Pub Date : 2023-11-27DOI: 10.1080/19768354.2023.2285829
Hyung-Bae Jeon, Ho Young Suk
A complete reconstruction of the history regarding the distribution of a species requires a separate analysis of the events before and after colonizing the current distribution. In a freshwater spe...
一个物种分布历史的完整重建需要对殖民当前分布之前和之后的事件进行单独的分析。在淡水中…
{"title":"Genetic structure of Rhodeus sinensis reflects historical imprints of East Asian paleo-drainages","authors":"Hyung-Bae Jeon, Ho Young Suk","doi":"10.1080/19768354.2023.2285829","DOIUrl":"https://doi.org/10.1080/19768354.2023.2285829","url":null,"abstract":"A complete reconstruction of the history regarding the distribution of a species requires a separate analysis of the events before and after colonizing the current distribution. In a freshwater spe...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"AES-20 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138524802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.1080/19768354.2023.2285826
Sung-Hyun Kim, Sumin Yang, Eunjeong Yang, Mingon Kang, Jae-Yeol Joo
Tauopathies as one of the typical neurodegenerative diseases are characterized by pathologically aggregated tau in neuron and glia, which causes dysfunction, synapse loss, and cognitive impairments...
{"title":"Potent of strategic approaches for tauopathies ranging from single-cell transcriptome to microbiome","authors":"Sung-Hyun Kim, Sumin Yang, Eunjeong Yang, Mingon Kang, Jae-Yeol Joo","doi":"10.1080/19768354.2023.2285826","DOIUrl":"https://doi.org/10.1080/19768354.2023.2285826","url":null,"abstract":"Tauopathies as one of the typical neurodegenerative diseases are characterized by pathologically aggregated tau in neuron and glia, which causes dysfunction, synapse loss, and cognitive impairments...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"58 11","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138524800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.1080/19768354.2023.2283763
Sarah J. du Plessis, Sungwon Hong, Boyoung Lee, Klaus-Peter Koepfli, Elizabeth A. Chadwick, Frank Hailer
Eurasian otters (Lutra lutra) have a broad distribution across Eurasia, but biogeographic data outside of western Europe is limited to disconnected pockets. Based on current subspecies designations...
{"title":"Mitochondrial genome-based synthesis and timeline of Eurasian otter (Lutra lutra) phylogeography","authors":"Sarah J. du Plessis, Sungwon Hong, Boyoung Lee, Klaus-Peter Koepfli, Elizabeth A. Chadwick, Frank Hailer","doi":"10.1080/19768354.2023.2283763","DOIUrl":"https://doi.org/10.1080/19768354.2023.2283763","url":null,"abstract":"Eurasian otters (Lutra lutra) have a broad distribution across Eurasia, but biogeographic data outside of western Europe is limited to disconnected pockets. Based on current subspecies designations...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"64 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138524803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hepatocellular carcinoma (HCC) is a frequently occurring malignant gastrointestinal cancer. The 5-year survival rate of HCC is still below 8%, and thus, identifying more effective therapeutic metho...
{"title":"Stigmast-4-en-6β-ol-3-one decreases viability and induces apoptosis and ferroptosis in liver cancer cells by reducing E2F1","authors":"Zhiyun Zhang, Jian Wang, Weiping Wan, Zhengchao Shen, Aixue Zuo, Rong Chen, Qinyi Wu, Enli Cai, Feng Huang, Rongping Zhang, Xinan Shi","doi":"10.1080/19768354.2023.2282224","DOIUrl":"https://doi.org/10.1080/19768354.2023.2282224","url":null,"abstract":"Hepatocellular carcinoma (HCC) is a frequently occurring malignant gastrointestinal cancer. The 5-year survival rate of HCC is still below 8%, and thus, identifying more effective therapeutic metho...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"37 9","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138524799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-21DOI: 10.1080/19768354.2023.2281370
Wonyi Jang, Mijung Im, Jungwook Roh, JiHoon Kang, Wanyeon Kim
The Hippo signaling pathway is a conserved signaling pathway that regulates cell proliferation, apoptosis, and differentiation and plays essential roles in the maintenance of organ size and tissue ...
