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Coxsackie Virus Infection in A 61-Year-Old Female 一例61岁女性柯萨奇病毒感染病例
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.31001
Osuagwu Cc
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引用次数: 0
Epidemiological Study On the Prevalence of Road Traffic Accident and Associated Risk Factors Among Drivers in Bauchi State, Nigeria 尼日利亚包奇州道路交通事故发生率及相关危险因素的流行病学研究
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.3801
A. Aliyu, Nuru Yakubu Umar, Funmilayo Abubakar Sani, H. Mohammed
Ahmad Salisu Aliyu, Medical Laboratory Department Infectious Diseases Hospital (IDH) Kano, Nigeria, E-mail: salisuahmadaliyu@yahoo.com Received: 28 June 2021 Accepted: 19 July 2021 Published: 24 July 2021 Copyright: ©2021 Ahmad Salisu Aliyu, Nuru Yakubu Umar, Funmilayo Abubakar Sani, Hussaini Mohammed. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and build upon your work non-commercially.
Ahmad Salisu Aliyu,尼日利亚卡诺传染病医院(IDH)医学检验科,E-mail: salisuahmadaliyu@yahoo.com接收:2021年6月28日接收:2021年7月19日发布:2021年7月24日版权:©2021 Ahmad Salisu Aliyu, Nuru Yakubu Umar, Funmilayo Abubakar Sani, Hussaini Mohammed。这是一篇在知识共享署名许可条款下发布的开放获取文章,该许可允许不受限制地使用、分发和以您的作品为基础进行非商业使用。
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引用次数: 0
In Hospital Cost Assessment and Prevalence of Total Hip Arthroplasty in China: A10-Years Real-World Study 中国全髋关节置换术的医院成本评估和患病率:一项10年的真实世界研究
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.31202
Shakya H, Yuan M, Wang Hy, L. Z, Xiao K, Zhou Zk
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引用次数: 0
Zeehan Hospital, Zeehan, Tasmania. The First Forty Years, During The Mining Boom 1894-1934 The Curious Case of the Missing Lead Poisoning 泽汉医院,泽汉,塔斯马尼亚第一个四十年,在采矿业繁荣时期,1894-1934,失踪铅中毒的奇怪案例
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.31302
S. P.
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引用次数: 0
Acute Anus (Gallese’s Desease) 急性肛门(加勒斯氏病)
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.4101
Nando Gallese
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引用次数: 1
Gestational Diabetes Mellitus and Prisca Test for Increased Risk for Trisomy 21 And Other Aneuploidy in Pregnant Woman in Bitola in 2020 Year 2020年比托拉孕妇患21三体和其他非整倍体风险增加的妊娠糖尿病和Prisca试验
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.31401
Ilkovska B, Trifunova Bk, A. M, Avramovski P
Other Aneuploidy in Pregnant Woman in Bitola in 2020 Year Ilkovska B1*, Trifunova BK2, Avramovska M3 and Avramovski P4 1Department for Biomedical Biochemistry, PHO Clinical hospital Bitola, North Macedonia 2Department of dermato-venerology, Tokuda Hospital, Sofia, Bulgaria 3Department for genecology, PHO Clinical hospital Bitola, North Macedonia 4Department for Internal diseases, PHO Clinical hospital Bitola, North Macedonia
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引用次数: 0
Incidental Diagnosis of a High Grade Mucinous Neoplasm of the Appendix: A Case Report 阑尾高级别黏液性肿瘤的偶然诊断1例
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.31301
Dannaoui K, H. M, Young A, Clouse K, Gomez J, Matlin C, A. A.
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引用次数: 0
The Use Extracorporeal Membrane Oxygenation Therapy in A Severe Blunt Chest Trauma with A Main Tracheal Injury 体外膜氧合治疗严重钝性胸外伤伴主气管损伤的临床观察
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.31201
Zhang J, H. H, L. H, L. Y., W. M, C. X
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引用次数: 0
Rectourethral Fistula Management Via Urological Prospective 泌尿外科前瞻性治疗直肠尿道瘘
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.4202
Mazhar U. Khan, M. Iftikhar
Rectourethral fistula is a rare condition with multiple etiology. The surgical treatment is a challenge as the site is difficult to reach and also there are usually several associated comorbidities from the etiological cause which needs to be dealt with. This pathology involves different speciality i.e., general surgery, colorectal surgery, minimal access surgery, urology and reconstructive surgery etc. This being one of the reasons that several different surgical technique and approaches are devised to treat this condition. Our study is based on 19 patients in whom the etiology was trauma. The surgical approach was transperineal andwe utilizing scrotal fibrofatty vascularized flap for interposition layer. We had 89.5% (n=17) success rate and10.5% (n=2) recurrence. It is therefore concluded that perineal approach is safe and far less complication.It is also important to place vascularize interposition tissue flap for successful outcome.While more radical trans sphincteric approach with defunctional colostomy should only be reserved for more complex and recurrent cases.
