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Assessment of complications in third molar surgery performed by resident surgeons: A comprehensive analysis 评估由住院外科医生实施的第三磨牙手术的并发症:综合分析
IF 0.6 Q4 SURGERY Pub Date : 2024-06-28 DOI: 10.1016/j.sipas.2024.100256
João Mendes de Abreu , Érica Cerqueira , Anabela Quitério , Tiago Nunes , José Figueiredo , Ana Corte-Real

Introduction

Third molar extractions present a wide spectrum of reported complications, spanning from 2.6 % to 30.9 %, making it challenging to predict outcomes for individual patients.

This study seeks to evaluate third molar extractions conducted exclusively by stomatology or maxillofacial surgery residents, examining associated complications. Its aim also extends to delineating the related risks concerning epidemiological and clinical factors, juxtaposed against findings in the existing literature.

Materials and methods

An observational prospective cohort study was conducted at the Clinical and Academic Centre of Coimbra, Portugal, from July 2021 to December 2023. Descriptive statistics were used considering the adequate statistical parameters. Inferential statistical analysis was performed using Student's t-test, the Chi-squared test, and Spearman rank correlation to analyze the relationship between study variables. A p-value of less than 0.05 was considered statistically significant.

Results

485 patients underwent third molar extractions performed exclusively by stomatology and maxillofacial surgery residents, comprising a total of 686 extracted teeth and resulting in 71 reported complications (14.6 % per patient and 10.3 % per extracted tooth). Results revealed that patients undergoing lower third molar extraction faced a 3.7 times higher risk of complications compared to those undergoing upper third molar extraction. Teeth categorized as “IIIC” by Pell and Gregory's classification and those undergoing osteotomy and odontosection also exhibited a higher-than-expected complication rate with statistically significant differences being observed. No other variables showed a positive or negative statistically significant correlation with complication occurrence.

Discussion and conclusion

Despite the expectation of a heightened complication rate, this study revealed that a successful and comprehensive training regimen results in encountering complication rates akin to those documented in established literature.

These findings also underscore the importance of recognizing that a resident's surgical accomplishment is intrinsically tied to acknowledging and respecting their learning curve.

导言据报道,第三磨牙拔除术的并发症范围很广,从2.6%到30.9%不等,因此预测个别患者的预后具有挑战性。本研究旨在评估完全由口腔科或颌面外科住院医师进行的第三磨牙拔除术,检查相关并发症。材料与方法2021年7月至2023年12月,在葡萄牙科英布拉临床与学术中心开展了一项前瞻性队列观察研究。研究使用了描述性统计方法,并考虑了适当的统计参数。使用学生 t 检验、卡方检验和斯皮尔曼等级相关性进行推断统计分析,以分析研究变量之间的关系。结果485名患者接受了完全由口腔颌面外科住院医师实施的第三磨牙拔除术,共拔除了686颗牙齿,报告并发症71例(每位患者14.6%,每颗拔除牙齿10.3%)。结果显示,下第三磨牙拔除术患者面临的并发症风险是上第三磨牙拔除术患者的 3.7 倍。根据佩尔和格雷戈里的分类,被归类为 "IIIC "的牙齿以及接受截骨术和牙槽骨切除术的牙齿的并发症发生率也高于预期,并且在统计学上存在显著差异。讨论和结论尽管预期并发症发生率会升高,但本研究表明,成功而全面的培训计划会导致并发症发生率与已有文献记载的并发症发生率相近。这些发现还强调了认识到住院医师的手术成就与承认和尊重其学习曲线有着内在联系的重要性。
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引用次数: 0
The effect of Guided imagery on perioperative anxiety in hospitalized adult patients: A systematic review of randomized controlled trials 引导想象对住院成年患者围手术期焦虑的影响:随机对照试验的系统回顾
IF 0.6 Q4 SURGERY Pub Date : 2024-06-27 DOI: 10.1016/j.sipas.2024.100255
Mahdiyeh Arjmandy Anamagh , Mohammad Shafiei Kouhpayeh , Shahab Khezri , Rasoul Goli , Navid Faraji , Babak Choobi Anzali , Himan Maroofi , Nima Eskandari , Fereshteh Ghahremanzad

Objective

Guided imagery is a relaxation technique that uses mental visualization to help individuals relax and focus their minds. This systematic review examines the effect of guided imagery on perioperative anxiety in hospitalized adult patients. The aim is to provide a comprehensive analysis of the existing evidence on the efficacy of guided imagery as an intervention for reducing perioperative anxiety.

