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Intraparenchymal Primary CNS Marginal Zone Lymphoma: A Rare Disease or Rather a Highly Misdiagnosed Condition? A Case Report and a Literature Review 肺实质内原发性中枢神经系统边缘带淋巴瘤:一种罕见的疾病还是一种高度误诊的疾病?1例报告及文献综述
Pub Date : 2022-01-01 DOI: 10.47829/ajsccr.2022.4302
Castro Tpd, Souza Pde, Lauand L, Luz Jvc, Piazera Fz
1. Abstract 1.1. Context: Marginal zone lymphoma, also known as mucosa associated lymphoid tissue (MALT) lymphoma, is a low-grade neoplasm generally with good prognosis and treatable with radiotherapy – rarely has its initial presentation in the CNS. When it does, a dural presentation is more common. However, it represents an even more infrequent condition when it appears as a primary intraparenchymal lesion and tends to be misdiagnosed: a potential problem because, almost always, a less invasive approach is adequate as treatment. 1.2. Goal: This article brings forward a rare case of intraparenchymal primary CNS marginal zone lymphoma (PCNS MZL), aiming to add information to the literature about this atypical case and its diagnostic and therapeutic approach. 1.3. Method: We made a case report and a literature review. 1.4. Results: This article describes a rare condition that was reported only in few other studies, as well as the process of diagnosis and treatment, which led to a partial remission of the lesion and to a reduction of clinical features. 1.5. Conclusion: Intraparenchymal PCNS MZL is a rare and, possibly, underdiagnosed condition and should be remembered when facing an intraparenchymal brain mass. Further studies are required to develop protocols that ensure a more precise diagnostic reasoning considering this condition. 2. Introduction Primary CNS lymphomas are rare. The vast majority of cases in immunocompetent patients comprise the high grade Diffuse large B-cell lymphomas (DLBCLs), that typically are intraparenchymal. Accounting for the minority of lymphoma cases with initial presentation in the CNS, we have low grade lymphomas, that typically do not involve cerebral tissue and have predominant dural location, resembling meningiomas. [1, 2] [5]. This article is about an extremely rare presentation of an intraparenchymal primary CNS lymphoma: Primary CNS Marginal Zone Lymphoma (PCNS MZL) with no dural presentation – an indolent, low-grade lymphoma. [1-3] [5] MZL is also known as Mucosa Associated Lymphoid Tissue (MALT) lymphoma [11]. We provide a case report and a literature review of intraparenchymal PCNS MZL with a search that included all combinations of the following terms in the baselines PUBMED, MEDLINE and LILACS: ((marginal zone lymphoma) OR (mucosa-associated lymphoid tissue lymphoma) OR (MALT-type lymphoma) OR (MALT lymphoma) OR (MALToma) OR (low grade B cell lymphoma)) AND ((CNS) OR (Central Nervous System)) AND ((primary) OR (initial presentation)) AND (case report). After the primary selection, we excluded articles that didn ́t fit the criteria “intraparenchymal marginal zone lymphoma with initial presentation in the CNS” by analyzing titles and abstracts – that resulted in just five case reports. 3. Case Report The patient is a 40-year-old woman HIV negative with a history of seizure and headache. At admission, she presented with right frontoparietal headache and focal seizure with motor activity in the left upper lim
