首页 > 最新文献

Annals of Clinical and Laboratory Research最新文献

英文 中文
Comparison of Calcium, Phosphorous and 25 (OH)D2 Levels in Sedentary and Labourer Females 久坐和劳动女性钙、磷和25 (OH)D2水平的比较
Pub Date : 2019-01-01 DOI: 10.21767/2386-5180.100289
M. Bashir, B. K. Gupta, Omar Naushad, Nilesh Ch, ra, Abhishek Gupta
Aim: To compare serum calcium, serum phosphorous and serum 25 (OH)D2 levels in sedentary less exposed to sun and heavy working females exposed to sun. Materials and methods: The study was performed in the Biochemistry Department, Subharti Medical College, Swami Vivekananda Subharti University, Meerut. 50 females, 21-50 years of age as labourers (control); 50 other healthy females of same age group sedentary ( cases) were included. All the samples were processed in related automatic machines Vidas and Vitros 350/Fusion by Biomerieux. Results: In our study we found that the levels of serum calcium were 7.25 ± 1.14, serum phosphorous 3.99 ± 0.69 and vitamin D 8.39 ± 2.86 in cases and levels of serum calcium were 8.72 ± 0.58, phosphorous 4.44 ± 0.59 and vitamin D 32.51 ± 6.92 in the control group respectively. Conclusion: Our study perceived that the level of serum Calcium, Phosphorus and vitamin D were significantly decreased in females, less exposed to sun as compared to heavy working females exposed to sun. Thus we could conclude that the maintenance of normal levels of vitamin D is contributed not only by adequate exposure to sun light and exercise, but also to the dietary habits.
目的:比较久坐少晒和重度晒女性血清钙、磷和血清25 (OH)D2水平。材料和方法:研究在密鲁特Swami Vivekananda Subharti大学Subharti医学院生物化学系进行。50名女性,21-50岁的劳动者(对照);另外50例同年龄组的健康女性久坐不动(病例)。所有样品均在生物梅里埃公司的Vidas和Vitros 350/Fusion全自动机器上进行处理。结果:患者血清钙含量为7.25±1.14,血清磷含量为3.99±0.69,血清维生素D含量为8.39±2.86;对照组血清钙含量为8.72±0.58,血清磷含量为4.44±0.59,血清维生素D含量为32.51±6.92。结论:我们的研究发现,与暴露在阳光下的重度劳动女性相比,暴露在阳光下较少的女性血清钙、磷和维生素D水平显著降低。因此,我们可以得出结论,维持正常水平的维生素D不仅与充足的阳光照射和运动有关,还与饮食习惯有关。
{"title":"Comparison of Calcium, Phosphorous and 25 (OH)D2 Levels in Sedentary and Labourer Females","authors":"M. Bashir, B. K. Gupta, Omar Naushad, Nilesh Ch, ra, Abhishek Gupta","doi":"10.21767/2386-5180.100289","DOIUrl":"https://doi.org/10.21767/2386-5180.100289","url":null,"abstract":"Aim: To compare serum calcium, serum phosphorous and serum 25 (OH)D2 levels in sedentary less exposed to sun and heavy working females exposed to sun. Materials and methods: The study was performed in the Biochemistry Department, Subharti Medical College, Swami Vivekananda Subharti University, Meerut. 50 females, 21-50 years of age as labourers (control); 50 other healthy females of same age group sedentary ( cases) were included. All the samples were processed in related automatic machines Vidas and Vitros 350/Fusion by Biomerieux. Results: In our study we found that the levels of serum calcium were 7.25 ± 1.14, serum phosphorous 3.99 ± 0.69 and vitamin D 8.39 ± 2.86 in cases and levels of serum calcium were 8.72 ± 0.58, phosphorous 4.44 ± 0.59 and vitamin D 32.51 ± 6.92 in the control group respectively. Conclusion: Our study perceived that the level of serum Calcium, Phosphorus and vitamin D were significantly decreased in females, less exposed to sun as compared to heavy working females exposed to sun. Thus we could conclude that the maintenance of normal levels of vitamin D is contributed not only by adequate exposure to sun light and exercise, but also to the dietary habits.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72919995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Post-operative Analgesic Characteristics of Intrathecal Adjuvant AgentsIncluding Ketamine, Fentanyl, Sufentanyl, Neostigmine, Dexmedetomidine, Midazolame and Droperidole and their Effects on Spinal Anesthesia 氯胺酮、芬太尼、舒芬太尼、新斯的明、右美托咪定、咪达唑仑、卓哌啶等鞘内佐剂术后镇痛特点及其对脊髓麻醉的影响
Pub Date : 2019-01-01 DOI: 10.21767/2386-5180.100288
A. Yektaş
