Annales de l'Institut Pasteur. Virology最新文献

{"title":"Epidemiology of rotavirus subgroups and serotypes in Belem, Brazil: A three-year study","authors":"A.C. Linhares ,&nbsp;Y.B. Gabbay ,&nbsp;J.D.P. Mascarenhas ,&nbsp;R.B. Freitas ,&nbsp;T.H. Flewett ,&nbsp;G.M. Beards","doi":"10.1016/S0769-2617(88)80009-1","DOIUrl":"10.1016/S0769-2617(88)80009-1","url":null,"abstract":"<div><p>Rotavirus subgroups and serotypes were determined in 61 rotavirus-positive faecal samples obtained from children living in Belém, Brazil, followed up from birth to 3 years of age. Fifty-five (90%) of the specimens were subgrouped and the serotypes of 30 (49%) of them were determined. Subgroup II was detected in 49 (89%) of the 55 subgrouped strains. Serotype 1 was present in 15 (50%) of, the 30 serotyped samples; serotypes 2, 3 and 4 were found in 30%, 3.3% and 16.7% respectively, of these specimens. Absence of Vp7, the major outer capsid glycoprotein, did not allow serotyping in 21 (34.4%) of the 61 rotavirus-positive specimens, and an unidentifiable new serotype was found in faeces of one child. In addition, 4 samples were classified as subgroup II serotype 2 (which is very unusual).</p><p>Twelve (80%) of the 15 serotype 1 (subgroup II) specimens were collected from children (5 of them asymptomatic) during their first year of life. All 9 serotype 2 (subgroups I, II, or not determined) samples were detected during the second and third years of life, 7 (77.8%) of them were related to apparent infections. The 5 serotype 4 (subgroup II) samples were obtained throughout the study period, and were associated with both symptomatic (3 cases) and asymptomatic infections.</p><p>Thirteen children had more than 1 rotavirus infection. Three had 3 successive infections. In 3 cases, the initial infection (either symptomatic or asymptomatic) caused by serotype 1, was followed by a subsequent diarrhoeic episode associated with serotype 2.</p></div><div><p>Des enfants, suivis de la naissance jusqu'à l'âge de 3 ans, ont fourni 61 prélèvements fécaux, positifs pour les rotavirus. Le typage des souches a permis de déterminer le sous-groupe pour 55 (90%) d'entre elles et le sérotype pour 30 (49%).</p><p>Parmi les 55 rotavirus groupés, 49 (89%) appartenaient au sous-groupe II. Les sérotypes 1, 2, 3 et 4 sont présents respectivement chez 50 (15/30), 30, 3,3 et 16,7% des échantillons analysés. L'absence de Vp7 n'a pas permis la caractérisation de 21 (34,4%) spécimens, tandis qu'un sérotype peut-être nouveau a été mis en évidence dans les selles d'un enfant. Fait exceptionnel, quatre échantillons ont été classés dans le sous-groupe II, sérotype 2.</p><p>Parmi les 15 échantillons appartenant aux sérotype 1 (sous-groupe II), 12 (80%) ont été récoltés chez des enfants (dont 5 ne présentaient pas de symptômes) durant leur première année alors que toutes les souches de sérotype 2 (au nombre de 9, sous-groupes I, II ou indéterminé) ont été détectées au cours des deuxième et troisième années, 7 (77,8%) d'entre elles étant associées à des infections apparentes Les 5 souches de sérotype 4 (sous-groupe II) ont été obtenues durant toute la période d'étude, associées à des infections symptomatiques dans 3 cas.</p><p>Treize enfants ont montré des infections répétées à rotavirus. Chez 3 d'entre eux, 3 infections successives ont été notées. Une infection (accompagnée ou non de","PeriodicalId":77667,"journal":{"name":"Annales de l'Institut Pasteur. Virology","volume":"139 ","pages":"Pages 89-99"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0769-2617(88)80009-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13988207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}