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Editorial note for the Special Issue “Neonatal Management during the Coronavirus Disease” 特刊“冠状病毒病期间的新生儿管理”社论说明
Pub Date : 2020-01-01 DOI: 10.35248/2167-0897.20.9.E279
Naoko Horii
A rapidly developing area of science and technology involves research about the interactions over newborn. Over the past half century, Neonatology is a subspecialty of pediatrics that consists of the medical care of newborn infants, especially the ill or premature newborn. It is a hospital-based specialty, and is usually practised in neonatal intensive care units (NICUs). The principal patients of neonatologists are newborn infants who are ill or require special medical care due to prematurity, low birth weight, intrauterine growth restriction, congenital malformations (birth defects), sepsis, pulmonary hypoplasia or birth asphyxia.
新生儿相互作用的研究是一个迅速发展的科学技术领域。在过去的半个世纪里,新生儿科是儿科的一个亚专科,包括新生儿的医疗护理,特别是生病或早产的新生儿。这是一种以医院为基础的专科,通常在新生儿重症监护病房(NICUs)进行。新生儿专科医生的主要病人是由于早产、出生体重低、宫内生长受限、先天性畸形(出生缺陷)、败血症、肺发育不全或出生窒息而生病或需要特殊医疗护理的新生儿。
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引用次数: 3
Editorial Note for Journal of Neonatal Biology 《新生儿生物学杂志》编辑说明
Pub Date : 2020-01-01 DOI: 10.35248/2167-0897.20.9.E001
Sowmya Sakinala
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引用次数: 0
Short Term and Long term Outcome of Single-Stage Trans-anal Pull Through for Hirschsprung's Disease in Neonates and Infants 新生儿和婴儿先天性巨结肠病单期经肛门拔除的近期和长期疗效
Pub Date : 2020-01-01 DOI: 10.35248/2167-0897.20.9.277
S. Wani, G. Mufti, K. Rashid, N. Bhat, A. Baba
Purpose: Hirschsprungs disease is common cause of intestinal obstruction in neonate and trans-anal pull through has drastically changed the treatment of Hirschsprungs disease. The aim of this study was to evaluate the short and long-term outcome of single-stage trans-anal pull through in neonates and infants. Material and methods: It was a prospective study of new-born’s and young infants with features of Hirschsprungs disease. Patients with weight more than 3 kg, transition zone at recto sigmoid and distal sigmoid region were included in the study. Patients with more dilated proximal colon, bowel obstruction not responding to washes and long segment Hirschsprungs disease were excluded from the study. Single-stage trans-anal pull through was done in all cases and short term variables include wound infection, leak, peri-anal excoriation and long term outcome variables included continence, constipation, stricture, enterocolitis and need of redo pull-through procedure were evaluated. Results: 24 patients were included in the study. There were 15 males and 9 females. Age of the patients ranged from 26 days to 4.5 months with mean age of 1.3 months. Weight of the patients ranged from 3 kg to 5.3 kg with mean weight of 4.8 kg. Wound infection and perianal excoriation was seen in 8.3% and 45.8% respectively. Enterocolitis, stricture, constipation and minor soiling were seen in 12.5%, 4.2%, 8.3% and 12.5% respectively. Follow-up period ranged from 10 to 120 months. Conclusion: Trans-anal pull through is feasible and safe option with excellent results in neonates and infants with short segment Hirschsprungs disease.
