Pub Date : 2023-01-01DOI: 10.47829/ajsccr.2023.61002
Serrano-Méndez P, Perez-Chrzanowska H
{"title":"Retroperitoneal Mesothelial Cyst: An Incidental Finding","authors":"Serrano-Méndez P, Perez-Chrzanowska H","doi":"10.47829/ajsccr.2023.61002","DOIUrl":"https://doi.org/10.47829/ajsccr.2023.61002","url":null,"abstract":"","PeriodicalId":7649,"journal":{"name":"American Journal of Surgery and Clinical Case Reports","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82408575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.47829/ajsccr.2023.6602
C. J, Florenly, L. C
{"title":"Thoughts and Suggestions for Lower Alveolar Nerve Injury Caused by Tooth Extraction on the Lower Left 8th Tooth: A Case Report","authors":"C. J, Florenly, L. C","doi":"10.47829/ajsccr.2023.6602","DOIUrl":"https://doi.org/10.47829/ajsccr.2023.6602","url":null,"abstract":"","PeriodicalId":7649,"journal":{"name":"American Journal of Surgery and Clinical Case Reports","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80252613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.47829/ajsccr.2023.61218
Young Ar, Amin A, Ram B, Sham S, Monika SA, Paterson J
The World Health Organization classified neuroendocrine neoplasms of the digestive system into well-differentiated neuroendocrine tumor (NET) and poorly-differentiated neuroendocrine carcinoma (NEC) based on their unique morphological, clinical, epidemiological, histological, and prognostic differences. We pres-ent a case of an 80-year old female found to have a 31x22x21 mm mass in the perihilar common bile duct on CT scan. A tan-yellow mass within the common bile duct wall, extending into the surrounding fibroconnective tissue was noted on gross examination. Histologic examination revealed a well-circumscribed tumor with a biphasic appearance consisting of predominantly well-differentiated NET (approximately 80%) arranged in a trabecular architecture with round nuclei, finely granular chromatin, moderate cytoplasm, rare mitosis (6/2mm 2 ), and minor poorly differentiated NEC (approximately 20%) with markedly pleomorphic cells, necrosis, and abundant mitosis (40/2mm 2 ). Tumor cells in both morphologies showed immunoreactivity for AE1/AE3, CD56, synaptophysin and chromogranin. The Ki-67 proliferation index in the well-differentiated component was low (approximately 3-20%) and unequivocally high in the poorly-differentiated component (focally >50%). In the well-differentiated component, p53 staining was patchy and weak (wild-type), whereas it was negative (null-type) in the poorly-differentiated component. RB1 immunostaining showed weak staining in the well-differentiated component and diffusely strong staining in the poorly-differentiated component. The final diagnosis of mixed well-differentiated NET and poorly-differentiated NEC is made, which does not fit neatly into a specific category in the current classification of neuroendocrine neoplasms of the digestive system. Reporting more cases like this will be helpful for the revision of the current classification system.
