Pub Date : 2021-01-01DOI: 10.36648/2386-5180.21.9.335
Fadhlullah Latama, Habibah S. Muhiddin Budu, A. M. Ichsan, M. Akib, A. T. Poli
TIntroduction: Waardenberg syndrome is a rare condition characterised by heterochromia or bright blue irides, hypertelorism due to wider nasal bridge, sensory neural deafness and hypopigmentation of the skin and hair (poliosis). It is usually inherited in autosomal dominant pattern, however it can also be recessive Objective: To report clinical manifestations of type 1 Waardenberg Syndrome in a family of four generations. Case Presentation: Ten members of a family presented manifestations of Waardenberg Syndrome. Three of them had bright blue irides in both eyes, 4 had heterochromia. Two of the members with bright blue irides also had sensorineural hearing loss, poliosis accompanied by broad nasal bridge. Three others only showed hypertelorism and poliosis. All members of the family had normal visual acuity. There is no history of consanguineous marriage reported. Conclusion: The family in this case presumably inherited autosomal dominant of type 1 Waardenberg syndrome.
{"title":"A Family with Autosomal Dominant Inheritance of Type 1 Waardenberg Syndrome","authors":"Fadhlullah Latama, Habibah S. Muhiddin Budu, A. M. Ichsan, M. Akib, A. T. Poli","doi":"10.36648/2386-5180.21.9.335","DOIUrl":"https://doi.org/10.36648/2386-5180.21.9.335","url":null,"abstract":"TIntroduction: Waardenberg syndrome is a rare condition characterised by heterochromia or bright blue irides, hypertelorism due to wider nasal bridge, sensory neural deafness and hypopigmentation of the skin and hair (poliosis). It is usually inherited in autosomal dominant pattern, however it can also be recessive Objective: To report clinical manifestations of type 1 Waardenberg Syndrome in a family of four generations. Case Presentation: Ten members of a family presented manifestations of Waardenberg Syndrome. Three of them had bright blue irides in both eyes, 4 had heterochromia. Two of the members with bright blue irides also had sensorineural hearing loss, poliosis accompanied by broad nasal bridge. Three others only showed hypertelorism and poliosis. All members of the family had normal visual acuity. There is no history of consanguineous marriage reported. Conclusion: The family in this case presumably inherited autosomal dominant of type 1 Waardenberg syndrome.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"128 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74895722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/2386-5180.21.9.333
Anusha Polampelli
Our main is to bring together all the articles and their scope under one roof, the annals of clinical and laboratory research is a peer review journal that bring all the advancements in the clinical research. Our main motto is to keep the information or knowledge up to date so that it will be easily conveyed to the readers of our journal.
{"title":"A Short Note on the Recently Published Articles In Annals 0f Clinical and Laboratory Research","authors":"Anusha Polampelli","doi":"10.36648/2386-5180.21.9.333","DOIUrl":"https://doi.org/10.36648/2386-5180.21.9.333","url":null,"abstract":"Our main is to bring together all the articles and their scope under one roof, the annals of clinical and laboratory research is a peer review journal that bring all the advancements in the clinical research. Our main motto is to keep the information or knowledge up to date so that it will be easily conveyed to the readers of our journal.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"21 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85653608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/2386-5180.21.9.343
E. Koifman
In recent years, transcatheter aortic valve implantation (TAVI) has been shown to be a valid option of treatment for patients with severe aortic stenosis requiring valve therapy. Initially shown to be equivalent to surgical aortic valve replacement (SAVR) in prohibitive and high surgical risk patients, TAVI gradually expanded to intermediate and lower risk patients, the devices have evolved and improved with lower delivery profile and improved sealing to prevent paravalvular leak along with various techniques such as transcaval, transaxilary and transcarotid, enabling percutaneous treatment in challenging anatomies. In addition, additional devices were developed to improve patient safety by stroke prevention during the procedure and bleeding prevention during access closure. These advances in TAVI procedure were translated to improved patient outcome with superiority of TAVI over SAVR in low-risk patients and expansion of TAVI indication to challenging anatomies and lower risk patients.
