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Sommaire 摘要
IF 0.3 Q4 Medicine Pub Date : 2025-09-01 Epub Date: 2025-09-04 DOI: 10.1016/S0003-3928(25)00085-X
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引用次数: 0
[Coronary revascularization in diabetic patient: which approach to choose?] 糖尿病患者冠状动脉血运重建术:选择哪种方法?
IF 0.3 Q4 Medicine Pub Date : 2025-09-01 Epub Date: 2025-08-08 DOI: 10.1016/j.ancard.2025.101918
Mehdi Benamer, Patrick Henry, Jean Guillaume Dillinger, Antoine Lequipar, Théo Pezel, Alexandre Lafont, Emmanuel Gall

Diabetes constitutes a major risk factor for coronary artery disease, with often diffuse, calcified, and complex lesions, making the revascularization strategy particularly challenging. We report two clinical cases illustrating contrasting approaches in diabetic patients presenting with multivessel coronary disease. The first case involves a complex coronary angioplasty in the setting of acute coronary syndrome, guided by intracoronary imaging, highlighting the value of this modality in ostial left main lesions. The second case describes surgical revascularization in a stable patient with extensive coronary artery disease and left ventricular dysfunction, demonstrating the superiority of coronary artery bypass grafting in this context. These observations illustrate the importance of a personalized and multidisciplinary approach, based on current guidelines and the patient's anatomical and clinical characteristics. The advent of modern revascularization techniques and the anticipated results of the ANDAMAN study could soon redefine the standards of care for these high-risk patients.

糖尿病是冠状动脉疾病的主要危险因素,常伴有弥漫性、钙化和复杂病变,使得血管重建策略特别具有挑战性。我们报告两个临床病例,说明不同的方法在糖尿病患者呈现多支冠状动脉疾病。第一个病例涉及急性冠状动脉综合征背景下的复杂冠状动脉成形术,在冠状动脉内成像的指导下,突出了这种模式在口左主干病变中的价值。第二个病例描述了一个稳定的伴有广泛冠状动脉疾病和左心室功能障碍的患者的手术血运重建术,证明了冠状动脉旁路移植术在这种情况下的优越性。这些观察结果说明了基于当前指南和患者解剖和临床特征的个性化和多学科方法的重要性。现代血运重建技术的出现和ANDAMAN研究的预期结果可能很快重新定义这些高危患者的护理标准。
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引用次数: 0
Séniors et lésions coronaires calcifiées 老年和冠状动脉钙化损伤
IF 0.3 Q4 Medicine Pub Date : 2025-09-01 Epub Date: 2025-08-20 DOI: 10.1016/j.ancard.2025.101926
Ikram El marzouki , Jacques Monsegu
Coronary artery calcification is highly prevalent in elderly patients and poses significant challenges during percutaneous coronary intervention (PCI).
We report the case of an 86-year-old man admitted for ST-elevation myocardial infarction. Coronary angiography revealed triple-vessel disease with an acute coronary artery occlusion, a long, heavily calcified proximal-to-mid left anterior descending artery stenosis, and a severely calcified proximal circumflex lesion. PCI revascularization was performed in 3 steps: primary PCI of the right coronary artery initially, then 3 days after, PCI of the circumflex artery using rotational atherectomy, scoring balloon dilation, and intravascular lithotripsy. Then, at Day 15, PCI of the left anterior descending artery with orbital atherectomy finished complete revascularization.
This case underscores the importance of a comprehensive geriatric assessment—particularly frailty and physiological age—before selecting a revascularization strategy requiring the use of specific tools as advanced plaque-modification techniques and intravascular imaging, without any restriction according to age.
