Pub Date : 2024-05-27DOI: 10.1088/2043-6262/ad4bae
Samer Y Al-Qaraleh, Wael A Al-Zereini, Sawsan A Oran, Osama Y Al-Madanat, Aiman I Al-Qtaitat and Abdalrahim Alahmad
Breast cancer is a disease associated with high morbidity and mortality rates worldwide. The potential use of biogenic nanoparticles as alternative anticancer agents has been immensely acknowledged in several studies, particularly selenium nanoparticles (SeNPs). Nanoparticles were synthesised using the aqueous extract of Moringa peregrine (MPM-SeNPs) and were PEGylated (PEG-MPM-SeNPs). MPM-SeNPs were characterised by chemical and physical techniques. The successful capping of MPM-SeNPs with PEG was confirmed by spectrophotometric measurements and via Fourier-transform infrared spectroscopy (FT-IR) analysis. Furthermore, the effect of PEGylation of MPM-SeNPs on enhancing their anti-breast cancer activity and as a drug delivery agent was evaluated. Therefore, the loading efficiency and release of DOX at different pH values were measured; the antiproliferative activity of PEG-MPM-SeNPs against the adenocarcinoma breast cancer cell line (MDA-MB-231) was evaluated and compared with that of biogenic MPM-SeNPs and DOX-conjugated PEG-MPM-SeNPs. PEG-MPM-SeNPs and DOX-PEG-MPM-SeNPs had reduced IC50 values compared to MPM-SeNPs; IC50 of 11.54 ± 1.74 and 31.27 ± 2.9 μg mL−1 compared to 71.4 ± 3.4 μg mL−1, respectively. MPM-SeNPs and PEG-MPM-SeNPs caused apoptosis to MDA-MB-231 cells with a significant decrease in the mitochondrial membrane potential (MMP), increase in the released cytochrome C (Cyt C), and activation of caspase-3/9 (P < 0.05). Linking DOX to PEG-MPM-SeNPs led to an increase in caspase-3/8 concentrations and an increase in the released Cyt C, but there were non-significant differences in MMP (P > 0.1) between treated and untreated control cancer cells. MPM-SeNPs and PEG-MPM-SeNPs caused apoptotic reactions via an intrinsic pathway, while linking DOX to PEG-MPM-SeNPs caused apoptosis in cancer cells through an extrinsic pathway.
{"title":"Enhanced anti-breast cancer activity of green synthesized selenium nanoparticles by PEGylation: induction of apoptosis and potential anticancer drug delivery system","authors":"Samer Y Al-Qaraleh, Wael A Al-Zereini, Sawsan A Oran, Osama Y Al-Madanat, Aiman I Al-Qtaitat and Abdalrahim Alahmad","doi":"10.1088/2043-6262/ad4bae","DOIUrl":"https://doi.org/10.1088/2043-6262/ad4bae","url":null,"abstract":"Breast cancer is a disease associated with high morbidity and mortality rates worldwide. The potential use of biogenic nanoparticles as alternative anticancer agents has been immensely acknowledged in several studies, particularly selenium nanoparticles (SeNPs). Nanoparticles were synthesised using the aqueous extract of Moringa peregrine (MPM-SeNPs) and were PEGylated (PEG-MPM-SeNPs). MPM-SeNPs were characterised by chemical and physical techniques. The successful capping of MPM-SeNPs with PEG was confirmed by spectrophotometric measurements and via Fourier-transform infrared spectroscopy (FT-IR) analysis. Furthermore, the effect of PEGylation of MPM-SeNPs on enhancing their anti-breast cancer activity and as a drug delivery agent was evaluated. Therefore, the loading efficiency and release of DOX at different pH values were measured; the antiproliferative activity of PEG-MPM-SeNPs against the adenocarcinoma breast cancer cell line (MDA-MB-231) was evaluated and compared with that of biogenic MPM-SeNPs and DOX-conjugated PEG-MPM-SeNPs. PEG-MPM-SeNPs and DOX-PEG-MPM-SeNPs had reduced IC50 values compared to MPM-SeNPs; IC50 of 11.54 ± 1.74 and 31.27 ± 2.9 μg mL−1 compared to 71.4 ± 3.4 μg mL−1, respectively. MPM-SeNPs and PEG-MPM-SeNPs caused apoptosis to MDA-MB-231 cells with a significant decrease in the mitochondrial membrane potential (MMP), increase in the released cytochrome C (Cyt C), and activation of caspase-3/9 (P < 0.05). Linking DOX to PEG-MPM-SeNPs led to an increase in caspase-3/8 concentrations and an increase in the released Cyt C, but there were non-significant differences in MMP (P > 0.1) between treated and untreated control cancer cells. MPM-SeNPs and PEG-MPM-SeNPs caused apoptotic reactions via an intrinsic pathway, while linking DOX to PEG-MPM-SeNPs caused apoptosis in cancer cells through an extrinsic pathway.","PeriodicalId":7359,"journal":{"name":"Advances in Natural Sciences: Nanoscience and Nanotechnology","volume":"45 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141166455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-06DOI: 10.1088/2043-6262/ad22d6
Adithya Lenin Tamilkovan, Pandurangan Arumugam
BNNTs are the tubular variants of the ceramic compound hexagonal boron nitride (hBN) and are known for their high thermal and chemical stability. The research on BNNTs is ever-evolving, researchers are on a quest to optimise the synthesis procedure for the nanomaterial. Here a variety of currently followed synthesis techniques were discussed and compared. X-ray diffraction patterns and electron microscopy results of BNNTs synthesised by various techniques were compared, this would give the pros and cons of each synthesis technique. Based on this, suggestions for the best-suited synthesis technique from an academic as well as industrial perspective were given. The individual properties of these nanotubes, along with their potential applications in the field of spintronics, surface wetting, and radiation capture were delineated.