{"title":"Mixed Poorly-Differentiated Neuroendocrine Carcinoma and Well-Differentiated Neuroendocrine Tumor in the Extrahepatic Common Bile Duct: A Unique Rare Case","authors":"Young Ar, Amin A, Ram B, Sham S, Monika SA, Paterson J","doi":"10.47829/ajsccr.2023.61218","DOIUrl":"https://doi.org/10.47829/ajsccr.2023.61218","url":null,"abstract":"The World Health Organization classified neuroendocrine neoplasms of the digestive system into well-differentiated neuroendocrine tumor (NET) and poorly-differentiated neuroendocrine carcinoma (NEC) based on their unique morphological, clinical, epidemiological, histological, and prognostic differences. We pres-ent a case of an 80-year old female found to have a 31x22x21 mm mass in the perihilar common bile duct on CT scan. A tan-yellow mass within the common bile duct wall, extending into the surrounding fibroconnective tissue was noted on gross examination. Histologic examination revealed a well-circumscribed tumor with a biphasic appearance consisting of predominantly well-differentiated NET (approximately 80%) arranged in a trabecular architecture with round nuclei, finely granular chromatin, moderate cytoplasm, rare mitosis (6/2mm 2 ), and minor poorly differentiated NEC (approximately 20%) with markedly pleomorphic cells, necrosis, and abundant mitosis (40/2mm 2 ). Tumor cells in both morphologies showed immunoreactivity for AE1/AE3, CD56, synaptophysin and chromogranin. The Ki-67 proliferation index in the well-differentiated component was low (approximately 3-20%) and unequivocally high in the poorly-differentiated component (focally >50%). In the well-differentiated component, p53 staining was patchy and weak (wild-type), whereas it was negative (null-type) in the poorly-differentiated component. RB1 immunostaining showed weak staining in the well-differentiated component and diffusely strong staining in the poorly-differentiated component. The final diagnosis of mixed well-differentiated NET and poorly-differentiated NEC is made, which does not fit neatly into a specific category in the current classification of neuroendocrine neoplasms of the digestive system. Reporting more cases like this will be helpful for the revision of the current classification system.","PeriodicalId":7649,"journal":{"name":"American Journal of Surgery and Clinical Case Reports","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84277219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.47829/ajsccr.2022.6462
None Hasan F
{"title":"Logistic Regression Model of Factors Influencing Maternal Health Care Service Utilization in Bangladesh: A Nationwide Cross-Sectional Study","authors":"None Hasan F","doi":"10.47829/ajsccr.2022.6462","DOIUrl":"https://doi.org/10.47829/ajsccr.2022.6462","url":null,"abstract":"","PeriodicalId":7649,"journal":{"name":"American Journal of Surgery and Clinical Case Reports","volume":"2013 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135495817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.47829/ajsccr.2023.6919
Groudeva V, Chilingirova N, Nedevska M, Iovev S
Adult patients with transposition of great vessels are often candidates for cardiac resynchronization therapy (CRT). Cardiac vein anatomy is of crucial importance in planning optimal CRT therapy. Cardiac veins are very variable. In congenitally corrected transposition of great vessels coronary arteries have an unusual course but coronary veins although much less studied have much more varieties. In such cases cardiac computed tomography (CT) might offer important information prior to electrophysiological procedures. The objective of this study is to present a series of patients with transposition of the great arteries (TGA) both congenitally corrected TGA and D TGA in which imaging was used to help planning placement of leads for CRT. CT findings are thoroughly described as well as the consequent interventional procedure.
{"title":"Computed Tomography Cardiac Veins Evaluation in Congenital Transposition of Great Vessels Prior to Cardiac Resynchronization Therapy (Crt)","authors":"Groudeva V, Chilingirova N, Nedevska M, Iovev S","doi":"10.47829/ajsccr.2023.6919","DOIUrl":"https://doi.org/10.47829/ajsccr.2023.6919","url":null,"abstract":"Adult patients with transposition of great vessels are often candidates for cardiac resynchronization therapy (CRT). Cardiac vein anatomy is of crucial importance in planning optimal CRT therapy. Cardiac veins are very variable. In congenitally corrected transposition of great vessels coronary arteries have an unusual course but coronary veins although much less studied have much more varieties. In such cases cardiac computed tomography (CT) might offer important information prior to electrophysiological procedures. The objective of this study is to present a series of patients with transposition of the great arteries (TGA) both congenitally corrected TGA and D TGA in which imaging was used to help planning placement of leads for CRT. CT findings are thoroughly described as well as the consequent interventional procedure.","PeriodicalId":7649,"journal":{"name":"American Journal of Surgery and Clinical Case Reports","volume":"94 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83686428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.47829/ajsccr.2023.6601
