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The Influence of Thyroid Hormones on Levels of Lipid Profile and Adipokine in Iraqi Women with Thyroid Disorders 甲状腺激素对伊拉克甲状腺疾病妇女血脂和脂肪因子水平的影响
Pub Date : 2023-09-01 DOI: 10.22401/anjs.26.3.02
Kawther A. Abd, Alaa Hussein J. AL-Qaisi, Nany Hairunisa
Hypothyroidism and hyperthyroidism are prevalent endocrine diseases.These have significant implications for lipid synthesis, mobilization, and metabolism. Retinol-binding protein 4 is a new adipokine implicated in some physiological and pathological processes, such as metabolic and endocrine disorders. Its elevation aids in the diagnosis of thyroid problems. The present study includes 60 women with thyroid diseases; 30 of them have hypothyroidism and 30 have hyperthyroidism. This study includes 20 healthy women as a control group. For each participant anthropometric, biochemical Thyroid-stimulating hormone, triiodothyronine, Thyroxine, lipid profile, and retinol binding protein-4 are measured. The results show that hypothyroid women have significantly higher levels of total cholesterol, triglycerides, and lowdensity lipoprotein cholesterol as compared to the hyperthyroid or control group. The serum of total cholesterol, triglycerides, and low-density lipoprotein cholesterol are significantly lower in hyperthyroid women compared to the hypothyroid or control group. In addition, there are no significant differences in blood high-density lipoprotein cholesterol concentrations among the three groups. Furthermore, serum retinolbinding protein-4 levels were higher in the hyperthyroid group compared to the hypothyroid or control groups. According to the findings of this study, hypothyroidism causes dyslipidemia, which raises the risk of cardiovascular disease while hyperthyroidism causes abnormalities in lipid profiles. Additionally, hyperthyroidism causes an increase in serum retinol-binding protein-4 levels in the blood.
甲状腺功能减退和甲状腺功能亢进是常见的内分泌疾病。这些对脂质合成、动员和代谢具有重要意义。视黄醇结合蛋白4 (retinol binding protein 4)是一种新的脂肪因子,与代谢和内分泌紊乱等生理病理过程有关。它的升高有助于甲状腺疾病的诊断。本研究包括60名患有甲状腺疾病的妇女;其中30人有甲状腺功能减退30人有甲状腺功能亢进。本研究选取20名健康女性作为对照组。对每个参与者进行人体测量、生化促甲状腺激素、三碘甲状腺原氨酸、甲状腺素、脂质谱和视黄醇结合蛋白-4测量。结果显示,与甲状腺功能亢进或对照组相比,甲状腺功能减退的女性的总胆固醇、甘油三酯和低密度脂蛋白胆固醇水平明显更高。甲状腺功能亢进妇女的血清总胆固醇、甘油三酯和低密度脂蛋白胆固醇明显低于甲状腺功能低下或对照组。此外,三组间血液高密度脂蛋白胆固醇浓度无显著差异。此外,甲状腺功能亢进组的血清视黄醇结合蛋白-4水平高于甲状腺功能低下组或对照组。根据这项研究的结果,甲状腺功能减退会导致血脂异常,从而增加心血管疾病的风险,而甲状腺功能亢进则会导致血脂异常。此外,甲状腺机能亢进导致血液中血清视黄醇结合蛋白-4水平升高。
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引用次数: 0
Assessment of Serum Apelin Level in Iraqi Type 2 Diabetic Nephropathy Patients 伊拉克2型糖尿病肾病患者血清Apelin水平的评估
Pub Date : 2023-09-01 DOI: 10.22401/anjs.26.3.04
Raghad Jwameer, Alaa Hussein J. Alqaisi, Amamer Redwan, Salam Mohammed
The present study is investigated the relationship between Apelin concentration and various biochemical parameters in patients with type2 diabetic nephropathy. A total of 30 patients diagnosed with Diabetic Nephropathy at Al-Yarmouk and Al-Karama teaching hospitals were included in the study and compared to 40 healthy individuals forming the control group. The study was identified a significant increase in Apelin concentration among patients with type 2 diabetic nephropathy, compared to the control group. Additionally, various biochemical parameters were analyzed, and a strong correlation was found between their concentrations and Apelin levels. Considerable elevation of serum nitrogen compounds like urea and creatinine, as well as fasting blood glucose and glycated hemoglobin (HbA1c) were observed in the type 2 diabetic nephropathy patients. A positive correlation between Apelin and both creatinine and glycated hemoglobin levels was observed. Conversely, a negative correlation was observed between Apelin and the glomerular filtration rate (GFR), indicating potential implications for kidney function in these patients. These findings emphasize the significance of monitoring Apelin concentration along with other biochemical variables as essential indicators for the management and understanding of type 2 diabetic nephropathy. Further research in type 2 diabetic nephropathy could offer valuable insights into potential interventions and treatment strategies for improving patient outcomes.
