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Battle of the Bots: Assessing the Ability of Four Large Language Models to Tackle Different Surgery Topics. 机器人之战:评估四种大型语言模型处理不同手术主题的能力。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2026-01-01 Epub Date: 2025-05-26 DOI: 10.1177/00031348251346538
M Madi, T Araji, D Hazimeh, Souheil W Adra

ObjectiveOur study aims to compare the performance of different large language model chatbots on surgical questions of different topics and categories.Materials and MethodsFour different chatbots (ChatGPT 4.0, Medical Chat, Google Bard, and Copilot Ai) were used for our study. 114 multiple-choice surgical questions covering 9 different topics were entered into each chatbot, and their answers were recorded.ResultsThe performance of ChatGPT was significantly better than Bard (P < 0.0001) and Medical Chat (P = 0.0013) but not significantly better than Copilot (P = 0.9663). We also found a statistically significant difference in ENT (P = 0.0199) and GI (P = 0.0124) questions between each chatbot when we assessed their performances per surgical specialty. Finally, the mean scores of Bard, Copilot, Medical Chat, and ChatGPT 4.0 on the diagnosis questions were higher than those in the management questions. The difference was only statistically significant, however, for Bard (P = 0.0281).ConclusionOur study offers insight into the performance of different chatbots on surgery-related questions and topics. The strengths and shortcomings of each can provide us with a better understanding of how to use Chatbots in the surgical field, including surgical education.

目的比较不同大语言模型聊天机器人在不同主题和类别的外科问题上的表现。材料与方法使用四种不同的聊天机器人(ChatGPT 4.0、Medical Chat、b谷歌Bard和Copilot Ai)进行研究。在每个聊天机器人中输入涵盖9个不同主题的114个外科选择题,并记录他们的答案。结果ChatGPT的性能显著优于Bard (P < 0.0001)和Medical Chat (P = 0.0013),但不显著优于Copilot (P = 0.9663)。当我们评估每个聊天机器人在每个外科专科的表现时,我们还发现每个聊天机器人在ENT (P = 0.0199)和GI (P = 0.0124)问题上存在统计学上的显著差异。最后,Bard、Copilot、Medical Chat和ChatGPT 4.0在诊断问题上的平均得分高于管理问题。然而,巴德组的差异仅具有统计学意义(P = 0.0281)。我们的研究深入了解了不同聊天机器人在手术相关问题和话题上的表现。每个人的优点和缺点可以让我们更好地了解如何在外科领域使用聊天机器人,包括外科教育。
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引用次数: 0
Characteristics of Long-Term Survivors With Peritoneal Mesothelioma - Insights From the National Cancer Database. 腹膜间皮瘤长期存活者的特征——来自国家癌症数据库的见解。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2026-01-01 Epub Date: 2025-06-17 DOI: 10.1177/00031348251350994
Himani Bhatt, Deep P Vakil, Luis Quintero, Monique Motta, Maria Vashchenko, Bettsy Rodriguez, Shenae K Samuels, Kumar Jayant, Jonathan Magloire, Christopher J Gannon, Omar H Llaguna

Introduction: Peritoneal mesothelioma (PM) is a rare cancer associated with high mortality. No studies exist using the National Cancer Database (NCDB) that have examined factors associated with long-term survival (LTS). Methods: NCDB 2006-2019 was queried for patients with PM. Primary objective was to determine the characteristics of LTS among patients with peritoneal mesothelioma. Secondary objective: identified predictors of LTS were then used to develop and internally validate a nomogram to predict the probability of LTS among patients. LTS was defined as 5 or more years of survival after diagnosis. Univariate and multivariate logistic analyses were performed. Results: The study included 3,636 patients with PM, 17.8% had LTS. The median survival time was 17.7 months. For LTS, the median survival time was ∼92 months while the median survival time of non-long-term survivors (NLTS) was 11.7 months. Following factors were common with LTS patients compared to the NLTS: female, younger, privately insured, treatment at academic/research institutions and treatment at high case volume institutions, Charlson-Deyo comorbidity score of 0, receiving radical surgery, receiving chemotherapy, greater proportion of grade 1 disease, negative lymph nodes, and lower rates of lymphovascular invasion (P < .001). The nomogram included age, gender, and surgical margins. Conclusion: A subset of PM patients can be long-term survivors with effective patient selection and appropriate care. This study highlights critical factors that influence LTS, paving the way for personalized treatment strategies and enhanced prognostication. Further research is needed to improve patient selection and ensure patients likely to be LTS receive adequate care.