冠状动脉钙化在老年患者中非常普遍,对经皮冠状动脉介入治疗(PCI)提出了重大挑战。我们报告的情况下,86岁的男子承认st段抬高心肌梗死。冠状动脉造影显示三支血管病变,包括急性冠状动脉闭塞,左前降支近端至中端长且严重钙化狭窄,以及严重钙化的近端旋支病变。PCI血运重建术分3步进行:最初对右冠状动脉进行初级PCI,然后在3天后,采用旋转动脉粥样硬化切除术、记分球囊扩张和血管内碎石对旋支动脉进行PCI。然后,在第15天,左前降支PCI并眼眶动脉粥样硬化切除术完成完全血运重建。该病例强调了全面的老年评估的重要性,特别是虚弱和生理年龄,在选择血管重建策略之前,需要使用特定的工具,如先进的斑块修饰技术和血管内成像,而不受年龄的限制。
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引用次数: 0
[Medicine for all, special attention for everyone]. [人人有药,人人有心]。
IF 0.3 Q4 Medicine Pub Date : 2025-09-01 Epub Date: 2025-08-09 DOI: 10.1016/j.ancard.2025.101923
Orianne Weizman, Mehdi Benamer, Hakim Benamer
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引用次数: 0
Management of Acenocoumarol in Tunisian elderly population : Risk factors of overdose and bleeding 突尼斯老年人口中的醋硝香豆素管理 :用药过量和出血的风险因素
IF 0.3 Q4 Medicine Pub Date : 2025-06-01 Epub Date: 2025-04-11 DOI: 10.1016/j.ancard.2025.101894
Ines Kechaou , Mohamed Salah Hamdi , Asma Tekaya , Amira Taouay , Eya Cherif , Lamia Ben Hassine

Introduction

Anticoagulant therapy, often required in the elderly, is not without risk. This study aims to investigate the particularities of the use of anticoagulants in the elderly during hospital stay, along with the factors associated with bleeding and overdose.

Results

There were 55 women and 45 men (sex ratio: 0.81), with a mean age of 75.7 ± 6.9 years. The indications for anticoagulant treatment were venous thromboembolism (VTE) (92%) and atrial fibrillation (AF) (8%).
The average duration of treatment with acenocoumarol was 17.22 days ± 7.9. The dose of acenocoumarol initiation was 1 mg in 85% of patients and 2 mg in 15%.
INR < 2 was observed in 15% of patients. INR in the target area was obtained in 47% of patients with a mean dose of 2.33 mg of acenocoumarol. An overdose of acenocoumarol was noted in 38% of patients: average INR at 4.7. Seven patients had bleeding events. An overdose was reported in 4 of them.
Fever, infection, inflammatory syndrome, hypoalbuminemia, hypoprotidemia, and malnutrition were associated with a greater risk of overdose in our patients. Gastroduodenal ulcer disease, past medical history of gastrointestinal bleeding and renal failure were risk factors for bleeding in our patients.

Conclusion

The use of anticoagulants in the elderly requires a comprehensive assessment, including comorbidities, geriatric settings, and social environment.
抗凝治疗常用于老年人,但并非没有风险。本研究旨在探讨老年人住院期间抗凝血剂使用的特殊性,以及与出血和用药过量相关的因素。结果女性55例,男性45例(性别比0.81),平均年龄75.7±6.9岁。抗凝治疗的适应症为静脉血栓栓塞(VTE)(92%)和心房颤动(AF)(8%)。阿塞诺古美尔治疗的平均持续时间为17.22天±7.9天。阿塞诺古豆素起始剂量为85%的患者1mg, 15%的患者2mg。INR & lt;在15%的患者中观察到2。47%的患者平均剂量为2.33 mg阿塞诺古玛罗,靶区获得INR。38%的患者发现阿塞诺古豆醇过量:平均INR为4.7。7例患者出现出血事件。其中4人被报告服药过量。发热、感染、炎症综合征、低白蛋白血症、低蛋白质血症和营养不良与我们的患者用药过量风险增加有关。胃十二指肠溃疡、既往消化道出血和肾功能衰竭是本组患者出血的危险因素。结论老年人抗凝血药物的使用需要综合评估,包括合并症、老年背景和社会环境。
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引用次数: 0
Sommaire 摘要
IF 0.3 Q4 Medicine Pub Date : 2025-06-01 Epub Date: 2025-05-29 DOI: 10.1016/S0003-3928(25)00049-6
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引用次数: 0
Le Pontage Coronarien chez le Sujet de Moins de 45 ans : Profil caractéristique et résultat à long terme 45岁以下患者的冠状动脉搭桥:特征特征和长期结果
IF 0.3 Q4 Medicine Pub Date : 2025-06-01 Epub Date: 2025-05-08 DOI: 10.1016/j.ancard.2025.101900
Yassin El Mourabit , Mohammed Tribak , Hasna Leghlimi , Wafae El Amraoui , Mehdi Laaroussi , Abderahmane El Bakkali , Lahcen Mermade , Said Moughil
<div><h3>Introduction</h3><div>La coronaropathie chez le sujet jeune présente des particularités influençant la prise en charge, faisant du pontage coronarien le traitement de référence, avec un intérêt notable dans ce contexte.</div></div><div><h3>But</h3><div>Le but de notre étude est de caractériser le profil des patients et d'évaluer les résultats à court et à long terme du pontage coronarien chez les sujets de moins de 45 ans.