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Third Argentine Consensus statement on management Bipolar Disorders. Section 2 B 关于双相情感障碍管理的第三次阿根廷共识声明。第二节B
Pub Date : 2023-07-10 DOI: 10.53680/vertex.v34i160.459
Marcelo Cetkovich-Bakmas, Andrea Abadi, Sebastián Camino, Gerardo García Bonetto, Luis Herbst, Eliana Marengo, Fernando Torrente, Tomás Maresca, Julián Bustin, Carlos Morra, Ricardo Corral, Daniel Sotelo, Sergio Strejilevich, Julián Pessio, Juan José Vilapriño, Manuel Vilapriño, Gustavo Vázquez, Alejo Corrales

This document constitutes the second section B of the Third Argentine Consensus on the Management of Bipolar Disorders, focused on synthesizing the most updated evidence on therapeutic approaches for adult patients. The scope of this section is to provide therapeutic recommendations for managing bipolar disorders in adults, (i) acute mania (ii) bipolar depression (iii) mixed stated (iv) suicidality and (vi) psychological interventions. In addition, the current manuscript outlines the assessment and management of side effects of pharmacotherapeutic treatments.

本文件是关于双相情感障碍管理的第三次阿根廷共识的第二部分B,重点是综合关于成人患者治疗方法的最新证据。本节的范围是为管理成人双相情感障碍提供治疗建议,(i)急性躁狂(ii)双相抑郁(iii)混合性陈述(iv)自杀和(vi)心理干预。此外,目前的手稿概述了药物治疗的副作用的评估和管理。
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引用次数: 0
The Quality of Violence Risk Formulation and a Quasi-Forensic Mental Health Training Experiment 暴力风险表述质量与准法医心理健康训练实验
Pub Date : 2023-07-10 DOI: 10.53680/vertex.v34i160.457
Débora Moyano, Alejandra Estrada, Arturo Klenner, Adolfo Méndez, Marlene Vidal Quinde, Jorge O Folino

Objectives: The study was aimed at measuring the impact of training on forensic case formulation in mental health and to provide more evidence on the reliability of the TEC-F.

Method: Nine psychiatrists and six psychologists from various Latin American countries participated in a quasi-pedagogical experiment. The quality of formulations was independently and blindly measured pre- and post-intervention with the TEC-F and the assignment of two standard vignettes was also randomly manipulated. Quality mean differences and instrument reliability indicators were calculated.

Results: The values of intraclass correlation coefficients were 0.92; 0.94; 0.83; 0.93 and 0.95 and the values of Cronbach's alpha coefficient were 0.83; 0.94; 0.63; 0.77 and 0.93, for the dimensions transparency, specificity, communication, reasoning and for the total TEC-F respectively. The results of the 19-day test-retest were excellent. The mean TEC-F total quality pre-course was 31.4 and the mean post-course, 38.4 (p = 0.003 and p = 0.001 for group test and paired test respectively).

Conclusions: The pedagogical intervention produced a significant improvement in the quality of the expert’s formulations. The study added evidence supporting the TEC-F reliability.