本研究探讨2型糖尿病肾病患者Apelin浓度与各项生化指标的关系。共有30名在Al-Yarmouk和Al-Karama教学医院诊断为糖尿病肾病的患者被纳入研究,并与40名健康个体形成对照组。研究发现,与对照组相比,2型糖尿病肾病患者的Apelin浓度显著增加。此外,分析了各种生化参数,发现它们的浓度与Apelin水平有很强的相关性。2型糖尿病肾病患者血清中尿素和肌酐等氮化合物以及空腹血糖和糖化血红蛋白(HbA1c)明显升高。Apelin与肌酐和糖化血红蛋白水平呈正相关。相反,Apelin与肾小球滤过率(GFR)呈负相关,表明对这些患者的肾功能有潜在影响。这些发现强调了监测Apelin浓度以及其他生化变量作为2型糖尿病肾病管理和理解的重要指标的重要性。2型糖尿病肾病的进一步研究可以为改善患者预后的潜在干预和治疗策略提供有价值的见解。
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引用次数: 0
Synthesis New Triethylammonium Salts as Corrosion Inhibitors for Mild Steel in 1 MH2SO4 新型三乙基铵盐在1mh2so4中作为低碳钢缓蚀剂的合成
Pub Date : 2023-06-01 DOI: 10.22401/anjs.26.2.02
Mariam S. Muhsin, Mehdi S. Shihab
Somenewtriethylammoniumsalts,namelytriethylammonium4-(cyclohexyl-amino)-4-oxobut-2-enoate(B1),triethylammonium5-(cyclohexylamino)-5-oxopentanoate(B2),triethylammonium4-(cyclohexylamino)-4-oxobutanoate(B3)weresynthesizedasacorrosioninhibitorformildsteel.Thesesaltscouldtestinonemolaritysulfuricacidatroomtemperaturefor24hoursbyusingweightoflosingmethod.Theresultsrevealedthattheefficiencyofinhibitionofalltriethylammoniumsaltswerehighatthemaximumconcentrationoftriethylammoniumsalt.Theincreaseconcentrationofinhibitorsisassociatedwithdecreasingtherateofcorrosion,buttheincreasingofefficienciesofinhibition,andagreaterdegreeofsurfacecovering.Adsorptionvaluesofthefreeenergywereusedtoillustratetheeffectsofphysisorptionfor(B1,B2,andB3),whichwashelpfulinforecastingthenaturalinteractionbetweenorganiccorrosioninhibitormoleculesandthemetalsurfaceofsteel.
(Somenewtriethylammoniumsalts, namelytriethylammonium4) - cyclohexyl-amino 4-oxobut-2-enoate (B1), triethylammonium5——(cyclohexylamino) 5-oxopentanoate (B2), triethylammonium4——(cyclohexylamino) 4-oxobutanoate weresynthesizedasacorrosioninhibitorformildsteel.Thesesaltscouldtestinonemolaritysulfuricacidatroomtemperaturefor24hoursbyusingweightoflosingmethod.Theresultsrevealedthattheefficiencyofinhibitionofalltriethylammoniumsaltswerehighatthemaximumconcentrationoftriethylammoniumsalt.Theincreaseconcentr (B3)ationofinhibitorsisassociatedwithdecreasingtherateofcorrosion、buttheincreasingofefficienciesofinhibition andagreaterdegreeofsurfacecovering.Adsorptionvaluesofthefreeenergywereusedtoillustratetheeffectsofphysisorptionfor (B1, B2, andB3) whichwashelpfulinforecastingthenaturalinteractionbetweenorganiccorrosioninhibitormoleculesandthemetalsurfaceofsteel。
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引用次数: 0
Thyroid Hormones and Autoantibodies in Iraqi Hyperthyroid Patients 伊拉克甲状腺机能亢进患者的甲状腺激素和自身抗体
Pub Date : 2023-06-01 DOI: 10.22401/anjs.26.2.09
Sarah T. Al-Mofarji, Hameed M. Jasim, Sanad B. Mohammed
Hyperthyroidism can be defined as the status of over production of thyroid hormones: tri-iodothyronine (T3) and thyroxine (T4) as a results of thyroid gland dysfunction. The aim of the current study was to investigate the association between the abnormalities of thyroid hormones (T3 and T4) and serum levels of thyroid auto-antibodies: anti-thyroid peroxidase (TPO-Ab) and anti-thyroid stimulating hormone receptor (TR-Ab) and the state of hyperthyroidism. Blood samples were collected from 75 Iraqi