Aim: This study was designed to compare the intraoperative, postoperative analgesic characteristics and adverse effects of intrathecal combinations of several adjuvant agents combined with hyperbaric bupivacaine in the cases who underwent spinal anaesthesia. Materials and methods: 180 cases were randomized to 9 groups of 20 cases (n=20). 15 mg of 0.5% hyperbaric bupivacaine and 0.5 ml of serum physiological were administrated to the control group (group-0). In the other groups, instead of serum physiological: Group-1 (2.5 mg hyperbaric bupivacaine), Group-2 (12.5 mg ketamine), Group-3 (25 μgr Fentanyl), Group-4 (2.5 μg sufentanyl), Group-5 (2 μg dexmedetomidine), Group-6 (250 μg neostigmine), Group-7 (500 μg midazolame), Group-8 (1.25 mg Droperidole) were combined with hyperbaric bupivacaine. Total spinal drug volume was 3.5 ml. Intraoperative and postoperative side effects, time to the first pain, and the characteristics of spinal anaesthesia were recorded. Results: Intrathecal adjuvant agents had no effects on the characteristics of the spinal anaesthesia (p>0.05). Time to the first pain was similar between the groups (p>0.05). The most common side effect was pruritus in Group-3 and Group-4 (p>0.05), nausea-vomiting in Group-6 (p>0.05), urinary retention in Group-2 and Group-4 (p>0.05), and PSBA in Group-1 and Group-3 (p>0.05). Discussion: No differences in the time to the first pain were found between intrathecal adjuvant agents. Their effects on the characteristics of spinal anaesthesia were similar. Each adjuvant agent causes specific side effects. However, postoperative analgesic requirement was not considered in our study, and dose-finding studies (which are performed to determine the adjuvant agent doses that cause minimal and maximal side effects) were not performed. Further studies should be performed to evaluate those factors.
目的:本研究旨在比较脊髓麻醉患者鞘内联合几种佐剂联合高压布比卡因的术中、术后镇痛特点及不良反应。材料与方法:180例患者随机分为9组,每组20例(n=20)。对照组(0组)给予0.5%高压布比卡因15 mg,血清生理盐水0.5 ml。其他组以血清生理替代:1组(高压布比卡因2.5 mg)、2组(氯胺酮12.5 mg)、3组(芬太尼25 μg)、4组(舒芬太尼2.5 μg)、5组(右美托咪定2 μg)、6组(新斯的明250 μg)、7组(咪达唑胺500 μg)、8组(卓哌啶1.25 mg)联合使用高压布比卡因。脊髓药物总容量为3.5 ml。记录术中、术后不良反应、首次疼痛时间及脊髓麻醉特点。结果:鞘内佐剂对脊髓麻醉特征无影响(p < 0.05)。两组间首次疼痛时间差异无统计学意义(p < 0.05)。最常见的不良反应为3、4组瘙痒(p>0.05)、6组恶心呕吐(p>0.05)、2、4组尿潴留(p>0.05)、1、3组PSBA (p>0.05)。讨论:鞘内佐剂在首次疼痛的时间上没有差异。它们对脊髓麻醉特征的影响相似。每种佐剂都会产生特定的副作用。然而,我们的研究没有考虑术后镇痛需求,也没有进行剂量发现研究(用于确定引起最小和最大副作用的佐剂剂量)。应该进行进一步的研究来评价这些因素。
{"title":"Post-operative Analgesic Characteristics of Intrathecal Adjuvant AgentsIncluding Ketamine, Fentanyl, Sufentanyl, Neostigmine, Dexmedetomidine, Midazolame and Droperidole and their Effects on Spinal Anesthesia","authors":"A. Yektaş","doi":"10.21767/2386-5180.100288","DOIUrl":"https://doi.org/10.21767/2386-5180.100288","url":null,"abstract":"Aim: This study was designed to compare the intraoperative, postoperative analgesic characteristics and adverse effects of intrathecal combinations of several adjuvant agents combined with hyperbaric bupivacaine in the cases who underwent spinal anaesthesia. Materials and methods: 180 cases were randomized to 9 groups of 20 cases (n=20). 15 mg of 0.5% hyperbaric bupivacaine and 0.5 ml of serum physiological were administrated to the control group (group-0). In the other groups, instead of serum physiological: Group-1 (2.5 mg hyperbaric bupivacaine), Group-2 (12.5 mg ketamine), Group-3 (25 μgr Fentanyl), Group-4 (2.5 μg sufentanyl), Group-5 (2 μg dexmedetomidine), Group-6 (250 μg neostigmine), Group-7 (500 μg midazolame), Group-8 (1.25 mg Droperidole) were combined with hyperbaric bupivacaine. Total spinal drug volume was 3.5 ml. Intraoperative and postoperative side effects, time to the first pain, and the characteristics of spinal anaesthesia were recorded. Results: Intrathecal adjuvant agents had no effects on the characteristics of the spinal anaesthesia (p>0.05). Time to the first pain was similar between the groups (p>0.05). The most common side effect was pruritus in Group-3 and Group-4 (p>0.05), nausea-vomiting in Group-6 (p>0.05), urinary retention in Group-2 and Group-4 (p>0.05), and PSBA in Group-1 and Group-3 (p>0.05). Discussion: No differences in the time to the first pain were found between intrathecal adjuvant agents. Their effects on the characteristics of spinal anaesthesia were similar. Each adjuvant agent causes specific side effects. However, postoperative analgesic requirement was not considered in our study, and dose-finding studies (which are performed to determine the adjuvant agent doses that cause minimal and maximal side effects) were not performed. Further studies should be performed to evaluate those factors.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79085424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Effects of Levobupivacaine at Different Doses with Fentanyl added on Intrathecal Anaesthesia for Cesarean Section 不同剂量左布比卡因加芬太尼对剖宫产术鞘内麻醉的影响
Pub Date : 2019-01-01 DOI: 10.21767/2386-5180.100286
Bedih Balkan, A. Yektaş