{"title":"Overview of Advances in Transcatheter Aortic Valve Implantation","authors":"E. Koifman","doi":"10.36648/2386-5180.21.9.343","DOIUrl":"https://doi.org/10.36648/2386-5180.21.9.343","url":null,"abstract":"In recent years, transcatheter aortic valve implantation (TAVI) has been shown to be a valid option of treatment for patients with severe aortic stenosis requiring valve therapy. Initially shown to be equivalent to surgical aortic valve replacement (SAVR) in prohibitive and high surgical risk patients, TAVI gradually expanded to intermediate and lower risk patients, the devices have evolved and improved with lower delivery profile and improved sealing to prevent paravalvular leak along with various techniques such as transcaval, transaxilary and transcarotid, enabling percutaneous treatment in challenging anatomies. In addition, additional devices were developed to improve patient safety by stroke prevention during the procedure and bleeding prevention during access closure. These advances in TAVI procedure were translated to improved patient outcome with superiority of TAVI over SAVR in low-risk patients and expansion of TAVI indication to challenging anatomies and lower risk patients.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87599245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/2386-5180.21.9.368
S. Javaria
Participation in a standard exercise program is a compelling intercession to diminish and forestall various practical and wellbeing related weaknesses known to happen with propelling age. Useful advantages of standard exercise remember increments for cardiovascular wellness, muscle strength, and practical limit, permitting more established people to keep up with their autonomy and unreservedly take an interest in day by day exercises. What's more, routine exercise, intense exercise, or both can forestall or extraordinarily weaken the age-related expansions in hazard factors for coronary illness. Taken together, these advantages related with ordinary exercise can fundamentally work on the personal satisfaction in more established populaces.
{"title":"Effective Interventions to Reduce and Prevent Functional and Health-Associated Impairments in Elderly","authors":"S. Javaria","doi":"10.36648/2386-5180.21.9.368","DOIUrl":"https://doi.org/10.36648/2386-5180.21.9.368","url":null,"abstract":"Participation in a standard exercise program is a compelling intercession to diminish and forestall various practical and wellbeing related weaknesses known to happen with propelling age. Useful advantages of standard exercise remember increments for cardiovascular wellness, muscle strength, and practical limit, permitting more established people to keep up with their autonomy and unreservedly take an interest in day by day exercises. What's more, routine exercise, intense exercise, or both can forestall or extraordinarily weaken the age-related expansions in hazard factors for coronary illness. Taken together, these advantages related with ordinary exercise can fundamentally work on the personal satisfaction in more established populaces.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89676568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and Aim: Hemorrhoidal Disease (HD) is a chronic pathology and is fairly common in the general population. For this reason, conservative therapies need to be at the same time effective and tolerated. The topical medications available usually contain either a combination of local anesthetics with antiâ?ÂÂinflammatories or muscle relaxants, thus addressing a single mechanism, if any, of those that underlie symptoms onset. As a consequence, evidence of efficacy of these drugs is currently limited and the needed tolerability and safety from a topical treatment of HD is not always evident. The aim of the present study was to evaluate efficacy and tolerability of a 100% natural ointment, a medical device made of substances, for the symptomatic treatment of HD. Methods: Symptomatic grade I or II HD patients with 0-100 VAS score for HD-related discomfort ≥ 30 were treated for 10 days. Outcome measures included variation of HD subjective symptoms (discomfort, pain, itching and burning) and objective signs (bleeding and anal leakage) at day 3, 7 and 10, and the presence of prolapse after treatment. Statistical analysis: For the analysis of primary endpoint (i.e. reduction of discomfort), missing data in the full analysis set (FAS) population were replaced using the “Last Observation Carried Forward” (LOCF) method. For the analyses of the secondary end point, Poisson mixed model was used to evaluate symptom variation (VAS). Bleeding and anal leakage were recoded as negative or positive in two different variables (grade 1 and 2) derived from their frequency (i.e., for grade1, each of the clinical signs was considered Negative if the patient reported frequency was “Never”; recoded as Positive if any other frequency category was reported) and frequencies of positive patients in each grade were compared by Logistic Mixed model. Mixed models were used to take in account repeated data for the same subject. Missing values in quantitative data analysing by Mixed model