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A Scoping Review on Randomized Controlled Trials Investigating Effects of Breathwork in Women With Breast Cancer 研究呼吸呼吸对乳腺癌妇女影响的随机对照试验的范围综述
Q3 Medicine Pub Date : 2025-07-08 DOI: 10.1002/lim2.70033
Vinitha Ganesan, Kathryn A. Kaiser, Anjani Allada, Alekhya Puppala, David K. White, Mia Mugavero, Akhila Maruvada, Jade Kyle, Harshitha Gutta, Nusrat Jahan, Keerthi Gogineni, Megan Bell, Ritu Aneja

Background

Patients with breast cancer experience distress, treatment-related discomfort, and fear of recurrence from initial diagnosis through survivorship.

Aims

This study aimed to assess the effects of breathwork interventions on the mental health and quality of life of breast cancer patients and survivors.

Methods

We searched multiple databases for randomized controlled trials involving breathwork interventions in patients with breast cancer.

Results

Of the 5909 items screened, 16 studies involving 1726 participants met the inclusion criteria. Breathing interventions included yoga (n = 9), qigong (n = 4), and other breathing techniques (n = 3). We found that the highest average risk of bias was in the randomization process, with challenges in accurately evaluating deviations from intended interventions due to unquantified adherence to at-home practices, although overall bias in the included studies was generally low. Interventions were prescribed daily or weekly, lasting from 1 week to 2 years. Outcomes included treatment side effects, fatigue, sleep, quality of life, biomarkers (e.g., inflammatory markers), psychosocial factors, anxiety, and depression.

Conclusions

Although positive outcomes were reported in domains of quality of life and emotional well-being, null findings were reported for vasomotor symptoms such as hot flashes for breathing interventions. The wide range of interventions and outcomes administered to patients in various phases of the breast cancer care continuum complicates firm conclusions. Recruitment and adherence issues were noted in multiple studies. Future research should use more objective outcome measures, increase accessibility of the intervention (e.g., via telehealth) to improve adherence, and include longer follow-up periods to evaluate survival and recurrence.

背景:乳腺癌患者从最初的诊断到生存期间都经历着痛苦、治疗相关的不适和对复发的恐惧。目的本研究旨在评估呼气干预对乳腺癌患者和幸存者心理健康和生活质量的影响。方法我们检索了多个数据库中涉及呼吸法干预乳腺癌患者的随机对照试验。结果在筛选的5909项研究中,有16项研究涉及1726名受试者符合纳入标准。呼吸干预包括瑜伽(n = 9)、气功(n = 4)和其他呼吸技巧(n = 3)。我们发现,平均偏倚风险最高的是随机化过程,尽管纳入研究的总体偏倚总体较低,但由于未量化的家庭实践依从性,在准确评估偏离预期干预措施方面存在挑战。干预措施每天或每周进行,持续1周到2年。结果包括治疗副作用、疲劳、睡眠、生活质量、生物标志物(如炎症标志物)、社会心理因素、焦虑和抑郁。结论:尽管在生活质量和情绪健康方面报告了积极的结果,但呼吸干预对血管舒缩症状(如潮热)的影响为零。在乳腺癌护理连续体的不同阶段对患者进行的广泛干预和结果使确切的结论复杂化。在多项研究中注意到招募和依从性问题。未来的研究应使用更客观的结果测量,增加干预的可及性(例如,通过远程医疗)以提高依从性,并包括更长的随访期以评估生存和复发。
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引用次数: 0
TUG and Six-Minute Walk Test in Vietnamese Community-Dwelling Elderly 越南社区居住老年人的TUG和6分钟步行测试
Q3 Medicine Pub Date : 2025-07-04 DOI: 10.1002/lim2.70031
Luc Viet Tran, Thu Thi Hoai Nguyen, Hoa Trung Dinh, Thanh Xuan Nguyen, Tam Ngoc Nguyen, Huong Thi Thu Nguyen, Anh Lan Nguyen, Linh Vu Huyen Ha, Thang Pham, Anh Trung Nguyen, Huyen Thi Thanh Vu

Purpose

To apply the Time Up and Go test (TUG) and Six-Minute Walk test (6MWT) as tools to screen community-dwelling older people for fall risk in Vietnam.

