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Association of co-morbid insomnia and sleep apnoea symptoms with all-cause mortality: Analysis of the NHANES 2005-2008 data. 合并症失眠和睡眠呼吸暂停症状与全因死亡率的关系:NHANES 2005-2008数据分析
Pub Date : 2022-12-01 DOI: 10.1016/j.sleepe.2022.100043
Alexander Sweetman , Bastien Lechat , Sarah Appleton , Amy Reynolds , Robert Adams , Yohannes Adama Melaku

Background

Co-morbid insomnia and sleep apnoea (COMISA) is a highly prevalent condition associated with negative health outcomes. This population-based study aimed to investigate the association between COMISA and all-cause mortality.

Methods

Sleep data in 6,877 participants (Age median [IQR]=45 [33,57], 50.1% male) were drawn from the National Health and Nutrition Examination Survey (2005-2008). Insomnia was defined as difficulties initiating sleep, long awakenings, and/or early morning awakenings on ≥16 nights/month, with daytime impairment. The STOP-Bang questionnaire was used to identify participants at high risk of obstructive sleep apnoea (OSA). COMISA was defined if participants met criteria for insomnia and high risk OSA. The median (IQR) follow-up for mortality was 8.6 (7.8, 9.8) years. Cox regression models were used to determine the association between COMISA and all-cause mortality, controlling for socio-demographic characteristics, behavioural factors and chronic conditions.

Results

The prevalence of no insomnia/OSA, insomnia-alone, OSA-alone, and COMISA were 73.5, 3.0, 20.1, and 3.3%, respectively, and 6.7% of participants died by 11-year follow-up. Compared to participants with no insomnia/OSA, higher mortality risk was observed in participants with COMISA (HR=1.9; 95%CI=1.3-2.8) and insomnia alone (HR=1.5; 95%CI=1.0-2.3) after adjusting for socio-demographic characteristics, and behavioural factors. The relationship between COMISA and mortality persisted after additionally controlling for chronic conditions, sleep duration and sleeping pill use (HR=1.6; 95%CI=1.1-2.3), but the relationship between insomnia-alone and mortality did not (HR=1.4; 95%CI=0.9-2.3).

Conclusion

Co-morbid insomnia and high-risk OSA is associated with increased risk of all-cause mortality. More research is needed to identify effective treatments for COMISA.

背景:合并症失眠和睡眠呼吸暂停(COMISA)是一种非常普遍的与负面健康结果相关的疾病。这项基于人群的研究旨在调查COMISA与全因死亡率之间的关系。方法选取2005-2008年全国健康与营养检查调查6877名参与者(年龄中位数[IQR]=45[33,57],男性50.1%)的睡眠资料。失眠定义为入睡困难、长时间醒来和/或清晨醒来≥16晚/月,伴有白天障碍。STOP-Bang问卷用于识别阻塞性睡眠呼吸暂停(OSA)高风险的参与者。如果参与者符合失眠和高风险OSA的标准,则定义COMISA。死亡率的中位随访(IQR)为8.6(7.8,9.8)年。使用Cox回归模型确定COMISA与全因死亡率之间的关系,控制社会人口统计学特征、行为因素和慢性病。结果无失眠/OSA、单纯性失眠、单纯性OSA和COMISA患病率分别为73.5%、3.0、20.1%和3.3%,随访11年死亡的比例为6.7%。与没有失眠/OSA的参与者相比,COMISA参与者的死亡风险更高(HR=1.9;95%CI=1.3-2.8)和单纯失眠(HR=1.5;95%CI=1.0-2.3),校正了社会人口统计学特征和行为因素。在另外控制慢性病、睡眠时间和安眠药使用后,COMISA与死亡率的关系仍然存在(HR=1.6;95%CI=1.1-2.3),但单独失眠与死亡率之间没有关系(HR=1.4;95% ci = 0.9 - -2.3)。结论合并症失眠和高危OSA与全因死亡风险增加相关。需要更多的研究来确定COMISA的有效治疗方法。
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引用次数: 9
Parental socioeconomic status and childhood sleep: A systematic review and meta-analysis 父母社会经济地位与儿童睡眠:系统回顾和荟萃分析
Pub Date : 2022-12-01 DOI: 10.1016/j.sleepe.2022.100047
Emily E. Cameron , Dana Watts , Katherine Silang , Ashley Dhillon , Pooja R. Sohal , Anna L. MacKinnon , Leslie E. Roos , Lianne M. Tomfohr-Madsen

Context

Parental socioeconomic status (SES) is increasingly understood to be a key contributor to sleep health, but the research in childhood has not been synthesized.