were imputed by statistical interpolation. In analysing bleeding, anal leakage and presence of prolapse in FAS population, missing data where either replaced using the LOCF method or imputed as positive (i.e., worst case). Results: 45 patients were enrolled. Data showed a significant reduction of discomfort in treated patients both during and after treatment (p<0.001 at all-time points evaluated), with a median VAS score decrease of 30 points after treatment when compared to baseline. The same significant reduction (p<0.001) was shown for all other symptoms either at the end of treatment or at earlier time points, both in PP and FAS populations. As for objective signs, a significant reduction was observed, at each time point compared to baseline, in the number of patients from the PP population positive for bleeding (p<0.001) and anal leakage (p<0.05). A similar evolution was shown in FAS population, where reduction was progressive over the 10-day treatment and statistically significant or
{"title":"Prospective Interventional Study to Evaluate the Effect of a Medical Device Made of Substances in Reducing Signs and Symptoms in Patients with Hemorrhoidal Disease","authors":"Podda Mariangela, Laureti, Sílvio, Gentilini Lorenzo, Vittori Laura, Poggioli, Gilberto","doi":"10.36648/2386-5180.21.9.345","DOIUrl":"https://doi.org/10.36648/2386-5180.21.9.345","url":null,"abstract":"Background and Aim: Hemorrhoidal Disease (HD) is a chronic pathology and is fairly common in the general population. For this reason, conservative therapies need to be at the same time effective and tolerated. The topical medications available usually contain either a combination of local anesthetics with antiâ?ÂÂinflammatories or muscle relaxants, thus addressing a single mechanism, if any, of those that underlie symptoms onset. As a consequence, evidence of efficacy of these drugs is currently limited and the needed tolerability and safety from a topical treatment of HD is not always evident. The aim of the present study was to evaluate efficacy and tolerability of a 100% natural ointment, a medical device made of substances, for the symptomatic treatment of HD. Methods: Symptomatic grade I or II HD patients with 0-100 VAS score for HD-related discomfort ≥ 30 were treated for 10 days. Outcome measures included variation of HD subjective symptoms (discomfort, pain, itching and burning) and objective signs (bleeding and anal leakage) at day 3, 7 and 10, and the presence of prolapse after treatment. Statistical analysis: For the analysis of primary endpoint (i.e. reduction of discomfort), missing data in the full analysis set (FAS) population were replaced using the “Last Observation Carried Forward” (LOCF) method. For the analyses of the secondary end point, Poisson mixed model was used to evaluate symptom variation (VAS). Bleeding and anal leakage were recoded as negative or positive in two different variables (grade 1 and 2) derived from their frequency (i.e., for grade1, each of the clinical signs was considered Negative if the patient reported frequency was “Never”; recoded as Positive if any other frequency category was reported) and frequencies of positive patients in each grade were compared by Logistic Mixed model. Mixed models were used to take in account repeated data for the same subject. Missing values in quantitative data analysing by Mixed model were imputed by statistical interpolation. In analysing bleeding, anal leakage and presence of prolapse in FAS population, missing data where either replaced using the LOCF method or imputed as positive (i.e., worst case). Results: 45 patients were enrolled. Data showed a significant reduction of discomfort in treated patients both during and after treatment (p<0.001 at all-time points evaluated), with a median VAS score decrease of 30 points after treatment when compared to baseline. The same significant reduction (p<0.001) was shown for all other symptoms either at the end of treatment or at earlier time points, both in PP and FAS populations. As for objective signs, a significant reduction was observed, at each time point compared to baseline, in the number of patients from the PP population positive for bleeding (p<0.001) and anal leakage (p<0.05). A similar evolution was shown in FAS population, where reduction was progressive over the 10-day treatment and statistically significant or","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86967589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/2386-5180.21.9.367
Mamatha Dereddy
Primary cutaneous aspergillosis (PCA) is one of several invasive fungal infections that have increased in incidence in the last four decades. We present an instance of an amazingly low birth weight newborn child brought into the world at 24 weeks growth determined to have cutaneous aspergillosis, featuring the danger factors and clinical discoveries related with neonatal PCA. Furthermore, we talk about utilization of serum galactomannan testing just as mix amphotericin B and voriconazole treatment. Early acknowledgment of injuries normal for PCA is needed to guarantee brief finding and treatment, conceivably forestalling scattering with ideal results [1].
