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The Distribution of Lifestyle Risk Factors Among Patients with Stroke in the Indian Setting: Systematic Review and Meta-Analysis. 印度中风患者的生活方式风险因素分布:系统回顾与元分析。
IF 1.8 Q4 NEUROSCIENCES Pub Date : 2023-01-01 Epub Date: 2022-08-08 DOI: 10.1177/09727531221115899
Biji P Varkey, Jaison Joseph, Abin Varghese, Suresh K Sharma, Elezebeth Mathews, Manju Dhandapani, Venkata Lakshmi Narasimha, Radha Kuttan, Saleena Shah, Surekha Dabla, Sivashanmugam Dhandapani

Background: The burden of stroke is increasing in India, but there is limited understanding of the distribution of reported risk factors in the Indian setting. It is vital to generate robust data on these modifiable risk factors to scale up appropriate strategies for the prevention of cerebrovascular diseases in this setting.

Summary: The objective of this study is to estimate the overall proportion of life style risk factors of patients with stroke in the Indian setting. We searched PubMed and Google Scholar and relevant studies published till February 2022 were included. The risk of bias assessment was considered for the study selection criterion in the meta-analysis. The publication bias was evaluated by funnel plots and Egger's test. We identified 61 studies in the systematic review and after quality assessment, 36 studies were included for meta-analysis. Random effect model was used due to the significant inconsistency among the included studies (I2 > 97%). The mean age of the participants was 53.84±9.3 years and patients with stroke were predominantly males (64%). Hypertension (56.69%; 95% CI: - 48.45 - 64.58), obesity (36.61%; 95% CI: - 19.31 - 58.23), dyslipidemia (30.6%; 95% CI: - 22 - 40.81) and diabetes mellitus (23.8%; 95% CI: - 18.79 - 29.83) are the leading intermediate conditions associated with stroke. The Physical inactivity - 29.9% (95% CI: - 22.9 - 37.1), history of tobacco use (28.59 %; 95% CI: - 22.22 - 32.94) and alcohol use (28.15 %; 95% CI: - 20.49 - 37.33) were reported as the behavioral risk factors for stroke in this setting.

Key messages: The current meta-analysis provides robust estimates of the life style related risk-factor of stroke in India based on the observational studies conducted from 1994 to 2019. Estimating the pooled analysis of stroke risk factors is crucial to predict the imposed burden of the illness and ascertain the treatment and prevention strategies for controlling the modifiable risk factors in this setting.

背景:印度的中风负担日益加重,但人们对印度环境中报告的风险因素分布了解有限。摘要:本研究的目的是估计印度中风患者生活方式风险因素的总体比例。我们检索了 PubMed 和 Google Scholar,纳入了截至 2022 年 2 月发表的相关研究。荟萃分析中的研究选择标准考虑了偏倚风险评估。发表偏倚通过漏斗图和 Egger 检验进行评估。我们在系统综述中确定了 61 项研究,经过质量评估后,纳入了 36 项研究进行荟萃分析。由于纳入的研究之间存在显著的不一致性(I2>97%),因此采用了随机效应模型。参与者的平均年龄为(53.84±9.3)岁,脑卒中患者主要为男性(64%)。高血压(56.69%;95% CI:- 48.45 - 64.58)、肥胖(36.61%;95% CI:- 19.31 - 58.23)、血脂异常(30.6%;95% CI:- 22 - 40.81)和糖尿病(23.8%;95% CI:- 18.79 - 29.83)是与中风相关的主要中间疾病。据报道,在这种情况下,缺乏运动(29.9%;95% CI:- 22.9 - 37.1)、吸烟史(28.59%;95% CI:- 22.22 - 32.94)和饮酒(28.15%;95% CI:- 20.49 - 37.33)是中风的行为风险因素:当前的荟萃分析基于 1994 年至 2019 年开展的观察性研究,对印度与生活方式相关的中风风险因素进行了可靠的估计。估计中风风险因素的汇总分析对于预测该疾病所带来的负担以及确定在这种情况下控制可改变风险因素的治疗和预防策略至关重要。
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引用次数: 0
Minority Stress in Emotion Suppression and Mental Distress Among Sexual and Gender Minorities: A Systematic Review. 性少数群体和性别少数群体在情绪压抑和精神痛苦方面的应激:系统回顾。
IF 1.5 Q4 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.1177/09727531221120356
Akanksha Singh, Anu Dandona, Vibha Sharma, S Z H Zaidi

Background: The existing structural framework of defining gender and sexuality based on heteronormative ideology led to the succession of the notions of stigma, prejudice, and hate towards the sexual and gender minority population. The presence of strong scientific evidence for the negative consequences of discriminatory and violent events has directed the association with mental and emotional distress. This study aims to comprehend the role of minority stress in emotional regulation and suppression among the sexual minority population globally using systematic review of literature through elaborate Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines.