1. 抽象的1.1。背景:边缘带淋巴瘤,也称为粘膜相关淋巴组织(MALT)淋巴瘤,是一种低级别肿瘤,通常预后良好,可通过放疗治疗-很少以中枢神经系统为首发症状。当它出现时,硬脑膜表现更为常见。然而,当它表现为原发性肺实质内病变时,它代表一种更罕见的情况,并且容易被误诊:这是一个潜在的问题,因为几乎总是,侵入性较小的方法足以作为治疗方法。1.2. 目的:本文报道一例罕见的肺实质内原发性中枢神经系统边缘带淋巴瘤(PCNS MZL),旨在对这一非典型病例及其诊断和治疗方法的文献资料进行补充。1.3. 方法:进行病例报告和文献复习。1.4. 结果:本文描述了一种罕见的疾病,只有少数其他研究报道,以及诊断和治疗的过程,导致病变部分缓解和临床特征的减少。1.5. 结论:脑实质内PCNS MZL是一种罕见且可能未被诊断的疾病,在面对脑实质内肿块时应谨记。考虑到这种情况,需要进一步的研究来制定方案,以确保更精确的诊断推理。2. 原发性中枢神经系统淋巴瘤是罕见的。在免疫功能正常的患者中,绝大多数病例包括高级别弥漫性大b细胞淋巴瘤(DLBCLs),通常发生在实质内。考虑到最初表现在中枢神经系统的少数淋巴瘤病例,我们有低级别淋巴瘤,通常不累及脑组织,主要位于硬脑膜,类似脑膜瘤。[1,2][5]。这篇文章是关于一个非常罕见的原发性中枢神经系统淋巴瘤的实质内表现:原发性中枢神经系统边缘带淋巴瘤(PCNS MZL)无硬脑膜表现-一种惰性,低级别淋巴瘤。[1-3] [5] MZL又称黏膜相关淋巴组织淋巴瘤(MALT)[11]。我们提供了一个病例报告和文献综述,检索了PUBMED, MEDLINE和LILACS基线中以下术语的所有组合:((边缘区淋巴瘤)或(粘膜相关淋巴组织淋巴瘤)或(MALT型淋巴瘤)或(MALT淋巴瘤)或(MALToma)或(低级别B细胞淋巴瘤))and((中枢神经系统)或(中枢神经系统))and((原发性)或(初次表现))and(病例报告)。在初步选择之后,我们通过分析标题和摘要排除了不符合“以中枢神经系统为首发表现的肺实质内边缘区淋巴瘤”标准的文章,结果只有5例病例报告。3.病例报告患者为40岁女性,HIV阴性,有癫痫和头痛病史。入院时,患者表现为右侧额顶头痛和局灶性癫痫发作,左上肢运动活动,意识未受损。体格检查除局灶性癫痫外未见异常。增强MRI显示右侧额顶病变具有以下特征:浸润性和扩张性皮质-皮质下形成,T2和FLAIR呈高信号强度(图1A和2-a)。增强MRI也显示高信号强度
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引用次数: 0
Review on Effective Treatments of Burning Mouth Syndrome 灼口综合征的有效治疗方法综述
Pub Date : 2022-01-01 DOI: 10.47829/ajsccr.2022.4301
Ghasemi S, Zokaee H, Mirzaei F, Daroudi G
Ghasemi S1*, Zokaee H2, Mirzaei F3 and Daroudi G4 1DDS, MSc of Oral Surgery, Clinical Assistant Professor of OMFS Department of Augusta University ,GA,USA, 2Assisstant Professor of Oral and Maxillofacial Medicine, Dental Research Center, Golestan University of Medical Sciences, Gorgan, Iran 3Dentistry Student, Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran 4Dentistry Student, Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran
Ghasemi S1*, Zokaee H2, Mirzaei F3和Daroudi G4 1DDS,口腔外科硕士,美国乔治亚州奥古斯塔大学OMFS系临床助理教授,2伊朗戈勒斯坦医科大学牙科研究中心口腔颌面医学助理教授,伊朗戈勒斯坦医科大学牙科学生,学生研究委员会,伊朗戈勒斯坦医科大学牙科学生,学生研究委员会,伊朗戈勒斯坦
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引用次数: 0
The Effect of COVID-19 Pandemic on the Number and Pattern of Major Thoracic Surgical Cases in Hayatabad Medical Complex, Peshawar 2019冠状病毒病大流行对白沙瓦哈亚塔巴德综合医院胸外科大病例数量和模式的影响
Pub Date : 2022-01-01 DOI: 10.47829/ajsccr.2022.4602
Tahir I, Alizai Q, Ahmad, M., Ullah F, Hussain M
1.1. Introduction: COVID-19 pandemic affected the activities of every department, but most significantly the health department. It is essential to understand and quantify any such effects on the healthcare for better future planning. 1.2. Objective: We used de-identified retrospective data to 1) quantify the prevalence of common surgeries in the thoracic surgery department, 2) investigate the impact of COVID 19 on the patients’ characteristics, and number and proportion of the thoracic surgeries in our department, and 3) search for the possible causes for any such effects. 1.3. Materials and Methods: We used a HIPPA complaint retrospective data of the patients who had surgery in the Thoracic Surgery division of Hayatabad Medical Complex, between December 2018 to July 2021 to work out the effects of the pandemic on the amount and kinds of surgeries in the thoracic department during the pandemic. 