Pub Date : 2015-09-11DOI: 10.4172/2167-0897.1000194
Nobuko Shiono, Kohta Takei, Takahiro Yamada, T. Tachibana, Kazutoshi Cho, H. Minakami
Double aortic arch (DAA) is a form of vascular ring found in approximately 1 in 2000–4000 pregnancies on fetal echocardiography. In some cases of DAA, respiratory compromise occurs during infancy due to compression of the trachea, which is completely encircled by the right aortic arch (RAA) and left aortic arch (LAA). RAA and left arterial duct were initially seen on screening fetal echocardiography in a 36-year-old Japanese woman at gestational week (GW) 23. The fetus was later found to have DAA by detailed echocardiography at GW 26. The female neonate born at GW 38 weighing 2894 g with 1- and 5-minute Apgar scores of 8 and 9, respectively, developed tachypnea, stridor, and wheezing soon after birth, and underwent successful surgical correction 10 hours after birth. Thus, prenatal diagnosis of DAA aided in early recovery in this case.
{"title":"A Case of Prenatal Presentation with Double Aortic Arch","authors":"Nobuko Shiono, Kohta Takei, Takahiro Yamada, T. Tachibana, Kazutoshi Cho, H. Minakami","doi":"10.4172/2167-0897.1000194","DOIUrl":"https://doi.org/10.4172/2167-0897.1000194","url":null,"abstract":"Double aortic arch (DAA) is a form of vascular ring found in approximately 1 in 2000–4000 pregnancies on fetal echocardiography. In some cases of DAA, respiratory compromise occurs during infancy due to compression of the trachea, which is completely encircled by the right aortic arch (RAA) and left aortic arch (LAA). RAA and left arterial duct were initially seen on screening fetal echocardiography in a 36-year-old Japanese woman at gestational week (GW) 23. The fetus was later found to have DAA by detailed echocardiography at GW 26. The female neonate born at GW 38 weighing 2894 g with 1- and 5-minute Apgar scores of 8 and 9, respectively, developed tachypnea, stridor, and wheezing soon after birth, and underwent successful surgical correction 10 hours after birth. Thus, prenatal diagnosis of DAA aided in early recovery in this case.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2015-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0897.1000194","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-09-11DOI: 10.4172/2167-0897.1000195
Sunil Munakomi
There is presence of falcine sinus leading to the characteristic accessory torcula appearance in the cerebral venous imaging studies. This differentiates it from the vein of Galen aneurysmal dilatation wherein there is presence of a normal draining straight sinus. There may be associated other venous anomalies like the stenosed, fenestrated, duplicated or absent straight sinus owing to the absence of cavernous sinus drainage prior to six months of age [3].
{"title":"Vein of Galen Aneurysmal Malformation","authors":"Sunil Munakomi","doi":"10.4172/2167-0897.1000195","DOIUrl":"https://doi.org/10.4172/2167-0897.1000195","url":null,"abstract":"There is presence of falcine sinus leading to the characteristic accessory torcula appearance in the cerebral venous imaging studies. This differentiates it from the vein of Galen aneurysmal dilatation wherein there is presence of a normal draining straight sinus. There may be associated other venous anomalies like the stenosed, fenestrated, duplicated or absent straight sinus owing to the absence of cavernous sinus drainage prior to six months of age [3].","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2015-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0897.1000195","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-09-05DOI: 10.4172/2167-0897.1000189
Ekwochi Uchenna, A. Nwabueze, N. Kingsley
Twin-twin transfusion syndrome (TTTS) is one of the most serious complications of monochorionic multiple gestations in which the receipient twin becomes plethoric while the donor twin becomes anaemic. We report the case of the 1st of a set of male twins who presented on the 2nd day of life with excessive ruddiness of the whole body noted at birth and yellowness of the eyes and face noted on the 2nd day of life. Given the comparative clinicolaboratory findings, a diagnosis of neonatal polycythemia secondary to twin to twin transfusion syndrome was made. Post partial exchange blood transfusion (PET) recovery was remarkable. This report was made because of its rarity and to raise the index of suspicion for such cases to enable proper evaluation and management.