Aim: The main aim of this study is to investigate the effect of levobupivacaine at different doses with fentanyl added on intrathecal anaesthesia in cesarean section. Materials and methods: This study is randomized, prospective and double-blind. Patients were divided into 3 groups (n=24 per group). Group 1: 11 mg levobupivacaine intrathecal, Group 2: 8 mg levobupivacaine+25 microgram fentanyl intrathecal and Group 3: 6 mg levobupivacaine+25 mg fentanyl intrathecal. Spinal anaesthesia start time, sensorial block time, motor block time, satisfaction of surgeon, satisfaction of patient, and analgesic consumption was recorded. The three groups were compared in terms of these values. Results: Motor block time in Group 1 was statistically longer than Group 3. Additional analgesic requirements in Group 1 were statistically less than Group 2 and 3 at the end of surgery. Conclusion: CSEA is gold standard for cesarean section. If local anesthetic dose is reduced anesthetic quality decreases, analgesic requirements increase and motor block recovery is shortened.
目的:探讨不同剂量左布比卡因加芬太尼对剖宫产术鞘内麻醉的影响。材料与方法:本研究采用随机、前瞻性、双盲方法。患者分为3组,每组24例。组1:左布比卡因鞘内11 mg,组2:左布比卡因鞘内8 mg +25微克芬太尼,组3:左布比卡因鞘内6 mg +芬太尼25 mg。记录脊髓麻醉开始时间、感觉阻滞时间、运动阻滞时间、外科医生满意度、患者满意度、镇痛药用量。根据这些值对三组进行比较。结果:1组运动阻滞时间明显长于3组。在手术结束时,组1的额外镇痛需求在统计学上少于组2和组3。结论:CSEA是剖宫产手术的金标准。如果局部麻醉剂量减少,麻醉质量下降,镇痛需求增加,运动阻滞恢复时间缩短。
{"title":"Effects of Levobupivacaine at Different Doses with Fentanyl added on Intrathecal Anaesthesia for Cesarean Section","authors":"Bedih Balkan, A. Yektaş","doi":"10.21767/2386-5180.100286","DOIUrl":"https://doi.org/10.21767/2386-5180.100286","url":null,"abstract":"Aim: The main aim of this study is to investigate the effect of levobupivacaine at different doses with fentanyl added on intrathecal anaesthesia in cesarean section. Materials and methods: This study is randomized, prospective and double-blind. Patients were divided into 3 groups (n=24 per group). Group 1: 11 mg levobupivacaine intrathecal, Group 2: 8 mg levobupivacaine+25 microgram fentanyl intrathecal and Group 3: 6 mg levobupivacaine+25 mg fentanyl intrathecal. Spinal anaesthesia start time, sensorial block time, motor block time, satisfaction of surgeon, satisfaction of patient, and analgesic consumption was recorded. The three groups were compared in terms of these values. Results: Motor block time in Group 1 was statistically longer than Group 3. Additional analgesic requirements in Group 1 were statistically less than Group 2 and 3 at the end of surgery. Conclusion: CSEA is gold standard for cesarean section. If local anesthetic dose is reduced anesthetic quality decreases, analgesic requirements increase and motor block recovery is shortened.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"88 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83085059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
An Assessment of Acceptance of Results as Generated by Clinical Laboratories in Mandeville Jamaica: A Perspective of Physicians Operating in Mandeville 对牙买加曼德维尔临床实验室产生的结果的接受度评估:曼德维尔医生的视角
Pub Date : 2019-01-01 DOI: 10.21767/2386-5180.100301
F. Pitkin
Physicians have received test results from laboratories which they deemed questionable and believe accepting such results could pose variable risk to the care of patients. The purpose of this study is to evaluate the physicians’ acceptance and confidence in results generated by the laboratories in Mandeville and to identify the factors contributing to or associated with the determined level of acceptance and confidence. The study used a population survey to collect data from twenty –six (26) participants from the public and private medical practices around the town of Mandeville. The correlation between the number of repeated tests (dependent variable) and the level of acceptance of patient result was evaluated, r=1, p<0.001. Approximately 100% of the participants scored their level of acceptance of patient results between 7 and 9 out of 10 with a mean score of 8.5 and median score 9. There was a strong correlation (r= 1, p<0.001) between years of experience and the frequency with which tests were repeated. Laboratory accreditation and compliance with standards are two of the most important tools influencing accuracy of laboratory tests and ultimately test result. The quality of laboratory test result impact patient treatment and will determine physicians’ level of acceptance and confidence in the report generated.