目的:先天性巨结肠病是新生儿肠梗阻的常见原因,经肛拉通术彻底改变了先天性巨结肠病的治疗方法。本研究的目的是评估新生儿和婴儿单期经肛门牵引术的短期和长期结果。材料与方法:本研究是一项前瞻性研究,研究对象为有先天性巨裂病特征的新生儿和幼龄婴儿。体重大于3kg、乙状结肠直肠和乙状结肠远端过渡区纳入研究。近端结肠扩张程度较高、洗涤无效的肠梗阻和长段先天性巨结肠病的患者被排除在研究之外。所有病例均进行单期肛门拉通,评估短期变量包括伤口感染、渗漏、肛周刮伤,长期结果变量包括失禁、便秘、狭窄、小肠结肠炎和重新拉通手术的需要。结果:24例患者纳入研究。其中男性15人,女性9人。患者年龄26 ~ 4.5个月,平均年龄1.3个月。患者体重3 ~ 5.3 kg,平均体重4.8 kg。伤口感染和肛周刮伤分别占8.3%和45.8%。小肠结肠炎、狭窄、便秘和轻微脏污分别占12.5%、4.2%、8.3%和12.5%。随访10 ~ 120个月。结论:经肛拉通是治疗新生儿和婴儿短节段先天性先天性先天性先天性先天性先天性畸形的一种安全可行的方法。
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引用次数: 1
Predictors of neurodevelopmental outcome in newborn treated with hypothermia therapy 低温治疗新生儿神经发育结局的预测因素
Pub Date : 2018-12-10 DOI: 10.4172/2167-0897-C3-015
pMinkyo Chunp
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引用次数: 0
Improving the outcomes of preterm infants-introducing the preterm pig as a translational model for improving NICU protocols and practices 改善早产儿的预后-介绍早产猪作为改善新生儿重症监护病房协议和实践的翻译模型
Pub Date : 2018-12-10 DOI: 10.4172/2167-0897-c3-013
al K Buddingtonp
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引用次数: 0
Long-term Follow Up of Patients Treated with D-Penicillamine in the Neonatal Period D-青霉胺治疗新生儿期患者的长期随访
Pub Date : 2018-05-05 DOI: 10.4172/2167-0897.1000270
I. Pataki, G. Balla, A. Nagy, A. Berkes, Anna Szolos, B. Bíró, G. Veres, L. Lakatos
Background: In neonatal therapy D-penicillamine (D-PA) was first recognized to have a potential benefit for neonatal hyperbilirubinemia in the early 1970s. Controlled, randomized clinical trials confirmed the effectiveness of D-PA in the treatment of haemolytic disease of the newborn and retinopathy of prematurity. The aim of this study was to explore potential long-term effects of D-PA by measuring health state of adults treated with this drug in the newborn period. Methods: The self-perceived health and health related quality of life (HRQoL) have been investigated in a cohort of 23-36 years old patients using the EuroQol5D instrument. Self-administered questionnaires were mailed comprising EQ-5D instrument and questions on academic achievements, and presence of neurosensory impairments. The original cohort consisted of 1492 subjects. 518 participants returned the questionnaires, of which 32 had to be excluded due to incomplete responses. As reference, the data of the quality of life survey was used; this study was conducted in the early years of 2000, on a representative sample of 5503 members of a Hungarian population with average achievement [22]. Results: The occurrence of neurosensory disabilities and educational levels on HRQoL were also evaluated. The authors have examined the bias between those who returned complete questionnaires and those who returned incomplete questionnaires. In all age groups of the cohort the mean Visual Analogue Scale (VAS) score was remarkable higher, whereas the mean EQ-5D index was lower than the Hungarian age specific value, which discordance can be explained by the "disability paradox". Significantly more respondents with VLBW compared to their term peers reported to have neurosensory impairment and lower educational level. Conclusions: The different characteristics of incomplete respondents can lead to large biases and through that way have great influence on HRQoL estimates. Focusing on the potential effects of D-PA, the following facts are verifiable: (i) adults survivors of prematurity can suffer from numerous pathological conditions. Consequently, their health/behaviors were significantly weaker (as it was expected) in comparison with the average population's examined [22] (ii) on the other hand, those adults who were born at term, their health/behaviors were better. This was, however, statistically not significant.
