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Local treatment of colpitis with Betadine vaginal suppository. 倍他定阴道栓剂局部治疗阴道炎。
Pub Date : 1993-01-01
B A Resch, F Szántó

Observations made with Betadine vaginal suppository in the treatment of 60 women suffering from colpitis have been discussed. The results of microbiological examinations of vaginal discharge sampled before 1 week and 4 weeks after the onset of therapy were compared. The effectiveness, tolerance of therapy, and the subjective opinion of the treated women were analysed. According to the results of the examinations in response to Betadine vaginal suppository the positivity of vaginal discharge for Candida decreased from 16 to 3 cases, for Trichomonas from 8 to 1 case, for aerobic bacteria from 16 to 7 cases, and the occurrence of mixed infections from 20 to 2 cases. Subjective complaints, burning, stinging sensation were rapidly moderated. In 52 of the 60 women discharge ceased, in another 4 cases it significantly decreased. In 51 cases burning sensation in the vagina ceased, and in 5 women it significantly decreased. Recurrence was not observed when a control examination was done after 1 month. The women tolerated Betadine vaginal suppository well and found it effective and easily applicable. At the beginning of treatment burning sensation was aggravated in 3 cases. These patients refused to further participate in the examination and received systemic treatment. Due to its broad bactericidal, fungicidal, protozoicide action and its good tolerability Betadine suppository was found to be useful for the local treatment of colpitis.

观察比他定阴道栓剂在治疗60名妇女患阴道炎进行了讨论。比较治疗前1周和治疗后4周阴道分泌物的微生物学检查结果。分析了治疗的有效性、耐受性和治疗妇女的主观意见。经倍他定阴道栓剂检查,阴道分泌物念珠菌阳性由16例下降到3例,滴虫阳性由8例下降到1例,需氧菌阳性由16例下降到7例,混合性感染由20例下降到2例。主观主诉、灼烧感、刺痛感迅速减轻。60名妇女中有52名停止了出院,另外4名明显减少。51例阴道烧灼感消失,5例明显减轻。1个月后进行对照检查,未见复发。妇女对倍他定阴道栓剂耐受性好,效果好,使用方便。治疗初期有3例患者烧灼感加重。这些患者拒绝进一步参与检查,接受全身治疗。由于其广泛的杀菌、杀真菌、杀原虫作用和良好的耐受性,他定栓被发现可用于局部治疗阴道炎。
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引用次数: 0
Comparative clinical examination of Loderix (setastinum) and astemizole in pollenosis. 洛德里克斯与阿司咪唑治疗花粉症的临床比较研究。
Pub Date : 1993-01-01
I Herjavecz, E Karácsonyi, S Mülbacher, K Radics, R Szilágyi, I Gacsályi

The action and side-effects of Loderix (EGIS) were examined in comparison with Hismanal (Janssen) containing the non-sedative H1-receptor antagonist astemizole, by double-blind, cross-over, self-controlled method. On the basis of the changes observed in response to the two drugs in the symptoms of rhinoconjunctivitis and asthma of 21 patients suffering from pollenosis Loderix proved to be of the same value as Hismanal considering both clinical effectivity and side-effects.

采用双盲、交叉、自控的方法,将Loderix (EGIS)与含有非镇静h1受体拮抗剂阿司咪唑的Hismanal (Janssen)进行比较。通过观察两种药物对21例花粉症患者鼻结膜炎和哮喘症状的反应变化,证明在临床疗效和副作用方面,Loderix与Hismanal具有相同的价值。
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引用次数: 0
Arduan relaxation following norcuron intubation. 正常插管后的Arduan松弛。
Pub Date : 1993-01-01
T Fister

Norcuron injection was administered before intubation in the course of anaesthesia in 57 gynaecological operations. Surgical relaxation was performed with Arduan. The patients received varying premedication, introduction, and maintenance narcosis. The combined use of the two non-depolarizing neuromuscular blocking agents proved to be favourable and useful from the anaesthesiological aspect.

