Pub Date : 2025-01-10DOI: 10.1016/j.ancard.2024.101854
Marie Nina Koffi, Anicet Kassi Adoubi, Fatouma Sall, Loa Ambroise Gnaba, Florent Diby, Serge Armel Dakoi, Esaïe Soya
Introduction: The aim of the study was to assess the level of treatment optimization after follow-up at discharge.
Methods: We conducted a retrospective study carried out from January 1st, 2016 to December 31st, 2018 in Abidjan Heart Institute with patients hospitalized for heart failure and reviewed in consultation.
Results: The study involved 350 patients with an average age of 53.53 ± 16.38 years (54% were males). The prescription of diuretics (92%) after optimization was at the mean and with maximum doses of 29.1% and 7.7%. ACEIs/ARBs (77.1%) had optimal and mean doses for ACEIs of 14.3% and 29.7%. With beta-blockers (72.6%) there was an improvement in doses at 35.4% for the average doses and 3.1%. for the maximum dose. Spironolactone (44.3%) kept the same average dose at 5.7% The median time of optimization was 287.05 days with a median of 140 days. Only 13.4% of patients were receiving optimal treatment at optimal doses. By logistic regression, the presence of LVEF ≤ 0,40 or LVEF= 0.41-0.49 or global heart failure (P < 0.001) favored drug optimization (OR = 24.68[7.15-82.22], P < 0.001); (OR = 11.39[3.25-39.86], P < 0.001) on the other hand, a high serum creatinine level was an obstacle for treatment optimization (OR = 0.92[0.88-0.96], P < 0.001).
Conclusion: The optimization of the treatment of heart failure is insufficient with too long delays in our context. The optimization time was so long. It could be improved by setting up a clinic to optimize the treatment of heart failure.
前言:本研究的目的是评估出院后随访的治疗优化水平。方法:我们对2016年1月1日至2018年12月31日在阿比让心脏研究所因心力衰竭住院的患者进行回顾性研究,并进行会诊。结果:共纳入350例患者,平均年龄53.53±16.38岁,其中男性占54%。优化后的利尿剂处方(92%)平均、最大剂量分别为29.1%和7.7%。acei / arb(77.1%)的最佳和平均acei剂量分别为14.3%和29.7%。使用-受体阻滞剂(72.6%)时,平均剂量的改善率为35.4%,3.1%。最大剂量。螺内酯(44.3%)平均用量为5.7%,优化时间中位数为287.05 d,中位数为140 d。只有13.4%的患者接受了最佳剂量的最佳治疗。通过logistic回归分析,LVEF≤0,40或LVEF= 0.41-0.49或整体心力衰竭(P < 0.001)有利于药物优化(or = 24.68[7.15-82.22], P < 0.001);(OR = 11.39[3.25-39.86], P < 0.001)另一方面,血清肌酐水平高是优化治疗的障碍(OR = 0.92[0.88-0.96], P < 0.001)。结论:我国对心力衰竭治疗的优化不足,延误时间过长。优化时间太长了。可以通过建立一个诊所来优化心力衰竭的治疗来改善这种情况。
{"title":"[Optimization of heart failure treatment in Abidjan heart institute].","authors":"Marie Nina Koffi, Anicet Kassi Adoubi, Fatouma Sall, Loa Ambroise Gnaba, Florent Diby, Serge Armel Dakoi, Esaïe Soya","doi":"10.1016/j.ancard.2024.101854","DOIUrl":"https://doi.org/10.1016/j.ancard.2024.101854","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of the study was to assess the level of treatment optimization after follow-up at discharge.</p><p><strong>Methods: </strong>We conducted a retrospective study carried out from January 1st, 2016 to December 31st, 2018 in Abidjan Heart Institute with patients hospitalized for heart failure and reviewed in consultation.