Anais brasileiros de dermatologia最新文献

{"title":"The relationship of Fric test responses with an urticaria activity score, urticaria control test and quality of life scales in patients with symptomatic dermographism","authors":"Ömer Faruk Kıraç ,&nbsp;Mustafa Tosun ,&nbsp;Rukiye Yasak Güner ,&nbsp;Melih Akyol","doi":"10.1016/j.abd.2025.501147","DOIUrl":"10.1016/j.abd.2025.501147","url":null,"abstract":"<div><h3>Background</h3><div>The FricTest is used as a valuable tool for diagnosing and conducting threshold testing for Symptomatic Dermographism (SD).</div></div><div><h3>Objective</h3><div>In this study, the authors aimed to make a comparison between the Urticaria Activity Score (UAS), Urticaria Control Test (UCT), Visual Analog Scale (VAS), Dermatology Life Quality Index (DLQI), and Chronic Urticaria-Specific Quality of Life (CU-QoL) used to evaluate disease activity and control in the follow-up of urticaria patients and the Fric Test responses used in the diagnosis of dermographism.</div></div><div><h3>Methods</h3><div>71 patients with SD were included in the study. Fric test 4.0 was performed in all patients at baseline and at month 1. The correlations of Fric test scores with UCT, UAS, VAS, DLQI, and CU-QoL at baseline as well as the changes in responses of treatment in the mean scores at month 1 were performed.</div></div><div><h3>Results</h3><div>In the correlation analyses, positive correlations were observed between UAS, DLQI, and CU-QoL scores and changes in Fric test 4.5 mm and 4 mm responses from baseline to the first month of treatment (<em>p</em> &lt; 0.05). No significant correlations were found between Fric test 3.5 mm and 3 mm responses and CU-QoL, UAS, DLQI, and VAS scores (<em>p</em> &gt; 0.05).</div></div><div><h3>Study limitations</h3><div>This study includes results from a small sample size, and larger-scale clinical trials are needed.</div></div><div><h3>Conclusion</h3><div>Changes in the Fric test 4.5 mm and 4 mm responses of treatment were found to be more sensitive in detecting UCT, UAS, CU-QoL, and DLQI changes than the responses of the Fric test 3.5 mm and 3 mm.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501147"},"PeriodicalIF":2.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144569894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Necrotizing fasciitis caused by Stenotrophomonas maltophilia on the neck of a previously healthy child","authors":"Giovanna Gelli Carrascoza ,&nbsp;Denis Miyashiro ,&nbsp;Murilo Perin da Silva ,&nbsp;Talita Georgeana Baratieri Pinheiro ,&nbsp;Suheyla Pollyana Pereira Ribeiro ,&nbsp;José Antonio Sanches","doi":"10.1016/j.abd.2025.501179","DOIUrl":"10.1016/j.abd.2025.501179","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501179"},"PeriodicalIF":3.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144867322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of biologics in pediatric-onset hidradenitis suppurativa: a case series","authors":"Gilberto Pires da Rosa ,&nbsp;Sofia Magina ,&nbsp;Carmen Lisboa ,&nbsp;Filomena Azevedo ,&nbsp;Alberto Mota ,&nbsp;Maria João Cruz","doi":"10.1016/j.abd.2025.501188","DOIUrl":"10.1016/j.abd.2025.501188","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501188"},"PeriodicalIF":3.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144842356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double invasion: an unprecedented case of metastases from two distinct primary sites coexisting in a single cutaneous lesion","authors":"Matheus Alves Pacheco ,&nbsp;Amanda Amaro Pereira ,&nbsp;Leonardo Simas Abi Saab ,&nbsp;Rúbia Tabata Rigatti ,&nbsp;Oscar Cardoso Dimatos ,&nbsp;Athos Paulo Santos Martini","doi":"10.1016/j.abd.2025.501195","DOIUrl":"10.1016/j.abd.2025.501195","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501195"},"PeriodicalIF":3.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144860359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phaeohyphomycosis caused by Cladosporium cladosporioides: importance of molecular identification in challenging cases","authors":"Olivia Silva Zanetti ,&nbsp;Maria Paula Barbieri D’Elia ,&nbsp;Sigrid de Sousa Dos Santos ,&nbsp;Giannina Ricci","doi":"10.1016/j.abd.2025.501196","DOIUrl":"10.1016/j.abd.2025.501196","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501196"},"PeriodicalIF":3.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144867323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence on inflammatory dermatoses: where we are and where are we going?","authors":"Dimitri Luz F. Silva ,&nbsp;Rafael Rubinho ,&nbsp;Ariany Denofre ,&nbsp;Sandra Avila ,&nbsp;Renata Ferreira Magalhães","doi":"10.1016/j.abd.2025.501164","DOIUrl":"10.1016/j.abd.2025.501164","url":null,"abstract":"<div><h3>Background</h3><div>Artificial intelligence (AI) is increasingly gaining ground in dermatology, with studies reporting accuracy equal to or greater than dermatologists for the diagnosis of skin lesions from clinical and dermoscopic images.