腹膜间皮瘤(PM)是一种罕见的癌症,死亡率高。目前还没有使用国家癌症数据库(NCDB)的研究检查与长期生存(LTS)相关的因素。方法:查询NCDB 2006-2019中PM患者。主要目的是确定腹膜间皮瘤患者LTS的特征。次要目标:确定LTS的预测因子,然后用于开发和内部验证一个nomogram来预测LTS在患者中的概率。LTS定义为诊断后存活5年或更长时间。进行单因素和多因素逻辑分析。结果:共纳入PM患者3636例,其中LTS患者占17.8%。中位生存时间为17.7个月。对于LTS,中位生存时间为~ 92个月,而非长期幸存者(NLTS)的中位生存时间为11.7个月。与NLTS相比,LTS患者常见的因素有:女性、年轻、私人保险、在学术/研究机构治疗和在高病例量机构治疗、Charlson-Deyo合病评分为0、接受根治性手术、接受化疗、更高比例的1级疾病、淋巴结阴性和更低的淋巴血管侵袭率(P < 0.001)。nomogram包括年龄、性别和手术切缘。结论:通过有效的患者选择和适当的护理,一部分PM患者可以成为长期幸存者。本研究强调了影响LTS的关键因素,为个性化治疗策略和提高预后铺平了道路。需要进一步的研究来改善患者选择,并确保可能成为LTS的患者得到充分的护理。
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引用次数: 0
The Influence of Differences in Surgical Access on the Development of Early Asymptomatic DVT After Inguinal Hernia Surgery. 手术通路差异对腹股沟疝术后早期无症状深静脉血栓形成的影响。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2026-01-01 Epub Date: 2025-06-19 DOI: 10.1177/00031348251353802
Nanxiang Zhang, Chao Zhang, Yaqiang Shu, Muyu Fu, Jiayue Li, Chenggang Huang, Xiaohua Lei

ObjectiveThis study aimed to examine the effect of surgical approach on the incidence of early asymptomatic deep vein thrombosis (DVT) following inguinal hernia surgery and to evaluate additional factors influencing postoperative asymptomatic DVT formation. The study seeks to provide guidance and support for the diagnosis and treatment of early postoperative asymptomatic DVT.MethodsThe present study is a retrospective study. Our study finally included 565 patients with inguinal hernia divided into laparoscopic and open surgery groups. Bilateral lower extremity venous Doppler ultrasonography was performed on the second postoperative day to document the occurrence of asymptomatic DVT in the early postoperative period. A 1:1 matching was performed using propensity score matching (PSM). Independent factors affecting early postoperative asymptomatic DVT were determined using multivariate binary logistic regression analysis.ResultsThere were 565 patients, in which 317 underwent laparoscopic surgery and 248 underwent open surgery. Propensity score matching yielded 102 matched pairs for further analysis. In multivariate analysis, bilateral hernias (OR = 50.546, 95% CI 2.277-1122.159, P = 0.013) and total length of stay (OR = 1.807, 95% CI 1.239-2.634, P = 0.002) were identified as independent risk factors for early postoperative asymptomatic DVT, whereas preoperative length of stay (OR = 0.341, 95% CI 0.162-0.719, P = 0.005) and operation time (OR = 0.965, 95% CI 0.936-0.995, P = 0.021) served as protective factors. There was no significant impact of laparoscopic or open surgery on the incidence of early postoperative asymptomatic DVT (OR = 1.808, 95% CI: 0.288-11.361, P = 0.528).ConclusionThe choice of laparoscopic vs open inguinal hernia repair did not significantly affect the incidence of early postoperative asymptomatic DVT. In this study, effective perioperative management, whether through preoperative admission to manage significant comorbidities or a reduced overall length of stay, lowered the incidence of early postoperative asymptomatic DVT, particularly in patients with bilateral inguinal hernias.

目的探讨手术入路对腹股沟疝术后早期无症状深静脉血栓(DVT)发生率的影响,并探讨影响术后无症状深静脉血栓形成的其他因素。本研究旨在为术后早期无症状深静脉血栓的诊断和治疗提供指导和支持。方法本研究为回顾性研究。我们的研究最终纳入565例腹股沟疝患者,分为腹腔镜组和开放手术组。术后第二天行双侧下肢静脉多普勒超声检查,记录术后早期无症状深静脉血栓的发生情况。采用倾向评分匹配(PSM)进行1:1匹配。采用多元二元logistic回归分析确定影响术后早期无症状深静脉血栓形成的独立因素。结果565例患者中腹腔镜手术317例,开腹手术248例。倾向评分匹配得到102对配对,供进一步分析。在多因素分析中,双侧疝(OR = 50.546, 95% CI 2.277 ~ 1122.159, P = 0.013)和总住院时间(OR = 1.807, 95% CI 1.239 ~ 2.634, P = 0.002)是术后早期无症状DVT的独立危险因素,术前住院时间(OR = 0.341, 95% CI 0.162 ~ 0.719, P = 0.005)和手术时间(OR = 0.965, 95% CI 0.936 ~ 0.995, P = 0.021)是术后早期无症状DVT的保护因素。腹腔镜或开放手术对术后早期无症状DVT发生率无显著影响(or = 1.808, 95% CI: 0.288 ~ 11.361, P = 0.528)。结论腹腔镜与开放式腹股沟疝修补术的选择对术后早期无症状深静脉血栓的发生率无显著影响。在本研究中,有效的围手术期管理,无论是通过术前入院处理显著合并症还是减少总住院时间,都降低了术后早期无症状DVT的发生率,尤其是双侧腹股沟疝患者。
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引用次数: 0
Identifying the Surgical to Nonsurgical Care Transition for Trauma Patients: Time to Redesign Trauma Workflow. 确定创伤患者从手术到非手术护理的过渡:重新设计创伤工作流程的时间。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2026-01-01 Epub Date: 2025-06-27 DOI: 10.1177/00031348251353804
Ursula Adams, William Yu Luo, Kevin Chen Wang, Didong Li, Pascal Osita Udekwu, Anthony Charles