S. J, L. C, H. L.
{"title":"Thoughts and Suggestions of Grassroots Doctors (Gastroenterologists and General Practitioners) of Lower Gastrointestinal Bleeding Caused by Long-Term Use of Non-Steroidal Anti-Inflammatory Drugs and a Case Report","authors":"S. J, L. C, H. L.","doi":"10.47829/ajsccr.2023.6601","DOIUrl":"https://doi.org/10.47829/ajsccr.2023.6601","url":null,"abstract":"","PeriodicalId":7649,"journal":{"name":"American Journal of Surgery and Clinical Case Reports","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75472618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.47829/ajsccr.2023.61001
S. Chatterjee, TK Chatterjee, Tapan Kumar Chatterjee
When discussing happiness, it’s worth noting that serotonin, a magical substance found in the body, is essential to achieving a state of well-being. Serotonin is a naturally occurring monoamine neurotransmitter that transmits signals between nerve cells throughout the body, contributing significantly to mood stabilization and supporting other bodily functions such as digestion, blood clotting, and sleep. When serotonin levels in the brain are low, it can cause changes in mood and disrupt sleep patterns, which can lead to depression. However, it’s important to note that although 95% of the serotonin in the body is produced in the gut, it cannot cross the “blood-brain barrier” and thus has no impact on emotional status. Increasing serotonin levels in the brain appears to enhance communication between brain cells, resulting in an uplifted mood and reduced depression symptoms. Prescription antidepressants like Selective Serotonin Reuptake Inhibitors (SSRIs) are frequently employed to treat clinical depression and other mood disorders by increasing serotonin levels in the brain via blocking the Serotonin reuptake process. The 5-HT system is also thought to be a connection between the circadian system, stress, and mood. 5-HT not only plays a part in generating non-photic phase shifts, but it also counteracts the effects of light in the SCN (Suprachiasmatic nucleus) . It has been found that food and exercise can increase serotonin levels in the brain. Thus SSRIs use can be minimized (Figure 1).
{"title":"The Quest of Happiness-Increase Happy Neurotransmitter Serotonin in the Brain","authors":"S. Chatterjee, TK Chatterjee, Tapan Kumar Chatterjee","doi":"10.47829/ajsccr.2023.61001","DOIUrl":"https://doi.org/10.47829/ajsccr.2023.61001","url":null,"abstract":"When discussing happiness, it’s worth noting that serotonin, a magical substance found in the body, is essential to achieving a state of well-being. Serotonin is a naturally occurring monoamine neurotransmitter that transmits signals between nerve cells throughout the body, contributing significantly to mood stabilization and supporting other bodily functions such as digestion, blood clotting, and sleep. When serotonin levels in the brain are low, it can cause changes in mood and disrupt sleep patterns, which can lead to depression. However, it’s important to note that although 95% of the serotonin in the body is produced in the gut, it cannot cross the “blood-brain barrier” and thus has no impact on emotional status. Increasing serotonin levels in the brain appears to enhance communication between brain cells, resulting in an uplifted mood and reduced depression symptoms. Prescription antidepressants like Selective Serotonin Reuptake Inhibitors (SSRIs) are frequently employed to treat clinical depression and other mood disorders by increasing serotonin levels in the brain via blocking the Serotonin reuptake process. The 5-HT system is also thought to be a connection between the circadian system, stress, and mood. 5-HT not only plays a part in generating non-photic phase shifts, but it also counteracts the effects of light in the SCN (Suprachiasmatic nucleus) . It has been found that food and exercise can increase serotonin levels in the brain. Thus SSRIs use can be minimized (Figure 1).","PeriodicalId":7649,"journal":{"name":"American Journal of Surgery and Clinical Case Reports","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87699417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.47829/ajsccr.2023.6501
F. Rah, N. A, Jamtani I, W. A., Saunar Ry
Introduction: Choledochal cyst is rare malformation of the biliary system, characterized by abnormal cystic dilation in the biliary duct. There is no clear explanation regarding the etiology of the disease. Choledochal cysts are more common in Asian population, mainly diagnosed in children, particularly in females. Due to the rare incidence of giant choledochal cyst, evidence regarding safe operative approach was still scarce. This study aims to present the management option of type 1 giant choledochal cyst. Case presentation: We present a 26-year-old female patient with a chief complaint of intermittent right upper quadrant abdominal pain, which radiated to the back. The pain worsened while the patient was pregnant. The patient was then diagnosed with a giant choledochal cyst and concomitant left- and right- hepatic duct dilation with multiple gallstones. Results: We utilize Lilly’s technique, which involves cauterizing the mucosa while leaving the serosa connected to the adhering tissues. This method is helpful in giant long standing cyst, where the mucosa could not be entirely removed because it adhered to another structure, such as the pancreatic parenchyma, inferior vena cava, or hepatic hilar arteries. Conclusion: A complicated gigantic Type 1 choledochal cyst case benefits from Lilly’s method.