医生们收到了他们认为有问题的实验室的检测结果,并认为接受这样的结果可能会给病人的护理带来各种风险。本研究的目的是评估医生对曼德维尔实验室产生的结果的接受程度和信心,并确定影响或与确定的接受程度和信心相关的因素。这项研究通过人口调查收集了来自曼德维尔镇周围公共和私人医疗机构的26名参与者的数据。评估重复检测次数(因变量)与患者结果接受程度的相关性,r=1, p<0.001。大约100%的参与者对患者结果的接受程度评分在7到9分之间,平均得分为8.5分,中位数得分为9分。经验年数与重复测试的频率之间存在很强的相关性(r= 1, p<0.001)。实验室认可和符合标准是影响实验室测试准确性和最终测试结果的两个最重要的工具。实验室检测结果的质量影响患者的治疗,并将决定医生对所生成报告的接受程度和信心。
{"title":"An Assessment of Acceptance of Results as Generated by Clinical Laboratories in Mandeville Jamaica: A Perspective of Physicians Operating in Mandeville","authors":"F. Pitkin","doi":"10.21767/2386-5180.100301","DOIUrl":"https://doi.org/10.21767/2386-5180.100301","url":null,"abstract":"Physicians have received test results from laboratories which they deemed questionable and believe accepting such results could pose variable risk to the care of patients. The purpose of this study is to evaluate the physicians’ acceptance and confidence in results generated by the laboratories in Mandeville and to identify the factors contributing to or associated with the determined level of acceptance and confidence. The study used a population survey to collect data from twenty –six (26) participants from the public and private medical practices around the town of Mandeville. The correlation between the number of repeated tests (dependent variable) and the level of acceptance of patient result was evaluated, r=1, p<0.001. Approximately 100% of the participants scored their level of acceptance of patient results between 7 and 9 out of 10 with a mean score of 8.5 and median score 9. There was a strong correlation (r= 1, p<0.001) between years of experience and the frequency with which tests were repeated. Laboratory accreditation and compliance with standards are two of the most important tools influencing accuracy of laboratory tests and ultimately test result. The quality of laboratory test result impact patient treatment and will determine physicians’ level of acceptance and confidence in the report generated.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76103427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of Some Haematological Parameters in Pregnant Women with Gestational Diabetes at Federal Medical Center, Owerri, Imo State, Nigeria 尼日利亚伊莫州奥韦里联邦医疗中心妊娠期糖尿病孕妇血液学指标调查
Pub Date : 2019-01-01 DOI: 10.21767/2386-5180.100305
O. Hope, O. E. Ifeanyi, N. AnaeboQueenBraxton
This study was conducted to investigate some haematological parameters in pregnant women with Gestational Diabetes at FMC, Owerri, Imo state. Seventy (70) pregnant women were recruited in the study of which fifty (50) are suffering from gestational diabetes, while twenty (20) are normal pregnant women serving as the control. Haematoloical parameters were determined using standard haematological procedures, data obtained from the study were analysed using the SSPS package. Haemoglobin concentration was significantly (p 0.05) in the mean value of eosinophil count in gestational diabetic women (0.28 + 0.54%) when compared with the control subjects (0.20 + 0.41%). Basophils were not seen in gestational diabetic women and the control subjects. Lymphocyte count was significantly (p<0.05) r educed in gestational diabetic women (45.78 ± 09.92%) when compared with the control subject (56.70 + 5.32%). There was no statistically significant difference (p<0.05) in the mean value of lymphocyte count in gestational diabetic women (0.10 + 0.00%) when compared with the control subjects (0.30 + 0.00%). In conclusion, gestational diabetes has a significant effect on some haematological parameters.
