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Severe Intraventricular Hemorrhage is Associated with Lung Injury in Preterm Infants on Mechanical Ventilation. 使用机械通气的早产儿严重脑室内出血与肺损伤有关。
Pub Date : 2023-01-01 Epub Date: 2023-11-29 DOI: 10.26502/jppch.74050168
Monika Piatek, Elie G Abu Jawdeh, Peter Giannone, Brandon Miller, Aric Schadler, Mina Hanna

Background: The aim of this study was to better understand the relationship between intraventricular hemorrhage and the risk of development of early lung disease in extremely low birth weight infants. We hypothesize that infants with severe intraventricular hemorrhage have higher respiratory severity scores than infants with mild/no intraventricular hemorrhage within the first 7 days of life.

Methods: This was a single center retrospective study conducted on subjects born between 01/01/2018 and 06/30/2021 at the University of Kentucky Children's Hospital NICU. We enrolled preterm infants with gestational age of less than 30 weeks and birth weight of less than 1000 grams who were placed on mechanical ventilation on admission.

Results: We found a clinically significant increasing trend of respiratory severity scores within the first week of life in the group of infants with severe intraventricular hemorrhage.

Conclusion: This study is first to show that severe intraventricular hemorrhage is associated with higher respiratory severity scores predicting early lung injury in the extremely low birth weight infants placed on a mechanical ventilator within the first 7 days of life.

