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COVID-19 Impacts on Cancer Treatment—Nosocomial Infection, Therapy Disruption, and Research Application COVID-19对癌症治疗的影响——医院感染、治疗中断及研究应用
Pub Date : 2020-06-01 DOI: 10.18061/ojph.v3i1.9025
P. Connell
No abstract available.
没有可用的摘要。
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引用次数: 0
Web Application to Investigate Butler County Overdose Death Data 调查巴特勒县过量死亡数据的Web应用程序
Pub Date : 2020-06-01 DOI: 10.18061/ojph.v3i1.9019
Alison C. Tuiyott, Bri Clements, A. Bailer, L. Mannix, Jennifer Bailer
Background: Drug overdose deaths, specifically opioid-related deaths, are a public health crisis in the United States with high incidence observed in many Midwestern states, including Ohio. Butler County, Ohio, has the third highest opioid-related death rate in the state. Information on overdose deaths, collected by the county coroner, can serve as a data source for analysis of this public health concern. Given this access, stakeholders can investigate trends in their community for their idiosyncratic interest.Methods: A web application was developed, using the R Shiny package, to visualize and explore the characteris-tics of all overdose deaths in Butler County between 2013 and 2018. Demographics of the decedents, drugs found in the decedents’ postmortem toxicology analyses, annual trends in overdose deaths, and the location of these cases can be examined.Results: The web application provides a graphical user interface that allows a user to request specific analyses and summaries. “Who is dying from opioid overdoses?,” “What drugs, including opioids, are found in people dying from drug overdoses?,” and “Has the number of opioid involved deaths increased in a specific community over time?” are examples of questions that can be explored using this application.Conclusion: This application empowers both the public and local policymakers to investigate the impact of overdose deaths on their communities. Understanding characteristics of the epidemic is an important first step to addressing this problem. The expansion of this application to include other counties in Ohio could be truly beneficial to communities that need it.
背景:药物过量死亡,特别是阿片类药物相关死亡,是美国的一项公共卫生危机,在包括俄亥俄州在内的许多中西部州都观察到高发病率。俄亥俄州巴特勒县是该州阿片类药物相关死亡率第三高的县。县验尸官收集的有关过量死亡的信息可作为分析这一公共卫生问题的数据来源。有了这种访问权限,利益相关者可以调查他们社区的趋势,以满足他们的特殊兴趣。方法:使用R Shiny软件包开发web应用程序,对2013年至2018年巴特勒县所有药物过量死亡的特征进行可视化和探索。可以检查死者的人口统计数据、死者死后毒理学分析中发现的药物、过量死亡的年度趋势以及这些病例的地点。结果:web应用程序提供了一个图形用户界面,允许用户请求特定的分析和摘要。“谁在死于阿片类药物过量?”,“包括阿片类药物在内的哪些药物会在因药物过量而死亡的人身上发现?”以及“随着时间的推移,某个特定社区与阿片类药物相关的死亡人数是否有所增加?”是可以使用此应用程序探索的问题示例。结论:该应用程序使公众和当地政策制定者能够调查过量死亡对其社区的影响。了解这一流行病的特点是解决这一问题的重要第一步。将该应用程序扩展到俄亥俄州的其他县,可能会真正使需要它的社区受益。
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引用次数: 0
Ohio Journal of Public Health Vol. 4, Issue 1 (June 2021): Full Issue 《俄亥俄州公共卫生杂志》第4卷第1期(2021年6月):完整版
Pub Date : 2020-06-01 DOI: 10.18061/ojph.v4i1.8413
Ohio Public Health Association Opha
No abstract available.
没有摘要。
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引用次数: 0
Evaluating the e-Cigarette Epidemic in US Emergency Departments 美国急诊部门电子烟流行情况评估
Pub Date : 2020-06-01 DOI: 10.18061/ojph.v3i1.9018
N. Vallabh, Andrew F. Zheng, Hersh Varma, Ryan Reber, W. Motley