Summary: The analyses of the sorted literature premised on the PRISMA guidelines revealed that minority stress mediates the emotion regulation processes among the individuals who witness continuous episodes of discrimination and violence leading to emotional dysregulation and emotion suppression. Studies also reported the dominance of various health-risk behaviors such as alcohol addiction, drug abuse, and other forms of intoxication among sexual minority individuals. Increased instances of anxiety, stress, depression, and suicidal ideations were prominent in the findings of the empirical research suggesting an intricate role of minority stress in advancing the faulty emotion suppression and mental health concerns among the sexual and gender minority population.

Key message: Minority stressors among sexual and gender minority individuals mediate emotion suppression and mental distress.

背景:基于异性恋规范意识形态的现有性别和性定义结构框架导致了对性和性别少数群体的污名化、偏见和仇恨观念的继承。有强有力的科学证据表明,歧视和暴力事件的负面后果与精神和情感痛苦有关。本研究旨在通过系统回顾文献,通过精心设计的系统回顾和荟萃分析(PRISMA)指南,了解全球性少数人群中少数群体压力在情绪调节和抑制中的作用。摘要:基于PRISMA指南的文献整理分析表明,少数民族应激在持续遭受歧视和暴力事件导致情绪失调和情绪抑制的个体中起调节作用。研究还报告,在性少数群体中,酗酒、滥用药物和其他形式的中毒等各种健康风险行为占主导地位。实证研究发现,焦虑、压力、抑郁和自杀意念的增加是突出的,这表明少数民族压力在促进性和性别少数群体的错误情绪抑制和心理健康问题方面发挥了复杂的作用。关键信息:性少数和性别少数个体的少数压力源介导情绪抑制和精神痛苦。
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引用次数: 1
Future of Monoclonal Antibody Therapy in Parkinson's Disease. 单克隆抗体治疗帕金森病的未来
IF 1.5 Q4 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.1177/09727531221136349
Sanjeev Kharel, Rajeev Ojha
Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons AttributionNonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-Commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https:// us.sagepub.com/en-us/nam/open-access-at-sage). Commentary
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引用次数: 1
Positive Psychological Changes at High Altitude Shown by the Low Landers after the Yoga Intervention-Sudarshan Kriya Yoga (SKY). 瑜伽干预后低地人在高海拔的积极心理变化——苏达山克里亚瑜伽(SKY)。
IF 1.5 Q4 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.1177/09727531221117637
Sheetal J Gupta, Balaram Pradhan, Disha Bhanushali, Rishi Nityapragya Nitin Limaye

Background: Immediate assent to high altitude affects the cognitive performance and mood of an individual, which is followed by depression and anxiety. It also affects the sleep quality, general health, and happiness quotient of an individual. Sudarshan Kriya Yoga (SKY) is a cyclical breathing technique, which has been proven successful in managing stress, depression, anxiety, and helps in the improvement of sleep quality.

Purpose: The current study was to understand the role of SKY meditation on psychological parameters, happiness quotient of low landers at high altitude (Leh).

Methods: It is a two-armed pre-post study with experimental and control group both are lowlanders, and their psychological parameters are being assessed when they immediately assent to high altitude (Leh). There are two groups experimental group (SKY) was from AOL SKY-AMP and has prior SKY meditation experience. The control group does not have any yoga or meditation experience. SKY-AMP is a 4 days protocol done at high altitude by the SKY group. Both groups reach Leh through air mode transportation.

Results: Oxford Happiness Questionnaire (OHQ) showed a significant result in the SKY group with P ≤ .001, whereas it is nonsignificant in the control group. We also observed anthropometric and physiological changes in the participants showing significant effects on weight, BMI, waist circumference, hip circumference, and blood pressure; with no significant effect in the control group. It is one of the first studies done with both two groups, where yoga and meditation are done at high altitude and then seen the changes in the groups at physical and psychological level.