</p><p><strong>Results: </strong>The study involved 350 patients with an average age of 53.53 ± 16.38 years (54% were males). The prescription of diuretics (92%) after optimization was at the mean and with maximum doses of 29.1% and 7.7%. ACEIs/ARBs (77.1%) had optimal and mean doses for ACEIs of 14.3% and 29.7%. With beta-blockers (72.6%) there was an improvement in doses at 35.4% for the average doses and 3.1%. for the maximum dose. Spironolactone (44.3%) kept the same average dose at 5.7% The median time of optimization was 287.05 days with a median of 140 days. Only 13.4% of patients were receiving optimal treatment at optimal doses. By logistic regression, the presence of LVEF ≤ 0,40 or LVEF= 0.41-0.49 or global heart failure (P < 0.001) favored drug optimization (OR = 24.68[7.15-82.22], P < 0.001); (OR = 11.39[3.25-39.86], P < 0.001) on the other hand, a high serum creatinine level was an obstacle for treatment optimization (OR = 0.92[0.88-0.96], P < 0.001).</p><p><strong>Conclusion: </strong>The optimization of the treatment of heart failure is insufficient with too long delays in our context. The optimization time was so long. It could be improved by setting up a clinic to optimize the treatment of heart failure.</p>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"101854"},"PeriodicalIF":0.3,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10DOI: 10.1016/j.ancard.2024.101859
A Soufiani, Z Agoumy, M Tribak, S El Mhadi, Z Fassi Fehri, H Chraibi, L Bakamel, O Soussi, H El Assili, K Berrag, J Raoui, F Z Hattab, Z Idrissi, S Essebany, H Leghlimi, F Lachhab, N Fellat, R Fellat, A Bensouda, A Chaib, N Bendagha, S Moughil
Background: Surgical management of patients with severe aortic regurgitation (AR) in the setting of significantly impaired left ventricle (LV) function generally carries very high operative risk. The aim of this study is to assess the short and long-term outcomes of aortic valve replacement (AVR) in a selected young Moroccan population.
Materiel and methods: This is a retrospective study between January 2008 and June 2022 including all patients who underwent AVR for massive isolated AR with an LV ejection fraction EF ≤35%.
Results: In this center, a total of 3820 patients were operated for valvular disease, from which 110 had important AR. Overall, 42 patients of 110 patients had an LV ejection fraction≤35%, and benefited from AVR. Rheumatic cause was predominant (50%). Preoperative characteristics find an average age of 46.3 ±14.4 years with male prevalence. Only two deaths are noted in the immediate postoperative period. At the 15 years follow-up, the survival was 86.8%. Clinical improvement was present in the majority of patients. The mean LVEF post-AVR has increased by an average of 16% with proof of reverse remodeling.
Conclusions: In this series, patients benefited largely from AVR with good postoperative outcomes. The global operative mortality was acceptable (4.7%). The long-term survival (86.8%) was better than that described in the western series. Therefore, our results should encourage a surgical approach for those patients.