{"title":"Neonatal Polycythemia Secondary to Twin to Twin Transfusion Syndrome- A Case Report","authors":"Ekwochi Uchenna, A. Nwabueze, N. Kingsley","doi":"10.4172/2167-0897.1000189","DOIUrl":"https://doi.org/10.4172/2167-0897.1000189","url":null,"abstract":"Twin-twin transfusion syndrome (TTTS) is one of the most serious complications of monochorionic multiple gestations in which the receipient twin becomes plethoric while the donor twin becomes anaemic. We report the case of the 1st of a set of male twins who presented on the 2nd day of life with excessive ruddiness of the whole body noted at birth and yellowness of the eyes and face noted on the 2nd day of life. Given the comparative clinicolaboratory findings, a diagnosis of neonatal polycythemia secondary to twin to twin transfusion syndrome was made. Post partial exchange blood transfusion (PET) recovery was remarkable. This report was made because of its rarity and to raise the index of suspicion for such cases to enable proper evaluation and management.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"129 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2015-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0897.1000189","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-09-05DOI: 10.4172/2167-0897.1000190
I. Ndu, Bo Edelu, S. Uwaezuoke, Josephat Chinawa, A. Ubesie, C. C. Ogoke, K. Iloh, U. Ekwochi
Background: Low birth weight (LBW) deliveries contribute to high neonatal mortality rates (NMR) in developing countries. Several maternal risk factors are associated with LBW newborns. Appropriate interventions will help to reduce the incidence of LBW deliveries in these countries and improve neonatal survival outcomes. This study aims to identify maternal risk factors associated with LBW in Enugu, South-east Nigeria. Subjects and Methods: A multi-centre, cross-sectional study of 506 consecutive live newborns delivered between September 1st and December 31st 2011 was conducted in a south-east Nigerian city. Maternal data included last menstrual period, history of illnesses such as hypertensive disorders and anaemia during pregnancy, delivery date and time. The weights of the newborns were measured at birth. Data were analyzed with the Statistical Package for Social Sciences (SPSS) version 18.0. The relative risk of having a LBW newborn with maternal factors was calculated. Results: There were a total of 72 LBW newborns, giving an incidence rate of 14.2%. Eighteen (25%) of the mothers with LBW deliveries had malaria in pregnancy while 4 (5.6%) tested positive for human immuno-deficiency virus (HIV). The relative risk of having a LBW newborn was high in maternal HIV (RR=3.25, C.I=1.51-6.97), hypertension in pregnancy (RR=3.07, C.I=1.52-6.22), ante partum hemorrhage (APH) (RR=7.20, C.I=5.79-8.95), as well as primiparity (RR=1.35, C.I=0.88-2.08). Conclusion: Common maternal risk factors for LBW babies in Enugu, south-east Nigeria include APH, HIV, hypertension in pregnancy, and primiparity.
{"title":"Maternal Risk Factors Associated with Low Birth Weight Neonates: A Multi-Centre, Cross-Sectional Study in a Developing Country","authors":"I. Ndu, Bo Edelu, S. Uwaezuoke, Josephat Chinawa, A. Ubesie, C. C. Ogoke, K. Iloh, U. Ekwochi","doi":"10.4172/2167-0897.1000190","DOIUrl":"https://doi.org/10.4172/2167-0897.1000190","url":null,"abstract":"Background: Low birth weight (LBW) deliveries contribute to high neonatal mortality rates (NMR) in developing countries. Several maternal risk factors are associated with LBW newborns. Appropriate interventions will help to reduce the incidence of LBW deliveries in these countries and improve neonatal survival outcomes. This study aims to identify maternal risk factors associated with LBW in Enugu, South-east Nigeria. Subjects and Methods: A multi-centre, cross-sectional study of 506 consecutive live newborns delivered between September 1st and December 31st 2011 was conducted in a south-east Nigerian city. Maternal data included last menstrual period, history of illnesses such as hypertensive disorders and anaemia during pregnancy, delivery date and time. The weights of the newborns were measured at birth. Data were analyzed with the Statistical Package for Social Sciences (SPSS) version 18.0. The relative risk of having a LBW newborn with maternal factors was calculated. Results: There were a total of 72 LBW newborns, giving an incidence rate of 14.2%. Eighteen (25%) of the mothers with LBW deliveries had malaria in pregnancy while 4 (5.6%) tested positive for human immuno-deficiency virus (HIV). The relative risk of having a LBW newborn was high in maternal HIV (RR=3.25, C.I=1.51-6.97), hypertension in pregnancy (RR=3.07, C.I=1.52-6.22), ante partum hemorrhage (APH) (RR=7.20, C.I=5.79-8.95), as well as primiparity (RR=1.35, C.I=0.88-2.08). Conclusion: Common maternal risk factors for LBW babies in Enugu, south-east Nigeria include APH, HIV, hypertension in pregnancy, and primiparity.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"18 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2015-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-09-04DOI: 10.4172/2167-0897.1000191
P. Kotiya, Xueping Zhu