本研究旨在调查伊莫州奥韦里FMC妊娠期糖尿病孕妇的一些血液学参数。研究招募了70名孕妇,其中50名患有妊娠期糖尿病,20名正常孕妇作为对照组。血液学参数使用标准血液学程序确定,从研究中获得的数据使用SSPS包进行分析。妊娠期糖尿病妇女嗜酸性粒细胞计数平均值(0.28 + 0.54%)与对照组(0.20 + 0.41%)相比,血红蛋白浓度差异有统计学意义(p 0.05)。妊娠期糖尿病妇女和对照组未见嗜碱性粒细胞。妊娠期糖尿病妇女淋巴细胞计数(45.78±09.92%)较对照组(56.70 + 5.32%)显著降低(p<0.05)。妊娠期糖尿病妇女淋巴细胞计数平均值(0.10 + 0.00%)与对照组(0.30 + 0.00%)比较,差异无统计学意义(p<0.05)。综上所述,妊娠期糖尿病对一些血液学参数有显著影响。
{"title":"Investigation of Some Haematological Parameters in Pregnant Women with Gestational Diabetes at Federal Medical Center, Owerri, Imo State, Nigeria","authors":"O. Hope, O. E. Ifeanyi, N. AnaeboQueenBraxton","doi":"10.21767/2386-5180.100305","DOIUrl":"https://doi.org/10.21767/2386-5180.100305","url":null,"abstract":"This study was conducted to investigate some haematological parameters in pregnant women with Gestational Diabetes at FMC, Owerri, Imo state. Seventy (70) pregnant women were recruited in the study of which fifty (50) are suffering from gestational diabetes, while twenty (20) are normal pregnant women serving as the control. Haematoloical parameters were determined using standard haematological procedures, data obtained from the study were analysed using the SSPS package. Haemoglobin concentration was significantly (p 0.05) in the mean value of eosinophil count in gestational diabetic women (0.28 + 0.54%) when compared with the control subjects (0.20 + 0.41%). Basophils were not seen in gestational diabetic women and the control subjects. Lymphocyte count was significantly (p<0.05) r educed in gestational diabetic women (45.78 ± 09.92%) when compared with the control subject (56.70 + 5.32%). There was no statistically significant difference (p<0.05) in the mean value of lymphocyte count in gestational diabetic women (0.10 + 0.00%) when compared with the control subjects (0.30 + 0.00%). In conclusion, gestational diabetes has a significant effect on some haematological parameters.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76163838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
A Jot of Blood Sends Constable behind the Bars - Justice by DNA Profiling 一滴血把警察送进监狱——DNA分析的正义
Pub Date : 2019-01-01 DOI: 10.21767/2386-5180.100306
Vaishali B. Mahajan, Anjali P. Kharade, Deepak Y. Kudekar, B. More, K. V. Kulkarni
It is difficult to identify a criminal just by examining the trace of blood on crime site and the garments. In sexual offences, specifically semen on victim’s clothes or biological samples proves involvement of accused in the crime. But in some cases where contraceptive devices are used or semen stains are not detected during investigation, the victim’s blood or body fluid on the accused’s garments helps to prove the crime. It is difficult to prove the evidence by routine ABO grouping in most of the cases because of the less quantity of blood. Further, discrimination power of ABO Blood group system is less. Here, DNA profiling technique has created wonders from the time it has been invented. Once the DNA technique proves involvement of the accused, there is provision of ‘Protection of Children from Sexual Offences ’ (POCSO) Act 2012 in the court to effectively address the heinous crimes. Also, there is provision of Atrocity Act to provide justice to SC/ST communities in order to enable them to live in the society with dignity without suppression from the dominant castes. In the instant case, a girl aged 11, promising to drop to the school on motor cycle was raped by Police Constable aged 41. Just 2 cm blood stain was found on his undergarment and few blood stains were found on his handkerchief at the crime scene. As the DNA profiling proved his involvement in the crime, Hon ’ ble court convicted him with rigorous imprisonment for 10 years and to pay a fine of Rs. 2000/- under the provision of POCSO Act and Atrocity Act.
仅凭犯罪现场和服装上的血迹很难识别罪犯。在性犯罪中,特别是受害者衣服上的精液或生物样本可以证明被告参与了犯罪。但在一些使用避孕装置或在调查过程中未发现精液污点的案件中,受害人衣服上的血液或体液有助于证明犯罪。由于血量少,多数病例常规ABO分型难以证明证据。此外,ABO血型系统的辨别力较小。在这里,DNA分析技术从发明之日起就创造了奇迹。一旦DNA技术证明被告参与其中,法院就会根据2012年“保护儿童免受性犯罪”(POCSO)法案的规定,有效地解决这些令人发指的罪行。此外,还有《反暴行法》的规定,为SC/ST社区提供正义,使他们能够有尊严地生活在社会中,而不受主导种姓的压迫。在这起案件中,一名11岁的女孩承诺骑摩托车去学校,被41岁的警察强奸。在他的内衣上只发现了2厘米的血迹,在犯罪现场的手帕上也发现了少量血迹。由于DNA分析证明了他参与了犯罪,因此,根据《POCSO法》和《暴行法》的规定,法院判处他10年严厉监禁,并处以2000卢比的罚款。