{"title":"[Résultats chirurgicaux prometteurs à long terme du remplacement valvulaire aortique chez les patients présentant une régurgitation aortique isolée importante et une dysfonction ventriculaire gauche sévère].","authors":"A Soufiani, Z Agoumy, M Tribak, S El Mhadi, Z Fassi Fehri, H Chraibi, L Bakamel, O Soussi, H El Assili, K Berrag, J Raoui, F Z Hattab, Z Idrissi, S Essebany, H Leghlimi, F Lachhab, N Fellat, R Fellat, A Bensouda, A Chaib, N Bendagha, S Moughil","doi":"10.1016/j.ancard.2024.101859","DOIUrl":"https://doi.org/10.1016/j.ancard.2024.101859","url":null,"abstract":"<p><strong>Background: </strong>Surgical management of patients with severe aortic regurgitation (AR) in the setting of significantly impaired left ventricle (LV) function generally carries very high operative risk. The aim of this study is to assess the short and long-term outcomes of aortic valve replacement (AVR) in a selected young Moroccan population.</p><p><strong>Materiel and methods: </strong>This is a retrospective study between January 2008 and June 2022 including all patients who underwent AVR for massive isolated AR with an LV ejection fraction EF ≤35%.</p><p><strong>Results: </strong>In this center, a total of 3820 patients were operated for valvular disease, from which 110 had important AR. Overall, 42 patients of 110 patients had an LV ejection fraction≤35%, and benefited from AVR. Rheumatic cause was predominant (50%). Preoperative characteristics find an average age of 46.3 ±14.4 years with male prevalence. Only two deaths are noted in the immediate postoperative period. At the 15 years follow-up, the survival was 86.8%. Clinical improvement was present in the majority of patients. The mean LVEF post-AVR has increased by an average of 16% with proof of reverse remodeling.</p><p><strong>Conclusions: </strong>In this series, patients benefited largely from AVR with good postoperative outcomes. The global operative mortality was acceptable (4.7%). The long-term survival (86.8%) was better than that described in the western series. Therefore, our results should encourage a surgical approach for those patients.</p>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"101859"},"PeriodicalIF":0.3,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10DOI: 10.1016/j.ancard.2024.101855
I Atlas, M Khaldi, S Hayar, M Haboub, S Arous, E M Benouna, A Drighil, R Habbal
Introduction: Mature teratomas, a diverse group of germ cell tumors, rarely present with complications such as rupture.
Case presentation: We present a case of a 27-year-old male who was admitted to our hospital with acute dyspnea. A tamponade was diagnosed and the patient underwent a pericardial puncture. Further radiological investigations revealed a large mediastinal teratoma with evidence of rupture, leading to pericardial effusion. Surgical intervention was performed, which involved pericardial drainage and complete resection of the teratoma. Histopathological examination confirmed the diagnosis of a mature teratoma. The patient made a full recovery postoperatively.
Discussion: This rare case underscores the importance of early recognition and prompt surgical management in patients with ruptured mediastinal teratomas to prevent complications. We discuss the clinical presentation, diagnostic workup, and surgical approach to aid in the understanding and management of similar cases.
Conclusion: Mature teratomas are relatively rare benign tumors that rarely present with complications such as tamponade. Management of tamponade remains the same, and complete surgical removal of the teratoma is essential. In general, the outcome is favorable after surgical treatment.
{"title":"[Tamponnade due à la rupture d'un tératome mature : un cas rare].","authors":"I Atlas, M Khaldi, S Hayar, M Haboub, S Arous, E M Benouna, A Drighil, R Habbal","doi":"10.1016/j.ancard.2024.101855","DOIUrl":"https://doi.org/10.1016/j.ancard.2024.101855","url":null,"abstract":"<p><strong>Introduction: </strong>Mature teratomas, a diverse group of germ cell tumors, rarely present with complications such as rupture.</p><p><strong>Case presentation: </strong>We present a case of a 27-year-old male who was admitted to our hospital with acute dyspnea. A tamponade was diagnosed and the patient underwent a pericardial puncture. Further radiological investigations revealed a large mediastinal teratoma with evidence of rupture, leading to pericardial effusion. Surgical intervention was performed, which involved pericardial drainage and complete resection of the teratoma. Histopathological examination confirmed the diagnosis of a mature teratoma. The patient made a full recovery postoperatively.</p><p><strong>Discussion: </strong>This rare case underscores the importance of early recognition and prompt surgical management in patients with ruptured mediastinal teratomas to prevent complications. We discuss the clinical presentation, diagnostic workup, and surgical approach to aid in the understanding and management of similar cases.</p><p><strong>Conclusion: </strong>Mature teratomas are relatively rare benign tumors that rarely present with complications such as tamponade. Management of tamponade remains the same, and complete surgical removal of the teratoma is essential. In general, the outcome is favorable after surgical treatment.</p>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"101855"},"PeriodicalIF":0.3,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10DOI: 10.1016/j.ancard.2024.101858
Kaoutar Chafiq, Kaoutar Dib, Ahmed Zahidi, Mohamed Cherti, Anass Doukkali, Kaoutar El Menzhi
Introduction: We live in the era of information technology (IT) innovations in the health sector, this has led to the appropriation of new organizational models which are profoundly changing the practice of medicine. Our study aims to determine the challenges of new digital technologies in the Moroccan health system, the case of the cardiology department - B - of the Ibn Sina University Hospital Center.