Methods

This cross-sectional study was conducted among community-dwelling elders aged 60 and over living in Soc Son district, Vietnam. The TUG and 6MWT were used to assess the risk of falls. The protocol was approved by the National Geriatric Hospital Ethicsal Board (reference no. 35/2017), and all participants provided written informed consent in accordance with the Declaration of Helsinki.

Results

A total of 487 participants were included the mean age was 70.9 years (SD = 8.3). There were 67.1% of participants with a high risk of falling according to the TUG, and 5.1% lower than the limits of the norm with the 6MWT test. A statistically significant difference of the TUG was found in the variables of a fall during the past 12 months, fear of falling, narrow indoor path, and indoor light mobility barriers (p < 0.05).

Conclusions

A high prevalence of fall risk was observed among older adults residing in the community. The findings can be helpful in conducting further community-based studies in Vietnam.

目的应用Time Up and Go测试(TUG)和6分钟步行测试(6MWT)作为筛查越南社区老年人跌倒风险的工具。方法对越南Soc Son地区60岁及以上社区居住老年人进行横断面研究。使用TUG和6MWT来评估坠落风险。该议定书已得到国家老年医院伦理委员会的批准(参考号:35/2017),所有参与者根据赫尔辛基宣言提供书面知情同意。结果共纳入487例,平均年龄70.9岁(SD = 8.3)。根据TUG,有67.1%的参与者有较高的跌倒风险,比6MWT测试的标准限制低5.1%。在过去12个月内跌倒、害怕跌倒、狭窄的室内路径和室内光移动障碍等变量中,TUG差异有统计学意义(p <;0.05)。结论居住在社区的老年人存在较高的跌倒风险。这些发现有助于在越南进一步开展以社区为基础的研究。
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引用次数: 0
Domain-Specific Diabetes Self-Management Correlates of Quality of Life Among Adults With Diabetes Mellitus in Routine Care at a Tertiary Hospital in Ghana 特定领域糖尿病自我管理与加纳一家三级医院常规护理中糖尿病成人患者的生活质量相关
Q3 Medicine Pub Date : 2025-07-03 DOI: 10.1002/lim2.70032
Kwadwo Faka Gyan, Priscilla Abrafi Opare-Addo, Harris Osei-Mensah, Felix Andy Boateng, Isaac Nyanor, Kojo Awotwi Hutton-Mensah, Enoch Agyenim-Boateng, Elliot Koranteng Tannor

Introduction

Diabetes self-management practices may improve the quality of life of patients with diabetes mellitus. This study sought to explore the correlation between specific domains of self-management and quality of life in patients with diabetes.

Methods

This was a cross-sectional study involving 360 adults attending the diabetes clinic in a tertiary hospital in Kumasi, Ghana. Clinical variables were obtained through medical record review, and diabetes self-management practices and quality of life were assessed using standardized tools. A multivariable linear regression analysis between self-management and quality of life, followed by Pearson and Spearman correlation analysis between self-management domain scores and quality of life domain scores, was used to explore the relationship.

Results

The mean fasting blood sugar was 9.0 ± 4.8 mmol/L, with 40.8% having good glycaemic control. The mean quality of life score increases by 3.7 units for each unit increase in diabetes self-management score (coefficient = 3.7, 95% confidence interval = 2.95–4.50, p < 0.001). The diabetes self-management sum score correlated moderately with the total quality of life score (r = 0.385, p < 0.001). The strongest correlation of self-management with quality of life was observed in the physical activity domain (r = 0.473, p < 0.001) and the weakest in the glucose management domain (r = 0.181, p < 0.001). Glucose management correlated with the environment domain, dietary control with the psychological domain, physical activity with the physical health domain and healthcare use with the psychological domain of quality of life, respectively.

Conclusion

Improvement in diabetes self-management has a corresponding linear increase in quality of life in patients with diabetes. Self-management practices uniquely influence various domains of quality of life, highlighting the need for comprehensive self-management interventions in order to enhance the overall quality of life of patients with diabetes.

