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[Molecular cytogenetics in chronic lymphatic leukemia: differential diagnosis with other chronic B-lineage lymphoproliferative syndromes]. [慢性淋巴白血病的分子细胞遗传学:与其他慢性b系淋巴增生性综合征的鉴别诊断]。
Sangre
Pub Date : 1999-08-01
J A García Marco
{"title":"[Molecular cytogenetics in chronic lymphatic leukemia: differential diagnosis with other chronic B-lineage lymphoproliferative syndromes].","authors":"J A García Marco","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76513,"journal":{"name":"Sangre","volume":"44 4","pages":"269-72"},"PeriodicalIF":0.0,"publicationDate":"1999-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21447509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Multicolor spectral karyotyping (SKY) and its application to the cytogenetic diagnosis of multiple myeloma]. 多色光谱核型(SKY)及其在多发性骨髓瘤细胞遗传学诊断中的应用。
Sangre
Pub Date : 1999-08-01
J C Cigudosa, M J Calasanz, J L García Miranda
{"title":"[Multicolor spectral karyotyping (SKY) and its application to the cytogenetic diagnosis of multiple myeloma].","authors":"J C Cigudosa, M J Calasanz, J L García Miranda","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76513,"journal":{"name":"Sangre","volume":"44 4","pages":"301-4"},"PeriodicalIF":0.0,"publicationDate":"1999-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21447514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[In situ hybridization techniques. Basis and applications in hematologic neoplasias]. 原位杂交技术。血液肿瘤的基础及应用[j]。
Sangre
Pub Date : 1999-08-01
B Espinet, E Lloveras, F Solé
{"title":"[In situ hybridization techniques. Basis and applications in hematologic neoplasias].","authors":"B Espinet, E Lloveras, F Solé","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76513,"journal":{"name":"Sangre","volume":"44 4","pages":"261-7"},"PeriodicalIF":0.0,"publicationDate":"1999-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21447508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Applications of fluorescence in situ hybridization (FISH) in acute lymphoblastic leukemia]. 荧光原位杂交(FISH)在急性淋巴细胞白血病中的应用
Sangre
Pub Date : 1999-08-01
J M Buades, E Vizcarra Rabadán, D Sánchez Izquierdo, J A Martínez-Climent
{"title":"[Applications of fluorescence in situ hybridization (FISH) in acute lymphoblastic leukemia].","authors":"J M Buades, E Vizcarra Rabadán, D Sánchez Izquierdo, J A Martínez-Climent","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76513,"journal":{"name":"Sangre","volume":"44 4","pages":"273-81"},"PeriodicalIF":0.0,"publicationDate":"1999-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21447510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Minimal residual disease. Methodologies and clinical implications]. [微小残留疾病。方法和临床意义]。
Sangre
Pub Date : 1999-08-01
M Ortega, M D Coll, F Solé, M R Caballín
{"title":"[Minimal residual disease. Methodologies and clinical implications].","authors":"M Ortega, M D Coll, F Solé, M R Caballín","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76513,"journal":{"name":"Sangre","volume":"44 4","pages":"283-90"},"PeriodicalIF":0.0,"publicationDate":"1999-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21447511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Application of CGH to the study of non-Hodgkin's lymphomas]. [CGH在非霍奇金淋巴瘤研究中的应用]
Sangre
Pub Date : 1999-08-01
E Arranz, J Benítez
{"title":"[Application of CGH to the study of non-Hodgkin's lymphomas].","authors":"E Arranz, J Benítez","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76513,"journal":{"name":"Sangre","volume":"44 4","pages":"297-300"},"PeriodicalIF":0.0,"publicationDate":"1999-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21447513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comparative genomic hybridization. Methodologic features]. 比较基因组杂交。方法学特征)。
Sangre
Pub Date : 1999-08-01
J L García, N C Gutiérrez, J M Hernández, M A Sánchez, M B González, J L Arroyo, J F San Miguel
{"title":"[Comparative genomic hybridization. Methodologic features].","authors":"J L García, N C Gutiérrez, J M Hernández, M A Sánchez, M B González, J L Arroyo, J F San Miguel","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76513,"journal":{"name":"Sangre","volume":"44 4","pages":"291-6"},"PeriodicalIF":0.0,"publicationDate":"1999-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21447512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hemorrhagic complications from anticoagulant treatment: analysis of predictive risk factors]. 抗凝治疗的出血性并发症:预测危险因素分析。
Sangre
Pub Date : 1999-06-01
E Vázquez Ruiz de Castroviejo, M del Monte Trujillo Pérez, C Lozano Cabezas, C Avellaneda Molina, M Guzmán Herrera, E Martínez Galiano, H Pousibet Sanfeliú, A Tarabini Castellani, C Pagola Vilardebó, A Alcalá Muñoz