Materials and methods: This is a single-center observational descriptive-analytical study carried out at the level of the cardiology department - B- for 6 months, from September 1, 2022. Questionnaires were distributed in paper form to staff-affiliated medical doctor or carrying out their internships, using a digital device within the service.
Results: Thirty-one (31) responses were collected, with a participation rate of 78%; the age of the respondents varies between 21 to 55 years with an average of 30.3± 8.71 years with a female predominance of 67.7% and almost half of the health professionals in our sample 42% were residents. The most deployed digital device is the Hospital Information System (HIS) in 80.6%; 93.5% of respondents noted that saving of time is one of the advantages of telemedicine and 71% of respondents who affirmed that the better monitoring of patients located in isolated areas in order to avoid forgoing care. 74.2% of respondents considered that technical problems constituted an obstacle to the deployment of remote procedures; compared to 22.2% for a weak diagnosis; 64.5% of respondents noted that training would be a major lever for integrating more remote activities into their practices and 54.5% of respondents are in favor of adapted time slots.
Conclusion: The benefits perceived by respondents of these digital tools are numerous, although there are obstacles preventing digital transformation from reaching its full potential. The use of new digital technologies in this health sector responds to positive challenges in terms of organizational and educational efficiency; this requires the coordination of all stakeholders. The cardiology department -B - is a space conducive to the implementation of new digital technologies.
导读:我们生活在卫生部门信息技术(IT)创新的时代,这导致了新的组织模式的挪用,这正在深刻地改变医学实践。我们的研究旨在确定新数字技术在摩洛哥卫生系统中的挑战,以Ibn Sina大学医院中心的心脏病科- B为例。材料与方法:本研究是一项单中心观察性描述性分析研究,于2022年9月1日起在心内科B级开展,为期6个月。使用服务内部的数字设备,以纸质形式向工作人员所属的医生或正在进行实习的医生分发调查表。结果:共收集问卷31份,参与率78%;被调查者的年龄在21 - 55岁之间,平均年龄为30.3±8.71岁,女性占67.7%,我们样本中几乎一半的卫生专业人员(42%)是居民。部署最多的数字设备是医院信息系统(HIS),占80.6%;93.5%的受访者指出,节省时间是远程医疗的优势之一,71%的受访者肯定,可以更好地监测位于偏远地区的患者,以避免放弃护理。74.2%的受访者认为技术问题是部署远程程序的障碍;相比之下,诊断不明确的比例为22.2%;64.5%的受访者指出,培训将是将更多远程活动纳入其实践的主要杠杆,54.5%的受访者赞成调整时间段。结论:尽管存在阻碍数字化转型充分发挥其潜力的障碍,但受访者认为这些数字化工具的好处很多。在这一卫生部门使用新的数字技术应对了组织和教育效率方面的积极挑战;这需要所有利益攸关方的协调。心内科- b -是一个有利于实施新型数字技术的空间。
{"title":"[The challenges of new digital technologies on the Moroccan health system : Case of the cardiology departement -B- University Hospital Center Ibn Sina Rabat].","authors":"Kaoutar Chafiq, Kaoutar Dib, Ahmed Zahidi, Mohamed Cherti, Anass Doukkali, Kaoutar El Menzhi","doi":"10.1016/j.ancard.2024.101858","DOIUrl":"https://doi.org/10.1016/j.ancard.2024.101858","url":null,"abstract":"<p><strong>Introduction: </strong>We live in the era of information technology (IT) innovations in the health sector, this has led to the appropriation of new organizational models which are profoundly changing the practice of medicine. Our study aims to determine the challenges of new digital technologies in the Moroccan health system, the case of the cardiology department - B - of the Ibn Sina University Hospital Center.