糖尿病自我管理实践可提高糖尿病患者的生活质量。本研究旨在探讨糖尿病患者自我管理的特定领域与生活质量之间的相关性。方法:这是一项横断面研究,涉及在加纳库马西一家三级医院糖尿病诊所就诊的360名成年人。通过病历回顾获得临床变量,并使用标准化工具评估糖尿病自我管理实践和生活质量。采用多变量线性回归分析自我管理与生活质量之间的关系,并采用Pearson和Spearman相关分析自我管理领域得分与生活质量领域得分之间的关系。结果患者平均空腹血糖9.0±4.8 mmol/L,其中40.8%血糖控制良好。糖尿病自我管理评分每增加1个单位,平均生活质量评分增加3.7个单位(系数= 3.7,95%可信区间= 2.95-4.50,p <;0.001)。糖尿病自我管理总分与生活质量总分有中度相关(r = 0.385, p <;0.001)。自我管理与生活质量的相关性在体育活动领域最为显著(r = 0.473, p <;0.001),葡萄糖管理区最弱(r = 0.181, p <;0.001)。葡萄糖管理与环境领域相关,饮食控制与心理领域相关,身体活动与身体健康领域相关,医疗保健使用与生活质量的心理领域相关。结论糖尿病患者自我管理水平的提高对生活质量有相应的线性提高。自我管理实践独特地影响生活质量的各个领域,强调需要全面的自我管理干预措施,以提高糖尿病患者的整体生活质量。
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引用次数: 0
Higher Saliva pH Among Vegetarians Compared With Nonvegetarians in Hong Kong 香港素食者唾液pH值高于非素食者
Q3 Medicine Pub Date : 2025-06-30 DOI: 10.1002/lim2.70030
Princess-Lisa Cofie, Hildemar Dos Santos, Josileide Gaio, Alicia Carranza, Wenes P. Reis, Peter Chuk

Introduction

An optimal salivary pH level above 5.5 is crucial for maintaining oral health and preventing tooth decay. Furthermore, oral health may correlate with a reduced risk of chronic conditions such as diabetes and heart disease. This cross-sectional study aims to compare the differences in salivary pH levels between vegetarians and nonvegetarians.

Methods

During a vegetarian health festival in Hong Kong, we invited participants to complete a health questionnaire and measure their saliva pH 30 min after meals. Approximately 237 individuals volunteered for the study, consisting of 79 vegetarians and 158 nonvegetarians.

Results

An Independent Samples t-test showed that vegetarians exhibited a pH of 7.07, whereas nonvegetarians had a pH of 6.61 (p < 0.001). The contrasting dietary patterns between the two groups indicated that vegetarians consumed a higher quantity of beans and nuts, while nonvegetarians favored meats and beverages such as coffee, sodas, and juices. In a distinct analysis independent of dietary categorization, foods linked with a higher pH level included beans and vegetables.

Conclusion

A higher saliva pH was observed in vegetarians compared to nonvegetarians. The primary component of the vegetarian diet potentially accounting for this difference is beans, which were found to be independently associated with elevated pH levels in our study. Furthermore, vegetables were also identified as foods contributing to this increase in pH. However, further experimental and longitudinal studies are required to validate these findings.

唾液pH值在5.5以上对维持口腔健康和预防蛀牙至关重要。此外,口腔健康可能与降低慢性疾病(如糖尿病和心脏病)的风险有关。这项横断面研究旨在比较素食者和非素食者唾液pH值的差异。方法在香港素食健康节期间,我们邀请参与者完成一份健康问卷,并测量他们饭后30分钟的唾液pH值。大约有237人自愿参加这项研究,其中包括79名素食者和158名非素食者。结果独立样本t检验显示,素食者的pH值为7.07,而非素食者的pH值为6.61 (p <;0.001)。两组之间的饮食模式对比表明,素食者消耗更多的豆类和坚果,而非素食者更喜欢肉类和饮料,如咖啡、苏打水和果汁。在一项独立于饮食分类的独特分析中,与较高pH值相关的食物包括豆类和蔬菜。结论素食者唾液pH值高于非素食者。素食饮食的主要成分可能是豆类,在我们的研究中,豆类被发现与pH值升高独立相关。此外,蔬菜也被认为是导致ph值增加的食物。然而,需要进一步的实验和纵向研究来验证这些发现。
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引用次数: 0
Knowledge, Attitude, Practice and Barriers of Exercise Among Postpartum Women in a Low-Resource Setting 低资源环境下产后妇女运动的知识、态度、行为和障碍
Q3 Medicine Pub Date : 2025-06-13 DOI: 10.1002/lim2.70028
Dorothy Ekua Adjabu, Jonathan Quartey, Tawagidu Mohammed, Mubarak Abdul-Rahman, Diphale Joyce Mothabeng