在57例妇科手术中,插管前注射诺库隆。用Arduan进行手术放松。患者接受不同的药物治疗前、引入和维持麻醉。两种非去极化神经肌肉阻滞剂的联合使用从麻醉角度证明是有利的和有用的。
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引用次数: 0
The use of Paxirasol in clinical practice. 帕西拉索尔在临床中的应用。
Pub Date : 1993-01-01
G Nagy

Summarizing the observations of foreign and Hungarian investigators it may be concluded that: 1. Bromhexine is an expectorant of outstanding effect which has virtually no side-effects when used in therapeutic doses; by loosening the thick, sticky mucus in increases the effectivity of mucociliary clearance and hinders the infection of thick excretion sticking to the mucosa. 2. It promotes the diffusion of antibiotics into the lung tissue. 3. Considering the increasingly important aspects of "cost-benefit", the use of drug is also advantageous. 4. In addition to the traditional drug forms (tablet, injection, solution) new forms of the drug (inhalation aerosol, nasal spray) increase its indication field to a high degree. These allow to apply local expectorant-mucolytic therapies and to successfully treat the so-called sicca diseases (rhinitis sicca, pharyngitis sicca, etc.), which frequently occur in laryngological practice and was difficult to influence until present.

总结外国和匈牙利调查人员的意见,可以得出以下结论:溴克辛是一种祛痰剂,效果显著,治疗剂量时几乎没有副作用;通过松动粘稠的黏液,增加了纤毛粘膜清除的有效性,并阻碍粘稠排泄物粘在粘膜上的感染。2. 它促进抗生素扩散到肺组织。3.考虑到越来越重要的“成本效益”方面,使用药物也是有利的。4. 除传统剂型(片剂、注射剂、溶液)外,新剂型(吸入性气雾剂、鼻喷雾剂)使其适应证领域高度增加。这些方法可以应用局部祛痰-溶黏液疗法,并成功治疗所谓的干燥病(干燥鼻炎、干燥咽炎等),这些疾病在喉科实践中经常发生,直到现在都难以影响。
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引用次数: 0
Clinical results with Taleum in the treatment of extrinsic bronchial asthma. Taleum治疗外源性支气管哮喘的临床效果。
Pub Date : 1993-01-01
G Alexy, F Sárdi

Taleum inhalation aerosol, produced by EGIS Pharmaceuticals Works, was examined in an 8-week open cross-over self-controlled study in 50 patients suffering from extrinsic bronchial asthma. Intal powder capsule inhaled with the aid of a spinhaler was used as a reference drug. Changes in subjective complaints and symptoms were continuously recorded on a score scale in the patients' diary. The alterations in respiratory parameters were measured. Laboratory parameters were monitored. On the basis of the results Taleum spray was found to be effective in the prevention of bronchial asthma. It proved to be a well tolerated drug form of simple use.

EGIS制药厂生产的talum吸入气雾剂,在50例外源性支气管哮喘患者中进行了为期8周的开放交叉自我对照研究。用旋吸器辅助吸入粉状胶囊作为对照药。主观主诉和症状的变化连续记录在患者日记的评分量表上。测量呼吸参数的变化。监测实验室参数。在此基础上,发现Taleum喷雾剂对支气管哮喘有较好的预防作用。它被证明是一种耐受性良好的药物形式,使用简单。
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引用次数: 0
Effect of superovulation combination therapy containing Clostilbegyt (clomiphene citrate) on follicular development and the endometrium. 含Clostilbegyt(柠檬酸克罗米芬)的超排卵联合治疗对卵泡发育和子宫内膜的影响。
Pub Date : 1993-01-01
I Cseh, G Perkedi, S Drávucz, J Demeter, G Juhász, I Rákóczi, I Gáti

The effect of Clostilbegyt + Humegon + Pregnyl ovulation inductive combination therapy was examined in the woman members of 20 sterile couples appearing at the Outpatient Department of Cryospermatology, Department of Obstetrics and Gynaecology Postgraduate Medical School. In 18 of the 20 cases follicle maturation and ovulation could be induced. In the male members of the couples therapy-resistant sterility existed at the same. By using artificial insemination by donors with cryopreserved sperms, gravidity could be obtained in 14 cases. The importance of the optimal timing of AID has been emphasized. In the course of transvaginal ultrasonography folliculometry was completed with the control of the pre-ovulatory changes of the endometrium. The appearance of the pre-ovulatory ring preceded the occurrence of pregnancy in all cases, being a sign of predictive value considering conception.