{"title":"Hippo-YAP/TAZ pathway regulation: the crucial roles of lncRNAs in cancer","authors":"Wonyi Jang, Mijung Im, Jungwook Roh, JiHoon Kang, Wanyeon Kim","doi":"10.1080/19768354.2023.2281370","DOIUrl":"https://doi.org/10.1080/19768354.2023.2281370","url":null,"abstract":"The Hippo signaling pathway is a conserved signaling pathway that regulates cell proliferation, apoptosis, and differentiation and plays essential roles in the maintenance of organ size and tissue ...","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"9 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138524784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-15eCollection Date: 2023-01-01DOI: 10.1080/19768354.2023.2282726
Hyun Myoung Yun, Seogang Hyun
The gut microbiome plays a crucial role in maintaining health in a variety of organisms, from insects to humans. Further, beneficial symbiotic microbes are believed to contribute to improving the quality of life of the host. Drosophila is an optimal model for studying host-commensal microbe interactions because it allows for convenient manipulation of intestinal microbial composition. Fly microbiota has a simple taxonomic composition and can be cultivated and genetically tracked. This permits functional studies and analyses of the molecular mechanisms underlying their effects on host physiological processes. In this context, we briefly introduce the principle of juvenile developmental growth in Drosophila. Then, we discuss the current understanding of the molecular mechanisms underlying the effects of gut commensal bacteria, such as Lactiplantibacillus plantarum and Acetobacter pomorum, in the fly gut microbiome on Drosophila juvenile growth, including specific actions of gut hormones and metabolites in conserved cellular signaling systems, such as the insulin/insulin-like (IIS) and the target of rapamycin (TOR) pathways. Given the similarities in tissue function/structure, as well as the high conservation of physiological systems between Drosophila and mammals, findings from the Drosophila model system will have significant implications for understanding the mechanisms underlying the interaction between the host and the gut microbiome in metazoans.
{"title":"Role of gut commensal bacteria in juvenile developmental growth of the host: insights from <i>Drosophila</i> studies.","authors":"Hyun Myoung Yun, Seogang Hyun","doi":"10.1080/19768354.2023.2282726","DOIUrl":"https://doi.org/10.1080/19768354.2023.2282726","url":null,"abstract":"<p><p>The gut microbiome plays a crucial role in maintaining health in a variety of organisms, from insects to humans. Further, beneficial symbiotic microbes are believed to contribute to improving the quality of life of the host. <i>Drosophila</i> is an optimal model for studying host-commensal microbe interactions because it allows for convenient manipulation of intestinal microbial composition. Fly microbiota has a simple taxonomic composition and can be cultivated and genetically tracked. This permits functional studies and analyses of the molecular mechanisms underlying their effects on host physiological processes. In this context, we briefly introduce the principle of juvenile developmental growth in <i>Drosophila</i>. Then, we discuss the current understanding of the molecular mechanisms underlying the effects of gut commensal bacteria, such as <i>Lactiplantibacillus plantarum</i> and <i>Acetobacter pomorum</i>, in the fly gut microbiome on <i>Drosophila</i> juvenile growth, including specific actions of gut hormones and metabolites in conserved cellular signaling systems, such as the insulin/insulin-like (IIS) and the target of rapamycin (TOR) pathways. Given the similarities in tissue function/structure, as well as the high conservation of physiological systems between <i>Drosophila</i> and mammals, findings from the <i>Drosophila</i> model system will have significant implications for understanding the mechanisms underlying the interaction between the host and the gut microbiome in metazoans.</p>","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"27 1","pages":"329-339"},"PeriodicalIF":2.9,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138457362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-14DOI: 10.1080/19768354.2023.2275613
Kyung-Ha Lee
The internal ribosome entry site (IRES) is a unique structure found in the 5’ untranslated region (5'-UTR) of specific messenger RNAs (mRNAs) that allows ribosomes to bind and initiate translation without the need for a cap structure. In this study, we investigated the presence and functional properties of the IRES activity of nitric oxide synthase 2 (NOS2) mRNA, which encodes an enzyme that produces nitric oxide in response to various stimuli such as inflammation. Nitric oxide is a signaling molecule that plays a crucial role in various physiological processes, including immune responses and neuronal signaling. Our results showed the existence of IRES activity in the 5'-UTR of Nos2 mRNA in various cell types. IRES-mediated translation of NOS2 mRNA was higher in neuronal cells and its activity increased in response to lipopolysaccharide (LPS). Despite inhibition of cap-dependent translation, nitrite production was partially maintained. These results demonstrate the presence of IRES activity in the 5'-UTR of NOS2 mRNA and suggest that IRES-mediated translation plays a key role in controlling nitric oxide production in response to LPS, an inflammatory stimulus.