IntroductionThe burden of traumatic injury in the United States continues to outpace the rate of trauma surgeons entering practice within a larger surgical workforce crisis. Furthermore, a trauma length of stay can be prolonged by many nonsurgical factors, including nonsurgical procedures, medical comorbidities, and socioeconomic barriers to discharge. We hypothesize that using a time-series analysis to predict the likelihood of surgeon-directed procedures can aid trauma centers in redesigning the trauma workflow and more efficiently deploying surgical resources.MethodsWe performed a single-institution, retrospective cohort study, including adult (≥18 years) trauma patients admitted to a level 1 trauma center between 2018 and 2022. Hospital billing and charge data were collected to determine procedure-level data. Procedures were classified as surgeon-directed or non-surgeon-directed. Probabilities were generated based on the likelihood of patients remaining hospitalized and requiring a surgeon-directed procedure.Results7382 patients underwent 3138 unique procedures. Of these patients, 6095 (82.6%) had at least one surgeon-directed procedure; 1287 (17.4%) had no surgeon-directed procedure. The length of stay was marginally longer in patients who underwent surgeon-directed procedures. For all patients, the likelihood of needing a surgeon-directed procedure declines each day of admission but stabilizes after day 5.ConclusionsIn our population, the surgical to nonsurgical transition during a trauma admission occurs after day 5. However, this may vary across institutions and not apply to patients requiring complex surgical intervention. Our methods can be used to structure and optimize the deployment of surgical resources only during the period with the highest surgical need.

在美国,创伤性损伤的负担继续超过创伤外科医生进入实践的速度,这是一个更大的外科劳动力危机。此外,创伤住院时间可因许多非手术因素而延长,包括非手术治疗、医疗合并症和出院的社会经济障碍。我们假设使用时间序列分析来预测外科指导手术的可能性可以帮助创伤中心重新设计创伤工作流程并更有效地部署手术资源。方法:我们进行了一项单机构、回顾性队列研究,纳入了2018年至2022年在一级创伤中心住院的成人(≥18岁)创伤患者。收集医院账单和收费数据以确定程序级数据。手术分为外科医生指导和非外科医生指导。概率是根据患者继续住院并需要外科医生指导手术的可能性产生的。结果7382例患者接受了3138例独特手术。在这些患者中,6095例(82.6%)至少进行了一次外科医生指导的手术;1287例(17.4%)未接受外科指导手术。接受外科指导手术的患者住院时间稍长。对于所有患者来说,需要外科医生指导手术的可能性每天都在下降,但在第5天后稳定下来。结论在我们的人群中,创伤入院时手术向非手术过渡发生在第5天之后。然而,这可能因机构而异,不适用于需要复杂手术干预的患者。我们的方法可用于在手术需求最高的时期组织和优化手术资源的部署。
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引用次数: 0
Is There Common Ground? A Comparison of Laparoscopic Common Bile Duct Exploration by Acute Care Surgery and Minimally Invasive Surgery Fellowship Trained Surgeons. 有共同点吗?急诊外科与微创外科实习医师腹腔镜胆总管探查的比较。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2026-01-01 Epub Date: 2025-07-03 DOI: 10.1177/00031348251358445
Maggie E Bosley, Elizabeth C Wood, Lucas P Neff, Juhi Saxena, Gabriel E Cambronero, Gloria D Sanin, Shan L Kalmeta, Vahagn C Nikolian, Ranjan Sudan

BackgroundLaparoscopic common bile duct exploration (LCBDE) is underutilized by surgeons to treat choledocholithiasis. We hypothesized that fellowship training in acute care surgery (ACS) vs minimally invasive surgery (MIS) results in different LCBDE practices and perceptions, thus producing unique barriers to implementation.MethodsA survey was distributed by email to members of Society of American Gastrointestinal and Endoscopic Surgeons and the American Association for the Surgery of Trauma to assess surgeon demographics, surgeon-specific perceptions, practice patterns, and barriers to LCBDE utilization. Categorical data were compared with Pearson's chi-square, and continuous parametric data were compared with a t test.Results543 US surgeons who perform laparoscopic cholecystectomy completed the survey. Of all, 124 survey respondents were ACS trained and 175 were MIS trained. Similar proportions of MIS and ACS surgeons prefer to manage choledocholithiasis with LCBDE (28% vs 27%, P = 0.79). The most utilized LCBDE technique was choledochoscopy (71% vs 69%, P = 0.17). MIS surgeons more frequently perform intraoperative cholangiogram (IOC) compared to ACS surgeons (P = 0.02). A third of MIS surgeons felt that LCBDE is too time consuming to be of value, vs 25% of ACS surgeons (P = 0.37). When asked if LCBDE is difficult to master, 56% of MIS surgeons agreed compared to 32% of ACS surgeons (P < 0.01).DiscussionBoth MIS and ACS surgeons utilize LCBDE infrequently despite responding that choledocholithiasis should be managed by surgeons. Compared to MIS, fewer ACS surgeons consider time to perform LCBDE and difficulty as barriers. Understanding these barriers can influence education and efforts toward increasing adoption in both groups.

