Background: Alopecia areata is a highly frequent disease with great variability in clinical presentation, severity, and prognosis. It has a significant negative impact on quality of life, especially in the moderate and severe forms.
Objective: To disseminate guidelines, prepared by a group of Brazilian experts, for the treatment and follow-up of patients with alopecia areata.
Methods: Eight specialists from different university centers with experience in alopecia areata were appointed by the Brazilian Society of Dermatology to reach a consensus on its treatment. Using the adapted DELPHI methodology, relevant elements were considered and then an analysis of the recent literature was carried out and the text produced. Consensus on the guidelines was defined with the approval of at least 70% of the panel of experts.
Results/conclusions: Treatments vary according to patient age and disease severity. Intralesional injectable corticosteroid therapy was considered the first option for localized disease in adults. In severe cases, Janus Kinase inhibitors are the treatment with the highest level of evidence. Systemic corticosteroid therapy and immunosuppressants (corticosteroid-sparing agents) are also options in these cases. Contact immunotherapy (diphencyprone) is an alternative for stable extensive cases. The assessment of side effects is as important as the hair regrowth rate.
{"title":"II Consensus of the Brazilian Society of Dermatology for the treatment of alopecia areata.","authors":"Paulo Müller Ramos, Alessandra Anzai, Bruna Duque-Estrada, Daniel Fernandes Melo, Flavia Sternberg, Leopoldo Duailibe Nogueira Santos, Lorena Dourado Alves, Fabiane Mulinari-Brenner","doi":"10.1016/j.abd.2024.10.001","DOIUrl":"https://doi.org/10.1016/j.abd.2024.10.001","url":null,"abstract":"<p><strong>Background: </strong>Alopecia areata is a highly frequent disease with great variability in clinical presentation, severity, and prognosis. It has a significant negative impact on quality of life, especially in the moderate and severe forms.</p><p><strong>Objective: </strong>To disseminate guidelines, prepared by a group of Brazilian experts, for the treatment and follow-up of patients with alopecia areata.</p><p><strong>Methods: </strong>Eight specialists from different university centers with experience in alopecia areata were appointed by the Brazilian Society of Dermatology to reach a consensus on its treatment. Using the adapted DELPHI methodology, relevant elements were considered and then an analysis of the recent literature was carried out and the text produced. Consensus on the guidelines was defined with the approval of at least 70% of the panel of experts.</p><p><strong>Results/conclusions: </strong>Treatments vary according to patient age and disease severity. Intralesional injectable corticosteroid therapy was considered the first option for localized disease in adults. In severe cases, Janus Kinase inhibitors are the treatment with the highest level of evidence. Systemic corticosteroid therapy and immunosuppressants (corticosteroid-sparing agents) are also options in these cases. Contact immunotherapy (diphencyprone) is an alternative for stable extensive cases. The assessment of side effects is as important as the hair regrowth rate.</p>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-27DOI: 10.1016/j.abd.2024.07.006
Maria Eduarda Duarte de Oliveira, Ronald Godinho de Oliveira Silva, Melissa Moreira Mansur Clemente, Sabrine Teixeira Ferraz Grunewald
{"title":"Representation of images of black skin in pediatric textbooks.","authors":"Maria Eduarda Duarte de Oliveira, Ronald Godinho de Oliveira Silva, Melissa Moreira Mansur Clemente, Sabrine Teixeira Ferraz Grunewald","doi":"10.1016/j.abd.2024.07.006","DOIUrl":"https://doi.org/10.1016/j.abd.2024.07.006","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-22DOI: 10.1016/j.abd.2024.07.001
{"title":"Notice of withdrawal of the article “Pediatric case of trichilemmal cyst arising on the face”","authors":"","doi":"10.1016/j.abd.2024.07.001","DOIUrl":"10.1016/j.abd.2024.07.001","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"99 6","pages":"Page 992"},"PeriodicalIF":2.6,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-05DOI: 10.1016/j.abd.2024.03.004