Unlabelled: Anticoagulant therapy has shown its efficacy in the prevention of thromboembolic complications but it is not devoid of bleeding complications. Although the thromboembolic risk of some cardiac diseases may be extrapolated from well-organized clinical trials, the risk of bleeding complications should be determined in the context of the environment in which it is carried out.

Objective: To determine the complications of the patients in anticoagulant therapy, in our environment, and to analyse the of risk factors.

Patients and methods: We have studied the complications suffered by 300 patients who underwent anticoagulation for cardiac diseases, between March-94 and March-96 retrospectively. We have classified the complications in two groups: a) Fatal or intracranial with sequelae. b) Those requiring hospitalization and/or transfusion. Univariate and multivariant analyses were conducted to identify predictors of complications, including the following factors: age, sex, diabetes, hypertension, length of therapy, distance from our Center to their place of residence, INR (> 3 vs 2 to 3) and number of drugs associated with Acenocoumarol (> or = 3 vs 2 or less).

Results: During the follow-up 24 patients died due to non haemorrhagic complications; 3 left the treatment on their cardiologist recommendation; 2 moved their place of residence and 1 was lost in the follow-up. Of 270 remaining 3 (0.55/100 patients-year) had complications of group a and 21 (3.88/100 patients-year) of grub b. INR > 3 and multiple medications were shown as predictors of complications when including some of the complications considered.

Conclusions: 1) During two years of follow-up 1.1% (0.55/100 patients-year) of patients in anticaogulant therapy had bleeding complications resulting in death or neurological sequelae. 2) When including some of the complications considered the percentage rises to 4.44/100 patients-years. 3) Although there were no differences statistically significant, INR > 3 and polymedication have been found as predictors risk factor. 4) Patients with INR of 2 to 3 and non polymedicated presented a low risk of bleeding complications (1.66/100 patients-year).