</p><p><strong>Materials and methods: </strong>This is a single-center observational descriptive-analytical study carried out at the level of the cardiology department - B- for 6 months, from September 1, 2022. Questionnaires were distributed in paper form to staff-affiliated medical doctor or carrying out their internships, using a digital device within the service.</p><p><strong>Results: </strong>Thirty-one (31) responses were collected, with a participation rate of 78%; the age of the respondents varies between 21 to 55 years with an average of 30.3± 8.71 years with a female predominance of 67.7% and almost half of the health professionals in our sample 42% were residents. The most deployed digital device is the Hospital Information System (HIS) in 80.6%; 93.5% of respondents noted that saving of time is one of the advantages of telemedicine and 71% of respondents who affirmed that the better monitoring of patients located in isolated areas in order to avoid forgoing care. 74.2% of respondents considered that technical problems constituted an obstacle to the deployment of remote procedures; compared to 22.2% for a weak diagnosis; 64.5% of respondents noted that training would be a major lever for integrating more remote activities into their practices and 54.5% of respondents are in favor of adapted time slots.</p><p><strong>Conclusion: </strong>The benefits perceived by respondents of these digital tools are numerous, although there are obstacles preventing digital transformation from reaching its full potential. The use of new digital technologies in this health sector responds to positive challenges in terms of organizational and educational efficiency; this requires the coordination of all stakeholders. The cardiology department -B - is a space conducive to the implementation of new digital technologies.</p>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"101858"},"PeriodicalIF":0.3,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Case report: We report the case of a 63-year-old patient who underwent aortic valve replacement with a biological valve for a bicuspid aortic stenosis, and LIMA-IVA single-bypass surgery. Two weeks later, he presented with Enterococcus faecillis bacteremia, attributed to left pyelonephritis and successfully treated with Amoxicillin. Two months after his surgery, he had a new bacteremia due to Enterococcus faecalis and we discovered a pseudo-aneurysm of the mitro-aortic trigone. Our patient is treated medically at first, before benefiting from the "Hemi-Commando" procedure.
Discussion: The mitro-aortic trigone is a fibrous area, located between the left half of the noncoronary cusp and the left coronary cusp of the aortic valve and the anterior leaflet of the mitral valve [1]. This area, important in the maintenance of mitral and aortic functions, [ii] is poorly vascularized and therefore very susceptible to infections and trauma [2]. Erosion of the aortic ring leads to the formation of a subvalvular abcess, secondarily detergated en then leads to the destruction of the trigone.
Conclusions: Pseudoaneurysm is a rare complication of aortic valve surgery and endocarditis. Given the risk of rupture, early surgery is recommended.