Background: Electronic cigarettes (e-cigarettes) are often thought to be a healthier option to cigarette smoking. e-Cigarettes have been found to overheat and explode. e-Cigarette explosions have caused severe trauma and rendered patients in critical conditions. Inadvertent exposures to liquid nicotine products have caused systemic poisoning injuries. We sought to characterize e-cigarette injuries presenting to emergency departments (ED) in 2018.Methods: We analyzed one year of data from the US Consumer Product Safety Commission’s National Electronic Injury Surveillance System (NEISS). Patients presenting with injuries associated with e-cigarette products were manually identified for inclusion. We performed descriptive analyses on demographic factors, affected bodily regions, dispositions, locations of occurrence, and mechanisms of injury. By applying sample weights, nationally representative estimates were calculated.Results: A total of 361 667 injury cases were reported in NEISS (2018). We identified 50 e-cigarette injury cases, generating a national estimate of 1739 (95% CI [1333-2148]) patients presenting to US EDs with e-cigarette injuries in 2018. Approximately 1000 pediatric patients (age ≤17 years) and 700 adult patients (age ≥18 years) were included. The median age when presenting to the ED was 4 years (interquartile range [IQR], 1-25). Over 85% of injuries occurred at home. Ingestion (55.0%) was the most common mechanism of injury, followed by explosion (35.8%).Conclusion: Children and adults are susceptible to injury from e-cigarette products. Changes in manufacturing standards may prevent injuries from these products.
背景:电子烟通常被认为是比吸烟更健康的选择。电子烟被发现会过热并爆炸。电子烟爆炸造成严重创伤,使患者处于危急状态。无意中接触液体尼古丁产品已造成全身中毒伤害。我们试图描述2018年向急诊科(ED)报告的电子烟伤害情况。方法:我们分析了美国消费品安全委员会国家电子伤害监测系统(NEISS)一年的数据。对出现与电子烟产品相关损伤的患者进行人工识别以纳入研究。我们对人口统计学因素、受影响的身体区域、性格、发生地点和损伤机制进行了描述性分析。通过应用样本权重,计算出了具有全国代表性的估计数。结果:NEISS(2018)共报告361667例损伤病例。我们确定了50例电子烟损伤病例,在2018年,全国估计有1739名(95%置信区间[133-2148])向美国急诊科就诊的电子烟损伤患者。约有1000名儿童患者(年龄≤17岁)和700名成人患者(年龄≥18岁)被纳入。ED的中位年龄为4岁(四分位间距[IQR],1-25)。85%以上的受伤发生在家中。摄入(55.0%)是最常见的伤害机制,其次是爆炸(35.8%)。结论:儿童和成人容易受到电子烟产品的伤害。制造标准的改变可以防止这些产品造成伤害。
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引用次数: 0
An Opportunity for Future Public Health Professionals to Learn from Open Access COVID-19 Data 未来公共卫生专业人员有机会从开放获取的COVID-19数据中学习
Pub Date : 2020-06-01 DOI: 10.18061/ojph.v3i1.9024
Robert C. Orellana, Angie Hetrick, S. Chettri, Zachary A Weber, Sara Conroy
No abstract available.
没有摘要。
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引用次数: 0
Association of Perfluoroalkyl Substance with Lung Function in the US Population 全氟烷基物质与美国人群肺功能的相关性
Pub Date : 2019-12-01 DOI: 10.18061/ojph.v2i2.9032
Brenna C. Heinle, T. Crawford, Sara J. Paton, N. Khalil
Background/Aim: Perfluoroalkyl substances (PFASs) are chemical compounds used in consumer products and are linked with increases in cholesterol, thyroid disease, and pregnancy-induced hypertension. However, their association with lung function is not completely understood.Methods: Cross-sectional 2011-2012 US population data from the National Health and Nutrition Examination Survey (NHANES) were analyzed (n = 1450, aged 12 to 79 years, 50.5% females). Serum concentrations of 4 PFASs, perfluoronon-anoic acid (PFNA), perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorohexane sulfonic acid (PFHxS), were assessed using mass spectrometry and categorized