1.4. Results: Our data consisted of a total of 242 cases. During the pandemic, the total number of thoracic surgeries increased by 53%. The top five most common thoracic surgeries during the pandemic identified by prevalence were decortication (34.2%), hydatid cystectomy (10.8%), emergency thoracotomy (7%), esophagectomy (5.7%), and feeding jejunostomy (5.7%). During the pandemic, thoracic surgeries were generally more prevalent among males, and among relatively younger patients (age ≤10 years). We saw a significant drop in the proportion of surgeries for oncologic indications. However, no significant change was seen in the baseline characteristics, complications and mortality of the cases. 1.5. Conclusion: Although the pandemic had no significant effect on the baseline characteristics and the safety and efficacy of our procedures, the unplanned diversion of patients from other hospitals resulted in a sudden increased burden on our unit. We recommend a close communication between the different healthcare facilities, under a strict monitoring body, to prevent over burdening of the departments and smooth delivery of care to patients.
1.1. 导语:COVID-19大流行影响了每个部门的活动,但最明显的是卫生部门。了解和量化对医疗保健的任何此类影响对于更好的未来规划至关重要。1.2. 目的:我们采用去识别的回顾性数据,1)量化胸外科常见手术的流行情况,2)调查新冠肺炎疫情对我科患者特征、胸外科手术数量和比例的影响,3)寻找可能的原因。1.3. 材料和方法:我们使用了2018年12月至2021年7月期间在Hayatabad医疗中心胸外科手术的患者的HIPPA投诉回顾性数据,以确定大流行期间对胸外科手术数量和种类的影响。1.4. 结果:我们的资料共包括242例病例。大流行期间,胸外科手术总数增加了53%。流行率排名前五的胸外科手术分别是去皮术(34.2%)、包虫囊切除术(10.8%)、急诊开胸术(7%)、食管切除术(5.7%)和喂养式空肠吻合术(5.7%)。在大流行期间,胸部手术通常在男性和相对年轻的患者(年龄≤10岁)中更为普遍。我们看到肿瘤适应症的手术比例显著下降。然而,病例的基线特征、并发症和死亡率没有明显变化。1.5. 结论:尽管这次大流行对我们的基线特征以及手术的安全性和有效性没有显著影响,但其他医院的患者计划外转移导致我们科室的负担突然增加。我们建议在一个严格的监督机构下,在不同的医疗机构之间进行密切的沟通,以防止部门负担过重,并顺利向患者提供护理。
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引用次数: 0
Sub-Capsular Hematoma of the Liver Complicating Preeclampsia 肝包膜下血肿并发子痫前期
Pub Date : 2022-01-01 DOI: 10.47829/ajsccr.2022.6302
Khalloufi C, Kawtari S, Jalal M, Lamrissi A, Bouhya S
Subcapsular hematoma of the liver Subcapsular hematoma of the liver (SCLH) is defined as an anatomical-clinical entity corresponding to the appearance of a hematic collection located between the intact GLISSON capsule and the hepatic parenchyma. It is a rare complication of pregnancy with a high maternal-fetal mortality, occurring most often in the context of pre-eclampsia or HELLP syndrome (Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome). We report the case of a 25-year-old parturient, primiparous woman, with no previous history, admitted to the emergency room for shock in a 29-week amenorrhea pregnancy. Ultrasound examination revealed a ruptured sub capsular hematoma of the liver. An urgent surgical exploration was required, during which a rupture of the subcapsular hematoma of the liver was revealed, accompanied by a state of hemorrhagic shock. The management consisted in a polytransfusion with suture of the hepatic lesion without paking. The evolution was favorable with clinico-biological normalization and the patient was declared discharged at D10 of her hospitalization.
