Annals of Nuclear Medicine最新文献

{"title":"Perfusion-only SPECT/CT for pulmonary thromboembolism: from promising criteria to globally reproducible practice","authors":"M. Vijayasimha, M. Srikanth","doi":"10.1007/s12149-026-02160-w","DOIUrl":"10.1007/s12149-026-02160-w","url":null,"abstract":"","PeriodicalId":8007,"journal":{"name":"Annals of Nuclear Medicine","volume":"40 2","pages":"226 - 227"},"PeriodicalIF":2.5,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146117670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Registration accuracy of amyloid/tau-PET to brain MRI using modified SPM method.","authors":"Yuma Iwao, Go Akamatsu, Muneyuki Sakata, Kei Wagatsuma, Kenji Ishii, Taiga Yamaya, Miwako Takahashi","doi":"10.1007/s12149-026-02159-3","DOIUrl":"https://doi.org/10.1007/s12149-026-02159-3","url":null,"abstract":"","PeriodicalId":8007,"journal":{"name":"Annals of Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146117742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complementary prognostic value of hotspot-to-centroid distance (NHOCpeak) to SUVpeak in high-grade glioma.","authors":"Jesús J Bosque, David Molina-García, Julián Pérez-Beteta, Ana M García Vicente, Víctor M Pérez-García","doi":"10.1007/s12149-025-02138-0","DOIUrl":"https://doi.org/10.1007/s12149-025-02138-0","url":null,"abstract":"","PeriodicalId":8007,"journal":{"name":"Annals of Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146103574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Off-target binding of ¹⁸F-MK-6240 tau PET imaging demonstrated by high spatial resolution dedicated brain PET scanner.","authors":"Kazunari Ishii, Takahiro Yamada, Kohei Hanaoka, Hayato Kaida, Yasuyuki Kojita, Atsushi Kono, Kenji Ishii, Takashi Kato, Akinori Nakamura","doi":"10.1007/s12149-026-02161-9","DOIUrl":"https://doi.org/10.1007/s12149-026-02161-9","url":null,"abstract":"","PeriodicalId":8007,"journal":{"name":"Annals of Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146103694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of metabolic parameters from PET/CT in adult multifocal Langerhans cell histiocytosis.","authors":"Hui-Min Shan, Tao Chen, Wei Fan","doi":"10.1007/s12149-026-02154-8","DOIUrl":"https://doi.org/10.1007/s12149-026-02154-8","url":null,"abstract":"","PeriodicalId":8007,"journal":{"name":"Annals of Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of magnetic resonance image-based motion correction on the centiloid scale: a comparison with and without correction.","authors":"Ryo Yamakuni, Naoyuki Ukon, Takashi Kanezawa, Hironobu Ishikawa, Takeyasu Kakamu, Takenobu Murakami, Keijiro Saito, Motoharu Hakozaki, Hirofumi Sekino, Shiro Ishii, Kenji Fukushima, Hitoshi Kubo, Hiroshi Ito","doi":"10.1007/s12149-026-02156-6","DOIUrl":"https://doi.org/10.1007/s12149-026-02156-6","url":null,"abstract":"","PeriodicalId":8007,"journal":{"name":"Annals of Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Somatostatin receptor expression for peptide receptor radionuclide therapy in Japanese patients with recurrent or metastatic differentiated thyroid cancer.","authors":"Shiro Watanabe, Kenji Hirata, Junki Takenaka, Yamato Munakata, Keiichi Magota, Naoto Wakabayashi, Hiroto Koga, Kohsuke Kudo","doi":"10.1007/s12149-026-02155-7","DOIUrl":"https://doi.org/10.1007/s12149-026-02155-7","url":null,"abstract":"","PeriodicalId":8007,"journal":{"name":"Annals of Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional distribution of an amyloid radiotracer in healthy aged human brain measured by PET with [¹⁸F]flutemetamol: a relation with myelin distribution.","authors":"Hiroshi Ito, Ryo Yamakuni, Harumasa Takano, Mitsunari Abe, Atsushi Shima, Nobukatsu Sawamoto, Takashi Hanakawa","doi":"10.1007/s12149-026-02158-4","DOIUrl":"https://doi.org/10.1007/s12149-026-02158-4","url":null,"abstract":"","PeriodicalId":8007,"journal":{"name":"Annals of Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochemical failure after radical prostatectomy with PSA ≤ 1 ng/mL: prediction of PSMA-positive metastatic disease.","authors":"Giulia Santo, Helena Rosarno, Antonino Restuccia, Giuseppe Lucio Cascini, Francesco Grillone, Francesco Cicone","doi":"10.1007/s12149-026-02153-9","DOIUrl":"https://doi.org/10.1007/s12149-026-02153-9","url":null,"abstract":"<p><strong>Objectives: </strong>The identification of metastatic disease in patients with biochemical failure of prostate cancer (PCa) after radical prostatectomy (RP) determines subsequent treatment management. Our objectives were (i) to assess the prevalence of metastatic PCa in patients with biochemical failure following RP and PSA levels ≤ 1 ng/mL, as detected by ¹⁸F-PSMA-1007 PET/CT (PSMA-PET), and (ii) to identify predictors of metastatic disease.