Zoltán Horváth, Attila Paszt, Zsolt Simonka, Melinda Látos, László Kaizer, Sándor Hamar, András Vörös, Katalin Ormándi, Zsuzsanna Fejes, Judit Oláh, György Lázár
Oncosurgical treatment of breast tumors involves the removal of metastatic axillary lymph nodes. In the last 30 years, the diagnosis and treatment of axillary lymph nodes have also undergone significant changes. The introduction of sentinel lymph node biopsy in 1993 made axillary block dissection with high morbidity safely omitted in a significant proportion of patients, and similarly, the staging of breast tumors and thus oncology and complex treatment became significantly more accurate. Shortly after the introduction of sentinel lymph node biopsy, intraoperative examination of sentinel lymph nodes (e.g. imprint cytology) also appeared, which significantly reduced the number of surgeries performed in the two sessions, thereby significantly reducing patient burden and surgical costs. The results of our study indicate that axillary block dissection is required in the treatment of axilla in an ever-decreasing group of patients and this proportion will decrease further in the future, with the increasing use of alternative axillary radiotherapy. The imprint cytological examination of sentinel lymph nodes taking into account current guidelines, no longer provides demonstrable benefits and its routine use is not justified. According to the latest international recommendations, intraoperative examination of the sentinel lymph node may be indicated in connection with mastectomy (when postoperative radiotherapy is not planned) and after neoadjuvant treatment. Our results suggest that the detection of suspected lymph nodes during preoperative axillary ultrasound may predict the stage of the disease. Based on our research results confirm that in patients receiving neoadjuvant therapy, in addition to the preoperative size of the tumour (≤20 mm, P = 0.002), the preoperative size of the lymph node (≤15 mm, P = 0.04) may also be used to predict that the stage of the disease is N0-1.
乳腺肿瘤的肿瘤外科治疗包括转移性腋窝淋巴结的切除。近30年来,腋窝淋巴结的诊断和治疗也发生了重大变化。1993年前哨淋巴结活检的引入,使得相当一部分患者安全地省去了高发病率的腋窝块清扫,同样,乳腺癌的分期以及肿瘤和复杂治疗也明显更加准确。前哨淋巴结活检引入后不久,术中也出现了前哨淋巴结检查(如印记细胞学),这大大减少了两会的手术数量,从而大大减轻了患者负担和手术费用。我们的研究结果表明,在治疗腋窝的患者中,需要腋窝块解剖的患者越来越少,并且随着替代腋窝放疗的使用增加,这一比例将进一步降低。前哨淋巴结的印迹细胞学检查考虑到目前的指导方针,不再提供明显的好处,其常规使用是不合理的。根据最新的国际建议,术中检查前哨淋巴结可能与乳房切除术(术后不计划放疗)和新辅助治疗有关。我们的研究结果表明,术前腋窝超声检测可疑淋巴结可以预测疾病的分期。根据我们的研究结果证实,在接受新辅助治疗的患者中,除了术前肿瘤大小(≤20mm, P = 0.002)外,术前淋巴结大小(≤15mm, P = 0.04)也可用于预测疾病分期为0-1期。
{"title":"New trends in the surgical treatment of axilla in breast cancer","authors":"Zoltán Horváth, Attila Paszt, Zsolt Simonka, Melinda Látos, László Kaizer, Sándor Hamar, András Vörös, Katalin Ormándi, Zsuzsanna Fejes, Judit Oláh, György Lázár","doi":"10.1556/1046.2022.20012","DOIUrl":"https://doi.org/10.1556/1046.2022.20012","url":null,"abstract":"<p><p>Oncosurgical treatment of breast tumors involves the removal of metastatic axillary lymph nodes. In the last 30 years, the diagnosis and treatment of axillary lymph nodes have also undergone significant changes. The introduction of sentinel lymph node biopsy in 1993 made axillary block dissection with high morbidity safely omitted in a significant proportion of patients, and similarly, the staging of breast tumors and thus oncology and complex treatment became significantly more accurate. Shortly after the introduction of sentinel lymph node biopsy, intraoperative examination of sentinel lymph nodes (e.g. imprint cytology) also appeared, which significantly reduced the number of surgeries performed in the two sessions, thereby significantly reducing patient burden and surgical costs. The results of our study indicate that axillary block dissection is required in the treatment of axilla in an ever-decreasing group of patients and this proportion will decrease further in the future, with the increasing use of alternative axillary radiotherapy. The imprint cytological examination of sentinel lymph nodes taking into account current guidelines, no longer provides demonstrable benefits and its routine use is not justified. According to the latest international recommendations, intraoperative examination of the sentinel lymph node may be indicated in connection with mastectomy (when postoperative radiotherapy is not planned) and after neoadjuvant treatment. Our results suggest that the detection of suspected lymph nodes during preoperative axillary ultrasound may predict the stage of the disease. Based on our research results confirm that in patients receiving neoadjuvant therapy, in addition to the preoperative size of the tumour (≤20 mm, P = 0.002), the preoperative size of the lymph node (≤15 mm, P = 0.04) may also be used to predict that the stage of the disease is N0-1.