目的:本研究旨在衡量培训对心理健康法医案例制定的影响,并为TEC-F的可靠性提供更多证据。方法:来自拉丁美洲各国的9名精神科医生和6名心理学家参与了一项准教学实验。在干预前和干预后用TEC-F独立和盲目地测量配方的质量,并对两个标准小插曲的分配进行随机操作。计算质量均值差和仪器可靠性指标。结果:类内相关系数为0.92;0.94;0.83;分别为0.93和0.95,Cronbach’s alpha系数为0.83;0.94;0.63;透明度、特异性、沟通、推理维度和总TEC-F维度分别为0.77和0.93。19天的复检结果非常好。治疗前TEC-F总质量均值为31.4,治疗后TEC-F总质量均值为38.4(组检验p = 0.003,成对检验p = 0.001)。结论:教学干预显著提高了专家配方的质量。该研究增加了支持TEC-F可靠性的证据。
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引用次数: 0
50 Years After Schizophrenia and Cyclothymia, Results and Problems 精神分裂症和循环精神障碍50年后,结果和问题
Pub Date : 2023-07-10 DOI: 10.53680/vertex.v34i160.466
Norberto A Conti
Análisis del libro: Esquizofrenia y Ciclotimia, resultados y problemas, Comp. Gerd Huber, Ed. Morata, Madrid, 1972.
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引用次数: 0
Nuclear energy in the era of climate resilience: advancing long-term scenarios with the world-times model 气候适应时代的核能:用世界时间模型推进长期情景
Pub Date : 2023-06-30 DOI: 10.35335/eeqhzn35
Fankhauser Doyle Edenhofer, Lehtveer Loulou Parikh, S. Yu
Sustainable energy routes that improve climate resilience are needed because climate change affects global energy systems. Nuclear energy's low-carbon electricity could mitigate climate change. This study uses the World-TIMES Model to assess its climatic resilience. A mathematical optimization model is used to discover the best energy mix, including nuclear power, to minimize greenhouse gas emissions and meet energy demand and cost limitations. We use a simplified numerical example to demonstrate the concept and assess nuclear energy, renewable sources, and cost-effectiveness trade-offs. Wind and solar electricity are better in the scenario, reducing greenhouse gas emissions and mitigating climate change. This conclusion is scenario-specific, and real-world difficulties demand more thorough models. Thus, the study emphasizes regional-specific data, dynamic dynamics, and sensitivity analysis. This work improves our understanding of nuclear energy's potential in climate-resilient energy systems and aids policymakers in developing evidence-based energy strategies. The report also emphasizes the importance of renewable energy sources in reaching climate targets and urges future research to solve real-world difficulties and maximize nuclear energy integration in long-term energy planning
由于气候变化影响到全球能源系统,因此需要改善气候适应能力的可持续能源路线。核能的低碳电力可以缓解气候变化。这项研究使用World-TIMES模型来评估其气候适应能力。使用数学优化模型来发现包括核电在内的最佳能源结构,以最大限度地减少温室气体排放,满足能源需求和成本限制。我们使用一个简化的数值示例来演示概念并评估核能,可再生能源和成本效益权衡。在这种情况下,风能和太阳能发电更好,可以减少温室气体排放,减缓气候变化。这个结论是特定于场景的,现实世界的困难需要更彻底的模型。因此,本研究强调区域数据、动态动态和敏感性分析。这项工作增进了我们对核能在气候适应型能源系统中的潜力的理解,并有助于决策者制定基于证据的能源战略。该报告还强调了可再生能源在实现气候目标方面的重要性,并敦促未来的研究解决现实世界的困难,并在长期能源规划中最大限度地利用核能
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引用次数: 0
Advanced integration of stereotaxis and real-time MRI for precise and safe medical navigation: a future paradigm for minimally invasive interventions 立体定向和实时MRI的先进整合,用于精确和安全的医疗导航:微创干预的未来范例
Pub Date : 2023-06-30 DOI: 10.35335/x5n5be87
Lorenzo Söderholm Raygo, Wojcieszynski Puder Tonutti
Minimally invasive techniques have transformed medicine by improving patient outcomes and reducing invasiveness. Existing navigation methods, which use fluoroscopy or pre-operative imaging, lack real-time visualization and precision during complex surgeries. Fluoroscopy may also expose patients and medical staff to ionizing radiation. We propose enhanced stereotaxis and real-time magnetic resonance imaging (MRI) integration to overcome these problems and improve minimally invasive intervention precision and safety. Stereotactic guiding and high-resolution real-time MRI imaging are combined in this research to improve medical navigation. The conceptual framework