Conclusion: Yogic practices can be helpful in having positive psychological change in the lowlanders at high altitude.

背景:对高海拔的立即认同会影响个体的认知表现和情绪,随之而来的是抑郁和焦虑。它还会影响一个人的睡眠质量、总体健康状况和幸福指数。苏达山克里亚瑜伽(SKY)是一种循环呼吸技巧,已被证明在管理压力、抑郁、焦虑方面很成功,并有助于改善睡眠质量。目的:本研究旨在了解天空冥想对高海拔低地人心理参数、幸福商的影响。方法:采用双臂前后研究方法,实验组和对照组均为低地居民,在立即同意高海拔(Leh)时对其心理参数进行评估。实验组(SKY)来自AOL SKY- amp,有SKY冥想经验。对照组没有任何瑜伽或冥想经验。SKY- amp是SKY小组在高空进行的为期4天的协议。两组人都通过空运到达列城。结果:牛津幸福问卷(OHQ)结果在SKY组有显著性差异(P≤0.001),对照组无显著性差异(P < 0.001)。我们还观察到参与者的人体测量和生理变化,显示出对体重、BMI、腰围、臀围和血压的显著影响;对照组没有明显的效果。这是第一批同时对两组人进行的研究之一,在高海拔地区进行瑜伽和冥想,然后观察两组人在生理和心理层面的变化。结论:瑜伽练习有助于高海拔低地居民产生积极的心理变化。
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引用次数: 0
ADHD and Neuropsychology: Developmental Perspective, Assessment, and Interventions. ADHD与神经心理学:发展观点、评估与干预。
IF 1.5 Q4 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.1177/09727531231171765
Amrina Bhullar, Krishan Kumar, Akshay Anand
Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons AttributionNonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-Commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https:// us.sagepub.com/en-us/nam/open-access-at-sage). Editorial
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引用次数: 0
Use of Anti-epileptic Drugs for Post Traumatic Seizure: A Global Survey. 抗癫痫药物在创伤后癫痫发作中的应用:一项全球调查。
IF 1.5 Q4 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.1177/09727531221120765
Harison Gopalan, Krishnakumar P, Arun S
Background Post traumatic seizures (PTS) and post traumatic epilepsy (PTE) are potential consequences of traumatic brain injury (TBI). There is no consensus regarding its management among treating doctors. Purpose We have undertaken a global survey to assess the variability of management practices of PTS and PTE and highlight the pressing need to formulate uniform practice guidelines. Methods A questionnaire consisting of sixteen questions were developed with the help of Google survey and sent through e-mail, or social media platforms like WhatsApp, Facebook messenger or Telegram, to practicing Neurologists and Neurosurgeons round the world. Results There were a total of 220 responses. Majority of our responders (n = 202; 91.8%) would start an anti-epileptic (AED) prophylaxis to prevent PTS; 18 people (8.18%) told that they would not start AED prophylaxis for TBI. Phenytoin (n = 98; 48.5%) followed by Levetiracetam (n = 78; 38.6%) was the preferred drug, although the latter was significantly preferred by high and upper middle-income countries (p<.001). Majority (n = 99; 49%) would not use it beyond two weeks. Most clinicians would manage PTE with a single drug (n = 160; 72.7%) either Phenytoin (n = 69; 31.3%) or levetiracetam (n = 67; 30.4%). Most of them (n = 174; 86%) would treat for less than one year. Conclusions Practices in the management of PTS and PTE vary widely among clinicians. Our study point towards the need for the development of a more robust and comprehensive practice guidelines for the management of the same.