背景腹腔镜胆总管探查术(LCBDE)在外科医生治疗胆总管结石中的应用不足。我们假设急症外科(ACS)与微创外科(MIS)的奖学金培训导致不同的LCBDE实践和认知,从而产生独特的实施障碍。方法通过电子邮件向美国胃肠和内窥镜外科医生协会和美国创伤外科协会的成员分发一项调查,以评估外科医生的人口统计学特征、外科医生的特定观念、实践模式和使用LCBDE的障碍。分类资料采用Pearson卡方比较,连续参数资料采用t检验比较。结果543名实施腹腔镜胆囊切除术的美国外科医生完成了调查。其中124名受访者接受过ACS培训,175名接受过管理信息系统培训。相似比例的MIS和ACS外科医生更倾向于用LCBDE治疗胆总管结石(28% vs 27%, P = 0.79)。使用最多的LCBDE技术是胆道镜检查(71% vs 69%, P = 0.17)。与ACS外科医生相比,MIS外科医生更频繁地进行术中胆管造影(IOC) (P = 0.02)。三分之一的MIS外科医生认为LCBDE太耗时而没有价值,而ACS外科医生的这一比例为25% (P = 0.37)。当被问及LCBDE是否难以掌握时,56%的MIS外科医生同意,而32%的ACS外科医生同意(P < 0.01)。MIS和ACS的外科医生都很少使用LCBDE,尽管他们认为胆总管结石应该由外科医生来治疗。与MIS相比,很少有ACS外科医生认为进行LCBDE的时间和难度是障碍。了解这些障碍可以影响教育和在这两个群体中增加采用的努力。
{"title":"Is There Common Ground? A Comparison of Laparoscopic Common Bile Duct Exploration by Acute Care Surgery and Minimally Invasive Surgery Fellowship Trained Surgeons.","authors":"Maggie E Bosley, Elizabeth C Wood, Lucas P Neff, Juhi Saxena, Gabriel E Cambronero, Gloria D Sanin, Shan L Kalmeta, Vahagn C Nikolian, Ranjan Sudan","doi":"10.1177/00031348251358445","DOIUrl":"10.1177/00031348251358445","url":null,"abstract":"<p><p>BackgroundLaparoscopic common bile duct exploration (LCBDE) is underutilized by surgeons to treat choledocholithiasis. We hypothesized that fellowship training in acute care surgery (ACS) vs minimally invasive surgery (MIS) results in different LCBDE practices and perceptions, thus producing unique barriers to implementation.MethodsA survey was distributed by email to members of Society of American Gastrointestinal and Endoscopic Surgeons and the American Association for the Surgery of Trauma to assess surgeon demographics, surgeon-specific perceptions, practice patterns, and barriers to LCBDE utilization. Categorical data were compared with Pearson's chi-square, and continuous parametric data were compared with a <i>t</i> test.Results543 US surgeons who perform laparoscopic cholecystectomy completed the survey. Of all, 124 survey respondents were ACS trained and 175 were MIS trained. Similar proportions of MIS and ACS surgeons prefer to manage choledocholithiasis with LCBDE (28% vs 27%, <i>P</i> = 0.79). The most utilized LCBDE technique was choledochoscopy (71% vs 69%, <i>P</i> = 0.17). MIS surgeons more frequently perform intraoperative cholangiogram (IOC) compared to ACS surgeons (<i>P</i> = 0.02). A third of MIS surgeons felt that LCBDE is too time consuming to be of value, vs 25% of ACS surgeons (<i>P</i> = 0.37). When asked if LCBDE is difficult to master, 56% of MIS surgeons agreed compared to 32% of ACS surgeons (<i>P</i> < 0.01).DiscussionBoth MIS and ACS surgeons utilize LCBDE infrequently despite responding that choledocholithiasis should be managed by surgeons. Compared to MIS, fewer ACS surgeons consider time to perform LCBDE and difficulty as barriers. Understanding these barriers can influence education and efforts toward increasing adoption in both groups.</p>","PeriodicalId":7782,"journal":{"name":"American Surgeon","volume":" ","pages":"140-145"},"PeriodicalIF":0.9,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic Anti-Reflux Surgery as Primary Treatment for IEM due to GERD. 腹腔镜抗反流手术作为胃食管反流所致IEM的主要治疗方法。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-12-20 DOI: 10.1177/00031348251409739
Yassmin K Hegazy, Mary M Evans, Grace H Howell, Jeremy T Morgan, Andrew B Seals, Chungeun Lee, Eldrin L Bhanat, Venkata N Seerapu, Jacob R Moremen

Ineffective esophageal motility (IEM) related to gastroesophageal reflux disease (GERD) presents unique treatment challenges. Our study evaluates symptom outcomes in patients with IEM due to GERD undergoing laparoscopic anti-reflux surgery (LARS) to determine the incidence of subjective symptomatic improvement and evidence of worsened dysphagia. Following institutional review board (IRB) approval, we retrospectively evaluated patients who underwent LARS for GERD who demonstrated IEM on pre-operative high-resolution manometry (HRM) based on the Chicago 3 classification and evaluated symptom resolution at post-operative visits. 29 patients with IEM underwent LARS with the most frequent presenting complaints being regurgitation (24/29, 83%) and dysphagia (21/29, 72%). In patients presenting with dysphagia, 70.8% reported resolution at the first post-operative visit. The mean rate of resolution of dysphagia and regurgitation by the last follow-up was 78% and 85.7%, respectively. Laparoscopic anti-reflux surgery for IEM due to GERD resulted in subjective improvement in presenting symptoms including dysphagia and regurgitation with minimal complications and no generation of new post-operative dysphagia.