Introduction

Physical inactivity predisposes mothers to untoward physical and mental health outcomes. Acquiring requisite knowledge pertaining to postpartum exercise promotes a good attitude and facilitates participation in exercises in spite of the presence of barriers. This study aimed to determine the knowledge, attitude, practice and barriers to postpartum exercises among women within 6 weeks to 1 year after childbirth.

Methods

This is a quantitative, cross-sectional study involving 146 postpartum women at a tertiary hospital in Accra, Ghana. Respondents completed an adapted survey tool–Knowledge, attitude and practice of postpartum exercise. The Statistical Package for Social Sciences (SPSS) 27 was used to perform all analyses using descriptive and inferential statistics with significance at a p-value of 0.05.

Results

Sixty-five percent reported a low general knowledge of postpartum exercise, 63% had an average knowledge of the benefits of exercise whilst 94% had a high knowledge of contraindications of exercise. Eighty-four percent of the respondents revealed a good attitude, although only 36% participated in postpartum exercises. Fifty-two percent of the postpartum women indicated that lack of time was a barrier for them, whilst 42% reported that lack of information was a barrier. Significant associations were discovered between general knowledge of postpartum exercise and practice (𝛘2 = 14.157, p-value = 0.001) as well as attitude and barriers (𝛘2 = 9.114, p-value = 0.003).

Conclusion

This study highlights a low knowledge and practice of exercise among postpartum women at a single tertiary centre in Ghana, although they exhibit a good attitude towards exercise amidst major barriers. Findings suggest that health professionals in maternal healthcare should provide information regarding postpartum exercises as an essential aspect of postpartum care plans in low-resource settings to promote health outcomes.

缺乏身体活动使母亲容易产生不利的身心健康结果。获得有关产后锻炼的必要知识可以促进良好的态度,并促进参与锻炼,尽管存在障碍。本研究旨在了解妇女产后6周至1年内对产后运动的知识、态度、行为和障碍。方法:这是一项定量的横断面研究,涉及加纳阿克拉一家三级医院的146名产后妇女。受访者完成了一项适应性的调查工具-产后运动的知识、态度和实践。使用社会科学统计软件包(SPSS) 27进行所有分析,使用描述性和推理统计,p值为0.05。结果65%的人对产后运动的一般知识较低,63%的人对运动的好处有一般的了解,94%的人对运动的禁忌症有很高的了解。84%的受访者表现出良好的态度,尽管只有36%的人参加了产后锻炼。52%的产后妇女表示,缺乏时间是一个障碍,而42%的人报告说,缺乏信息是一个障碍。产后运动的一般知识和实践(𝛘2 = 14.157,p值= 0.001)与态度和障碍(𝛘2 = 9.114,p值= 0.003)之间存在显著相关性。本研究强调了加纳单一三级中心的产后妇女对运动的认识和实践较低,尽管她们在主要障碍中表现出良好的运动态度。研究结果表明,在低资源环境下,孕产妇保健专业人员应提供有关产后锻炼的信息,作为产后护理计划的一个重要方面,以促进健康结果。
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引用次数: 0
An Exploratory Study Into the Effects of Regular Cold-Water Sea Swimming on Daily Indices of Mental Health 定期冷水海水游泳对心理健康日常指标影响的探索性研究
Q3 Medicine Pub Date : 2025-06-13 DOI: 10.1002/lim2.70029
Jill Forsten, Mark A. Wetherell

Aims

There is an emerging literature demonstrating the physical and psychological benefits of cold-water swimming. The majority of this research, however, is qualitative or assesses effects across several months. As daily changes in mood contribute to overall well-being, the current study sought to explore more proximal changes by adopting a diary approach to investigate the effects of regular cold-water swimming.

Methods

Data were collected from an opportunistic sample of healthy, regular, female swimmers (N = 13) in the United Kingdom. Participants completed online questionnaires twice daily. They reported whether it was a swim day or a non-swim day and then completed questions assessing state, cognitive and somatic anxiety, self-confidence (morning and evening) and feelings of wellness and sleep quality the night before (morning only). Analysis of variance was conducted to assess differences between swim and non-swim days.