includes modeling the stereotactic system's magnetic field, real-time tracking of magnetic-sensored medical devices, and dynamic MRI imaging for continuous visibility throughout treatments. Stereotactic and MRI data can be fused for simultaneous vision and navigation, and adaptive path planning algorithms allow real-time targeting and avoidance of key structures. A simulated cardiac electrophysiology catheter ablation treatment shows the combined approach's potential benefits. Real-time adaptive navigation reduces radiation exposure and problems while targeting precisely. This research establishes a new medical navigation paradigm that improves precision, patient safety, and radiation exposure. This integrated method could revolutionize minimally invasive procedures across medical disciplines, despite limitations in patient-specific data integration and real-time algorithm development. This new navigation approach needs further research, validation, and clinical trials to confirm its feasibility and efficacy and improve medical patient care
微创技术通过改善病人的治疗效果和减少侵入性改变了医学。现有的导航方法,使用透视或术前成像,在复杂的手术中缺乏实时可视化和精度。透视也可能使病人和医务人员暴露在电离辐射中。我们提出增强立体定向和实时磁共振成像(MRI)集成来克服这些问题,提高微创介入的精度和安全性。本研究将立体定向和高分辨率实时MRI成像相结合,以改善医疗导航。概念框架包括立体定向系统的磁场建模,磁传感医疗设备的实时跟踪,以及在整个治疗过程中持续可见的动态MRI成像。立体定向和MRI数据可以融合在一起,同时实现视觉和导航,自适应路径规划算法允许实时定位和避开关键结构。模拟心脏电生理导管消融治疗显示了联合方法的潜在益处。实时自适应导航在精确瞄准的同时减少了辐射暴露和问题。这项研究建立了一种新的医疗导航模式,可以提高精度、患者安全和辐射暴露。尽管在患者特定数据集成和实时算法开发方面存在局限性,但这种集成方法可以彻底改变医学学科的微创手术。这种新的导航方法需要进一步的研究、验证和临床试验,以确认其可行性和有效性,并改善医疗患者护理
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引用次数: 0
AI-Driven approach for enhancing nuclear reactor safety predictive anomaly detection and risk assessment 基于人工智能的核反应堆安全预测异常检测与风险评估方法
Pub Date : 2023-06-30 DOI: 10.35335/eh0bph05
Qureshi Sethu Russell, Nichols Peng Linzi
Nuclear power plays a vital role in meeting global energy demands, but ensuring the safety of nuclear reactors remains a paramount challenge. In recent years, the emergence of artificial intelligence (AI) technologies has opened new avenues to significantly enhance nuclear reactor safety through predictive anomaly detection and risk assessment. This research proposes an innovative AI-driven approach that integrates machine learning techniques and data analytics to monitor, detect, and assess potential anomalies in nuclear reactors. The research begins with a comprehensive literature review on nuclear reactor safety and the application of AI in various industrial domains, emphasizing predictive maintenance and anomaly detection. It highlights the need for an AI-driven approach to enhance nuclear reactor safety proactively. In conclusion, this research establishes the transformative potential of AI in enhancing nuclear reactor safety. The proposed AI-driven approach empowers operators with powerful tools to ensure the safe and efficient operation of nuclear power plants. As AI technologies continue to advance, the research opens doors for further exploration and development, paving the way for a more sustainable and secure future in nuclear energy production.
核电在满足全球能源需求方面发挥着至关重要的作用,但确保核反应堆的安全仍然是一项重大挑战。近年来,人工智能(AI)技术的出现为通过预测性异常检测和风险评估显着提高核反应堆安全性开辟了新的途径。本研究提出了一种创新的人工智能驱动方法,该方法集成了机器学习技术和数据分析,以监测、检测和评估核反应堆中的潜在异常。研究首先对核反应堆安全和人工智能在各个工业领域的应用进行了全面的文献综述,重点介绍了预测性维护和异常检测。它强调需要人工智能驱动的方法来主动提高核反应堆安全。总之,本研究确立了人工智能在提高核反应堆安全方面的变革潜力。拟议的人工智能驱动方法赋予运营商强大的工具,以确保核电站的安全高效运行。随着人工智能技术的不断进步,这项研究为进一步的探索和开发打开了大门,为核能生产的更可持续和更安全的未来铺平了道路。
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引用次数: 0
Innovative approaches to nuclear energy density optimization for enhanced power generation and waste minimization 核能密度优化的创新方法,以增强发电和减少废物
Pub Date : 2023-06-30 DOI: 10.35335/5jd0hm75
Muellner Gufler Kromp, Frechette Pascual Zambetakis, Wood Wood
