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Predictors on mortality of human immunodeficiency virus infected children after initiation of antiretroviral treatment in Wolaita zone health facilities, Ethiopia: Retrospective cohort study 埃塞俄比亚Wolaita地区卫生机构开始抗逆转录病毒治疗后感染人类免疫缺陷病毒儿童死亡率的预测因素:回顾性队列研究
Pub Date : 2017-04-30 DOI: 10.5897/JAHR2016.0412
Shimelash Bitew, A. Mekonen, Meselech Assegid
Worldwide Human Immunodeficiency Virus/Acquired Immune Deficiency syndromes (HIV/AIDS) have created an enormous challenge on the survival of infected patients. Identifying baseline factors that predict morbidity could allow their possible modification in order to improve pediatric HIV care. Retrospective cohort study was conducted in 228 HIV infected children starting antiretroviral treatment at Wolaita zone selected health facilities, Ethiopia. WHO reference population was used to calculate Z- scores for height-for-age, weight-for-height, and weight-for-age. Data were analyzed by bivariate and multivariate analysis using Cox regression proportional hazard model. Survival were calculated and compared with the Kaplan Meier and log rank test. Males account 121(53.1%), mean age was 6.29 years. Mean survival time using Kaplan Meier analysis was 89.3 months (95% CI 85.71-92.97). Incidence of mortality rate 21.02 per 1000 person years of observation (95% CI 12.8-34.3). Overall nutritional status was, 62.5% stunted, 43.0% underweight and 44.7% wasted at baseline. As a result, rural residence AHR 4.30 (95% CI, 1.25-14.8), fair/poor of first three-month ART adherence AHR 8.95(95% CI 2.624-33.72), severely wasted children at baseline AHR 7.040 (95% CI, 1.27-39.13) and age of children were predictors of mortality. Mortality among HIV-infected children was high and strongly associated with malnutrition, residence in rural area, low adherence to ART, and beginning of ART at an advanced age; highlighting the urgent need for targeted interventions including promotion of early initiation and adherence to ART. Key words: Children, malnutrition, mortality, HIV/AIDS.
世界范围内的人类免疫缺陷病毒/获得性免疫缺陷综合征(HIV/AIDS)给感染患者的生存带来了巨大挑战。确定预测发病率的基线因素可以对其进行可能的修改,以改善儿科HIV护理。在埃塞俄比亚沃莱塔地区选定的卫生机构对228名开始接受抗逆转录病毒治疗的艾滋病毒感染儿童进行了回顾性队列研究。世界卫生组织参考人群用于计算身高、身高和年龄的Z值。采用Cox回归比例风险模型,通过双变量和多变量分析对数据进行分析。计算生存率,并与Kaplan-Meier和log秩检验进行比较。男性121例(53.1%),平均年龄6.29岁。Kaplan-Meier分析的平均生存时间为89.3个月(95%CI 85.71-92.97)。死亡率为21.02/1000人-年观察(95%CI 12.8-3.3)。总体营养状况为,基线时发育迟缓62.5%,体重不足43.0%,浪费44.7%。因此,农村居民AHR 4.30(95%CI,1.25-14.8)、前三个月抗逆转录病毒治疗依从性尚可/较差AHR 8.95(95%CI 2.624-33.72)、基线时严重消瘦儿童AHR 7.040(95%CI 1.27-39.13)和儿童年龄是死亡率的预测因素。感染艾滋病毒的儿童死亡率很高,与营养不良、居住在农村地区、抗逆转录病毒治疗依从性低以及高龄开始抗逆转录病毒疗法密切相关;强调迫切需要有针对性的干预措施,包括促进早期开始和坚持抗逆转录病毒疗法。关键词:儿童、营养不良、死亡率、艾滋病毒/艾滋病。
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引用次数: 8
Efficacy of amaranth grain consumption on CD4 count and morbidity patterns among adults living with HIV in Nyeri, Kenya 在肯尼亚尼耶里,苋菜谷物消费对艾滋病毒感染者CD4计数和发病率模式的影响
Pub Date : 2017-04-30 DOI: 10.5897/JAHR2017.0415
Z. Ndungu, E. Kuria, N. Gikonyo, D. Mbithe
Human immunodeficiency virus (HIV) is associated with increased nutrient needs and compromised body immunity. Minimal information exists on effect of food-based interventions on health status of people living with HIV (PLHIV) and not on antiretroviral therapy (ART). This study investigated the efficacy of amaranth grain (Amaranthus cruentus) consumption on CD4 count and morbidity patterns among PLHIV. A one group pre-test-post-test study design was used on a sample of 66 pre-ART adults living with HIV. The study involved collection of baseline characteristics of the respondents; this was followed