Kananda Kesye Sousa Nunes, Carlos Alberto Chirano Rodrigues, Antonio Pedro Mendes Schettini, Sinésio Talhari
{"title":"Lobomycosis: single lesion on the lip","authors":"Kananda Kesye Sousa Nunes, Carlos Alberto Chirano Rodrigues, Antonio Pedro Mendes Schettini, Sinésio Talhari","doi":"10.1016/j.abd.2024.03.004","DOIUrl":"10.1016/j.abd.2024.03.004","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"99 6","pages":"Pages 981-983"},"PeriodicalIF":2.6,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142144977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-02DOI: 10.1016/j.abd.2023.06.012
Huizhong Wang , Jingru Sun
{"title":"Pyoderma gangrenosum triggered by secukinumab in a patient with palmoplantar pustulosis","authors":"Huizhong Wang , Jingru Sun","doi":"10.1016/j.abd.2023.06.012","DOIUrl":"10.1016/j.abd.2023.06.012","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"99 6","pages":"Pages 969-972"},"PeriodicalIF":2.6,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142124527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-31DOI: 10.1016/j.abd.2023.02.013
Athos Paulo Santos Martini, Ariel Córdova Rosa, Marcelo Rigatti, Gabriella Di Giunta Funchal, Matheus Hariel Colin Torres, Matheus Alves Pacheco
{"title":"Diagnosis of glomus tumor and preoperative mapping with ultrasonography","authors":"Athos Paulo Santos Martini, Ariel Córdova Rosa, Marcelo Rigatti, Gabriella Di Giunta Funchal, Matheus Hariel Colin Torres, Matheus Alves Pacheco","doi":"10.1016/j.abd.2023.02.013","DOIUrl":"10.1016/j.abd.2023.02.013","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"99 6","pages":"Pages 961-963"},"PeriodicalIF":2.6,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-30DOI: 10.1016/j.abd.2024.01.003
Aline Donati , Isabelle I. Hue Wu
Frontal fibrosing alopecia (FFA) is an inflammatory cicatricial alopecia, which is considered to be a variant of lichen planopilaris. In addition to follicular changes, FFA often presents with associated cutaneous manifestations in most patients, including lichen planus pigmentosus, implantation line hypochromia and facial papules. The objective of the present article is to provide a detailed overview of the non-follicular cutaneous clinical manifestations of FFA and discuss their impact on the diagnosis and treatment of patients with this condition.
{"title":"Extra-follicular cutaneous manifestations of frontal fibrosing alopecia","authors":"Aline Donati , Isabelle I. Hue Wu","doi":"10.1016/j.abd.2024.01.003","DOIUrl":"10.1016/j.abd.2024.01.003","url":null,"abstract":"<div><div>Frontal fibrosing alopecia (FFA) is an inflammatory cicatricial alopecia, which is considered to be a variant of lichen planopilaris. In addition to follicular changes, FFA often presents with associated cutaneous manifestations in most patients, including lichen planus pigmentosus, implantation line hypochromia and facial papules. The objective of the present article is to provide a detailed overview of the non-follicular cutaneous clinical manifestations of FFA and discuss their impact on the diagnosis and treatment of patients with this condition.</div></div>","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"99 6","pages":"Pages 875-886"},"PeriodicalIF":2.6,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-23DOI: 10.1016/j.abd.2023.09.011
Ingrid Priscila Ribeiro Paes Ferraz , Gustavo Carvalho , Juliana Casagrande Tavoloni Braga , Rafaela Brito de Paula , André Molina
{"title":"Confocal reflectance microscopy in basal cell carcinoma associated with nevus sebaceous: case report","authors":"Ingrid Priscila Ribeiro Paes Ferraz , Gustavo Carvalho , Juliana Casagrande Tavoloni Braga , Rafaela Brito de Paula , André Molina","doi":"10.1016/j.abd.2023.09.011","DOIUrl":"10.1016/j.abd.2023.09.011","url":null,"abstract":"","PeriodicalId":7787,"journal":{"name":"Anais brasileiros de dermatologia","volume":"99 6","pages":"Pages 957-960"},"PeriodicalIF":2.6,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}