{"title":"Internal ribosomal entry site-mediated translational activity of nitric oxide synthase 2","authors":"Kyung-Ha Lee","doi":"10.1080/19768354.2023.2275613","DOIUrl":"https://doi.org/10.1080/19768354.2023.2275613","url":null,"abstract":"The internal ribosome entry site (IRES) is a unique structure found in the 5’ untranslated region (5'-UTR) of specific messenger RNAs (mRNAs) that allows ribosomes to bind and initiate translation without the need for a cap structure. In this study, we investigated the presence and functional properties of the IRES activity of nitric oxide synthase 2 (NOS2) mRNA, which encodes an enzyme that produces nitric oxide in response to various stimuli such as inflammation. Nitric oxide is a signaling molecule that plays a crucial role in various physiological processes, including immune responses and neuronal signaling. Our results showed the existence of IRES activity in the 5'-UTR of Nos2 mRNA in various cell types. IRES-mediated translation of NOS2 mRNA was higher in neuronal cells and its activity increased in response to lipopolysaccharide (LPS). Despite inhibition of cap-dependent translation, nitrite production was partially maintained. These results demonstrate the presence of IRES activity in the 5'-UTR of NOS2 mRNA and suggest that IRES-mediated translation plays a key role in controlling nitric oxide production in response to LPS, an inflammatory stimulus.","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"7 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134954020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-10DOI: 10.1080/19768354.2023.2276815
Minsoo Kim, Woonhee Kim, ChiHye Chung
Depressive disorders are more prevalent and severe in women; however, our knowledge of the underlying factors contributing to female vulnerability to depression remains limited. Additionally, females are notably underrepresented in studies seeking to understand the mechanisms of depression. Various animal models of depression have been devised, but only recently have females been included in research. In this comprehensive review, we aim to describe the sex differences in the prevalence, pathophysiology, and responses to drug treatment in patients with depression. Subsequently, we highlight animal models of depression in which both sexes have been studied, in the pursuit of identifying models that accurately reflect female vulnerability to depression. We also introduce explanations for the neural basis of sex differences in depression. Notably, the medial prefrontal cortex and the nucleus accumbens have exhibited sex differences in previous studies. Furthermore, other brain circuits involving the dopaminergic center (ventral tegmental area) and the serotonergic center (dorsal raphe nucleus), along with their respective projections, have shown sex differences in relation to depression. In conclusion, our review covers the critical aspects of sex differences in depression, with a specific focus on female vulnerability in humans and its representation in animal models, including the potential underlying mechanisms. Employing suitable animal models that effectively represent female vulnerability would benefit our understanding of the sex-dependent pathophysiology of depression.
{"title":"The neural basis underlying female vulnerability to depressive disorders","authors":"Minsoo Kim, Woonhee Kim, ChiHye Chung","doi":"10.1080/19768354.2023.2276815","DOIUrl":"https://doi.org/10.1080/19768354.2023.2276815","url":null,"abstract":"Depressive disorders are more prevalent and severe in women; however, our knowledge of the underlying factors contributing to female vulnerability to depression remains limited. Additionally, females are notably underrepresented in studies seeking to understand the mechanisms of depression. Various animal models of depression have been devised, but only recently have females been included in research. In this comprehensive review, we aim to describe the sex differences in the prevalence, pathophysiology, and responses to drug treatment in patients with depression. Subsequently, we highlight animal models of depression in which both sexes have been studied, in the pursuit of identifying models that accurately reflect female vulnerability to depression. We also introduce explanations for the neural basis of sex differences in depression. Notably, the medial prefrontal cortex and the nucleus accumbens have exhibited sex differences in previous studies. Furthermore, other brain circuits involving the dopaminergic center (ventral tegmental area) and the serotonergic center (dorsal raphe nucleus), along with their respective projections, have shown sex differences in relation to depression. In conclusion, our review covers the critical aspects of sex differences in depression, with a specific focus on female vulnerability in humans and its representation in animal models, including the potential underlying mechanisms. Employing suitable animal models that effectively represent female vulnerability would benefit our understanding of the sex-dependent pathophysiology of depression.","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"123 28","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135136889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-26DOI: 10.1080/19768354.2023.2272989
Junyong Song, Yu-Hyeon Park, Taein Kim, Soo-Kwon Park, Tae-Hwan Jun, Sang-Gyu Kim
{"title":"A push–pull strategy for controlling <i>Riptortus pedestris</i> (Hemiptera: Alydidae) using host plant semiochemicals","authors":"Junyong Song, Yu-Hyeon Park, Taein Kim, Soo-Kwon Park, Tae-Hwan Jun, Sang-Gyu Kim","doi":"10.1080/19768354.2023.2272989","DOIUrl":"https://doi.org/10.1080/19768354.2023.2272989","url":null,"abstract":"","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134907996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-26DOI: 10.1080/19768354.2023.2273467
Eman Mumtaz El Mahdy, Maha Gamal, Basma Emad Aboulhoda, Basent Adel Al Dreny, Ashraf Shamaa, Laila Rashed, Ahmed Nour Eldine Abdallah, Asmaa M. Shamseldeen
{"title":"Amelioration of rotenone-induced Parkinson's disease; comparing therapeutic role of erythropoietin versus low-level laser activation of mesenchymal stem cells (an in-vivo and in-vitro study)","authors":"Eman Mumtaz El Mahdy, Maha Gamal, Basma Emad Aboulhoda, Basent Adel Al Dreny, Ashraf Shamaa, Laila Rashed, Ahmed Nour Eldine Abdallah, Asmaa M. Shamseldeen","doi":"10.1080/19768354.2023.2273467","DOIUrl":"https://doi.org/10.1080/19768354.2023.2273467","url":null,"abstract":"","PeriodicalId":7804,"journal":{"name":"Animal Cells and Systems","volume":"333 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134907674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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