BNNTs 是陶瓷化合物六方氮化硼(hBN)的管状变体,以其高度的热稳定性和化学稳定性而著称。有关 BNNTs 的研究一直在不断发展,研究人员一直在努力优化这种纳米材料的合成过程。在此,我们对目前采用的各种合成技术进行了讨论和比较。通过比较各种技术合成的 BNNT 的 X 射线衍射图样和电子显微镜结果,可以看出每种合成技术的优缺点。在此基础上,从学术和工业角度对最适合的合成技术提出了建议。此外,还介绍了这些纳米管的特性,以及它们在自旋电子学、表面润湿和辐射捕获领域的潜在应用。
{"title":"A current review on boron nitride nanotubes and their applications","authors":"Adithya Lenin Tamilkovan, Pandurangan Arumugam","doi":"10.1088/2043-6262/ad22d6","DOIUrl":"https://doi.org/10.1088/2043-6262/ad22d6","url":null,"abstract":"BNNTs are the tubular variants of the ceramic compound hexagonal boron nitride (hBN) and are known for their high thermal and chemical stability. The research on BNNTs is ever-evolving, researchers are on a quest to optimise the synthesis procedure for the nanomaterial. Here a variety of currently followed synthesis techniques were discussed and compared. X-ray diffraction patterns and electron microscopy results of BNNTs synthesised by various techniques were compared, this would give the pros and cons of each synthesis technique. Based on this, suggestions for the best-suited synthesis technique from an academic as well as industrial perspective were given. The individual properties of these nanotubes, along with their potential applications in the field of spintronics, surface wetting, and radiation capture were delineated.","PeriodicalId":7359,"journal":{"name":"Advances in Natural Sciences: Nanoscience and Nanotechnology","volume":"18 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139764742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-02DOI: 10.1088/2043-6262/ad21e8
Sourav Ghosh, K Martin Sagayam, Dibyajyoti Haldar, A Amir Anton Jone, Biswaranjan Acharya, Vassilis C Gerogiannis, Andreas Kanavos
Biosensors have gained significant attention in various fields such as food processing, agriculture, environmental monitoring, and healthcare. With the continuous advancements in research and technology, a wide variety of biosensors are being developed to cater to diverse applications. However, the effective development of nanobiosensors, particularly the synthesis of nanomaterials, remains a crucial step. Many nanobiosensors face challenges related to instability and selectivity, making it difficult to achieve proper packaging. While some biosensors have been successfully implemented in commercial settings, there is a pressing need to address their limitations and advance their capabilities. The next generation of biosensors, based on nanomaterials, holds promise in overcoming these challenges and enhancing the overall performance of biosensor devices. The commercial viability of these biosensors will rely on their accuracy, reliability, and cost-effectiveness. This review paper provides an overview of various types of nanomaterials and their applications in the development of nanobiosensors. The paper highlights a comparison of different nanomaterial-based biosensors, discussing their advantages, limitations, and performance characteristics.