Nuclear energy has emerged as a viable low-carbon option for electricity generation, but traditional reactor designs face challenges regarding energy density and nuclear waste management. This research explores innovative approaches to optimize nuclear energy density while minimizing long-term environmental impact through reduced waste production. The study compares a traditional Pressurized Water Reactor (PWR) with an advanced Molten Salt Reactor (MSR) as the innovative technology. The objectives are to maximize energy density and minimize nuclear waste. A multi-objective optimization model is formulated, incorporating safety, operational, and environmental constraints. Numerical results demonstrate that the MSR achieves a higher energy density (30 MW/kg) than the PWR (20 MW/kg) and produces less waste (0.2 kg/MW vs. 0.5 kg/MW). The research highlights the potential benefits of innovative nuclear technologies and emphasizes the importance of safety evaluations, regulatory considerations, and economic viability for practical implementation. Collaborative efforts and supportive policies are crucial to realizing a sustainable and low-carbon energy future through advanced nuclear solutions
核能已经成为一种可行的低碳发电选择,但是传统的反应堆设计面临着能量密度和核废料管理方面的挑战。本研究探索创新方法,以优化核能密度,同时通过减少废物产生,最大限度地减少对环境的长期影响。将传统的压水堆(PWR)与先进的熔盐堆(MSR)作为创新技术进行了比较。目标是最大限度地提高能量密度,并尽量减少核废料。建立了一个考虑安全、运行和环境约束的多目标优化模型。数值结果表明,MSR的能量密度(30 MW/kg)高于压水堆(20 MW/kg),产生的废物更少(0.2 kg/MW vs. 0.5 kg/MW)。该研究强调了创新核技术的潜在好处,并强调了安全评估、监管考虑和实际实施的经济可行性的重要性。合作努力和支持性政策对于通过先进的核解决方案实现可持续的低碳能源未来至关重要
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引用次数: 0
Advancements in radiochemistry and nuclear methods of analysis for safer and sustainable applications 放射化学和核分析方法在安全和可持续应用中的进展
Pub Date : 2023-06-30 DOI: 10.35335/v4t2dh66
Sosuke Han Sanada, Richard Nichida Shrestha
This research investigates radiochemistry and nuclear analysis technologies to make applications safer and more sustainable. A mathematical optimization approach optimizes radiopharmaceutical synthesis parameters for positron emission tomography (PET) imaging to maximize yield and minimize radioactive waste. Optimizing critical parameters improves the efficiency, safety, and sustainability of radiochemistry and nuclear technologies in medical imaging, nuclear energy, and environmental monitoring. The numerical example shows that optimization achieves the study goal. Optimization strategies improve medical imaging by increasing radiopharmaceutical yield and decreasing radioactive waste volume. Real-world implementation requires cost-effectiveness, safety restrictions, and numerous synthesis factors. Researchers, policymakers, and industry professionals must collaborate to enhance human and environmental welfare, according to the report. In conclusion, this research advances radiochemistry and nuclear procedures for safer and more sustainable applications, mitigating hazards and environmental effect and ensuring a safer and more sustainable future for nuclear technology.
本研究探讨放射化学和核分析技术,使应用更安全,更可持续。一种数学优化方法优化了正电子发射断层扫描(PET)成像的放射性药物合成参数,以最大限度地提高产量并减少放射性废物。优化关键参数可提高放射化学和核技术在医学成像、核能和环境监测方面的效率、安全性和可持续性。数值算例表明,优化达到了研究目标。优化策略通过增加放射性药物产量和减少放射性废物体积来改善医学成像。现实世界的实现需要成本效益、安全限制和许多综合因素。报告指出,研究人员、政策制定者和行业专业人士必须合作,以提高人类和环境福利。总之,这项研究促进了放射化学和核程序的更安全和更可持续的应用,减轻了危害和环境影响,并确保核技术的未来更安全和更可持续。
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引用次数: 0
Psychosocial determinants, adherence to health policies, and support searching in adults in Córdoba city, Argentina, under pandemic context 大流行病背景下阿根廷科尔多瓦市成年人的社会心理决定因素、对卫生政策的遵守情况以及寻求支持的情况
Pub Date : 2023-04-10 DOI: 10.53680/vertex.v34i159.360
Facundo Ruffinatto, Verónica Grasso, Eliza Erro, Magdalena Cáseres