{"title":"A Jot of Blood Sends Constable behind the Bars - Justice by DNA Profiling","authors":"Vaishali B. Mahajan, Anjali P. Kharade, Deepak Y. Kudekar, B. More, K. V. Kulkarni","doi":"10.21767/2386-5180.100306","DOIUrl":"https://doi.org/10.21767/2386-5180.100306","url":null,"abstract":"It is difficult to identify a criminal just by examining the trace of blood on crime site and the garments. In sexual offences, specifically semen on victim’s clothes or biological samples proves involvement of accused in the crime. But in some cases where contraceptive devices are used or semen stains are not detected during investigation, the victim’s blood or body fluid on the accused’s garments helps to prove the crime. It is difficult to prove the evidence by routine ABO grouping in most of the cases because of the less quantity of blood. Further, discrimination power of ABO Blood group system is less. Here, DNA profiling technique has created wonders from the time it has been invented. Once the DNA technique proves involvement of the accused, there is provision of ‘Protection of Children from Sexual Offences ’ (POCSO) Act 2012 in the court to effectively address the heinous crimes. Also, there is provision of Atrocity Act to provide justice to SC/ST communities in order to enable them to live in the society with dignity without suppression from the dominant castes. In the instant case, a girl aged 11, promising to drop to the school on motor cycle was raped by Police Constable aged 41. Just 2 cm blood stain was found on his undergarment and few blood stains were found on his handkerchief at the crime scene. As the DNA profiling proved his involvement in the crime, Hon ’ ble court convicted him with rigorous imprisonment for 10 years and to pay a fine of Rs. 2000/- under the provision of POCSO Act and Atrocity Act.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83279909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of Interferon-Gamma, Interleukin 6 and Interleukin 10 in TuberculosisPatients in Umuahia 结核病患者干扰素- γ、白细胞介素6和白细胞介素10的评价
Pub Date : 2019-01-01 DOI: 10.21767/2386-5180.100307
Obeagu Ei, Okoroiwu Il, N. Hu, N. Dc
Tuberculosis has been a great threat to mankind and has been defying treatments. Tuberculosis presents with a lot of changes in the system of the patients. This study was done to determine the levels of interferon-gamma, interleukins of the tuberculosis patients in TB directly observed treatmentshort course (TB DOTS) center of FMC, Umuahia. A total of 150 subjects aged 18-60 years were enlisted for this study. The subjects were grouped into: Group A (50 control subjects) and Group B (100 TB Subjects). About 4.5 ml of blood were collected into plain tubes for assay of interferon gamma and interleukins (6 and 10). The cytokines were measured using MELNI ELISA Kits. The results were expressed as mean ± SD. The data was analyzed with the statistical package for social science (SPSS) version 20 using ANOVA the level of significance set at P 0.05) in TB group on 6 months treatment (8.66 ± 1.12 pg/ml) compared to the control group (7.98 ± 0.22 pg/ml).There was significant decrease (P<0.05) in IL-10 with increasing months of treatment (2 months, 4 months, 6 months on treatment) for TB subgroups based on the duration of treatment (21.06 ± 2.84 pg/ml, 18.93 ± 1.34 pg/ml, 15.08 ± 1.12 pg/ml, 10.62 ± 1.19 pg/ml). The results showed significant decrease in IFN-γ, IL-6 and IL-10 with increase in duration of treatment of the TB patients. The study shows that IFN-γ, IL-6 and IL-10 are some of the biomarkers in the pathogenesis of TB The cytokines can be used as prognostic and diagnostic markers as their levels decreased with increased duration of treatment of the patients.
结核病一直是对人类的巨大威胁,而且一直无法治愈。结核病在患者的系统中表现出许多变化。本研究旨在测定Umuahia FMC结核病直接观察短程治疗(TB DOTS)中心结核病患者的干扰素- γ、白细胞介素水平。本研究共招募了150名年龄在18-60岁之间的受试者。研究对象分为:A组(50名对照)和B组(100名TB受试者)。采集约4.5 ml的血液,放入平管中检测干扰素γ和白细胞介素(6和10)。采用MELNI ELISA试剂盒检测细胞因子。结果以mean±SD表示。采用社会科学统计软件包(SPSS) version 20对数据进行方差分析(P < 0.05),治疗6个月时结核组(8.66±1.12 pg/ml)与对照组(7.98±0.22 pg/ml)比较差异有统计学意义。根据治疗时间(21.06±2.84 pg/ml, 18.93±1.34 pg/ml, 15.08±1.12 pg/ml, 10.62±1.19 pg/ml),结核亚组IL-10随治疗时间(治疗2个月,4个月,6个月)的增加而显著降低(P<0.05)。结果显示,随着结核病患者治疗时间的延长,IFN-γ、IL-6和IL-10水平显著降低。研究表明,IFN-γ、IL-6和IL-10是TB发病机制中的一些生物标志物,随着治疗时间的延长,这些细胞因子的水平降低,可作为预后和诊断标志物。