{"title":"A review on the types of nanomaterials and methodologies used for the development of biosensors","authors":"Sourav Ghosh, K Martin Sagayam, Dibyajyoti Haldar, A Amir Anton Jone, Biswaranjan Acharya, Vassilis C Gerogiannis, Andreas Kanavos","doi":"10.1088/2043-6262/ad21e8","DOIUrl":"https://doi.org/10.1088/2043-6262/ad21e8","url":null,"abstract":"Biosensors have gained significant attention in various fields such as food processing, agriculture, environmental monitoring, and healthcare. With the continuous advancements in research and technology, a wide variety of biosensors are being developed to cater to diverse applications. However, the effective development of nanobiosensors, particularly the synthesis of nanomaterials, remains a crucial step. Many nanobiosensors face challenges related to instability and selectivity, making it difficult to achieve proper packaging. While some biosensors have been successfully implemented in commercial settings, there is a pressing need to address their limitations and advance their capabilities. The next generation of biosensors, based on nanomaterials, holds promise in overcoming these challenges and enhancing the overall performance of biosensor devices. The commercial viability of these biosensors will rely on their accuracy, reliability, and cost-effectiveness. This review paper provides an overview of various types of nanomaterials and their applications in the development of nanobiosensors. The paper highlights a comparison of different nanomaterial-based biosensors, discussing their advantages, limitations, and performance characteristics.","PeriodicalId":7359,"journal":{"name":"Advances in Natural Sciences: Nanoscience and Nanotechnology","volume":"14 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139764897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-19DOI: 10.1088/2043-6262/ad1a9b
M S Anandha Prabhu, G Edwin Sheela, Abeer M Mohammad, Rabab A Hegazy, S Sasi Florence, V Sarojini
In this study, we explored the green synthesis of metal nanoparticles (Ag-NPs, Au-NPs, and Pd-NPs) using Moringa oleifera seed (MOS) extract, which is known for its nutrient density, antioxidant properties, anti-inflammatory effects, and potential benefits in managing cholesterol, blood sugar levels, as well as promoting digestion, skin, and hair health. The nanoparticles’ size was controlled by varying the concentration of MOS extract. The successful formation of Au-NPs and Ag-NPs was confirmed through surface plasmon resonance (SPR), while the absence of absorption at 420 nm indicated the reduction of Pd2+ ions to Pd0, affirming the synthesis of Pd-NPs. The nanoparticles exhibited mono-dispersed, spherical shapes with confirmed crystallinity. Sizes were determined as 28 nm for Pd-NPs, 5 nm for Au-NPs, and 19 nm for Ag-NPs. The MOS extract’s phenols and proteins played a crucial role in reducing and stabilising Ag-NPs, Au-NPs, and Pd-NPs. Notably, the synthesised nanoparticles demonstrated strong antimicrobial activity, particularly against Salmonella typhi, making them potential antibacterial agents. The catalytic efficiency of Au-NPs, Ag-NPs and Pd-NPs was studied using the reduction of 4-Nitrophenol (4-NP) by NaBH4 to 4-Aminophenol. Additionally, Au-NPs showed enhanced photocatalytic degradation rate constant and catalytic reaction rate constant of 0.0038/min and 0.261/min respectively, due to their small size and increased surface area. By combining a green synthesis approach with an in-depth analysis of properties and diverse applications, this study provides valuable insights into the immense potential of MOS-assisted metal nanoparticles for various technological and environmental advancements.
{"title":"Biogenic synthesis of silver, gold, and palladium nanoparticles using moringa oleifera seeds: exploring photocatalytic, catalytic, and antimicrobial activities","authors":"M S Anandha Prabhu, G Edwin Sheela, Abeer M Mohammad, Rabab A Hegazy, S Sasi Florence, V Sarojini","doi":"10.1088/2043-6262/ad1a9b","DOIUrl":"https://doi.org/10.1088/2043-6262/ad1a9b","url":null,"abstract":"In this study, we explored the green synthesis of metal nanoparticles (Ag-NPs, Au-NPs, and Pd-NPs) using <italic toggle=\"yes\">Moringa oleifera</italic> seed (MOS) extract, which is known for its nutrient density, antioxidant properties, anti-inflammatory effects, and potential benefits in managing cholesterol, blood sugar levels, as well as promoting digestion, skin, and hair health. The nanoparticles’ size was controlled by varying the concentration of MOS extract. The successful formation of Au-NPs and Ag-NPs was confirmed through surface plasmon resonance (SPR), while the absence of absorption at 420 nm indicated the reduction of Pd<sup>2+</sup> ions to Pd<sup>0</sup>, affirming the synthesis of Pd-NPs. The