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Double invasion: an unprecedented case of metastases from two distinct primary sites coexisting in a single cutaneous lesion 双重侵袭：一个前所未有的病例转移从两个不同的原发部位共存于单一皮肤病变
IF 3.6 4区 医学 Q2 DERMATOLOGY
Anais brasileiros de dermatologia
Pub Date : 2025-08-18 DOI: 10.1016/j.abd.2025.501195
Matheus Alves Pacheco , Amanda Amaro Pereira , Leonardo Simas Abi Saab , Rúbia Tabata Rigatti , Oscar Cardoso Dimatos , Athos Paulo Santos Martini
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引用次数: 0
Successful treatment of refractory eosinophilic annular erythema with tofacitinib 托法替尼成功治疗难治性嗜酸性环状红斑
IF 3.6 4区 医学 Q2 DERMATOLOGY
Anais brasileiros de dermatologia
Pub Date : 2025-08-18 DOI: 10.1016/j.abd.2025.501194
Ying-Luo Niu, Hai-Yang He, Sheng Fang
{"title":"Successful treatment of refractory eosinophilic annular erythema with tofacitinib","authors":"Ying-Luo Niu, Hai-Yang He, Sheng Fang","doi":"10.1016/j.abd.2025.501194","DOIUrl":"10.1016/j.abd.2025.501194","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501194"},"PeriodicalIF":3.6,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144860360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multinucleated cell angiohistiocytoma: independent entity or variant of dermatofibroma? Rosettes and shiny white lines as new dermoscopic findings 多核细胞血管组织细胞瘤：皮肤纤维瘤的独立实体还是变体？玫瑰和闪亮的白线是新的皮肤镜发现
IF 3.6 4区 医学 Q2 DERMATOLOGY
Anais brasileiros de dermatologia
Pub Date : 2025-08-15 DOI: 10.1016/j.abd.2025.501183
Sara Becerril-Andrés , Eduardo de la Rosa-Fernández , Jesús del Pozo-Losada
{"title":"Multinucleated cell angiohistiocytoma: independent entity or variant of dermatofibroma? Rosettes and shiny white lines as new dermoscopic findings","authors":"Sara Becerril-Andrés , Eduardo de la Rosa-Fernández , Jesús del Pozo-Losada","doi":"10.1016/j.abd.2025.501183","DOIUrl":"10.1016/j.abd.2025.501183","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501183"},"PeriodicalIF":3.6,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144842354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paradoxical morphea-like reaction after initiation of dupilumab for nodular prurigo 杜匹单抗治疗结节性痒疹后的反常吗啡样反应
IF 3.6 4区 医学 Q2 DERMATOLOGY
Anais brasileiros de dermatologia
Pub Date : 2025-08-15 DOI: 10.1016/j.abd.2025.501193
José González Fernández , Mariano Ara Martín , Sergio García González , Sara Pilar Martínez Cisneros , Mar García García , Sonia de la Fuente Meira
{"title":"Paradoxical morphea-like reaction after initiation of dupilumab for nodular prurigo","authors":"José González Fernández , Mariano Ara Martín , Sergio García González , Sara Pilar Martínez Cisneros , Mar García García , Sonia de la Fuente Meira","doi":"10.1016/j.abd.2025.501193","DOIUrl":"10.1016/j.abd.2025.501193","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501193"},"PeriodicalIF":3.6,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144842357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kaposi’s sarcoma overlying Mpox scars – Case report 覆盖m痘疤痕的卡波西肉瘤1例报告
IF 3.6 4区 医学 Q2 DERMATOLOGY
Anais brasileiros de dermatologia
Pub Date : 2025-08-15 DOI: 10.1016/j.abd.2025.501186
José Paulo Ribeiro Júnior , Thaís Barros Felippe Jabour , Liana Franco de Sousa Barros , Juliana Carlos Gonçalves Rego
{"title":"Kaposi’s sarcoma overlying Mpox scars – Case report","authors":"José Paulo Ribeiro Júnior , Thaís Barros Felippe Jabour , Liana Franco de Sousa Barros , Juliana Carlos Gonçalves Rego","doi":"10.1016/j.abd.2025.501186","DOIUrl":"10.1016/j.abd.2025.501186","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501186"},"PeriodicalIF":3.6,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144842355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of biologics in pediatric-onset hidradenitis suppurativa: a case series 应用生物制剂治疗小儿发作的化脓性汗腺炎：一个病例系列
IF 3.6 4区 医学 Q2 DERMATOLOGY
Anais brasileiros de dermatologia
Pub Date : 2025-08-14 DOI: 10.1016/j.abd.2025.501188
Gilberto Pires da Rosa , Sofia Magina , Carmen Lisboa , Filomena Azevedo , Alberto Mota , Maria João Cruz
{"title":"Use of biologics in pediatric-onset hidradenitis suppurativa: a case series","authors":"Gilberto Pires da Rosa , Sofia Magina , Carmen Lisboa , Filomena Azevedo , Alberto Mota , Maria João Cruz","doi":"10.1016/j.abd.2025.501188","DOIUrl":"10.1016/j.abd.2025.501188","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501188"},"PeriodicalIF":3.6,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144842356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Refractory myelodysplasia cutis in a patient with progression to acute myeloid leukaemia 进展为急性髓性白血病的难治性骨髓发育不良患者
IF 3.6 4区 医学 Q2 DERMATOLOGY
Anais brasileiros de dermatologia
Pub Date : 2025-08-13 DOI: 10.1016/j.abd.2025.501185
Miguel Mansilla-Polo , Daniel Martín-Torregrosa
{"title":"Refractory myelodysplasia cutis in a patient with progression to acute myeloid leukaemia","authors":"Miguel Mansilla-Polo , Daniel Martín-Torregrosa","doi":"10.1016/j.abd.2025.501185","DOIUrl":"10.1016/j.abd.2025.501185","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501185"},"PeriodicalIF":3.6,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Xeroderma Pigmentosum: a 12-year experience in digital dermoscopy and reflectance confocal microscopy follow-up at a Cancer Center in Brazil 着色性干皮病：巴西癌症中心12年的数字皮肤镜和反射共聚焦显微镜随访经验
IF 3.6 4区 医学 Q2 DERMATOLOGY
Anais brasileiros de dermatologia
Pub Date : 2025-08-13 DOI: 10.1016/j.abd.2025.501182
Joyce Gouvêa Freire, Tatiana Cristina Moraes Pinto Blumetti, Rafaela Brito de Paula, Juliana Casagrande Tavoloni Braga