{"title":"Evaluation of Interferon-Gamma, Interleukin 6 and Interleukin 10 in TuberculosisPatients in Umuahia","authors":"Obeagu Ei, Okoroiwu Il, N. Hu, N. Dc","doi":"10.21767/2386-5180.100307","DOIUrl":"https://doi.org/10.21767/2386-5180.100307","url":null,"abstract":"Tuberculosis has been a great threat to mankind and has been defying treatments. Tuberculosis presents with a lot of changes in the system of the patients. This study was done to determine the levels of interferon-gamma, interleukins of the tuberculosis patients in TB directly observed treatmentshort course (TB DOTS) center of FMC, Umuahia. A total of 150 subjects aged 18-60 years were enlisted for this study. The subjects were grouped into: Group A (50 control subjects) and Group B (100 TB Subjects). About 4.5 ml of blood were collected into plain tubes for assay of interferon gamma and interleukins (6 and 10). The cytokines were measured using MELNI ELISA Kits. The results were expressed as mean ± SD. The data was analyzed with the statistical package for social science (SPSS) version 20 using ANOVA the level of significance set at P 0.05) in TB group on 6 months treatment (8.66 ± 1.12 pg/ml) compared to the control group (7.98 ± 0.22 pg/ml).There was significant decrease (P<0.05) in IL-10 with increasing months of treatment (2 months, 4 months, 6 months on treatment) for TB subgroups based on the duration of treatment (21.06 ± 2.84 pg/ml, 18.93 ± 1.34 pg/ml, 15.08 ± 1.12 pg/ml, 10.62 ± 1.19 pg/ml). The results showed significant decrease in IFN-γ, IL-6 and IL-10 with increase in duration of treatment of the TB patients. The study shows that IFN-γ, IL-6 and IL-10 are some of the biomarkers in the pathogenesis of TB The cytokines can be used as prognostic and diagnostic markers as their levels decreased with increased duration of treatment of the patients.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88922098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Giant Scrotal Lymphedema: A Presentation of Rare Urogenital Disease - A Case Report 巨大阴囊淋巴水肿:一种罕见泌尿生殖系统疾病的表现- 1例报告
Pub Date : 2019-01-01 DOI: 10.21767/2386-5180.100292
Tillyashaykhov Mn, B. Ye, Aloev Bb, Abdusamatov Nt, T. KhasanovSh, Tillyashaykhova Rm, Ziyaev Yf, Ubaydullaeva Ho
We report a case of 21-year-old man with scrotal lymphedema which weight was 36 kg. The patient has been undergone surgery where we completely removed the affected tissue, after this intervention we achieved good outcomes and increased the quality of patient’s life. Giant Scrotal lymphedema is ill health which inflict physical and psychological damage on the patient. So total surgical excision the affected tissue with reconstruction is a principal method of advanced scrotal lymphedema.
我们报告一例21岁男性阴囊淋巴水肿,体重36公斤。患者已经接受了手术,我们完全切除了受影响的组织,经过这次干预,我们取得了良好的效果,提高了患者的生活质量。巨大阴囊淋巴水肿是一种不健康的疾病,会对患者的身体和心理造成伤害。因此手术切除受损组织并重建是晚期阴囊淋巴水肿的主要治疗方法。
{"title":"Giant Scrotal Lymphedema: A Presentation of Rare Urogenital Disease - A Case Report","authors":"Tillyashaykhov Mn, B. Ye, Aloev Bb, Abdusamatov Nt, T. KhasanovSh, Tillyashaykhova Rm, Ziyaev Yf, Ubaydullaeva Ho","doi":"10.21767/2386-5180.100292","DOIUrl":"https://doi.org/10.21767/2386-5180.100292","url":null,"abstract":"We report a case of 21-year-old man with scrotal lymphedema which weight was 36 kg. The patient has been undergone surgery where we completely removed the affected tissue, after this intervention we achieved good outcomes and increased the quality of patient’s life. Giant Scrotal lymphedema is ill health which inflict physical and psychological damage on the patient. So total surgical excision the affected tissue with reconstruction is a principal method of advanced scrotal lymphedema.","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79789559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Thrift Shop Hemostasis: Iâm Going To Pop Some Hemostats, Only Got 20 Dollars In My Pocket! 旧货店止血:我要用一些止血器,我口袋里只有20美元!
