Anais brasileiros de dermatologia最新文献

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Upadacitinib treatment of refractory livedoid vasculopathy: a case report and literature review 厄帕他替尼治疗难治性类血管病1例报告并文献复习。

IF 3.6 4区医学 Q2 DERMATOLOGY

Anais brasileiros de dermatologia

Pub Date : 2025-11-01 DOI: 10.1016/j.abd.2025.501236

Jiecheng Zheng , Xiaoqian Liang , Xueyi Huang, Jia Liao

引用次数: 0

Knowledge and attitudes towards psoriasis patients among adults: a cross-sectional study from Turkiye 对成人牛皮癣患者的知识和态度：来自土耳其的横断面研究

IF 3.6 4区医学 Q2 DERMATOLOGY

Anais brasileiros de dermatologia

Pub Date : 2025-11-01 DOI: 10.1016/j.abd.2025.501229

Erman Kavlu , Esra Ağaoğlu , Bengisu Karagöz , Hilal Kaya Erdoğan , Muhammed Fatih Önsüz , Selma Metintaş

Background

Misconceptions about psoriasis can negatively influence attitudes toward people diagnosed with the condition as in other developing countries. Health literacy is known to be low, which may further exacerbate negative attitudes toward psoriasis patients.

Objectives

The study aimed to evaluate the attitudes and knowledge levels and associated factors regarding psoriasis among adults in a community-based sample.

Methods

This cross-sectional study was conducted among 715 individuals (aged ≥ 18 years) who presented to a university hospital.

Results

Approximately 60% of the participants in the study did not have sufficient knowledge about psoriasis, and approximately half of them had a negative attitude according to the attitude scale. A moderate negative correlation was found between the psoriasis knowledge score and the psoriasis attitude scale score. According to the multivariate linear regression model, predictors of a positive attitude toward psoriasis were identified as having an income-generating job (Beta; 95% CI: -1.812; -3.052 to -0.572), having heard of psoriasis in medical terminology (-3.946; -5.374 to -2.518), being aware of psoriasis (-3.961; -5.518 to -2.404), having a family member or close individual with a psoriasis diagnosis (-3.961; -4.637 to -1.694), and having an adequate knowledge level regarding psoriasis (-2.880; -4.072 to -1.687) (F = 22.921, p ≤ 0.001, R² = 0.206).

Study limitations

Due to its cross-sectional design, causality could not be established. Additionally, the study was single-centered and based on self-reported data.

Conclusions

The most significant predictor of attitudes toward people with psoriasis was identified as knowledge adequacy.

背景与其他发展中国家一样，对牛皮癣的误解会对人们对牛皮癣诊断的态度产生负面影响。众所周知，健康素养较低，这可能进一步加剧对牛皮癣患者的负面态度。目的了解以社区为基础的成人对银屑病的态度、知识水平及相关因素。方法对某大学医院就诊的715例患者（年龄≥18岁）进行横断面研究。结果约60%的研究对象对银屑病缺乏足够的认识，约一半的研究对象对银屑病持否定态度。银屑病知识得分与银屑病态度量表得分呈中度负相关。根据多元线性回归模型，对银屑病持积极态度的预测因子为：有创收工作（Beta; 95% CI: -1.812; -3.052 ~ -0.572），听说过牛皮癣医学术语（-3.946;-5.374 ~ -2.518），了解牛皮癣（-3.961;-5.518 ~ -2.404），有家庭成员或亲密个体诊断为牛皮癣（-3.961;-4.637 ~ -1.694），对牛皮癣有足够的知识水平(-2.880；-4.072 ~ -1.687) （F = 22.921, p≤0.001,R2 = 0.206）。研究局限性：由于其横断面设计，无法确定因果关系。此外，该研究是单中心的，基于自我报告的数据。结论知识充分性是影响对银屑病患者态度的最重要因素。

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引用次数: 0

Pediatric melanoma in Brazil: an analysis of mortality 巴西儿童黑色素瘤：死亡率分析

IF 3.6 4区医学 Q2 DERMATOLOGY

Anais brasileiros de dermatologia

Pub Date : 2025-11-01 DOI: 10.1016/j.abd.2025.501238

Karina Munhoz de Paula Alve Coelho , José Guilherme Jasper Pickler , Camila Barbosa , Francis Rosseti Pedack , Bruna Louise Silva , Rafael Roesler , Paulo Henrique Condeixa de França , Hercilio Fronza Junior , José Cândido Caldeira Xavier-Junior

引用次数: 0

Acrometastasis in renal cell carcinoma: a case report and literature review 肾细胞癌的肢端转移1例报告并文献复习

IF 3.6 4区医学 Q2 DERMATOLOGY

Anais brasileiros de dermatologia

Pub Date : 2025-11-01 DOI: 10.1016/j.abd.2025.501232

Emre Zekey , Gülcan Saylam Kurtipek , Murat Çelik

引用次数: 0

Anais Brasileiros de Dermatologia: management experiences and perspectives of a Latin American scientific journal –2021-2025 period Anais Brasileiros de Dermatologia：拉丁美洲科学期刊的管理经验和观点-2021-2025年期间

IF 3.6 4区医学 Q2 DERMATOLOGY

Anais brasileiros de dermatologia

Pub Date : 2025-11-01 DOI: 10.1016/j.abd.2025.501240

Sílvio Alencar Marques , Ana Maria Roselino , Hiram Larangeira de Almeida Junior , Luciana Patrícia Fernandes Abbade

引用次数: 0

Histological and immunohistochemical findings in recurrent nevi 复发性痣的组织学和免疫组织化学表现

IF 3.6 4区医学 Q2 DERMATOLOGY

Anais brasileiros de dermatologia

Pub Date : 2025-11-01 DOI: 10.1016/j.abd.2025.501241

Maisa Aparecida Matico Utsumi Okada , Renata Heck , Renato Marchiori Bakos

Background

Recurrent nevi (RN) arise from the incomplete removal of a benign melanocytic lesion. They may present with clinical and dermoscopic characteristics similar to melanomas and are a potential mimic of neoplasia.