<span><span>¹</span></span> AI has been developed and improved constantly for dermatology, however, the focus has been much more on neoplastic diseases, due to their high prevalence and high morbidity.</div></div><div><h3>Objectives</h3><div>Describe the possible applications of AI in inflammatory dermatoses.</div></div><div><h3>Methods</h3><div>Articles published between 2013 and 2023 in Medline and Lilacs were retrieved after applying the inclusion and exclusion criteria 19 articles were selected. From each selected article, the necessary information was extracted and with this data, the present review was written.</div></div><div><h3>Results</h3><div>The first studies on AI in dermatology focused on the diagnosis of neoplasms, especially melanoma, due to the ease of standardization of images, obtaining accuracy equivalent to that of a dermatologist in clinical and dermoscopic lesions. Actually, there are many studies on artificial intelligence in inflammatory dermatosis, such as psoriasis, helping to calculate the PASI, hidradenitis suppurativa, and atopic dematitis.</div></div><div><h3>Study limitations</h3><div>The limitation of the study is that it is a literature review and because it is an innovative topic with a limited number of studies published in the literature.</div></div><div><h3>Conclusions</h3><div>Considerable of what is published in the literature is in computer science journals, but it is possible to perceive that there is an important interest in the area and that artificial intelligence will advance to assist dermatologists.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501164"},"PeriodicalIF":2.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical-demographic profile, aggravating factors, comorbidities, and quality of life in patients with Rosacea: a Brazilian multicenter study (GBPER: Brazilian Research and Studies Group on Rosacea)","authors":"Renan Rangel Bonamigo ,&nbsp;Paula Barea ,&nbsp;Juliano Peruzzo ,&nbsp;Juliana Boza ,&nbsp;Hélio Amante Miot ,&nbsp;Edileia Bagatin ,&nbsp;Luiz Maurício Costa Almeida ,&nbsp;Giovanni Indelicato Milano ,&nbsp;Carla Wanderley Gayoso de Lima ,&nbsp;Linácia Freitas Vidal ,&nbsp;Fabíola Rosa Picosse ,&nbsp;Bruna Manuella de Figueiredo Afonso ,&nbsp;Clivia Maria Moraes de Oliveira","doi":"10.1016/j.abd.2025.501160","DOIUrl":"10.1016/j.abd.2025.501160","url":null,"abstract":"<div><h3>Background</h3><div>Rosacea is the most prevalent chronic vascular-inflammatory dermatosis of the face. Its pathogenesis includes genetic and environmental factors, neurovascular alterations, and innate immunity. Many triggering and aggravating factors, as well as systemic comorbidities, have been associated with the disease, but there are few studies on its epidemiology in Brazil.</div></div><div><h3>Objectives</h3><div>To describe the profile of patients with rosacea treated at referral centers, as well as to investigate the presence of comorbidities, dietary aspects, worsening factors, and quality of life.</div></div><div><h3>Methods</h3><div>Cross-sectional and multicenter Brazilian study. Clinical and demographic data, disease severity, triggering and/or aggravating factors, diet, comorbidities, and impact on quality of life were evaluated.</div></div><div><h3>Results</h3><div>258 patients were included, predominantly women, between 35 and 65 years old and phototypes III, IV and II. The clinical picture ranged from mild to moderate in 89% of cases and quality of life was reasonable to slightly affected in 58% of cases. Aggravating factors for rosacea were reported by 96% of patients, with climate exposure, alcoholic beverages, and emotional changes being the most frequent. Among the foods mentioned as aggravating factors (28%), pepper, other condiments and hot beverages were the most frequently reported. Comorbidities were reported by 89% of the participants, with emphasis on endocrine (48%), psychiatric (35%), cardiovascular (31%) and gastrointestinal (28%) diseases.</div></div><div><h3>Study limitations</h3><div>Uncontrolled study, including patients undergoing dermatological treatment.</div></div><div><h3>Conclusions</h3><div>This study establishes that the profile of Brazilian patients with rosacea corroborates that described in the literature, with the presence of the disease in higher phototypes being relevant. Pepper and other condiments and hot beverages were important aggravating factors, and the presence of various comorbidities was reported by most of the patients.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501160"},"PeriodicalIF":2.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144596847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Xeroderma Pigmentosum: a 12-year experience in digital dermoscopy and reflectance confocal microscopy follow-up at a Cancer Center in Brazil","authors":"Joyce Gouvêa Freire,&nbsp;Tatiana Cristina Moraes Pinto Blumetti,&nbsp;Rafaela Brito de Paula,&nbsp;Juliana Casagrande Tavoloni Braga","doi":"10.1016/j.abd.2025.501182","DOIUrl":"10.1016/j.abd.2025.501182","url":null,"abstract":"<div><h3>Background</h3><div>Xeroderma pigmentosum (XP) is an autosomal recessive genetic disorder characterized by a defect in the nucleotide excision repair (NER) pathway, responsible for repairing DNA damage induced by ultraviolet rays. The most common symptom in affected patients is an increased photosensitivity associated with early development of cutaneous and internal malignancies.