</div></div><div><h3>Méthodes</h3><div>Entre mai 1995 et décembre 2022, 130 patients jeunes ont bénéficié d'un pontage coronarien. Les variables analysées comprenaient la mortalité hospitalière, la morbidité postopératoire, la mortalité globale et cardiovasculaire, ainsi que l'occurrence d'événements cardiovasculaires majeurs. De plus, la qualité de vie des patients et leur adhésion au traitement ont également été démontrées. Le suivi moyen des patients était de 11 ± 2 ans.</div></div><div><h3>Résultats</h3><div>La mortalité hospitalière était de 1,53 %. La morbidité postopératoire était de 24,61 %. La durée moyenne du séjour hospitalier était de 11±8 jours. La survie globale à 1, 5 et 10 ans était respectivement de 98 %, 95 % et 89 %. L'absence d'événements cardiovasculaires majeurs dans notre série était de 95,31 % à 1 an, 86,71 % à 5 ans et 82,03 % à 10 ans. Après un suivi moyen de 11 ± 2 ans (2-28 ans), 75,5 % des patients diabétiques ont un diabète contrôlé et 82,7 % ont arrêté de fumer, alors que la dyspnée d'effort et l'angor persistent respectivement chez 36 % et 18 % des patients.</div></div><div><h3>Conclusion</h3><div>Nos résultats démontrent que le pontage coronaire donne aux patients jeunes une morbi-mortalité hospitalière très admissible et une survie à long terme excellente, avec amélioration de la qualité de vie.</div></div><div><h3>Introduction</h3><div>Coronary artery disease in young patients presents particularities that influence management, making coronary artery bypass grafting (CABG) the treatment of choice, with significant relevance in this context.</div></div><div><h3>Objective</h3><div>The aim of our study is to characterize the profile of patients and evaluate the short- and long-term outcomes of coronary artery bypass grafting in patients under 45 years of age.</div></div><div><h3>Methods</h3><div>Between May 1995 and December 2022, 130 young patients underwent coronary artery bypass grafting. The variables analyzed included hospital mortality, postoperative morbidity, overall and cardiovascular mortality, as well as the occurrence of major cardiovascular events. Additionally, patients' quality of life and treatment adherence were also assessed. The mean follow-up period for patients was 11 ± 2 years.</div></div><div><h3>Results</h3><div>Hospital mortality was 1.53%. Postoperative morbidity was 24.61%. The mean length of hospital stay was 11±8 days. The overall survival at 1, 5, and 10 years was 98%, 95%, and 89%, respectively. The absence of major cardiovascular events in our series was 95
年轻患者的冠状动脉疾病表现出影响治疗的特点,使冠状动脉搭桥成为参考治疗,在这方面具有显著的意义。本研究的目的是描述45岁以下患者的冠状动脉搭桥手术的短期和长期结果。方法1995年5月至2022年12月期间,130名年轻患者接受了冠状动脉搭桥手术。分析的变量包括医院死亡率、术后发病率、总死亡率和心血管死亡率以及重大心血管事件的发生率。此外,患者的生活质量和对治疗的依从性也得到了证明。患者平均随访时间为11±2年,住院死亡率为1.53%。术后患病率为24.61%。平均住院时间为11±8天。1岁、5岁和10岁的总存活率分别为98%、95%和89%。缺乏主要心血管事件的系列中,我们为95.31至一岁,86.71 10岁至5岁和82.03。经过监测平均11±2岁(工具),75.5%的糖尿病患者有糖尿病控制和82.7%戒烟了,而用力呼吸困难和l’angor仍分别为36%和18%的病人。结论:我们的研究结果表明,冠状动脉搭桥手术为年轻患者提供了高度可接受的住院发病率和死亡率,并提供了良好的长期存活率,提高了生活质量。介绍冠状动脉疾病在年轻患者中表现出影响管理的特殊性,使冠状动脉搭桥术(CABG)成为治疗的选择,在这一背景下具有重要意义。目的本研究的目的是表征患者概况,并评估45岁以下患者冠状动脉搭桥术的短期和长期结果。方法:1995年5月至2022年12月期间,130名年轻患者进行冠状动脉搭桥移植。分析的变量包括医院死亡率、术后发病率、总体和心血管死亡率以及主要心血管事件的发生率。此外,还对患者的生活质量和治疗依从性进行了评估。患者的平均随访期为11±2年。结果医院死亡率为1.53%。术后发病率为24.61%。平均住院时间为11±8天。1岁、5岁和10岁的总生存率分别为98%、95%和89%。在我们的系列中,1年无重大心血管事件95.31%,5年86.71%,10年82.03%。经过11±2年(2-28年)的平均随访,75.5%的糖尿病患者控制了糖尿病,82.7%的患者戒烟,而运动障碍和心绞痛分别在36%和18%的患者中持续存在。结论我们的结果表明,年轻患者的冠状动脉搭桥术与非常可接受的医院发病率和死亡率以及良好的长期生存率以及生活质量的提高有关。
{"title":"Le Pontage Coronarien chez le Sujet de Moins de 45 ans : Profil caractéristique et résultat à long terme","authors":"Yassin El Mourabit ,&nbsp;Mohammed Tribak ,&nbsp;Hasna Leghlimi ,&nbsp;Wafae El Amraoui ,&nbsp;Mehdi Laaroussi ,&nbsp;Abderahmane El Bakkali ,&nbsp;Lahcen Mermade ,&nbsp;Said Moughil","doi":"10.1016/j.ancard.2025.101900","DOIUrl":"10.1016/j.ancard.2025.101900","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Introduction&lt;/h3&gt;&lt;div&gt;La coronaropathie chez le sujet jeune présente des particularités influençant la prise en charge, faisant du pontage coronarien le traitement de référence, avec un intérêt notable dans ce contexte.