into quartiles. Lung function was measured by spirome-try as forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and the ratio of FEV1/FVC (%). Survey weighted sex stratified adjusted linear regression analysis was used to predict lung function with PFASs quartiles.Results: In males, compared to females, all 4 PFASs serum concentrations and lung function indices were higher, except FEV1/FVC (%) which was lower than females. No association of any PFAS with decrease in lung function was seen in multivariable-adjusted models in both males and females.Conclusion: In this exploratory analysis, PFAS exposure was not associated with lung function. PFAS contamina-tion has been ongoing for many years across the US and Ohio, and cleanup efforts are now underway. The association between PFAS exposure and lung function needs further exploration in longitudinal studies.
背景/目的:全氟烷基物质(PFASs)是用于消费品的化合物,与胆固醇、甲状腺疾病和妊娠高血压的增加有关。然而,它们与肺功能的关系尚不完全清楚。方法:对2011-2012年美国国家健康与营养调查(NHANES)的人口数据进行横断面分析(n = 1450,年龄12 - 79岁,50.5%为女性)。使用质谱法评估4种全氟磺酸、全氟壬酸(PFNA)、全氟辛酸(PFOA)、全氟辛烷磺酸(PFOS)和全氟己烷磺酸(PFHxS)的血清浓度,并将其分为四分位数。肺活量法测定肺功能为用力肺活量(FVC)、1秒用力呼气量(FEV1)、FEV1/FVC比值(%)。采用调查加权性别分层调整线性回归分析预测PFASs四分位数的肺功能。结果:男性4种PFASs血清浓度和肺功能指标均高于女性,但FEV1/FVC(%)低于女性。在男性和女性的多变量调整模型中,没有发现任何PFAS与肺功能下降的关联。结论:在这项探索性分析中,PFAS暴露与肺功能无关。PFAS污染在美国和俄亥俄州已经持续了多年,目前正在进行清理工作。PFAS暴露与肺功能的关系有待于进一步的纵向研究。
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引用次数: 0
Routine Screening of Adolescents for Trichomonas vaginalis in a Juvenile Detention Center 青少年拘留所青少年阴道毛滴虫常规筛查
Pub Date : 2019-12-01 DOI: 10.18061/ojph.v2i2.9028
Shaketha A. Gray, A. Bonny, S. Matson, C. Holland-Hall
Background: Detained and incarcerated adolescents are at increased risk of sexually transmitted infections (STI), but limited information is currently available regarding the prevalence of Trichomonas vaginalis (TV) in detained youth.Methods: A total of 144 detainees (75 males and 69 females) in the Franklin County Juvenile Detention Facility (FCJDF) in Columbus, Ohio, consented to STI screening between May 2016 and June 2017. Participants were screened for TV in addition to Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) using urine nucleic acid amplification tests (NAAT).Results: Among detained youth who consented to testing, TV was identified in 7 of 69 (10.1%) females and 0 of 75 (0%) males (P <0.01). Neisseria gonorrhoeae was identified in 12 of 69 (17.4%) females and 3 of 75 (4.0%) males (P = 0.01), and CT was identified in 16 of 69 (23.2%) female and 7 of 75 (9.3%) male detainees (P = 0.04). Among females, positive TV screen was associated with prior history of STI.Conclusion: Our data support routine screening of female detainees at FCJDF, based on our finding of 10% posi-tivity among females who underwent testing.
背景:被拘留和监禁的青少年性传播感染(STI)的风险增加,但目前关于被拘留青少年阴道毛滴虫(TV)流行率的信息有限。方法:2016年5月至2017年6月,俄亥俄州哥伦布市富兰克林县青少年拘留所共有144名被拘留者(75名男性和69名女性)同意接受STI筛查。除淋病奈瑟菌(NG)和沙眼衣原体(CT)外,还使用尿液核酸扩增试验(NAAT)对参与者进行了TV筛查,69名女性中有16人(23.2%)和75名男性被拘留者中有7人(9.3%)发现了CT(P=0.04)。在女性中,电视筛查阳性与STI病史有关。结论:我们的数据支持FCJDF对女性被拘留者的常规筛查,因为我们发现接受检测的女性中有10%的阳性率。
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引用次数: 0
An Examination of Dental Health Among Metropolitan and Appalachian Adolescents in Ohio. 俄亥俄州大都市和阿巴拉契亚地区青少年牙齿健康状况的调查。
Pub Date : 2019-12-01
Kyle Bader, Megan E Roberts, Brittney Keller-Hamilton