Methods

A systematic search was conducted on databases including Web of Science, PubMed, Scopus, and PsycINFO. After screening titles and abstracts, full-text articles were assessed for eligibility. The selected studies were analyzed for their findings related to the effect of guided imagery on perioperative anxiety in adult patients.

Results

Nine studies met the inclusion criteria and provided sufficient data for analysis. The majority of the included studies reported a statistically significant reduction in perioperative anxiety following guided imagery interventions. The variations in intervention protocols, such as the content, duration, and frequency of guided imagery, were observed across the studies. Patient satisfaction and acceptance of guided imagery interventions were generally high.

Conclusion

The findings of this systematic review suggest that guided imagery is an effective intervention for reducing perioperative anxiety in hospitalized adult patients. Despite the limitations of small sample sizes and variability in measurement tools, the consistent positive results and high patient satisfaction indicate the potential benefits of incorporating guided imagery into perioperative care protocols. More comprehensive research with bigger samples and standardized tools is essential for guiding imagery integration in clinical practice.

目的引导想象是一种放松技巧,它利用心理可视化来帮助人们放松和集中注意力。本系统综述研究了引导想象对住院成年患者围手术期焦虑的影响。方法在 Web of Science、PubMed、Scopus 和 PsycINFO 等数据库中进行了系统检索。在筛选了标题和摘要后,对全文进行了资格评估。结果9项研究符合纳入标准,并提供了足够的数据用于分析。所纳入的大多数研究报告称,在引导想象干预后,围手术期焦虑症在统计学上有明显减轻。各项研究的干预方案存在差异,如引导想象的内容、持续时间和频率。患者对引导式意象干预的满意度和接受度普遍较高。 结论:本系统综述的研究结果表明,引导式意象是减少住院成年患者围手术期焦虑的有效干预方法。尽管存在样本量小和测量工具不同的局限性,但一致的积极结果和较高的患者满意度表明,将引导式意象疗法纳入围手术期护理方案具有潜在的益处。使用更大样本和标准化工具进行更全面的研究对于指导将意象疗法纳入临床实践至关重要。
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引用次数: 0
Predictors of postoperative complications following thyroidectomy: A systematic review 甲状腺切除术后并发症的预测因素:系统回顾
Q4 SURGERY Pub Date : 2024-06-13 DOI: 10.1016/j.sipas.2024.100252
Philip KW Hong , Aman Pathak , Aditya S Shirali

Introduction

Thyroidectomy is considered a relatively safe procedure with a low risk of postoperative complications, making it challenging to identify predictors of complications to improve shared decision making. Recent advancements in clinical bioinformatics and surgical decision-making tools have the potential to improve patient outcomes. This systematic review aimed to assess the current understanding of factors predicting such complications following thyroidectomy.

Methods

We searched PubMed/MEDLINE, Web of Science, and EMBASE for studies published between 2010 and October 2023, investigating predictors of postoperative complications after thyroidectomy. Studies were included if they investigated predictors of hypocalcemia, hypoparathyroidism, vocal cord paresis (VCP), hematoma, or other postoperative complications. Studies solely reliant on univariate and ROC analyses were excluded. Independent predictors of each postoperative complication were evaluated and categorized as biochemical, surgical, and patient/disease specific.

Results

Forty-five studies were included. Biochemical hypocalcemia and transient hypoparathyroidism were the most investigated complications, with reported rates ranging from 15.7 % to 76.7 % and 12.9 % to 53.8 %, respectively. The majority of studies (n = 35, 77 %) focused on these complications. Biochemical markers (e.g., serum calcium, parathyroid hormone) were the most frequent predictors identified for these complications. Surgical factors (inadvertent parathyroidectomy) were frequently studied for all complications. Age, gender, and thyroid pathology were common patient/disease-specific predictors.

Conclusion

This review highlights the disparity in research on complication predictors. Most studies focused on hypocalcemia and hypoparathyroidism, with fewer examining VCP, hematoma, and mortality. Notably, a lack of high-quality evidence exists due to the scarcity of prospective and randomized controlled trials. Future research should explore incorporating a wider range of independent predictors, especially surgical factors, into comprehensive predictive models. This review can serve as a foundation for developing such models to improve risk prediction for a broader spectrum of thyroidectomy complications.