individualswere early diagnosed as hyperthyroidism patients in addition to 25 Iraqi individuals as a healthy control group. Enzyme Linked Fluorescent Assay (ELFA) used to determine the levels of thyroid hormones (T3 and T4) and the level of thyroid stimulating hormone (TSH), Enzyme Linked Immuno-Sorbent Assay (ELISA) was used to determine the levels of auto-antibodies (TPO-Ab and TR-Ab). The results show that T3 levels and T4 levels in hyperthyroidism patients (2.07 nmol/L and 14.02 μg/dl respectively) increased significantly (푃<0.01)compared to healthy control levels (1.33 nmol/L and 6.4 μg/dl respectively). While the levels of thyroid stimulating hormone (TSH) in hyperthyroidism patient (0.17 μIU/Ml) decreased significantly (푃<0.01)when compared with healthycontrol group (1.84 μIU/Ml). The results also showed that levels of TPO-Ab and TR-Ab in hyperthyroidism patients (235.29 IU/mL and 32.05 IU/mL respectively) increased significantly (푃<0.01)when compared to healthy control group (20.76 IU/mL and 0.3 IU/mL respectively). This study revealed that there is an association between thyroid hormones disorders and the positivity of thyroid auto-antibodies in hyperthyroidism patient
甲状腺功能亢进可以定义为甲状腺激素过量产生的状态:三碘甲状腺原氨酸(T3)和甲状腺素(T4)是甲状腺功能障碍的结果。本研究的目的是探讨甲状腺激素(T3和T4)异常与血清甲状腺自身抗体(抗甲状腺过氧化物酶(TPO-Ab)和抗甲状腺刺激激素受体(TR-Ab)水平与甲亢状态的关系。从75名早期诊断为甲状腺功能亢进症的伊拉克人以及25名健康对照组中收集了血液样本。采用酶联荧光法(ELFA)测定甲状腺激素(T3、T4)和促甲状腺激素(TSH)水平,采用酶联免疫吸附法(ELISA)测定自身抗体(TPO-Ab和TR-Ab)水平。结果显示,甲亢患者T3、T4水平(分别为2.07 nmol/L和14.02 μg/dl)较健康对照组(分别为1.33 nmol/L和6.4 μg/dl)显著升高(푃<0.01)。甲亢患者体内促甲状腺激素(TSH)水平(0.17 μIU/Ml)较健康对照组(1.84 μIU/Ml)显著降低(푃<0.01)。甲状腺机能亢进患者TPO-Ab和TR-Ab水平(分别为235.29 IU/mL和32.05 IU/mL)较健康对照组(分别为20.76 IU/mL和0.3 IU/mL)显著升高(푃<0.01)。本研究揭示甲状腺机能亢进患者甲状腺激素紊乱与甲状腺自身抗体阳性之间存在相关性
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引用次数: 0
Evaluation of Some Serum Biochemical Indices in Patients with Gestational Diabetes 妊娠期糖尿病患者血清生化指标的评价
Pub Date : 2023-06-01 DOI: 10.22401/anjs.26.2.01
Marwa A. Hadi, Nawal H. Al-Hashim
The aim of this study was to evaluate some serum biochemical indices in patients with gestational diabetes. Among the study's participants were 100 expectant mothers ranging in age from 24 to 35 who had been diagnosed with diabetes at a maternity hospital or pregnancy center in Baghdad city. According to their previous menstrual cycle or an ultrasound, these ladies were between 28 and 33 weeks pregnant. There were two categories of pregnant women: Twenty pregnant women in good health comprised (control group). Eighty GDM-pregnant women were enrolled. The current results showed a significant increase in levels of glucose, cholesterol, triglyceride, ALT, bilirubin, uric acid, and creatinine in the GDM group as compared with control patients, also a significant decrease in the levels of Albumin, HDL in GDM group as compared with control group. There were no significant differences in the levels of urea and AST in both GDM and control groups. In conclusion, there was a significant increase in levels of glucose, cholesterol, triglyceride, ALT, bilirubin, uric acid, and creatinine in the GDM group.