by consumption of amaranth grain porridge (100 g) for six months. Post-test data was collected and paired t- test was used to compare pre-test and post-test data. Daily consumption of 100 g of amaranth grain porridge increased nutrient intake. A significant increase (P=0.004) in CD4 count from 498.2±163 SD at baseline to 608 ± 157 SD post-test was observed. There was a significant decline in the number of respondents with any form of illnesses from a total of 52 (78.8%) at baseline to 21 (31.8%) respondents at month six (P=0.031). Amaranth grain increased nutrient intake, CD4 count and consequently reduced the prevalence of illness. The study recommends that nutrition and health practitioners should educate PLHIV on importance of use of amaranth grain to complement usual dietary intake. Key words: Amaranth grain, CD4 count, morbidity pattern, people living with human immunodeficiency virus (PLHIV).
人体免疫缺陷病毒(HIV)与营养需求增加和身体免疫力受损有关。关于基于食物的干预措施对艾滋病毒感染者健康状况的影响,而不是对抗逆转录病毒疗法的影响,信息很少。本研究调查了食用苋粒对PLHIV患者CD4计数和发病模式的影响。一组试验前试验后研究设计用于66名艾滋病病毒携带者的ART前成人样本。该研究涉及收集受访者的基线特征;随后食用苋粒粥(100g)6个月。收集测试后数据,并使用配对t检验来比较测试前和测试后的数据。每天食用100克的苋粒粥可以增加营养素的摄入。观察到CD4计数从基线时的498.2±163 SD显著增加(P=0.004)到测试后的608±157 SD。患有任何形式疾病的受访者数量显著下降,从基线时的52人(78.8%)下降到第六个月时的21人(31.8%)(P=0.031)。苋粒增加了营养摄入和CD4计数,从而降低了疾病的患病率。该研究建议营养和健康从业者应教育PLHIV使用苋粒补充日常饮食摄入的重要性。关键词:苋粒,CD4计数,发病模式,人类免疫缺陷病毒(PLHIV)感染者。
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引用次数: 3
Level of micronutrient supplements uptake among people living with HIV/AIDS in Kayole, Nairobi County, Kenya 肯尼亚内罗毕县Kayole地区艾滋病毒/艾滋病感染者微量营养素补充剂的摄取水平
Pub Date : 2017-04-30 DOI: 10.5897/JAHR2017.0414
P. Chege, O. Muthamia
Micronutrients reduce morbidity and slow the rate of disease progression and thus, micronutrient supplementation in HIV is recommended. This study established the level of uptake of micronutrient supplements among people living with HIV in Kayole, Nairobi County. A cross-sectional analytical design was adopted on a comprehensive sample of 153 adults living with HIV, enrolled at Comprehensive Care Centre in Kayole Health Centre. Data is described by use of percentages while relationships are assessed using chi-square. Qualitative data from focus group discussions and key informants was transcribed and analyzed to complement the quantitative findings. Results showed that only 13.7% of the respondents were on micronutrients at the time of the study. The micronutrient supplements commonly supplemented were vitamin and mineral mix (50.3%), zinc (34%), vitamin B6 (24.2%), vitamin A (24.2%), folate (12.4%), and iron (15%). The main reason for supplementation was; those on Antiretroviral Therapy (66.7%), due to the presence of opportunistic infections (40.5%), those who had no appetite (28.1%), underweight cases (21.6%) and those on tuberculosis treatment (17.0%). The main reason for low uptake was due to stock outs at treatment centre (24.8%), the high cost of supplements (13.7%) and side effects after intake (5.9%). Adults living with HIV are aware of the importance of micronutrients and had taken micronutrient supplements at one point during the treatment period.  However, uptake at the time of the study was low. This was due to lack of guidelines for supplementation, high cost of supplements, stock-outs in health facilities and side effects. This study recommends proper education and sensitization on supplementation. Standard guidelines and policies for micronutrient supplementation should be developed. A pull system should be adapted in the supply of supplements.   Key words: Micronutrients, supplementation, people living with HIV, Kenya, adults.