{"title":"Adult Giant Choledochal Cyst Conundrum: A Case Report","authors":"F. Rah, N. A, Jamtani I, W. A., Saunar Ry","doi":"10.47829/ajsccr.2023.6501","DOIUrl":"https://doi.org/10.47829/ajsccr.2023.6501","url":null,"abstract":"Introduction: Choledochal cyst is rare malformation of the biliary system, characterized by abnormal cystic dilation in the biliary duct. There is no clear explanation regarding the etiology of the disease. Choledochal cysts are more common in Asian population, mainly diagnosed in children, particularly in females. Due to the rare incidence of giant choledochal cyst, evidence regarding safe operative approach was still scarce. This study aims to present the management option of type 1 giant choledochal cyst. Case presentation: We present a 26-year-old female patient with a chief complaint of intermittent right upper quadrant abdominal pain, which radiated to the back. The pain worsened while the patient was pregnant. The patient was then diagnosed with a giant choledochal cyst and concomitant left- and right- hepatic duct dilation with multiple gallstones. Results: We utilize Lilly’s technique, which involves cauterizing the mucosa while leaving the serosa connected to the adhering tissues. This method is helpful in giant long standing cyst, where the mucosa could not be entirely removed because it adhered to another structure, such as the pancreatic parenchyma, inferior vena cava, or hepatic hilar arteries. Conclusion: A complicated gigantic Type 1 choledochal cyst case benefits from Lilly’s method.","PeriodicalId":7649,"journal":{"name":"American Journal of Surgery and Clinical Case Reports","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84426131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-23DOI: 10.47496/sl.ajscr.2022.01.02
G. Lauri, M. Di Stasi, G. Marinone, P. Arcidiacono, S. Russo, R. Conigliaro, G. Aragona
Introduction: Acute pancreatitis is the most frequent complication in patients who undergo endoscopic retrograde cholangiopancreatography (ERCP), with an incidence rate of 3.5-9.7% [1]. 5-10% of these develop acute necrotizing pancreatitis, which may have a pancreatic or peripancreatic localization in 75-80% [2]. We describe a case report of post-ERCP acute necrotizing pancreatitis with walled-off necrosis (WON) treated with percutaneous endoscopic necrosectomy (PEN) [3]. Case Report: A 60-year-old man with obstructive jaundice and common bile duct stones at abdominal CT scan underwent ERCP to clear the biliary tract. In the following days, due to the onset of severe acute pancreatitis and sepsis, he repeated the abdominal CT scan where multiple necrotic collections were found around the pancreas with extension to the pelvic paracolic gutters. Following a step-up approach, targeted antibiotic therapy was started. After four weeks, it was not possible to perform Endoscopic Ultrasound-Guided drainage because of the distance from the stomach or the duodenum to the WON. Then percutaneous drainage was radiologically inserted into the collections through the left side of the abdomen of the patient to flush with hydrogen peroxide every day. Due to the persistent infection and necrosis in the collections, an esophageal fully covered self-expanding metal stent was temporarily inserted through the percutaneous fistula in order to increase the caliber of the fistula and to perform PEN. Discussion: The step-up approach suggests endoscopic or percutaneous drainage of infected WON as the first interventional method, depending on the location of the WON and the local expertise [1]. PEN is a safe and effective alternative to surgical treatment with a technical success rate of 47-93% and a complication rate of no more than 20% [4]. Conclusion: PEN is an advanced endoscopic technique that is showing promising results but still needs randomized controlled trials to establish safety and efficacy.