nanoparticles exhibited mono-dispersed, spherical shapes with confirmed crystallinity. Sizes were determined as 28 nm for Pd-NPs, 5 nm for Au-NPs, and 19 nm for Ag-NPs. The MOS extract’s phenols and proteins played a crucial role in reducing and stabilising Ag-NPs, Au-NPs, and Pd-NPs. Notably, the synthesised nanoparticles demonstrated strong antimicrobial activity, particularly against <italic toggle=\"yes\">Salmonella typhi</italic>, making them potential antibacterial agents. The catalytic efficiency of Au-NPs, Ag-NPs and Pd-NPs was studied using the reduction of 4-Nitrophenol (4-NP) by NaBH<sub>4 </sub>to 4-Aminophenol. Additionally, Au-NPs showed enhanced photocatalytic degradation rate constant and catalytic reaction rate constant of 0.0038/min and 0.261/min respectively, due to their small size and increased surface area. By combining a green synthesis approach with an in-depth analysis of properties and diverse applications, this study provides valuable insights into the immense potential of MOS-assisted metal nanoparticles for various technological and environmental advancements.","PeriodicalId":7359,"journal":{"name":"Advances in Natural Sciences: Nanoscience and Nanotechnology","volume":"35 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139508552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Various materials and technologies are being employed to address the concern of increased wastewater generation. In this work, the synthesis of ZSM-5 (Zeolite Socony Mobil-5) and graphene (GR) composite, their characterisation, and application for the removal of dyes are presented. Two composites of ZSM-5 and GR composites were prepared via the hydrothermal method by varying the loading amount of GR, i.e. 1% and 5%, and labelled as GZ1 and GZ5. The parent and composite materials were characterised using field emission scanning electron microscope (FE-SEM), x-ray diffraction (XRD), diffuse reflectance spectroscopy (DRS), x-ray photoelectrons spectroscopy (XPS), Raman, and Fourier transform infrared (FTIR). The materials were then employed for the photodegradation of methyl orange (MO) dye. The adsorption efficiencies for ZSM-5, GR, GZ1, and GZ5 were found as 0%, 17.8%, 0%, and 16% respectively. According to photodegradation results, the GZ1 composite exhibits the maximum degradation efficiency of 75.3% for 20 ppm of MO, within 180 min of light exposure. The scavenger studies were performed to evaluate the role of active oxygen species (AOS) in the photocatalysis mechanism. All studies were performed with the catalyst dosage of 0.5 mg ml−1. The degradation efficiencies for GR, GZ5, and Z5 were reported as 34.2%, 20.8%, and 17.5%, respectively. On increasing the irradiation time to 240 min, the degradation efficiency of GZ1 reached 92%. The removal efficiencies for MO (7 ppm) and methyl blue (5 ppm) in a 12-ppm dye mixture were observed to be 98% and 97.2% respectively within 180 min of light exposure with GZ1 composite.
{"title":"Synthesis and application of ZSM-5/Graphene composite for photocatalytic degradation of industrial dyes","authors":"Veena Sodha, Mahuya Bandyopadhyay, Rama Gaur, Rajib Bandyopadhyay, Syed Shahabuddin","doi":"10.1088/2043-6262/ad1a9e","DOIUrl":"https://doi.org/10.1088/2043-6262/ad1a9e","url":null,"abstract":"Various materials and technologies are being employed to address the concern of increased wastewater generation. In this work, the synthesis of ZSM-5 (Zeolite Socony Mobil-5) and graphene (GR) composite, their characterisation, and application for the removal of dyes are presented. Two composites of ZSM-5 and GR composites were prepared via the hydrothermal method by varying the loading amount of GR, i.e. 1% and 5%, and labelled as GZ1 and GZ5. The parent and composite materials were characterised using field emission scanning electron microscope (FE-SEM), x-ray diffraction (XRD), diffuse reflectance spectroscopy (DRS), x-ray photoelectrons spectroscopy (XPS), Raman, and Fourier transform infrared (FTIR). The materials were then employed for the photodegradation of methyl orange (MO) dye. The adsorption efficiencies for ZSM-5, GR, GZ1, and GZ5 were found as 0%, 17.8%, 0%, and 16% respectively. According to photodegradation results, the GZ1 composite exhibits the maximum degradation efficiency of 75.3% for 20 ppm of MO, within 180 min of light exposure. The scavenger studies were performed to evaluate the role of active oxygen species (AOS) in the photocatalysis mechanism. All studies were performed with the catalyst dosage of 0.5 mg ml<sup>−1</sup>. The degradation efficiencies for GR, GZ5, and Z5 were reported as 34.2%, 20.8%, and 17.5%, respectively. On increasing the irradiation time to 240 min, the degradation efficiency of GZ1 reached 92%. The removal efficiencies for MO (7 ppm) and methyl blue (5 ppm) in a 12-ppm dye mixture were observed to be 98% and 97.2% respectively within 180 min of light exposure with GZ1 composite.","PeriodicalId":7359,"journal":{"name":"Advances in Natural Sciences: Nanoscience and Nanotechnology","volume":"103 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139508268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-17DOI: 10.1088/2043-6262/ad1a9d