{"title":"Primary Cutaneous aspergillosis: Rash in an Infant Born with Less Weight","authors":"Mamatha Dereddy","doi":"10.36648/2386-5180.21.9.367","DOIUrl":"https://doi.org/10.36648/2386-5180.21.9.367","url":null,"abstract":"Primary cutaneous aspergillosis (PCA) is one of several invasive fungal infections that have increased in incidence in the last four decades. We present an instance of an amazingly low birth weight newborn child brought into the world at 24 weeks growth determined to have cutaneous aspergillosis, featuring the danger factors and clinical discoveries related with neonatal PCA. Furthermore, we talk about utilization of serum galactomannan testing just as mix amphotericin B and voriconazole treatment. Early acknowledgment of injuries normal for PCA is needed to guarantee brief finding and treatment, conceivably forestalling scattering with ideal results [1].","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"158 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83237055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/2386-5180.21.9.354
E. Chacon-Cruz, E. Lopatynsky-Reyes, David López-Martínez, Angel De La Torre-Gomez
Introduction: In Mexico, universal Varicella vaccination is not part of the National Immunization Program. Community-Acquired Methicillin-Resistant Staphylococcus Aureus (CA-MRSA) infection is increasing worldwide. CA-MRSA infection in children with Varicella has scarcely been reported. Methods and Findings: From January-2012 to December-2018, we performed active surveillance for children <16 years of age hospitalized with Varicella at the Tijuana General Hospital, Mexico. To all patients with suspected bacterial super infection, a culture sampling was conducted. CA-MRSA was described and identified by both in vitro resistance to methicillin and other isoxazolyl penicillins and by identifying the gene mec-A by PCR. A total of 40 patients were enrolled. The median age at admission was 20.5 months (1-190). All but 4 (10%) were previously healthy children. None were vaccinated against Varicella. Cellulitis (with/without abscess) was the leading complication (50%), with 70% CA-MRSA identified in abscesses. Septicemia/bacteremia was present in 10 (25%), blood isolation was confirmed in seven (3 S. aureus (all CA-MRSA), 2 S. pyogenes, 1 S. pneumoniae, 1 E. coli). Conclusion: Hospitalizations by Varicella in our Hospital are not infrequent; they are associated with high morbidity and relatively low mortality. The leading complication was bacterial super infection represented by soft-tissue infections and bacteremia/septicemia mostly due to CA-MRSA. Keywords: Varicella; Methicillin-Resistant Staphylococcus Aureus (MRSA); Community Acquired Methicillin-Resistant Staphylococcus Aureus (CA-MRSA); Varicella vaccine; Antibiotic control
{"title":"Varicella Hospitalizations and Community-Acquired Methicillin-Resistant Staphylococcus aureus: Seven Years of Active Surveillance","authors":"E. Chacon-Cruz, E. Lopatynsky-Reyes, David López-Martínez, Angel De La Torre-Gomez","doi":"10.36648/2386-5180.21.9.354","DOIUrl":"https://doi.org/10.36648/2386-5180.21.9.354","url":null,"abstract":"Introduction: In Mexico, universal Varicella vaccination is not part of the National Immunization Program. Community-Acquired Methicillin-Resistant Staphylococcus Aureus (CA-MRSA) infection is increasing worldwide. CA-MRSA infection in children with Varicella has scarcely been reported. Methods and Findings: From January-2012 to December-2018, we performed active surveillance for children <16 years of age hospitalized with Varicella at the Tijuana General Hospital, Mexico. To all patients with suspected bacterial super infection, a culture sampling was conducted. CA-MRSA was described and identified by both in vitro resistance to methicillin and other isoxazolyl penicillins and by identifying the gene mec-A by PCR. A total of 40 patients were enrolled. The median age at admission was 20.5 months (1-190). All but 4 (10%) were previously healthy children. None were vaccinated against Varicella. Cellulitis (with/without abscess) was the leading complication (50%), with 70% CA-MRSA identified in abscesses. Septicemia/bacteremia was present in 10 (25%), blood isolation was confirmed in seven (3 S. aureus (all CA-MRSA), 2 S. pyogenes, 1 S. pneumoniae, 1 E. coli). Conclusion: Hospitalizations by Varicella in our Hospital are not infrequent; they are associated with high morbidity and relatively low mortality. The leading complication was bacterial super infection represented by soft-tissue infections and bacteremia/septicemia mostly due to CA-MRSA. Keywords: Varicella; Methicillin-Resistant Staphylococcus Aureus (MRSA); Community Acquired Methicillin-Resistant Staphylococcus Aureus (CA-MRSA); Varicella vaccine; Antibiotic control","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79184877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/2386-5180.21.9.339
Áron
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) of presumed autoimmune origin which develops in a genetic susceptible individual triggered by additional environmental factors. In this review we'll provide an update of basic pathogenic concepts. In addition, we'll discuss newly evolving concepts in MS pathogenesis like pathogenic heterogeneity, importance of axonal loss and therefore the role of CD8+ T lymphocytes in tissue injury.
