhi, Muna Bashir","doi":"10.3390/jal3040019","DOIUrl":"https://doi.org/10.3390/jal3040019","url":null,"abstract":"Although evidence-based programs have been effective for fall prevention in many communities, older adults living in underserved areas cannot access these services due to the shortage of providers and trainers. In this cross-sectional study, a multi-agency approach was adopted for integrating an evidence-based program, A Matter of Balance (AMOB), into the public health curriculum at a rurally placed university. We assessed student learning as well as the community benefits of fall prevention among those who participated in the AMOB program. Eighty-four percent of the students reported intentions of using AMOB training in their future careers. The average of the items for the effectiveness of “Classroom Training” and “Community Training” provided by the students (n = 25) ranged from 3.52 to 4.32 and 3.48 to 4.36, on a Likert scale (1 = Strongly Disagree to 5 = Strongly Agree), respectively. Older adults who participated in the fall prevention community workshops showed increased confidence in reducing falls, protecting themselves from falling, and becoming steadier on their feet after the training (p < 0.05). Our study demonstrates the value of integrating evidence-based programs such as AMOB in a university curriculum to address rural health disparities related to falls.","PeriodicalId":73588,"journal":{"name":"Journal of ageing and longevity","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135094297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract. This study aims to investigate changes in heart rate variability (HRV) in women with PTSD during the Russian-Ukrainian war, in 2023. The study included 16 women with PTSD (age 49.60 ± 1.46 years) and 31 women (control, age 52.10 ± 1.27 years) aged from 30 to 69 years old, who were examined. Blood pressure, heart rate and ECG measurements were taken in the supine positions (within 5 minutes). HRV scores were calculated in the time domain and frequency domain. In women with PTSD, there was significantly lower control in the values of SDNN and TP values, which characterize the total power of neurohumoral regulation of heart rate (p< 0.05). The baroreflex activity, assessed by the spectral power of low-frequency waves (LF), in women with PTSD did not change significantly compared to controls. The differences in the indicators characterizing vagal influences were especially pronounced: in women with PTSD, RMSSD, pNN50 and HF component of HRV were lower than in controls. The sympathovagal balance (LF/HF) in women with PTSD, compared with the control, is shifted towards the predominance of sympathetic activity. The average BA in the group of people with PTSD was 57.30±1.32 years and in the control group – 55.65 ± 0.97 years. The difference between BA and CA is 7.72±1.42 years in the women with PTSD and 3.55 ± 1.06 in the control group (p< 0.05). From this, we can conclude that PTSD can be a factor in accelerating ageing. The data obtained in our study allow us to conclude that PTSD may be a factor that disrupts autonomic regulation and accelerates ageing. _________________________________________________________________________________________ Keywords: heart rate variability, posttraumatic stress disorder, Ukraine 2023.
{"title":"Heart Rate Variability and Aging Rate in Women with Post-Traumatic Stress Disorder during Russian-Ukrainian War, 2023","authors":"Anatoly Pisaruk, Ivanna Antoniuk-Shcheglova, Ludmila Mekhova, Svitlana Naskalova, Valeri Shatilo","doi":"10.47855/jal9020-2023-3-1","DOIUrl":"https://doi.org/10.47855/jal9020-2023-3-1","url":null,"abstract":"Abstract. This study aims to investigate changes in heart rate variability (HRV) in women with PTSD during the Russian-Ukrainian war, in 2023. The study included 16 women with PTSD (age 49.60 ± 1.46 years) and 31 women (control, age 52.10 ± 1.27 years) aged from 30 to 69 years old, who were examined. Blood pressure, heart rate and ECG measurements were taken in the supine positions (within 5 minutes). HRV scores were calculated in the time domain and frequency domain. In women with PTSD, there was significantly lower control in the values of SDNN and TP values, which characterize the total power of neurohumoral regulation of heart rate (p< 0.05). The baroreflex activity, assessed by the spectral power of low-frequency waves (LF), in women with PTSD did not change significantly compared to controls. The differences in the indicators characterizing vagal influences were especially pronounced: in women with PTSD, RMSSD, pNN50 and HF component of HRV were lower than in controls. The sympathovagal balance (LF/HF) in women with PTSD, compared with the control, is shifted towards the predominance of sympathetic activity. The average BA in the group of people with PTSD was 57.30±1.32 years and in the control group – 55.65 ± 0.97 years. The difference between BA and CA is 7.72±1.42 years in the women with PTSD and 3.55 ± 1.06 in the control group (p< 0.05). From this, we