导言甲状腺切除术被认为是一种相对安全的手术,术后并发症风险较低,因此确定并发症的预测因素以改善共同决策具有挑战性。临床生物信息学和手术决策工具的最新进展有望改善患者的预后。本系统性综述旨在评估目前对甲状腺切除术后并发症预测因素的理解。方法我们检索了PubMed/MEDLINE、Web of Science和EMBASE上发表的2010年至2023年10月间调查甲状腺切除术后并发症预测因素的研究。只要研究了低钙血症、甲状旁腺功能减退、声带麻痹(VCP)、血肿或其他术后并发症的预测因素,均被纳入研究范围。仅依赖于单变量分析和 ROC 分析的研究被排除在外。对每种术后并发症的独立预测因素进行了评估,并将其分为生化、手术和患者/疾病特异性预测因素。生化性低钙血症和一过性甲状旁腺功能减退症是调查最多的并发症,报告的发生率分别为 15.7% 至 76.7% 和 12.9% 至 53.8%。大多数研究(35 项,77%)都集中在这些并发症上。生化指标(如血清钙、甲状旁腺激素)是这些并发症最常见的预测因素。手术因素(甲状旁腺切除术不慎)是所有并发症的常见研究因素。年龄、性别和甲状腺病理是常见的患者/疾病特异性预测因素。大多数研究侧重于低钙血症和甲状旁腺功能减退症,而较少研究VCP、血肿和死亡率。值得注意的是,由于缺乏前瞻性和随机对照试验,因此缺乏高质量的证据。未来的研究应探索将更广泛的独立预测因素(尤其是手术因素)纳入综合预测模型。本综述可作为开发此类模型的基础,以改善对更广泛的甲状腺切除术并发症的风险预测。
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引用次数: 0
Resident level is associated with operative time in laparoscopic cholecystectomy 住院医师水平与腹腔镜胆囊切除术的手术时间有关
Q4 SURGERY Pub Date : 2024-06-01 DOI: 10.1016/j.sipas.2024.100251
Nada Lelovic , Rebecca Reif , Hanna Jensen , Adria Abella Villafranca , Mary Katherine Kimbrough , Kevin Sexton

Background

While previous literature has shown that resident involvement increases operative time, the influence of resident involvement on operative time is generally not considered in current methods of case time predictions or operating room planning. Furthermore, evidence of prolonged case times based on the level of the assisting resident is yet scarce. We hypothesized that operative time would increase with the post-graduate year of assisting residents as they gain more autonomy in the operating room.

Study design

This was an observational cohort study in which we retrospectively analyzed 802 laparoscopic cholecystectomy cases performed in a single academic institution between May 2014 and December 2020. Only cases in which a Post Graduate Year 1 to 5 (PGY) resident was assisting were included.

Results

PGY1–4 residents had statistically significant positive time coefficient results in all linear regression models, except PGY2s in urgent cases. PGY-2 residents had the longest overall average case time of 98 min. Emergent cases were more likely to have prolonged case times.

Conclusions

The increased average case time associated with PGY-2 residents is likely due to a new level of increased autonomy in the operating room (OR) during this year of training. The linear regression results indicated PGY1–4 residents were more likely to have longer laparoscopic cholecystectomy operative times than the PGY5 residents, except PGY2s in urgent cases. This may reflect the accumulation of surgical skills at the PGY5 level. Resident involvement should be considered in the prediction of operative time in an academic setting.