微量营养素可降低发病率并减缓疾病进展速度,因此,建议艾滋病毒患者补充微量营养素。本研究确定了内罗毕县卡约勒艾滋病毒感染者对微量营养素补充剂的摄取水平。对在Kayole卫生中心综合护理中心登记的153名成年艾滋病毒感染者采用了横断面分析设计。数据用百分比来描述,而关系用卡方来评估。来自焦点小组讨论和关键线人的定性数据被转录和分析,以补充定量结果。结果显示,只有13.7%的受访者在研究时服用了微量营养素。常见的微量营养素补充剂为维生素和矿物质混合物(50.3%)、锌(34%)、维生素B6(24.2%)、维生素A(24.2%)、叶酸(12.4%)和铁(15%)。补充的主要原因是;接受抗逆转录病毒治疗者(66.7%)、出现机会性感染者(40.5%)、食欲不振者(28.1%)、体重过轻者(21.6%)和接受结核病治疗者(17.0%)。摄取率低的主要原因是治疗中心缺货(24.8%)、补品费用高(13.7%)和摄入后的副作用(5.9%)。成年艾滋病毒感染者意识到微量营养素的重要性,并在治疗期间曾一度服用微量营养素补充剂。然而,在研究期间,摄取率很低。这是由于缺乏补充剂指南、补充剂费用高、保健设施缺货和副作用。本研究建议对补充剂进行适当的教育和宣传。应当制定补充微量营养素的标准准则和政策。补品的供应应采用拉制。关键词:微量元素,补充,艾滋病病毒感染者,肯尼亚,成年人
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引用次数: 3
Determinant factors of HIV positive status disclosure among adults in Axum Health Facilities, Northern Ethiopia: Implication on treatment adherence 埃塞俄比亚北部Axum卫生机构成年人HIV阳性状况披露的决定因素:对治疗依从性的影响
Pub Date : 2017-03-31 DOI: 10.5897/JAHR2016.0402
Haileselasie Berhane Alema, Kebede Haile Misgina, M. Weldu
Disclosure of HIV positive status to sexual partners, friends or relatives is crucial for HIV prevention and care implementation strategies. Hence, it is important to explore factors determining individuals to disclose their HIV positive status in order to achieve a goal of zero new HIV infection. Facility based mixed cross-sectional study was conducted from July to August, 2013 among 361 HIV positive adults attending Axum Health Facilities. They were selected through systematic random sampling. Data were collected by trained counselors and ART nurses and then entered into SPSS version 20 databases. Bivariate and multivariable logistic regression models were used to identify predictors of HIV positive status disclosure at 95% confidence intervals and p-value of less than 0.05. Among 361 respondents, 289 disclosed their HIV status to someone and 151(41.8%) to intimate partners. In the multivariate logistic regression analysis, variables significantly associated at p-value <0.05 were married; knowing partner’s HIV status and membership in an HIV-Support Group were positive predictors of disclosure. These findings were supported by qualitative study in which fear of discrimination,   fear of breaking confidentiality and fear of families make them to conceal their status. The rate of HIV positive status disclosure among HIV positive adults has remained low. Marital status of respondents, knowledge of partners’ HIV status and being member in Anti- HIV/AIDS Association were identified as predictors of HIV positive status disclosure. Addressing the issues of disclosure was recommended to encourage free disclosure and coping with negative reactions, which is a crucial way for adherence to treatment. Key words:  Adult, Axum health facilities, Ethiopia, HIV positive disclosure.