{"title":"[Pseudoaneurysm of the mitro-aortic trigone: Clinical case and literature review].","authors":"Hennebicq Sophie, Joly Emmanuel, Haberman David, Unger Philippe, De Cannière Didier, Leone Attilio","doi":"10.1016/j.ancard.2024.101853","DOIUrl":"https://doi.org/10.1016/j.ancard.2024.101853","url":null,"abstract":"<p><strong>Case report: </strong>We report the case of a 63-year-old patient who underwent aortic valve replacement with a biological valve for a bicuspid aortic stenosis, and LIMA-IVA single-bypass surgery. Two weeks later, he presented with Enterococcus faecillis bacteremia, attributed to left pyelonephritis and successfully treated with Amoxicillin. Two months after his surgery, he had a new bacteremia due to Enterococcus faecalis and we discovered a pseudo-aneurysm of the mitro-aortic trigone. Our patient is treated medically at first, before benefiting from the \"Hemi-Commando\" procedure.</p><p><strong>Discussion: </strong>The mitro-aortic trigone is a fibrous area, located between the left half of the noncoronary cusp and the left coronary cusp of the aortic valve and the anterior leaflet of the mitral valve [1]. This area, important in the maintenance of mitral and aortic functions, [ii] is poorly vascularized and therefore very susceptible to infections and trauma [2]. Erosion of the aortic ring leads to the formation of a subvalvular abcess, secondarily detergated en then leads to the destruction of the trigone.</p><p><strong>Conclusions: </strong>Pseudoaneurysm is a rare complication of aortic valve surgery and endocarditis. Given the risk of rupture, early surgery is recommended.</p>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"101853"},"PeriodicalIF":0.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
<p><strong>Introduction: </strong>The use of medicinal plants in Algeria is an ancestral practice that remains relevant today. The population relies on plants to treat various diseases and everyday ailments, which can be dangerous, especially when taking medication [1,2]. The interaction between plants and medication can lead to a modification of the plasma concentrations of the latter, which can impact its therapeutic effectiveness and be responsible for toxicity or therapeutic failure [1,2]. The interaction can also be pharmacodynamic, resulting in the potentiation of the effect or its antagonism. The risk is even higher when the medication has a narrow therapeutic range or presents high inter- or intra-individual variability, such as with vitamin K antagonist anticoagulants.</p><p><strong>Clinical case: </strong>We report the case of patient B.Z., aged 77, who is suffering from complete atrial fibrillation (ACFA). The patient has been under antivitamin K (AVK) treatment with acenocoumarol for 8 years and has been followed at the central laboratory of Didouche Mourad Hospital since August 2019. The patient has been stable with an INR within the therapeutic target range of 2-3 for 4 years. She is compliant and adheres to the dietary regimen. The dosage of acenocoumarol is alternated between 1/2 tablet and 1/4 tablet. On September 6, 2023, during a routine check-up, the patient's INR was 6.42, and the PT was 17.9%. The recommendation was to stop AVK and perform a control the following day. The interview revealed that the patient had started taking an infusion of oregano (Origanum vulgare), and occasionally verbena, at a rate of one 200 ml cup per day for a week. On September 7, 2023, the INR decreased to 3.80 and the PT to 26.9%, so the recommendation was to resume AVK at a dosage of 1/4 tablet to 1/2 tablet, with discontinuation of the herbal tea intake and an INR check after 72 hours. On the fourth day after resuming the anticoagulant, the INR was 2.5. Despite being informed of the risk of interaction, the patient resumed taking the freshly picked oregano herbal tea from her garden. Given the patient's determination to continue her infusion, the recommendation was made to limit her intake, to prepare much more diluted infusions, and to reduce the dose of acenocoumarol to 1/4 tablet; this allowed the stabilization of the patient's INR. The last check-up was performed on April 7, 2024, with an INR value of 2.3.</p><p><strong>Results: </strong>Oregano, a plant from the Lamiaceae family, is used in herbal tea to treat a wide range of diseases, including joint pain, respiratory conditions, and digestive disorders. Similarly, verbena is also used to combat sleep disorders [2-4]. Origanum and verbena are both plants rich in polyphenols, as well as tannins and flavonoids. These substances are inhibitors of CYP 450, particularly CYP 2C9 and CYP 3A4, which are responsible for the metabolism of many drugs, including painkillers, antihypertensives, central