背景虽然以往的文献表明住院医师的参与会增加手术时间,但在目前的病例时间预测或手术室规划方法中,住院医师的参与对手术时间的影响通常并未被考虑在内。此外,根据协助住院医师的水平而延长病例时间的证据还很少。研究设计这是一项观察性队列研究,我们回顾性分析了 2014 年 5 月至 2020 年 12 月期间在一家学术机构进行的 802 例腹腔镜胆囊切除术病例。研究结果PGY1-4住院医师在所有线性回归模型中的时间系数结果均为统计学意义上的正数,但PGY2住院医师在急诊病例中除外。PGY2 级住院医师的病例总平均用时最长,为 98 分钟。结论PGY-2住院医师的平均病例时间增加可能是由于在这一年的培训中,手术室(OR)的自主性提高到了一个新的水平。线性回归结果显示,与 PGY5 住院医师相比,PGY1-4 住院医师的腹腔镜胆囊切除术手术时间更长,但 PGY2 住院医师的紧急病例除外。这可能反映了住院医师在 PGY5 阶段所积累的手术技能。在学术环境中预测手术时间时应考虑住院医师的参与。
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引用次数: 0
Marital status shows no protective effect on perioperative outcomes after robotic-assisted pulmonary lobectomy 婚姻状况对机器人辅助肺叶切除术的围手术期结果没有保护作用
Q4 SURGERY Pub Date : 2024-04-26 DOI: 10.1016/j.sipas.2024.100250
Jenna C. Marek , Allison O. Dumitriu Carcoana , William J. West III , Emily E. Weeden , Ajay Varadhan , Jessica Cobb , Sarah Cool , Gregory Fishberger , Collin B. Chase , Maykel Dolorit , Harrison E. Strang , Carla C. Moodie , Joseph R. Garrett , Jenna R. Tew , Jobelle Joyce-Anne R. Baldonado , Jacques P. Fontaine , Eric M. Toloza

Background

Marital status has been shown to have protective effects for married patients with various cancers. We sought to determine effects of marital status on perioperative outcomes after robotic-assisted pulmonary lobectomy (RAPL).

Methods

We retrospectively analyzed 709 consecutive patients who underwent RAPL between 2010 and 2022 by one surgeon. Patients were stratified by marital status at time of surgery. The Married group included married, domestically partnered, and co-habitating patients (N = 473). The Unmarried group included never married, divorced, and widowed individuals (N = 236). Demographics, preoperative comorbidities, intraoperative and postoperative complications, estimated blood loss (EBL), chest tube duration, hospital length of stay (LOS), tumor characteristics, and survival data were analyzed utilizing Student's t-test, Wilcoxon rank-sum test, Chi-square, or Fisher's exact test as appropriate, with significance at p0.05.

Results

Unmarried patients were more likely to be female, while married patients were more likely to experience robotic-associated intraoperative complications and greater intraoperative estimated blood loss. Kaplan-Meier survival analysis revealed no difference in 5-year overall survival based on marital status. Other perioperative outcomes, intraoperative complications (except robotic-associated), postoperative complications, demographic history (except gender), and preoperative comorbidities did not significantly differ between the two groups.

Conclusion

This study challenges the existing reports in the literature that marriage confers cancer treatment outcomes advantage and prolonged survival among cancer patients. Social support, in terms of a spouse or domestic partner, may be less protective in early-stage lung cancer and after minimally invasive pulmonary lobectomy compared to other cancer populations.

背景婚姻状况已被证明对已婚的各种癌症患者具有保护作用。我们试图确定婚姻状况对机器人辅助肺叶切除术(RAPL)围术期结果的影响。方法 我们回顾性分析了 2010 年至 2022 年间由一名外科医生进行 RAPL 手术的 709 名连续患者。根据手术时的婚姻状况对患者进行分层。已婚组包括已婚、同居和同居患者(N = 473)。未婚组包括从未结婚、离婚和丧偶的患者(N = 236)。人口统计学、术前并发症、术中和术后并发症、估计失血量(EBL)、胸腔插管时间、住院时间(LOS)、肿瘤特征和生存数据均采用学生 t 检验、Wilcoxon 秩和检验、卡方检验或费雪精确检验进行分析,显著性检验(P≤0.05)。05.Results 未婚患者更可能是女性,而已婚患者更可能出现机器人相关的术中并发症和更大的术中估计失血量。Kaplan-Meier生存分析显示,婚姻状况对5年总生存率没有影响。其他围手术期结果、术中并发症(机器人相关并发症除外)、术后并发症、人口统计学史(性别除外)以及术前合并症在两组之间没有显著差异。与其他癌症患者相比,配偶或家庭伴侣的社会支持对早期肺癌和微创肺叶切除术后患者的保护作用可能较弱。
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引用次数: 0
Evaluation of racial/ethnic disparities in surgical outcomes after rectal cancer resection: An ACS-NSQIP analysis 评估直肠癌切除术后手术效果的种族/民族差异:ACS-NSQIP 分析
Q4 SURGERY Pub Date : 2024-04-17 DOI: 10.1016/j.sipas.2024.100248
Carolina Vigna, Ana Sofia Ore, Anne Fabrizio, Evangelos Messaris

Background

Disparities exist the management of rectal cancer. We sought to evaluate short-term surgical outcomes among different racial/ethnic groups following rectal cancer resection.

