Arztliche Jugendkunde最新文献

Taking account of the gestational age (28th to 42nd completed week of pregnancy) the sex-related ratio of birth weight to length (g/cm) for newborn infants is reported. This shows that observation of the correlation between birth weight and length with reference to gestational age makes a more accurate classification of newborn infants possible, rather than using a two dimensional classification (birth weight week of gestation).

Using the data of the 1985 GDR somatogram standards (birthweight percentiles calculated from 51,570 liveborn singletons) the impact of parental weight and length on the birthweight were calculated. Peristatic factors in combination with the genetic 'anlage' act first of all via maternal weight. Body height and/or length of mother and father are more representative for the genetic constitution. Their impact on neonatal weight seems to be less significant, however statistically calculable. The paternal 'anlage' is relatively modified by the intrauterine environment (maternal constitution).

Variations in the body weight of 550 healthy sporting girls aged 9 to 12 years (urban population) were examined with reference to the stage of their biological development. A classification in percentages (from 80% to 150%) for the evaluation of body weight in medical practice is depicted in tabular form and provides a ready and reliable means for examining body weight as a basis which may have therapeutic consequences.

In a series of 153 women with intake of drugs during early pregnancy the pregnancy was terminated in 22% of all cases. There were the following results of the 119 non-terminated pregnancies: delivery of a normal, healthy baby: 84%; abortion: 5%; still birth and premature birth, respectively: 3,5%. An abnormal phenotype was seen in 7% of the newborns, but only 3 cases with major malformation (cleft lip, club-foot, cataract) could be noted. Compared with normal pregnancies the results do not confirm an enhanced risk for malformations by intake of drugs during early pregnancy. Unfounded anxiety of physicians as well as of pregnant women with indicated pharmacotherapy should be reduced by better information and education.

Data obtained from 10,108 newborns of parents of gypsy native language delivered during 1973-1983 were compared to national population's data of 1978. When comparing the data of gypsy group which is living under very disadvantageous social, cultural and health conditions to the appropriate national data the following differences have been found. The physical development of gypsy infants included in this study is much more worse than that of the national average. For the poorer physical development of gypsy children the disadvantageous social and hygienic conditions together with low educational attainment is responsible rather than the different genetic background. This conclusion is proved by findings of the study that the trend of national data according to the educational attainment is very similar to that of the appropriate data of gypsy group.

Methods, tests and criterions for selection of children and adolescents talented for sport are described. A review is given on the author's investigations on the genetic conditionality of the prerequisites for performances in sport based on twin studies and on the developmental stability of the selection criterions tested.

Studies of children participating in elite sport training programmes revealed growth disorders. Longitudinal analyses of female gymnasts (whose bone age was distinctly below chronological age) over a period of two years do not suggest a general tendency to growth inhibition. However, the marked variation in the longitudinal data may indicate retardation in individual cases. An evaluation of the growth parameters is of practical importance for the medical care of children participating in intensive training programmes.

The main employment of stomatology with curative matters and material problems caused a neglect of genetic aspects in the aetiology of dental caries and marginal periodontitis. A critical review of literature is the base of proposals for consideration of genetic aspects in the fields of stomatologic epidemiology, dental health care programs and dental health care education.

The validity of Zazzo's questionnaire method for zygosity determination has been tested within the framework of a study on twins. 11 (20.7%) of 53 monozygotic twin pairs were classified incorrectly. For the diagnosis of zygosity in adolescent twins, a questionnaire method has been designed and implemented in the G.D.R. With the help of this new method a relatively reliable zygosity determination is possible. A correct matching for 97% was obtained.