{"title":"[Origanum vulgare and hemorrhagic risk, about a case].","authors":"Imene Beghriche, Abdelaali Belhachem, Imene Hamidene, Allaoua Hicham Fendri","doi":"10.1016/j.ancard.2024.101856","DOIUrl":"https://doi.org/10.1016/j.ancard.2024.101856","url":null,"abstract":"<p><strong>Introduction: </strong>The use of medicinal plants in Algeria is an ancestral practice that remains relevant today. The population relies on plants to treat various diseases and everyday ailments, which can be dangerous, especially when taking medication [1,2]. The interaction between plants and medication can lead to a modification of the plasma concentrations of the latter, which can impact its therapeutic effectiveness and be responsible for toxicity or therapeutic failure [1,2]. The interaction can also be pharmacodynamic, resulting in the potentiation of the effect or its antagonism. The risk is even higher when the medication has a narrow therapeutic range or presents high inter- or intra-individual variability, such as with vitamin K antagonist anticoagulants.</p><p><strong>Clinical case: </strong>We report the case of patient B.Z., aged 77, who is suffering from complete atrial fibrillation (ACFA). The patient has been under antivitamin K (AVK) treatment with acenocoumarol for 8 years and has been followed at the central laboratory of Didouche Mourad Hospital since August 2019. The patient has been stable with an INR within the therapeutic target range of 2-3 for 4 years. She is compliant and adheres to the dietary regimen. The dosage of acenocoumarol is alternated between 1/2 tablet and 1/4 tablet. On September 6, 2023, during a routine check-up, the patient's INR was 6.42, and the PT was 17.9%. The recommendation was to stop AVK and perform a control the following day. The interview revealed that the patient had started taking an infusion of oregano (Origanum vulgare), and occasionally verbena, at a rate of one 200 ml cup per day for a week. On September 7, 2023, the INR decreased to 3.80 and the PT to 26.9%, so the recommendation was to resume AVK at a dosage of 1/4 tablet to 1/2 tablet, with discontinuation of the herbal tea intake and an INR check after 72 hours. On the fourth day after resuming the anticoagulant, the INR was 2.5. Despite being informed of the risk of interaction, the patient resumed taking the freshly picked oregano herbal tea from her garden. Given the patient's determination to continue her infusion, the recommendation was made to limit her intake, to prepare much more diluted infusions, and to reduce the dose of acenocoumarol to 1/4 tablet; this allowed the stabilization of the patient's INR. The last check-up was performed on April 7, 2024, with an INR value of 2.3.</p><p><strong>Results: </strong>Oregano, a plant from the Lamiaceae family, is used in herbal tea to treat a wide range of diseases, including joint pain, respiratory conditions, and digestive disorders. Similarly, verbena is also used to combat sleep disorders [2-4]. Origanum and verbena are both plants rich in polyphenols, as well as tannins and flavonoids. These substances are inhibitors of CYP 450, particularly CYP 2C9 and CYP 3A4, which are responsible for the metabolism of many drugs, including painkillers, antihypertensives, central","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"101856"},"PeriodicalIF":0.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-09DOI: 10.1016/j.ancard.2024.101860
Yassine Rabab, Ndao Serigne Cheikh Tidiane, Ka Mame Madjiguene, Mboup Waly Niang, Fall Aissatou, Dia Khadidiatou, Mboup Mouhamed Chérif
Introduction: Heart failure is a major public health problem because of the number and duration of hospitalizations. Patients with heart failure may have mixed etiologies that are not mutually exclusive, and etiologies vary between high-income and developing countries. The aim of our work was to study the contribution of coronary angiography in the etiological investigation of heart failure with impaired LVEF in the cardiology department of HPD.
Methodology: This was a descriptive and analytical cross-sectional study with retrospective data collection on 103 patients hospitalized in the cardiology department of DAKAR's Hospital Principal presenting with heart failure with impaired LVEF and who underwent coronary angiography from January 2019 to December 2022.