未标记:抗凝治疗已显示其预防血栓栓塞并发症的功效，但它并非没有出血并发症。虽然一些心脏疾病的血栓栓塞风险可以从组织良好的临床试验中推断出来，但出血并发症的风险应该在进行试验的环境背景下确定。目的:了解环境下抗凝治疗患者并发症的发生情况，并分析其危险因素。患者与方法:回顾性分析了1994年3月至1996年3月间300例因心脏疾病行抗凝治疗的患者的并发症。我们将并发症分为两组:a)致死性或颅内伴后遗症。b)需要住院和(或)输血的患者。进行单变量和多变量分析以确定并发症的预测因素，包括以下因素:年龄、性别、糖尿病、高血压、治疗时间、离我们中心的距离、INR (> 3 vs 2 ~ 3)和与阿塞诺库马洛相关的药物数量(>或= 3 vs 2或更少)。结果:随访中24例患者死于非出血性并发症;3人按照心脏病专家的建议接受治疗;2人迁居，1人在随访中失踪。270例患者中有3例(0.55/100例患者-年)出现a组并发症，21例(3.88/100例患者-年)出现b组并发症。当考虑到一些并发症时，INR > 3和多种药物治疗被认为是并发症的预测因素。结论:1)2年随访期间，1.1%(0.55/100例患者-年)的抗凝治疗患者出现出血并发症导致死亡或神经系统后遗症。2)当考虑到一些并发症时，这一比例上升到4.44/100患者-年。3)虽无统计学差异，但INR > 3和多药治疗可作为预测危险因素。4) INR为2 ~ 3且未多药的患者出血并发症风险较低(1.66/100患者-年)。
{"title":"[Hemorrhagic complications from anticoagulant treatment: analysis of predictive risk factors].","authors":"E Vázquez Ruiz de Castroviejo,&nbsp;M del Monte Trujillo Pérez,&nbsp;C Lozano Cabezas,&nbsp;C Avellaneda Molina,&nbsp;M Guzmán Herrera,&nbsp;E Martínez Galiano,&nbsp;H Pousibet Sanfeliú,&nbsp;A Tarabini Castellani,&nbsp;C Pagola Vilardebó,&nbsp;A Alcalá Muñoz","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Unlabelled: </strong>Anticoagulant therapy has shown its efficacy in the prevention of thromboembolic complications but it is not devoid of bleeding complications. Although the thromboembolic risk of some cardiac diseases may be extrapolated from well-organized clinical trials, the risk of bleeding complications should be determined in the context of the environment in which it is carried out.</p><p><strong>Objective: </strong>To determine the complications of the patients in anticoagulant therapy, in our environment, and to analyse the of risk factors.</p><p><strong>Patients and methods: </strong>We have studied the complications suffered by 300 patients who underwent anticoagulation for cardiac diseases, between March-94 and March-96 retrospectively. We have classified the complications in two groups: a) Fatal or intracranial with sequelae. b) Those requiring hospitalization and/or transfusion. Univariate and multivariant analyses were conducted to identify predictors of complications, including the following factors: age, sex, diabetes, hypertension, length of therapy, distance from our Center to their place of residence, INR (> 3 vs 2 to 3) and number of drugs associated with Acenocoumarol (> or = 3 vs 2 or less).</p><p><strong>Results: </strong>During the follow-up 24 patients died due to non haemorrhagic complications; 3 left the treatment on their cardiologist recommendation; 2 moved their place of residence and 1 was lost in the follow-up. Of 270 remaining 3 (0.55/100 patients-year) had complications of group a and 21 (3.88/100 patients-year) of grub b. INR > 3 and multiple medications were shown as predictors of complications when including some of the complications considered.</p><p><strong>Conclusions: </strong>1) During two years of follow-up 1.1% (0.55/100 patients-year) of patients in anticaogulant therapy had bleeding complications resulting in death or neurological sequelae. 2) When including some of the complications considered the percentage rises to 4.44/100 patients-years. 3) Although there were no differences statistically significant, INR > 3 and polymedication have been found as predictors risk factor. 4) Patients with INR of 2 to 3 and non polymedicated presented a low risk of bleeding complications (1.66/100 patients-year).</p>","PeriodicalId":76513,"journal":{"name":"Sangre","volume":"44 3","pages":"216-21"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21345016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Lymphoma of the mandible: presentation of 2 cases]. 下颌骨淋巴瘤:附2例报告。
Sangre
Pub Date : 1999-06-01
M A Canales Albendea, M T Alvarez Román, I del Pozo Pozo, F Hernández Navarro
{"title":"[Lymphoma of the mandible: presentation of 2 cases].","authors":"M A Canales Albendea,&nbsp;M T Alvarez Román,&nbsp;I del Pozo Pozo,&nbsp;F Hernández Navarro","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76513,"journal":{"name":"Sangre","volume":"44 3","pages":"243-4"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21345026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Severe esophageal stenosis secondary to the administration of chemotherapy in a patient with acute myeloblastic leukemia]. [急性髓细胞白血病患者化疗后继发严重食管狭窄]。
Sangre
Pub Date : 1999-06-01
M A Canales Albendea, M T Alvarez Román, R Villanueva Pavón, F Hernández Navarro
{"title":"[Severe esophageal stenosis secondary to the administration of chemotherapy in a patient with acute myeloblastic leukemia].","authors":"M A Canales Albendea,&nbsp;M T Alvarez Román,&nbsp;R Villanueva Pavón,&nbsp;F Hernández Navarro","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76513,"journal":{"name":"Sangre","volume":"44 3","pages":"245-6"},"PeriodicalIF":0.0,"publicationDate":"1999-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21345027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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