Objective

To describe histopathological and immunohistochemical findings of recurrent nevi, including BRAF immunoexpression.

Methods

A cross-sectional study was conducted on 58 recurrent nevi obtained from a previous prospective study. RN were submitted to histopathological and immunohistochemical analysis. The markers HMB-45, Tyrosinase, Ki-67, and BRAF V-600E were used.

Results

A trizonal pattern was observed in 84.5% of cases and is defined by the presence of junctional melanocytic proliferation, scar tissue, and residual dermal nests. Furthermore, architectural asymmetry (56.9%), lentiginous hyperplasia (75.9%), fibrosis (98.4%), lymphocytic infiltrate (96.5%), and melanophages (79.2%) were identified. Dropping off was observed in 1.7%, adnexal involvement in 22.3%, a pagetoid distribution in 30%, and cell atypia in 15%. HMB-45 and tyrosinase were expressed in a gradient and were identified in 98.3% and 91.4%, respectively. Ki-67 was positive in all cases, and the mean proliferative index was 2.83%. BRAF expression was positive in 72.4%.

Study limitations

Limited sample size, evaluation by a single dermatopathologist, targeted immunohistochemical profiling, and the lack of red counterstaining could be potential limitations of the study.

Conclusions

RN are characterized by architectural asymmetry and a trizonal pattern. Nuclear atypia and a pagetoid distribution may be observed. RN cells have a low proliferative index and are positive for HMB-45 and tyrosinase. BRAF expression occurs in most recurrences and is heterogeneous in RN melanocytes.

背景：复发性痣（RN）是由良性黑色素细胞病变不完全切除引起的。它们可能表现出与黑色素瘤相似的临床和皮肤镜特征，是肿瘤的潜在模拟物。目的探讨复发性痣的组织病理学和免疫组化表现，包括BRAF的免疫表达。方法对58例既往前瞻性研究的复发性痣进行横断面分析。进行组织病理学和免疫组织化学分析。标记物为HMB-45、酪氨酸酶、Ki-67、BRAF V-600E。结果84.5%的病例呈三角形，以交界部黑色素细胞增生、瘢痕组织和残余真皮巢为特征。此外，还发现了建筑不对称（56.9%）、透镜状增生（75.9%）、纤维化（98.4%）、淋巴细胞浸润（96.5%）和噬黑素细胞（79.2%）。1.7%的患者出现脱落，22.3%的患者出现附件受累，30%的患者出现页状分布，15%的患者出现细胞异型。HMB-45和酪氨酸酶呈梯度表达，鉴定率分别为98.3%和91.4%。Ki-67阳性，平均增殖指数为2.83%。BRAF表达阳性的占72.4%。研究局限性有限的样本量、单一皮肤病理学家评估、靶向免疫组织化学分析以及缺乏红色反染色可能是该研究的潜在局限性。结论srn具有结构不对称、呈三角形的特点。可观察到核异型性和页状分布。RN细胞增殖指数低，HMB-45和酪氨酸酶阳性。BRAF表达发生在大多数复发中，并且在RN黑素细胞中是异质性的。

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引用次数: 0

Melanoacanthoma of the nipple: two cases with unique clinical presentations 乳头黑棘瘤2例，临床表现独特

IF 3.6 4区医学 Q2 DERMATOLOGY

Anais brasileiros de dermatologia

Pub Date : 2025-11-01 DOI: 10.1016/j.abd.2025.501231

Aysun Sikar Akturk , Esin Diremsizoglu , Nilgün Sayman , Rebiay Kiran , Cigdem Vural

引用次数: 0

Cutaneous leishmaniasis due to Leishmania (L.) mexicana: first imported case reported in Portugal 墨西哥利什曼原虫引起的皮肤利什曼病：葡萄牙报告的首例输入病例。

IF 3.6 4区医学 Q2 DERMATOLOGY

Anais brasileiros de dermatologia

Pub Date : 2025-11-01 DOI: 10.1016/j.abd.2025.501223

Mélissa M. de Carvalho , Sofia Cortes , José Manuel Cristóvão , José Carlos Cardoso , Maria Goreti Catorze , Alexandre Miroux-Catarino

引用次数: 0

Pancreatic panniculitis following endoscopic retrograde cholangiopancreatography (ERCP): a case report 内镜逆行胰胆管造影（ERCP）后胰膜炎1例报告。

IF 3.6 4区医学 Q2 DERMATOLOGY

Anais brasileiros de dermatologia

Pub Date : 2025-11-01 DOI: 10.1016/j.abd.2025.501211

Rebecca Perez de Amorim, Laís Maria Bellaver de Almeida, Hélio Amante Miot, Juliano Vilaverde Schmitt

引用次数: 0

VEXAS syndrome: cutaneous manifestations and UBA1 gene variants in the diagnosis of a rare autoinflammatory syndrome – Case report VEXAS综合征：一种罕见自身炎症综合征的皮肤表现和UBA1基因变异诊断-病例报告

IF 3.6 4区医学 Q2 DERMATOLOGY

Anais brasileiros de dermatologia

Pub Date : 2025-11-01 DOI: 10.1016/j.abd.2025.501233

Isabel Crivelatti, Shirley Massimo de Souza, Oscar Cardoso Dimatos, Gabriella Di Giunta Funchal, Andressa Miozzo Soares, Amanda Amaro Pereira

引用次数: 0

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