肝包膜下血肿肝包膜下血肿(SCLH)被定义为一种解剖学-临床实体,与位于完整GLISSON囊和肝实质之间的血肿相对应。这是一种罕见的妊娠并发症,母胎死亡率高,最常见于先兆子痫或HELLP综合征(溶血、肝酶升高和低血小板综合征)。我们报告的情况下,25岁的产妇,初产妇,没有以往的历史,承认休克在29周闭经妊娠急诊室。超声检查显示肝包膜下血肿破裂。需要紧急手术探查,期间发现肝包膜下血肿破裂,伴有失血性休克状态。治疗的方法是多路输血并缝合肝病变而不进行填塞。随着临床生物学的正常化,病情的发展是有利的,患者在住院第10天宣布出院。
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引用次数: 0
Application of a Research-Based Quality Control Circle for the Construction of a Three-Level Linkage Continuous Nursing Model of “Hospital-Cadre’s Sanatorium-Family” for Veteran Cadres 研究型质控圈在构建老干部“医院-干部疗养院-家庭”三级联动连续护理模式中的应用
Pub Date : 2022-01-01 DOI: 10.47829/ajsccr.2022.51301
Bao Rong, L. Dan, XiaoYu Xu, Zhang Jin Mei, Xiao Ying, G. Wei, Li Chun, Liu Li Yuan, Wang Fang, Lu Xiao Ying, Fang Jing Jing, Li Zhe, Mo Lin Fang
Objective: By carrying out research-based quality control circle activities, a continuous nursing model for hospitalized veteran cadres was built, which improved quality of life and compliance. Methods: A “Ji Dong Circle” quality control circle group was established to analyze the current situation, survey data, mine key points, and formulate strategies from three levels (hospital-cadre’s sanatorium-family), according to the operation steps of the subject research quality control circle. The quality control circle group was implemented from three aspects: the establishment of a three-level linkage management mode of “hospital-cadre’s sanatorium-family;” the establishment of “three more” nursing training modes; and the operation of a continuous nursing service system. Results: After implementation of the quality control circle, the level of relevant nursing professional knowledge among the nursing staff, the level of first aid skills among medical staff in cadre’s sanatorium, the coverage rate of telephone follow-up, nursing satisfaction, medication compliance of veteran cadres, and the living nursing operation level of caregivers were significantly improved compared to those before implementation (P<0.05). Conclusion: The research-based quality control circle activity constructed a new three-level linkage “hospital-cadre’s sanatorium-family” continuous nursing model for hospitalized veteran cadres that is guided by the needs of patients. At the same time, it has implemented the national medical security policy for the elderly, effectively improved the compliance and nursing satisfaction of the elderly cadres, and established the brand benefit of hospital elderly care services.
目的:通过开展研究型质控圈活动,建立住院老干部持续护理模式,提高生活质量和依从性。方法:建立“冀东圈”质控圈小组,根据课题研究质控圈的操作步骤,从医院-干部疗养院-家庭三个层面分析现状、调查数据、挖掘重点,制定对策。质控圈组从三个方面实施:建立“医院-干部疗养院-家庭”三级联动管理模式;建立“三多”护理培训模式;并形成了连续运行的护理服务体系。结果:质控圈实施后,干部疗养院护理人员相关护理专业知识水平、医护人员急救技能水平、电话随访覆盖率、护理满意度、老干部用药依从性、护理人员生活护理操作水平均较实施前显著提高(P<0.05)。结论:以研究型质控圈活动为基础,构建了以患者需求为导向的住院老干部“医院-干部疗养院-家庭”三级联动的连续护理新模式。同时,落实了国家老年人医疗保障政策,有效提高了老年干部的依从性和护理满意度,树立了医院养老服务的品牌效益。
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引用次数: 0
The Utility of 68Ga-DOTATOC PET/CT to Surface and Follow-up of Gastroenteropancreatic Neuroendocrine Tumors: A Case Report 68Ga-DOTATOC PET/CT在胃肠胰神经内分泌肿瘤表面及随访中的应用1例
Pub Date : 2022-01-01 DOI: 10.47829/ajsccr.2022.5501
Moreno-Monsalve T, Castellon-Sanchez Mi, Mohamed-Salem L, Hernandez-Martinez Ac, Frutos-Esteban L, Navarro-Fernandez Jl, Rodriguez-Locarno T, C. J.