</div></div><div><h3>Objective</h3><div>To describe whether the follow-up of xeroderma pigmentosum patients using total body mapping (TBM) with digital dermoscopy (DD) and <em>in vivo</em> reflectance confocal microscopy (RCM) increases early detection of melanoma and reduces unnecessary biopsies of benign melanocytic lesions.</div></div><div><h3>Methods</h3><div>Twelve XP patients were followed-up with TBM and DD from February 2008 until March 2020. The number of melanocytic lesions excised (NNE) was counted before and after the surveillance with TBM, DD, and RCM.</div></div><div><h3>Results</h3><div>In the 12-year surveillance period, twelve XP patients were followed-up with TBM, DD, and RCM. The proportion of thinner and <em>in situ</em> melanomas diagnosed increased after the implementation of TBM and DD in the follow-up of this group (from 67% to 82%). The association of technologies caused a reduction in the NNE from 4.02 to 2.88 and promoted early detection of melanoma.</div></div><div><h3>Study limitations</h3><div>Maintaining regular follow-up with some XP patients can be challenging due to comorbidities and social issues. Although XP is a rare disease, this represents an especially small number of cases.</div></div><div><h3>Conclusion</h3><div>XP patients are generally submitted to multiple surgical excisions, with high morbidity. Based on this experience, TBM, DD and RCM have improved the early detection of melanoma and reduced the NNE with a positive impact on health and quality of life.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501182"},"PeriodicalIF":3.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful treatment of refractory eosinophilic annular erythema with tofacitinib","authors":"Ying-Luo Niu,&nbsp;Hai-Yang He,&nbsp;Sheng Fang","doi":"10.1016/j.abd.2025.501194","DOIUrl":"10.1016/j.abd.2025.501194","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501194"},"PeriodicalIF":3.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144860360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A randomized clinical trial of silver hydrofiber dressing versus collagenase ointment for venous ulcer: analysis of biofilm-producing bacteria and bacterial clonality","authors":"Taís Lopes Saranholi ,&nbsp;Natalie Carlos Ferreira Mello Sampaio ,&nbsp;Hélio Amante Miot ,&nbsp;Stéfani Thais Alves Dantas ,&nbsp;Vera Lucia Mores Rall ,&nbsp;Luciana Patricia Fernandes Abbade","doi":"10.1016/j.abd.2025.501162","DOIUrl":"10.1016/j.abd.2025.501162","url":null,"abstract":"<div><h3>Background</h3><div>Superficial infection in venous ulcers (VU) hinders healing.</div></div><div><h3>Objective</h3><div>To evaluate the action of hydrofiber dressing with silver (HAg) compared to collagenase ointment (Col) in VU.</div></div><div><h3>Methods</h3><div>Randomized controlled clinical trial in which patients with VU with superficial infection were randomized to the intervention (HAg) or comparison (Col) group. After 30 days (T30), the primary outcomes evaluated were: rate of ulcers without signs of superficial infection, decrease in bacterial load, presence of biofilm-producing bacteria, and bacterial clonality.</div></div><div><h3>Results</h3><div>Thirty-four patients (56 ulcers) were included ‒ 18 patients (28 ulcers) in the HAg group and 16 (28 ulcers) in the Col group. There was a reduction in ulcers with superficial infection in both groups over time but with no differences (<em>p</em> = 0.422). There was no decrease in total bacterial load over time (<em>p</em> = 0.054) or between the groups (<em>p</em> = 0.113). There was a reduction in the rate of ulcers with biofilm-forming bacteria over time (<em>p</em> = 0.047) but no differences between groups (<em>p</em> = 0.558). Regarding the clonality of <em>Staphylococcus aureus</em>, 92.8% of ulcers in the HAg group and 85% in the Col group, the clones identified at T0 were the same at T30 (<em>p</em> = 0.553). There was no change in the identity of <em>Pseudomonas aeruginosa</em> in any ulcer in either group.</div></div><div><h3>Study limitations</h3><div>Short follow-up time.</div></div><div><h3>Conclusion</h3><div>Both interventions improved the clinical and some microbiologic characteristics, but there was no difference between both interventions. In addition, most ulcers showed indistinguishable genetic profiles of <em>S. aureus</em> and <em>P. aeruginosa</em> between T0 and T30, with no difference between the groups.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"100 5","pages":"Article 501162"},"PeriodicalIF":2.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144623681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}