与胃食管反流病(GERD)相关的食管动力低下(IEM)提出了独特的治疗挑战。我们的研究评估了接受腹腔镜抗反流手术(LARS)的胃食管反流导致IEM患者的症状结局,以确定主观症状改善的发生率和吞咽困难恶化的证据。在机构审查委员会(IRB)批准后,我们回顾性评估了接受LARS治疗的GERD患者,这些患者术前高分辨率测压(HRM)显示IEM,基于芝加哥3分类,并在术后就诊时评估症状缓解情况。29例IEM患者行LARS,最常见的主诉是反流(24/29,83%)和吞咽困难(21/29,72%)。在出现吞咽困难的患者中,70.8%的患者在术后第一次就诊时报告了缓解。最后一次随访时,吞咽困难和反流的平均缓解率分别为78%和85.7%。腹腔镜下抗反流手术治疗因胃食管反流引起的IEM,主观上改善了吞咽困难和反流等症状,并发症最少,术后没有产生新的吞咽困难。
{"title":"Laparoscopic Anti-Reflux Surgery as Primary Treatment for IEM due to GERD.","authors":"Yassmin K Hegazy, Mary M Evans, Grace H Howell, Jeremy T Morgan, Andrew B Seals, Chungeun Lee, Eldrin L Bhanat, Venkata N Seerapu, Jacob R Moremen","doi":"10.1177/00031348251409739","DOIUrl":"https://doi.org/10.1177/00031348251409739","url":null,"abstract":"<p><p>Ineffective esophageal motility (IEM) related to gastroesophageal reflux disease (GERD) presents unique treatment challenges. Our study evaluates symptom outcomes in patients with IEM due to GERD undergoing laparoscopic anti-reflux surgery (LARS) to determine the incidence of subjective symptomatic improvement and evidence of worsened dysphagia. Following institutional review board (IRB) approval, we retrospectively evaluated patients who underwent LARS for GERD who demonstrated IEM on pre-operative high-resolution manometry (HRM) based on the Chicago 3 classification and evaluated symptom resolution at post-operative visits. 29 patients with IEM underwent LARS with the most frequent presenting complaints being regurgitation (24/29, 83%) and dysphagia (21/29, 72%). In patients presenting with dysphagia, 70.8% reported resolution at the first post-operative visit. The mean rate of resolution of dysphagia and regurgitation by the last follow-up was 78% and 85.7%, respectively. Laparoscopic anti-reflux surgery for IEM due to GERD resulted in subjective improvement in presenting symptoms including dysphagia and regurgitation with minimal complications and no generation of new post-operative dysphagia.</p>","PeriodicalId":7782,"journal":{"name":"American Surgeon","volume":" ","pages":"31348251409739"},"PeriodicalIF":0.9,"publicationDate":"2025-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospect: A Conversation With Allen Oldfather Whipple. 回顾:与Allen Oldfather Whipple的对话。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-12-20 DOI: 10.1177/00031348251409735
Emmanuel E Zervos

Through new and astonishing capabilities of artificial intelligence, the editors of The American Surgeon have been able to step back in time and conduct a virtual interview with the most eponymous surgeon in history: Allen Oldfather Whipple. We caught up with Dr. Whipple on September 2nd, 1946, shortly after completing the final operation of his surgical career; not surprisingly, a pancreaticoduodenectomy.

通过人工智能令人惊叹的新功能,《美国外科医生》的编辑们能够回到过去,对历史上最著名的外科医生艾伦·奥德菲德·惠普尔进行了一次虚拟采访。1946年9月2日,我们采访了惠普尔医生,当时他刚刚完成了外科生涯的最后一次手术;毫不奇怪,胰十二指肠切除术。
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引用次数: 0
Comparison of Wound Infusion Catheter Versus Epidural Catheter for Analgesia After Midline Incision for Major Abdominal Surgery: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. 腹部大手术中线切口后伤口输注导管与硬膜外导管镇痛的比较:随机对照试验的系统回顾和荟萃分析。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-12-20 DOI: 10.1177/00031348251409737
Mohamed Albendary, Hussam Khougali Mohamed, Salma Saeed Mohammed, Dina Nada, Asaad Yassin Mohamedahmed, Mohamed Refaie, Mohamed Elaraby, Ali Yasen Mohamedahmed

BackgroundTo evaluate comparative outcomes of wound infusion catheter (WC) vs epidural analgesia (EP) for analgesia following midline laparotomy for abdominal surgery.MethodsA systematic search of PubMed, Cochrane Library, and Scopus was conducted, and all randomised controlled trials (RCTs) comparing WC vs EP for analgesia after midline laparotomy were included. Overall pain scores, total morphine consumption, respiratory depression, catheter-related complications, time of first bowel movement, and length of hospital stay (LOS) were set as outcome parameters for the meta-analysis. Subgroups of catheter positions, including preperitoneal, rectus sheath and transversus abdominis plane block as deep WC and subcutaneous WC, were examined for pain scores superiority.ResultsTwelve RCTs were pooled in a meta-analysis, involving a total of 778 patients who received WC (n = 390) or EP (n = 388). There was no significant difference in pain scores at rest and movement between WC and EP groups at 24 hours [P = .85 and P = .30, respectively] and 48 hours [P = .33 and P = .06, respectively]. However, subgroup analysis, excluding subcutaneous catheters, showed favourable pain scores on movement at 48 hours of use (mean difference [MD] -0.97, P = .03). The LOS was notably shorter in the WC group [MD, -0.50; P < .001]. There were no significant differences between both groups in cumulative morphine consumption [P = .33], return of bowel function [P = .13], respiratory depression [P = .43], or catheter-related complications [P = .16].ConclusionWC generally provides a comparable postoperative analgesia to EP; however, it is associated with shorter LOS and a slight superiority of analgesia of deep catheters. Comparing different types of nerve blocks and positions of catheters in future research may optimise the use of WC.