研究背景本研究旨在更好地了解极低出生体重儿脑室内出血与早期肺部疾病发病风险之间的关系。我们假设,在出生后 7 天内,有严重脑室内出血的婴儿比轻度/无脑室内出血的婴儿有更高的呼吸系统严重程度评分:这是一项单中心回顾性研究,研究对象为2018年1月1日至2021年6月30日期间在肯塔基大学儿童医院新生儿重症监护室出生的婴儿。我们招募了胎龄小于 30 周、出生体重小于 1000 克、入院时接受机械通气的早产儿:结果:我们发现,在严重脑室内出血的婴儿组中,呼吸系统严重程度评分在出生后第一周内呈明显的临床上升趋势:本研究首次表明,严重的脑室内出血与较高的呼吸系统严重程度评分有关,而呼吸系统严重程度评分可预测出生后 7 天内使用机械呼吸机的极低出生体重儿的早期肺损伤。
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引用次数: 0
A Rare Case of Childhood Hepatitis A Infection with Bilateral Pleural Effusion Acalculous Cholecystitis and Massive Ascites 儿童甲型肝炎感染合并双侧胸腔积液、无结石性胆囊炎及大量腹水一例
Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050140
Ranjum, Naina Nanda, Nitya Sehgal, Susheel kumar saini, Vinay Gahlot, Keerthana Anigani, Tushar Jagat, Ajay kumar saini, S. Kumari
Hepatitis A virus infections are mostly asymptomatic or mildly symptomatic in pediatric population. Generally this disease has a benign course and resolves spontaneously. However, intrahepatic and extrahepatic manifestations can complicate typical course of acute hepatitis A in children. Pleural effusion, acalculous cholecystitis and ascites are extremely rare extrahepatic complications. Pleural effusion or ascites does not change the prognosis or require any invasive treatment usually. We report a case of 8 years old boy presented with both pleural effusion and gross ascites accompanying hepatitis A infection. Diagnosis was done using serological testing and imaging studies. He was treated with supportive management only with full recovery after 4 weeks.
甲型肝炎病毒感染在儿科人群中多为无症状或轻度症状。本病一般为良性病程,可自行消退。然而,肝内和肝外表现可使儿童急性甲型肝炎的典型病程复杂化。胸腔积液、无结石性胆囊炎和腹水是极为罕见的肝外并发症。胸腔积液或腹水通常不会改变预后或需要任何侵入性治疗。我们报告一例8岁男童,同时表现为胸腔积液和腹水,并伴有甲型肝炎感染。诊断通过血清学检查和影像学检查完成。患者接受支持性治疗,4周后完全康复。
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引用次数: 0
Epidemiological-Clinical and Evolution Profile of Rotavirus Infection in Four Hospital Structures in Kinshasa 金沙萨四所医院轮状病毒感染的流行病学-临床和演变概况
Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050150
Virginie MUJINGA MULUMBA, Loukia AKETI PAIZANOS, Freddy BYAMUNGU MBOKO, Joseph SHIKU DIAYISU, Pierre Tshibassu Manianga, J. M. Tamfum
Affiliation: 1Cardio-Pneumology and Infectious Diseases service, Department of Pediatrics, Kinshasa University Clinics, Democratic Republic of the Congo 2Gastroenterology, neurology and endocrinology service, Department of Pediatrics/Kinshasa University Clinics, Democratic Republic of the Congo 3Pediatric Society of Congo-Democratic, Kinshasa, Democratic Republic of the Congo 4Microbiology Service, Department of Clinical Biology/Kinshasa University Clinics and National Institute of Biomedical Research, Democratic Republic of the Congo
联系:1刚果民主共和国金沙萨大学诊所儿科心脏肺炎和传染病科2刚果民主共和国金沙萨大学诊所儿科消化病学、神经病学和内分泌科3刚果民主共和国金沙萨儿科学会4微生物科临床生物学科金沙萨大学诊所国家生物医学研究所刚果民主共和国
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引用次数: 0
The Effect of Admission Hypothermia on Newborn 入院时低温对新生儿的影响
Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050155
A. Almudeer, Muneerah Najmi, Easa Magfori, Mohd Salwi
Objective: Consequences of hypothermia is associated with higher mortality and morbidity therefore, thermal control following delivery is an essential of neonatal care. We decided to learn more about thermal regulating procedures in our unit. The goal of this study was to determine the temperature at the time of admission to our neonatal intensive care units (NICUs) and how it relates to death and other morbidity. We also interested to look into the newborn interventions after delivery to control temperature and see how these interventions affect thermal regulation. Methods: Prospective cohort study using perinatal chart review data for all babies admitted to the NICU at King Fahd central hospital in Jazan. 300 babies through period of April 2021 to March 2022. Hypothermia was classified according to WHO definition as mild (36–36.5°C), moderate (32–35.9°C), or severe (32°C) when the temperature dropped below 36.5°C. We used a multivariable logistic regression analysis to investigate the adjusted effect of hypothermia on neonatal mortality and complications The regression analysis results were provided as crude/unadjusted odds ratios (OR) and adjusted odds ratios (AOR) with 95% confidence intervals (CIs). Results: Of the infants included in the dataset Almost half of them (49.3%) had abnormal body temperature, 20.7%, 11.3%, and 17.3% had mild, moderate, and severe hypothermia respectively. Around 20% of newborns were given a bath 2 hours after birth, 36% their head covered with hats, and 21.7% had skin-to-skin contact. The adjusted model found that newborns with severe hypothermia were 0.53 (OR = 0.53; [95% CI: 0.15-1.83]) times likely to die and 2.04 (OR = 2.04; [95% CI: 0.76-5.46]) times likely to develop any complication when compared to newborns without hypothermia. Newborns with low birth weight (OR = 16.5; [95% CI: 1.47-185.7]) and without skin-to-skin contact (OR = 3.27; [95% CI: 1.33-8.04]) were more likely to develop any complication when compared to those with skin-to-skin contact. Conclusion: Hypothermia, low birth weight, abnormal CBC, and absence of skin-to-skin contact all raise the risk of neonatal morbidity, according to this study. According to the study, thermal regulation techniques such as head coverings, skin-to-skin contact, and delayed bathing are not widespread in Saudi Arabian hospitals. These findings call for a review of the procedures or recommendations, as well as an assessment of how well the thermal regulation rules are being followed in NICUs.