Materials and Methods

National Surgical Quality Improvement Program (NSQIP) database (2016–2019) was queried. Patients undergoing rectal cancer resection were categorized by race/ethnicity. Circumferential resection margin positivity rate and postoperative outcomes were evaluated. 1:1 Propensity score matching (PSM) was used.

Results

Of 1,753 patients, 80.2 % were White, 7.6 % Black, 8.5 % Asian and 3.7 % Hispanic. On unadjusted analysis, Hispanic patients presented longer operative time(p = 0.029), and Black patients higher postoperative ileus(p = 0.003) and readmission(p = 0.023) rates. After PSM, Hispanics had a significantly higher circumferential resection margin positivity rate(p = 0.032), Black patients higher postoperative ileus rate(p = 0.014) and longer LOS(p = 0.0118) when compared to White counterparts.

Conclusion

Racial disparities were found in short-term postoperative outcomes. Hispanic patients presented higher margin positivity rate and Black patients worst 30-day postoperative outcomes. Comparative studies evaluating trends and a higher number of minority patients included in databases are warranted.

背景直肠癌的治疗存在差异。我们试图评估不同种族/族裔群体在直肠癌切除术后的短期手术效果。材料与方法查询了国家外科质量改进计划(NSQIP)数据库(2016-2019 年)。按种族/民族对接受直肠癌切除术的患者进行分类。对环形切除边缘阳性率和术后结果进行了评估。结果 在1753名患者中,白人占80.2%,黑人占7.6%,亚裔占8.5%,西班牙裔占3.7%。在未经调整的分析中,西班牙裔患者的手术时间更长(p = 0.029),黑人患者的术后回肠梗阻(p = 0.003)和再入院(p = 0.023)率更高。在 PSM 术后,与白人患者相比,西班牙裔患者的周缘切除边缘阳性率明显更高(p = 0.032),黑人患者的术后回肠率更高(p = 0.014),住院时间更长(p = 0.0118)。西班牙裔患者的边缘阳性率较高,黑人患者的术后 30 天预后最差。有必要进行比较研究,评估趋势并将更多的少数族裔患者纳入数据库。
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引用次数: 0
The pulmonary contusion score: Development of a simple scoring system for blunt lung injury 肺挫伤评分:开发钝性肺损伤的简易评分系统
Q4 SURGERY Pub Date : 2024-04-16 DOI: 10.1016/j.sipas.2024.100247
Lisa J. Toelle , Allison G. McNickle , Declan Feery , Salman Mohammed , Paul J. Chestovich , Kavita Batra , Douglas R. Fraser

Background

Pulmonary contusions (PC) are common after blunt chest trauma and can be identified with computed tomography (CT). Complex scoring systems for grading PC exist, however recent scoring systems rely on computer-generated algorithms that are not readily available at all hospitals. We developed a scoring system for grading PC to predict the need for prolonged mechanical ventilation and initial hospital admission location.

Methods

A retrospective review was performed of adult blunt trauma patients with PC identified on initial chest CT during 2020. Data elements related to demographics, injury characteristics, disposition and healthcare utilization were extracted. The primary outcome was the need for mechanical ventilation for greater than 48 h. A novel scoring system, the Pulmonary Contusion Score (PCS) was developed. The maximum score was 10, with each lobe contributing up to 2 points. A score of 0 was given for no contusion present in the lobe, 1 for less than 50 % contusion, and 2 for greater than 50 % contusion. A PCS of 4 was hypothesized to correlate with need for mechanical ventilation for over 48 h. A confusion matrix of the scoring algorithm was created, and inter-rater concordance was calculated from a randomly selected 125 patients.

Results

A total of 217 patients were identified. 118 patients (54 %) were admitted to the ICU, but only 23 patients (19 %) were intubated, and only 17 patients (8 %) required mechanical ventilation > 48 h. Sensitivity of the scoring system was 20 %, while specificity was 93 %. Negative predictive value was 93 %. Inter-rater agreement was 77 %.