Background

Xeroderma pigmentosum (XP) is an autosomal recessive genetic disorder characterized by a defect in the nucleotide excision repair (NER) pathway, responsible for repairing DNA damage induced by ultraviolet rays. The most common symptom in affected patients is an increased photosensitivity associated with early development of cutaneous and internal malignancies.

Objective

To describe whether the follow-up of xeroderma pigmentosum patients using total body mapping (TBM) with digital dermoscopy (DD) and in vivo reflectance confocal microscopy (RCM) increases early detection of melanoma and reduces unnecessary biopsies of benign melanocytic lesions.

Methods

Twelve XP patients were followed-up with TBM and DD from February 2008 until March 2020. The number of melanocytic lesions excised (NNE) was counted before and after the surveillance with TBM, DD, and RCM.

Results

In the 12-year surveillance period, twelve XP patients were followed-up with TBM, DD, and RCM. The proportion of thinner and in situ melanomas diagnosed increased after the implementation of TBM and DD in the follow-up of this group (from 67% to 82%). The association of technologies caused a reduction in the NNE from 4.02 to 2.88 and promoted early detection of melanoma.

Study limitations

Maintaining regular follow-up with some XP patients can be challenging due to comorbidities and social issues. Although XP is a rare disease, this represents an especially small number of cases.