</p><p><strong>Methods: </strong>Fifty-five patients with biochemical recurrence (BCR, n = 47) or persistent disease (n = 8) following RP as their primary and only prior treatment were retrospectively included if presenting with PSA levels ≤ 1 ng/mL. Patients who received any other anticancer treatment were excluded. PSMA-PET findings were categorized as either local recurrence (i.e., prostatic fossa and seminal vesicles) or metastases. Predictors of PSMA-PET positivity were assessed with univariate and multivariate regression analyses both in the whole sample and in two subgroups defined according to PSA levels (Group A = PSA < 0.5 ng/mL; Group B = PSA between 0.5 and 1 ng/mL).</p><p><strong>Results: </strong>Median PSA at the time of PET/CT was 0.37 ng/mL (range: 0.13-1.0). PSMA-PET was positive in 22/55 (40%) patients, 14/55 (25%) patients had metastatic disease. Overall, 31 PSMA-positive lesions were identified: 12/31 (39%) and 19/31 (61%) were local recurrences and metastases, respectively. In the whole cohort, ISUP grade > 3 (p = 0.003), pN1 status after surgery (p = 0.011), time to BCR ≤ 26 months (p = 0.03), and persistent disease (p = 0.003) were significantly associated with a higher rate of PSMA-positive metastases. At multivariate analysis, ISUP grade > 3 (p = 0.016) was the only independent predictor of metastases. Metastatic disease was detected in 8/38 (21%) patients in Group A and in 6/17 (35%) patients in Group B, respectively. In Group A, pN1 (p = 0.043) and persistent disease (p = 0.040) were significant predictors of metastases. In Group B, ISUP grade > 3 was the only predictor (p = 0.028).</p><p><strong>Conclusions: </strong>ISUP grade > 3, time to BCR ≤ 26 months, pN1 status, and persistent disease after surgery indicated a higher likelihood of PSMA-positive metastatic disease in a homogeneous cohort of patients with biochemical failure and low PSA values. pN1 status and persistent disease were significant predictors of metastatic disease also in patients with PSA levels < 0.5 ng/mL.</p>","PeriodicalId":8007,"journal":{"name":"Annals of Nuclear Medicine","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145984307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical applications and future directions of Iodine-131-Metaiodobenzylguanidine therapy in neuroblastoma: from salvage treatment to frontline integration","authors":"Hoang Minh Chau Vu,&nbsp;Daiki Kayano,&nbsp;Hiroshi Wakabayashi,&nbsp;Rie Kuroda,&nbsp;Seigo Kinuya","doi":"10.1007/s12149-025-02151-3","DOIUrl":"10.1007/s12149-025-02151-3","url":null,"abstract":"<div>\u0000 \u0000 <p>Neuroblastoma is the most common extracranial solid tumor in children and often requires complex, multimodal treatment. A major advancement in its treatment has been the development of metaiodobenzylguanidine (MIBG), a norepinephrine analog, for diagnostic imaging and targeted radiotherapy. This review provides a comprehensive overview of the clinical applications and recent advancements of ¹³¹I-MIBG in neuroblastoma treatment. The agent has exhibited substantial efficacy in newly diagnosed and relapsed or refractory disease, through strategies such as monotherapy, tandem dosing, and high-dose administration with stem cell transplantation support. Combination regimens incorporating radiosensitizers, chemotherapeutic agents, and novel targeted approaches-including histone deacetylase inhibitors and immunotherapy-have further broadened its therapeutic scope. Challenges remain, including nonavid tumors, radiation-related risks, and logistical constraints. However, with the recent regulatory approval of ¹³¹I-MIBG for neuroblastoma treatment in Japan, its role is expected to expand, paving the way for improved outcomes and more personalized, targeted approaches in pediatric oncology.</p>\u0000 </div>","PeriodicalId":8007,"journal":{"name":"Annals of Nuclear Medicine","volume":"40 3","pages":"248 - 263"},"PeriodicalIF":2.5,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12935704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145958282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}