</p>","PeriodicalId":74097,"journal":{"name":"Magyar sebeszet","volume":"75 2","pages":"169-178"},"PeriodicalIF":0.0,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10380336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Száz éves a Szegedi Tudományegyetem Sebészeti Klinikája - Köszöntő.","authors":"György Lázár","doi":"10.1556/1046.2022.20003","DOIUrl":"https://doi.org/10.1556/1046.2022.20003","url":null,"abstract":"","PeriodicalId":74097,"journal":{"name":"Magyar sebeszet","volume":"75 2","pages":"103"},"PeriodicalIF":0.0,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10827343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zsolt Palásthy, Róbert Sipka, Gábor Mihalovits, Tibor Takács, László Leindler, Zoltán Hódi, Rita Váradi, Áron Nyilas, Endre Nagy, András Nagy, Andrea Vass, Zoltán Ruzsa, Gábor Bogáts, György Lázár
Introduction and aims. In recent decades health care changes have accelerated enormously. Previously, by learning an effective procedure, the doctor could guarantee his patients the highest level of care for many years. Nowadays, due to the dynamics of development, the renewal cycles of the methods have been shortened, without continuous learning and training, it is already inconceivable to provide the up-to-date care required by patients. Patients and methods. Instead of vascular replacements with prosthetic grafts, which played an important role in vascular reconstructions, the primacy of endovascular techniques has become decisive. It can be significant for aortic aneurysms that can be operated with high invasiveness. The learning of catheter techniques by vascular surgeons made it possible to treat more successfully those limb-threatening cases, which are often associated with extensive vascular involvement, through the so-called hybrid operations. In addition to the increasing prevalence of diabetes worldwide, the higher proportion of critical limb ischemia and the highlighted pathogenic role of multi-resistant bacteria in the disease caused the marginaliation of the use of previously preferred prosthetic grafts. The effectiveness of the treatment of graft infections, which thus become less frequent, is improved by the use of homografts and negative pressure therapy. An effective method of preventing stroke is carotid endarterectomy, the morbidity of which is reduced by the introduction of locoregional anaesthesia allowing direct neuromonitoring. Results/conclusions. Although the acquisition and implementation of new methods has posed a continuous challenge for our specialists and doctors over the past 10 years, our achievements have made our department one of the leading vascular surgery centres in the country.
{"title":"Changes in the care of peripheral vascular disease at the University of Szeged","authors":"Zsolt Palásthy, Róbert Sipka, Gábor Mihalovits, Tibor Takács, László Leindler, Zoltán Hódi, Rita Váradi, Áron Nyilas, Endre Nagy, András Nagy, Andrea Vass, Zoltán Ruzsa, Gábor Bogáts, György Lázár","doi":"10.1556/1046.2022.20015","DOIUrl":"https://doi.org/10.1556/1046.2022.20015","url":null,"abstract":"<p><p>Introduction and aims. In recent decades health care changes have accelerated enormously. Previously, by learning an effective procedure, the doctor could guarantee his patients the highest level of care for many years. Nowadays, due to the dynamics of development, the renewal cycles of the methods have been shortened, without continuous learning and training, it is already inconceivable to provide the up-to-date care required by patients. Patients and methods. Instead of vascular replacements with prosthetic grafts, which played an important role in vascular reconstructions, the primacy of endovascular techniques has become decisive. It