can conclude that PTSD can be a factor in accelerating ageing. The data obtained in our study allow us to conclude that PTSD may be a factor that disrupts autonomic regulation and accelerates ageing. _________________________________________________________________________________________ Keywords: heart rate variability, posttraumatic stress disorder, Ukraine 2023.","PeriodicalId":73588,"journal":{"name":"Journal of ageing and longevity","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135815190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The global population has been gradually aging over the past few decades, with a growing proportion of people aged 65 years or older. Simultaneously, the medical profession has shifted towards promoting the concept of “positive” gerontology, emphasizing healthy aging. In this context, we investigated the trends in pathological specimen submissions from patients aged 85 or older over ten years at a single center. We observed a nearly two-fold increase in submissions during 2015–2019 compared to 2010–2014, out of proportion to the change in the fraction of older adults in the population, suggesting a changing attitude towards medical care in these older patients. Dermatologic samples were the main driver of growth, followed by gastrointestinal and urinary tract samples. However, other samples, like breast and lung, did not significantly increase. Although further research is needed to understand the implications of increasing invasive procedures in the oldest old, a noteworthy trend has emerged towards increased and more active healthcare for this population. Healthcare providers and administrators should be prepared for a continued rise in invasive interventions in this age group.
{"title":"Trends in Octogenarian Pathology","authors":"Tal Keidar Haran, Arnon Haran, N. Pillar","doi":"10.3390/jal3030018","DOIUrl":"https://doi.org/10.3390/jal3030018","url":null,"abstract":"The global population has been gradually aging over the past few decades, with a growing proportion of people aged 65 years or older. Simultaneously, the medical profession has shifted towards promoting the concept of “positive” gerontology, emphasizing healthy aging. In this context, we investigated the trends in pathological specimen submissions from patients aged 85 or older over ten years at a single center. We observed a nearly two-fold increase in submissions during 2015–2019 compared to 2010–2014, out of proportion to the change in the fraction of older adults in the population, suggesting a changing attitude towards medical care in these older patients. Dermatologic samples were the main driver of growth, followed by gastrointestinal and urinary tract samples. However, other samples, like breast and lung, did not significantly increase. Although further research is needed to understand the implications of increasing invasive procedures in the oldest old, a noteworthy trend has emerged towards increased and more active healthcare for this population. Healthcare providers and administrators should be prepared for a continued rise in invasive interventions in this age group.","PeriodicalId":73588,"journal":{"name":"Journal of ageing and longevity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47559477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahsa Sadatnia, Amir Jalali, Laili Tapak, F. Shamsaei
Background and Aim: The coronavirus pandemic has had a negative impact on the health and well-being of communities and individuals around the world. One of the concerns about the COVID-19 epidemic is the impact of social isolation due to social distancing on the mental health of older adults. This study aimed to investigate the relationship between mental health and loneliness among seniors during the COVID-19 pandemic. Materials and Methods: In this cross-sectional study, 211 retirees of Kermanshah University of Medical Sciences were selected by available sampling method in 2021. Data were collected through the Demographic, Mental Health Questionnaire (GHQ-28) and the Adult Social and Emotional Feeling Questionnaire (SELSA-S). Data were analyzed using paired t-test, one-way analysis of variance, covariance, and chi-squared tests. The significance level was considered 0.05. Results: The mean age of participants was 71.26 years and the results showed a significant relationship between feeling lonely and mental health (r = 0.535, p = 0.001). There were statistically significant relationships between mental health and social functioning (r = −0.204, p ≥ 0.001) and depression (r = 0.501, p = 0.001) and also between mental health and three subscales of loneliness: romantic loneliness (r = 0.001, p = 0.001), social loneliness (r = 0.493, p = 0.001), and family loneliness (r = 0.289, p = 0.001). Conclusion: Feeling lonely during the coronavirus disease pandemic has a negative effect on the mental health of older adults; therefore, it is necessary for mental health professionals to improve the mental health of the elderly with proper planning and interventions.