背景:创伤后癫痫发作(PTS)和创伤后癫痫(PTE)是创伤性脑损伤(TBI)的潜在后果。治疗医生对其管理没有共识。目的:我们进行了一项全球调查,以评估PTS和PTE管理实践的可变性,并强调制定统一实践指南的迫切需要。方法:在谷歌调查的帮助下,开发了一份由16个问题组成的问卷,并通过电子邮件或WhatsApp, Facebook messenger或Telegram等社交媒体平台发送给世界各地的执业神经科医生和神经外科医生。结果:共收到220份问卷。大多数应答者(n = 202;91.8%)会开始抗癫痫(AED)预防PTS;18人(8.18%)表示他们不会因TBI而开始AED预防。苯妥英(n = 98;48.5%),其次是左乙拉西坦(n = 78;38.6%)是首选药物,尽管后者在高收入和中高收入国家明显更受欢迎(p001)。多数(n = 99;49%)不会使用超过两周。大多数临床医生会用单一药物治疗PTE (n = 160;72.7%)或苯妥英(n = 69;31.3%)或左乙拉西坦(n = 67;30.4%)。大多数(n = 174;86%)愿意接受不到一年的治疗。结论:临床医生对PTS和PTE的治疗方法差异很大。我们的研究指向需要制定一套更为健全和全面的管理实践指南。
{"title":"Use of Anti-epileptic Drugs for Post Traumatic Seizure: A Global Survey.","authors":"Harison Gopalan,&nbsp;Krishnakumar P,&nbsp;Arun S","doi":"10.1177/09727531221120765","DOIUrl":"https://doi.org/10.1177/09727531221120765","url":null,"abstract":"Background Post traumatic seizures (PTS) and post traumatic epilepsy (PTE) are potential consequences of traumatic brain injury (TBI). There is no consensus regarding its management among treating doctors. Purpose We have undertaken a global survey to assess the variability of management practices of PTS and PTE and highlight the pressing need to formulate uniform practice guidelines. Methods A questionnaire consisting of sixteen questions were developed with the help of Google survey and sent through e-mail, or social media platforms like WhatsApp, Facebook messenger or Telegram, to practicing Neurologists and Neurosurgeons round the world. Results There were a total of 220 responses. Majority of our responders (n = 202; 91.8%) would start an anti-epileptic (AED) prophylaxis to prevent PTS; 18 people (8.18%) told that they would not start AED prophylaxis for TBI. Phenytoin (n = 98; 48.5%) followed by Levetiracetam (n = 78; 38.6%) was the preferred drug, although the latter was significantly preferred by high and upper middle-income countries (p<.001). Majority (n = 99; 49%) would not use it beyond two weeks. Most clinicians would manage PTE with a single drug (n = 160; 72.7%) either Phenytoin (n = 69; 31.3%) or levetiracetam (n = 67; 30.4%). Most of them (n = 174; 86%) would treat for less than one year. Conclusions Practices in the management of PTS and PTE vary widely among clinicians. Our study point towards the need for the development of a more robust and comprehensive practice guidelines for the management of the same.","PeriodicalId":7921,"journal":{"name":"Annals of Neurosciences","volume":"30 1","pages":"26-32"},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ab/c1/10.1177_09727531221120765.PMC10259155.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9988693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Homocysteine, Vitamins B6, B12, and Folate and the Risk of Ischemic and Hemorrhagic Stroke: A Case-control Study from Northeast India. 同型半胱氨酸、维生素B6、B12和叶酸与缺血性和出血性中风的风险:来自印度东北部的病例对照研究
IF 1.5 Q4 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.1177/09727531221124425
Manash Ghose, Madhumita Das, Rupjyoti Das, Amit Ranjan Barua, Prasenjit Deka, Aparajita Barman, Vivekananda Lahan, Dhruba Jyoti Choudhury, Jai Prakash Sharma, Manik Mathur, Nomal Chandra Borah, Nupur Choudhury, Ananya Barman

