Pahlavi medical journal最新文献

Thirty-four patients with tuberculosis were skin tested with 5 tuberculin units (TU) of purified protein derivative of Mycobacterium tuberculosis (PPD). PPD supplied by Park Davis and Co., Detroit, Michigan, U.S.A. (PPD-PD) as well as PPD obtained from The Razi Institute, Hessarak, Teheran (PPD-RI) were both used for skin testing in each patient. The results indicate that 74-79% of patients with active tuberculosis have positive tuberculin reactions, that PPD-RI is a potent source of tuberculin for skin testing and that a substantial proportion of our tuberculous patients (21-26%) have negative tuberculin skin reactions.

From October 1973 to September 1974, throat cultures were taken from 578 patients who referred to the Children's Clinic with upper respiratory tract infection. One hundred fifty-one (26%) of the sick children yielded beta-hemolytic streptococci and 427 (74%) of the pharyngitis cases were considered as viral. The most susceptible ages for streptococcal and viral pharyngitis were 5-8 and 2-6 years respectively. The peak seasonal incidence for streptococcal sore throat was from late autumn to early spring. There was a positive correlation between the incidence of upper respiratory infection and streptococcal isolation. From 100 strains of beta-hemolytic streptococci isolated and tested, 86 were group "A", 4 group "C", 2 group "G" and 8 non-groupable. From 86 group "A" strains. 71 (82%) were typable by agglutination ("T"-typing), but only 49 (57%) by precipitation ("M"-typing). The most prevalent "M" types were types 1 and 12. There was 95% correlation between serological and bacitracin disk method for grouping of hemolytic streptococci. All strains isolated were sensitive to penicillin, erythromycin and chloramphenicol, but 11 strains were resistant to tetracyclin.

The fifth case of colonic malakoplakia involving children under the age of 13 years is reported. Rectoscopic findings were strongly suggestive of a colonic carcinoma. A detailed review of literature on malakoplakia is also made.

A rise in ASO titre can be demonstrated in 75-80% of patients following untreated streptococcal upper respiratory infection. The difficulty, however, is that there is no such thing as normal ASO titre. The levels encountered in a given population depend upon age, geographical location, season, etc. It was, therefore, on this basis that sera were taken from 3129 healthy individuals during winter and summer in Tehran for the determination of ASO titres. Sixty-three individuals were treated both during summer and winter. During summer only 4 (6%) had titres above 250 T.U. and 59 (94%) below 250 T.U. The same individuals, when tested during the winter, showed that 7 (11%) had ASO titres above 250 T.U. and 56 (89%) below 250 T.U. This seasonal difference is statistically significant. In another study 320 individuals were tested during summer and another 394 individuals during winter. Among the summer group 31 (10%) were above 250 T.U. and 289 (90%) were below 250 T.U. In the winter group 55 (14%) were above 250 T.U. and 339 (86%) were below 250 T.U. This difference is again statistically significant. Further, 35 samples of pooled sera representing 2289 individuals were treated during the winter. Here 563 (24%) were above and 1723 (76%) were below 250 T.U. The possible sources of error in this group, in comparison with the other, are discussed.

Daily pollen counts were made in Tehran by placing a Durham sampler on the roof of the College of Pharmacy building at the University of Tehran. Three pollen seasons were identified in Tehran. Tree season extended from the first week of February through the middle of October. Important pollens of tree season were Willow, Cedar, Sycamore, Pine, Alder, Walnuts, Elm, Cottonwood, Oak and/or Maple, Birch, and Beech. The grass season started from the first week of May and extended into the second week of November. The weed season began at the middle of May and lasted until the last week of December. Important weed pollens belonged to various members of the Order Chenopodials, particularly Burning Bush, and Russian Thistle. Sagebrush and English Plantain were also abundant during the weed season.