Objective

To examine the associations between indicators of child SES and child sleep (≤18 years old), we conducted a systematic review and meta-analyses.

Data sources

CINAHL with Full Text, PsycINFO, MEDLINE/PubMed, and Embase were searched using terms to define SES and childhood to ascertain all relevant, peer-reviewed articles from database inception to 27 December 2019.

Study selection

Studies were included if an association between an indicator of parental SES and a measure of child sleep (duration, quality, and problems) was reported.

Data extraction

Data was extracted from 46 studies (N = 72,915). Across these studies, total sample size across participants included in the meta-estimate was N = 69,373.

Results

Data was extracted from 46 studies (N = 72,915). Across these studies, total sample size across participants included in the meta-estimate was N = 69,373. Higher parental education was associated with longer childhood sleep duration (stronger in samples with a higher proportion of White children) (OR = 1.302, 95% CI [1.111, 1.526], p = .001) and better sleep quality (OR = 1.332, 95% CI [1.014, 1.751], p = .040). Parental education was not directly associated with child sleep problems (OR = 1.191, 95% CI [0.733, 1.935], p = .479); moderation occurred by continent and the relationship was more pronounced in the Asian meta-estimate. Higher household income was not directly associated with longer childhood sleep duration (OR = 0.570, 95% CI [0.167, 1.943], p = 0.369), but moderation occurred by higher quality studies and the proportion of White children in the sample. Higher household income was associated with fewer sleep problems (moderated by continent) (OR = 0.764 (95% CI [0.689, 0.848], p < .001) and higher sleep quality (OR = 1.558, 95% CI [1.036, 2.342], p = .033).

Limitations

This review was limited by the number and methods of available published studies meeting inclusion criteria.

Conclusions

Preventative programs that emphasize improvements in sleep of children and adolescents growing up in lower SES families are needed.

父母的社会经济地位(SES)越来越被认为是睡眠健康的一个关键因素,但对儿童的研究尚未得到综合。目的探讨儿童SES指标与儿童睡眠(≤18岁)之间的关系,进行系统回顾和meta分析。使用定义SES和childhood的术语搜索cinahl全文、PsycINFO、MEDLINE/PubMed和Embase,以确定从数据库建立到2019年12月27日所有相关的同行评审文章。研究选择如果父母的社会经济地位指标与儿童睡眠(持续时间、质量和问题)测量之间存在关联,则纳入研究。数据提取数据提取自46项研究(N = 72,915)。在这些研究中,纳入meta估计的参与者的总样本量为N = 69,373。结果数据来自46项研究(N = 72,915)。在这些研究中,纳入meta估计的参与者的总样本量为N = 69,373。父母教育程度越高,儿童睡眠时间越长(白人儿童比例越高)(OR = 1.302, 95% CI [1.111, 1.526], p = .001),睡眠质量越好(OR = 1.332, 95% CI [1.014, 1.751], p = .040)。父母教育与儿童睡眠问题无直接关系(OR = 1.191, 95% CI [0.733, 1.935], p = .479);调节发生在各大洲,在亚洲元估计中关系更为明显。较高的家庭收入与较长的儿童睡眠时间没有直接关系(OR = 0.570, 95% CI [0.167, 1.943], p = 0.369),但高质量的研究和样本中白人儿童的比例出现了调节。较高的家庭收入与较少的睡眠问题相关(受大洲影响)(OR = 0.764 (95% CI [0.689, 0.848], p <.001)和更高的睡眠质量(OR = 1.558, 95% CI [1.036, 2.342], p = 0.033)。本综述受到符合纳入标准的已发表研究的数量和方法的限制。结论强调改善社会经济地位较低家庭的儿童和青少年睡眠的预防项目是必要的。
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引用次数: 0
Unprecedented times and uncertain connections: A systematic review examining sleep problems and screentime during the COVID-19 pandemic 前所未有的时代和不确定的联系:一项关于COVID-19大流行期间睡眠问题和屏幕时间的系统综述
Pub Date : 2022-12-01 DOI: 10.1016/j.sleepe.2022.100029
Kathryn Drumheller, Chia-Wei Fan

Objective

Sleep has been impacted by the COVID-19 pandemic around the world. Furthermore, screen time has been reported to influence sleep and has increased during pandemic quarantines. This systematic review searched databases to determine if screen time affected sleep during the COVID-19 pandemic.