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;But&lt;/h3&gt;&lt;div&gt;Le but de notre étude est de caractériser le profil des patients et d'évaluer les résultats à court et à long terme du pontage coronarien chez les sujets de moins de 45 ans.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Méthodes&lt;/h3&gt;&lt;div&gt;Entre mai 1995 et décembre 2022, 130 patients jeunes ont bénéficié d'un pontage coronarien. Les variables analysées comprenaient la mortalité hospitalière, la morbidité postopératoire, la mortalité globale et cardiovasculaire, ainsi que l'occurrence d'événements cardiovasculaires majeurs. De plus, la qualité de vie des patients et leur adhésion au traitement ont également été démontrées. Le suivi moyen des patients était de 11 ± 2 ans.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Résultats&lt;/h3&gt;&lt;div&gt;La mortalité hospitalière était de 1,53 %. La morbidité postopératoire était de 24,61 %. La durée moyenne du séjour hospitalier était de 11±8 jours. La survie globale à 1, 5 et 10 ans était respectivement de 98 %, 95 % et 89 %. L'absence d'événements cardiovasculaires majeurs dans notre série était de 95,31 % à 1 an, 86,71 % à 5 ans et 82,03 % à 10 ans. Après un suivi moyen de 11 ± 2 ans (2-28 ans), 75,5 % des patients diabétiques ont un diabète contrôlé et 82,7 % ont arrêté de fumer, alors que la dyspnée d'effort et l'angor persistent respectivement chez 36 % et 18 % des patients.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;Nos résultats démontrent que le pontage coronaire donne aux patients jeunes une morbi-mortalité hospitalière très admissible et une survie à long terme excellente, avec amélioration de la qualité de vie.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Introduction&lt;/h3&gt;&lt;div&gt;Coronary artery disease in young patients presents particularities that influence management, making coronary artery bypass grafting (CABG) the treatment of choice, with significant relevance in this context.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;The aim of our study is to characterize the profile of patients and evaluate the short- and long-term outcomes of coronary artery bypass grafting in patients under 45 years of age.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Between May 1995 and December 2022, 130 young patients underwent coronary artery bypass grafting. The variables analyzed included hospital mortality, postoperative morbidity, overall and cardiovascular mortality, as well as the occurrence of major cardiovascular events. Additionally, patients' quality of life and treatment adherence were also assessed. The mean follow-up period for patients was 11 ± 2 years.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Hospital mortality was 1.53%. Postoperative morbidity was 24.61%. The mean length of hospital stay was 11±8 days. The overall survival at 1, 5, and 10 years was 98%, 95%, and 89%, respectively. The absence of major cardiovascular events in our series was 95","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 3","pages":"Article 101900"},"PeriodicalIF":0.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143918051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hémoptysie révélatrice d'une agénésie de l'artère pulmonaire gauche : à propos d'un cas 左肺动脉变性血液病:关于一个病例
IF 0.3 Q4 Medicine Pub Date : 2025-06-01 Epub Date: 2025-04-11 DOI: 10.1016/j.ancard.2025.101895
Labied Mohamed, Bouzid Ismail, El Oualladi Feryal, Mountassir Chorouk, Lembarki Ghizlane, Sabiri Mouna, Lezar Samira
Unilateral agenesis of the pulmonary artery is a rare congenital malformation. Diagnosis is based on imaging due to the nonspecificity of clinical symptoms. Hemoptysis is among the rare manifestations of this malformation. Standard radiography provides relevant orientation elements; however, CT pulmonary angiography remains the reference examination for positive diagnosis. We report the case of a 47-year-old patient presenting with recurrent episodes of minimal hemoptysis occurring quietly. A CT pulmonary angiography was performed, revealing agenesis of the left pulmonary artery.