Results

Cold-water swimming led to significant reductions in anxiety and increases in self-confidence on the day of a swim and improved self-reported sleep and lower levels of next-morning anxiety.

Conclusions

This exploratory study is the first to utilise a daily diary method to capture proximal changes in regular cold-water swimmers. These results provide further evidence of the beneficial effects of cold-water swimming on factors that contribute to psychological well-being.

目的越来越多的文献证明了冷水游泳对身体和心理的好处。然而,大多数研究都是定性的,或者评估几个月的效果。由于情绪的日常变化有助于整体健康,目前的研究试图通过采用日记的方法来探索更多的近距离变化,以调查定期冷水游泳的影响。方法从英国健康、经常游泳的女性(N = 13)的机会性样本中收集数据。参与者每天完成两次在线问卷。他们报告当天是游泳日还是不游泳日,然后完成评估状态、认知和躯体焦虑、自信(早上和晚上)、健康感觉和前一天晚上的睡眠质量的问题(只在早上)。进行方差分析以评估游泳和非游泳天数之间的差异。结果:冷水游泳显著减少了游泳当天的焦虑,增强了自信,改善了自我报告的睡眠,降低了第二天早上的焦虑水平。结论:这项探索性研究首次利用每日日记法捕捉常规冷水游泳者近端变化。这些结果进一步证明了冷水游泳对心理健康的有益影响。
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引用次数: 0
The Correlation of Work-Related Stress, Sleep Quality, and Physical Activity Among Academic Staff in a Nigerian Medical School: A Cross-Sectional Study 尼日利亚一所医学院学术人员工作压力、睡眠质量和身体活动的相关性:一项横断面研究
Q3 Medicine Pub Date : 2025-05-24 DOI: 10.1002/lim2.70027
Uzoamaka Nwakaego Akobundu, Sochima Johnmark Obiekwe, Jennifer Ezeigwe, Amaechi Ifeoma Adaigwe, Uchenna Prosper Okonkwo, Ada Jovita Daniel, Christopher Olusanjo Akosile

Background

The interrelationship of stress and sleep disorders has long been established with physical activity (PA) proven effective in their management. Academic staff in medical schools may face heightened stress levels when compared with staff in other disciplines as a result of the rigorous academic environment in medical schools, in addition to other possible work stressors. This study aimed to investigate the levels of stress, sleep disorders, and PA among academic staff at the medical school of Nnamdi Azikiwe University, Awka, Nigeria, and to determine the relationship between these variables.

Methods

This cross-sectional study consecutively recruited 92 adult lecturers at the study site. Data were collected using the Short Form of International Physical Activity Questionnaire (IPAQ-SF), Pittsburgh Quality of Sleep Index (PSQI), and the Health and Safety Work-Related Stress Questionnaire. Data were analyzed using the Statistical Package for Social Sciences (SPSS) version 26. The Spearman's rank correlation coefficient was used to assess the association between variables at a significance level of 0.05.

Results

The mean age of the participants was 40.00 ± 7.34 years. The mean score for work-related stress, sleep quality, and PA was 66.09 ± 6.58, 7.84 ± 3.48 (poor quality), and 1219.34 ± 827.83 (moderate PA), respectively. There was a significant positive correlation between work-related stress and PA levels (ρ = 0.22, p = 0.03). Also, there was no significant correlation between sleep quality and work-related stress (ρ = −0.16, p = 0.11) and between work-related stress and sleep quality (ρ = 0.19, p = 0.06).

Conclusion

In conclusion, high concerns of work stress, poor sleep quality, and moderate PA were observed among the study participants. Targeted interventions to promote PA, improve sleep hygiene practices, and alleviate work-related stress among academic staff are recommended.