{"title":"Research and Recent Advancements on Multiple Sclerosis","authors":"Áron","doi":"10.36648/2386-5180.21.9.339","DOIUrl":"https://doi.org/10.36648/2386-5180.21.9.339","url":null,"abstract":"Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) of presumed autoimmune origin which develops in a genetic susceptible individual triggered by additional environmental factors. In this review we'll provide an update of basic pathogenic concepts. In addition, we'll discuss newly evolving concepts in MS pathogenesis like pathogenic heterogeneity, importance of axonal loss and therefore the role of CD8+ T lymphocytes in tissue injury.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72933684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/2386-5180.21.9.356
Anusha Polampelli
Anesthesiology the medical specialty involved with the full perioperative care of patients before, throughout, and once surgery, it encompasses physiologicalstate, medical care drugs, vital medicine, and pain drugs. A Doctorspecialized during this field of medication is termed AN anesthesiologist. The core part of the specialty is that the study and use of physiological state and anesthetics to soundly support a patient's important functions through the perioperative amount. Since the nineteenth century, Anesthesiology has developed from an experimental space with non-specialist practitioner’s exploitation novel, untested medication, and techniques into what is currently an extremely refined, safe, and effective field of medication. In some countries anesthesiologists comprise the biggest single cohort of doctors in hospitals, and their role will extend so much on the far side the standard role of physiological state care within as well as fields like providing pre-hospital medicine, running medical care units, transporting critically unwell patients between facilities, and rehabilitation programs to optimize patients for surgery.
{"title":"Short Communication on Anesthesiology","authors":"Anusha Polampelli","doi":"10.36648/2386-5180.21.9.356","DOIUrl":"https://doi.org/10.36648/2386-5180.21.9.356","url":null,"abstract":"Anesthesiology the medical specialty involved with the full perioperative care of patients before, throughout, and once surgery, it encompasses physiologicalstate, medical care drugs, vital medicine, and pain drugs. A Doctorspecialized during this field of medication is termed AN anesthesiologist. The core part of the specialty is that the study and use of physiological state and anesthetics to soundly support a patient's important functions through the perioperative amount. Since the nineteenth century, Anesthesiology has developed from an experimental space with non-specialist practitioner’s exploitation novel, untested medication, and techniques into what is currently an extremely refined, safe, and effective field of medication. In some countries anesthesiologists comprise the biggest single cohort of doctors in hospitals, and their role will extend so much on the far side the standard role of physiological state care within as well as fields like providing pre-hospital medicine, running medical care units, transporting critically unwell patients between facilities, and rehabilitation programs to optimize patients for surgery.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"111 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74114011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/2386-5180.21.9.363
Gowthami Bainaboina
Multiple sclerosis is a chronic disease which effects the central nervous system, especially the brain, spinal cord, and optic nerves. This can lead to many symptoms in the body Scientists do not know exactly what causes MS, but they believe it is an autoimmune disorder that affects the central nervous system (CNS). When a person has an autoimmune disease, the immune system attacks healthy tissue in the body, just as it might attack a virus or bacteria, In the case of MS, the immune system attacks the myelin sheath that surrounds and protects the nerve fibers, which causes inflammation. Myelin also helps the nerves conduct electrical signals quickly and efficiently.
{"title":"A Short Note on Multiple Sclerosis and its Types","authors":"Gowthami Bainaboina","doi":"10.36648/2386-5180.21.9.363","DOIUrl":"https://doi.org/10.36648/2386-5180.21.9.363","url":null,"abstract":"Multiple sclerosis is a chronic disease which effects the central nervous system, especially the brain, spinal cord, and optic nerves. This can lead to many symptoms in the body Scientists do not know exactly what causes MS, but they believe it is an autoimmune disorder that affects the central nervous system (CNS). When a person has an autoimmune disease, the immune system attacks healthy tissue in the body, just as it might attack a virus or bacteria, In the case of MS, the immune system attacks the myelin sheath that surrounds and protects the nerve fibers, which causes inflammation. Myelin also helps the nerves conduct electrical signals quickly and efficiently.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"23 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91514034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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