Background: Parenteral Nutrition (PN) provided to the Very Low Birth Weighti¼VLBWi¼premature infants should be resulted in gradually development as of the other fetuses following the same gestational age. Even after providing the proven beneficial parenteral nutrition supplements, VLBW infants are often presents with the unfavorable results; the main reason behind it is the decision of the administration of parenteral nutrition, whether it is in early life or later days. Objective: The objective of this study is to explore the effect of early and late parenteral nutrition in the VLBW premature infants. In this study we hypothesize that early parenteral nutrition is associated with comparatively beneficial outcomes. Methods: The PubMed (PubMed Central), Medline, and Google Scholar databases were searched from 1993 to 2013. Methodological quality assessment was based on the PRISMA guidelines. Data analysis were conducted with RevMan 5.3 Results: Ten studies including thirteen trials met our inclusion criteria. The aggregate results of trials showed that early parenteral nutrition was well tolerated by VLBW preterm infants and there was significant reduction in sepsis (RR=0.82, 95% CI=0.69~0.98, P=0.03) Conclusion: Comparison made between the patients provided early and late parenteral nutrition, the development and reduction of clinical disease were significantly lower in the early parenteral nutrition group. The cost-effectiveness of these preparations, however, needs to be further explored. The poor qualities of studies call into a question and robustness of the analysis.
{"title":"Effects of Early and Late Parenteral Nutrition on Clinical Outcomes in Very Low Birth Weight Preterm Infants: A Systematic Review and Meta-analysis","authors":"P. Kotiya, Xueping Zhu","doi":"10.4172/2167-0897.1000191","DOIUrl":"https://doi.org/10.4172/2167-0897.1000191","url":null,"abstract":"Background: Parenteral Nutrition (PN) provided to the Very Low Birth Weighti¼VLBWi¼premature infants should be resulted in gradually development as of the other fetuses following the same gestational age. Even after providing the proven beneficial parenteral nutrition supplements, VLBW infants are often presents with the unfavorable results; the main reason behind it is the decision of the administration of parenteral nutrition, whether it is in early life or later days. \u0000Objective: The objective of this study is to explore the effect of early and late parenteral nutrition in the VLBW premature infants. In this study we hypothesize that early parenteral nutrition is associated with comparatively beneficial outcomes. \u0000Methods: The PubMed (PubMed Central), Medline, and Google Scholar databases were searched from 1993 to 2013. Methodological quality assessment was based on the PRISMA guidelines. Data analysis were conducted with RevMan 5.3 \u0000Results: Ten studies including thirteen trials met our inclusion criteria. The aggregate results of trials showed that early parenteral nutrition was well tolerated by VLBW preterm infants and there was significant reduction in sepsis (RR=0.82, 95% CI=0.69~0.98, P=0.03) \u0000Conclusion: Comparison made between the patients provided early and late parenteral nutrition, the development and reduction of clinical disease were significantly lower in the early parenteral nutrition group. The cost-effectiveness of these preparations, however, needs to be further explored. The poor qualities of studies call into a question and robustness of the analysis.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2015-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0897.1000191","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-26DOI: 10.4172/2167-0897.1000188
Y. Imaizumi, K. Hayakawa
Objective: We aimed to determine the perinatal mortality rates (PMRs) for monozygotic (MZ) twins, dizygotic (DZ) twins, and singletons, together with the associated risk factors for these PMRs. Study design: PMRs of zygotic twins and singletons were estimated using Japanese vital statistics from 1995 to 2008. Results: Declines were seen in fetal death rates [FDRs; defined as deaths after a gestational age of (GA) 22 weeks], early neonatal death rates (ENDRs), and PMRs from 1995 to 2008 to approximately 1/4–1/3 for DZ twins and to 1/2 for both MZ twins and singletons. ENDRs and PMRs were the lowest at maternal ages (MAs) of 30–34 years for MZ and DZ twins and at 25–29 years for singletons. Each mortality rate in singletons was significantly lower at 25–29 years compared with those at other MAs. PMRs were significantly higher for MZ and DZ twins than for singletons in each MA group, except when MA was ≥40 years for DZ twins. PMR was the lowest at GA of 37 weeks for both MZ (6.6) and DZ (3.0) twins but was the lowest at GA of ≥40 weeks in singletons (1.1). PMRs were higher for both MZ and DZ twins than for singletons, except for GA of <36 weeks. PMR was significantly higher for MZ twins than for DZ twins for all GAs, except when GA was ≥39 weeks. The recent increase in preterm birth (i.e., GA of <37 weeks, excluding fetuses delivered at GA of <22 weeks) was associated with a reduction in PMRs for both MZ and DZ twins. Conclusion: In this Japanese population, PMRs decreased for zygotic twins and singletons between 1995 and 2008. The most marked decline was for DZ twins.