应激与睡眠障碍之间的相互关系早已被确立,体育活动(PA)已被证明是有效的治疗方法。除了其他可能的工作压力因素外,医学院的学术人员与其他学科的工作人员相比,可能面临更大的压力。本研究旨在调查尼日利亚Awka Nnamdi Azikiwe大学医学院学术人员的压力、睡眠障碍和PA水平,并确定这些变量之间的关系。方法本横断面研究在研究现场连续招募92名成人讲师。数据采用国际体育活动简易问卷(IPAQ-SF)、匹兹堡睡眠质量指数(PSQI)和健康与安全工作相关压力问卷收集。数据分析使用社会科学统计软件包(SPSS)版本26。采用Spearman等级相关系数评价变量间的相关性,显著性水平为0.05。结果患者平均年龄40.00±7.34岁。工作压力、睡眠质量、睡眠质量的平均得分分别为66.09±6.58分(差)、7.84±3.48分(中)、1219.34±827.83分(中)。工作压力与PA水平呈显著正相关(ρ = 0.22, p = 0.03)。此外,睡眠质量与工作压力之间无显著相关性(ρ = - 0.16, p = 0.11),工作压力与睡眠质量之间无显著相关性(ρ = 0.19, p = 0.06)。结论研究对象对工作压力的关注程度较高,睡眠质量较差,PA程度中等。建议有针对性的干预措施,以促进PA,改善睡眠卫生习惯,减轻学术人员的工作压力。
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引用次数: 0
Understanding Gender Disparities in Quality of Life Among Patients With Type 2 Diabetes in Ethiopia: An Institutional-Based Study 了解埃塞俄比亚2型糖尿病患者生活质量的性别差异:一项基于机构的研究
Q3 Medicine Pub Date : 2025-05-04 DOI: 10.1002/lim2.70025
Enguday Demeke Gebeyaw, Girma Deshimo Lema

Introduction

Health-related quality of life (HRQoL) is a multidimensional concept that reflects an individual's perception of their overall health. In Ethiopia, research on diabetes has generally focused on the clinical aspects of the disease, such as glucose control, medication, and complications. However, social factors like gender have not been given a focus. This study aimed to assess gender differences in HRQoL and identify gender-specific factors contributing to poor HRQoL.

Research Design and Methods

A cross-sectional study was conducted among 380 type 2 diabetes mellitus patients (190 males and 190 females) at Debre Berhan public hospitals from January 1 to March 30, 2024. HRQoL was measured using the revised version diabetic-specific quality of life questionnaire (RV-DQoL13) scale. Chi-squared tests were utilized to analyze gender differences in HRQoL, while logistic regression was employed to identify gender-specific factors influencing HRQoL. A significant association was declared at a p-value less than 0.05.

Results

Female patients reported significantly poorer HRQoL than their male counterparts. From HRQoL domains, women reported higher levels of worry and lower satisfaction scores, whereas men had higher impact scores. Among males, factors associated with poor HRQoL included age > 60 years, lower educational status, and diabetes complications, whereas being privately employed was related to better HRQoL. For females, lower educational status, duration of diabetes > 5 years and diabetes complications were significant determinants of poor HRQoL, while being married and having a normal body mass index were associated with better HRQoL.

Conclusion

Gender differences in HRQoL among type 2 diabetes patients at Debre Berhan public hospitals are influenced by a complex interplay of sociodemographic, behavioral, and clinical variables. The study highlights the need for considering both gender-specific and general factors when assessing HRQoL. Healthcare professionals may need to adopt gender-sensitive healthcare practices to address the unique needs of men and women.