Conclusion

The PCS is a scoring system with high specificity and negative predictive value that can be used to evaluate the need for mechanical ventilation after sustaining blunt PC and can help properly allocate hospital resources.

Level of evidence

IV - diagnostic criteria

背景肺挫伤(PC)是钝性胸部创伤后的常见病,可通过计算机断层扫描(CT)确定。目前已有复杂的PC分级评分系统,但最新的评分系统依赖于计算机生成的算法,并非所有医院都能使用。我们开发了一套用于对 PC 进行分级的评分系统,以预测对长期机械通气的需求和最初的入院位置。方法我们对 2020 年期间在最初的胸部 CT 中发现 PC 的成人钝性创伤患者进行了回顾性审查。提取了与人口统计学、损伤特征、处置和医疗保健利用相关的数据元素。主要结果是需要机械通气超过 48 小时。最高分为 10 分,每个肺叶最多得 2 分。肺叶无挫伤得 0 分,肺叶挫伤少于 50% 得 1 分,肺叶挫伤大于 50% 得 2 分。根据假设,PCS 达到 4 分将与需要机械通气超过 48 小时相关。评分系统的灵敏度为 20%,特异度为 93%,阴性预测值为 93%。阴性预测值为 93%。结论 PCS 是一种具有高度特异性和阴性预测值的评分系统,可用于评估钝性 PC 受伤后是否需要机械通气,并有助于合理分配医院资源。
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引用次数: 0
Predicting in-hospital mortality using Elixhauser comorbidity in patients underwent single and multiple coronary artery bypass surgery 利用 Elixhauser 合并症预测接受单支和多支冠状动脉搭桥手术患者的院内死亡率
Q4 SURGERY Pub Date : 2024-04-16 DOI: 10.1016/j.sipas.2024.100246
Renxi Li , Stephen Huddleston

Background

Coronary Artery Bypass Grafting (CABG) is a high-risk surgery. Cardiovascular diseases are strongly associated with comorbidities. This study aimed to assess the prediction of in-hospital mortality by comorbidities in patients who underwent CABG.

Methods

The National Inpatient Sample database was used to extract patients who received 1, 2, 3, and 4+ CABG between Q4 2015 and 2020. Best-fit model by logistic regressions was used to predict in-hospital mortality by Elixhauser Comorbidity Index (ECI). Moreover, age was adjusted in ECI prediction.

Results

There were 190,524, 83,725, 48,147, and 13,540 patients who underwent 1, 2, 3, and 4+ CABG, respectively. In-hospital mortality was best predicted by ECI in 3 CABG (c-statistic = 0.63, 95 % CI = 0.62–0.65), followed by 4+ CABG (c-statistic = 0.63, 95 % CI = 0.60–0.66), 1 CABG (c-statistic = 0.62, 95 % CI = 0.61–0.63), and 2 CABG (c-statistic = 0.62, 95 % CI = 0.61–0.63). After adjusting for age, ECI adequately predicted in-hospital mortality in 4+ CABG (c-statistic = 0.72, 95 % CI = 0.69–0.75) and 3 CABG (c-statistic = 0.69, 95 % CI = 0.68–0.71). Predictive powers for age-adjusted ECI were comparable in 1 CABG (c-statistic=0.67, 95 % CI = 0.66–0.68) and 2 CABG (c-statistic = 0.67, 95 % CI = 0.65–0.68).

Conclusions

ECI was a moderate (c-statistic 0.6–0.7) predictor of in-hospital mortality in all CABG. Age-adjusted ECI could effectively predict in-hospital mortality, especially in patients who underwent 3 and 4+ CABG.