向性伴侣、朋友或亲属披露艾滋病毒阳性状况对于艾滋病毒预防和护理实施战略至关重要。因此,重要的是探索决定个人披露其艾滋病毒阳性状态的因素,以实现零新增艾滋病毒感染的目标。2013年7月至8月,在Axum卫生机构的361名HIV阳性成年人中进行了基于设施的混合横断面研究。他们是通过系统随机抽样选出的。数据由受过培训的咨询师和ART护士收集,然后输入SPSS 20版数据库。在95%置信区间和p值小于0.05的情况下,使用双变量和多变量逻辑回归模型来确定HIV阳性状态披露的预测因素。在361名受访者中,289人向某人透露了自己的艾滋病毒状况,151人(41.8%)向亲密伴侣透露了自己。在多变量逻辑回归分析中,p值<0.05显著相关的变量为已婚;了解伴侣的HIV状况和HIV支持小组的成员身份是披露的积极预测因素。这些发现得到了定性研究的支持,在该研究中,对歧视的恐惧、对保密的恐惧和对家庭的恐惧使他们隐瞒自己的身份。艾滋病毒阳性成年人中艾滋病毒阳性状况的披露率仍然很低。受访者的婚姻状况、对伴侣HIV状况的了解以及是否是抗HIV/AIDS协会的成员被确定为HIV阳性状况披露的预测因素。建议解决披露问题,以鼓励自由披露和应对负面反应,这是坚持治疗的关键方式。关键词:成人,Axum卫生设施,埃塞俄比亚,HIV阳性披露。
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引用次数: 5
Factors affecting adherence to antiretroviral treatment among patients living with HIV/AIDS, in Bale zone, south eastern Ethiopia 埃塞俄比亚东南部贝尔地区影响艾滋病毒/艾滋病患者坚持抗逆转录病毒治疗的因素
Pub Date : 2017-03-31 DOI: 10.5897/JAHR2016.0407
M. Beshir, Adamu Tesfaye
Adherence to antiretroviral therapy is of critical importance because even minor deviations from the prescribed regimen can result in viral resistance. Multiple factors influence adherence among people living with human immune virus. But at present little is known about the patient’s experience and adherence when taking such complex regimens. The major aim of the study was to assess factors associated with antiretroviral treatment adherence among people living with human immune virus  A facility based cross-sectional study design was used, with systematic sampling technique on 300 adult patients on antiretroviral therapy. Factors associated with adherence to antiretroviral drugs were analyzed with bivariate and multivariate logistic regression. A total of 300 patients on antiretroviral therapy involved in this research and despite requirement of complete or near complete adherence to antiretroviral therapy only 205(68.3%) were found to be adherent. The bivariate and multivariate logistic regression showed that factors like mild depression (AOR=3.24) 95% CI(2.04-8.67), moderate depression (AOR=3.06) 95%CI(1.61-5.67), alcohol abuse (COR=2.562) p=0.049, current khat chewing (COR=2.85) p=0.025, disclosure status (COR=0.426) p=0.004, presence of opportunistic infection (AOR=5.44) 95%CI(1.833-16.10), and presence of comorbid disease (COR=4.256) p=0.002 showed association to adherence to antiretroviral therapy. Generally about three out ten patients on antiretroviral therapy were found to be non-adherent to antiretroviral regimen in Bale zone. Depression and the presence of opportunistic infection are adversely linked to adherence status of these patients. Key words: Adherence, highly active antiretroviral therapy (HAART), ART Clinic, Bale.