目的:低温的后果与较高的死亡率和发病率相关,因此,分娩后的热控制是新生儿护理的必要条件。我们决定更多地了解我们单位的热调节程序。本研究的目的是确定新生儿重症监护病房(NICUs)入院时的体温及其与死亡和其他发病率的关系。我们也有兴趣研究新生儿分娩后的干预措施,以控制体温,看看这些干预措施如何影响体温调节。方法:前瞻性队列研究,使用围产期图表回顾数据,对2021年4月至2022年3月期间在吉赞法赫德国王中心医院收治的所有新生儿重症监护室的300名婴儿进行研究。根据世卫组织的定义,低温分为轻度(36-36.5°C)、中度(32 - 35.9°C)和重度(32°C),当温度降至36.5°C以下时。我们使用多变量logistic回归分析来研究低温对新生儿死亡率和并发症的调整效应,回归分析结果以95%置信区间(ci)的粗/未调整优势比(OR)和调整优势比(AOR)提供。结果:在数据集中的婴儿中,近一半(49.3%)的婴儿体温异常,分别为20.7%、11.3%和17.3%的婴儿出现轻度、中度和重度体温过低。约20%的新生儿在出生后2小时洗澡,36%的新生儿戴上帽子,21.7%的新生儿有皮肤接触。调整后的模型发现,新生儿严重低温的发生率为0.53 (OR = 0.53;[95% CI: 0.15-1.83])和2.04 (OR = 2.04;[95% CI: 0.76-5.46])发生并发症的可能性是无低温新生儿的两倍。低出生体重新生儿(OR = 16.5;[95% CI: 1.47-185.7])和无皮肤接触(OR = 3.27;[95% CI: 1.33-8.04])与皮肤接触的患者相比,更容易出现任何并发症。结论:根据这项研究,低温、低出生体重、异常CBC和缺乏皮肤接触都会增加新生儿发病的风险。根据这项研究,在沙特阿拉伯的医院里,戴头巾、皮肤接触和延迟洗澡等热调节技术并不普遍。这些发现要求对这些程序或建议进行审查,并评估新生儿重症监护病房的热调节规则的执行情况。
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引用次数: 0
Occupational Dermatoses in Health Care Personnel Using PPE during the COVID Pandemic COVID大流行期间使用个人防护装备的卫生保健人员的职业性皮肤病
Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050163
Dinesh P Asati, Kapil Baheti, Maninder Kaur, Suman Patra, Kritika Singhal Singhal
Background: A sudden surge of occupation-associated dermatoses among the healthcare workers (HCWs) serving COVID-19 patients have been witnessed recently due to increased usage of PPE (PPE) kits and increased frequency of hygiene practices, with a significant impact on their quality of life and compromised efficacy at work. Hence, this study was conducted to measure the prevalence of occupational dermatoses among HCWs serving Covid-19 patients using PPE kits and hygiene practices and their impact on quality of life.
背景:由于个人防护用品(PPE)包的使用增加和卫生习惯的频率增加,最近在为COVID-19患者服务的卫生保健工作者(HCWs)中出现了职业相关皮肤病的突然激增,对他们的生活质量产生了重大影响,并降低了工作效率。因此,本研究旨在测量使用个人防护用品和卫生习惯为Covid-19患者服务的医护人员中职业性皮肤病的患病率及其对生活质量的影响。
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引用次数: 0
Musculoskeletal Disorders among the Mothers having Children with Cerebral Palsy 脑瘫患儿母亲的肌肉骨骼疾病
Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050161
Zannatul Mawa, Mohima Benojir, Ruksana Akter, Shameem Ahammad, Faruq Ahmed, Mohammad Nazmul Hasan, Nadia Afrin Urme, Shahid Afridi
Background: Cerebral Palsy (CP) is a collection of mobility and postural problems. Parents, particularly mothers, care for CP children. Caring for a kid with CP can be physically taxing and cause moms to acquire musculoskeletal ailments. CP moms have a greater risk of musculoskeletal issues than mothers of generally developing children. There is little study on musculoskeletal issues in Bangladeshi moms of CP children. This study examined the frequency and symptoms of musculoskeletal diseases in Bangladeshi moms of CP children.
背景:脑瘫(CP)是一种活动和姿势问题的集合。父母,尤其是母亲,照顾CP儿童。照顾一个患有CP的孩子可能会给身体带来负担,并导致母亲患上肌肉骨骼疾病。与正常发育儿童的母亲相比,患有慢性阻塞性肺病的母亲患肌肉骨骼问题的风险更大。关于患有CP儿童的孟加拉国母亲的肌肉骨骼问题的研究很少。本研究调查了孟加拉国CP儿童母亲肌肉骨骼疾病的频率和症状。
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引用次数: 0
Real-World HbF Status in Sickle Cell Disease from an Endemic Zone 镰状细胞病流行区真实世界HbF状况
Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050138
D. Pendharkar, G. Nirmal, Neha Gupta, A. Raj
,
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引用次数: 0
The effect of Epidural Analgesia on Maternal and Early Neonatal Outcomes, in Qatar State 硬膜外镇痛对卡塔尔产妇和早期新生儿结局的影响
Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050144
Ismail Sabry Abdelhady, E. Salama, Ashraf I. Gad, S. Ahmed, Alaa Masry
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引用次数: 0
Primary Central Nervous System Vasculitis in Childhood (cPACNS): A Case Series Study 儿童原发性中枢神经系统血管炎(cPACNS):一个病例系列研究
Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050156
Farhad Salehzadeh MD, Adel Ahadi MD, Omid Akbari MD
,
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引用次数: 0
Hematopoietic Stem Cell Transplantation for Sickle Cell Disease: A Review 造血干细胞移植治疗镰状细胞病的研究进展
Pub Date : 2023-01-01 DOI: 10.26502/jppch.74050143
Dinesh Pendharkar MD PhD FASCO, Garima Nirmal MD DM
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引用次数: 0
期刊
Journal of pediatrics, perinatology and child health
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