研究了Clostilbegyt + Humegon + Pregnyl诱导排卵联合治疗在妇产科研究生院冷冻精科门诊就诊的20对不育夫妇中的女性成员的效果。20例中有18例可诱导卵泡成熟和排卵。在这些夫妇中的男性成员中,治疗抵抗性不育症同样存在。用冷冻精子供体人工授精,14例成功受孕。强调了援助的最佳时机的重要性。在经阴道超声检查过程中,在控制排卵前子宫内膜变化的情况下完成卵泡测定。在所有情况下,排卵前环的出现都先于怀孕的发生,是考虑受孕的预测价值的标志。
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引用次数: 0
Clinico-bacteriological examination of Betadine skin disinfectant fluid and liquid soap in hospitalized patients and hospital employees. 住院病人和医院职工倍他定皮肤消毒液和洗手液的临床细菌学检查。
Pub Date : 1993-01-01
T Major, M Major, C Bognár, A Herendi, M Németh, B Bánkuti

The effectivity of Betadine skin and mucosa disinfectant solution and Betadine hand disinfectant soap (MUNDIPHARMA A. G. and EGIS Pharmaceuticals has been examined in hospitalized patients and hospital employees. The history of the production of polyvynilpyrrolidone-iodine (PVP-Iodine) the mechanism of actions and the biological effects of these products have been discussed. Bacteriological samples were collected from the skin of four regions most frequently used for injection (fossa cubitalis, right and left hands and gluteal region, right and left sides) of 10 hospitalized patients before and after washing these regions with Betadine. The average of 68 microorganisms Colony Forming Unit (CFU) recorded before disinfection decreased below 1 CFU on average in the samples taken after disinfection. From both hands of 6 hospital employees 190 CFUs could be demonstrated following washing hands with the commonly used soap. After washing hands with Betadine soap a total of 1 CFU could be demonstrated. The hands of 44 hospital employees were infected with E. coli of non-pathogenous reference strain whereafter samples were collected. After the disinfection of the hands with Betadine liquid soap samples were taken again. In the samples taken before disinfection an average of 745 CFUs, in samples taken after disinfection an average total of 11 CFUs were found. The results prove the outstanding disinfectant action of the two examined Betadine products.

在住院患者和医院工作人员中检测了倍他定皮肤粘膜消毒液和倍他定手部消毒皂(MUNDIPHARMA a.g.和EGIS Pharmaceuticals)的有效性。介绍了聚吡咯烷酮碘(pvp -碘)的生产历史、作用机理和生物效应。用倍他定清洗10例住院患者最常注射的4个部位(肘窝、右手和左手、臀区、左右两侧)的皮肤前后进行细菌学检测。消毒前记录的68个微生物菌落形成单位(CFU)在消毒后的样品中平均下降到1个以下。在用常用肥皂洗手后,6名医院员工的双手可显示出190个cfu。用比他定洗手液洗手后,总共可以显示1个CFU。对44例医院职工手部感染非致病性参比菌株大肠杆菌进行采集。手用倍他定液消毒后,再次采集样本。消毒前样本中平均含有745个cfu,消毒后样本中平均含有11个cfu。结果表明,两种检测产品均具有良好的杀菌作用。
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引用次数: 0
The role of nitroglycerin preparations in the treatment of post-acute and chronic pancreatitis. 硝酸甘油制剂在急性和慢性胰腺炎后治疗中的作用。
Pub Date : 1993-01-01
Z Berger, A Pap

The role of nitrate compounds in the therapy of pancreatic diseases is discussed in this review. A short overview is given about the physiological background of the treatment: the regulation of Oddi's sphincter function and its pharmacology. An adjuvant role is attributed to the free outflow of pancreatic secretion in the treatment of pancreatic pain and in the prevention of relapses. The authors describe their clinical practice during the last 15 years: nitrates with short half-life in the treatment of acute pancreatitis (amylnitrit or nitroglycerin spray) which have a low risk of developing nitrate tolerance; chronic administration of retard nitroglycerin in chronic pancreatitis and Oddi's sphincter hypertonic dyskinesia. For preventing the induction of nitrate tolerance, Nitromint retard is recommended twice a day combined with a calcium antagonist or with theophylline during the nitrate-free period.