{"title":"The Relationship between Mental Health and Loneliness in the Elderly during the COVID-19 Pandemic","authors":"Mahsa Sadatnia, Amir Jalali, Laili Tapak, F. Shamsaei","doi":"10.3390/jal3030017","DOIUrl":"https://doi.org/10.3390/jal3030017","url":null,"abstract":"Background and Aim: The coronavirus pandemic has had a negative impact on the health and well-being of communities and individuals around the world. One of the concerns about the COVID-19 epidemic is the impact of social isolation due to social distancing on the mental health of older adults. This study aimed to investigate the relationship between mental health and loneliness among seniors during the COVID-19 pandemic. Materials and Methods: In this cross-sectional study, 211 retirees of Kermanshah University of Medical Sciences were selected by available sampling method in 2021. Data were collected through the Demographic, Mental Health Questionnaire (GHQ-28) and the Adult Social and Emotional Feeling Questionnaire (SELSA-S). Data were analyzed using paired t-test, one-way analysis of variance, covariance, and chi-squared tests. The significance level was considered 0.05. Results: The mean age of participants was 71.26 years and the results showed a significant relationship between feeling lonely and mental health (r = 0.535, p = 0.001). There were statistically significant relationships between mental health and social functioning (r = −0.204, p ≥ 0.001) and depression (r = 0.501, p = 0.001) and also between mental health and three subscales of loneliness: romantic loneliness (r = 0.001, p = 0.001), social loneliness (r = 0.493, p = 0.001), and family loneliness (r = 0.289, p = 0.001). Conclusion: Feeling lonely during the coronavirus disease pandemic has a negative effect on the mental health of older adults; therefore, it is necessary for mental health professionals to improve the mental health of the elderly with proper planning and interventions.","PeriodicalId":73588,"journal":{"name":"Journal of ageing and longevity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47253859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This paper is dedicated to the research presented at the 26th Nordic Congress of Gerontology in Odense, Denmark, in June 2022, which was organized by the Danish Gerontological Society and the Danish Society for Geriatrics. The overall topics of the congress were change and continuity. Participants were invited to explore questions on change and continuity from the perspective of ageing and later life within the following congress themes: digitisation and technology; housing, generations and mobility; lifestyle, engagement and transition; education and competences in ageing societies; morbidity, medical treatment and ageing processes; and a good life and a good death. Life is about change and continuity. We experience ourselves and our surroundings differently throughout our lives. For most people, later life is characterized by major transitions, moving towards frailty and multiple losses. But it may also be a part of life with more time to engage in preferred activities, explore new possibilities, and to cope and come to terms with new challenges. The COVID-19 pandemic proved to be a challenge to the world beyond imagination, particularly for frail and vulnerable people and societies. However, it also provided valuable new insights and reminded us of the values in life. We, therefore, also welcomed presentations and discussions on societal perspectives such as citizen perspective, ethnicity, inequality, sustainability and ecology, the pandemic and lockdown. We thank the organizers, scientific committees and all participants for a great congress with high-quality presentations and discussions.
{"title":"Abstracts from the 26th Nordic Congress of Gerontology","authors":"J. Thuesen, C. Nilsson, P. Caserotti","doi":"10.3390/jal3030016","DOIUrl":"https://doi.org/10.3390/jal3030016","url":null,"abstract":"This paper is dedicated to the research presented at the 26th Nordic Congress of Gerontology in Odense, Denmark, in June 2022, which was organized by the Danish Gerontological Society and the Danish Society for Geriatrics. The overall topics of the congress were change and continuity. Participants were invited to explore questions on change and continuity from the perspective of ageing and later life within the following congress themes: digitisation and technology; housing, generations and mobility; lifestyle, engagement and transition; education and competences in ageing societies; morbidity, medical treatment and ageing processes; and a good life and a good death. Life is about change and continuity. We experience ourselves and our surroundings differently throughout our lives. For most people, later life is characterized by major transitions, moving towards frailty and multiple losses. But it may also be a part of life with more time to engage in preferred activities, explore new possibilities, and to cope and come to terms with new challenges. The COVID-19 pandemic proved to be a challenge to the world beyond imagination, particularly for frail and vulnerable people and societies. However, it also provided valuable new insights and reminded us of the values in life. We, therefore, also welcomed presentations and discussions on societal perspectives such as citizen perspective, ethnicity, inequality, sustainability and ecology, the pandemic and lockdown. We thank the organizers, scientific committees and all participants for a great congress with high-quality presentations and discussions.","PeriodicalId":73588,"journal":{"name":"Journal of ageing and longevity","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48934687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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