{"title":"Perinatal Mortality Rates and Risk Factors for Mortality among Zygotic Twins and Singletons in Japan, 1995-2008","authors":"Y. Imaizumi, K. Hayakawa","doi":"10.4172/2167-0897.1000188","DOIUrl":"https://doi.org/10.4172/2167-0897.1000188","url":null,"abstract":"Objective: We aimed to determine the perinatal mortality rates (PMRs) for monozygotic (MZ) twins, dizygotic (DZ) twins, and singletons, together with the associated risk factors for these PMRs. Study design: PMRs of zygotic twins and singletons were estimated using Japanese vital statistics from 1995 to 2008. \u0000Results: Declines were seen in fetal death rates [FDRs; defined as deaths after a gestational age of (GA) 22 weeks], early neonatal death rates (ENDRs), and PMRs from 1995 to 2008 to approximately 1/4–1/3 for DZ twins and to 1/2 for both MZ twins and singletons. ENDRs and PMRs were the lowest at maternal ages (MAs) of 30–34 years for MZ and DZ twins and at 25–29 years for singletons. Each mortality rate in singletons was significantly lower at 25–29 years compared with those at other MAs. PMRs were significantly higher for MZ and DZ twins than for singletons in each MA group, except when MA was ≥40 years for DZ twins. PMR was the lowest at GA of 37 weeks for both MZ (6.6) and DZ (3.0) twins but was the lowest at GA of ≥40 weeks in singletons (1.1). PMRs were higher for both MZ and DZ twins than for singletons, except for GA of <36 weeks. PMR was significantly higher for MZ twins than for DZ twins for all GAs, except when GA was ≥39 weeks. The recent increase in preterm birth (i.e., GA of <37 weeks, excluding fetuses delivered at GA of <22 weeks) was associated with a reduction in PMRs for both MZ and DZ twins. \u0000Conclusion: In this Japanese population, PMRs decreased for zygotic twins and singletons between 1995 and 2008. The most marked decline was for DZ twins.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"2015 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2015-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-10DOI: 10.4172/2167-0897.1000187
V. Manfredini, C. Cerini, C. Giovanettoni, E. Brazzoduro, R. Rezzonico
Metabolic bone disease is a frequent condition in very low birth weight (VLBW) infants In order to prevent the disease, the provision of high amount of calcium and phosphate in parenteral nutrition solutions and during transition to the full enteral feedings is crucial. Current practice supports early aggressive mineral supplementation. In this review, we will discuss data from the recent literature regarding the recommendation for supplementation of calcium, phosphate and vitamin D in VLBW infants and the interpretation of indirect markers of bone metabolism for screening, diagnosis and monitoring high risk infants, as well as to guide treatment.
{"title":"Metabolic Bone Disease of Prematurity: A Review of Minerals Supplementation and Disease Monitoring","authors":"V. Manfredini, C. Cerini, C. Giovanettoni, E. Brazzoduro, R. Rezzonico","doi":"10.4172/2167-0897.1000187","DOIUrl":"https://doi.org/10.4172/2167-0897.1000187","url":null,"abstract":"Metabolic bone disease is a frequent condition in very low birth weight (VLBW) infants In order to prevent the disease, the provision of high amount of calcium and phosphate in parenteral nutrition solutions and during transition to the full enteral feedings is crucial. Current practice supports early aggressive mineral supplementation. In this review, we will discuss data from the recent literature regarding the recommendation for supplementation of calcium, phosphate and vitamin D in VLBW infants and the interpretation of indirect markers of bone metabolism for screening, diagnosis and monitoring high risk infants, as well as to guide treatment.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2015-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0897.1000187","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-10DOI: 10.4172/2167-0897.1000186
Hesham Al-Saloos
Congenital high airway obstruction syndrome (CHAOS) includes laryngeal atresia and tracheal agenesis which are rare and potentially lethal conditions. We describe a newborn term infant with laryngeal atresia and tracheal agenesis with a distal tracheo-esophageal fistula (TEF). He also had a double outlet right ventricle (DORV) and a persistent left superior vena cava (LSVC). To our knowledge this is the first report of this association.