Methods

PubMed, Nursing and Allied Health Proquest, and Science Direct Health and Lifescience college edition were searched for articles that fit the inclusion criteria. There were 2750 articles initially screened. Then, 119 articles were further assessed to determine eligibility, creating a final sample of 18 articles that explored whether screen time affected sleep.

Results

After reviewing the included articles (n = 18), the main theme revealed that screen time negatively affected sleep during the COVID-19 pandemic, specifically aspects such as sleep duration, sleep quality, sleep onset latency, and wake time. However, several articles countered this implication. Therefore, it is important to consider other factors that may influence the relationship between screen time and sleep.

Conclusions

Although the number of articles included is limited, the overall synthesis suggests that COVID-19-related lifestyle changes, such as increased screen time, may negatively affect sleep health. However, other unidentified factors may have contributed to these findings and warrant further research. Nonetheless, community leaders must consider the long-term consequences of the pandemic and implement initiatives to address sleep challenges due to the intricate connection between sleep and well-being.

目的2019冠状病毒病(COVID-19)全球大流行对睡眠造成了影响。此外,据报道,屏幕时间会影响睡眠,并且在大流行隔离期间会增加。本系统综述检索了数据库,以确定在COVID-19大流行期间,屏幕时间是否会影响睡眠。方法检索spubmed、Nursing and Allied Health Proquest、Science Direct Health and Lifescience college edition等符合纳入标准的文章。最初筛选了2750篇文章。然后,对119篇文章进行进一步评估,以确定是否符合资格,最终得出18篇文章的样本,这些文章探讨了屏幕时间是否会影响睡眠。在回顾纳入的文章(n = 18)后,主题揭示了在COVID-19大流行期间,屏幕时间对睡眠产生负面影响,特别是在睡眠持续时间、睡眠质量、睡眠发作潜伏期和醒来时间等方面。然而,有几篇文章反驳了这种说法。因此,考虑其他可能影响屏幕时间和睡眠之间关系的因素是很重要的。尽管纳入的文章数量有限,但总体综合表明,与covid -19相关的生活方式改变,如屏幕时间增加,可能会对睡眠健康产生负面影响。然而,其他未确定的因素可能导致了这些发现,值得进一步研究。尽管如此,社区领导人必须考虑到疫情的长期后果,并采取措施应对睡眠挑战,因为睡眠与健康之间存在复杂的联系。
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引用次数: 6
Sleep quality of adult tobacco users: A systematic review of literature and meta-analysis 成人烟草者的睡眠质量:文献综述和荟萃分析
Pub Date : 2022-12-01 DOI: 10.1016/j.sleepe.2022.100028
Wennyo Camilo da Silva e Silva , Nathália Lima Costa , Douglas da Silva Rodrigues , Marianne Lucena da Silva , Katiane da Costa Cunha

Human sleep is fundamental for organic functions to occur properly. Therefore, lack of adequate sleep can impair cognitive function, which in turn causes emotional problems, memory changes and the onset of diseases. However, it is worth noting that sleep is influenced by external factors, such as tobacco usage. In this sense, our goal is to analyze studies that have the influence of tobacco consumption on the sleep quality of adults as the object of their research. A high-sensibility search was performed in databases (Virtual Health Library [Biblioteca Virtual em Saúde – BVS], Scielo, Medline via Pubmed, Cochrane, Embase, Web of Science, Scopus, PsycoInfo, Cinahl) using descriptors linked to tobacco consumption and sleep habits. 19 studies originating from 10 countries were included, with a total sample of 15245 participants; 10 studies were selected for the meta-analysis. It was identified that smoking tobacco affects sleep characteristics — such as quality, maintenance, and duration — with females and those who use tobacco more heavily having greater alterations.