Gastroenteropancreatic neuroendocrine tumors are characterized by specific tissue characteristics targeted by molecular imaging. Functional imaging is an important diagnostic tool because most NETs have high cell surface somatostatin receptor expression levels, which has a great impact on patient management, including better localization of occult tumors in the small intestine and pancreas as well as improved staging and restaging. We report the case of a male diagnosed with pancreatic neuroendocrine tumor, that during the follow-up a 68Ga-DOTATOC PET/CT scan revealed distant disease (bone and bowel), findings that conventional imaging did not reveal.
胃肠胰神经内分泌肿瘤具有分子成像靶向的特定组织特征。功能成像是一种重要的诊断工具,因为大多数NETs具有高细胞表面生长抑素受体表达水平,这对患者管理有很大影响,包括更好地定位小肠和胰腺的隐匿性肿瘤,以及改善分期和再分期。我们报告一例被诊断为胰腺神经内分泌肿瘤的男性病例,在随访期间,68Ga-DOTATOC PET/CT扫描显示远处病变(骨和肠),常规影像学未显示的结果。
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引用次数: 0
Least Square Analysis of Variance for the Assessment of Natural Consequences for Birth Weight, Weaning Weight, Yearling Weight, Pre-Weaning Daily Weight Acquire, and Greasy Fleece Weight of Kajli Sheep in Pakistan 巴基斯坦Kajli羊出生体重、断奶体重、初生体重、断奶前日增重和油羊毛体重自然影响评估的最小二乘方差分析
Pub Date : 2021-12-31 DOI: 10.47829/ajsccr.2021.31501
Farmanullah, Momen Khan, M. Salim, S. M. Hosseini, Sajid Ali, I. Rehman
The current study was completed to analyze the effect of natural components on various improvement affecting traits of Kajli sheep in Pakistan. For this reason, we apply two huge contemporary datasets in sheep to explore factors that influence the traits. Therefore, the generation information record of 13715 Kajli sheep lambing accumulated from 1994 to 2010 at Livestock Experimental Stations Khushab and Khizarabad, Punjab. Information records were genuinely analyzed through utilizing PC modified Mixed Model Harvey’s Least Squares and Maximum Likelihood. The two farms information data was analyzed by utilizing an animal model program. The factual model was incorporated to evaluate the Birth Weight (BW), 120 days at Weaning Weight (WW), Pre-Weaning Average Daily Gain (PRADG), Yearling Weight (YW) and Greasy Fleece Weight (GFW). Year of Birth (YOB), Birth Season (BS), Birth Types (BT) and sex was the fix effect in the model. Results indicated that, the overall general values for birth weight, weaning weight, yearling weight, pre-weaning weight and fleece weight were noted. Year of birth, type of birth, sex, and herd was influenced altogether significantly while, birth weight and greasy fleece weight, the period of birth showed no essential difference. In weaning weight and pre-weaning increment normally, year of birth, sort of birth and herd showed a critical contact except for sex. Male sheep were heavier than female sheep and single conceived sheep were also basically heavier than twins were during offspring birth. Results emulate that the Kajli sheep breed can be improved on through selection and further developed management. The cascade type of influence of the current investigation has levelheaded ramification not just for sheep farming by and by just as for intensified associate of boundaries which definitely convince deviation of weight, weight has become itself essential forecaster of in a matter of seconds wellness results. These outcomes displayed there are complex associations among hereditary qualities and ecological elements of parental, placental and fetal beginning. These are profoundly affected traits by maternal sustenance, genes, be concerned, the executive, environment, occasional diversity of seasons.