坚持抗逆转录病毒治疗是至关重要的,因为即使是对规定方案的轻微偏差也可能导致病毒耐药性。多种因素影响人类免疫病毒感染者的依从性。但目前对患者的经历和服用这种复杂疗法的依从性知之甚少。该研究的主要目的是评估与人类免疫病毒感染者抗逆转录病毒治疗依从性相关的因素。采用基于设施的横断面研究设计,采用系统抽样技术对300名接受抗逆转录病毒治疗的成年患者进行了研究。采用双变量和多变量logistic回归分析与抗逆转录病毒药物依从性相关的因素。本研究共有300名接受抗逆转录病毒治疗的患者,尽管要求完全或接近完全坚持抗逆转录病毒治疗,但仅发现205名(68.3%)患者坚持治疗。双因素和多因素logistic回归分析显示,轻度抑郁(AOR=3.24) 95%CI(2.04 ~ 8.67)、中度抑郁(AOR=3.06) 95%CI(1.61 ~ 5.67)、酗酒(COR=2.562) p=0.049、当前咀嚼阿拉伯茶(COR=2.85) p=0.025、信息披露状态(COR=0.426) p=0.004、存在机会性感染(AOR=5.44) 95%CI(1.833 ~ 16.10)、存在共病(COR=4.256) p=0.002等因素与抗逆转录病毒治疗依从性相关。一般来说,在贝尔地区,接受抗逆转录病毒治疗的患者中,约有十分之三的人不坚持抗逆转录病毒治疗方案。抑郁和机会性感染的存在与这些患者的依从状态呈负相关。关键词:依从性;高效抗逆转录病毒治疗(HAART); ART诊所;
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引用次数: 1
Cross border migration enhancing reproductive vulnerability of the left behind women and their coping mechanism through self help groups: A study of Bangladesh 跨境移民通过自助团体增强留守妇女的生殖脆弱性及其应对机制:对孟加拉国的研究
Pub Date : 2017-03-31 DOI: 10.5897/JAHR2016.0390
S. Singh, A. Siddhanta
This study analyzes the range of vulnerabilities among the left behind women (LBW) and their coping strategies primarily focusing on Self Help Groups (SHGs). The basic data used in this paper were collected as part of the Mid Term Review of a cross country intervention on Enhancing Mobile Populations’ Access to HIV&AIDS Services, Information and Support (EMPHASIS) in South Asia in 2012. The reproductive vulnerabilities of the left behind women like sexually transmitted infections (STIs), reproductive tract infections (RTIs), human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) are primarily due to the risky sexual behaviour of husbands at destination. The other vulnerabilities faced by the left behind women are the lack of capacity in treatment seeking, physical harassments and social vulnerabilities with the blind administrative response. The self-help groups have proved to be a boon in the life of these left behind women in Bangladesh and have also moulded their lives for beneficence. Compared to their previous lives without the association of self-help groups, left behind women can now address their vulnerability to HIV/AIDS and impart this knowledge to their husband and ask them to abstain from sex in India or to have safe sex with female sex workers (FSWs). Self help groups also have impacted their social and financial positions reducing social harassment. The mobility of the left behind women has increased in and outside community improving their treatment seeking behaviour. They have now become literate about their sexual and reproductive rights and negotiate with their husbands to use condoms when they come back. Key words: Left behind women, cross border migration, Bangladesh, reproductive vulnerability, HIV & AIDS.
本研究分析了留守妇女的脆弱性范围及其应对策略,主要关注自助群体。本文中使用的基本数据是作为2012年南亚加强流动人口获得艾滋病毒/艾滋病服务、信息和支持的跨国家干预措施中期审查的一部分收集的。留守妇女的生殖脆弱性,如性传播感染、生殖道感染、人体免疫缺陷病毒/后天免疫缺陷综合征,主要是由于丈夫在目的地的危险性行为。留守妇女面临的其他脆弱性是缺乏寻求治疗的能力、身体骚扰和盲目的行政反应造成的社会脆弱性。事实证明,自助团体为孟加拉国这些留守妇女的生活带来了福音,也塑造了她们的慈善生活。与以前没有自助团体的生活相比,留守妇女现在可以解决她们易感染艾滋病毒/艾滋病的问题,并将这一知识传授给丈夫,并要求她们在印度禁欲或与女性性工作者进行安全的性行为。自助团体也影响了他们的社会和财务状况,减少了社会骚扰。留守妇女在社区内外的流动性增加,改善了她们寻求治疗的行为。她们现在已经了解了自己的性权利和生殖权利,并与丈夫协商在回来时使用避孕套。关键词:留守妇女、跨境移民、孟加拉国、生殖脆弱性、艾滋病毒和艾滋病。
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引用次数: 0
Factors associated with HIV testing among female sex workers in Botswana 博茨瓦纳女性性工作者中艾滋病毒检测的相关因素
Pub Date : 2017-02-28 DOI: 10.5897/JAHR2016.0404
K. Setlhare, G. D. Manyeagae
Botswana continues to have a high level of HIV prevalence, with about 17% of the population living with HIV AIDS (BAIS IV, 2013). Female sex workers are classified among the most at risk population group in the country. However, sub-national disaggregated data on new infections are not available. Hence, there is a need to focus great attention on other proxies of infection. The present study examines predictors of HIV testing among female sex workers (FSWs) in Botswana. The FSWs were recruited into the study using the time-location cluster sampling method (TLS) to collect data on prevalence and incidence of HIV and other STIs and their risk factors for HIV. The logistic regression analysis was performed to estimate crude odds ratios and identify the factors associated with having an HIV test among the FSWs. HIV prevalence among sex workers in Botswana was found to be 3 times higher than in the general population. Analysis of the results shows that the sex workers most likely to seek HIV testing were young women with no children. The odds of testing for HIV were almost 4 times more for FSWs who had first sex older as compared to the odds of testing for those who are 17 to 19 years old. Lack of or inconsistent condom use and currently having symptoms of STIs such as lower abdominal pain and genital ulcerations were also factors associated with HIV testing. Results further show that FSW hold little discrimination and stigma related attitudes towards PLWA. FSWs have little participation in the HIV prevention, treatment and care efforts currently accessed by the general population. It is recommended is that this framework should also be extended to FSW’s and their clients in order to curb HIV and STIs. Key words: Female sex workers, HIV testing, Botswana, prevalence, associated factors, odds ratio.