P Raghavendra, Y Chandra Sekhar, G Vishwakshan Reddy, P Sri Chandana, L Subramanyam Sarma
The core-shell structured Pt@Aubimetallic nanoparticles (NPs) were decorated on the reduced graphene oxide (RGO) surface by a heteroepitaxial growth method. The morphological details of Pt@Au/RGO core/shell bimetallic NPs were assessed by high-resolution transmission electron microscopy (HR-TEM), x-ray diffraction (XRD), and energy-dispersive x-ray spectroscopy (EDS). Electron microscopy results revealed that Pt@Au particles of 3.4 nm were firmly attached to RGO sheets. The electrochemical response of Pt@Au/RGO nanostructured electrocatalyst was measured through cyclic voltammetry (CV) at room temperature in 0.1 M KOH solution. Oxygen reduction reaction (ORR) efficacies of Pt@Au/RGO were evaluated by linear sweep voltammetry (LSV) by rotating catalyst-coated glassy carbon (GC) electrode at different rotation speeds in oxygen saturated 0.1 M KOH solution. The electrochemical activity descriptors (half-wave potential, onset potential, limiting current density) were assessed from ORR polarisation curves. The results revealed that Pt@Au/RGO bimetallic NPs showed enhanced higher catalytic activity towards ORR compared to commercial Pt/C catalyst as well as similarly synthesised Pt/RGO and Au/RGO. The enhanced catalytic activity of Pt@Au/RGO electrocatalyst might result from the core/shell structure with a tiny Pt core and a thin Au shell, as well as the synergistic effects of Au and Pt.
{"title":"Hetero-epitaxial grown Pt@Au core-shell bimetallic nanoparticles on reduced graphene oxide (RGO) as electrocatalyst for oxygen reduction reaction in alkaline media","authors":"P Raghavendra, Y Chandra Sekhar, G Vishwakshan Reddy, P Sri Chandana, L Subramanyam Sarma","doi":"10.1088/2043-6262/ad1a9d","DOIUrl":"https://doi.org/10.1088/2043-6262/ad1a9d","url":null,"abstract":"The core-shell structured Pt@Aubimetallic nanoparticles (NPs) were decorated on the reduced graphene oxide (RGO) surface by a heteroepitaxial growth method. The morphological details of Pt@Au/RGO core/shell bimetallic NPs were assessed by high-resolution transmission electron microscopy (HR-TEM), x-ray diffraction (XRD), and energy-dispersive x-ray spectroscopy (EDS). Electron microscopy results revealed that Pt@Au particles of 3.4 nm were firmly attached to RGO sheets. The electrochemical response of Pt@Au/RGO nanostructured electrocatalyst was measured through cyclic voltammetry (CV) at room temperature in 0.1 M KOH solution. Oxygen reduction reaction (ORR) efficacies of Pt@Au/RGO were evaluated by linear sweep voltammetry (LSV) by rotating catalyst-coated glassy carbon (GC) electrode at different rotation speeds in oxygen saturated 0.1 M KOH solution. The electrochemical activity descriptors (half-wave potential, onset potential, limiting current density) were assessed from ORR polarisation curves. The results revealed that Pt@Au/RGO bimetallic NPs showed enhanced higher catalytic activity towards ORR compared to commercial Pt/C catalyst as well as similarly synthesised Pt/RGO and Au/RGO. The enhanced catalytic activity of Pt@Au/RGO electrocatalyst might result from the core/shell structure with a tiny Pt core and a thin Au shell, as well as the synergistic effects of Au and Pt.","PeriodicalId":7359,"journal":{"name":"Advances in Natural Sciences: Nanoscience and Nanotechnology","volume":"10 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139508267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-17DOI: 10.1088/2043-6262/ad1aa0
Duc Minh Trinh Dinh, Anh Van Thi Le, Phuong Hong Lam, Mai Thi Le, Dung My Thi Dang, Chien Mau Dang, Ngan Nguyen Le
Enrofloxacin has been widely and increasingly used in veterinary medicine to treat infection on animals which could lead to antibiotic resistance for the consumer. Among the available detection techniques for Enrofloxacin, immunoassay lateral flow test strip is realised to be a rapid and accurate detection method for on-site analysis of Enrofloxacin antibiotic. The current study aims to analyse the application of inkjet printing technology on the immobilisation of biological substances at the test line and control line position of the test strip. With the printing parameters value at 35 °C, 35 °C, 7 layers and 15 μm for cartridge temperature, substrate temperature, printing layers and drop spacing, respectively, the fabricated test strips show correlation coefficient R