Pub Date : 2025-01-13DOI: 10.1016/j.abd.2024.08.004
Gabriel Lazzeri Cortez, Karime Hassun, Luciana Ribeiro Patricio Linhares, Verena Florenço, Maria Valeria Bussamara Pinheiro, Mauricio Mendonça do Nascimento
Male androgenetic alopecia (MAA) is quite common and worsens with age, with a significant impact on quality of life, and is increasingly a reason for consultation with a dermatologist. The etiopathogenesis of MAA is multifactorial and genetic and hormonal influences stand out. MAA starts with the process of follicular miniaturization in diverse phenotypic patterns. The diagnosis of MAA is basically clinical and currently corroborated by well-established trichoscopic findings. Despite this, therapeutic options are limited, especially when one considers medications with a high level of scientific evidence. This review aims to help the general dermatologist towards a better understanding of MAA providing a basis for good individualized and judicious therapeutic decisions.
{"title":"Male androgenetic alopecia.","authors":"Gabriel Lazzeri Cortez, Karime Hassun, Luciana Ribeiro Patricio Linhares, Verena Florenço, Maria Valeria Bussamara Pinheiro, Mauricio Mendonça do Nascimento","doi":"10.1016/j.abd.2024.08.004","DOIUrl":"https://doi.org/10.1016/j.abd.2024.08.004","url":null,"abstract":"<p><p>Male androgenetic alopecia (MAA) is quite common and worsens with age, with a significant impact on quality of life, and is increasingly a reason for consultation with a dermatologist. The etiopathogenesis of MAA is multifactorial and genetic and hormonal influences stand out. MAA starts with the process of follicular miniaturization in diverse phenotypic patterns. The diagnosis of MAA is basically clinical and currently corroborated by well-established trichoscopic findings. Despite this, therapeutic options are limited, especially when one considers medications with a high level of scientific evidence. This review aims to help the general dermatologist towards a better understanding of MAA providing a basis for good individualized and judicious therapeutic decisions.</p>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-13DOI: 10.1016/j.abd.2024.07.007
Florence Robinson, Lucy Webber, Emma Ormerod, Daniel Keith
{"title":"An extremely prolonged case of drug reaction with eosinophilia and systemic symptoms (DRESS Syndrome) secondary to a penicillin-based antibiotic.","authors":"Florence Robinson, Lucy Webber, Emma Ormerod, Daniel Keith","doi":"10.1016/j.abd.2024.07.007","DOIUrl":"https://doi.org/10.1016/j.abd.2024.07.007","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-13DOI: 10.1016/j.abd.2024.07.008
Denis Miyashiro, Regina Barros Domingues, Malu Viter da Rosa Barbosa, Claudia Giuli Santi, Marcello Menta Simonsen Nico, José Antonio Sanches
{"title":"Vulvar ulcers secondary to aortic angiosarcoma in a patient with misdiagnosed cancer of unknown primary origin<sup>⋆</sup>.","authors":"Denis Miyashiro, Regina Barros Domingues, Malu Viter da Rosa Barbosa, Claudia Giuli Santi, Marcello Menta Simonsen Nico, José Antonio Sanches","doi":"10.1016/j.abd.2024.07.008","DOIUrl":"https://doi.org/10.1016/j.abd.2024.07.008","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142982441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10DOI: 10.1016/j.abd.2024.05.010
Nelson Lobos, María José Pereira, Macarena Stevenson, Dan Hartmann, Valentina Darlic, Alex Castro
{"title":"Glomangiosarcoma arising from traumatic lesion in the elbow.","authors":"Nelson Lobos, María José Pereira, Macarena Stevenson, Dan Hartmann, Valentina Darlic, Alex Castro","doi":"10.1016/j.abd.2024.05.010","DOIUrl":"https://doi.org/10.1016/j.abd.2024.05.010","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10DOI: 10.1016/j.abd.2024.01.010
Mengguo Liu
Keloid is a common fibrotic disease, which is difficult to treat. It often causes itching and pain, which greatly disturbs patients in their work and daily life and causing difficulties in social interaction. Its pathogenesis is not clear, but may be related to several aspects: genetic susceptibility, environmental, immunological and endocrine factors, trauma and tension. The central point of its pathogenesis is the excessive proliferation of fibroblasts, with excessive synthesis and secretion of extracellular matrix such as collagen. However, the cause of fibroblast excessive proliferation and differentiation is not clear. Immune abnormalities may play an important role, with cytokines, chemokines, growth factors, and other important immune molecules acting on fibroblasts. This paper presents a detailed and comprehensive literature review on this subject.
{"title":"Cytokines, chemokines and growth factors involved in keloids pathogenesis.","authors":"Mengguo Liu","doi":"10.1016/j.abd.2024.01.010","DOIUrl":"https://doi.org/10.1016/j.abd.2024.01.010","url":null,"abstract":"<p><p>Keloid is a common fibrotic disease, which is difficult to treat. It often causes itching and pain, which greatly disturbs patients in their work and daily life and causing difficulties in social interaction. Its pathogenesis is not clear, but may be related to several aspects: genetic susceptibility, environmental, immunological and endocrine factors, trauma and tension. The central point of its pathogenesis is the excessive proliferation of fibroblasts, with excessive synthesis and secretion of extracellular matrix such as collagen. However, the cause of fibroblast excessive proliferation and differentiation is not clear. Immune abnormalities may play an important role, with cytokines, chemokines, growth factors, and other important immune molecules acting on fibroblasts. This paper presents a detailed and comprehensive literature review on this subject.</p>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10DOI: 10.1016/j.abd.2024.04.014
Lula María Nieto-Benito, Verónica Parra-Blanco, Ricardo María Suárez-Fernández
{"title":"Collagen IV immunohistochemistry and autoimmune bullous diseases: defining the location of the subepidermal bullae.","authors":"Lula María Nieto-Benito, Verónica Parra-Blanco, Ricardo María Suárez-Fernández","doi":"10.1016/j.abd.2024.04.014","DOIUrl":"https://doi.org/10.1016/j.abd.2024.04.014","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-09DOI: 10.1016/j.abd.2024.04.015
Ana Carolina Baião Silva, Helena Maciel Guerra, Leonardo Ávila Ferreira, Rafael Fantelli Stelini, Laura Bertanha, Renata Ferreira Magalhães
{"title":"Superficial acral fibromyxoma with bone involvement: description and postoperative follow-up.","authors":"Ana Carolina Baião Silva, Helena Maciel Guerra, Leonardo Ávila Ferreira, Rafael Fantelli Stelini, Laura Bertanha, Renata Ferreira Magalhães","doi":"10.1016/j.abd.2024.04.015","DOIUrl":"https://doi.org/10.1016/j.abd.2024.04.015","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-09DOI: 10.1016/j.abd.2024.05.006
John Verrinder Veasey, Bruna Cavaleiro de Macedo Souza, Guilherme Camargo Julio Valinoto
{"title":"Dapsone-induced methemoglobinemia in a child with leprosy.","authors":"John Verrinder Veasey, Bruna Cavaleiro de Macedo Souza, Guilherme Camargo Julio Valinoto","doi":"10.1016/j.abd.2024.05.006","DOIUrl":"https://doi.org/10.1016/j.abd.2024.05.006","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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