博茨瓦纳的艾滋病毒感染率仍然很高,约17%的人口患有艾滋病毒/艾滋病(BAIS IV,2013)。女性性工作者被列为该国风险最大的人群之一。然而,没有关于新感染病例的按次国家分类的数据。因此,有必要高度关注感染的其他指标。本研究调查了博茨瓦纳女性性工作者(FSW)HIV检测的预测因素。FSW被招募到研究中,使用时间-地点-聚类抽样方法(TLS)来收集有关HIV和其他性传播感染的流行率和发病率及其HIV风险因素的数据。进行逻辑回归分析,以估计FSW中的粗略比值比,并确定与HIV检测相关的因素。博茨瓦纳性工作者中的艾滋病毒感染率是普通人群的3倍。对结果的分析表明,最有可能寻求艾滋病毒检测的性工作者是没有孩子的年轻女性。与17至19岁的女性进行艾滋病毒检测的几率相比,年龄较大的第一次性行为的女性工作人员的艾滋病毒检测几率几乎高出4倍。缺乏或不一致使用避孕套以及目前有下腹疼痛和生殖器溃疡等性传播感染症状也是与艾滋病毒检测相关的因素。结果进一步表明,FSW对PLWA几乎没有歧视和污名化相关的态度。FSW很少参与普通人群目前获得的艾滋病毒预防、治疗和护理工作。建议将这一框架扩展到FSW及其客户,以遏制艾滋病毒和性传播感染。关键词:女性性工作者,艾滋病毒检测,博茨瓦纳,流行率,相关因素,比值比。
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引用次数: 4
Assessment of the workplace programme for HIV/AIDS in the tourism industry sector of Namibia 评价纳米比亚旅游业部门艾滋病毒/艾滋病工作场所方案
Pub Date : 2017-02-28 DOI: 10.5897/JAHR2016.0403
M. Y. Teweldemedhin, J. Swartz, Erling Kavita, A. Siebert
The aim of this paper was to assess the Work Place Programme (WPP) for HIV/AIDS in Namibia. The methodological framework consisted of the following stages: (i) defining the target population, (ii) clustering the producers, (iii) applying the selection criteria and (iv) applying the eligibility criteria. Data analysis involved descriptive and inferential statistical procedures, as well as the triangulation of data. The study was conducted in Namibia, in the capital city of Windhoek and the city of Swakopmund, which is a tourist hub between the desert and the coastline. The results show that of the 108 companies sampled, none had a WPP in place, while a few had some undocumented HIV/AIDS activities. Companies indicated that WPP implementation strategies had been inactive for long periods of time and that many HIV and AIDS activities were centered on World Aids Day. This was attributed to budgetary constraints; there is perception that such programmes are the responsibility of the government. This prevented such programmes from featuring in the business’s strategic planning and not yet mainstreamed into company operations. This study suggested that effective HIV and AIDS policy need to integrate within the context of corporate social responsibility (CSR), is essential for adequate health care management in the tourism industry. Key words: Policy, corporate social responsibility (CSR), Work Place Programme (WPP), HIV/AIDS, Namibia.