单侧肺动脉缺失是一种罕见的先天性畸形。由于临床症状无特异性,诊断主要依靠影像学检查。咯血是这种畸形的罕见表现之一。标准影像学检查可提供相关的定位要素;然而,CT 肺血管造影仍是阳性诊断的参考检查。我们报告了一例 47 岁患者的病例,该患者反复发作轻微咯血,且悄无声息。CT 肺血管造影显示左肺动脉发育不全。
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引用次数: 0
La santé mentale des auxiliaires médicaux en rythmologie interventionnelle 干预节律学医务助理的心理健康
IF 0.3 Q4 Medicine Pub Date : 2025-06-01 Epub Date: 2025-04-11 DOI: 10.1016/j.ancard.2025.101891
Carole Mette , Karine Petit , Laurent Fauchier
The mental health of allied professionals in interventional electrophysiology is an increasingly concerning topic given the emotional and physical demands inherent in their role, which deserves particular attention. This article examines the impact of stress, anxiety, and burnout on these healthcare professionals. To this end, an anonymous survey of allied professionals in interventional electrophysiology was conducted using a questionnaire via a dedicated survey platform over a period from October 17 to December 10, 2024. The data extracted and analyzed with the help of the platform revealed the following difficulties: lack of recognition, unsatisfactory working conditions, high workload, relational difficulties, and a lack of organization. This has resulted in an impact on the feelings of the allied professionals and especially on their work. In conclusion, this study reveals a generalized feeling of malaise among all allied professionals in interventional electrophysiology on a psychological, emotional, and physical level, as well as the importance of investing in the mental health of allied professionals for the improvement of the entire healthcare system.
介入电生理学专业人员的心理健康是一个越来越受关注的话题,因为他们的角色固有的情感和身体需求,这值得特别关注。本文研究了压力、焦虑和倦怠对这些医疗保健专业人员的影响。为此,在2024年10月17日至12月10日期间,通过专用调查平台使用问卷对介入电生理学相关专业人员进行了匿名调查。在平台的帮助下提取和分析的数据揭示了以下困难:缺乏认可,工作条件不理想,工作量大,关系困难,缺乏组织。这对专职人员的感情造成了影响,特别是对他们的工作造成了影响。综上所述,本研究揭示了介入电生理学专业人员在心理、情绪和身体层面上普遍存在的不适感,以及投资于专业人员心理健康对整个医疗保健系统改善的重要性。
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引用次数: 0
Réadaptation Cardiovasculaire au Centre Hospitalo-Universitaire de Conakry : Enquête auprès des Médecins 科纳克里大学医院心血管康复:对医生的调查
IF 0.3 Q4 Medicine Pub Date : 2025-06-01 Epub Date: 2025-05-06 DOI: 10.1016/j.ancard.2025.101901
Ibrahima Sory Sylla, Mamadou Barry, Abdoulaye Camara, Aïssatou Barry, Mamadou Bachir Bah, Ousmane Mamadama Camara, Alpha Koné, Ibrahima Sory Barry, Djibril Sylla, Elhadj Yaya Baldé, Mamadou Dadhi Baldé
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引用次数: 0
期刊
Annales de cardiologie et d'angeiologie
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