Results: Our study included 103 patients with a clear male predominance 79.6% and a sex ratio of 3.7. Their mean age was 64±13.5 years. Diabetes was prevalent at 24.3% (p=0.033). All patients had impaired segmental and/or global left ventricular kinetics. Mean ejection fraction was 28.1±6.8. The right radial route was predominantly used 83.7% of the time, and there were no procedural incidents or accidents. Diabetes was significantly associated with coronary involvement (p=0.033). Coronary angiography was normal in 37.8% of patients and showed tri-truncular lesions in 19.4% of patients and bi-truncular lesions in 17.4%. We found 91 significant lesion and 67 non-significant lesion. A total of 41 patients had ischemic heart disease, equivalent to 39.8%.
Conclusion: Our study shows that ischemic heart disease plays an important role in the etiology of heart failure with impaired LVEF, and that coronary angiography should be performed routinely.
{"title":"[Coronarography and etiologies of heart failure with impaired left ventricular ejection fraction in Senegal].","authors":"Yassine Rabab, Ndao Serigne Cheikh Tidiane, Ka Mame Madjiguene, Mboup Waly Niang, Fall Aissatou, Dia Khadidiatou, Mboup Mouhamed Chérif","doi":"10.1016/j.ancard.2024.101860","DOIUrl":"https://doi.org/10.1016/j.ancard.2024.101860","url":null,"abstract":"<p><strong>Introduction: </strong>Heart failure is a major public health problem because of the number and duration of hospitalizations. Patients with heart failure may have mixed etiologies that are not mutually exclusive, and etiologies vary between high-income and developing countries. The aim of our work was to study the contribution of coronary angiography in the etiological investigation of heart failure with impaired LVEF in the cardiology department of HPD.</p><p><strong>Methodology: </strong>This was a descriptive and analytical cross-sectional study with retrospective data collection on 103 patients hospitalized in the cardiology department of DAKAR's Hospital Principal presenting with heart failure with impaired LVEF and who underwent coronary angiography from January 2019 to December 2022.</p><p><strong>Results: </strong>Our study included 103 patients with a clear male predominance 79.6% and a sex ratio of 3.7. Their mean age was 64±13.5 years. Diabetes was prevalent at 24.3% (p=0.033). All patients had impaired segmental and/or global left ventricular kinetics. Mean ejection fraction was 28.1±6.8. The right radial route was predominantly used 83.7% of the time, and there were no procedural incidents or accidents. Diabetes was significantly associated with coronary involvement (p=0.033). Coronary angiography was normal in 37.8% of patients and showed tri-truncular lesions in 19.4% of patients and bi-truncular lesions in 17.4%. We found 91 significant lesion and 67 non-significant lesion. A total of 41 patients had ischemic heart disease, equivalent to 39.8%.</p><p><strong>Conclusion: </strong>Our study shows that ischemic heart disease plays an important role in the etiology of heart failure with impaired LVEF, and that coronary angiography should be performed routinely.</p>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"101860"},"PeriodicalIF":0.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-09DOI: 10.1016/j.ancard.2024.101861
X Humbert, E Touze, J Le Bas, L Schonbrodt, P-A Couette, S De Jaegher, A Pithon, J Alexandre, P-E Puddu
{"title":"Corrigendum to “Office white-coat effect tail: A useful tool in family practice?” [Annales de cardiologie et d'angéiologie 73 (2024) 101733].","authors":"X Humbert, E Touze, J Le Bas, L Schonbrodt, P-A Couette, S De Jaegher, A Pithon, J Alexandre, P-E Puddu","doi":"10.1016/j.ancard.2024.101861","DOIUrl":"https://doi.org/10.1016/j.ancard.2024.101861","url":null,"abstract":"","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 1","pages":"101861"},"PeriodicalIF":0.3,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142963564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-20DOI: 10.1016/S0003-3928(24)00124-0
{"title":"Sommaire","authors":"","doi":"10.1016/S0003-3928(24)00124-0","DOIUrl":"10.1016/S0003-3928(24)00124-0","url":null,"abstract":"","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"73 6","pages":"Article 101846"},"PeriodicalIF":0.3,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}