人类的睡眠是身体机能正常运转的基础。因此,缺乏充足的睡眠会损害认知功能,进而导致情绪问题、记忆变化和疾病的发作。然而,值得注意的是,睡眠受到外部因素的影响,比如吸烟。从这个意义上说,我们的目标是分析以吸烟对成年人睡眠质量影响为研究对象的研究。使用与烟草消费和睡眠习惯相关的描述词在数据库(虚拟健康图书馆[Biblioteca Virtual em Saúde - BVS]、Scielo、Medline via Pubmed、Cochrane、Embase、Web of Science、Scopus、PsycoInfo、Cinahl)中进行高灵敏度搜索。纳入了来自10个国家的19项研究,共15245名参与者;选取10项研究进行meta分析。研究发现,吸烟会影响睡眠特征,如质量、维持和持续时间,其中女性和吸烟更严重的人受到的影响更大。
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引用次数: 3
Racial/ethnic minorities have greater declines in sleep duration with higher risk of cardiometabolic disease: An analysis of the U.S. National Health Interview Survey 美国国家健康访谈调查的一项分析显示,少数民族的睡眠时间减少幅度更大,患心脏代谢疾病的风险也更高
Pub Date : 2022-12-01 DOI: 10.1016/j.sleepe.2022.100022
Andrew S. Tubbs , Sadia B. Ghani , Dora Valencia , Girardin Jean-Louis , William D.S. Killgore , Fabian-Xosé Fernandez , Michael A. Grandner

Objective

Habitual insufficient sleep may contribute to cardiometabolic disease in the United States, particularly among racial and ethnic minorities. However, there is mixed evidence on secular trends in U.S. sleep duration.

Study design

Cross-sectional data from 413,417 individuals were acquired from the National Health Interview Survey from 2005–2018. Variables included self-reported sleep duration as well as lifetime diagnosis of hypertension, coronary heart disease, diabetes, and pre-diabetes, and obesity. Population-weighted robust Poisson models estimated annual trends in sleep duration and the prevalence risk ratios (PRR) of cardiometabolic disease as a function of sleep duration.

Setting

Population-based survey.

Results

Daily sleep duration decreased -0.62 min ([-0.71, 0.54], p < 0.01) annually from 2005–2018. However, this decline began only after 2010, when sleep duration fell by 1.04 min ([-1.21, -0.86], p < 0.01) each year. This trend varied by race (two-way ANOVA, p = 0.02), such that Mexican Hispanic individuals saw a greater decline (-1.83 [-2.37, -1.30] min per year, p < 0.01) than whites (-0.83 [-1.02, -0.64] min per year, p < 0.01). Additionally, a 1-h loss in daily sleep duration was linked to 4% greater prevalence of hypertension (PRR: 1.04, [1.04, 1.05]), 3% greater prevalence of diabetes (PRR: 1.03 [1.01, 1.05]), and 8% greater prevalence of obesity (PRR: 1.08 [1.07, 1.09]) after adjusting for age, sex, employment, marital status, and survey year.

Conclusions

There is a secular decline in U.S. daily sleep duration that is greater among Mexican Hispanic individuals. Moreover, reduced sleep duration is associated with more prevalent cardiometabolic disease.

目的:在美国,习惯性睡眠不足可能导致心脏代谢疾病,尤其是在少数种族和族裔人群中。然而,关于美国人睡眠时间的长期趋势,有各种各样的证据。研究设计从2005年至2018年的全国健康访谈调查中获得了413,417人的横断面数据。变量包括自我报告的睡眠时间,以及高血压、冠心病、糖尿病、糖尿病前期和肥胖的终生诊断。人口加权稳健泊松模型估计了睡眠持续时间的年度趋势和心脏代谢疾病的患病率风险比(PRR)作为睡眠持续时间的函数。SettingPopulation-based调查。结果每日睡眠时间减少-0.62 min ([-0.71, 0.54], p <从2005年至2018年每年0.01)。然而,这种下降仅在2010年之后才开始,当时睡眠时间减少了1.04分钟([-1.21,-0.86],p <每年0.01)。这一趋势因种族而异(双向方差分析,p = 0.02),例如墨西哥裔西班牙裔个体的下降幅度更大(每年-1.83[-2.37,-1.30]分钟,p <0.01)比白人(-0.83 [-1.02,-0.64]min /年,p <0.01)。此外,在调整年龄、性别、就业、婚姻状况和调查年份后,每天睡眠时间减少1小时与高血压患病率增加4% (PRR: 1.04,[1.04, 1.05])、糖尿病患病率增加3% (PRR: 1.03[1.01, 1.05])和肥胖患病率增加8% (PRR: 1.08[1.07, 1.09])相关。结论:美国人每日睡眠时间的长期下降趋势在墨西哥裔西班牙人中更为明显。此外,睡眠时间缩短与更普遍的心脏代谢疾病有关。
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引用次数: 0
Sex and racial/ethnic disparities in sleep duration and timing on weekdays and weekends across lifespan in the US population 美国人一生中工作日和周末睡眠时间和时间的性别和种族差异
Pub Date : 2022-12-01 DOI: 10.1016/j.sleepe.2022.100026
Chao Cao , Lin Yang