研究背景:比较切口输注导管(WC)与硬膜外镇痛(EP)在腹部手术中线剖腹术后镇痛中的效果。方法系统检索PubMed、Cochrane Library和Scopus数据库,纳入所有比较WC与EP在剖腹切开术后镇痛效果的随机对照试验(RCTs)。总疼痛评分、吗啡总用量、呼吸抑制、导管相关并发症、首次排便时间和住院时间(LOS)被设置为meta分析的结果参数。不同导管位置的亚组,包括腹膜前、直肌鞘和横腹平面阻滞作为深度WC和皮下WC,检查疼痛评分的优势。结果12项随机对照试验纳入荟萃分析,共涉及778例接受WC (n = 390)或EP (n = 388)的患者。在24小时[P = 0.85和P = 0.30]和48小时[P = 0.33和P = 0.06]时,WC组和EP组休息和运动时疼痛评分无显著差异。然而,亚组分析(不包括皮下导管)显示,使用48小时时运动疼痛评分良好(平均差异[MD] -0.97, P = .03)。WC组的LOS明显较短[MD, -0.50;P < 0.001]。两组在吗啡累积用量[P = 0.33]、肠功能恢复[P = 0.13]、呼吸抑制[P = 0.43]、导管相关并发症[P = 0.16]方面无显著差异。结论wc与EP具有相当的术后镇痛效果;然而,它与较短的LOS和深置管镇痛的轻微优势有关。在未来的研究中,比较不同类型的神经阻滞和导管的位置可以优化WC的使用。
{"title":"Comparison of Wound Infusion Catheter Versus Epidural Catheter for Analgesia After Midline Incision for Major Abdominal Surgery: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.","authors":"Mohamed Albendary, Hussam Khougali Mohamed, Salma Saeed Mohammed, Dina Nada, Asaad Yassin Mohamedahmed, Mohamed Refaie, Mohamed Elaraby, Ali Yasen Mohamedahmed","doi":"10.1177/00031348251409737","DOIUrl":"https://doi.org/10.1177/00031348251409737","url":null,"abstract":"<p><p>BackgroundTo evaluate comparative outcomes of wound infusion catheter (WC) vs epidural analgesia (EP) for analgesia following midline laparotomy for abdominal surgery.MethodsA systematic search of PubMed, Cochrane Library, and Scopus was conducted, and all randomised controlled trials (RCTs) comparing WC vs EP for analgesia after midline laparotomy were included. Overall pain scores, total morphine consumption, respiratory depression, catheter-related complications, time of first bowel movement, and length of hospital stay (LOS) were set as outcome parameters for the meta-analysis. Subgroups of catheter positions, including preperitoneal, rectus sheath and transversus abdominis plane block as deep WC and subcutaneous WC, were examined for pain scores superiority.ResultsTwelve RCTs were pooled in a meta-analysis, involving a total of 778 patients who received WC (n = 390) or EP (n = 388). There was no significant difference in pain scores at rest and movement between WC and EP groups at 24 hours [<i>P</i> = .85 and <i>P</i> = .30, respectively] and 48 hours [<i>P</i> = .33 and <i>P</i> = .06, respectively]. However, subgroup analysis, excluding subcutaneous catheters, showed favourable pain scores on movement at 48 hours of use (mean difference [MD] -0.97, <i>P</i> = .03). The LOS was notably shorter in the WC group [MD, -0.50; <i>P</i> < .001]. There were no significant differences between both groups in cumulative morphine consumption [<i>P</i> = .33], return of bowel function [<i>P</i> = .13], respiratory depression [<i>P</i> = .43], or catheter-related complications [<i>P</i> = .16].ConclusionWC generally provides a comparable postoperative analgesia to EP; however, it is associated with shorter LOS and a slight superiority of analgesia of deep catheters. Comparing different types of nerve blocks and positions of catheters in future research may optimise the use of WC.</p>","PeriodicalId":7782,"journal":{"name":"American Surgeon","volume":" ","pages":"31348251409737"},"PeriodicalIF":0.9,"publicationDate":"2025-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex-Based Differences in Surgical Stabilization Outcomes for Rib Fractures in Blunt Trauma Patients. 钝性创伤患者肋骨骨折手术稳定结果的性别差异。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-12-18 DOI: 10.1177/00031348251407349
Negaar Aryan, Sebastian Dominik Schubl, Jeffry Nahmias, Matthew Dolich, Michael Lekawa, Jiabao Nie, Areg Grigorian

Sex-based differences in rib fracture presentation and recovery may influence surgical stabilization of rib fractures (SSRF) outcomes. Greater chest wall muscle mass in males may necessitate higher-energy trauma to cause rib fractures, increasing the risk of respiratory complications.