can be significant for aortic aneurysms that can be operated with high invasiveness. The learning of catheter techniques by vascular surgeons made it possible to treat more successfully those limb-threatening cases, which are often associated with extensive vascular involvement, through the so-called hybrid operations. In addition to the increasing prevalence of diabetes worldwide, the higher proportion of critical limb ischemia and the highlighted pathogenic role of multi-resistant bacteria in the disease caused the marginaliation of the use of previously preferred prosthetic grafts. The effectiveness of the treatment of graft infections, which thus become less frequent, is improved by the use of homografts and negative pressure therapy. An effective method of preventing stroke is carotid endarterectomy, the morbidity of which is reduced by the introduction of locoregional anaesthesia allowing direct neuromonitoring. Results/conclusions. Although the acquisition and implementation of new methods has posed a continuous challenge for our specialists and doctors over the past 10 years, our achievements have made our department one of the leading vascular surgery centres in the country.</p>","PeriodicalId":74097,"journal":{"name":"Magyar sebeszet","volume":"75 2","pages":"185-193"},"PeriodicalIF":0.0,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10377231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aurél Ottlakán, Attila Paszt, Zsolt Simonka, Szabolcs Ábrahám, Csenge Vass, Krisztina Varga, Bernadett Borda, Márton Vas, Ádám Balogh, György Lázár
Aim. Our goal was to evaluate operative and perioperative data of retroperitoneal (RP) and transperitoneal (TP) adrenalectomies performed at the University of Szeged Department of Surgery. Patients and method. During a retrospective cohort study including 174 adrenalectomies (28 RP; 146 TP) performed between 1998 and 2021, the following parameters were evaluated: rate of previous abdominal surgeries, conversion rate, operative time, intraoperative blood loss, tumor size, histology, hospital stay, early and late complications. Results. With significantly higher rate of previous abdominal surgeries [TP vs RP: 68 (46.57%) vs 4 (14%) P = 0.0021], there was no markable difference in conversion rate [TP vs RP: 7 (4.79%) vs 5 (18%), P = 0.312]. Significantly larger tumours were removed with TP (TP vs RP: 58.05 vs 34.8 mm, P = 0.016), with no markable difference in intraoperative blood loss (TP vs RP: 67.85 vs 50.2 ml, P = 0.157). Operative time was significantly shorter in TP (TP vs RP: 86.3 vs 134.5 min; P = 0.024). The most frequent histology was adenoma (TP vs RP: n = 95; 65.06% vs 64.3%). Pheochromocytoma occurred in 11 (7.53%) and 5 (17.8%) cases in TP and RP, respectively. We found no significant difference in hospital stay (TP vs RP: 5.125 vs 4.61 day; P = 0.413). Five- and 2 cases of early complications were seen in TP (splenic injury, postoperative fever, severe intraoperative bleeding, severe hypokalemia, surgical site infection) and RP (2 severe intraoperative bleeding), respectively. One lethal case of ventricular fibrillation and one delayed complication (postoperative abdominal wall hernia) were observed in TP. Conclusions. Both TP and RP are safe and simply reproducible minimally invasive techniques. According to our observation, RP adrenalectomy seems to be reserved for smaller lesions, while TP proves to be successful in removing enlarged and also malignant lesions with significantly shorter operative time.
的目标。我们的目的是评估在塞格德大学外科进行的腹膜后(RP)和腹膜后(TP)肾上腺切除术的手术和围手术期数据。患者和方法。在一项包括174例肾上腺切除术(28例RP;我们评估了1998年至2021年间进行腹部手术的患者的以下参数:既往腹部手术率、转换率、手术时间、术中出血量、肿瘤大小、组织学、住院时间、早期和晚期并发症。结果。既往腹部手术率较高[TP vs RP: 68 (46.57%) vs 4 (14%) P = 0.0021],转换率无显著差异[TP vs RP: 7 (4.79%) vs 5 (18%), P = 0.312]。TP组切除较大的肿瘤(TP vs RP: 58.05 vs 34.8 mm, P = 0.016),术中出血量无显著差异(TP vs RP: 67.85 vs 50.2 ml, P = 0.157)。TP组手术时间明显缩短(TP vs RP: 86.3 vs 134.5 min;P = 0.024)。最常见的组织学为腺瘤(TP vs RP: n = 95;65.06% vs 64.3%)。TP和RP分别发生嗜铬细胞瘤11例(7.53%)和5例(17.8%)。我们发现住院时间无显著差异(TP vs RP: 5.125 vs 4.61天;P = 0.413)。TP组早期并发症(脾损伤、术后发热、术中大出血、严重低血钾、手术部位感染)5例,RP组早期并发症(术中大出血2例)2例。本组观察到1例心室颤动致死,1例迟发性并发症(术后腹壁疝)。结论。TP和RP都是安全且可简单复制的微创技术。根据我们的观察,RP肾上腺切除术似乎只适用于较小的病变,而TP可以成功切除肿大和恶性病变,且手术时间明显缩短。