Pub Date : 2019-01-01 DOI: 10.21767/2386-5180.100282
Harsh Deora, Nishant S. Yagnick, M. Tripathi, Ram, E. Singh, eep Mohindra, A. Suri, SUNIL K Gupta
{"title":"Thrift Shop Hemostasis: Iâm Going To Pop Some Hemostats, Only Got 20 Dollars In My Pocket!","authors":"Harsh Deora, Nishant S. Yagnick, M. Tripathi, Ram, E. Singh, eep Mohindra, A. Suri, SUNIL K Gupta","doi":"10.21767/2386-5180.100282","DOIUrl":"https://doi.org/10.21767/2386-5180.100282","url":null,"abstract":"","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76531241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Effectiveness of Community-Directed Intervention in the Roll-Back Malaria among the Under-Five Population of the Ndop Health District in North West Cameroon 在喀麦隆西北部恩多普卫生区五岁以下儿童中减少疟疾的社区指导干预的有效性
Pub Date : 2019-01-01 DOI: 10.21767/2386-5180.100277
Bodzewan Emmanuel Fonyuy, M. Sirri, Mme Kyeng Mercy, Dymphna Bi Ndifor
Community-directed Intervention (CDI) is an intervention approach in which communities themselves direct and execute the planning and implementation of a health intervention. The success of this approach for the intervention of Onchocerciasis led to the extension of the strategy for the intervention of the other diseases in Africa. Community Health Workers (CHWs) working under the CDI of malaria program play a vital role in primary health care of the community. Local health services and partners initially introduce the intervention and explain the community-directed approach and how it can be planned, run and controlled by the community. This project was aimed at assessing the effectiveness of the implementation of the CDI in the roll-back of malaria among under-five children in the Ndop Health District, with special emphasis of the home management of malaria (HMM) by the Community Health Workers (CHWs). Among the CHW involved in the study, 94.7% of them accepted to receive monetary incentive for their services as CHW. Up to 39.8% of them had no other source of income. Furthermore, 74.3% of the participants reported that they have regular monthly meetings with their supervisor while 25.6% of them had either irregularly-scheduled meetings or none. While 76.1% of respondents accepted to have had at least one refresher course since working under the CDI of malaria program, 23.9% reported to have never had one. While 43.3% of the respondents found their workload okay, 8.9% of them reported they were overworked. A majority (47.8%) of the respondents reported that they found their workload as community health workers manageable. While majority of the respondents reported irregularity in the supply of both antimalarial drugs (64.6%) and RDT kits (73.5%), a majority of them said the supply of registers for records and the provision of transportation means were regular (71.7% and 69% respectively).
社区指导干预(CDI)是一种干预方法,由社区自己指导和执行卫生干预的规划和实施。这种方法在防治盘尾丝虫病方面取得的成功,导致扩大了防治非洲其他疾病的战略。社区卫生工作者(CHWs)在疟疾方案的CDI下工作,在社区的初级卫生保健中发挥着至关重要的作用。地方卫生服务机构和合作伙伴首先介绍干预措施,并解释以社区为导向的做法,以及如何由社区规划、运行和控制。该项目旨在评估在恩多普卫生区实施《社区发展倡议》减少五岁以下儿童疟疾的效果,特别强调社区卫生工作者的家庭疟疾管理。在参与研究的医护人员中,有94.7%的医护人员表示会因提供医护服务而获得金钱奖励。高达39.8%的人没有其他收入来源。此外,74.3%的参与者报告说,他们每月定期与主管开会,而25.6%的人要么不定期开会,要么没有开会。76.1%的受访者承认在疟疾项目的CDI下工作以来至少参加过一次进修课程,23.9%的受访者表示从未参加过。虽然43.3%的受访者认为他们的工作量还可以,但8.9%的人表示他们超负荷工作。大多数答复者(47.8%)报告说,他们发现自己作为社区卫生工作者的工作量是可控的。虽然大多数答复者报告抗疟药物(64.6%)和RDT试剂盒(73.5%)的供应不正常,但大多数答复者表示记录登记册的供应和运输工具的提供是正常的(分别为71.7%和69%)。
{"title":"Effectiveness of Community-Directed Intervention in the Roll-Back Malaria among the Under-Five Population of the Ndop Health District in North West Cameroon","authors":"Bodzewan Emmanuel Fonyuy, M. Sirri, Mme Kyeng Mercy, Dymphna Bi Ndifor","doi":"10.21767/2386-5180.100277","DOIUrl":"https://doi.org/10.21767/2386-5180.100277","url":null,"abstract":"Community-directed Intervention (CDI) is an intervention approach in which communities themselves direct and execute the planning and implementation of a health intervention. The success of this approach for the intervention of Onchocerciasis led to the extension of the strategy for the intervention of the other diseases in Africa. Community Health Workers (CHWs) working under the CDI of malaria program play a vital role in primary health care of the community. Local health services and partners initially introduce the intervention and explain the community-directed approach and how it can be planned, run and controlled by the community. This project was aimed at assessing the effectiveness of the implementation of the CDI in the roll-back of malaria among under-five children in the Ndop Health District, with special emphasis of the home management of malaria (HMM) by the Community Health Workers (CHWs). Among the CHW involved in the study, 94.7% of them accepted to receive monetary incentive for their services as CHW. Up to 39.8% of them had no other source of income. Furthermore, 74.3% of the participants reported that they have regular monthly meetings with their supervisor while 25.6% of them had either irregularly-scheduled meetings or none. While 76.1% of respondents accepted to have had at least one refresher course since working under the CDI of malaria program, 23.9% reported to have never had one. While 43.3% of the respondents found their workload okay, 8.9% of them reported they were overworked. A majority (47.8%) of the respondents reported that they found their workload as community health workers manageable. While majority of the respondents reported irregularity in the supply of both antimalarial drugs (64.6%) and RDT kits (73.5%), a majority of them said the supply of registers for records and the provision of transportation means were regular (71.7% and 69% respectively).","PeriodicalId":8195,"journal":{"name":"Annals of Clinical and Laboratory Research","volume":"117 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79229121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Annals of Clinical and Laboratory Research
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1