Background: Stroke is a major leading global health complication. Identification and management of risk factors associated with stroke can help in prior detection, prevention, and improvement in patient care.

Purpose: To investigate the prevalence of hyperhomocysteinemia (HHcy) and Vitamins B6, B12, and folate deficiency in stroke patients and also to assess other risk factors associated with ischemic and hemorrhagic stroke.

Methods: Detail history of all the subjects in the study including history of hypertension, anemia, fasting glucose, carotid artery thickness, smoking, alcohol, and dietary intake was recorded. Standard assays for homocysteine (Hcy), Vitamins B6, B12, and folate estimation were done. Lipid and renal profile tests were also performed. The prevalence and odds of having HHcy, Vitamins B6, B12, and folate deficiency, and other risk factors in ischemic and hemorrhagic stroke patients were evaluated. Student's t-tests and chi-square tests were done for statistical validation of the data.

Results: Prevalence of HHcy and Vitamins B6, B12, and folate deficiency was not observed in ischemic cases. HHcy and folate deficiency was found to be prevalent in hemorrhagic stroke patients. The odds that a person with HHcy and folate deficiency has hemorrhagic stroke was found to be significantly high.

Conclusion: In our study, high Hcy and low folate levels emerged as risk factors for hemorrhagic stroke.

背景:脑卒中是全球主要的健康并发症。识别和管理与中风相关的危险因素有助于预先发现、预防和改善患者护理。目的:调查脑卒中患者高同型半胱氨酸血症(HHcy)、维生素B6、B12和叶酸缺乏症的患病率,并评估与缺血性和出血性脑卒中相关的其他危险因素。方法:详细记录所有研究对象的病史,包括高血压、贫血、空腹血糖、颈动脉厚度、吸烟、饮酒、饮食摄入等。进行了同型半胱氨酸(Hcy)、维生素B6、B12和叶酸的标准测定。还进行了血脂和肾脏检查。评估缺血性和出血性脑卒中患者HHcy、维生素B6、B12和叶酸缺乏症的患病率和几率,以及其他危险因素。采用学生t检验和卡方检验对数据进行统计验证。结果:在缺血性病例中未观察到HHcy、维生素B6、B12和叶酸缺乏的患病率。出血性中风患者普遍存在HHcy和叶酸缺乏症。患有HHcy和叶酸缺乏症的人患出血性中风的几率非常高。结论:在我们的研究中,高Hcy和低叶酸水平是出血性中风的危险因素。
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引用次数: 1
Therapeutic Potential of Low-Intensity Magnetic Field Stimulation in 6-Hydroxydopamine Rat Model of Parkinson's Disease: From Inflammation to Motor Function. 低强度磁场刺激对6-羟多巴胺大鼠帕金森病模型的治疗潜力:从炎症到运动功能。
IF 1.5 Q4 NEUROSCIENCES Pub Date : 2023-01-01 DOI: 10.1177/09727531221117634
Samrat Bose, Tapas Chandra Nag, Soumil Dey, Monica Sundd, Suman Jain

Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder that mainly affects the aged population. Transcranial magnetic field (MF) stimulation has shown to provide temporary motor recovery in neurological disorders.

Purpose: The aim of this study was to understand the cellular and molecular mechanism of low-intensity MF stimulation (17.96 µT; 50Hz; 2 h/day, four weeks) in a rat model of severe PD.

Methods: A clinically relevant, bilateral striatal 6-hydroxydopamine (6-OHDA) lesioned rat model of severe PD was employed to test the efficacy of low-intensity MF stimulation in the management of motor symptoms. The mechanism of action of MF was dissected by assessing the microglial activation, tissue ultrastructure, and cerebrospinal fluid (CSF) metabolomics using microdialysis.

Results: We observed a significant improvement in the postural balance and gait after MF exposure with a significant reduction in the number of activated microglia. There was an improvement in striatal dopaminergic innervation and glutamate levels but it did not reach a level of statistical significance.

Conclusion: MF stimulation helped ameliorate the motor deficits and reduced inflammation but was unable to provide a significant change in terms of dopaminergic innervation and metabolic profile in the severe 6-OHDA PD rat model.

背景:帕金森病(PD)是一种主要影响老年人的进行性神经退行性疾病。经颅磁场(MF)刺激已显示提供暂时的运动恢复神经系统疾病。目的:探讨低强度中频刺激(17.96µT;50赫兹;2小时/天,4周)。方法:采用临床相关的双侧纹状体6-羟多巴胺(6-OHDA)损伤大鼠模型,检测低强度MF刺激对运动症状的治疗效果。通过微透析观察小胶质细胞活化、组织超微结构和脑脊液代谢组学,探讨MF的作用机制。结果:我们观察到MF暴露后姿势平衡和步态的显着改善,激活的小胶质细胞数量显着减少。纹状体多巴胺能神经支配和谷氨酸水平均有改善,但未达到统计学意义。结论:在6-OHDA重度PD大鼠模型中,MF刺激有助于改善运动缺陷和减轻炎症,但不能显著改变多巴胺能神经支配和代谢谱。
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引用次数: 0
Clinical Contribution Towards Management of COVID-19 Patients with Yoga and Naturopathy Intervention. 通过瑜伽和自然疗法干预管理 COVID-19 患者的临床贡献。
IF 1.8 Q4 NEUROSCIENCES Pub Date : 2022-10-01 Epub Date: 2022-10-19 DOI: 10.1177/09727531221130558
Poornima Ravi, Venugopal Vijayakumar, Maheshkumar Kuppusamy, Velan Arumugam
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引用次数: 0
Online Yoga and Ayurveda Intervention as Tertiary Prevention of Psychological Comorbidities in COVID-19 Survivors: A Randomized Controlled Trial. 在线瑜伽和阿育吠陀干预作为COVID-19幸存者心理合并症的三级预防:一项随机对照试验
IF 1.5 Q4 NEUROSCIENCES Pub Date : 2022-10-01 DOI: 10.1177/09727531221117623
Rudra Bhandari

