Pahlavi medical journal最新文献

Respiratory air flow during electrical stimulation of the medullary respiratory neurons was measured in 25 sodium pentobarbital-anesthetized cats. The effect of variation of stimulus parameters on the air flow was studied too. The medullary respiratory neurons were localized by exploring the medulla with microelectrodes. The inspiratory neurons were found hetween 2 and 4 mm lateral to the midline, and from the level of the obex to 4 mm rostrally in the ventral reticular formation. The expiratory cells were between 2 and 3 mm lateral to the midline, extending from the level of the obex to 3 mm caudally, slightly less ventral than the inspiratory neurons. The maximal inspiratory and expiratory flow rates were 56 and 44 liters per minute respectively when the respiratory neurons were stimulated with a stimulus of 4 volts and 200 Hz/sec., while duration of the stimulating pulse was 0.5 millisecond. In general, the increase in air flow was proportional to the magnitude of the stimulus strength, stimulus frequency and duration of the stimulating pulse.

The lipolytic responses to dihydroergotamine (5 mug/mi) of isolated rat adipocytes andto epinephrine (50 ng/m1 and 1 mug/m1) of both rat and dog adipocytes were measured over a period of two hours. Glycerol release was calculated as a function of either glycerol ester content or of cell number per incubation vial. The conventional calculation based on glyceride content gave the following results: a) epididymal fat cells from rats weighing less than 160 gm were more sensitive to dihydroergotamine and epinephrine than were fat cells from heavier animals weighing close to 200 gm; b) dog adipocytes from abdominal subcutaneous tissue were less sensitive to eipnephrine than were rat adipocytes. No such differences were noted when the same data were calculated on the basis of cell numbers per incubation vial: the lipolytic response was uniform with rat adipocytes obtained either from the lighter or the heavier weight groups, and so was the response of dog and rat cells. These results indicate that in the type of studies where receptor-dependent hormone and drug effects are measured, the number of cells per incubation vial is an important parameter to be considered in evaluating a lipolytic response.

An operational model of the processes of decision making in the development of curriculum was porposed. Attempts were made to present a conceptual framework from which the model was elaborated. In addition, examples of field experience related to the application of educational planning theory into practive were presented.

Twelve non-thrombocytopenic patients ( 3 males and 9 females) with systemic lupus erythematosus (SLE) were investigated with respect to platelet size, percentage of megathrombocytes, platelet survival and platelet production. The values for platelet size and percentage of megathrombocytes did not differ from those of a control group. In the SLE group the mean platelet MLS was identical to the control mean, and all patients with SLE had values for platelet MLS within the range of the control subjects. All SLE patients but one had values for platelet turnover within the control range. For unclear reason one single SLE patient had a moderately elevated platelet turnover value. The results of the present investigation do not support the theory that a state of compensated thrombocytolysis is present in SLE.

A new type of external fixator bas been designed for absolute fixation and prevention of lateral migration of fragments of bone. The apparatus has been used for leg lengthening. The apparatus and the technique are described and results of the first 24 cases are presented. Complications were minimal. The technique proved to be simple to apply, and painless to the patient with his ambulation from the start. And less expense are involved because of a very short period of hospitalization.

A 4 1/4-year-old male child with the Hutchinson-Gilford progeria syndrome is described. This is the first case to be reported from Iran.