Introduction: Pandemics throughout human history have caused global crises. Given their multifactorial impact, they generate changes in the functioning of the health pole, in the adaptation of the health system, the economy of nations, in political decision-making, and lifestyles. At the individual level, changes in behavior, emotions, thoughts, and quality of life in its many aspects (physical, psychological, social, and environmental) are glimpsed.

Materials and method: With a quantitative approach of cross-sectional ex post facto design, and exploratory scope, the psychosocial and sociodemographic aspects related to adherence to health policies and the search for support were investigated in the adult population of the city of Córdoba (20 to 60 years). 704 people were surveyed, to whom the perceived stress questionnaire (pss-10), a sociodemographic questionnaire, and a questionnaire carried out with an ad hoc modality were applied.

Results and conclusions: Age, sex, schooling, health history, psychiatric/psychological history, and having relatives/partners belonging to a risk group; they presented an association with respect to adherence to health policy regulations; fear of getting infected; help/support seeking; and perceived stress. This research aims to be a starting point to promote local studies that investigate adherence to health policy regulations necessary to cope with the spread of a disease worldwide with the fewest possible adverse reactions.

导言:人类历史上的大流行病造成了全球性危机。大流行病的影响是多方面的,它改变了卫生部门的运作、卫生系统的适应、国家经济、政治决策和生活方式。在个人层面上,行为、情感、思想和生活质量等多方面(生理、心理、社会和环境)都会发生变化:采用事后横断面定量设计和探索性方法,对科尔多瓦市的成年人口(20 至 60 岁)进行了与遵守卫生政策和寻求支持有关的社会心理和社会人口方面的调查。对 704 人进行了调查,采用了压力感知问卷 (pss-10)、社会人口调查问卷和临时调查问卷:结果和结论:年龄、性别、受教育程度、健康史、精神病史/心理史、有属于风险群体的亲属/伴侣;这些因素与遵守卫生政策法规、害怕感染、寻求帮助/支持和感知压力有关。这项研究旨在作为一个起点,促进地方研究,调查遵守必要的卫生政策法规的情况,以应对疾病在全球的传播,并尽可能减少不良反应。
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引用次数: 0
Meanings and practices about work of women discharged from a psychiatric hospital of Buenos Aires province, Argentina 阿根廷布宜诺斯艾利斯省精神病院出院妇女对工作的理解和实践
Pub Date : 2023-04-10 DOI: 10.53680/vertex.v34i159.365
María Isabel Harfiel, Sara Ardila-Gómez

Introduction: Work is central to the social inclusion of people who have had long-term psychiatric hospitalizations. In the context of the mental health care reform in Argentina, it is important to produce local knowledge about workinclusion of people discharged from psychiatric hospitals. The objective of this study was to describe the meanings and practices of women who had long-term psychiatric hospitalizations at the José A. Estéves Hospital in the Province of Buenos Aires, Argentina, regarding their inclusion in the labor market, once they return to live in the community.

Methods and materials: Descriptive mixed-methods study. The case of the Assisted Discharge and Rehabilitation Program of José A. Estéves Hospital, which accompanied 69 women in the year 2018, was analyzed. For quantitative analysis the data of the 69 women was analyzed, and for qualitative analysis a sample of nine women were interviewed.

Results: 74% of women did some work after their discharge, although at the moment of the study only 33% were working. The jobs they carried out corresponded to elementary and low-competence occupational levels, mostly in a supported work program. After the psychiatric hospitalization, jobs obtained were less qualified, more informal and less exposed to the public than those held before the hospitalization.

Discussion and conclusionss: Prolonged psychiatric hospitalization is a significant break in people’s work trajectories. Despite the value of work experiences after having a psychiatric hospitalization, those experiences mainly correspond to the informal sector of the economy.

简介工作是精神病长期住院患者融入社会的核心。在阿根廷精神卫生保健改革的背景下,了解当地精神病院出院人员的工作融入情况非常重要。本研究旨在描述阿根廷布宜诺斯艾利斯省何塞-埃斯特韦斯医院(José A. Estéves)的长期精神病住院妇女在重返社区生活后,在融入劳动力市场方面的意义和做法:描述性混合方法研究。分析了何塞-A-埃斯特韦斯医院辅助出院和康复计划的案例,该计划在 2018 年陪伴了 69 名妇女。为了进行定量分析,对69名妇女的数据进行了分析,为了进行定性分析,对9名妇女进行了抽样访谈:74%的妇女在出院后从事过一些工作,尽管在研究时只有33%的妇女在工作。她们从事的工作属于初级和低能力职业,大多是在辅助性工作计划中。与住院前相比,精神病患者住院后所从事的工作更低级、更不正式,也更少接触公众:讨论和结论:长期的精神病住院治疗是人们工作轨迹中的一个重要断点。尽管精神病住院后的工作经历很有价值,但这些经历主要是在非正规经济部门。
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引用次数: 0
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Vertex (Buenos Aires, Argentina)
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