Background: Poor dental health is a common chronic condition among youth. Appalachian versus metropolitan residence, socioeconomic status, and health behaviors contribute to poor dental health. Limited research has directly compared dental health and risk factors for poor dental health among Appalachian and metropolitan youth. We examined the association between dental health and residence among adolescent boys and explored socioeconomic and behavioral factors that may contribute to differences in dental health.

Methods: Adolescent males from metropolitan and rural Appalachian Ohio (n = 1220, age 11-16 years) reported their diet and tobacco use. Parents or guardians reported when boys had last visited the dentist and rated their dental health (excellent/very good/good versus fair/poor). Unadjusted logistic regression modeled the association between fair/poor dental health and residence (metropolitan versus Appalachian). Adjusted analyses controlled for race, household income, dental visits, diet, and tobacco use.

Results: Appalachian (versus metropolitan) boys were more likely to have used tobacco in the past 30 days and consumed fewer fruit and vegetables, more added sugar, and more sugary beverages. The relation between dental health and Appalachian versus metropolitan residence did not reach statistical significance, and adjusting for behavioral factors did little to change the observed association.

Conclusion: Our findings suggest that some of the urban/rural disparities in dental health observed in other studies may be related to behavioral factors like tobacco use and diet, but much remains unexplained. We provide support for behavioral interventions to address these issues in the Appalachian community.

背景:牙齿健康状况不佳是青少年中一种常见的慢性疾病。阿巴拉契亚与大都市居住、社会经济地位和健康行为导致牙齿健康状况不佳。有限的研究直接比较了阿巴拉契亚和大都市青年的牙齿健康和牙齿健康不良的危险因素。我们研究了青春期男孩牙齿健康与居住地之间的关系,并探讨了可能导致牙齿健康差异的社会经济和行为因素。方法:来自俄亥俄州阿巴拉契亚市区和农村的青少年男性(n = 1220,年龄11-16岁)报告了他们的饮食和烟草使用情况。父母或监护人报告了男孩最后一次看牙医的时间,并对他们的牙齿健康状况进行了评分(极好/非常好/好与一般/差)。未调整的逻辑回归模拟了良好/不良牙齿健康与居住地之间的关联(大都市与阿巴拉契亚地区)。调整后的分析控制了种族、家庭收入、牙科就诊、饮食和烟草使用等因素。结果:阿巴拉契亚地区(与大都市相比)的男孩在过去30天内更有可能使用烟草,摄入的水果和蔬菜更少,添加糖更多,含糖饮料更多。牙齿健康与阿巴拉契亚和大都市居住之间的关系没有达到统计学意义,并且调整行为因素对观察到的关联几乎没有改变。结论:我们的研究结果表明,在其他研究中观察到的一些城市/农村牙齿健康差异可能与吸烟和饮食等行为因素有关,但仍有许多原因无法解释。我们为行为干预提供支持,以解决阿巴拉契亚社区的这些问题。
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引用次数: 0
HPV Vaccine Coverage among Adolescent Males in Ohio: Results of a Longitudinal Study. 俄亥俄州青少年男性HPV疫苗覆盖率:一项纵向研究的结果
Pub Date : 2019-12-01 DOI: 10.18061/ojph.v2i2.9030
Andreas A Teferra, Brittney Keller-Hamilton, Megan E Roberts, Paul L Reiter

Background: Human papillomavirus (HPV) vaccine has been recommended for males in the United States since 2011, yet little is known about vaccine coverage among adolescent males in Ohio. Our longitudinal study examined HPV vaccine coverage among adolescent males in Ohio and identified predictors of vaccination.

Methods: The Buckeye Teen Health Study recruited adolescent males ages 11-16 and their parents from one urban county and nine rural counties in Ohio. We report longitudinal vaccination data on 1126 adolescent males, with baseline data from 2015-2016 and follow-up data from 2017-2018. We used multivariable Poisson regression to identify predictors of HPV vaccine initiation that occurred between baseline and follow-up.

Results: At baseline, 42.4% of parents reported their sons had initiated the HPV vaccine series. Among parents whose sons were unvaccinated at baseline, 36.3% indicated initiation at follow-up. Initiation at follow-up was more common among sons who had received influenza vaccine (RR = 1.54, 95% CI = 1.08-2.18) or whose parents indicated lack of a recent visit to a doctor as the main reason for not yet vaccinating at baseline (RR = 1.41, 95% CI = 1.02-1.95). Initiation was less common among sons whose parents had an associate's degree or some college education (RR = 0.28, 95% CI = 0.46-0.99). Main reasons for not vaccinating changed from baseline to follow-up among parents of unvaccinated sons.

Conclusions: Although HPV vaccine initiation increased over time, many adolescent males in Ohio remain unvaccinated. Findings can help guide future strategies for increasing HPV vaccine coverage among this population.