与健康有关的生活质量(HRQoL)是一个多维概念,反映了个人对其整体健康状况的看法。在埃塞俄比亚,对糖尿病的研究一般集中在该疾病的临床方面,如血糖控制、药物治疗和并发症。然而,性别等社会因素并没有得到重视。本研究旨在评估HRQoL的性别差异,并确定导致HRQoL差的性别特定因素。研究设计与方法对2024年1月1日至3月30日在Debre Berhan公立医院就诊的380例2型糖尿病患者(男190例,女190例)进行横断面研究。HRQoL采用修订版糖尿病特异性生活质量问卷(RV-DQoL13)量表进行测量。采用卡方检验分析HRQoL的性别差异,采用logistic回归分析HRQoL的性别影响因素。p值小于0.05时,有显著相关性。结果女性患者的HRQoL明显低于男性患者。从HRQoL领域来看,女性的忧虑程度较高,满意度得分较低,而男性的影响得分较高。在男性中,与HRQoL差相关的因素包括年龄;60岁,教育程度低,糖尿病并发症,而私营企业与较好的HRQoL相关。女性受教育程度低、糖尿病持续时间长;5岁和糖尿病并发症是较差HRQoL的重要决定因素,而已婚和正常体重指数与较好的HRQoL相关。结论Debre Berhan公立医院2型糖尿病患者HRQoL的性别差异受社会人口学、行为和临床变量复杂的相互作用影响。该研究强调,在评估HRQoL时,需要同时考虑特定性别和一般因素。保健专业人员可能需要采取对性别问题敏感的保健做法,以解决男子和妇女的独特需求。
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引用次数: 0
The ASSIST Trial: Acute Effects of Manipulating Strength Exercise Volume on Insulin Sensitivity in Adults Living With Obesity: A Randomized Controlled, Crossover, Clinical Trial ASSIST试验:调节力量运动量对肥胖成人胰岛素敏感性的急性影响:一项随机对照、交叉临床试验
Q3 Medicine Pub Date : 2025-04-30 DOI: 10.1002/lim2.70024
Luis Filipe Rocha Silva, Paulo H. Evangelista Silva, Jordan Ottoni do Carmo, Bruna Caroline Chaves Garcia, Elizabethe Adriana Esteves, Zachary Aaron Mang, Fabiano Trigueiro Amorim, Marco Fabrício Dias-Peixoto, Fernando Gripp, Valmor Tricoli, Flavio de Castro Magalhaes

Aims

To investigate the influence of exercise volume on the transient increase in insulin sensitivity and β-cell function that occurs in the hours following an acute bout of strength exercise.

Materials and methods

Fifteen (14 females) adults living with obesity (47.4 ± 9.7 years, 44.3 ± 4.1% body fat) performed three randomized sessions separated by at least four washout days: (1) high volume (21 sets); (2) low volume (7 sets), and (3) control. An oral glucose tolerance test (OGTT) was performed the following morning, and indexes of insulin sensitivity and β-cell function were calculated using glucose, insulin, and C-peptide assessed during the OGTT. Every participant completed each arm of the experiment and was included in the data analysis (n = 15). Researchers who conducted data and statistical analysis were blinded to individuals and sessions.

Results

One-way repeated measure analysis of variance followed by Tukey as post hoc showed that indexes of insulin sensitivity improved after the high-volume session (p < 0.05) but not after the low-volume session (p > 0.05) (effect size [EF] for high and low volume, respectively): insulin area under the curve (AUC) [−0.53 and −0.05], C-peptide AUC [0.58 and 0.18], Cederholm index [0.59 and 0.11], skeletal muscle index [0.89 and 0.60], Gutt index [0.78 and 0.20], Stumvoll index [0.81 and 0.18], and the simple index [0.52 and 0.16]). β-cell function showed a strong tendency to improve (p < 0.06) after the high-volume session (EF for high and low volume, respectively): C-peptidogenic index [0.58 and −0.20], C-peptide oral disposition index [0.72, −0.33]. No adverse effects were observed during data collection.

Conclusions

These results suggest that adults living with obesity who are seeking to improve insulin sensitivity should perform high-volume strength exercises.

目的探讨运动量对急性力量运动后数小时内胰岛素敏感性和β细胞功能短暂性升高的影响。材料与方法15名(14名女性)肥胖成人(47.4±9.7岁,体脂44.3±4.1%)随机分为3组,间隔至少4天洗脱期:(1)高容量(21组);(2)低音量(7套),(3)控制。次日上午进行口服葡萄糖耐量试验(OGTT),并在OGTT中测定葡萄糖、胰岛素和c肽,计算胰岛素敏感性和β细胞功能指标。每个参与者完成实验的每一组,并被纳入数据分析(n = 15)。进行数据和统计分析的研究人员对个人和会议是盲目的。结果单因素重复测量方差分析(事后Tukey分析)显示,高剂量治疗后胰岛素敏感性指标有所改善(p <;0.05),但在低音量会话后没有(p >;0.05)(分别为高、低体积效应量[EF]):胰岛素曲线下面积(AUC)[- 0.53和- 0.05]、c肽AUC[0.58和0.18]、Cederholm指数[0.59和0.11]、骨骼肌指数[0.89和0.60]、Gutt指数[0.78和0.20]、Stumvoll指数[0.81和0.18]、simple指数[0.52和0.16])。β-细胞功能有明显改善的趋势(p <;0.06)(高、低容量分别为EF): c肽原指数[0.58和- 0.20],c肽口服处置指数[0.72,- 0.33]。在数据收集过程中未观察到不良反应。结论:这些结果表明,寻求改善胰岛素敏感性的肥胖成年人应该进行大容量的力量锻炼。
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引用次数: 0
Impact of COVID-19 on Mental Health: Post-Traumatic Stress and Coping Strategies Among Thai University Students Using Ordinal Logistic Regression Analysis 新冠肺炎对心理健康的影响:泰国大学生创伤后应激及应对策略
Q3 Medicine Pub Date : 2025-04-30 DOI: 10.1002/lim2.70023
Peeradech Thichanpiang, Anuchart Kaunnil, Pornlada Nuchnoi, Chutikorn Nopparat, Khanokporn Donjdee, Kannika Permpoonputtana