背景:在新生儿治疗中,D-青霉素(D-PA)在20世纪70年代初首次被认为对新生儿高胆红素血症有潜在益处。对照、随机临床试验证实了D-PA治疗新生儿溶血性疾病和早产儿视网膜病变的有效性。本研究的目的是通过测量新生儿期使用该药物治疗的成年人的健康状况,探索D-PA的潜在长期影响。方法:使用EuroQol5D仪器对23-36岁患者的自我感知健康和健康相关生活质量(HRQoL)进行调查。邮寄了自我管理的问卷,包括EQ-5D仪器和关于学术成就和是否存在神经感觉障碍的问题。最初的队列包括1492名受试者。518名参与者返回了问卷,其中32人因回答不完整而被排除在外。作为参考,使用了生活质量调查的数据;这项研究于2000年初进行,以5503名成绩平均的匈牙利人为代表进行[22]。结果:还评估了神经感觉障碍的发生率和HRQoL的教育水平。作者研究了那些返回完整问卷的人和那些返回不完整问卷的人们之间的偏差。在该队列的所有年龄组中,平均视觉模拟量表(VAS)得分显著较高,而平均EQ-5D指数低于匈牙利特定年龄值,这种不一致可以用“残疾悖论”来解释。与同期同龄人相比,极低出生体重的受访者报告有神经感觉障碍和较低的教育水平。结论:不完全调查对象的不同特征会导致很大的偏差,从而对HRQoL估计产生很大影响。关注D-PA的潜在影响,以下事实是可验证的:(i)早产的成年幸存者可能患有多种病理状况。因此,与检查的平均人群相比,他们的健康/行为明显较弱(正如预期的那样)[22](ii)另一方面,那些足月出生的成年人,他们的身体健康/行为更好。然而,这在统计上并不显著。
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引用次数: 2
Efficacy of Intensive Phototherapy in Management of Neonatal Hyperbilirubinemia in Neonatal Unit of Assiut University Children Hospital 阿苏特大学儿童医院新生儿科强化光疗治疗新生儿高胆红素血症的疗效观察
Pub Date : 2017-12-22 DOI: 10.4172/2167-0897.1000266
Abdel-Halim Ks, Soliman Aa, Askar Eaa
Objective: To assess the effectiveness of intensive phototherapy in comparison with conventional phototherapy in reducing the need for exchange transfusion and the duration of phototherapy for management of neonatal hyperbilirubinemia in Neonatal Unit of Assiut University Children Hospital. Methods: The prospective study was conducted from March 2016 to February 2017 and comprised neonates with indirect hyperbilirubinaemia near the level of ECT who were admitted to the Neonatal Unit of Assiut University Children Hospital and treated with intensive phototherapy (group 1). These neonates were compared with a historical retrospective group who had been treated with conventional therapy from March 2012 to February 2013 (group 2). Both groups were subjected to complete clinical evaluation and laboratory investigations. Results: The use of intensive phototherapy in the treatment of indirect pathological hyperbilirubinaemia is very effective in lowering total serum Bilirubin when its level is within 2-3 mg/dl (34-50 umol/l) of the exchange transfusion level and it has succeeded in reducing the frequency of exchange transfusion with its hazards and serious complications. It has also succeeded in reducing the duration of phototherapy and subsequently the duration of hospital stay and economic burden. Conclusion: The use of intensive phototherapy in the treatment of indirect pathological hyperbilirubinaemia is as effective as exchange transfusion in lowering Total Serum Bilirubin when its level is within 2-3 mg/dl (34-51 μmol/l) of the exchange level and it is effective in reducing needs for exchange transfusion and duration of phototherapy.