{"title":"Minimally invasive adrenalectomy – Operative and perioperative results of transperitoneal and retroperitoneal adrenalectomies performed at the University of Szeged Department of Surgery during 23 years","authors":"Aurél Ottlakán, Attila Paszt, Zsolt Simonka, Szabolcs Ábrahám, Csenge Vass, Krisztina Varga, Bernadett Borda, Márton Vas, Ádám Balogh, György Lázár","doi":"10.1556/1046.2022.20016","DOIUrl":"https://doi.org/10.1556/1046.2022.20016","url":null,"abstract":"<p><p>Aim. Our goal was to evaluate operative and perioperative data of retroperitoneal (RP) and transperitoneal (TP) adrenalectomies performed at the University of Szeged Department of Surgery. Patients and method. During a retrospective cohort study including 174 adrenalectomies (28 RP; 146 TP) performed between 1998 and 2021, the following parameters were evaluated: rate of previous abdominal surgeries, conversion rate, operative time, intraoperative blood loss, tumor size, histology, hospital stay, early and late complications. Results. With significantly higher rate of previous abdominal surgeries [TP vs RP: 68 (46.57%) vs 4 (14%) P = 0.0021], there was no markable difference in conversion rate [TP vs RP: 7 (4.79%) vs 5 (18%), P = 0.312]. Significantly larger tumours were removed with TP (TP vs RP: 58.05 vs 34.8 mm, P = 0.016), with no markable difference in intraoperative blood loss (TP vs RP: 67.85 vs 50.2 ml, P = 0.157). Operative time was significantly shorter in TP (TP vs RP: 86.3 vs 134.5 min; P = 0.024). The most frequent histology was adenoma (TP vs RP: n = 95; 65.06% vs 64.3%). Pheochromocytoma occurred in 11 (7.53%) and 5 (17.8%) cases in TP and RP, respectively. We found no significant difference in hospital stay (TP vs RP: 5.125 vs 4.61 day; P = 0.413). Five- and 2 cases of early complications were seen in TP (splenic injury, postoperative fever, severe intraoperative bleeding, severe hypokalemia, surgical site infection) and RP (2 severe intraoperative bleeding), respectively. One lethal case of ventricular fibrillation and one delayed complication (postoperative abdominal wall hernia) were observed in TP. Conclusions. Both TP and RP are safe and simply reproducible minimally invasive techniques. According to our observation, RP adrenalectomy seems to be reserved for smaller lesions, while TP proves to be successful in removing enlarged and also malignant lesions with significantly shorter operative time.</p>","PeriodicalId":74097,"journal":{"name":"Magyar sebeszet","volume":"75 2","pages":"194-199"},"PeriodicalIF":0.0,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10380338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quo vadis chirurgia hepatobiliaria? A máj- és epeúti sebészet 100 éve és napjainkban a Debreceni Sebészeti Klinikán.","authors":"Balázs Nemes, Zsolt Szentkereszty, Dezső Tóth","doi":"10.1556/1046.2021.10010","DOIUrl":"https://doi.org/10.1556/1046.2021.10010","url":null,"abstract":"","PeriodicalId":74097,"journal":{"name":"Magyar sebeszet","volume":" ","pages":"50-57"},"PeriodicalIF":0.0,"publicationDate":"2022-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40327819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nagy Attila Professzor Úr 75 éves.","authors":"Zsolt Szentkeresztesy","doi":"10.1556/1046.2022.10015","DOIUrl":"https://doi.org/10.1556/1046.2022.10015","url":null,"abstract":"","PeriodicalId":74097,"journal":{"name":"Magyar sebeszet","volume":" ","pages":"75"},"PeriodicalIF":0.0,"publicationDate":"2022-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40327823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zsigmond Tóth Csaba, Krisztina Litauszky, Zsolt Susán, Máté Farkas, Péter Nagy, Dániel Mátyási, Balázs Gergely, Dezső Tóth
{"title":"Az érsebészet története a Debreceni Egyetemen.","authors":"Zsigmond Tóth Csaba, Krisztina Litauszky, Zsolt Susán, Máté Farkas, Péter Nagy, Dániel Mátyási, Balázs Gergely, Dezső Tóth","doi":"10.1556/1046.2021.10013","DOIUrl":"https://doi.org/10.1556/1046.2021.10013","url":null,"abstract":"","PeriodicalId":74097,"journal":{"name":"Magyar sebeszet","volume":" ","pages":"65-66"},"PeriodicalIF":0.0,"publicationDate":"2022-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40327821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}