Background and purpose: About 56% of symptomatic COVID-19 survivors have been found with neuropsychological comorbidities, such as depression, anxiety, posttraumatic stress disorders (PTSD), and impaired quality of life (QoL). Alongside, antimicrobial, anti-inflammatory, neuroprotective, regenerative, immunomodulatory, cardio-pulmonary health promotive, and psychological benefits of yogic and Ayurvedic intervention are well documented. Therefore, this study aimed to assess the effect of online Yoga (OYI) and Yoga cum Ayurveda intervention (OYAI) on COVID-19-induced depression, anxiety, PTSD, and poor QoL.

Method: Seventy-two participants (males/females: 33/26) with at least a 3-month back history of symptomatic COVID-19 infection and age (mean ± SD: 32.33 ± 9.9 and 33.04 ± 12.9 for males and females, respectively) were recruited from Patanjali Ayurveda Hospital, Haridwar, India, and All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India, before random allocation into an equal-sized control group (CG), Yoga group (YG) and Yoga cum concoction (YCG) group. Split-plot analysis of variance and Kruskal-Wallis tests with Bonferroni adjusted post hoc comparisons were computed for normal and nonnormal data using IBM SPSS (25th Version, SPSS South Asia Private Limited, Bangalore, India).

Results: Both the treatments-the 30-day OYI and OYAI, significantly improved depression (P < .002, ES: -0.99 and P < .001, ES: -2.11), anxiety (P < .001, ES: -1.32 and -1.89), PTSD (P < .001, ES: -1.8 and -1.83) and QoL related constructs (P < .001, ES: 0.63 and 0.76; 0.71 and 0.93 for each OYI and OYAI versus general health and physical health; P < .001, ES: 0.65 for OYAI versus psychological health; and P < .003, ES: 0.54 for OYI versus environment) of the participants compared to the controls.

Conclusion: OYAI may better ameliorate COVID-19-induced psychological comorbidities than OYI with no adverse effects.

背景和目的:约56%的有症状的COVID-19幸存者被发现患有神经心理合并症,如抑郁、焦虑、创伤后应激障碍(PTSD)和生活质量受损(QoL)。此外,抗微生物、抗炎、神经保护、再生、免疫调节、促进心肺健康以及瑜伽和阿育吠陀干预的心理益处也得到了很好的证明。因此,本研究旨在评估在线瑜伽(OYI)和瑜伽与阿育吠陀干预(OYAI)对covid -19诱导的抑郁、焦虑、创伤后应激障碍和不良生活质量的影响。方法:从印度哈里德瓦尔的帕坦伽利阿育吠陀医院和印度北阿坎德邦里希凯什的全印度医学科学研究所招募了72名至少有3个月症状性COVID-19感染史和年龄的参与者(男/女:33/26)(平均±SD分别为32.33±9.9和33.04±12.9),然后随机分为等量对照组(CG)、瑜伽组(YG)和瑜伽混合剂组(YCG)。使用IBM SPSS(第25版,SPSS南亚私人有限公司,班加罗尔,印度)计算正态和非正态数据的分裂图方差分析和经Bonferroni调整后的Kruskal-Wallis检验。结果:30天OYI和oai治疗均显著改善抑郁(P < 002, ES: -0.99和P < 0.001, ES: -2.11)、焦虑(P < 0.001, ES: -1.32和-1.89)、创伤后应激障碍(P < 0.001, ES: -1.8和-1.83)和生活质量相关结构(P < 0.001, ES: 0.63和0.76;总体健康和身体健康的OYI和oai分别为0.71和0.93;与心理健康的比较,P < 0.001, ES: 0.65;P < 0.003, ES: 0.54 (OYI vs .环境)。结论:与OYI相比,oai可更好地改善covid -19诱导的心理合并症,且无不良反应。
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引用次数: 1
期刊
Annals of Neurosciences
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