Background

Sleep affects health. Sleep habits differ between population subgroups and may also differ between weekdays and weekends; however, these patterns are rarely described at the population level.

Purpose

To investigate age and racial/ethnic differences in sleep duration and timing between weekdays (workdays) and weekends (non-workdays).

Methods

A cross-sectional analysis of the US nationally representative data from the National Health and Nutrition Examination Survey among adolescents (16-19 years) and adults (≥20 years).

Results

Data on 10069 individuals were analyzed (51% female), including 959 adolescents and 9110 adults. The hours per night of sleep were shorter during weekdays (7.6, 95%CI: 7.6 to 7.7) than on weekends (8.3, 95% CI: 8.3 to 8.2). Females slept shorter hours than males on weekdays (7.7 [95%CI, 7.7 to 7.8] vs. 7.5 [95%CI, 7.4 to 7.5]) and on weekends (8.5, [95%CI, 8.4 to 8.5] vs. 8.2 [95% CI, 8.1 to 8.2]). Non-Hispanic blacks (7.4, 95% CI: 7.4 to 7.5) reported the shortest weekdays sleep. With respect to sleep timing, comparing to weekdays, males reported 30-min delayed weekends bedtime (23:30 [IQR, 22:30-00:30] vs. 23:00 [IQR, 22:00-00:00]), whereas both sexes reported 1.5-hour delayed weekends wake-up time (male: 07:30 [IQR, 06:30-09:00] vs. 06:00 [IQR, 05:30-07:30]; female: 08:00 [IQR, 06:30-09:00] vs. 06:30 [IQR, 05:30-07:30]). The delayed weekend bedtime and wake-up times were observed in all racial/ethnic groups.

Conclusions

In the US population, sleep habits differed between weekdays and weekends. Shorter sleep hours and delayed sleep timing were noted and more apparent among racial/ethnic minorities of both sexes.

睡眠影响健康。不同人群的睡眠习惯不同,工作日和周末的睡眠习惯也可能不同;然而,很少在人口水平上描述这些模式。目的探讨年龄和种族/民族在工作日(工作日)和周末(非工作日)睡眠时间和时间上的差异。方法对美国青少年(16-19岁)和成人(≥20岁)健康与营养调查中具有全国代表性的数据进行横断面分析。结果共收集数据10069例,其中女性占51%,其中青少年959例,成人9110例。工作日每晚睡眠时间(7.6小时,95%CI: 7.6至7.7小时)比周末(8.3小时,95%CI: 8.3至8.2小时)短。女性在工作日的睡眠时间比男性短(7.7 [95%CI, 7.7至7.8]比7.5 [95%CI, 7.4至7.5]),周末的睡眠时间比男性短(8.5,[95%CI, 8.4至8.5]比8.2 [95%CI, 8.1至8.2])。非西班牙裔黑人(7.4,95% CI: 7.4 - 7.5)工作日睡眠时间最短。在睡眠时间方面,与工作日相比,男性报告周末睡觉时间延迟30分钟(23:30 [IQR, 22:30-00:30] vs. 23:00 [IQR, 22:00-00:00]),而两性报告周末起床时间延迟1.5小时(男性:07:30 [IQR, 06:30-09:00] vs. 06:00 [IQR, 05:30-07:30];女:08:00 [IQR, 06:30-09:00] vs. 06:30 [IQR, 05:30-07:30])。在所有种族/民族群体中都观察到周末睡觉和起床时间的延迟。结论:在美国人群中,工作日和周末的睡眠习惯不同。睡眠时间较短和睡眠时间延迟的现象在男女少数族裔中更为明显。
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引用次数: 4
Epidemiological studies on sleep quality can help in improving public mental health initiatives and development of better sleep technologies 关于睡眠质量的流行病学研究可以帮助改善公共精神卫生倡议和开发更好的睡眠技术
Pub Date : 2022-12-01 DOI: 10.1016/j.sleepe.2022.100049
Jitendra Kumar Sinha , Kshitij Vashisth , Shampa Ghosh
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引用次数: 2
Public interest and awareness regarding general health, sleep quality and mental wellbeing during the early COVID-19 pandemic period: An exploration using Google trends 在COVID-19大流行早期,公众对一般健康、睡眠质量和心理健康的兴趣和意识:利用谷歌趋势进行探索
Pub Date : 2022-12-01 DOI: 10.1016/j.sleepe.2021.100017
Patrick Lemoine , David Ebert , Yoshihiko Koga , Claire Bertin