现就硝酸盐类化合物在胰腺疾病治疗中的作用作一综述。简要概述了治疗的生理背景:Oddi的括约肌功能的调节及其药理学。胰腺分泌物的自由流出在治疗胰腺疼痛和预防复发中起辅助作用。作者描述了他们在过去15年的临床实践:半衰期短的硝酸盐治疗急性胰腺炎(氨基硝基或硝酸甘油喷雾)具有低风险的硝酸盐耐受性;慢性胰腺炎和Oddi氏括约肌高张性运动障碍的慢性迟滞硝酸甘油治疗。为了防止硝酸盐耐受的诱导,在无硝酸盐期间,建议每天两次硝基薄荷缓蚀剂与钙拮抗剂或茶碱联合使用。
{"title":"The role of nitroglycerin preparations in the treatment of post-acute and chronic pancreatitis.","authors":"Z Berger,&nbsp;A Pap","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The role of nitrate compounds in the therapy of pancreatic diseases is discussed in this review. A short overview is given about the physiological background of the treatment: the regulation of Oddi's sphincter function and its pharmacology. An adjuvant role is attributed to the free outflow of pancreatic secretion in the treatment of pancreatic pain and in the prevention of relapses. The authors describe their clinical practice during the last 15 years: nitrates with short half-life in the treatment of acute pancreatitis (amylnitrit or nitroglycerin spray) which have a low risk of developing nitrate tolerance; chronic administration of retard nitroglycerin in chronic pancreatitis and Oddi's sphincter hypertonic dyskinesia. For preventing the induction of nitrate tolerance, Nitromint retard is recommended twice a day combined with a calcium antagonist or with theophylline during the nitrate-free period.</p>","PeriodicalId":76737,"journal":{"name":"Therapia Hungarica (English edition)","volume":"41 2","pages":"72-7"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19267306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Jenö Jendrassik and the beginnings of experimental physiology in Hungary. Jenö Jendrassik和匈牙利实验生理学的开始。
Pub Date : 1993-01-01
{"title":"Jenö Jendrassik and the beginnings of experimental physiology in Hungary.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76737,"journal":{"name":"Therapia Hungarica (English edition)","volume":"41 2","pages":"78-80"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19267307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical observations with Paxirasol aerosol in patients suffering from chronic bronchitis accompanying silicosis. 帕西拉索尔气雾剂治疗慢性支气管炎伴矽肺的临床观察。
Pub Date : 1992-01-01
G Alexy, I Lukács, F Sárdi

Paxirasol aerosol applied in daily 3 x 5 puff doses in the treatment of silicosis patients is found to be a well tolerated drug form. In the course of the 21-day therapy especially coughing and chest pain were moderated, but the product also controlled, the catarrhal coat formation on the mucosa. It influenced abundant expectoration and dispnoea beneficially. During the therapy the laboratory parameters did not change. The objective respiratory parameters improved but the change was non-significant. Paxirasol aerosol is found useful in the treatment of chronic bronchitis accompanying silicosis. Evaluable side-effects were not registered.

帕西拉索尔气雾剂应用于每日3 x 5雾化剂量在矽肺患者的治疗被发现是一种良好的耐受药物形式。在21天的治疗过程中,咳嗽和胸痛有所减轻,但本品也控制了粘膜上的卡他性外套的形成。它有利于祛痰和祛痰。在治疗期间,实验室参数没有改变。客观呼吸参数有所改善,但变化不显著。帕西拉索尔气雾剂被发现在治疗慢性支气管炎伴矽肺病有用。未记录可评估的副作用。
{"title":"Clinical observations with Paxirasol aerosol in patients suffering from chronic bronchitis accompanying silicosis.","authors":"G Alexy,&nbsp;I Lukács,&nbsp;F Sárdi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Paxirasol aerosol applied in daily 3 x 5 puff doses in the treatment of silicosis patients is found to be a well tolerated drug form. In the course of the 21-day therapy especially coughing and chest pain were moderated, but the product also controlled, the catarrhal coat formation on the mucosa. It influenced abundant expectoration and dispnoea beneficially. During the therapy the laboratory parameters did not change. The objective respiratory parameters improved but the change was non-significant. Paxirasol aerosol is found useful in the treatment of chronic bronchitis accompanying silicosis. Evaluable side-effects were not registered.</p>","PeriodicalId":76737,"journal":{"name":"Therapia Hungarica (English edition)","volume":"40 4","pages":"180-4"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12517328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Therapia Hungarica (English edition)
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