{"title":"Percutaneous Endoscopic Necrosectomy of Walled-Off Necrosis in Post-ERCP Pancreatitis","authors":"G. Lauri, M. Di Stasi, G. Marinone, P. Arcidiacono, S. Russo, R. Conigliaro, G. Aragona","doi":"10.47496/sl.ajscr.2022.01.02","DOIUrl":"https://doi.org/10.47496/sl.ajscr.2022.01.02","url":null,"abstract":"Introduction: Acute pancreatitis is the most frequent complication in patients who undergo endoscopic retrograde cholangiopancreatography (ERCP), with an incidence rate of 3.5-9.7% [1]. 5-10% of these develop acute necrotizing pancreatitis, which may have a pancreatic or peripancreatic localization in 75-80% [2]. We describe a case report of post-ERCP acute necrotizing pancreatitis with walled-off necrosis (WON) treated with percutaneous endoscopic necrosectomy (PEN) [3]. Case Report: A 60-year-old man with obstructive jaundice and common bile duct stones at abdominal CT scan underwent ERCP to clear the biliary tract. In the following days, due to the onset of severe acute pancreatitis and sepsis, he repeated the abdominal CT scan where multiple necrotic collections were found around the pancreas with extension to the pelvic paracolic gutters. Following a step-up approach, targeted antibiotic therapy was started. After four weeks, it was not possible to perform Endoscopic Ultrasound-Guided drainage because of the distance from the stomach or the duodenum to the WON. Then percutaneous drainage was radiologically inserted into the collections through the left side of the abdomen of the patient to flush with hydrogen peroxide every day. Due to the persistent infection and necrosis in the collections, an esophageal fully covered self-expanding metal stent was temporarily inserted through the percutaneous fistula in order to increase the caliber of the fistula and to perform PEN. Discussion: The step-up approach suggests endoscopic or percutaneous drainage of infected WON as the first interventional method, depending on the location of the WON and the local expertise [1]. PEN is a safe and effective alternative to surgical treatment with a technical success rate of 47-93% and a complication rate of no more than 20% [4]. Conclusion: PEN is an advanced endoscopic technique that is showing promising results but still needs randomized controlled trials to establish safety and efficacy.","PeriodicalId":7649,"journal":{"name":"American Journal of Surgery and Clinical Case Reports","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78503795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-07DOI: 10.33597/2766-8304-v3-id1031
J. G., V. O, Holly G, Brad B, Jennifer C, Leonie R
Introduction: Medical Affairs teams within Medical Device Companies receive Medical Information Requests (MIR) from Healthcare Professionals (HCP) seeking answers to medical, scientific, or technical information because they cannot be answered based on the individual product’s current prescribing information, indications, Instructions for Use (IFU), as cleared or approved by the appropriate competent regulatory authority (e.g., Food and Drug Administration (FDA), Notified Body in the European Union, or other regional governmental authority). In 2018, Johnson & Johnson MedTech launched a Cloud-based platform to harmonize Medical Affairs’ global management and processing of MIRs from HCPs, seeking scientific or medical information about our portfolio of products. The aim of this comparative retrospective analysis was to critically examine the 2020 MIR volumes in 2020 versus 