The internet network continues to be a major source of health-related information. Our research provides insights into the online health-seeking behaviors of the general population, and evaluates the potential relationship between the COVID-19 pandemic and public interest and awareness of general sleep health, mental health and wellbeing.

Google Trends’ weekly relative search volumes (RSVs) were examined during 2020 for searches specifically related to COVID-19 symptoms, and for searches related to general health, sleep and wellbeing, in the United Kingdom, the United States of America, France, Italy and Japan. To obtain insight into the association between the initiation of public restrictions and online search trends, we assessed a six-week period; the ‘early pandemic period’ (EPP) (01 March 2020 – 11 April 2020). To provide a meaningful pre-pandemic comparison, a similar period during 2019 (03 March – 13 April 2019) was compared for RSV and median difference analysis.

The EPP was associated with increased online searches related to COVID-19 symptoms, as compared with those related to more general sleep health, mental health and wellbeing. The latter search terms frequently showed a decrease or minimal change in RSV during the EPP compared with the equivalent period in 2019. This finding illustrates the potential link between the COVID-19 pandemic and online search behavior and corroborates existing findings regarding internet searches during this period.

Proactive communication by healthcare professionals during future pandemics and as an ongoing measure could help prevent public neglect of general health and wellbeing symptoms, and encourage reporting and early intervention.

互联网仍然是与健康有关的信息的主要来源。我们的研究提供了对普通人群在线就医行为的见解,并评估了COVID-19大流行与公众对一般睡眠健康,心理健康和福祉的兴趣和意识之间的潜在关系。在英国、美利坚合众国、法国、意大利和日本,研究了2020年期间谷歌趋势的每周相对搜索量(rsv),包括与COVID-19症状具体相关的搜索,以及与一般健康、睡眠和福祉相关的搜索。为了深入了解公共限制的启动与在线搜索趋势之间的关系,我们评估了六周的时间;“早期大流行时期”(2020年3月1日至2020年4月11日)。为了提供有意义的大流行前比较,对2019年类似时期(2019年3月3日至4月13日)的RSV和中位数差异分析进行了比较。与与更一般的睡眠健康、心理健康和福祉相关的在线搜索相比,EPP与与COVID-19症状相关的在线搜索增加有关。与2019年同期相比,后一种搜索词经常显示,EPP期间RSV下降或变化很小。这一发现说明了COVID-19大流行与在线搜索行为之间的潜在联系,并证实了这一时期有关互联网搜索的现有发现。卫生保健专业人员在未来大流行期间进行主动沟通,并作为一项持续措施,有助于防止公众忽视一般健康和福祉症状,并鼓励报告和早期干预。
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引用次数: 4
Prevalence, incidence, and characteristics of CPAP treated OSA patients with residual excessive daytime sleepiness, as indicated by health-related data – A population representative study 健康相关数据表明,CPAP治疗OSA患者白天过度嗜睡残留的患病率、发病率和特征——一项人群代表性研究
Pub Date : 2022-12-01 DOI: 10.1016/j.sleepe.2022.100044
Georg Nilius , Ulf Kallweit , Daniel Trümper , Tobias Vogelmann , Tino Schubert

Purpose

Excessive daytime sleepiness (EDS) is a symptom experienced by patients with obstructive sleep apnea (OSA) that may persist despite primary CPAP therapy (residual EDS; rEDS). This study aimed to estimate the age- and gender-specific prevalence and incidence for CPAP-treated OSA patients that showed indicators of rEDS in health-related data.