本研究旨在分析天然成分对巴基斯坦Kajli羊各种性状改良的影响。出于这个原因,我们应用了两个巨大的当代绵羊数据集来探索影响性状的因素。因此,对旁遮普省Khushab和Khizarabad畜牧实验站1994 - 2010年积累的13715头卡吉利羊羔的生养信息记录进行了分析。利用PC修正混合模型哈维最小二乘和极大似然对信息记录进行了真实分析。利用动物模型程序对两个农场的信息数据进行分析。采用事实模型对仔猪初生重(BW)、断奶120日重(WW)、断奶前平均日增重(PRADG)、初生重(YW)和油羊毛重(GFW)进行评价。出生年份(YOB)、出生季节(BS)、出生类型(BT)和性别是模型的固定效应。结果表明,仔猪初生重、断奶重、1龄重、断奶前重和起毛重的总体平均值均较高。出生年份、出生类型、性别和畜群均受显著影响,而出生重、油毛重、出生期无显著差异。断奶体重和断奶前增重正常情况下,除性别外,出生年份、出生种类和畜群表现出临界关系。公羊比母羊重,单胎羊在后代出生时也基本上比双胞胎重。结果表明,通过选育和进一步发展管理,可使卡伊利羊品种得到改良。目前调查的级联式影响不仅对养羊产生了冷静的影响,而且对边界的强化联系肯定会导致体重的偏差,体重本身已经成为几秒钟内健康结果的重要预测者。这些结果表明,遗传品质和亲本、胎盘和胎儿起始的生态因素之间存在复杂的关联。这些性状深受母亲的营养、基因、关心、执行、环境、偶尔的季节变化的影响。
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引用次数: 0
Reconstruction of The Hand in Congenital Polydactyly 先天性多指畸形的手部重建
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.31402
Koryukov Aa
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引用次数: 0
Shoulder Dislocation Reduction by the Novel Prakash’s Method 用新颖的普拉卡什方法复位肩部脱位
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.4102
Waqar M, Ullah I, Kabir S, Sanaullah, A. M
1. Objectives: The aim of this study is to evaluate the effectiveness of Prakash’s Method of relocation for dislocated shoulder. 1.2. Study Design: Descriptive Study. 1.3. Setting: Sports units of Hayatabad Medical Complex, Peshawar. 1.4. Method: 30patients (30 Shoulders) were recruited for study, all patients with signs symptoms of shoulder dislocation by clinical examination were subjected to anterior/ posterior shoulder radiograph. And those diagnosed with anterior shoulder dislocations were initially enrolled in the study. Reduction was performed using Prakash's method 1.5. Results: Prakash's method had success rate of 90.0% (n=27). In 10.0% (n=3) the reductions who failed were then reduced under anesthesia using the Hippocratic method. 50.0% (n=15) patients has mild pain, 36.7% (n=11) has moderate pain, and 13.3% (n=4) has severe pain during the procedure. All patients having mild and moderate pain were reduced successfully in the first attempt. 4 patients who has severe pain out of which 1 patient was reduced successfully and 3 patients were reduced by the Hippocratic method using anesthesia. The reduction time was ranging from 180-300 seconds with a mean of 216±85 seconds. no complication occurred during the procedure. 1.6. Conclusion: Prakash Method of shoulder relocation for acutely dislocated shoulder is an effective method.
1. 目的:本研究的目的是评估Prakash方法对肩部脱位的复位效果。1.2. 研究设计:描述性研究。地点:白沙瓦Hayatabad医疗中心的体育单位。方法:招募30例患者(30肩)进行研究,所有经临床检查有肩关节脱位症状的患者均行肩关节前后位x线片检查。那些被诊断为肩关节前脱位的人最初参与了这项研究。复位采用Prakash方法1.5。结果:Prakash法成功率为90.0% (n=27)。在10.0% (n=3)的减少失败,然后在麻醉下使用希波克拉底法减少。50.0% (n=15)的患者在手术过程中出现轻度疼痛,36.7% (n=11)的患者出现中度疼痛,13.3% (n=4)的患者出现重度疼痛。所有轻度和中度疼痛的患者在第一次尝试中均成功减轻。4例患者出现剧烈疼痛,其中1例成功减轻,3例患者采用希波克拉底法麻醉减轻。还原时间180 ~ 300秒,平均216±85秒。手术过程中无并发症发生。1.6. 结论:Prakash法肩关节复位是治疗急性肩关节脱位的有效方法。
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引用次数: 0
Huge Pedunculated Angiomyofibroblastoma Arising from The Valva: A Case Report with MR Findings and Review of the Literature 源自瓣膜的巨大带蒂血管肌纤维母细胞瘤:1例MR报告及文献复习
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.3602
Bo L
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引用次数: 0
期刊
American Journal of Surgery and Clinical Case Reports
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