本文的目的是评估纳米比亚艾滋病毒/艾滋病工作场所方案(WPP)。方法框架包括以下阶段:(i)确定目标人群,(ii)聚集生产者,(iii)应用选择标准和(iv)应用资格标准。数据分析包括描述性和推断性统计程序,以及数据的三角测量。这项研究是在纳米比亚的首都温得和克和斯瓦科普蒙德进行的,斯瓦科普蒙德是沙漠和海岸线之间的旅游中心。结果显示,在108家抽样公司中,没有一家公司有WPP,而少数公司有一些没有记录的艾滋病毒/艾滋病活动。各公司指出,WPP的执行战略长期以来一直没有发挥作用,许多艾滋病毒和艾滋病活动都以世界艾滋病日为中心。这是由于预算限制;有一种看法认为,此类计划是政府的责任。这使得这些计划无法在企业的战略规划中发挥重要作用,也无法成为公司运营的主流。该研究表明,有效的艾滋病毒和艾滋病政策需要在企业社会责任(CSR)的背景下进行整合,这对于旅游业的适当卫生保健管理至关重要。关键词:政策,企业社会责任,工作场所计划,艾滋病,纳米比亚
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引用次数: 0
A study on HIV knowledge and preventive behavioral practices among FSWS in Mumbai 孟买FSWS人群艾滋病知识和预防行为研究
Pub Date : 2017-01-31 DOI: 10.5897/JAHR2016.0398
G. Adithyan, Bal Rakshase, A. Ekstrom
The prevalence of HIV among female sex workers (FSW) in India is highest in the state of Maharashtra (7.4%). Mumbai, the capital city of Maharashtra, with a large sex industry mainly consisting of brothels, lags behind in the overall average decline in HIV seen in this state over the last decade. Condoms are now widely used by sex workers through the pro-active role of Mumbai District AIDS Control Society (MDACS) and many non-governmental organizations (NGOs), but many associated risk behaviours remain and contribute to the high HIV prevalence among FSW in Mumbai. This community-based descriptive study was conducted to assess HIV/AIDS-related knowledge and sexual risk behaviours among FSW in Mumbai in 2015. Knowledge was assessed using a ‘cumulative knowledge score’ by taking 18 questions to assess HIV/AIDS knowledge. Sexual behavioural practises among FSW with occasional clients, regular male clients, regular non-paying male partner and non-regular non-paying clients were also assessed separately. Ninety-one FSW working in brothels in Mumbai gave informed consent and were purposively selected to participate in the study. The mean age of the respondents was 32.9, three out of four were illiterate and 62% were either married or had a live-in partner. 85% of the study population reported above average satisfactory score (score≥8) on cumulative knowledge on HIV/AIDS and a nearly 100% used condom both with regular and occasional clients. The study revealed some risk factors among FSW and their regular non-paying partners that need to be urgently tackled. Most of the FSW (86%) use more than one condom during a sexual act, and it was also found out that they tend to engage in risky sexual practices with their regular non-paying partner without condom, thinking that it was not necessary. Key words: HIV, female sex workers, knowledge, risk behaviour, condom use, India, Mumbai, brothels.
