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Archives d'ophtalmologie et revue generale d'ophtalmologie最新文献

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Immunological comparison of normal, regenerating, and cultured corneal cells. 正常、再生和培养角膜细胞的免疫学比较。
W Manski

Two types of corneal cell membrane receptors are described, one occurs on the surface of only regenerating or cultured cells, that is, actively metabolizing and/or proliferating ones. The other type of corneal membrane receptors occurs on the cell surface independent of the metabolic state, e.g. on excised resting cells. In contrast to the restricted ontogenic specificity of the metabolically dependent corneal cell membrane antigens, the metabolically independent cell surface antigens were found to be universally distributed across ontogenic or species barriers. Such metabolically independent corneal cell surface antigens include Forssman or blood group antigens. The immuno-cytotoxic reaction of corneal cells involving the metabolically independent cell surface antigens was enhanced by complement, whereas a similar immunocytotoxic reaction involving the metabolically dependent antigens was not.

描述了两种类型的角膜细胞膜受体,一种仅发生在再生或培养细胞的表面,即积极代谢和/或增殖的细胞。另一种类型的角膜膜受体发生在细胞表面,与代谢状态无关,例如在切除的静息细胞上。与代谢依赖的角膜细胞膜抗原有限的个体特异性相反,代谢独立的细胞表面抗原被发现普遍分布在个体或物种屏障上。这种代谢独立的角膜细胞表面抗原包括福斯曼抗原或血型抗原。补体增强了角膜细胞对代谢不依赖的细胞表面抗原的免疫细胞毒性反应,而对代谢依赖的抗原的免疫细胞毒性反应则没有增强。
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引用次数: 0
The corneal host-graft function. Physiopathology of the scar. 角膜宿主移植功能。疤痕的生理病理。
F M Polack

The scar of penetrating homografts was studied in experimental grafts in rabbits and monkeys. The purpose of the study was to analyze the healing process in those grafts and correlate these findings to clinical situations of abnormal graft healing. Light, transmission and scanning electron microscopy were done for morphological studies. Radioautography with tritiated thymidine and S-35 sulfate was done to study cell repopulation and ground substance development in the scar. More than 50 p. 100 of cells present in the scar came from the host and lay down circular collagen fibers in the stroma and new Descemet's material at the endothelial level. Very tight (continuous) 10-0 nylon sutures produce necrosis of the edge of the wound and delay healing. From the morphological point of view it appears that very thin scars have less tensile strength than wider scars. These usually show circular and crisscrossing collagen fibers. Radial scars induced by silk sutures or through and through placed monofilament nylon add tensile strength to the wound.

在兔和猴的实验移植中研究了穿透性同种移植物的疤痕。本研究的目的是分析这些移植物的愈合过程,并将这些发现与移植物异常愈合的临床情况联系起来。光镜、透射电镜和扫描电镜观察形态学变化。用氚化胸腺嘧啶和硫酸S-35进行放射自显影,研究瘢痕内细胞的再生和基质物质的发育。瘢痕中超过50%的细胞来自宿主,在基质中形成圆形胶原纤维,在内皮层形成新的Descemet物质。非常紧的(连续的)10-0尼龙缝线会导致伤口边缘坏死并延迟愈合。从形态学的角度来看,很薄的疤痕比更宽的疤痕具有更低的抗拉强度。这些通常显示圆形和交叉的胶原纤维。由丝线缝合或通过放置单丝尼龙引起的放射状疤痕增加了伤口的抗拉强度。
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引用次数: 0
Medium-term preservation of the cornea. 中期保存角膜。
M Itoi
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引用次数: 0
Biosynthesis of connective tissue components in corneal wound healing. 结缔组织成分在角膜创面愈合中的生物合成。
P M Leuenberger, M C Gnädinger
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引用次数: 0
[Inturgescent cornea]. [扩张性角膜]。
P Payrau
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引用次数: 0
[Histological aspects of preserved cornea. Criteria of survival, behavior of the graft]. 保存角膜的组织学方面。存活标准,移植物的行为]。
A Gajdos, J P Faure
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引用次数: 0
In vivo determination of fluorescein permeability of the corneal endothelium. 角膜内皮荧光素通透性的体内测定。
S Mishima
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引用次数: 0
Corneal cryo-preservation and its clinical application. 角膜冷冻保存及其临床应用。
H E Kaufman

Shortage of fresh corneal tissue for keratoplasty and expensive equipment needed for cryo-preservation has confined the field of corneal transplantation. The development of a simple medium for storage of corneal tissue which is inexpensive, which requires no technical assistance, and which provides the surgeon with excellent tissue would be very helpful. Forty-five of 55 human corneas stored for up to seven days in a simple tissue culture medium remained clear and thin after keratoplasty. Corneal deturgescence rates of tissue stored in this medium compared favorably with those rates for fresh and cryopreserved tissue.

角膜移植术所需新鲜角膜组织的缺乏和冷冻保存所需昂贵的设备限制了角膜移植领域的发展。开发一种简单的角膜组织储存介质,这种介质价格低廉,不需要任何技术帮助,而且可以为外科医生提供优质的组织,这将非常有帮助。在简单组织培养基中保存7天的55个人角膜中,有45个角膜在角膜移植后仍保持透明和薄。在这种介质中储存的组织的角膜消肿率优于新鲜和冷冻保存的组织。
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引用次数: 0
[Homage to Doctor Barbara Robert]. [向芭芭拉·罗伯特博士致敬]。
A Delaunay
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引用次数: 0
[Physiopathology of the keratocytes in lattice and spotted dystrophies of the cornea]. [角膜晶格状和斑点状营养不良的角化细胞的生理病理学]。
J François, V Victoria-Troncoso
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引用次数: 0
期刊
Archives d'ophtalmologie et revue generale d'ophtalmologie
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