摘要直肠尿道瘘是一种罕见的多病因性疾病。手术治疗是一个挑战,因为该部位难以到达,而且通常有一些相关的并发症,从病因需要处理。这种病理涉及不同的专业,即普通外科、结直肠外科、最小通道外科、泌尿外科和重建外科等。这是几种不同的手术技术和方法被设计来治疗这种情况的原因之一。我们的研究基于19例病因为创伤的患者。手术入路经会阴,以阴囊纤维脂肪血管化皮瓣为间置层。成功率为89.5% (n=17),复发率为10.5% (n=2)。结论会阴入路安全,并发症少。血管间置组织瓣的放置对手术的成功也很重要。而更根治性的经括约肌入路伴功能性结肠造口术应仅用于更复杂和复发的病例。
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引用次数: 0
GnRHa as A Treatment for Letrozole-Resistent Recurrent Adult Granulosa Cell Tumors:A Case Report and Literature Review GnRHa治疗来曲唑耐药复发性成人颗粒细胞瘤1例并文献复习
Pub Date : 2021-01-01 DOI: 10.47829/ajsccr.2021.31502
Y. H, Z. Y
1. Abstract Ovarian Granulosa Cell Tumors (GCTs) are the most common type of ovarian sex cord-stromal tumor. They follow an indolent course and are characterized by a long natural history The optimal management of Recurrent GCT has never been determined by randomized trials ,Hormone therapy maybe an alternative here we report a case of Recurrent GCT treated with GnRHa and achieved clinical cure.A 46-year-old woman presented with third recurrence after primary treatment for adult granulosa cell tumor. She developed tumor progression and drug-induced nephritis after 6 cycles of TP chemotherapy for the second recurrence and failed to benefit from chemotherapy, after the third Optimal cytoreduction and tumor progression after Letrozole treatent for 6 months. we try to Experimental treatment with Diphereline achieved Good therapeutic effect. 2. Highlights • There is no optimal treatment for recurrent granulocell tumor. For this patient, we tried to use hormone therapy replace of chemotherapy and radiotherapy. • Considering the different mechanisms of action of Letrozole and GnRHa, we tried GnRHa treatment after letrozole resistance. • The literature reported that letrozole had the highest response rate, but this patient still benefited from GnRHa even after letrozole resistance, as we know, no similar case has been reported. 3. Introduction Granulosa cell tumors constitute less than 5% of all ovarian tumors. Unlike epithelial ovarian tumors, they occur in a younger age group, are usually detected in an early stage. They follow an indolent course and are characterized by a long natural history. Due to the chance of recurrence even years after apparent clinical cure of the primary tumor, lifelong follow up is recommended. About 25 % GCT develop recurrence and the median time to recur is usually 4–5 years [1]. Most recurrences are intraperitoneal and usually a complete debulking of the disease is feasible even in the recurrent setting. Postoperative chemotherapy (platinum based) is usually given after surgery more so in cases with widespread disease or after sub-optimal cytoreduction. Recurrent chemoresistant, progressive non-responding GCT or patients with high surgical risk are ideal candidates for targeted therapy [2]. During the last decade, our understanding of the molecular pathogenesis of AGCTs has significantly improved, whereas the developments of chemotherapeutic regimens and targeted therapies have remained modest. Here we report a case of Recurrent Adult Granulosa cell tumors, after three times of cytoreduction, we use letrozole as postoperative treatment for 6 mouths, Radiographic findings showed recurrence, and letrozole resistance was considered. We tried GnRHa treatment and achieved clinical cure. 4. Case Presentation The patient is a 46-year-old female with the third recurrence after primary treatment for adult granulosa cell tumor. 15 years ago, total abdominal hysterectomy, bilateral salpingo-oophorectomy
1. 卵巢颗粒细胞瘤(gct)是卵巢性索间质肿瘤中最常见的类型。复发性GCT的最佳治疗从未通过随机试验确定,激素治疗可能是另一种选择,在这里我们报告一例用GnRHa治疗并获得临床治愈的复发性GCT。一位46岁的女性在接受成人颗粒细胞瘤原发治疗后出现第三次复发。患者经6个周期TP化疗后出现肿瘤进展和药物性肾炎,第二次复发,第三次化疗后未能受益,来曲唑治疗6个月后细胞减少最佳,肿瘤进展。我们尝试用双酚林进行实验性治疗,取得了良好的治疗效果。2. •复发性粒细胞瘤没有最佳治疗方法。对于该患者,我们尝试用激素治疗代替化疗和放疗。•考虑到来曲唑与GnRHa的作用机制不同,我们在来曲唑耐药后尝试GnRHa治疗。•文献报道来曲唑反应率最高,但该患者在来曲唑耐药后仍受益于GnRHa,据我们所知,未见类似病例报道。3.颗粒细胞瘤在所有卵巢肿瘤中所占比例不到5%。与卵巢上皮性肿瘤不同,它们发生在较年轻的年龄组,通常在早期被发现。它们遵循一种惰性的过程,并以漫长的自然历史为特征。由于在原发肿瘤明显临床治愈数年后仍有复发的机会,建议终生随访。约25%的GCT复发,中位复发时间通常为4-5年[1]。大多数复发是腹腔内的,即使在复发的情况下,通常也可以完全消除疾病。术后化疗(以铂为基础)通常在手术后给予,在疾病广泛或细胞减少次优的情况下更是如此。复发性耐药、进展性无反应的GCT或手术风险高的患者是靶向治疗的理想选择[2]。在过去的十年中,我们对agct的分子发病机制的理解有了显著的提高,而化疗方案和靶向治疗的发展仍然适度。我们报告一例复发性成人颗粒细胞瘤,经3次细胞减少后,术后使用来曲唑治疗6个月,影像学显示复发,考虑来曲唑耐药。我们尝试了GnRHa治疗并取得了临床治愈。4. 患者为女性,46岁,成人颗粒细胞瘤原发治疗后第三次复发。15年前,腹部全子宫切除术,双侧输卵管卵巢切除术
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引用次数: 0
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American Journal of Surgery and Clinical Case Reports
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