印度马哈拉施特拉邦的女性性工作者(FSW)中艾滋病毒感染率最高(7.4%)。马哈拉施特拉邦(Maharashtra)的首府孟买拥有以妓院为主的大型性产业,在过去十年中,该邦艾滋病感染率的总体平均下降速度落后于其他地区。通过孟买地区艾滋病控制协会(MDACS)和许多非政府组织(ngo)的积极作用,性工作者现在广泛使用避孕套,但许多相关的危险行为仍然存在,并导致孟买的性工作者中艾滋病毒的高感染率。本研究是基于社区的描述性研究,旨在评估2015年孟买FSW人群中HIV/ aids相关知识和性风险行为。知识评估采用“累积知识评分”,通过18个问题来评估艾滋病毒/艾滋病知识。此外,亦分别评估有偶然性客户、固定男性客户、固定非付费男性伴侣及非固定非付费客户的女服务员的性行为。91名在孟买妓院工作的女服务员表示知情同意,并被有意选择参加这项研究。受访者的平均年龄为32.9岁,四分之三的人是文盲,62%的人已婚或有同居伴侣。85%的研究人群报告在艾滋病毒/艾滋病累积知识方面得分高于平均水平(得分≥8),并且与定期和偶尔的客户都使用了近100%的安全套。该研究揭示了FSW及其定期非付费合作伙伴中需要紧急解决的一些风险因素。大多数FSW(86%)在性行为中使用不止一个避孕套,而且还发现他们倾向于不带避孕套与经常不付钱的伴侣进行危险的性行为,认为没有必要。关键词:艾滋病,女性性工作者,知识,危险行为,安全套使用,印度,孟买,妓院。
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引用次数: 3
Evaluation of the frequency of use of herbal drugs with concomitant administration of highly active antiretroviral therapy and its effect on medication adherence in two health care facilities in south western Nigeria 评估在尼日利亚西南部的两家卫生保健机构中使用草药并同时给予高活性抗逆转录病毒治疗的频率及其对服药依从性的影响
Pub Date : 2017-01-31 DOI: 10.5897/JAHR2016.0399
Ilomuanya Margaret, Okubanjo Omotunde, Azubuike Chukwuemeka, Oguntibeju, Adeyemi, A. Dolapo, M. Chima
The aim of this study was to evaluate the prevalence of the concomitant use of herbal medicine and anti-retroviral drugs in people living with HIV/AIDs and to evaluate the reasons given by the patients for concomitant administration of highly active antiretroviral therapy (HAART) with herbal drugs in order to establish a possible link between the use of herbal medicines and adherence. A cross sectional study design was utilized via systematic sampling for recruitment of HIV positive individuals receiving their medications in Amuwo-Odofin and Ojo areas in Lagos, Nigeria. Based on the inclusion criteria, 351 HIV positive patients were recruited into the study from the HIV outpatient clinics of two hospitals and had the questionnaires administered to them. 42.7% of the respondents stated that they use herbal medicines. The association for each of the herbal medicines with side effects experienced with the use of ARVs was statistically significant upon cross-tabulation and was a major predictor of herbal drug use. The prevalence of herbal drug use in patients who were adhering to HAART medication was not significantly different from those who were not adhering to medication (p = 0.75 and χ2 = 6.902). The use or lack of use of herbal medicine is not a determinant for adherence. The most profound reason for herb use was to improve treatment. However, herb/drug interaction studies are imperative to ascertain if interactions occurring are beneficial or harmful. The pharmacist must counsel and re-counsel patients on HAART, not to use herbal products with their antiretroviral medications to avoid drug-herb interactions which could be potentially life threatening. Key words: Highly active antiretroviral therapy (HAART), herbal drugs, adherence.
本研究的目的是评估艾滋病毒/艾滋病患者同时使用草药和抗逆转录病毒药物的流行率,并评估患者同时使用高效抗逆转录病毒疗法(HAART)和草药的原因,以确定草药的使用和依从性之间的可能联系。在尼日利亚拉各斯的Amuwo-Odofin和Ojo地区,通过系统抽样招募接受药物治疗的HIV阳性个体,采用横断面研究设计。根据纳入标准,从两家医院的HIV门诊招募了351名HIV阳性患者参与研究,并对他们进行了问卷调查。42.7%的受访者表示他们使用草药。每种草药与抗逆转录病毒药物使用副作用的相关性在交叉列表中具有统计学意义,是草药使用的主要预测因素。坚持接受HAART治疗的患者和不坚持接受药物治疗的患者的草药使用率没有显著差异(p=0.75,χ2=6.902)。草药的使用或不使用不是坚持的决定因素。使用草药最深刻的原因是为了改善治疗。然而,必须进行草药/药物相互作用研究,以确定发生的相互作用是有益的还是有害的。药剂师必须就HAART向患者提供咨询和再咨询,不要将草药产品与抗逆转录病毒药物一起使用,以避免可能危及生命的药物与草药相互作用。关键词:高效抗逆转录病毒疗法(HAART),草药,坚持。
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引用次数: 11
期刊
Journal of AIDS and HIV research (Online)
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