背景冠状动脉旁路移植术(CABG)是一种高风险手术。心血管疾病与合并症密切相关。本研究旨在评估合并症对接受 CABG 患者院内死亡率的预测。方法使用全国住院患者抽样数据库,提取 2015 年第四季度至 2020 年期间接受 1、2、3 和 4+ CABG 的患者。采用逻辑回归的最佳拟合模型,通过艾利克肖瑟疾病指数(ECI)预测院内死亡率。结果接受 1、2、3 和 4+ CABG 的患者人数分别为 190524、83725、48147 和 13540 人。在 3 次 CABG(c-统计量 = 0.63,95 % CI = 0.62-0.65)、4 次以上 CABG(c-统计量 = 0.63,95 % CI = 0.60-0.66)、1 次 CABG(c-统计量 = 0.62,95 % CI = 0.61-0.63)和 2 次 CABG(c-统计量 = 0.62,95 % CI = 0.61-0.63)中,ECI 对院内死亡率的预测效果最佳。对年龄进行调整后,ECI 可充分预测 4+ CABG(c-统计量 = 0.72,95 % CI = 0.69-0.75)和 3 CABG(c-统计量 = 0.69,95 % CI = 0.68-0.71)的院内死亡率。在 1 次 CABG(c-统计量=0.67,95% CI = 0.66-0.68)和 2 次 CABG(c-统计量=0.67,95% CI = 0.65-0.68)中,年龄调整后 ECI 的预测能力相当。年龄调整后的ECI可有效预测院内死亡率,尤其是接受3次和4次以上CABG的患者。
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引用次数: 0
Indications and outcomes of liver transplantation for liver tumors in the United States 美国肝脏肿瘤肝移植的适应症和结果
Q4 SURGERY Pub Date : 2024-04-04 DOI: 10.1016/j.sipas.2024.100245
Kenji Okumura, Abhay Dhand, Kamil Hanna, Ryosuke Misawa, Hiroshi Sogawa, Gregory Veillette, Seigo Nishida

Background

While hepatocellular carcinoma (HCC) remains the leading cause of liver transplant (LT) for liver tumors, indications have broadened over the years. Data regarding patient characteristics and outcomes of LT for liver tumors are limited.

Methods

From Jan-2002 to March-2022, 14,406 LT recipients for various liver tumors were identified in United Network for Organ Sharing database. Overall post-transplant survival analysis was performed with Kaplan-Meier method and multivariable Cox proportional-hazards model.

Results

During the study period, indications for LT for various hepatic tumors were HCC (88.5 %), benign tumors (5.1 %), cholangiocarcinoma (3.9 %), angiosarcoma (0.7 %), bile duct cancer (0.7 %), secondary tumors (0.5 %) and others (0.7 %). Compared to non-HCC, LT recipients for HCC were older (median age 61 vs 54 years, P < 0.001), more often male (77% vs 48 %, P < 0.001), more often Hispanic (16% vs 8.0 %), had higher BMI (28.2 vs 25.3, P < 0.001) and higher prevalence of Hepatitis C (53% vs 3.9 %, P < 0.001). Donor characteristics across various groups were similar. One-year survival in LT recipients of HCC was higher (HCC: 91.7% vs. non-HCC: 90.3 %) with adjusted Hazard Ratio (aHR) of 0.87; 95 % CI 0.77–0.99, P = 0.033 in a multivariable Cox regression analysis. Compared to HCC, survival outcomes were worse in cholangiocarcinoma (aHR 1.70; 95 %CI 1.43–2.01, P < 0.001), bile duct cancer (aHR 3.03; 95 %CI 2.12–4.33, P < 0.001), secondary tumors including colon cancer and neuroendocrine tumors (aHR 1.88; 95 % CI 1.24–2.85, P = 0.003), with best survival in patients with benign tumors (aHR 0.57; 95 %CI 0.46–0.70, P < 0.001).

Conclusions

LT is performed for various liver tumors with variable outcomes among these primary indications.