背景:自2011年以来,美国已推荐男性接种人乳头瘤病毒(HPV)疫苗,但对俄亥俄州青少年男性的疫苗覆盖率知之甚少。我们的纵向研究检查了俄亥俄州青少年男性的HPV疫苗覆盖率,并确定了疫苗接种的预测因素。方法:七叶树青少年健康研究招募了来自俄亥俄州一个城市县和九个农村县的11-16岁青少年男性及其父母。我们报告了1126名青少年男性的纵向疫苗接种数据,包括2015-2016年的基线数据和2017-2018年的随访数据。我们使用多变量泊松回归来确定基线和随访期间HPV疫苗启动的预测因素。结果:在基线时,42.4%的父母报告他们的儿子已经开始接种HPV疫苗系列。在基线时儿子未接种疫苗的父母中,36.3%的人表示在随访时开始接种疫苗。在接受过流感疫苗的儿子(RR = 1.54, 95% CI = 1.08-2.18)或其父母表示最近没有去看医生是未在基线时接种疫苗的主要原因(RR = 1.41, 95% CI = 1.02-1.95)中,在随访时开始接种更为常见。父母有大专或大专学历的儿子入会较少(RR = 0.28, 95% CI = 0.46-0.99)。未接种疫苗的儿子的父母未接种疫苗的主要原因从基线到随访发生变化。结论:尽管HPV疫苗接种率随着时间的推移而增加,但俄亥俄州的许多青少年男性仍未接种疫苗。研究结果可以帮助指导未来在这一人群中提高HPV疫苗覆盖率的策略。
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引用次数: 0
Impact of Emotional Distress on Prescription Opioid Abuse in a Rural Juvenile Drug Court Sample 情绪困扰对农村青少年毒品法庭处方阿片类药物滥用的影响
Pub Date : 2019-12-01 DOI: 10.18061/ojph.v2i2.9033
Ross M. Kauffman, K. Durkin
Background: Ohio is at the epicenter of the opioid epidemic, and the current crisis disproportionately burdens rural areas. The Self-Medication Hypothesis and work examining adverse childhood experiences posit that drug use may be understood as a coping strategy to address emotional distress.Methods: Juvenile drug court participants in a Northwest Ohio county were administered a standardized biopsychosocial assessment. Intake interviews from January 2010 and November 2018 were used to evaluate the relationship between emotional distress reported using the Emotional Problem Scale (EPS) and lifetime nonmedical use of prescription opioids. Linear regression was used to examine temporal trends in EPS scores. Logistic regression was used to examine the relationship between EPS scores and prescription opioid misuse, controlling for temporal trends.Results: Linear regression showed a significant increase in emotional distress over the study period for both pre-scription opioid users and nonusers. Average scores increased 29.5 points (on a 100 point scale) over the duration of the study (P <0.0001). A 10-point increase in EPS score was associated with a nearly 50% increase in the lifetime odds of pre-scription opioid misuse (OR = 1.46, 95% CI: 1.19-1.82, P = 0.0004). The odds of prescription opioid misuse declined each year (OR = 0.63, 95% CI: 0.48-0.81, P = 0.0006).Conclusion: Rates of prescription opioid misuse have decreased over time despite a significant association be-tween emotional distress and opioid misuse and trend toward increasing EPS scores. While efforts to reduce prescription opioid misuse appear to have been effective in this population, significant work is needed to reduce underlying risk fac-tors.
背景:俄亥俄州是阿片类药物流行的中心,当前的危机给农村地区带来了不成比例的负担。自我用药假说和对儿童不良经历的研究表明,药物使用可以被理解为解决情绪困扰的一种应对策略。方法:对俄亥俄州西北部一个县的青少年毒品法庭参与者进行标准化的生物心理社会评估。2010年1月至2018年11月的入院访谈用于评估使用情绪问题量表(EPS)报告的情绪困扰与终生非药物使用处方阿片类药物之间的关系。线性回归用于检验EPS评分的时间趋势。Logistic回归用于检验EPS评分与处方阿片类药物滥用之间的关系,控制时间趋势。结果:线性回归显示,在研究期间,处方阿片类药物使用者和非使用者的情绪困扰都显著增加。在研究期间,平均得分增加了29.5分(100分制)(P<0.0001)。EPS得分增加10分与描述前阿片类药物滥用的终生几率增加近50%有关(OR=1.46,95%CI:1.19-1.82,P=0.0004)。处方阿片类药滥用的几率每年都在下降(OR=0.63,95%CI:0.48-0.81,P=0.0006)处方阿片类药物滥用随着时间的推移而减少,尽管情绪困扰和阿片类物质滥用之间存在显著关联,并且EPS评分呈上升趋势。虽然减少处方阿片类药物滥用的努力在这一人群中似乎是有效的,但还需要大量工作来减少潜在的风险因素。
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引用次数: 2
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Ohio journal of public health
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