Methods

This study used the InGef research database, an anonymized representative dataset of 4 million persons covered by statutory health insurance in Germany. OSA patients receiving CPAP therapy were analyzed and data indicators for rEDS, or with EDS not satisfactorily treated by primary OSA therapy, were identified using an expert-opinion based diagnostic scheme in two study cohorts: The objective of the first cohort was to estimate the 12-month prevalence and incidence of rEDS in OSA (study period: 2016). The second cohort investigates patient characteristics and health care utilization (study period: 2013–2018).

Results

1298 OSA patients with indicators of rEDS after initiation of CPAP therapy were identified, giving an overall prevalence estimate of 41.1 (95%-CI 38.9-43.4) per 100,000 persons in Germany. Of all CPAP-users, 6.4% were affected by rEDS. Annual incidence was estimated to be 6.4 (95%-CI 5.6-7.4) per 100,000 persons. In the year before CPAP treatment started, 46% received antidepressants, 45% were in psychotherapeutic treatment and 58% of employees were unable to work, on average for 71 days within one year.

Conclusion

Patients that were identified with indicators of residual EDS showed a high socioeconomic burden potentially leading to an increased demand of healthcare services and incapacity for work.

目的:白天过度嗜睡(EDS)是阻塞性睡眠呼吸暂停(OSA)患者经历的一种症状,尽管初次CPAP治疗(残余EDS;红色)。本研究旨在估计cpap治疗的OSA患者的年龄和性别特异性患病率和发病率,这些患者在健康相关数据中显示出red指标。方法本研究使用了InGef研究数据库,这是一个匿名的代表性数据集,涵盖了德国400万人的法定健康保险。在两个研究队列中,对接受CPAP治疗的OSA患者进行分析,并使用基于专家意见的诊断方案确定red的数据指标,或原发性OSA治疗不能令人满意的EDS:第一个队列的目的是估计OSA中12个月的red患病率和发病率(研究期间:2016年)。第二组研究患者特征和医疗保健利用情况(研究期:2013-2018)。结果1298例OSA患者在开始CPAP治疗后出现了red指标,在德国的总体患病率估计为每10万人41.1例(95% ci 38.9-43.4)。在所有的cpap用户中,6.4%的人受到了red的影响。年发病率估计为每10万人6.4例(95%可信区间5.6-7.4)。在CPAP治疗开始前一年,46%的员工接受抗抑郁药物治疗,45%的员工接受心理治疗,58%的员工无法工作,一年内平均有71天无法工作。结论残馀EDS患者具有较高的社会经济负担,可能导致医疗服务需求的增加和工作能力的丧失。
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引用次数: 1
Sleep parameters associated with university students’ grade point average and dissatisfaction with academic performance 睡眠参数与大学生平均成绩和学业表现不满意程度的关系
Pub Date : 2022-12-01 DOI: 10.1016/j.sleepe.2022.100038
Sophie Desjardins, Marjorie Grandbois

The present study sought to determine which subjective sleep assessment parameters were most strongly associated with university students’ grade point average (GPA) and level of satisfaction with their academic performance. One hundred and five students completed the Pittsburgh Sleep Quality Index and answered questions about their GPA and level of satisfaction with that average. Logistic regression analyses indicate that the parameters most strongly associated with students’ GPA are, in descending order, sleep efficiency, daytime dysfunction due to sleepiness, and total sleep time. Only one parameter was associated with dissatisfaction with the GPA: subjective sleep quality. This study highlights the importance of considering students’ expectations of their academic performance rather than focusing solely on their grades. It also advocates for promoting high sleep efficiency rather than focusing exclusively or primarily on sleep duration.

本研究试图确定哪些主观睡眠评估参数与大学生的平均绩点(GPA)和学业表现满意度最密切相关。105名学生完成了匹兹堡睡眠质量指数,并回答了有关他们的平均绩点和平均满意度的问题。Logistic回归分析表明,与学生GPA相关度最高的参数依次为睡眠效率、白天困倦导致的功能障碍和总睡眠时间。只有一个参数与对GPA的不满有关:主观睡眠质量。这项研究强调了考虑学生对学业表现的期望而不是仅仅关注他们的成绩的重要性。它还提倡提高睡眠效率,而不是只关注或主要关注睡眠时间。
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引用次数: 1
期刊
Sleep epidemiology
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