目的:在阿西乌大学儿童医院新生儿病房,评估强化光疗与传统光疗在减少新生儿高胆红素血症换血需求和光疗持续时间方面的有效性。方法:该前瞻性研究于2016年3月至2017年2月进行,包括入住阿西尤特大学儿童医院新生儿病房并接受强化光疗的间接高胆红素血症接近ECT水平的新生儿(第1组)。将这些新生儿与2012年3月至2013年2月接受常规治疗的历史回顾性组(第2组)进行比较。两组均接受了完整的临床评估和实验室调查。结果:当血清总胆红素水平在换血水平的2-3mg/dl(34-50umol/l)范围内时,使用强化光疗治疗间接病理性高胆红素血症是非常有效的,并且成功地降低了换血频率及其危险性和严重并发症。它还成功地缩短了光疗的持续时间,随后缩短了住院时间和经济负担。结论:当血清总胆红素水平在交换水平的2-3mg/dl(34-51μmol/l)范围内时,在治疗间接病理性高胆红素血症中使用强化光疗与交换输注一样有效,并且在减少交换输注需求和光疗持续时间方面是有效的。
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引用次数: 8
Knowledge, Attitude and Practice of Kangaroo Mother Care by Postnatal Mothers who Gave Birth to Preterm and Low Birth Weight Babies in Public Hospitals, Eastern Ethiopia 埃塞俄比亚东部公立医院分娩早产和低出生体重婴儿的产后母亲对袋鼠妈妈的护理知识、态度和实践
Pub Date : 2017-11-27 DOI: 10.4172/2167-0897.1000264
Aklilu Abrham Roba, S. Binoy, M. A. Naganuri
Introduction: Globally, babies born with low birth weight and preterm accounts for 25 million and 15 million respectively. The magnitude of preterm and low birth weight was 29.1% in Ethiopia by 2011. Around 70% neonatal deaths occur in low birth weight and preterm babies. Most studies demonstrated kangaroo mother care to be more effective than incubator care for these neonates but there are limited studies in Ethiopia. Therefore, the main aim of the study was to assess the acceptability, knowledge, attitude and practice of kangaroo mother care in public hospitals. Methods: A descriptive cross-sectional study was conducted among postnatal mothers of preterm and low birth weight babies in Dilchora and Hiwot Fana Specialized hospital from October 1, 2015 to June 25, 2016. Data were collected by interviewing 349 mothers by a pretested questionnaire. It was entered in to Epi Data software version 3.1 and exported to SPSS version 20 for analysis. Results: 69.91% of mothers mentioned the benefits of kangaroo mother care correctly. The majority of mothers 221 (63.33%) felt positive regarding implementation of Kangaroo Mother Care for it corrects the temperature, increase attachment and improve the growth of their small babies. On the other hand, 195 (55.87%) believed that Kangaroo Mother Care has positive effect on breast feeding. During the study period, 189 (54.15%) mothers practiced Kangaroo Mother Care in hospitals and also willing to continue at home. The mean duration of Kangaroo Mother Care was 2 h/day. Conclusion: The majority of mothers felt positive regarding implementation of Kangaroo Mother Care. The study also revealed that more than half of the study participants practiced Kangaroo Mother Care in hospitals and also willing to continue at home. Therefore, it will be crucial if there are health education sessions during antenatal care follow-up for complete acceptance of Kangaroo Mother Care after delivery.