{"title":"Case of Laryngeal Atresia, Tracheal Agenesis, Tracheo-Esophageal Fistula, Double Outlet Right Ventricle and Persistent Left Superior Vena Cava","authors":"Hesham Al-Saloos","doi":"10.4172/2167-0897.1000186","DOIUrl":"https://doi.org/10.4172/2167-0897.1000186","url":null,"abstract":"Congenital high airway obstruction syndrome (CHAOS) includes laryngeal atresia and tracheal agenesis which are rare and potentially lethal conditions. We describe a newborn term infant with laryngeal atresia and tracheal agenesis with a distal tracheo-esophageal fistula (TEF). He also had a double outlet right ventricle (DORV) and a persistent left superior vena cava (LSVC). To our knowledge this is the first report of this association.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"2015 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2015-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0897.1000186","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-10DOI: 10.4172/2167-0897.1000185
R. Jose, Pushplata Kumari, R. Vijayaselvi, M. Beck
{"title":"Audit to Assess the Implementation of Early First Feeding in Newborns after Caesarean Delivery","authors":"R. Jose, Pushplata Kumari, R. Vijayaselvi, M. Beck","doi":"10.4172/2167-0897.1000185","DOIUrl":"https://doi.org/10.4172/2167-0897.1000185","url":null,"abstract":"","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2015-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0897.1000185","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-07DOI: 10.4172/2167-0897.1000184
M. Abiodun, R. Oluwafemi, O. Fabunmi, Temitope Ajimuda
Congenital neck masses include branchial cleft cysts, thyroglossal duct cysts, thymus cysts, dermoid and teratoma, vascular abnormalities, and lymphatic malformations such as cystic hygroma. Cervical Teratomas (CTs) are rare true neoplasm of the neck composed of tissues derived from at least two of the three embryonic germ layers but foreign to the anatomic site of occurrence. CTs occur on the anterolateral surface of the neck, extending midline from the thyroid gland. They are asymmetric and multinodular with a cystic-solid consistency. In contrast, Cystic Hygromas (CHs) are benign multiloculated, compressible, painless lymphatic lesions with a doughy consistency. CHs can occur in the submental triangle, with extension into the floor of mouth. Early neonatal presentation with aero-digestive obstruction is the norm for large CTs and CHs. We present two infants with huge CT and CH delivered in two consecutive years at our facility in south-western Nigeria by unrelated families. Definitive prenatal diagnoses were not made and deliveries were not pre-planned. Both infants had severe respiratory compromise and unfavorable outcome. This report aims to enhance clinical recognition of these rarities, highlight their occurrence in our locale and reiterate the associated management challenges in resource-limited settings. Relevant literatures are also reviewed.
{"title":"Cervical Teratoma and Cystic Hygroma in Nigerian Infants: Case Studies of Two Differential Diagnoses of Neonatal Neck Mass and Review of the Literature","authors":"M. Abiodun, R. Oluwafemi, O. Fabunmi, Temitope Ajimuda","doi":"10.4172/2167-0897.1000184","DOIUrl":"https://doi.org/10.4172/2167-0897.1000184","url":null,"abstract":"Congenital neck masses include branchial cleft cysts, thyroglossal duct cysts, thymus cysts, dermoid and teratoma, vascular abnormalities, and lymphatic malformations such as cystic hygroma. Cervical Teratomas (CTs) are rare true neoplasm of the neck composed of tissues derived from at least two of the three embryonic germ layers but foreign to the anatomic site of occurrence. CTs occur on the anterolateral surface of the neck, extending midline from the thyroid gland. They are asymmetric and multinodular with a cystic-solid consistency. In contrast, Cystic Hygromas (CHs) are benign multiloculated, compressible, painless lymphatic lesions with a doughy consistency. CHs can occur in the submental triangle, with extension into the floor of mouth. Early neonatal presentation with aero-digestive obstruction is the norm for large CTs and CHs. We present two infants with huge CT and CH delivered in two consecutive years at our facility in south-western Nigeria by unrelated families. Definitive prenatal diagnoses were not made and deliveries were not pre-planned. Both infants had severe respiratory compromise and unfavorable outcome. This report aims to enhance clinical recognition of these rarities, highlight their occurrence in our locale and reiterate the associated management challenges in resource-limited settings. Relevant literatures are also reviewed.","PeriodicalId":73850,"journal":{"name":"Journal of neonatal biology","volume":"4 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2015-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0897.1000184","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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