Aims

COVID-19 disrupted education globally, resulting in the closure of schools and universities and the transition to distance learning. This shift heightened concerns about contracting the virus and increased insecurity in daily life and online education. The primary objective of this study is to investigate post-traumatic stress, perceived stress, coping strategies, and quality of life (QOL) among Thai university students, while also examining the relationships among coping strategies, stress levels, mental illness history, and overall QOL.

Methods

This study utilized a cross-sectional survey method, engaging 400 students through an online self-reported survey. The survey instruments included the post-traumatic stress disorder (PTSD) checklist for DSM-5, the Thai Version of the Perceived Stress Scale, the Brief Coping Orientation to Problems Experienced Inventory, and the WHOQOL Instrument-Short Form.

Results

The study found that 21.25% of Thai university students likely experienced PTSD during the pandemic, with 74% reporting moderate stress and 4.25% experiencing high stress. Common coping strategies included acceptance, planning, active coping, self-distraction, and positive reframing, whereas self-blame was more prevalent among students with higher stress levels. QOL assessments showed that 2.75% of students rated their QOL as poor, 55.75% as moderate, and 41.50% as good. A strong negative correlation was observed between QOL and stress levels, indicating that students with lower QOL experienced higher stress. Additionally, maladaptive coping strategies, such as self-blame, denial, and behavioral disengagement, were positively associated with increased stress. Ordinal logistic regression analysis identified QOL as a significant predictor of perceived stress levels (odds ratios [OR] = 3.607), accounting for 31% of the variability in stress levels.

Conclusions

Students with poorer QOL experienced higher stress levels, underscoring the need for enhanced psychosocial services to support their mental health and overall well-being.

2019冠状病毒病扰乱了全球的教育,导致学校和大学关闭,并向远程教育过渡。这种转变加剧了人们对感染病毒的担忧,增加了日常生活和在线教育的不安全感。摘要本研究旨在探讨泰国大学生的创伤后应激、感知应激、应对策略与生活质量(QOL),以及应对策略、压力水平、精神病史与总体生活质量之间的关系。方法本研究采用横断面调查法,对400名学生进行在线自我报告调查。调查工具包括DSM-5的创伤后应激障碍(PTSD)检查表、泰文压力感知量表、问题经历的简短应对倾向量表和WHOQOL工具-简表。研究发现,21.25%的泰国大学生可能在疫情期间经历过创伤后应激障碍,74%的大学生报告有中度压力,4.25%的大学生报告有高度压力。常见的应对策略包括接受、计划、积极应对、自我分散和积极重构,而自责在压力水平较高的学生中更为普遍。生活质量评估显示,2.75%的学生认为自己的生活质量差,55.75%的学生认为自己的生活质量一般,41.50%的学生认为自己的生活质量好。生活质量与压力水平呈显著负相关,表明生活质量越低的学生压力越大。此外,适应不良的应对策略,如自责、否认和行为脱离,与压力增加呈正相关。有序逻辑回归分析发现,生活质量是感知压力水平的显著预测因子(比值比[OR] = 3.607),占压力水平变异性的31%。结论:生活质量较差的学生压力水平较高,强调需要加强心理社会服务,以支持他们的心理健康和整体福祉。
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引用次数: 0
期刊
Lifestyle medicine (Hoboken, N.J.)
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