导语:在全球范围内,低出生体重婴儿和早产婴儿分别占2500万和1500万。到2011年,埃塞俄比亚早产和低出生体重的比例为29.1%。约70%的新生儿死亡发生在低出生体重和早产儿中。大多数研究表明,袋鼠妈妈护理比孵化器护理对这些新生儿更有效,但在埃塞俄比亚的研究有限。因此,本研究的主要目的是评估公立医院对袋鼠妈妈护理的接受程度、知识、态度和实践。方法:对2015年10月1日至2016年6月25日在Dilchora和Hiwot Fana专科医院出生的早产儿和低出生体重儿的产后母亲进行描述性横断面研究。通过预测问卷采访349名母亲收集数据。输入Epi Data软件3.1版,导出到SPSS 20版进行分析。结果:69.91%的妈妈正确地提到了袋鼠妈妈护理的好处。大多数母亲221(63.33%)对袋鼠妈妈护理的实施持积极态度,因为它纠正了温度,增加了依恋,促进了小婴儿的生长。另一方面,195人(55.87%)认为袋鼠妈妈护理对母乳喂养有积极作用。在研究期间,189名(54.15%)母亲在医院实行袋鼠式母亲护理,并愿意在家中继续实行。袋鼠妈妈护理的平均时间为2小时/天。结论:大多数母亲对袋鼠妈妈护理的实施持积极态度。研究还显示,超过一半的研究参与者在医院实行袋鼠妈妈护理,并愿意在家里继续。因此,如果在产前护理随访期间有健康教育课程,以便在分娩后完全接受袋鼠妈妈护理,这将是至关重要的。
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引用次数: 16
Frequency and Timing of Antenatal Care Visits and Its Impact on Neonatal Mortality in EAG States of India 印度EAG州产前护理就诊的频率和时间及其对新生儿死亡率的影响
Pub Date : 2017-11-01 DOI: 10.4172/2167-0897.1000263
Rishabh Gupta, Bedanga Talukdar
The study aims to examine the association between frequency of antenatal care visits and neonatal mortality in EAG states and to explore the relationship between the timing of first antenatal care visit in the trimester and neonatal mortality in EAG states of India. The study uses data from the third round of National Family Health Survey NFHS-3. The timing of the first antenatal visit and the relative number of ANC visits received by the women is studied separately. Logistic regression is applied to find an association between continuity, the timing of ANC received and neonatal birth outcome. Results explain significant association between mothers receiving ANC 4-9 visits had experienced a lower risk of neonatal mortality. Mothers who received antenatal care visit from the first trimester experienced lest pregnancy outcomes and neonatal deaths.
该研究旨在检验EAG州产前护理就诊频率与新生儿死亡率之间的关系,并探讨印度EAG州妊娠期首次产前护理就诊时间与新生儿死亡率的关系。该研究使用了第三轮全国家庭健康调查NFHS-3的数据。第一次产前检查的时间和妇女接受ANC检查的相对次数分别进行了研究。应用Logistic回归来寻找连续性、接受ANC的时间和新生儿出生结果之间的相关性。结果解释了接受ANC4-9访视的母亲新生儿死亡率较低之间的显著相关性。从孕早期开始接受产前护理的母亲经历了最糟糕的妊娠结局和新生儿死亡。
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引用次数: 28
Time of Birth and Seasonal Variations Influence on Weight Loss in Breastfeeding Neonates [Retracted ] 出生时间和季节变化对母乳喂养新生儿体重减轻的影响
Pub Date : 2017-10-03 DOI: 10.4172/2167-0897.1000262
M. Zia, L. Lemon, Jessica L. Kinney, Sabrina Nitkowski-Keever, U. Paudel
Breastfeeding (BF) neonates generally lose weight after birth. Diurnal and nocturnal factors as well as season may affect BF. The aim of this study was to determine the effect of birth time and seasonal variations on weight loss in BF new-borns. In this retrospective study, two sets of groups were evaluated. Birth time groups (night time: 7 pm-7 am and day time: 7 am-7 pm) and seasonal variations groups (summer, autumn, winter and spring). Weight loss of more than 5%, 7%, 10% at 5% of birth weight at 7% weight at 10% at 12 h were significant contributing factors. Seasonal variations were not associated with weight loss in new-borns. Conclusion: BF babies born at night time lose significant weight during the first two days of life. Seasonal variations did not affect weight loss.
母乳喂养(BF)新生儿通常在出生后体重会减轻。昼夜因素以及季节可能会影响BF。本研究的目的是确定出生时间和季节变化对BF新生儿体重减轻的影响。在这项回顾性研究中,对两组患者进行了评估。出生时间组(夜间:上午7点至7点,白天:上午7时至7点)和季节变化组(夏季、秋季、冬季和春季)。出生12小时时体重下降超过出生体重的5%、7%、10%(出生体重为7%、出生体重为10%)是重要的影响因素。季节变化与新生儿体重减轻无关。结论:夜间出生的BF婴儿在出生后的头两天体重明显减轻。季节变化不会影响体重减轻。
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引用次数: 0
期刊
Journal of neonatal biology
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