本研究的目的是评价妊娠期糖尿病患者的一些血清生化指标。该研究的参与者中有100名年龄在24岁至35岁之间的孕妇,她们在巴格达市的妇产医院或怀孕中心被诊断患有糖尿病。根据她们之前的月经周期或超声波检查,这些女性怀孕28至33周。孕妇分为两类:健康状况良好的孕妇共20名(对照组)。80名gdm孕妇被纳入研究。目前的结果显示,GDM组的葡萄糖、胆固醇、甘油三酯、ALT、胆红素、尿酸和肌酐水平与对照组相比显著升高,白蛋白、高密度脂蛋白水平与对照组相比显著降低。GDM组与对照组尿素、AST水平差异无统计学意义。总之,GDM组血糖、胆固醇、甘油三酯、谷丙转氨酶、胆红素、尿酸和肌酐水平显著升高。
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引用次数: 0
Using a Streamlined Procedure to Combine AlCl3 and Chloroacetamide to Create a New Ionic Liquid 用一种简化的程序将AlCl3和氯乙酰胺组合成一种新的离子液体
Pub Date : 2023-06-01 DOI: 10.22401/anjs.26.2.03
Bassam B. Hasan, Taghried A. Salman
By reacting AlCl3 with chloroacetamide (CA) at the optimal mole ratio (2:1), a new type of ionic liquid was created in addition to the group of ionic liquids (aluminum chloride-amide). With an ionic conductivity of 0.34 mS/cm, the resultant clear brown ionic liquid demonstrated good thermal stability at ambient temperature in a glove box filled with nitrogen gas. Its coordination was established using FT-IR. Measurements have been made of additional physical characteristics including viscosity and cyclic voltammetry.
通过AlCl3与氯乙酰胺(CA)以最佳摩尔比(2:1)反应,在离子液体基团(氯化铝-酰胺)之外生成了一种新型离子液体。离子电导率为0.34 mS/cm,在充满氮气的手套箱中表现出良好的热稳定性。利用傅里叶变换红外光谱确定了其协调性。测量了附加的物理特性,包括粘度和循环伏安法。
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引用次数: 0
Recent Studies on Cancer Cell's Inhibition by Organotin (IV) Materials: An Overview 有机锡(IV)材料对癌细胞抑制作用的研究进展
Pub Date : 2023-06-01 DOI: 10.22401/anjs.26.2.04
Falih Ibadi, E. Yousif, M. Al-Mashhadani, N. Hairunisa, Muna Bufaroosh
organotin (IV) compounds have been the focus of recent studies for their potential use in the treatment of cancer. This review provides an overview of recent studies on the inhibition of cancer cells by organotin (IV) materials. The literature suggests that organotin (IV) compounds can selectively target cancer cells and induce apoptosis, making them promising candidates for anticancer drugs. The review covers various types of organotin (IV) compounds, including those containing alkyl, aryl, and amino groups, and their mechanisms of action against cancer cells. Additionally, the study explores the potential toxicity and biocompatibility of these compounds and their derivatives, as well as their potential use in combination therapy. Overall, the results of recent studies suggest that organotin (IV) compounds show great potential for the treatment of cancer. However, more research is needed to fully understand their mechanism of action and potential side effects. The review highlights the need for continued investigation of these compounds and their derivatives to develop effective and safe anticancer therapies
有机锡(IV)化合物因其在治疗癌症方面的潜在用途而成为最近研究的焦点。本文综述了近年来有机锡(IV)材料对癌细胞的抑制作用。文献表明,有机锡(IV)化合物可以选择性靶向癌细胞并诱导细胞凋亡,使其成为抗癌药物的有希望的候选者。综述了各种类型的有机锡(IV)化合物,包括那些含有烷基、芳基和氨基的化合物,以及它们对癌细胞的作用机制。此外,该研究还探讨了这些化合物及其衍生物的潜在毒性和生物相容性,以及它们在联合治疗中的潜在用途。总的来说,最近的研究结果表明,有机锡(IV)化合物在治疗癌症方面显示出巨大的潜力。然而,需要更多的研究来充分了解它们的作用机制和潜在的副作用。这篇综述强调了继续研究这些化合物及其衍生物以开发有效和安全的抗癌疗法的必要性
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引用次数: 0
A Comparative Study of Cyberbullying Detection in Social Media for the Last Five Years 近五年来社交媒体网络欺凌检测的比较研究
Pub Date : 2023-06-01 DOI: 10.22401/anjs.26.2.08
Noor Haydar, Ban N. Dhannoon
The number of users of social media sites has increased nowadays, and while these sites have many benefits, they also have many damages that have grown with the increasing number of users. Among these damages that have spread in social media sites in our time is the phenomenon of cyberbullying. It has become necessary to find solutions to detect it to prevent and hold bullies accountable to reduce the phenomenon of cyberbullying, which has great health and mental effects on the victim in society. There have been many attempts to build models to detect and classify cyberbullying by using machine learning and deep learning algorithms with different sets of data that were collected from social media sites such as Twitter, YouTube, Facebook, Instagram, and others. In this work, we show a group of previous studies that used machine learning and deep learning algorithms in good attempts to detect and classify the phenomenon of cyberbullying.