背景虽然肝细胞癌(HCC)仍是肝脏肿瘤肝移植(LT)的主要病因,但多年来适应症已有所扩大。方法从2002年1月至2022年3月,器官共享联合网络数据库共收集了14406例因各种肝脏肿瘤接受肝移植的患者。结果在研究期间,各种肝肿瘤的LT适应症为HCC(88.5%)、良性肿瘤(5.1%)、胆管癌(3.9%)、血管肉瘤(0.7%)、胆管癌(0.7%)、继发性肿瘤(0.5%)和其他(0.7%)。与非 HCC 相比,HCC 的 LT 受体年龄更大(中位年龄 61 岁对 54 岁,P < 0.001),男性更多(77% 对 48%,P < 0.001),西班牙裔更多(16% 对 8.0%),体重指数更高(28.2 对 25.3,P < 0.001),丙型肝炎患病率更高(53% 对 3.9%,P < 0.001)。各组别的供体特征相似。在多变量考克斯回归分析中,HCC LT受者的一年生存率更高(HCC:91.7% vs. 非HCC:90.3%),调整后危险比(aHR)为0.87;95 % CI 0.77-0.99,P = 0.033。与 HCC 相比,胆管癌(aHR 1.70; 95 %CI 1.43-2.01,P <0.001)、胆管癌(aHR 3.03; 95 %CI 2.12-4.33,P <0.001)、包括结肠癌和神经内分泌肿瘤在内的继发性肿瘤(aHR 1.88;95 %CI 1.24-2.85,P = 0.003),良性肿瘤患者的生存率最高(aHR 0.57;95 %CI 0.46-0.70,P <;0.001)。
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引用次数: 0
Surgical risks and care trends: A cross sectional study of people experiencing homelessness presenting at a free clinic care in Miami-Dade County 手术风险和护理趋势:对迈阿密-戴德县免费诊所就诊的无家可归者的横断面研究
Q4 SURGERY Pub Date : 2024-04-02 DOI: 10.1016/j.sipas.2024.100244
Shivangi Parmar , Emily Eachus , Orly Morgan , Boris Yang , Violet Victoria , Suhas Seshadri , Armen Henderson , Stefan Kenel-Pierre , Joshua Laban

Background

The effects of housing insecurity on surgical care are under researched and largely unknown. Thus far, studies on surgery outcomes of people experiencing homelessness either focus on shelter-based patients or do not differentiate whether patients are sheltered or unsheltered, despite significant differences in care needs and health risks. Herein we provide the first report on surgical care trends of people experiencing unsheltered homelessness.

Methods

Clinical history, medication list, and blood pressure records of 300 people experiencing unsheltered homelessness receiving care at a free mobile clinic were deidentified, downloaded and analyzed in R studio 4.3.0. Participants were asked whether they had undergone surgery and included surgical history for those who had.

Results

Of 300 participants, 18 % (N = 55) had a history of surgery, most common being 1) orthopedics (N = 20), 2) vascular (N = 18), 3) general (N = 6), 4) acute trauma response (N = 5), 5) ophthalmology (N = 4), 6) surgical oncology (N = 2). Post-discharge, 13 % returned with wound site infections and 9 % were readmitted for treatment. Chi Square test showed Hypertension [X2 (1, n = 300)=10.9, p < 0.001] and Type II Diabetes [X2 (1, n = 300)=10.5, p = 0.0012] significantly increased likelihood of needing vascular surgery, particularly lower extremity wound debridement or amputation.

Conclusion

Little research has been done assessing surgical care trends for people experiencing unsheltered homelessness. Results indicate possible presence of barriers accessing cancer care and increased risk for vascular disease needing surgical intervention. Future research is needed to understand, address, and overcome current surgical care barriers to help this at-risk and underserved community.

背景住房不安全对外科护理的影响研究不足,而且在很大程度上不为人所知。迄今为止,有关无家可归者手术效果的研究要么集中在以庇护所为基础的病人身上,要么不区分病人是有庇护所的还是无庇护所的,尽管在护理需求和健康风险方面存在显著差异。方法对在免费流动诊所接受治疗的 300 名无家可归者的临床病史、药物清单和血压记录进行去身份化处理,并在 R studio 4.3.0 中下载和分析。结果 在 300 名参与者中,18%(N = 55)有手术史,最常见的手术有:1)骨科(N = 20);2)血管科(N = 18);3)普外科(N = 6);4)急性创伤反应科(N = 5);5)眼科(N = 4);6)肿瘤外科(N = 2)。出院后,13% 的患者因伤口感染返回医院,9% 的患者再次入院接受治疗。Chi Square检验显示,高血压[X2 (1, n = 300)=10.9, p < 0.001]和II型糖尿病[X2 (1, n = 300)=10.5, p = 0.0012]显著增加了需要血管手术的可能性,尤其是下肢伤口清创或截肢。研究结果表明,无家可归者在获得癌症治疗方面可能存在障碍,而且需要外科手术治疗的血管疾病风险增加。未来的研究需要了解、解决和克服当前的外科护理障碍,以帮助这个高危和服务不足的群体。
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引用次数: 0
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Surgery in practice and science
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