Conclusion

XP patients are generally submitted to multiple surgical excisions, with high morbidity. Based on this experience, TBM, DD and RCM have improved the early detection of melanoma and reduced the NNE with a positive impact on health and quality of life.
背景：着色性干皮病（XP）是一种常染色体隐性遗传病，其特征是核苷酸切除修复（NER）通路的缺陷，该通路负责修复紫外线引起的DNA损伤。受影响患者最常见的症状是与皮肤和内部恶性肿瘤早期发展相关的光敏性增加。目的探讨采用数字皮肤镜（DD）和体内反射共聚焦显微镜（RCM）对着色性干皮病患者进行全身定位（TBM）随访是否能提高黑色素瘤的早期发现，并减少良性黑色素细胞病变的不必要活检。方法2008年2月至2020年3月对12例XP患者进行TBM和DD随访。在TBM、DD和RCM监测前后，计算黑色素细胞病变切除（NNE）的数量。结果在12年的监测期内，对12例XP患者进行了TBM、DD和RCM的随访。在本组随访中，实施TBM和DD后诊断为更薄和原位黑色素瘤的比例增加（从67%增加到82%）。这些技术使NNE从4.02降低到2.88，并促进了黑色素瘤的早期发现。由于合并症和社会问题，对一些XP患者进行定期随访可能具有挑战性。虽然XP是一种罕见的疾病，但它代表了特别少的病例。结论xp患者多行多次手术切除，发病率高。根据这一经验，TBM、DD和RCM改善了黑色素瘤的早期发现，减少了NNE，对健康和生活质量产生了积极影响。
{"title":"Xeroderma Pigmentosum: a 12-year experience in digital dermoscopy and reflectance confocal microscopy follow-up at a Cancer Center in Brazil","authors":"Joyce Gouvêa Freire,&nbsp;Tatiana Cristina Moraes Pinto Blumetti,&nbsp;Rafaela Brito de Paula,&nbsp;Juliana Casagrande Tavoloni Braga","doi":"10.1016/j.abd.2025.501182","DOIUrl":"10.1016/j.abd.2025.501182","url":null,"abstract":"<div><h3>Background</h3><div>Xeroderma pigmentosum (XP) is an autosomal recessive genetic disorder characterized by a defect in the nucleotide excision repair (NER) pathway, responsible for repairing DNA damage induced by ultraviolet rays. The most common symptom in affected patients is an increased photosensitivity associated with early development of cutaneous and internal malignancies.</div></div><div><h3>Objective</h3><div>To describe whether the follow-up of xeroderma pigmentosum patients using total body mapping (TBM) with digital dermoscopy (DD) and <em>in vivo</em> reflectance confocal microscopy (RCM) increases early detection of melanoma and reduces unnecessary biopsies of benign melanocytic lesions.</div></div><div><h3>Methods</h3><div>Twelve XP patients were followed-up with TBM and DD from February 2008 until March 2020. The number of melanocytic lesions excised (NNE) was counted before and after the surveillance with TBM, DD, and RCM.</div></div><div><h3>Results</h3><div>In the 12-year surveillance period, twelve XP patients were followed-up with TBM, DD, and RCM. The proportion of thinner and <em>in situ</em> melanomas diagnosed increased after the implementation of TBM and DD in the follow-up of this group (from 67% to 82%). The association of technologies caused a reduction in the NNE from 4.02 to 2.88 and promoted early detection of melanoma.</div></div><div><h3>Study limitations</h3><div>Maintaining regular follow-up with some XP patients can be challenging due to comorbidities and social issues. Although XP is a rare disease, this represents an especially small number of cases.</div></div><div><h3>Conclusion</h3><div>XP patients are generally submitted to multiple surgical excisions, with high morbidity. Based on this experience, TBM, DD and RCM have improved the early detection of melanoma and reduced the NNE with a positive impact on health and quality of life.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501182"},"PeriodicalIF":3.6,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relevance of clinical-pathological correlation in the diagnosis of Cutaneous Rosai-Dorfman disease 临床病理相关性在皮肤Rosai-Dorfman病诊断中的意义
IF 3.6 4区 医学 Q2 DERMATOLOGY
Anais brasileiros de dermatologia
Pub Date : 2025-08-13 DOI: 10.1016/j.abd.2025.501180
Carolina Ferreira Baldecerra, Patrícia Imai Zanardi, Rafaella Cristine Zanatta, Silvio Cesar Franco Giovanni Filho, Cássio Rafael Moreira
{"title":"The relevance of clinical-pathological correlation in the diagnosis of Cutaneous Rosai-Dorfman disease","authors":"Carolina Ferreira Baldecerra,&nbsp;Patrícia Imai Zanardi,&nbsp;Rafaella Cristine Zanatta,&nbsp;Silvio Cesar Franco Giovanni Filho,&nbsp;Cássio Rafael Moreira","doi":"10.1016/j.abd.2025.501180","DOIUrl":"10.1016/j.abd.2025.501180","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501180"},"PeriodicalIF":3.6,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful treatment of recalcitrant Sneddon-Wilkinson disease with secukinumab secukinumab成功治疗顽固性Sneddon-Wilkinson病
IF 3.6 4区 医学 Q2 DERMATOLOGY
Anais brasileiros de dermatologia
Pub Date : 2025-08-13 DOI: 10.1016/j.abd.2025.501178
Miguel Mansilla-Polo , Daniel Martín-Torregrosa , Vicent Martínez-Cozar , Rafael Botella-Estrada
{"title":"Successful treatment of recalcitrant Sneddon-Wilkinson disease with secukinumab","authors":"Miguel Mansilla-Polo ,&nbsp;Daniel Martín-Torregrosa ,&nbsp;Vicent Martínez-Cozar ,&nbsp;Rafael Botella-Estrada","doi":"10.1016/j.abd.2025.501178","DOIUrl":"10.1016/j.abd.2025.501178","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501178"},"PeriodicalIF":3.6,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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