2019 and assess the impact of COVID-19 on Medical Affairs support of patients and Health Care Providers (HCPs). Methods: The authors conducted a retrospective analysis of Johnson & Johnson MedTech MIR data, across quarters from January 2019 through the December 2020, to evaluate the potential impact of the COVID-19 pandemic on MIR intake volume and key metrics. Results: The Total Global (US, EMEA, and ASPAC) year over year analysis of Total Johnson & Johnson MedTech MIR volume totaled, 2018-656*, 2019-1155 and 2020-1153. When stratifying Global year over year analysis of Regional (US, EMEA, and ASPAC) MIR data: US MedTech MIR volume for quarterly periods, including initial COVID-19 pandemic, Q2 2020 resulted in a 48% decrease in MIR volume across US MedTech MIR submissions, compared to Q2 2019. Q3 2020 resulted in a 43% increase in MIR volume across US MedTech MIR submissions, compared to Q3 2019. EMEA MedTech MIR volume for the quarterly periods, including initial COVID-19 pandemic, Q2 2020 resulted in a 23% decrease in MIR volume across EMEA MedTech MIR submissions, compared to Q2 2019. Q3 2020 resulted in a 22% increase in MIR volume across EMEA MedTech MIR submissions, compared to Q3 2019. ASPAC MIR volume for the quarterly periods, including initial COVID-19 pandemic, Q2 2020 resulted in an 11% increase in MIR volume across ASPAC MedTech MIR submissions, compared to Q2 2019. Q3 2020 resulted in a 90% increase in MIR volume across ASPAC MedTech MIR submissions, compared to Q3 2019. Analysis of Quarterly MIR volume by Region (US, EMEA, and ASPAC) compared to Quarterly MIR volume from Prior Year (2019-2020): US Q1-18%, Q2 -48%, Q3+39%, and Q4+7%, EMEA Q1-29%, Q2-30%, Q3+25%, and Q4+15%, and ASPAC Q1-16%, Q2+11%, Q3+90%, and Q4+256%. Conclusion: Total MIR submissions and responses continued with only small variance from the previous year when compared to annual periods, including the impact from the COVID-19 pandemic (2019 vs. 2020). Across Johnson & Johnson MedTech, Healthcare professionals and the commercial sales teams increased their use of the MIR submission website during
作品简介:医疗器械公司的医疗事务团队从医疗保健专业人员(HCP)那里收到医疗信息请求(MIR)，寻求医疗、科学或技术信息的答案，因为这些问题无法根据个别产品当前的处方信息、适应症、使用说明(IFU)得到相应主管监管机构(例如，食品和药物管理局(FDA)、欧盟公告机构、或其他地区政府机构)。2018年，强生医疗科技推出了一个基于云的平台，以协调医疗事务对医疗服务提供者的MIRs的全球管理和处理，寻求有关我们产品组合的科学或医疗信息。本比较回顾性分析的目的是严格检查2020年与2019年的MIR数量，并评估COVID-19对患者和卫生保健提供者(HCPs)医疗事务支持的影响。方法:作者对强生MedTech公司2019年1月至2020年12月的MIR数据进行了回顾性分析，以评估2019冠状病毒病大流行对MIR摄入量和关键指标的潜在影响。结果:Total Johnson & Johnson MedTech全球(美国、欧洲、中东和亚太地区)MIR销量的年度分析总计为2018-656*、2019-1155 *和2020-1153 *。在对地区(美国、欧洲、中东和亚太地区)MIR数据进行全球年度分层分析时:美国MedTech季度MIR量，包括最初的COVID-19大流行，与2019年第二季度相比，2020年第二季度美国MedTech MIR提交的MIR量减少了48%。与2019年第三季度相比，2020年第三季度美国MedTech MIR提交量增加了43%。EMEA MedTech MIR的季度量，包括最初的COVID-19大流行，2020年第二季度导致EMEA MedTech MIR提交的MIR量与2019年第二季度相比减少了23%。与2019年第三季度相比，2020年第三季度EMEA MedTech MIR提交量增加了22%。亚太地区各季度的MIR量，包括最初的COVID-19大流行，与2019年第二季度相比，2020年第二季度MedTech提交的MIR量增加了11%。与2019年第三季度相比，2020年第三季度亚太地区MedTech MIR提交量增加了90%。按地区(美国、EMEA和亚太地区)的季度MIR量与上一年(2019-2020)的季度MIR量比较分析:美国一季度-18%，第二季度-48%，第三季度+39%和第四季度+7%，EMEA一季度-29%，第二季度-30%，第三季度+25%和第四季度+15%，亚太地区一季度-16%，第二季度+11%，第三季度+90%和第四季度+256%。结论:与年度期间相比，MIR提交和回复总量与前一年的差异很小，包括2019年与2020年的COVID-19大流行的影响。在强生医疗科技公司，医疗保健专业人员和商业销售团队在2019冠状病毒病大流行期间增加了对MIR提交网站的使用，而由于社交距离准则，面对面的互动被禁止或限制。尽管2019冠状病毒病大流行，全球客户通过使用我们的交互式MIR提交网站和MIRO数字平台，从MedTech医疗事务部获得了丰富的数据和信息。MIRO允许对全球MIRs进行持续、及时的处理，这些MIRs与世界各地的基本医院活动和选择性程序有关，同时在世界各地强制执行有限的面对面互动。
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