Objective: We compared the rates of SSRF in male and female blunt trauma patients (BTPs) with rib fractures, hypothesizing that males would undergo SSRF at a higher rate and experience increased respiratory complications following SSRF.

Methods: TQIP (2017-2022) was queried for adult BTPs with multiple rib fractures and/or flail segment. Male SSRF BTPs were compared to female SSRF BTPs. Multivariable logistic regression analysis was performed to determine if sex was associated with an increased risk of respiratory complications [unplanned intubation, acute respiratory distress syndrome (ARDS), and ventilator-associated pneumonia (VAP)].

Results: The rate of SSRF in males was 3.1% and 2.3% in females (P < .001). From 20 487 SSRF patients, 15 086 (74%) were male. Both groups had similar median injury severity scores (ISS) of 17; however, males had higher rates of severe thoracic injury (34.7% vs 31.1%, P < .001). Males had higher rates of overall respiratory complications (13.0% vs 10.3%) including ARDS (1.9% vs 1.3%), VAP (3.9% vs 2.4%), and unplanned intubation (7.8% vs 6.8%) (all P < .05). On multivariable analysis, males had an increased risk of respiratory complications (OR 1.37, CI 1.24-1.52, P < .001) and mortality (OR 1.33, CI 1.07-1.65, P = .01).

Conclusion: Despite comparable ISS, males more frequently underwent SSRF and had increased risk of respiratory complications and mortality post-operatively. These disparities may reflect underlying anatomical/physiological factors.

肋骨骨折表现和恢复的性别差异可能影响肋骨骨折的手术稳定(SSRF)结果。男性胸壁肌肉量大可能需要高能创伤导致肋骨骨折,增加呼吸系统并发症的风险。目的:我们比较了男性和女性钝性创伤患者(BTPs)肋骨骨折的SSRF发生率,假设男性接受SSRF的发生率更高,并且SSRF后呼吸系统并发症增加。方法:对多发肋骨骨折和/或连枷节段的成人btp患者进行TQIP(2017-2022)查询。将男性SSRF btp与女性SSRF btp比较。进行多变量logistic回归分析以确定性别是否与呼吸系统并发症(意外插管、急性呼吸窘迫综合征(ARDS)和呼吸机相关性肺炎(VAP))的风险增加相关。结果:SSRF阳性率男性为3.1%,女性为2.3% (P < 0.001)。在20487例SSRF患者中,15086例(74%)为男性。两组的中位损伤严重程度评分(ISS)相似,均为17分;而男性的严重胸外伤发生率较高(34.7% vs 31.1%, P < 0.001)。男性总体呼吸系统并发症发生率较高(13.0%比10.3%),包括ARDS(1.9%比1.3%)、VAP(3.9%比2.4%)和计划外插管(7.8%比6.8%)(均P < 0.05)。在多变量分析中,男性呼吸系统并发症(OR 1.37, CI 1.24-1.52, P < 0.001)和死亡率(OR 1.33, CI 1.07-1.65, P = 0.01)的风险增加。结论:尽管有类似的ISS,但男性更频繁地接受SSRF,并且术后呼吸并发症和死亡率的风险增加。这些差异可能反映了潜在的解剖/生理因素。
{"title":"Sex-Based Differences in Surgical Stabilization Outcomes for Rib Fractures in Blunt Trauma Patients.","authors":"Negaar Aryan, Sebastian Dominik Schubl, Jeffry Nahmias, Matthew Dolich, Michael Lekawa, Jiabao Nie, Areg Grigorian","doi":"10.1177/00031348251407349","DOIUrl":"https://doi.org/10.1177/00031348251407349","url":null,"abstract":"<p><p>Sex-based differences in rib fracture presentation and recovery may influence surgical stabilization of rib fractures (SSRF) outcomes. Greater chest wall muscle mass in males may necessitate higher-energy trauma to cause rib fractures, increasing the risk of respiratory complications.</p><p><strong>Objective: </strong>We compared the rates of SSRF in male and female blunt trauma patients (BTPs) with rib fractures, hypothesizing that males would undergo SSRF at a higher rate and experience increased respiratory complications following SSRF.</p><p><strong>Methods: </strong>TQIP (2017-2022) was queried for adult BTPs with multiple rib fractures and/or flail segment. Male SSRF BTPs were compared to female SSRF BTPs. Multivariable logistic regression analysis was performed to determine if sex was associated with an increased risk of respiratory complications [unplanned intubation, acute respiratory distress syndrome (ARDS), and ventilator-associated pneumonia (VAP)].</p><p><strong>Results: </strong>The rate of SSRF in males was 3.1% and 2.3% in females (<i>P</i> < .001). From 20 487 SSRF patients, 15 086 (74%) were male. Both groups had similar median injury severity scores (ISS) of 17; however, males had higher rates of severe thoracic injury (34.7% vs 31.1%, <i>P</i> < .001). Males had higher rates of overall respiratory complications (13.0% vs 10.3%) including ARDS (1.9% vs 1.3%), VAP (3.9% vs 2.4%), and unplanned intubation (7.8% vs 6.8%) (all <i>P</i> < .05). On multivariable analysis, males had an increased risk of respiratory complications (OR 1.37, CI 1.24-1.52, <i>P</i> < .001) and mortality (OR 1.33, CI 1.07-1.65, <i>P</i> = .01).</p><p><strong>Conclusion: </strong>Despite comparable ISS, males more frequently underwent SSRF and had increased risk of respiratory complications and mortality post-operatively. These disparities may reflect underlying anatomical/physiological factors.</p>","PeriodicalId":7782,"journal":{"name":"American Surgeon","volume":" ","pages":"31348251407349"},"PeriodicalIF":0.9,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145773446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Bariatric Surgery in Modulating Fetuin-A and Metabolic Outcomes: A Systematic Review and Meta-Analysis. 减肥手术在调节胎儿素A和代谢结果中的作用:系统回顾和荟萃分析。
IF 0.9 4区 医学 Q3 SURGERY Pub Date : 2025-12-11 DOI: 10.1177/00031348251407347
Chenglou Zhu, Wenhan Liu

