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Diagnosing Periprosthetic Joint Infection: a Scoping Review. 假体周围关节感染的诊断:范围界定综述。
Pub Date : 2022-06-01 Epub Date: 2022-04-04 DOI: 10.1007/s12178-022-09751-w
Aaron Gazendam, Thomas J Wood, Daniel Tushinski, Kamal Bali

Purpose of review: The goal of this review is to provide an up to date understanding of the utility and limitations of the current tests utilized in the diagnosis of periprosthetic joint infection (PJI) in total knee and hip arthroplasty.

Recent findings: Despite the growth in literature surrounding PJI diagnosis, there remains challenges in establishing a diagnosis of PJI. A combination of clinical, serum, and synovial tests and microbiologic and histologic examinations can yield a diagnosis in the majority of cases. Novel molecular and imaging studies may be beneficial for indeterminant cases. A number of emerging diagnostic tests have been proposed and may be incorporated into diagnostic algorithms in the future. Recently proposed stepwise diagnostic algorithms have shown high sensitivity and specificity. The diagnosis of PJI remains challenging due to a lack of tests that can definitively rule out infection. Diagnosis and investigations should occur in a stepwise fashion. There has been a plethora of new diagnostic tests introduced in attempts to improve the accuracy of diagnostic algorithms. The definition and algorithms for the diagnoses of PJI will continue to evolve as new techniques and tests are introduced.

综述目的:本综述旨在提供对目前用于诊断全膝关节和髋关节置换术中假体周围关节感染(PJI)的检测方法的实用性和局限性的最新认识:尽管有关 PJI 诊断的文献不断增加,但在确定 PJI 诊断方面仍存在挑战。临床、血清和滑膜检测以及微生物学和组织学检查相结合,可对大多数病例做出诊断。新的分子和成像研究可能会对不确定的病例有所帮助。一些新出现的诊断测试已被提出,并可能在未来被纳入诊断算法。最近提出的逐步诊断算法显示出较高的灵敏度和特异性。由于缺乏能明确排除感染的检查,PJI 的诊断仍具有挑战性。诊断和检查应循序渐进。为了提高诊断算法的准确性,已经引入了大量新的诊断测试。随着新技术和检测方法的引入,PJI 的诊断定义和算法也将不断发展。
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引用次数: 0
Single and multiple drug opiate users: addicts or nonaddicts? 单一和多种药物阿片使用者:成瘾者或非成瘾者?
Pub Date : 1972-02-01
W C Lucas, S E Grupp, R L Schmitt
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引用次数: 0
Health care in the nation's capital during 30 mass assemblies. 在30个群众集会期间,国家首都的医疗保健。
Pub Date : 1972-02-01
C R Hayman, H S Meek, R L Standard, M C Hope
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引用次数: 0
Single and multiple drug opiate users: addicts or nonaddicts? 单一和多种阿片类药物使用者:瘾君子还是非瘾君子?
Pub Date : 1972-02-01 DOI: 10.2307/4594463
W. Lucas, S. Grupp, R. L. Schmitt
ATTENTION has been increasingly focused on the users of multiple drugs by drug abuse researchers. Several authors have stated that, viewed in long-term trends, the single drug user is being replaced by a multiple drug user whose intake might include heroin, amphetamines, barbiturates, and psychedelics-either in combination or on successive occurrences (1-4). The question of multiple drug use becomes more complicated if the multiple drug users are, in fact, addicted to the drug or drugs they are taking. In a 1966 study in New York City, Abeles and co-workers noted that multiple drug use was increasing and that many persons were addicted to opiates and barbiturates (3). The problem of multiple drug use is exacerbated because treatment for withdrawal from one type of drug, such as heroin, may lead to the neglect of withdrawal stress from another type of drug, for example, barbiturates. As Abeles and co-workers pointed out, if one neglects the withdrawal symptoms caused by barbiturates, the patient may suffer serious convulsions which can result in death (3). Freedman also noted that many of today's addicts are multiple drug users. He contends that a decade ago the addict was generally using only
药物滥用研究人员越来越多地关注多种药物的使用者。一些作者指出,从长期趋势来看,单一吸毒者正在被多种吸毒者所取代,这些吸毒者的摄入可能包括海洛因、安非他明、巴比妥酸盐和致幻剂——要么是联合服用,要么是连续服用(1-4)。如果多重吸毒者实际上对他们正在服用的药物上瘾,那么多重药物使用的问题就会变得更加复杂。在1966年纽约市的一项研究中,Abeles和他的同事注意到,多种药物的使用正在增加,许多人对阿片类药物和巴比妥类药物上瘾(3)。多种药物使用的问题加剧了,因为对戒断一种药物(如海洛因)的治疗可能导致对戒断另一种药物(如巴比妥类药物)的压力的忽视。正如Abeles及其同事所指出的,如果忽视巴比妥类药物引起的戒断症状,患者可能会出现严重的抽搐,从而导致死亡(3)。Freedman还指出,当今许多成瘾者都是多重吸毒者。他认为,十年前,瘾君子通常只使用毒品
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引用次数: 2
Blindness prevalence rates in Egypt. 埃及的失明患病率。
Pub Date : 1972-02-01 DOI: 10.2307/4594462
M. Said, H. Goldstein, A. Korra, K. El-kashlan
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引用次数: 1
Health care in the nation's capital during 30 mass assemblies. 在30个群众集会期间,国家首都的医疗保健。
Pub Date : 1972-02-01 DOI: 10.2307/4594437
C. Hayman, H. S. Meek, R. Standard, M. Hope
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引用次数: 2
Infectious hepatitis outbreak associated with cafe water. 与咖啡水有关的传染性肝炎爆发。
Pub Date : 1972-02-01 DOI: 10.2307/4594460
R. Garibaldi, G. Murphy, B. T. Wood
BETWEEN July 1, 1969, and July 1, 1970, a total of 53,039 cases of infectious hepatitis were reported to the Center for Disease Control (CDC) by State health departments ('1). In the same period CDC investigated four unrelated waterborne outbreaks of infectious hepatitis comprising 190 cases (references 2-4 and an outbreak in North Carolina, described by Dr. J. D. Hamilton at the Epidemic Intelligence Service Conference in Atlanta, Ga., in April 1970). Although other outbreaks may
在1969年7月1日至1970年7月1日之间,国家卫生部门向疾病控制中心(CDC)报告了总共53039例传染性肝炎病例(1)。在同一时期,疾病预防控制中心调查了四起不相关的水传播传染性肝炎暴发,包括190例(参考文献2-4)和北卡罗来纳州的一次暴发,由J. D. Hamilton博士在佐治亚州亚特兰大举行的流行病情报服务会议上描述。, 1970年4月)。尽管其他疫情可能
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引用次数: 3
Usefulness of factor and cluster analysis in grouping census tracts. 因子和聚类分析在分组人口普查区中的有效性。
Pub Date : 1972-02-01
I Lehr, H B Messinger, E S Rogers
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引用次数: 0
Infectious hepatitis outbreak associated with cafe water. 与咖啡水有关的传染性肝炎爆发。
Pub Date : 1972-02-01
R A Garibaldi, G D Murphy, B T Wood
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引用次数: 0
Impending shortage of cytotechnologists. 迫在眉睫的细胞技术人员短缺。
Pub Date : 1972-02-01
D Johnson
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引用次数: 0
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