如今,社交媒体网站的用户数量不断增加,虽然这些网站有很多好处,但随着用户数量的增加,它们也有很多损害。在我们这个时代,在社交媒体网站上传播的这些损害之一是网络欺凌现象。有必要找到解决方案来发现它,防止和追究欺凌者的责任,以减少网络欺凌现象,这对社会受害者的健康和精神影响很大。已经有很多尝试建立模型,通过使用机器学习和深度学习算法,从Twitter、YouTube、Facebook、Instagram等社交媒体网站收集不同的数据集,来检测和分类网络欺凌。在这项工作中,我们展示了一组先前的研究,这些研究使用机器学习和深度学习算法来很好地检测和分类网络欺凌现象。
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引用次数: 1
Best One-Sided Multiplier Approximation by Operators 算子的最佳单侧乘数近似
Pub Date : 2023-06-01 DOI: 10.22401/anjs.26.2.06
Saheb K. Al-Saidy, Naseif J. Al-Jawari, Raad F. Hassan
The aim of studying this research is to find the best one-sided multiplier approximation of unbounded function in 퐿푝,휓푛(푋)−space,푋=[0,1],푝≥1by using type of operators 하푛(푓),픾풏(푓)by means of operators of algebraic polynomials as well as to show the relationship between the multiplier averaged modules of smoothness (휏-modules) and variation of unbounded functions in퐿푝,휓푛(푋)−spac
研究这一研究的目的是找到最好的片面的乘数无界函数的近似퐿푝,휓푛(푋)−空间,푋=[0,1],푝≥1通过使用类型的操作符하푛(푓)픾풏(푓)通过运营商的代数多项式以及显示平滑平均乘法器模块之间的关系(휏模块)和无界函数变化퐿푝,휓푛(푋)−spac
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引用次数: 0
Anatomical Study of Common Maidenhair Fern (Adiantum Capillus-Veneris L) Pteridaceae, in Iraq 伊拉克蕨类科普通毛蕨的解剖学研究
Pub Date : 2023-06-01 DOI: 10.22401/anjs.26.2.10
Abbas M. Ismail, Shaymaa Al-Majmaie
The family Pteridaceae in Iraq comprises 6 species belongs5 genera. These species occur in a diverse range of environments including humid temperate forests, the falls of the waterfalls and shrub lands. The fern species was collected from different locations in environment and geographical habitats during different seasons from two districts in Iraqi Kurdistan. The anatomical structure of the aerial parts were studied. Fronds petiole and rachis (midribe) exhibitY-shaped vascular system, pinnae were di chotomusvenation, and the spores were pyramidal shape. The anatomical characterization of A. capillus-veneris were described with detail for the first time in Iraq
伊拉克蕨类科共有5属6种。这些物种出现在各种不同的环境中,包括湿润的温带森林、瀑布的瀑布和灌木地。在伊拉克库尔德斯坦两个地区不同季节、不同地点的环境和地理生境中采集蕨类植物。对空中部分的解剖结构进行了研究。叶叶柄和轴(中部)呈y形维管系统,耳廓呈双脉化,孢子呈锥体状。本文在伊拉克首次详细地描述了毛囊曲霉的解剖特征
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引用次数: 0
期刊
Al-Nahrain Journal of Science
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