ObjectiveTo evaluate the impact of metabolic and bariatric surgery (MBS) on plasma Fetuin-A expression, body mass index (BMI), and glucose levels in patients with obesity.MethodsA systematic literature search was performed in PubMed, Cochrane Library, Web of science, and Embase following the PRISMA guidelines. A total of 5 studies (n = 298 participants) were included, reporting pre- and post-surgery plasma Fetuin-A levels, BMI, and glucose levels. Two independent reviewers extracted data, with discrepancies resolved by a third reviewer. Pooled standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated for each outcome. Heterogeneity was assessed using the I2 statistic.ResultsThe pooled results revealed a significant reduction in plasma Fetuin-A levels post-surgery (SMD = -0.43, 95% CI = -0.73 to -0.14, P < .05, I2 = 60.7%). BMI also decreased significantly following MBS (SMD = -1.74, 95% CI = -2.28 to -1.19, P < .05, I2 = 84.2%). Additionally, glucose levels showed a marked reduction post-surgery (SMD = -0.94, 95% CI = -1.12 to -0.76, P < .05, I2 = 16.2%).ConclusionMBS is associated with significant reductions in plasma Fetuin-A levels, BMI, and glucose levels. These findings indicate that changes in Fetuin-A may accompany the metabolic improvements observed after MBS, although causal mechanisms cannot be established from the available evidence.

目的探讨代谢与减肥手术(MBS)对肥胖患者血浆Fetuin-A表达、体重指数(BMI)及血糖水平的影响。方法按照PRISMA指南,在PubMed、Cochrane Library、Web of science和Embase中进行系统文献检索。共纳入5项研究(n = 298名参与者),报告了术前和术后血浆Fetuin-A水平、BMI和血糖水平。两名独立审稿人提取数据,差异由第三名审稿人解决。计算每个结果的合并标准化平均差异(SMD)和95%置信区间(CI)。采用I2统计量评估异质性。结果术后血浆Fetuin-A水平显著降低(SMD = -0.43, 95% CI = -0.73 ~ -0.14, P < 0.05, I2 = 60.7%)。MBS后BMI也显著降低(SMD = -1.74, 95% CI = -2.28 ~ -1.19, P < 0.05, I2 = 84.2%)。此外,术后血糖水平明显降低(SMD = -0.94, 95% CI = -1.12 ~ -0.76, P < 0.05, I2 = 16.2%)。结论:mbs可显著降低血浆胎儿素a水平、BMI和血糖水平。这些发现表明,尽管现有证据无法建立因果机制,但MBS后观察到的代谢改善可能伴随着Fetuin-A的变化。
{"title":"Role of Bariatric Surgery in Modulating Fetuin-A and Metabolic Outcomes: A Systematic Review and Meta-Analysis.","authors":"Chenglou Zhu, Wenhan Liu","doi":"10.1177/00031348251407347","DOIUrl":"https://doi.org/10.1177/00031348251407347","url":null,"abstract":"<p><p>ObjectiveTo evaluate the impact of metabolic and bariatric surgery (MBS) on plasma Fetuin-A expression, body mass index (BMI), and glucose levels in patients with obesity.MethodsA systematic literature search was performed in PubMed, Cochrane Library, Web of science, and Embase following the PRISMA guidelines. A total of 5 studies (n = 298 participants) were included, reporting pre- and post-surgery plasma Fetuin-A levels, BMI, and glucose levels. Two independent reviewers extracted data, with discrepancies resolved by a third reviewer. Pooled standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated for each outcome. Heterogeneity was assessed using the I<sup>2</sup> statistic.ResultsThe pooled results revealed a significant reduction in plasma Fetuin-A levels post-surgery (SMD = -0.43, 95% CI = -0.73 to -0.14, <i>P</i> < .05, I<sup>2</sup> = 60.7%). BMI also decreased significantly following MBS (SMD = -1.74, 95% CI = -2.28 to -1.19, <i>P</i> < .05, I<sup>2</sup> = 84.2%). Additionally, glucose levels showed a marked reduction post-surgery (SMD = -0.94, 95% CI = -1.12 to -0.76, <i>P</i> < .05, I<sup>2</sup> = 16.2%).ConclusionMBS is associated with significant reductions in plasma Fetuin-A levels, BMI, and glucose levels. These findings indicate that changes in Fetuin-A may accompany the metabolic improvements observed after MBS, although causal mechanisms cannot be established from the available evidence.</p>","PeriodicalId":7782,"journal":{"name":"American Surgeon","volume":" ","pages":"31348251407347"},"PeriodicalIF":0.9,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145740702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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American Surgeon
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